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Volumn 6, Issue , 2012, Pages 163-189

The effect of erythropoietin on normal and neoplastic cells

Author keywords

Anemia; Angiogenesis; Erythropoietin; Erythropoietin receptor; Tumor

Indexed keywords

ANTIANEMIC AGENT; ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; MESSENGER RNA; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN; RECOMBINANT ERYTHROPOIETIN;

EID: 84866748197     PISSN: 11775475     EISSN: 11775491     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (95)

References (462)
  • 1
    • 0026019106 scopus 로고
    • Erythropoietin
    • Krantz SB. Erythropoietin. Blood. 1991;77(3):419-434.
    • (1991) Blood , vol.77 , Issue.3 , pp. 419-434
    • Krantz, S.B.1
  • 2
    • 75549086280 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents in oncology: A study-level meta-analysis of survival and other safety outcomes
    • Glaspy J, Crawford J, Vansteenkiste J, et al. Erythropoiesis-stimulating agents in oncology: a study-level meta-analysis of survival and other safety outcomes. Br J Cancer. 2010;102(2):301-315.
    • (2010) Br J Cancer , vol.102 , Issue.2 , pp. 301-315
    • Glaspy, J.1    Crawford, J.2    Vansteenkiste, J.3
  • 3
    • 78650360689 scopus 로고    scopus 로고
    • Twist and shout: One decade of meta-analyses of erythropoiesis-stimulating agents in cancer patients
    • Bohlius J, Tonia T, Schwarzer G. Twist and shout: one decade of meta-analyses of erythropoiesis-stimulating agents in cancer patients. Acta Haematol. 2010;125(1-2):55-67.
    • (2010) Acta Haematol , vol.125 , Issue.1-2 , pp. 55-67
    • Bohlius, J.1    Tonia, T.2    Schwarzer, G.3
  • 4
    • 0002697931 scopus 로고    scopus 로고
    • Biology of erythropoiesis, erythroid maturation and differentiation
    • Hoffman R, Benz EJ, Shattil SJ, et al, editors, 3rd ed. Philadelphia: Churchill Livingston
    • Papayannopoulou T, Abkowitz J, D'Andrea A. Biology of erythropoiesis, erythroid maturation and differentiation. In: Hoffman R, Benz EJ, Shattil SJ, et al, editors. Hematology Basic Principals and Practice. 3rd ed. Philadelphia: Churchill Livingston; 2000:202-219.
    • (2000) Hematology Basic Principals and Practice , pp. 202-219
    • Papayannopoulou, T.1    Abkowitz, J.2    D'Andrea, A.3
  • 5
    • 0016039821 scopus 로고
    • Half-life and rate of synthesis of globin messenger ribonucleic acid. Determination of half-life of messenger ribonucleic acid and its relative synthetic rate in erythroid cells
    • Hunt JA. Half-life and rate of synthesis of globin messenger ribonucleic acid. Determination of half-life of messenger ribonucleic acid and its relative synthetic rate in erythroid cells. Biochem J. 1974;138(3): 487-498.
    • (1974) Biochem J , vol.138 , Issue.3 , pp. 487-498
    • Hunt, J.A.1
  • 6
    • 78650038693 scopus 로고    scopus 로고
    • During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool
    • Dev A, Fang J, Sathyanarayana P, Pradeep A, Emerson C, Wojchowski DM. During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool. Blood. 2010;116(24):5334-5346.
    • (2010) Blood , vol.116 , Issue.24 , pp. 5334-5346
    • Dev, A.1    Fang, J.2    Sathyanarayana, P.3    Pradeep, A.4    Emerson, C.5    Wojchowski, D.M.6
  • 7
    • 0005793375 scopus 로고
    • Cellular composition of the bone marrow in normal infants and children
    • Glaser K, Limarzi LR, Poncher HG. Cellular composition of the bone marrow in normal infants and children. Pediatrics. 1950;6(5): 789-824.
    • (1950) Pediatrics , vol.6 , Issue.5 , pp. 789-824
    • Glaser, K.1    Limarzi, L.R.2    Poncher, H.G.3
  • 8
    • 0023664340 scopus 로고
    • Binding and receptor-mediated endocytosis of erythropoietin in Friend virus-infected erythroid cells
    • Sawyer ST, Krantz SB, Goldwasser E. Binding and receptor-mediated endocytosis of erythropoietin in Friend virus-infected erythroid cells. J Biol Chem. 1987;262(12):5554-5562.
    • (1987) J Biol Chem , vol.262 , Issue.12 , pp. 5554-5562
    • Sawyer, S.T.1    Krantz, S.B.2    Goldwasser, E.3
  • 9
    • 0023758312 scopus 로고
    • Synergism between erythropoietin and interleukin-3 in the induction of hematopoietic stem cell proliferation and erythroid burst colony formation
    • Migliaccio G, Migliaccio AR, Visser JW. Synergism between erythropoietin and interleukin-3 in the induction of hematopoietic stem cell proliferation and erythroid burst colony formation. Blood. 1988;72(3):944-951.
    • (1988) Blood , vol.72 , Issue.3 , pp. 944-951
    • Migliaccio, G.1    Migliaccio, A.R.2    Visser, J.W.3
  • 10
    • 0029960947 scopus 로고    scopus 로고
    • Erythropoiesis in myelodysplastic syndrome: Expression of receptors for erythropoietin and kit ligand
    • Backx B, Broeders L, Hoefsloot LH, Wognum B, Lowenberg B. Erythropoiesis in myelodysplastic syndrome: expression of receptors for erythropoietin and kit ligand. Leukemia. 1996;10(3):466-472.
    • (1996) Leukemia , vol.10 , Issue.3 , pp. 466-472
    • Backx, B.1    Broeders, L.2    Hoefsloot, L.H.3    Wognum, B.4    Lowenberg, B.5
  • 11
    • 0025159230 scopus 로고
    • Purification of human blood burst-forming units-erythroid and demonstration of the evolution of erythropoietin receptors
    • Sawada K, Krantz SB, Dai CH, et al. Purification of human blood burst-forming units-erythroid and demonstration of the evolution of erythropoietin receptors. J Cell Physiol. 1990;142(2):219-230.
    • (1990) J Cell Physiol , vol.142 , Issue.2 , pp. 219-230
    • Sawada, K.1    Krantz, S.B.2    Dai, C.H.3
  • 12
    • 0028813090 scopus 로고
    • Exercise, training and red blood cell turnover
    • Smith JA. Exercise, training and red blood cell turnover. Sports Med. 1995;19(1):9-31.
    • (1995) Sports Med , vol.19 , Issue.1 , pp. 9-31
    • Smith, J.A.1
  • 13
    • 0024495259 scopus 로고
    • The anemia of chronic renal failure: Pathophysiology and the effects of recombinant erythropoietin
    • Eschbach JW. The anemia of chronic renal failure: pathophysiology and the effects of recombinant erythropoietin. Kidney Int. 1989; 35(1):134-148.
    • (1989) Kidney Int , vol.35 , Issue.1 , pp. 134-148
    • Eschbach, J.W.1
  • 14
    • 0022473616 scopus 로고
    • Chromosomal assignment of the human erythropoietin gene and its DNA polymorphism
    • Law ML, Cai GY, Lin FK, et al. Chromosomal assignment of the human erythropoietin gene and its DNA polymorphism. Proc Natl Acad Sci U S A. 1986;83(18):6920-6924.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , Issue.18 , pp. 6920-6924
    • Law, M.L.1    Cai, G.Y.2    Lin, F.K.3
  • 15
    • 0021978919 scopus 로고
    • Isolation and characterization of genomic and cDNA clones of human erythropoietin
    • Jacobs K, Shoemaker C, Rudersdorf R, et al. Isolation and characterization of genomic and cDNA clones of human erythropoietin. Nature. 1985;313(6005):806-810.
    • (1985) Nature , vol.313 , Issue.6005 , pp. 806-810
    • Jacobs, K.1    Shoemaker, C.2    Rudersdorf, R.3
  • 16
    • 0025823619 scopus 로고
    • Structure-function correlations in erythropoietin formation and oxygen sensing in the kidney
    • LeHir M, Eckardt KU, Kaissling B, Koury ST, Kurtz A. Structure-function correlations in erythropoietin formation and oxygen sensing in the kidney. Klin Wochenschr. 1991;69(13):567-575.
    • (1991) Klin Wochenschr , vol.69 , Issue.13 , pp. 567-575
    • Lehir, M.1    Eckardt, K.U.2    Kaissling, B.3    Koury, S.T.4    Kurtz, A.5
  • 17
    • 0023120533 scopus 로고
    • Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial
    • Eschbach JW, Egrie JC, Downing MR, Browne JK, Adamson JW. Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. New Engl J Med. 1987;316(2):73-78.
    • (1987) New Engl J Med , vol.316 , Issue.2 , pp. 73-78
    • Eschbach, J.W.1    Egrie, J.C.2    Downing, M.R.3    Browne, J.K.4    Adamson, J.W.5
  • 18
    • 10044237889 scopus 로고    scopus 로고
    • Control of rHuEPO biological activity: The role of carbohydrate
    • Elliott S, Egrie J, Browne J, et al. Control of rHuEPO biological activity: the role of carbohydrate. Exp Hematol. 2004;32(12):1146-1155.
    • (2004) Exp Hematol , vol.32 , Issue.12 , pp. 1146-1155
    • Elliott, S.1    Egrie, J.2    Browne, J.3
  • 19
    • 0022484262 scopus 로고
    • Characterization and biological effects of recombinant human erythropoietin
    • Egrie JC, Strickland TW, Lane J, et al. Characterization and biological effects of recombinant human erythropoietin. Immunobiology. 1986;172(3-5):213-224.
    • (1986) Immunobiology , vol.172 , Issue.3-5 , pp. 213-224
    • Egrie, J.C.1    Strickland, T.W.2    Lane, J.3
  • 20
    • 0026801369 scopus 로고
    • Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells
    • Wickrema A, Krantz SB, Winkelmann JC, Bondurant MC. Differentiation and erythropoietin receptor gene expression in human erythroid progenitor cells. Blood. 1992;80(8):1940-1949.
    • (1992) Blood , vol.80 , Issue.8 , pp. 1940-1949
    • Wickrema, A.1    Krantz, S.B.2    Winkelmann, J.C.3    Bondurant, M.C.4
  • 21
    • 0025343574 scopus 로고
    • Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells
    • Koury MJ, Bondurant MC. Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells. Science. 1990;248(4953):378-381.
    • (1990) Science , vol.248 , Issue.4953 , pp. 378-381
    • Koury, M.J.1    Bondurant, M.C.2
  • 24
    • 0029944965 scopus 로고    scopus 로고
    • Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1
    • Jiang BH, Rue E, Wang GL, Roe R, Semenza GL. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J Biol Chem. 1996;271(30):17771-17778.
    • (1996) J Biol Chem , vol.271 , Issue.30 , pp. 17771-17778
    • Jiang, B.H.1    Rue, E.2    Wang, G.L.3    Roe, R.4    Semenza, G.L.5
  • 25
    • 34147124264 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
    • Rankin EB, Biju MP, Liu Q et al. Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. J Clin Invest. 2007; 117(4):1068-1077.
    • (2007) J Clin Invest , vol.117 , Issue.4 , pp. 1068-1077
    • Rankin, E.B.1    Biju, M.P.2    Liu, Q.3
  • 26
    • 51649104761 scopus 로고    scopus 로고
    • The microenvironment for erythropoiesis is regulated by HIF-2alpha through VCAM-1 in endothelial cells
    • Yamashita T, Ohneda O, Sakiyama A, Iwata F, Ohneda K, Fujii-Kuriyama Y. The microenvironment for erythropoiesis is regulated by HIF-2alpha through VCAM-1 in endothelial cells. Blood. 2008;112(4):1482-1492.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1482-1492
    • Yamashita, T.1    Ohneda, O.2    Sakiyama, A.3    Iwata, F.4    Ohneda, K.5    Fujii-Kuriyama, Y.6
  • 27
    • 77958177671 scopus 로고    scopus 로고
    • Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
    • Kapitsinou PP, Liu Q, Unger TL, et al. Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. Blood. 2010; 116(16):3039-3048.
    • (2010) Blood , vol.116 , Issue.16 , pp. 3039-3048
    • Kapitsinou, P.P.1    Liu, Q.2    Unger, T.L.3
  • 28
    • 75749150800 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
    • Paliege A, Rosenberger C, Bondke A, et al. Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization. Kidney Int. 2010;77(4):312-318.
    • (2010) Kidney Int , vol.77 , Issue.4 , pp. 312-318
    • Paliege, A.1    Rosenberger, C.2    Bondke, A.3
  • 29
    • 17944375360 scopus 로고    scopus 로고
    • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
    • Epstein AC, Gleadle JM, McNeill LA, et al. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell. 2001;107(1):43-54.
    • (2001) Cell , vol.107 , Issue.1 , pp. 43-54
    • Epstein, A.C.1    Gleadle, J.M.2    McNeill, L.A.3
  • 30
    • 0035903468 scopus 로고    scopus 로고
    • Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation
    • Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J. 2001;20(18):5197-5206.
    • (2001) EMBO J , vol.20 , Issue.18 , pp. 5197-5206
    • Masson, N.1    Willam, C.2    Maxwell, P.H.3    Pugh, C.W.4    Ratcliffe, P.J.5
  • 31
    • 0035834409 scopus 로고    scopus 로고
    • A conserved family of prolyl-4-hydroxylases that modify HIF
    • Bruick RK, McKnight SL. A conserved family of prolyl-4-hydroxylases that modify HIF. Science. 2001;294(5545):1337-1340.
    • (2001) Science , vol.294 , Issue.5545 , pp. 1337-1340
    • Bruick, R.K.1    McKnight, S.L.2
  • 33
    • 18444368709 scopus 로고    scopus 로고
    • Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL
    • Hon WC, Wilson MI, Harlos K, et al. Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Nature. 2002; 417(6892):975-978.
    • (2002) Nature , vol.417 , Issue.6892 , pp. 975-978
    • Hon, W.C.1    Wilson, M.I.2    Harlos, K.3
  • 34
    • 0034936702 scopus 로고    scopus 로고
    • Insights into the role of the von Hippel-Lindau gene product. A key player in hypoxic regulation
    • Maxwell PH, Pugh CW, Ratcliffe PJ. Insights into the role of the von Hippel-Lindau gene product. A key player in hypoxic regulation. Exp Nephrol. 2001;9(4):235-240.
    • (2001) Exp Nephrol , vol.9 , Issue.4 , pp. 235-240
    • Maxwell, P.H.1    Pugh, C.W.2    Ratcliffe, P.J.3
  • 35
    • 0024322837 scopus 로고
    • Quantitation of erythropoietin-producing cells in kidneys of mice by in situ hybridization: Correlation with hematocrit, renal erythropoietin mRNA, and serum erythropoietin concentration
    • Koury ST, Koury MJ, Bondurant MC, Caro J, Graber SE. Quantitation of erythropoietin-producing cells in kidneys of mice by in situ hybridization: correlation with hematocrit, renal erythropoietin mRNA, and serum erythropoietin concentration. Blood. 1989;74(2):645-651.
    • (1989) Blood , vol.74 , Issue.2 , pp. 645-651
    • Koury, S.T.1    Koury, M.J.2    Bondurant, M.C.3    Caro, J.4    Graber, S.E.5
  • 36
    • 46749127450 scopus 로고    scopus 로고
    • Repression via the GATA box is essential for tissue-specific erythropoietin gene expression
    • Obara N, Suzuki N, Kim K, Nagasawa T, Imagawa S, Yamamoto M. Repression via the GATA box is essential for tissue-specific erythropoietin gene expression. Blood. 2008;111(10):5223-5232.
    • (2008) Blood , vol.111 , Issue.10 , pp. 5223-5232
    • Obara, N.1    Suzuki, N.2    Kim, K.3    Nagasawa, T.4    Imagawa, S.5    Yamamoto, M.6
  • 37
    • 0023185845 scopus 로고
    • Erythropoietin titers in anemic, nonuremic patients
    • Erslev AJ, Wilson J, Caro J. Erythropoietin titers in anemic, nonuremic patients. J Lab Clin Med. 1987;109(4):429-433.
    • (1987) J Lab Clin Med , vol.109 , Issue.4 , pp. 429-433
    • Erslev, A.J.1    Wilson, J.2    Caro, J.3
  • 38
    • 0030050404 scopus 로고    scopus 로고
    • Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis
    • Lin CS, Lim SK, D'Agati V, Costantini F. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev. 1996;10(2):154-164.
    • (1996) Genes Dev , vol.10 , Issue.2 , pp. 154-164
    • Lin, C.S.1    Lim, S.K.2    D'Agati, V.3    Costantini, F.4
  • 39
    • 0028211493 scopus 로고
    • Effect of recombinant human erythropoietin administration on peripheral blood neutrophil counts of premature infants
    • Mizuno S, Sasaki J, Suzuki C, Kono H, Kojima S. Effect of recombinant human erythropoietin administration on peripheral blood neutrophil counts of premature infants. J Pediatr. 1994;124(3):467-470.
    • (1994) J Pediatr , vol.124 , Issue.3 , pp. 467-470
    • Mizuno, S.1    Sasaki, J.2    Suzuki, C.3    Kono, H.4    Kojima, S.5
  • 40
    • 0025853956 scopus 로고
    • Recombinant human erythropoietin in the anemia of prematurity: Results of a placebo-controlled pilot study
    • Shannon KM, Mentzer WC, Abels RI, et al. Recombinant human erythropoietin in the anemia of prematurity: results of a placebo-controlled pilot study. J Pediatr. 1991;118(6):949-955.
    • (1991) J Pediatr , vol.118 , Issue.6 , pp. 949-955
    • Shannon, K.M.1    Mentzer, W.C.2    Abels, R.I.3
  • 41
    • 0026736140 scopus 로고
    • The in vitro effect of high-dose recombinant human erythropoietin on granulocyte-macrophage colony production in premature infants using a defined serum deprived cell culture system
    • Ward CS, Westwood NB, Emmerson AJ, Pearson TC. The in vitro effect of high-dose recombinant human erythropoietin on granulocyte-macrophage colony production in premature infants using a defined serum deprived cell culture system. Br J Haematol. 1992;81(3):325-330.
    • (1992) Br J Haematol , vol.81 , Issue.3 , pp. 325-330
    • Ward, C.S.1    Westwood, N.B.2    Emmerson, A.J.3    Pearson, T.C.4
  • 42
    • 0026011374 scopus 로고
    • The erythropoietic effects of interleukin 6 and erythropoietin in vivo
    • Ulich TR, del CJ, Yin SM, Egrie JC. The erythropoietic effects of interleukin 6 and erythropoietin in vivo. Exp Hematol. 1991;19(1):29-34.
    • (1991) Exp Hematol , vol.19 , Issue.1 , pp. 29-34
    • Ulich, T.R.1    Del, C.J.2    Yin, S.M.3    Egrie, J.C.4
  • 43
    • 79957586600 scopus 로고    scopus 로고
    • Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment
    • Singbrant S, Russell MR, Jovic T, et al. Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment. Blood. 2011;117(21):5631-5642.
    • (2011) Blood , vol.117 , Issue.21 , pp. 5631-5642
    • Singbrant, S.1    Russell, M.R.2    Jovic, T.3
  • 44
    • 0029912731 scopus 로고    scopus 로고
    • Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: Distinct interactions with the ligands for c-kit and FLT3
    • Ramsfjell V, Borge OJ, Veiby OP, et al. Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: distinct interactions with the ligands for c-kit and FLT3. Blood. 1996;88(12):4481-4492.
    • (1996) Blood , vol.88 , Issue.12 , pp. 4481-4492
    • Ramsfjell, V.1    Borge, O.J.2    Veiby, O.P.3
  • 45
    • 0037242691 scopus 로고    scopus 로고
    • Autocrine stimulation by erythropoietin in transgenic mice results in erythroid proliferation without neoplastic transformation
    • Madan A, Lin C, Wang Z, Curtin PT. Autocrine stimulation by erythropoietin in transgenic mice results in erythroid proliferation without neoplastic transformation. Blood Cells Mol Dis. 2003;30(1):82-89.
    • (2003) Blood Cells Mol Dis , vol.30 , Issue.1 , pp. 82-89
    • Madan, A.1    Lin, C.2    Wang, Z.3    Curtin, P.T.4
  • 46
    • 9844244548 scopus 로고    scopus 로고
    • Primary familial polycythaemia associated with a novel point mutation in the erythropoietin receptor
    • Furukawa T, Narita M, Sakaue M, et al. Primary familial polycythaemia associated with a novel point mutation in the erythropoietin receptor. Br J Haematol. 1997;99(1):222-227.
    • (1997) Br J Haematol , vol.99 , Issue.1 , pp. 222-227
    • Furukawa, T.1    Narita, M.2    Sakaue, M.3
  • 47
    • 0021646974 scopus 로고
    • The chemistry and physiology of erythropoietin
    • Sherwood JB. The chemistry and physiology of erythropoietin. Vitam Horm. 1984;41:161-211.
    • (1984) Vitam Horm , vol.41 , pp. 161-211
    • Sherwood, J.B.1
  • 48
    • 0026526168 scopus 로고
    • Erythropoietin: Structure, control of production, and function
    • Jelkmann W. Erythropoietin: structure, control of production, and function. Physiol Rev. 1992;72(2):449-489.
    • (1992) Physiol Rev , vol.72 , Issue.2 , pp. 449-489
    • Jelkmann, W.1
  • 50
    • 0027410945 scopus 로고
    • Co-localization of erythropoietin mRNA and ecto-5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin
    • Bachmann S, Le HM, Eckardt KU. Co-localization of erythropoietin mRNA and ecto-5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem. 1993;41(3):335-341.
    • (1993) J Histochem Cytochem , vol.41 , Issue.3 , pp. 335-341
    • Bachmann, S.1    Le, H.M.2    Eckardt, K.U.3
  • 51
    • 0027367661 scopus 로고
    • Identification of the renal erythropoietin-producing cells using transgenic mice
    • Maxwell PH, Osmond MK, Pugh CW, et al. Identification of the renal erythropoietin-producing cells using transgenic mice. Kidney Int. 1993; 44(5):1149-1162.
    • (1993) Kidney Int , vol.44 , Issue.5 , pp. 1149-1162
    • Maxwell, P.H.1    Osmond, M.K.2    Pugh, C.W.3
  • 52
    • 0025768277 scopus 로고
    • Organ distribution of erythropoietin messenger RNA in normal and uremic rats
    • Tan CC, Eckardt KU, Ratcliffe PJ. Organ distribution of erythropoietin messenger RNA in normal and uremic rats. Kidney Int. 1991;40(1):69-76.
    • (1991) Kidney Int , vol.40 , Issue.1 , pp. 69-76
    • Tan, C.C.1    Eckardt, K.U.2    Ratcliffe, P.J.3
  • 53
    • 0026072341 scopus 로고
    • Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice
    • Semenza GL, Koury ST, Nejfelt MK, Gearhart JD, Antonarakis SE. Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice. Proc Natl Acad Sci U S A. 1991;88(19):8725-8729.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.19 , pp. 8725-8729
    • Semenza, G.L.1    Koury, S.T.2    Nejfelt, M.K.3    Gearhart, J.D.4    Antonarakis, S.E.5
  • 54
    • 0027458517 scopus 로고
    • In vivo and in vitro regulation of erythropoietin mRNA: Measurement by competitive polymerase chain reaction
    • Fandrey J, Bunn HF. In vivo and in vitro regulation of erythropoietin mRNA: measurement by competitive polymerase chain reaction. Blood. 1993;81(3):617-623.
    • (1993) Blood , vol.81 , Issue.3 , pp. 617-623
    • Fandrey, J.1    Bunn, H.F.2
  • 55
    • 39749200886 scopus 로고    scopus 로고
    • Use of gene-manipulated mice in the study of erythropoietin gene expression
    • Suzuki N, Obara N, Yamamoto M. Use of gene-manipulated mice in the study of erythropoietin gene expression. Methods Enzymol. 2007;435:157-177.
    • (2007) Methods Enzymol , vol.435 , pp. 157-177
    • Suzuki, N.1    Obara, N.2    Yamamoto, M.3
  • 56
    • 0037169827 scopus 로고    scopus 로고
    • Quantitation of the mRNA levels of Epo and EpoR in various tissues in the ovine fetus
    • David RB, Lim GB, Moritz KM, Koukoulas I, Wintour EM. Quantitation of the mRNA levels of Epo and EpoR in various tissues in the ovine fetus. Mol Cell Endocrinol. 2002;188(1-2):207-218.
    • (2002) Mol Cell Endocrinol , vol.188 , Issue.1-2 , pp. 207-218
    • David, R.B.1    Lim, G.B.2    Moritz, K.M.3    Koukoulas, I.4    Wintour, E.M.5
  • 57
    • 0025892958 scopus 로고
    • Erythropoietin ontogeny and organ distribution in mice
    • Bondurant MC, Koury MJ, Koury ST, Semenza G. Erythropoietin ontogeny and organ distribution in mice. Semin Hematol. 1991;28(3 Suppl 3):20-25.
    • (1991) Semin Hematol , vol.28 , Issue.3 SUPPL 3 , pp. 20-25
    • Bondurant, M.C.1    Koury, M.J.2    Koury, S.T.3    Semenza, G.4
  • 58
    • 0018889403 scopus 로고
    • Renal and extrarenal erythropoietin production in anaemic rats
    • Erslev AJ, Caro J, Kansu E, Silver R. Renal and extrarenal erythropoietin production in anaemic rats. Br J Haematol. 1980;45(1):65-72.
    • (1980) Br J Haematol , vol.45 , Issue.1 , pp. 65-72
    • Erslev, A.J.1    Caro, J.2    Kansu, E.3    Silver, R.4
  • 59
    • 0022751115 scopus 로고
    • Anemia induces accumulation of erythropoietin mRNA in the kidney and liver
    • Bondurant MC, Koury MJ. Anemia induces accumulation of erythropoietin mRNA in the kidney and liver. Mol Cell Biol. 1986; 6(7):2731-2733.
    • (1986) Mol Cell Biol , vol.6 , Issue.7 , pp. 2731-2733
    • Bondurant, M.C.1    Koury, M.J.2
  • 60
    • 0026575755 scopus 로고
    • Age-dependent expression of the erythropoietin gene in rat liver and kidneys
    • Eckardt KU, Ratcliffe PJ, Tan CC, Bauer C, Kurtz A. Age-dependent expression of the erythropoietin gene in rat liver and kidneys. J Clin Invest. 1992;89(3):753-760.
    • (1992) J Clin Invest , vol.89 , Issue.3 , pp. 753-760
    • Eckardt, K.U.1    Ratcliffe, P.J.2    Tan, C.C.3    Bauer, C.4    Kurtz, A.5
  • 61
    • 0025912710 scopus 로고
    • Localization of cells producing erythropoietin in murine liver by in situ hybridization
    • Koury ST, Bondurant MC, Koury MJ, Semenza GL. Localization of cells producing erythropoietin in murine liver by in situ hybridization. Blood. 1991;77(11):2497-2503.
    • (1991) Blood , vol.77 , Issue.11 , pp. 2497-2503
    • Koury, S.T.1    Bondurant, M.C.2    Koury, M.J.3    Semenza, G.L.4
  • 62
    • 79955963946 scopus 로고    scopus 로고
    • Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC
    • Frede S, Freitag P, Geuting L, Konietzny R, Fandrey J. Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC. Blood. 2011;117(18):4905-4914.
    • (2011) Blood , vol.117 , Issue.18 , pp. 4905-4914
    • Frede, S.1    Freitag, P.2    Geuting, L.3    Konietzny, R.4    Fandrey, J.5
  • 63
    • 0027935351 scopus 로고
    • Transgenic mice carrying the erythropoietin gene promoter linked to lacZ express the reporter in proximal convoluted tubule cells after hypoxia
    • Loya F, Yang Y, Lin H, Goldwasser E, Albitar M. Transgenic mice carrying the erythropoietin gene promoter linked to lacZ express the reporter in proximal convoluted tubule cells after hypoxia. Blood. 1994;84(6):1831-1836.
    • (1994) Blood , vol.84 , Issue.6 , pp. 1831-1836
    • Loya, F.1    Yang, Y.2    Lin, H.3    Goldwasser, E.4    Albitar, M.5
  • 64
    • 36849059273 scopus 로고    scopus 로고
    • Characterization of erythropoietin receptor and erythropoietin expression and function in human ovarian cancer cells
    • Jeong JY, Feldman L, Solar P, Szenajch J, Sytkowski AJ. Characterization of erythropoietin receptor and erythropoietin expression and function in human ovarian cancer cells. Int J Cancer. 2008;122(2):274-280.
    • (2008) Int J Cancer , vol.122 , Issue.2 , pp. 274-280
    • Jeong, J.Y.1    Feldman, L.2    Solar, P.3    Szenajch, J.4    Sytkowski, A.J.5
  • 65
    • 67651155966 scopus 로고    scopus 로고
    • An erythropoietin autocrine/paracrine axis modulates the growth and survival of human prostate cancer cells
    • Jeong JY, Hoxhaj G, Socha AL, Sytkowski AJ, Feldman L. An erythropoietin autocrine/paracrine axis modulates the growth and survival of human prostate cancer cells. Mol Cancer Res. 2009;7(7):1150-1157.
    • (2009) Mol Cancer Res , vol.7 , Issue.7 , pp. 1150-1157
    • Jeong, J.Y.1    Hoxhaj, G.2    Socha, A.L.3    Sytkowski, A.J.4    Feldman, L.5
  • 66
    • 0036720851 scopus 로고    scopus 로고
    • Immunohistochemical expression of erythropoietin and erythropoietin receptor in breast carcinoma
    • Acs G, Zhang PJ, Rebbeck TR, Acs P, Verma A. Immunohistochemical expression of erythropoietin and erythropoietin receptor in breast carcinoma. Cancer. 2002;95(5):969-981.
    • (2002) Cancer , vol.95 , Issue.5 , pp. 969-981
    • Acs, G.1    Zhang, P.J.2    Rebbeck, T.R.3    Acs, P.4    Verma, A.5
  • 67
    • 79959236919 scopus 로고    scopus 로고
    • Expression of erythropoietin and its receptor increases in colonic neoplastic progression: The role of hypoxia in tumorigenesis
    • Gombos Z, Danihel L, Repiska V, Acs G, Furth E. Expression of erythropoietin and its receptor increases in colonic neoplastic progression: the role of hypoxia in tumorigenesis. Indian J Pathol Microbiol. 2011;54(2):273-278.
    • (2011) Indian J Pathol Microbiol , vol.54 , Issue.2 , pp. 273-278
    • Gombos, Z.1    Danihel, L.2    Repiska, V.3    Acs, G.4    Furth, E.5
  • 68
    • 65649093029 scopus 로고    scopus 로고
    • Erythropoietin receptor expression is concordant with erythropoietin but not with common beta chain expression in the rat brain throughout the life span
    • Sanchez PE, Navarro FP, Fares RP, et al. Erythropoietin receptor expression is concordant with erythropoietin but not with common beta chain expression in the rat brain throughout the life span. J Comp Neurol. 2009;514(4):403-414.
    • (2009) J Comp Neurol , vol.514 , Issue.4 , pp. 403-414
    • Sanchez, P.E.1    Navarro, F.P.2    Fares, R.P.3
  • 69
    • 23244447252 scopus 로고    scopus 로고
    • Expression of erythropoietin and its receptor in the brain of late-gestation fetal sheep, and responses to asphyxia caused by umbilical cord occlusion
    • Castillo-Melendez M, Yan E, Walker DW. Expression of erythropoietin and its receptor in the brain of late-gestation fetal sheep, and responses to asphyxia caused by umbilical cord occlusion. Dev Neurosci. 2005;27(2-4):220-227.
    • (2005) Dev Neurosci , vol.27 , Issue.2-4 , pp. 220-227
    • Castillo-Melendez, M.1    Yan, E.2    Walker, D.W.3
  • 70
    • 3242733091 scopus 로고    scopus 로고
    • Age-related changes in erythropoietin immunoreactivity in the cerebral cortex and hippocampus of rats
    • Chung YH, Kim SI, Joo KM, et al. Age-related changes in erythropoietin immunoreactivity in the cerebral cortex and hippocampus of rats. Brain Res. 2004;1018(1):141-146.
    • (2004) Brain Res , vol.1018 , Issue.1 , pp. 141-146
    • Chung, Y.H.1    Kim, S.I.2    Joo, K.M.3
  • 71
    • 1642393656 scopus 로고    scopus 로고
    • Expression patterns of erythropoietin and its receptor in the developing midbrain
    • Knabe W, Knerlich F, Washausen S, et al. Expression patterns of erythropoietin and its receptor in the developing midbrain. Anat Embryol (Berl). 2004;207(6):503-512.
    • (2004) Anat Embryol (Berl) , vol.207 , Issue.6 , pp. 503-512
    • Knabe, W.1    Knerlich, F.2    Washausen, S.3
  • 72
    • 0025328797 scopus 로고
    • The gene for the human erythropoietin receptor: Analysis of the coding sequence and assignment to chromosome 19p
    • Winkelmann JC, Penny LA, Deaven LL, Forget BG, Jenkins RB. The gene for the human erythropoietin receptor: analysis of the coding sequence and assignment to chromosome 19p. Blood. 1990;76(1):24-30.
    • (1990) Blood , vol.76 , Issue.1 , pp. 24-30
    • Winkelmann, J.C.1    Penny, L.A.2    Deaven, L.L.3    Forget, B.G.4    Jenkins, R.B.5
  • 73
    • 0025337049 scopus 로고
    • Human erythropoietin receptor: Cloning, expression, and biologic characterization
    • Jones SS, D'Andrea AD, Haines LL, Wong GG. Human erythropoietin receptor: cloning, expression, and biologic characterization. Blood. 1990;76(1):31-35.
    • (1990) Blood , vol.76 , Issue.1 , pp. 31-35
    • Jones, S.S.1    D'Andrea, A.D.2    Haines, L.L.3    Wong, G.G.4
  • 74
    • 0024563574 scopus 로고
    • Expression cloning of the murine erythropoietin receptor
    • D'Andrea AD, Lodish HF, Wong GG. Expression cloning of the murine erythropoietin receptor. Cell. 1989;57(2):277-285.
    • (1989) Cell , vol.57 , Issue.2 , pp. 277-285
    • D'Andrea, A.D.1    Lodish, H.F.2    Wong, G.G.3
  • 75
    • 0025242756 scopus 로고
    • Assignment of the erythropoietin receptor (EPOR) gene to mouse chromosome 9 and human chromosome 19
    • Budarf M, Huebner K, Emanuel B, et al. Assignment of the erythropoietin receptor (EPOR) gene to mouse chromosome 9 and human chromosome 19. Genomics. 1990;8(3):575-578.
    • (1990) Genomics , vol.8 , Issue.3 , pp. 575-578
    • Budarf, M.1    Huebner, K.2    Emanuel, B.3
  • 76
    • 33344461329 scopus 로고    scopus 로고
    • Anti-Epo receptor antibodies do not predict Epo receptor expression
    • Elliott S, Busse L, Bass MB, et al. Anti-Epo receptor antibodies do not predict Epo receptor expression. Blood. 2006;107(5):1892-1895.
    • (2006) Blood , vol.107 , Issue.5 , pp. 1892-1895
    • Elliott, S.1    Busse, L.2    Bass, M.B.3
  • 77
    • 0025914989 scopus 로고
    • Characterization of the structure of the erythropoietin receptor by ligand blotting
    • Atkins HL, Broudy VC, Papayannopoulou T. Characterization of the structure of the erythropoietin receptor by ligand blotting. Blood. 1991;77(12):2577-2582.
    • (1991) Blood , vol.77 , Issue.12 , pp. 2577-2582
    • Atkins, H.L.1    Broudy, V.C.2    Papayannopoulou, T.3
  • 78
    • 71749103027 scopus 로고    scopus 로고
    • Identification of a sensitive anti-erythropoietin receptor monoclonal antibody allows detection of low levels of EpoR in cells
    • Elliott S, Busse L, McCaffery I, et al. Identification of a sensitive anti-erythropoietin receptor monoclonal antibody allows detection of low levels of EpoR in cells. J Immunol Methods. 2010;352:126-139.
    • (2010) J Immunol Methods , vol.352 , pp. 126-139
    • Elliott, S.1    Busse, L.2    McCaffery, I.3
  • 79
    • 0037135530 scopus 로고    scopus 로고
    • A functional green fluorescent protein-erythropoietin receptor despite physical separation of JAK2 binding site and tyrosine residues
    • Ketteler R, Heinrich AC, Offe JK, et al. A functional green fluorescent protein-erythropoietin receptor despite physical separation of JAK2 binding site and tyrosine residues. J Biol Chem. 2002; 277(29):26547-26552.
    • (2002) J Biol Chem , vol.277 , Issue.29 , pp. 26547-26552
    • Ketteler, R.1    Heinrich, A.C.2    Offe, J.K.3
  • 80
    • 77953629597 scopus 로고    scopus 로고
    • Absence of functional EpoR expression in human tumor cell lines
    • Swift S, Ellison AR, Kassner P, et al. Absence of functional EpoR expression in human tumor cell lines. Blood. 2010;115(21):4254-4263.
    • (2010) Blood , vol.115 , Issue.21 , pp. 4254-4263
    • Swift, S.1    Ellison, A.R.2    Kassner, P.3
  • 81
    • 0027379586 scopus 로고
    • Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes
    • Neumann D, Wikstrom L, Watowich SS, Lodish HF. Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes. J Biol Chem. 1993;268(18):13639-13649.
    • (1993) J Biol Chem , vol.268 , Issue.18 , pp. 13639-13649
    • Neumann, D.1    Wikstrom, L.2    Watowich, S.S.3    Lodish, H.F.4
  • 82
    • 0028963213 scopus 로고
    • Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor
    • Hilton DJ, Watowich SS, Murray PJ, Lodish HF. Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor. Proc Natl Acad Sci U S A. 1995;92(1):190-194.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.1 , pp. 190-194
    • Hilton, D.J.1    Watowich, S.S.2    Murray, P.J.3    Lodish, H.F.4
  • 83
    • 0000311479 scopus 로고    scopus 로고
    • A cytosolic domain of the erythropoietin receptor contributes to endoplasmic reticulum-associated degradation
    • Supino-Rosin L, Yoshimura A, Altaratz H, Neumann D. A cytosolic domain of the erythropoietin receptor contributes to endoplasmic reticulum-associated degradation. Eur J Biochem. 1999;263(2):410-419.
    • (1999) Eur J Biochem , vol.263 , Issue.2 , pp. 410-419
    • Supino-Rosin, L.1    Yoshimura, A.2    Altaratz, H.3    Neumann, D.4
  • 84
    • 0035871810 scopus 로고    scopus 로고
    • Resolution of pluripotential intermediates in murine hematopoietic differentiation by global complementary DNA amplification from single cells: Confirmation of assignments by expression profiling of cytokine receptor transcripts
    • Billia F, Barbara M, McEwen J, Trevisan M, Iscove NN. Resolution of pluripotential intermediates in murine hematopoietic differentiation by global complementary DNA amplification from single cells: confirmation of assignments by expression profiling of cytokine receptor transcripts. Blood. 2001;97(8):2257-2268.
    • (2001) Blood , vol.97 , Issue.8 , pp. 2257-2268
    • Billia, F.1    Barbara, M.2    McEwen, J.3    Trevisan, M.4    Iscove, N.N.5
  • 85
    • 0028072274 scopus 로고
    • Tissue specific expression of human erythropoietin receptor in transgenic mice
    • Liu ZY, Chin K, Noguchi CT. Tissue specific expression of human erythropoietin receptor in transgenic mice. Dev Biol. 1994; 166(1):159-169.
    • (1994) Dev Biol , vol.166 , Issue.1 , pp. 159-169
    • Liu, Z.Y.1    Chin, K.2    Noguchi, C.T.3
  • 86
    • 0025914297 scopus 로고
    • GATA-1 transactivates erythropoietin receptor gene, and erythropoietin receptor-mediated signals enhance GATA-1 gene expression
    • Chiba T, Ikawa Y, Todokoro K. GATA-1 transactivates erythropoietin receptor gene, and erythropoietin receptor-mediated signals enhance GATA-1 gene expression. Nucleic Acids Res. 1991;19(14):3843-3848.
    • (1991) Nucleic Acids Res , vol.19 , Issue.14 , pp. 3843-3848
    • Chiba, T.1    Ikawa, Y.2    Todokoro, K.3
  • 87
    • 0026552539 scopus 로고
    • The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: Evidence for differentiation stage-specific regulation
    • Heberlein C, Fischer KD, Stoffel M, et al. The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation. Mol Cell Biol. 1992;12(4):1815-1826.
    • (1992) Mol Cell Biol , vol.12 , Issue.4 , pp. 1815-1826
    • Heberlein, C.1    Fischer, K.D.2    Stoffel, M.3
  • 88
    • 3242807457 scopus 로고    scopus 로고
    • A mouse model for visualization and conditional mutations in the erythroid lineage
    • Heinrich AC, Pelanda R, Klingmuller U. A mouse model for visualization and conditional mutations in the erythroid lineage. Blood. 2004;104(3):659-666.
    • (2004) Blood , vol.104 , Issue.3 , pp. 659-666
    • Heinrich, A.C.1    Pelanda, R.2    Klingmuller, U.3
  • 89
    • 0031010549 scopus 로고    scopus 로고
    • Growth factor receptor expression during in vitro differentiation of partially purified populations containing murine stem cells
    • Ashihara E, Vannucchi AM, Migliaccio G, Migliaccio AR. Growth factor receptor expression during in vitro differentiation of partially purified populations containing murine stem cells. J Cell Physiol. 1997;171(3):343-356.
    • (1997) J Cell Physiol , vol.171 , Issue.3 , pp. 343-356
    • Ashihara, E.1    Vannucchi, A.M.2    Migliaccio, G.3    Migliaccio, A.R.4
  • 90
    • 0031010122 scopus 로고    scopus 로고
    • Selective expression of mRNA coding for the truncated form of erythropoietin receptor in hematopoietic cells and its decrease in patients with polycythemia vera
    • Chiba S, Takahashi T, Takeshita K, et al. Selective expression of mRNA coding for the truncated form of erythropoietin receptor in hematopoietic cells and its decrease in patients with polycythemia vera. Blood. 1997;90(1):97-104.
    • (1997) Blood , vol.90 , Issue.1 , pp. 97-104
    • Chiba, S.1    Takahashi, T.2    Takeshita, K.3
  • 91
    • 38749126795 scopus 로고    scopus 로고
    • Lack of functional erythropoietin receptors of cancer cell lines
    • Laugsch M, Metzen E, Svensson T, Depping R, Jelkmann W. Lack of functional erythropoietin receptors of cancer cell lines. Int J Cancer. 2008;122(5):1005-1011.
    • (2008) Int J Cancer , vol.122 , Issue.5 , pp. 1005-1011
    • Laugsch, M.1    Metzen, E.2    Svensson, T.3    Depping, R.4    Jelkmann, W.5
  • 92
    • 40849137929 scopus 로고    scopus 로고
    • Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells
    • Sinclair AM, Rogers N, Busse L, et al. Erythropoietin receptor transcription is neither elevated nor predictive of surface expression in human tumour cells. Br J Cancer. 2008;98(6):1059-1067.
    • (2008) Br J Cancer , vol.98 , Issue.6 , pp. 1059-1067
    • Sinclair, A.M.1    Rogers, N.2    Busse, L.3
  • 93
    • 34248187723 scopus 로고    scopus 로고
    • Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators
    • Keller MA, Addya S, Vadigepalli R, et al. Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators. Physiol Genomics. 2006;28(1):114-128.
    • (2006) Physiol Genomics , vol.28 , Issue.1 , pp. 114-128
    • Keller, M.A.1    Addya, S.2    Vadigepalli, R.3
  • 94
    • 77952172809 scopus 로고    scopus 로고
    • Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells
    • Sinclair AM, Coxon A, McCaffery I, et al. Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells. Blood. 2010;115(21):4264-4272.
    • (2010) Blood , vol.115 , Issue.21 , pp. 4264-4272
    • Sinclair, A.M.1    Coxon, A.2    McCaffery, I.3
  • 96
    • 34250710896 scopus 로고    scopus 로고
    • Expression of erythropoietin receptor and in vitro functional effects of epoetins in B-cell malignancies
    • Kokhaei P, Abdalla AO, Hansson L, et al. Expression of erythropoietin receptor and in vitro functional effects of epoetins in B-cell malignancies. Clin Cancer Res. 2007;13(12):3536-3544.
    • (2007) Clin Cancer Res , vol.13 , Issue.12 , pp. 3536-3544
    • Kokhaei, P.1    Abdalla, A.O.2    Hansson, L.3
  • 97
    • 33847615316 scopus 로고    scopus 로고
    • Erythropoietin receptor expression in non-small cell lung carcinoma: A question of antibody specificity
    • Brown WM, Maxwell P, Graham AN, et al. Erythropoietin receptor expression in non-small cell lung carcinoma: a question of antibody specificity. Stem Cells. 2007;25(3):718-722.
    • (2007) Stem Cells , vol.25 , Issue.3 , pp. 718-722
    • Brown, W.M.1    Maxwell, P.2    Graham, A.N.3
  • 98
    • 34250622423 scopus 로고    scopus 로고
    • Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor
    • Kirkeby A, van BJ, Nielsen J, Leist M, Helboe L. Functional and immunochemical characterisation of different antibodies against the erythropoietin receptor. J Neurosci Methods. 2007;164(1):50-58.
    • (2007) J Neurosci Methods , vol.164 , Issue.1 , pp. 50-58
    • Kirkeby, A.1    Van, B.J.2    Nielsen, J.3    Leist, M.4    Helboe, L.5
  • 99
    • 34547120946 scopus 로고    scopus 로고
    • Expression and function of erythropoietin receptors in tumors: Implications for the use of erythropoiesis-stimulating agents in cancer patients
    • Sinclair AM, Todd MD, Forsythe K, Knox SJ, Elliott S, Begley CG. Expression and function of erythropoietin receptors in tumors: implications for the use of erythropoiesis-stimulating agents in cancer patients. Cancer. 2007;110(3):477-488.
    • (2007) Cancer , vol.110 , Issue.3 , pp. 477-488
    • Sinclair, A.M.1    Todd, M.D.2    Forsythe, K.3    Knox, S.J.4    Elliott, S.5    Begley, C.G.6
  • 100
    • 33846615414 scopus 로고    scopus 로고
    • Preclinical studies of erythropoietin receptor expression in tumour cells: Impact on clinical use of erythropoietic proteins to correct cancer-related anaemia
    • Osterborg A, Aapro M, Cornes P, Haselbeck A, Hayward CR, Jelkmann W. Preclinical studies of erythropoietin receptor expression in tumour cells: impact on clinical use of erythropoietic proteins to correct cancer-related anaemia. Eur J Cancer. 2007;43(3):510-519.
    • (2007) Eur J Cancer , vol.43 , Issue.3 , pp. 510-519
    • Osterborg, A.1    Aapro, M.2    Cornes, P.3    Haselbeck, A.4    Hayward, C.R.5    Jelkmann, W.6
  • 101
    • 65249172477 scopus 로고    scopus 로고
    • Specificity concerns with antibodies for receptor mapping
    • Kirkpatrick P. Specificity concerns with antibodies for receptor mapping. Nat Rev Drug Discov. 2009;8(4):278.
    • (2009) Nat Rev Drug Discov , vol.8 , Issue.4 , pp. 278
    • Kirkpatrick, P.1
  • 103
    • 0023814390 scopus 로고
    • Identification of the receptor for erythropoietin on human and murine erythroleukemia cells and modulation by phorbol ester and dimethyl sulfoxide
    • Broudy VC, Lin N, Egrie J, et al. Identification of the receptor for erythropoietin on human and murine erythroleukemia cells and modulation by phorbol ester and dimethyl sulfoxide. Proc Natl Acad Sci U S A. 1988;85(17):6513-6517.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , Issue.17 , pp. 6513-6517
    • Broudy, V.C.1    Lin, N.2    Egrie, J.3
  • 104
    • 0025908919 scopus 로고
    • Erythropoietin receptor characteristics on primary human erythroid cells
    • Broudy VC, Lin N, Brice M, Nakamoto B, Papayannopoulou T. Erythropoietin receptor characteristics on primary human erythroid cells. Blood. 1991;77(12):2583-2590.
    • (1991) Blood , vol.77 , Issue.12 , pp. 2583-2590
    • Broudy, V.C.1    Lin, N.2    Brice, M.3    Nakamoto, B.4    Papayannopoulou, T.5
  • 105
    • 0028960781 scopus 로고
    • Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells
    • Radinsky R, Risin S, Fan D, et al. Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells. Clin Cancer Res. 1995;1(1):19-31.
    • (1995) Clin Cancer Res , vol.1 , Issue.1 , pp. 19-31
    • Radinsky, R.1    Risin, S.2    Fan, D.3
  • 106
    • 10744221013 scopus 로고    scopus 로고
    • Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody
    • Foon KA, Yang XD, Weiner LM, et al. Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody. Int J Radiat Oncol Biol Phys. 2004;58(3):984-990.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , Issue.3 , pp. 984-990
    • Foon, K.A.1    Yang, X.D.2    Weiner, L.M.3
  • 107
    • 0023432159 scopus 로고
    • Characterization of erythropoietin receptor of murine erythroid cells
    • Sasaki R, Yanagawa S, Hitomi K, Chiba H. Characterization of erythropoietin receptor of murine erythroid cells. Eur J Biochem. 1987;168(1):43-48.
    • (1987) Eur J Biochem , vol.168 , Issue.1 , pp. 43-48
    • Sasaki, R.1    Yanagawa, S.2    Hitomi, K.3    Chiba, H.4
  • 108
    • 0029014672 scopus 로고
    • Lineage-restricted recruitment of immature hematopoietic progenitor cells in response to Epo after normal hematopoietic cell transfection with EpoR
    • McArthur GA, Longmore GD, Klingler K, Johnson GR. Lineage-restricted recruitment of immature hematopoietic progenitor cells in response to Epo after normal hematopoietic cell transfection with EpoR. Exp Hematol. 1995;23(7):645-654.
    • (1995) Exp Hematol , vol.23 , Issue.7 , pp. 645-654
    • McArthur, G.A.1    Longmore, G.D.2    Klingler, K.3    Johnson, G.R.4
  • 109
    • 0024209087 scopus 로고
    • Quantitation of specific binding of erythropoietin to human erythroid colony-forming cells
    • Sawada K, Krantz SB, Sawyer ST, Civin CI. Quantitation of specific binding of erythropoietin to human erythroid colony-forming cells. J Cell Physiol. 1988;137(2):337-345.
    • (1988) J Cell Physiol , vol.137 , Issue.2 , pp. 337-345
    • Sawada, K.1    Krantz, S.B.2    Sawyer, S.T.3    Civin, C.I.4
  • 110
    • 0025144329 scopus 로고
    • Detection and isolation of the erythropoietin receptor using biotinylated erythropoietin
    • Wognum AW, Lansdorp PM, Humphries RK, Krystal G. Detection and isolation of the erythropoietin receptor using biotinylated erythropoietin. Blood. 1990;76(4):697-705.
    • (1990) Blood , vol.76 , Issue.4 , pp. 697-705
    • Wognum, A.W.1    Lansdorp, P.M.2    Humphries, R.K.3    Krystal, G.4
  • 111
    • 0026530736 scopus 로고
    • Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia
    • Wognum AW, Krystal G, Eaves CJ, Eaves AC, Lansdorp PM. Increased erythropoietin-receptor expression on CD34-positive bone marrow cells from patients with chronic myeloid leukemia. Blood. 1992;79(3):642-649.
    • (1992) Blood , vol.79 , Issue.3 , pp. 642-649
    • Wognum, A.W.1    Krystal, G.2    Eaves, C.J.3    Eaves, A.C.4    Lansdorp, P.M.5
  • 112
    • 0031038174 scopus 로고    scopus 로고
    • Erythropoietin receptor expression on human bone marrow erythroid precursor cells by a newly-devised quantitative flow-cytometric assay
    • Shinjo K, Takeshita A, Higuchi M, Ohnishi K, Ohno R. Erythropoietin receptor expression on human bone marrow erythroid precursor cells by a newly-devised quantitative flow-cytometric assay. Br J Haematol. 1997;96(3):551-558.
    • (1997) Br J Haematol , vol.96 , Issue.3 , pp. 551-558
    • Shinjo, K.1    Takeshita, A.2    Higuchi, M.3    Ohnishi, K.4    Ohno, R.5
  • 113
    • 0023656554 scopus 로고
    • The erythropoietin receptor of rat erythroid progenitor cells. Characterization and affinity cross-linkage
    • Mayeux P, Billat C, Jacquot R. The erythropoietin receptor of rat erythroid progenitor cells. Characterization and affinity cross-linkage. J Biol Chem. 1987;262(29):13985-13990.
    • (1987) J Biol Chem , vol.262 , Issue.29 , pp. 13985-13990
    • Mayeux, P.1    Billat, C.2    Jacquot, R.3
  • 114
    • 0024556997 scopus 로고
    • Expression and characterization of erythropoietin receptors on normal human bone marrow cells
    • Hoshino S, Teramura M, Takahashi M, et al. Expression and characterization of erythropoietin receptors on normal human bone marrow cells. Int J Cell Cloning. 1989;7(3):156-167.
    • (1989) Int J Cell Cloning , vol.7 , Issue.3 , pp. 156-167
    • Hoshino, S.1    Teramura, M.2    Takahashi, M.3
  • 115
    • 0023700208 scopus 로고
    • Expression of high affinity receptors for erythropoietin on human bone marrow cells and on the human erythroleukemic cell line
    • Fraser JK, Lin FK, Berridge MV. Expression of high affinity receptors for erythropoietin on human bone marrow cells and on the human erythroleukemic cell line, HEL. Exp Hematol. 1988;16(10):836-842.
    • (1988) HEL. Exp Hematol , vol.16 , Issue.10 , pp. 836-842
    • Fraser, J.K.1    Lin, F.K.2    Berridge, M.V.3
  • 116
    • 0028880455 scopus 로고
    • Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
    • Wu H, Liu X, Jaenisch R, Lodish HF. Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell. 1995;83(1):59-67.
    • (1995) Cell , vol.83 , Issue.1 , pp. 59-67
    • Wu, H.1    Liu, X.2    Jaenisch, R.3    Lodish, H.F.4
  • 117
    • 0024512470 scopus 로고
    • Effects of five recombinant hematopoietic growth factors on enriched human erythroid progenitors in serum-replaced cultures
    • Mitjavila MT, Natazawa M, Brignaschi P, Debili N, Breton-Gorius J, Vainchenker W. Effects of five recombinant hematopoietic growth factors on enriched human erythroid progenitors in serum-replaced cultures. J Cell Physiol. 1989;138(3):617-623.
    • (1989) J Cell Physiol , vol.138 , Issue.3 , pp. 617-623
    • Mitjavila, M.T.1    Natazawa, M.2    Brignaschi, P.3    Debili, N.4    Breton-Gorius, J.5    Vainchenker, W.6
  • 118
    • 0038478287 scopus 로고    scopus 로고
    • Dominant action of mutated erythropoietin receptors on differentiation in vitro and erythroleukemia development in vivo
    • Cull V, Tilbrook PA, Adenan AS. Dominant action of mutated erythropoietin receptors on differentiation in vitro and erythroleukemia development in vivo. Oncogene. 2000;19(7):953-960.
    • (2000) Oncogene , vol.19 , Issue.7 , pp. 953-960
    • Cull, V.1    Tilbrook, P.A.2    Adenan, A.S.3
  • 119
    • 0035694582 scopus 로고    scopus 로고
    • The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor
    • Huang LJ, Constantinescu SN, Lodish HF. The N-terminal domain of Janus kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor. Mol Cell. 2001;8(6):1327-1338.
    • (2001) Mol Cell , vol.8 , Issue.6 , pp. 1327-1338
    • Huang, L.J.1    Constantinescu, S.N.2    Lodish, H.F.3
  • 120
    • 0026009698 scopus 로고
    • Abundance and stability of erythropoietin receptor mRNA in mouse erythroid progenitor cells
    • Wickrema A, Bondurant MC, Krantz SB. Abundance and stability of erythropoietin receptor mRNA in mouse erythroid progenitor cells. Blood. 1991;78(9):2269-2275.
    • (1991) Blood , vol.78 , Issue.9 , pp. 2269-2275
    • Wickrema, A.1    Bondurant, M.C.2    Krantz, S.B.3
  • 123
    • 0025786584 scopus 로고
    • Activation of the erythropoietin receptor promoter by transcription factor GATA-1
    • Zon LI, Youssoufian H, Mather C, Lodish HF, Orkin SH. Activation of the erythropoietin receptor promoter by transcription factor GATA-1. Proc Natl Acad Sci U S A. 1991;88(23):10638-10641.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.23 , pp. 10638-10641
    • Zon, L.I.1    Youssoufian, H.2    Mather, C.3    Lodish, H.F.4    Orkin, S.H.5
  • 124
    • 0028285242 scopus 로고
    • Different domains regulate the human erythropoietin receptor gene transcription
    • Maouche L, Cartron JP, Chretien S. Different domains regulate the human erythropoietin receptor gene transcription. Nucleic Acids Res. 1994;22(3):338-346.
    • (1994) Nucleic Acids Res , vol.22 , Issue.3 , pp. 338-346
    • Maouche, L.1    Cartron, J.P.2    Chretien, S.3
  • 125
    • 0028006280 scopus 로고
    • Further characterization of cis-acting regulatory sequences in the genomic locus of the murine erythropoietin receptor: Evidence for stage-specific regulation
    • Youssoufian H. Further characterization of cis-acting regulatory sequences in the genomic locus of the murine erythropoietin receptor: evidence for stage-specific regulation. Blood. 1994;83(5):1428-1435.
    • (1994) Blood , vol.83 , Issue.5 , pp. 1428-1435
    • Youssoufian, H.1
  • 126
    • 0025606357 scopus 로고
    • Characterization of murine erythropoietin receptor genes
    • Kuramochi S, Ikawa Y, Todokoro K. Characterization of murine erythropoietin receptor genes. J Mol Biol. 1990;216(3):567-575.
    • (1990) J Mol Biol , vol.216 , Issue.3 , pp. 567-575
    • Kuramochi, S.1    Ikawa, Y.2    Todokoro, K.3
  • 127
    • 79957586600 scopus 로고    scopus 로고
    • Erythropoietin couples erythropoiesis, B lymphopoiesis, and bone homeostasis within the bone marrow microenvironment
    • Singbrant S, Russell MR, Jovic, et al. Erythropoietin couples erythropoiesis, B lymphopoiesis, and bone homeostasis within the bone marrow microenvironment. Blood. 2011;117(21):5631-5642.
    • (2011) Blood , vol.117 , Issue.21 , pp. 5631-5642
    • Singbrant, S.1    Russell, M.R.2    Jovic3
  • 128
    • 77952483216 scopus 로고    scopus 로고
    • Epo is relevant neither for microvascular formation nor for the new formation and maintenance of mice skeletal muscle fibres in both normoxia and hypoxia
    • 137817
    • Hagstrom L, Agbulut O, El-Hasnaoui-Saadani R, et al. Epo is relevant neither for microvascular formation nor for the new formation and maintenance of mice skeletal muscle fibres in both normoxia and hypoxia. J Biomed Biotechnol. 2010;2010:137817.
    • (2010) J Biomed Biotechnol , pp. 2010
    • Hagstrom, L.1    Agbulut, O.2    El-Hasnaoui-Saadani, R.3
  • 129
    • 0034068673 scopus 로고    scopus 로고
    • Exposure of endothelial cells to recombinant human erythropoietin induces nitric oxide synthase activity
    • Banerjee D, Rodriguez M, Nag M, Adamson JW. Exposure of endothelial cells to recombinant human erythropoietin induces nitric oxide synthase activity. Kidney Int. 2000;57(5):1895-1904.
    • (2000) Kidney Int , vol.57 , Issue.5 , pp. 1895-1904
    • Banerjee, D.1    Rodriguez, M.2    Nag, M.3    Adamson, J.W.4
  • 130
    • 15844364757 scopus 로고    scopus 로고
    • Autocrine regulation of erythropoietin gene expression in human hepatocellular carcinoma cells
    • Ohigashi T, Yoshioka K, Fisher JW. Autocrine regulation of erythropoietin gene expression in human hepatocellular carcinoma cells. Life Sci. 1996;58(5):421-427.
    • (1996) Life Sci , vol.58 , Issue.5 , pp. 421-427
    • Ohigashi, T.1    Yoshioka, K.2    Fisher, J.W.3
  • 131
    • 0029007084 scopus 로고
    • Localization of specific erythropoietin binding sites in defined areas of the mouse brain
    • Digicaylioglu M, Bichet S, Marti HH, et al. Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proc Natl Acad Sci U S A. 1995;92(9):3717-3720.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.9 , pp. 3717-3720
    • Digicaylioglu, M.1    Bichet, S.2    Marti, H.H.3
  • 132
    • 33846844805 scopus 로고    scopus 로고
    • Survival and invasiveness of astrocytomas promoted by erythropoietin
    • Mohyeldin A, Dalgard CL, Lu H, et al. Survival and invasiveness of astrocytomas promoted by erythropoietin. J Neurosurg. 2007;106(2): 338-350.
    • (2007) J Neurosurg , vol.106 , Issue.2 , pp. 338-350
    • Mohyeldin, A.1    Dalgard, C.L.2    Lu, H.3
  • 133
    • 65649135886 scopus 로고    scopus 로고
    • No evidence for protective erythropoietin alpha signalling in rat hepatocytes
    • Bramey T, Freitag P, Fandrey J, et al. No evidence for protective erythropoietin alpha signalling in rat hepatocytes. BMC Gastroenterol. 2009;9:26.
    • (2009) BMC Gastroenterol , vol.9 , pp. 26
    • Bramey, T.1    Freitag, P.2    Fandrey, J.3
  • 134
    • 27744480301 scopus 로고    scopus 로고
    • Relation of erythropoietin and erythropoietin receptor expression to hypoxia and anemia in head and neck squamous cell carcinoma
    • Winter SC, Shah KA, Campo L, et al. Relation of erythropoietin and erythropoietin receptor expression to hypoxia and anemia in head and neck squamous cell carcinoma. Clin Cancer Res. 2005;11(21): 7614-7620.
    • (2005) Clin Cancer Res , vol.11 , Issue.21 , pp. 7614-7620
    • Winter, S.C.1    Shah, K.A.2    Campo, L.3
  • 135
    • 0034013854 scopus 로고    scopus 로고
    • Neurons and astrocytes express EPO mRNA: Oxygen-sensing mechanisms that involve the redox-state of the brain
    • Bernaudin M, Bellail A, Marti HH, et al. Neurons and astrocytes express EPO mRNA: oxygen-sensing mechanisms that involve the redox-state of the brain. Glia. 2000;30(3):271-278.
    • (2000) Glia , vol.30 , Issue.3 , pp. 271-278
    • Bernaudin, M.1    Bellail, A.2    Marti, H.H.3
  • 136
    • 77149144493 scopus 로고    scopus 로고
    • STAT3 and hypoxia induced proteins - HIF-1alpha, EPO and EPOR in relation with Bax and Bcl-xL in nodal metastases of ductal breast cancers
    • Wincewicz A, Koda M, Sulkowska M, Kanczuga-Koda L, Wincewicz D, Sulkowski S. STAT3 and hypoxia induced proteins - HIF-1alpha, EPO and EPOR in relation with Bax and Bcl-xL in nodal metastases of ductal breast cancers. Folia Histochem Cytobiol. 2009;47(3):425-430.
    • (2009) Folia Histochem Cytobiol , vol.47 , Issue.3 , pp. 425-430
    • Wincewicz, A.1    Koda, M.2    Sulkowska, M.3    Kanczuga-Koda, L.4    Wincewicz, D.5    Sulkowski, S.6
  • 137
    • 0142043003 scopus 로고    scopus 로고
    • Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival
    • Batra S, Perelman N, Luck LR, Shimada H, Malik P. Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival. Lab Invest. 2003; 83(10):1477-1487.
    • (2003) Lab Invest , vol.83 , Issue.10 , pp. 1477-1487
    • Batra, S.1    Perelman, N.2    Luck, L.R.3    Shimada, H.4    Malik, P.5
  • 138
    • 67651211931 scopus 로고    scopus 로고
    • Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia
    • Lam SY, Tipoe GL, Fung ML. Upregulation of erythropoietin and its receptor expression in the rat carotid body during chronic and intermittent hypoxia. Adv Exp Med Biol. 2009;648:207-214.
    • (2009) Adv Exp Med Biol , vol.648 , pp. 207-214
    • Lam, S.Y.1    Tipoe, G.L.2    Fung, M.L.3
  • 139
    • 78149304438 scopus 로고    scopus 로고
    • Up-regulation of erythropoietin receptor by nitric oxide mediates hypoxia preconditioning
    • Chen ZY, Wang L, Asavaritkrai P, Noguchi CT. Up-regulation of erythropoietin receptor by nitric oxide mediates hypoxia preconditioning. J Neurosci Res. 2010;88(14):3180-3188.
    • (2010) J Neurosci Res , vol.88 , Issue.14 , pp. 3180-3188
    • Chen, Z.Y.1    Wang, L.2    Asavaritkrai, P.3    Noguchi, C.T.4
  • 140
    • 0035328802 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor expression in human cancer
    • Acs G, Acs P, Beckwith SM, et al. Erythropoietin and erythropoietin receptor expression in human cancer. Cancer Res. 2001;61(9): 3561-3565.
    • (2001) Cancer Res , vol.61 , Issue.9 , pp. 3561-3565
    • Acs, G.1    Acs, P.2    Beckwith, S.M.3
  • 142
    • 0025977563 scopus 로고
    • Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
    • Pevny L, Simon MC, Robertson E, et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature. 1991;349(6306):257-260.
    • (1991) Nature , vol.349 , Issue.6306 , pp. 257-260
    • Pevny, L.1    Simon, M.C.2    Robertson, E.3
  • 143
    • 0026865123 scopus 로고
    • Rescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cells
    • Simon MC, Pevny L, Wiles MV, Keller G, Costantini F, Orkin SH. Rescue of erythroid development in gene targeted GATA-1- mouse embryonic stem cells. Nat Genet. 1992;1(2):92-98.
    • (1992) Nat Genet , vol.1 , Issue.2 , pp. 92-98
    • Simon, M.C.1    Pevny, L.2    Wiles, M.V.3    Keller, G.4    Costantini, F.5    Orkin, S.H.6
  • 144
    • 0031043574 scopus 로고    scopus 로고
    • Cell-cycle-dependent regulation of erythropoietin receptor gene
    • Komatsu N, Kirito K, Kashii Y, et al. Cell-cycle-dependent regulation of erythropoietin receptor gene. Blood. 1997;89(4):1182-1188.
    • (1997) Blood , vol.89 , Issue.4 , pp. 1182-1188
    • Komatsu, N.1    Kirito, K.2    Kashii, Y.3
  • 145
    • 0242411607 scopus 로고    scopus 로고
    • Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels
    • Suzuki N, Suwabe N, Ohneda O, et al. Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels. Blood. 2003;102(10):3575-3583.
    • (2003) Blood , vol.102 , Issue.10 , pp. 3575-3583
    • Suzuki, N.1    Suwabe, N.2    Ohneda, O.3
  • 146
    • 0025695387 scopus 로고
    • Progressive inactivation of the expression of an erythroid transcriptional factor in GM- and G-CSF-dependent myeloid cell lines
    • Crotta S, Nicolis S, Ronchi A, et al. Progressive inactivation of the expression of an erythroid transcriptional factor in GM- and G-CSF-dependent myeloid cell lines. Nucleic Acids Res. 1990;18(23):6863-6869.
    • (1990) Nucleic Acids Res , vol.18 , Issue.23 , pp. 6863-6869
    • Crotta, S.1    Nicolis, S.2    Ronchi, A.3
  • 147
    • 0026322997 scopus 로고
    • Response to erythropoietin in erythroid subclones of the factor-dependent cell line 32D is determined by translocation of the erythropoietin receptor to the cell surface
    • Migliaccio AR, Migliaccio G, D'Andrea A, et al. Response to erythropoietin in erythroid subclones of the factor-dependent cell line 32D is determined by translocation of the erythropoietin receptor to the cell surface. Proc Natl Acad Sci U S A 1991;88(24):11086-11090.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.24 , pp. 11086-11090
    • Migliaccio, A.R.1    Migliaccio, G.2    D'Andrea, A.3
  • 148
    • 0032522474 scopus 로고    scopus 로고
    • Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG
    • Tsang AP, Fujiwara Y, Hom DB, Orkin SH. Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG. Genes Dev. 1998;12(8):1176-1188.
    • (1998) Genes Dev , vol.12 , Issue.8 , pp. 1176-1188
    • Tsang, A.P.1    Fujiwara, Y.2    Hom, D.B.3    Orkin, S.H.4
  • 149
    • 70350371605 scopus 로고    scopus 로고
    • Translational isoforms of FOG1 regulate GATA1-interacting complexes
    • Snow JW, Orkin SH. Translational isoforms of FOG1 regulate GATA1-interacting complexes. J Biol Chem. 2009;284(43):29310-29319.
    • (2009) J Biol Chem , vol.284 , Issue.43 , pp. 29310-29319
    • Snow, J.W.1    Orkin, S.H.2
  • 150
    • 77955131763 scopus 로고    scopus 로고
    • Genome-wide identification of TAL1's functional targets: Insights into its mechanisms of action in primary erythroid cells
    • Kassouf MT, Hughes JR, Taylor S, et al. Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells. Genome Res. 2010;20(8):1064-1083.
    • (2010) Genome Res , vol.20 , Issue.8 , pp. 1064-1083
    • Kassouf, M.T.1    Hughes, J.R.2    Taylor, S.3
  • 151
    • 0037472895 scopus 로고    scopus 로고
    • Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene
    • Mikkola HK, Klintman J, Yang H, et al. Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature. 2003; 421(6922):547-551.
    • (2003) Nature , vol.421 , Issue.6922 , pp. 547-551
    • Mikkola, H.K.1    Klintman, J.2    Yang, H.3
  • 152
    • 0026090726 scopus 로고
    • Erythroid expression of the 'helix-loop-helix' gene, SCL
    • Green AR, Salvaris E, Begley CG. Erythroid expression of the 'helix-loop-helix' gene, SCL. Oncogene. 1991;6(3):475-479.
    • (1991) Oncogene , vol.6 , Issue.3 , pp. 475-479
    • Green, A.R.1    Salvaris, E.2    Begley, C.G.3
  • 153
    • 0026023097 scopus 로고
    • Differential expression of the LYL, SCL and E2 A helix-loop-helix genes within the hemopoietic system
    • Visvader J, Begley CG, Adams JM. Differential expression of the LYL, SCL and E2 A helix-loop-helix genes within the hemopoietic system. Oncogene. 1991;6(2):187-194.
    • (1991) Oncogene , vol.6 , Issue.2 , pp. 187-194
    • Visvader, J.1    Begley, C.G.2    Adams, J.M.3
  • 154
    • 58149348631 scopus 로고    scopus 로고
    • Role of the erythropoietin receptor in ETV6/RUNX1-positive acute lymphoblastic leukemia
    • Inthal A, Krapf G, Beck D, et al. Role of the erythropoietin receptor in ETV6/RUNX1-positive acute lymphoblastic leukemia. Clin Cancer Res. 2008;14(22):7196-7204.
    • (2008) Clin Cancer Res , vol.14 , Issue.22 , pp. 7196-7204
    • Inthal, A.1    Krapf, G.2    Beck, D.3
  • 155
    • 0026578516 scopus 로고
    • SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain
    • Green AR, Lints T, Visvader J, Harvey R, Begley CG. SCL is coexpressed with GATA-1 in hemopoietic cells but is also expressed in developing brain. Oncogene. 1992;7(4):653-660.
    • (1992) Oncogene , vol.7 , Issue.4 , pp. 653-660
    • Green, A.R.1    Lints, T.2    Visvader, J.3    Harvey, R.4    Begley, C.G.5
  • 156
    • 0028285242 scopus 로고
    • Different domains regulate the human erythropoietin receptor gene transcription
    • Maouche L, Cartron JP, Chretien S. Different domains regulate the human erythropoietin receptor gene transcription. Nucleic Acids Res. 1994;22(3):338-346.
    • (1994) Nucleic Acids Res , vol.22 , Issue.3 , pp. 338-346
    • Maouche, L.1    Cartron, J.P.2    Chretien, S.3
  • 158
    • 0030041323 scopus 로고    scopus 로고
    • Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: One high-affinity and one low-affinity interaction
    • Philo JS, Aoki KH, Arakawa T, Narhi LO, Wen J. Dimerization of the extracellular domain of the erythropoietin (EPO) receptor by EPO: one high-affinity and one low-affinity interaction. Biochemistry. 1996; 35(5):1681-1691.
    • (1996) Biochemistry , vol.35 , Issue.5 , pp. 1681-1691
    • Philo, J.S.1    Aoki, K.H.2    Arakawa, T.3    Narhi, L.O.4    Wen, J.5
  • 159
    • 0032188942 scopus 로고    scopus 로고
    • Efficiency of signalling through cytokine receptors depends critically on receptor orientation
    • Syed RS, Reid SW, Li C, et al. Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature. 1998;395(6701):511-516.
    • (1998) Nature , vol.395 , Issue.6701 , pp. 511-516
    • Syed, R.S.1    Reid, S.W.2    Li, C.3
  • 160
    • 0032856982 scopus 로고    scopus 로고
    • Activation of erythropoietin signaling by receptor dimerization
    • Watowich SS. Activation of erythropoietin signaling by receptor dimerization. Int J Biochem Cell Biol. 1999;31(10):1075-1088.
    • (1999) Int J Biochem Cell Biol , vol.31 , Issue.10 , pp. 1075-1088
    • Watowich, S.S.1
  • 161
    • 33644867127 scopus 로고    scopus 로고
    • Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP)
    • Gross AW, Lodish HF. Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP). J Biol Chem. 2006;281(4):2024-2032.
    • (2006) J Biol Chem , vol.281 , Issue.4 , pp. 2024-2032
    • Gross, A.W.1    Lodish, H.F.2
  • 162
    • 0032830149 scopus 로고    scopus 로고
    • Activation of the erythropoietin receptor is not required for internalization of bound erythropoietin
    • Beckman DL, Lin LL, Quinones ME, Longmore GD. Activation of the erythropoietin receptor is not required for internalization of bound erythropoietin. Blood. 1999;94(8):2667-2675.
    • (1999) Blood , vol.94 , Issue.8 , pp. 2667-2675
    • Beckman, D.L.1    Lin, L.L.2    Quinones, M.E.3    Longmore, G.D.4
  • 163
    • 0030966906 scopus 로고    scopus 로고
    • Changes in conformation and stability upon formation of complexes of erythropoietin (EPO) and soluble EPO receptor
    • Narhi LO, Aoki KH, Philo JS, Arakawa T. Changes in conformation and stability upon formation of complexes of erythropoietin (EPO) and soluble EPO receptor. J Protein Chem. 1997;16(3):213-225.
    • (1997) J Protein Chem , vol.16 , Issue.3 , pp. 213-225
    • Narhi, L.O.1    Aoki, K.H.2    Philo, J.S.3    Arakawa, T.4
  • 164
    • 0033548048 scopus 로고    scopus 로고
    • Erythropoietin receptor activation by a ligand-induced conformation change
    • Remy I, Wilson IA, Michnick SW. Erythropoietin receptor activation by a ligand-induced conformation change. Science. 1999; 283(5404):990-993.
    • (1999) Science , vol.283 , Issue.5404 , pp. 990-993
    • Remy, I.1    Wilson, I.A.2    Michnick, S.W.3
  • 165
    • 33646381647 scopus 로고    scopus 로고
    • Active conformation of the erythropoietin receptor: Random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains
    • Lu X, Gross AW, Lodish HF. Active conformation of the erythropoietin receptor: random and cysteine-scanning mutagenesis of the extracellular juxtamembrane and transmembrane domains. J Biol Chem. 2006;281(11):7002-7011.
    • (2006) J Biol Chem , vol.281 , Issue.11 , pp. 7002-7011
    • Lu, X.1    Gross, A.W.2    Lodish, H.F.3
  • 167
    • 0036408435 scopus 로고    scopus 로고
    • Differential roles of SOCS family members in EpoR signal transduction
    • Jegalian AG, Wu H. Differential roles of SOCS family members in EpoR signal transduction. J Interferon Cytokine Res. 2002; 22(8):853-860.
    • (2002) J Interferon Cytokine Res , vol.22 , Issue.8 , pp. 853-860
    • Jegalian, A.G.1    Wu, H.2
  • 168
    • 0842328827 scopus 로고    scopus 로고
    • A novel SHP-1/Grb2-dependent mechanism of negative regulation of cytokine-receptor signaling: Contribution of SHP-1 C-terminal tyrosines in cytokine signaling
    • Minoo P, Zadeh MM, Rottapel R, Lebrun JJ, Ali S. A novel SHP-1/Grb2-dependent mechanism of negative regulation of cytokine-receptor signaling: contribution of SHP-1 C-terminal tyrosines in cytokine signaling. Blood. 2004;103(4):1398-1407.
    • (2004) Blood , vol.103 , Issue.4 , pp. 1398-1407
    • Minoo, P.1    Zadeh, M.M.2    Rottapel, R.3    Lebrun, J.J.4    Ali, S.5
  • 169
    • 0034674778 scopus 로고    scopus 로고
    • Proteasomes regulate the duration of erythropoietin receptor activation by controlling down-regulation of cell surface receptors
    • Verdier F, Walrafen P, Hubert N, et al. Proteasomes regulate the duration of erythropoietin receptor activation by controlling down-regulation of cell surface receptors. J Biol Chem. 2000;275(24):18375-18381.
    • (2000) J Biol Chem , vol.275 , Issue.24 , pp. 18375-18381
    • Verdier, F.1    Walrafen, P.2    Hubert, N.3
  • 170
    • 0035936596 scopus 로고    scopus 로고
    • Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor
    • Kubatzky KF, Ruan W, Gurezka R, et al. Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor. Curr Biol. 2001;11(2):110-115.
    • (2001) Curr Biol , vol.11 , Issue.2 , pp. 110-115
    • Kubatzky, K.F.1    Ruan, W.2    Gurezka, R.3
  • 171
    • 40749112317 scopus 로고    scopus 로고
    • Optimization and utilization of the SureFire phospho-STAT5 assay for a cell-based screening campaign
    • Binder C, Lafayette A, Archibeque I, et al. Optimization and utilization of the SureFire phospho-STAT5 assay for a cell-based screening campaign. Assay Drug Dev Technol. 2008;6(1):27-37.
    • (2008) Assay Drug Dev Technol , vol.6 , Issue.1 , pp. 27-37
    • Binder, C.1    Lafayette, A.2    Archibeque, I.3
  • 172
    • 0028894109 scopus 로고
    • Characterization of three erythropoietin (Epo)-binding proteins in various human Epo-responsive cell lines and in cells transfected with human Epo-receptor cDNA
    • Takahashi T, Chiba S, Hirano N, Yazaki Y, Hirai H. Characterization of three erythropoietin (Epo)-binding proteins in various human Epo-responsive cell lines and in cells transfected with human Epo-receptor cDNA. Blood. 1995;85(1):106-114.
    • (1995) Blood , vol.85 , Issue.1 , pp. 106-114
    • Takahashi, T.1    Chiba, S.2    Hirano, N.3    Yazaki, Y.4    Hirai, H.5
  • 173
    • 0027969025 scopus 로고
    • Erythropoietin increases the radioresistance of a clonal hematopoietic progenitor cell line expressing a transgene for the erythropoietin receptor
    • Santucci MA, Pierce JH, Zannini S, et al. Erythropoietin increases the radioresistance of a clonal hematopoietic progenitor cell line expressing a transgene for the erythropoietin receptor. Stem Cells. 1994;12(5):506-513.
    • (1994) Stem Cells , vol.12 , Issue.5 , pp. 506-513
    • Santucci, M.A.1    Pierce, J.H.2    Zannini, S.3
  • 174
    • 0027467218 scopus 로고
    • Structure-function analysis of human IL-6 receptor: Dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130
    • Yawata H, Yasukawa K, Natsuka S, et al. Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130. EMBO J. 1993;12(4):1705-1712.
    • (1993) EMBO J , vol.12 , Issue.4 , pp. 1705-1712
    • Yawata, H.1    Yasukawa, K.2    Natsuka, S.3
  • 175
    • 0036530041 scopus 로고    scopus 로고
    • Erythropoietin receptor haploinsufficiency and in vivo interplay with granulocyte-macrophage colony-stimulating factor and interleukin 3
    • Jegalian AG, Acurio A, Dranoff G, Wu H. Erythropoietin receptor haploinsufficiency and in vivo interplay with granulocyte-macrophage colony-stimulating factor and interleukin 3. Blood. 2002;99(7):2603-2605.
    • (2002) Blood , vol.99 , Issue.7 , pp. 2603-2605
    • Jegalian, A.G.1    Acurio, A.2    Dranoff, G.3    Wu, H.4
  • 176
    • 33846239262 scopus 로고    scopus 로고
    • A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells
    • Um M, Gross AW, Lodish HF. A "classical" homodimeric erythropoietin receptor is essential for the antiapoptotic effects of erythropoietin on differentiated neuroblastoma SH-SY5Y and pheochromocytoma PC-12 cells. Cell Signal. 2007;19(3):634-645.
    • (2007) Cell Signal , vol.19 , Issue.3 , pp. 634-645
    • Um, M.1    Gross, A.W.2    Lodish, H.F.3
  • 177
    • 33644974691 scopus 로고    scopus 로고
    • Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells
    • Pregi N, Vittori D, Perez G, Leiros CP, Nesse A. Effect of erythropoietin on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. Biochim Biophys Acta. 2006; 1763(2):238-246.
    • (2006) Biochim Biophys Acta , vol.1763 , Issue.2 , pp. 238-246
    • Pregi, N.1    Vittori, D.2    Perez, G.3    Leiros, C.P.4    Nesse, A.5
  • 178
    • 16644380412 scopus 로고    scopus 로고
    • Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site
    • Rossler J, Stolze I, Frede S, et al. Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site. J Cell Biochem. 2004;93(1):153-161.
    • (2004) J Cell Biochem , vol.93 , Issue.1 , pp. 153-161
    • Rossler, J.1    Stolze, I.2    Frede, S.3
  • 179
    • 4744350723 scopus 로고    scopus 로고
    • Malignant hematopoietic cell lines: In vitro models for the study of erythroleukemia
    • Drexler HG, Matsuo Y, MacLeod RA. Malignant hematopoietic cell lines: in vitro models for the study of erythroleukemia. Leuk Res. 2004;28(12):1243-1251.
    • (2004) Leuk Res , vol.28 , Issue.12 , pp. 1243-1251
    • Drexler, H.G.1    Matsuo, Y.2    Macleod, R.A.3
  • 180
    • 0023676980 scopus 로고
    • Characterization of erythropoietin receptor on erythropoietin-unresponsive mouse erythroleukemia cells
    • Todokoro K, Kanazawa S, Amanuma H, Ikawa Y. Characterization of erythropoietin receptor on erythropoietin-unresponsive mouse erythroleukemia cells. Biochim Biophys Acta. 1988;943(2): 326-330.
    • (1988) Biochim Biophys Acta , vol.943 , Issue.2 , pp. 326-330
    • Todokoro, K.1    Kanazawa, S.2    Amanuma, H.3    Ikawa, Y.4
  • 181
    • 0023133951 scopus 로고
    • Murine erythroleukaemia cells (Friend cells) possess high-affinity binding sites for erythropoietin
    • Mayeux P, Billat C, Jacquot R. Murine erythroleukaemia cells (Friend cells) possess high-affinity binding sites for erythropoietin. FEBS Lett. 1987;211(2):229-233.
    • (1987) FEBS Lett , vol.211 , Issue.2 , pp. 229-233
    • Mayeux, P.1    Billat, C.2    Jacquot, R.3
  • 182
    • 0025738139 scopus 로고
    • The erythropoietin receptor gene: Cloning and identification of multiple transcripts in an erythroid cell line OCIM1
    • Ehrenman K, St JT. The erythropoietin receptor gene: cloning and identification of multiple transcripts in an erythroid cell line OCIM1. Exp Hematol. 1991;19(9):973-977.
    • (1991) Exp Hematol , vol.19 , Issue.9 , pp. 973-977
    • Ehrenman, K.1    St, J.T.2
  • 183
    • 0033603435 scopus 로고    scopus 로고
    • Signaling pathways activated by oncogenic forms of Abl tyrosine kinase
    • Zou X, Calame K. Signaling pathways activated by oncogenic forms of Abl tyrosine kinase. J Biol Chem. 1999;274(26):18141-18144.
    • (1999) J Biol Chem , vol.274 , Issue.26 , pp. 18141-18144
    • Zou, X.1    Calame, K.2
  • 184
    • 0016640079 scopus 로고
    • Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome
    • Lozzio CB, Lozzio BB. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. Blood. 1975;45(3): 321-334.
    • (1975) Blood , vol.45 , Issue.3 , pp. 321-334
    • Lozzio, C.B.1    Lozzio, B.B.2
  • 185
    • 84864406372 scopus 로고    scopus 로고
    • Lack of expression and function of erythropoietin receptors in kidney. Nephrol Dial Transplant. 2012
    • Elliott S, Busse L, Swift S, et al. Lack of expression and function of erythropoietin receptors in kidney. Nephrol Dial Transplant. 2012. Epub December 13, 2011.
    • (2011) Epub December , pp. 13
    • Elliott, S.1    Busse, L.2    Swift, S.3
  • 186
    • 0033168645 scopus 로고    scopus 로고
    • Genetic evidence for an additional factor required for erythropoietin-induced signal transduction
    • Gaffen SL, Lai SY, Longmore GD, Liu KD, Goldsmith MA. Genetic evidence for an additional factor required for erythropoietin-induced signal transduction. Blood. 1999;94(1):74-86.
    • (1999) Blood , vol.94 , Issue.1 , pp. 74-86
    • Gaffen, S.L.1    Lai, S.Y.2    Longmore, G.D.3    Liu, K.D.4    Goldsmith, M.A.5
  • 187
    • 0025891691 scopus 로고
    • Activation of the erythropoietin receptor in stable lymphoid and myeloid transfectants
    • D'Andrea AD, Jones SS. Activation of the erythropoietin receptor in stable lymphoid and myeloid transfectants. Semin Hematol. 1991; 28(2):152-157.
    • (1991) Semin Hematol , vol.28 , Issue.2 , pp. 152-157
    • D'Andrea, A.D.1    Jones, S.S.2
  • 188
    • 0029899183 scopus 로고    scopus 로고
    • A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines
    • Shikama Y, Barber DL, D'Andrea AD, Sieff CA. A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines. Blood. 1996;88(2):455-464.
    • (1996) Blood , vol.88 , Issue.2 , pp. 455-464
    • Shikama, Y.1    Barber, D.L.2    D'Andrea, A.D.3    Sieff, C.A.4
  • 189
    • 0029060110 scopus 로고
    • Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways
    • Wakao H, Harada N, Kitamura T, Mui AL, Miyajima A. Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways. EMBO J. 1995;14(11):2527-2535.
    • (1995) EMBO J , vol.14 , Issue.11 , pp. 2527-2535
    • Wakao, H.1    Harada, N.2    Kitamura, T.3    Mui, A.L.4    Miyajima, A.5
  • 190
    • 0027079357 scopus 로고
    • Distinct downstream signaling mechanism between erythropoietin receptor and interleukin-2 receptor
    • Yamamura Y, Kageyama Y, Matuzaki T, Noda M, Ikawa Y. Distinct downstream signaling mechanism between erythropoietin receptor and interleukin-2 receptor. EMBO J. 1992;11(13):4909-4915.
    • (1992) EMBO J , vol.11 , Issue.13 , pp. 4909-4915
    • Yamamura, Y.1    Kageyama, Y.2    Matuzaki, T.3    Noda, M.4    Ikawa, Y.5
  • 191
    • 0029134822 scopus 로고
    • Acquired erythropoietin responsiveness of interleukin-2-dependent T lymphocytes retrovirally transduced with genes encoding chimeric erythropoietin/interleukin-2 receptors
    • Minamoto S, Treisman J, Hankins WD, Sugamura K, Rosenberg SA. Acquired erythropoietin responsiveness of interleukin-2-dependent T lymphocytes retrovirally transduced with genes encoding chimeric erythropoietin/interleukin-2 receptors. Blood. 1995;86(6):2281-2287.
    • (1995) Blood , vol.86 , Issue.6 , pp. 2281-2287
    • Minamoto, S.1    Treisman, J.2    Hankins, W.D.3    Sugamura, K.4    Rosenberg, S.A.5
  • 192
    • 0026326555 scopus 로고
    • An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
    • Longmore GD, Lodish HF. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: a cytokine receptor superfamily oncogene. Cell. 1991;67(6):1089-1102.
    • (1991) Cell , vol.67 , Issue.6 , pp. 1089-1102
    • Longmore, G.D.1    Lodish, H.F.2
  • 193
    • 80052527859 scopus 로고    scopus 로고
    • Downregulation of erythropoietin receptor by overexpression of phospholipase C-gamma 1 is critical for decrease on focal adhesion in transformed cells
    • Kang JK, Chang CH, Nam HJ, et al. Downregulation of erythropoietin receptor by overexpression of phospholipase C-gamma 1 is critical for decrease on focal adhesion in transformed cells. Cell Oncol. 2011;34(1):11-21.
    • (2011) Cell Oncol , vol.34 , Issue.1 , pp. 11-21
    • Kang, J.K.1    Chang, C.H.2    Nam, H.J.3
  • 194
    • 33846619565 scopus 로고    scopus 로고
    • Expression of GATA-1 in a non-hematopoietic cell line induces beta-globin locus control region chromatin structure remodeling and an erythroid pattern of gene expression
    • Layon ME, Ackley CJ, West RJ, Lowrey CH. Expression of GATA-1 in a non-hematopoietic cell line induces beta-globin locus control region chromatin structure remodeling and an erythroid pattern of gene expression. J Mol Biol. 2007;366(3):737-744.
    • (2007) J Mol Biol , vol.366 , Issue.3 , pp. 737-744
    • Layon, M.E.1    Ackley, C.J.2    West, R.J.3    Lowrey, C.H.4
  • 195
    • 0028073675 scopus 로고
    • Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor
    • Miura Y, Miura O, Ihle JN, Aoki N. Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor. J Biol Chem. 1994;269(47):29962-29969.
    • (1994) J Biol Chem , vol.269 , Issue.47 , pp. 29962-29969
    • Miura, Y.1    Miura, O.2    Ihle, J.N.3    Aoki, N.4
  • 196
    • 0022800183 scopus 로고
    • Growth factor requirements of oncogene-transformed NIH 3T3 and BALB/c 3T3 cells cultured in defined media
    • Zhan X, Goldfarb M. Growth factor requirements of oncogene-transformed NIH 3T3 and BALB/c 3T3 cells cultured in defined media. Mol Cell Biol. 1986;6(10):3541-3544.
    • (1986) Mol Cell Biol , vol.6 , Issue.10 , pp. 3541-3544
    • Zhan, X.1    Goldfarb, M.2
  • 197
    • 0027969055 scopus 로고
    • Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation
    • Pharr PN, Ogawa M, Hofbauer A, Longmore GD. Expression of an activated erythropoietin or a colony-stimulating factor 1 receptor by pluripotent progenitors enhances colony formation but does not induce differentiation. Proc Natl Acad Sci U S A. 1994;91(16):7482-7486.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.16 , pp. 7482-7486
    • Pharr, P.N.1    Ogawa, M.2    Hofbauer, A.3    Longmore, G.D.4
  • 198
    • 0027367954 scopus 로고
    • Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor
    • Longmore GD, Pharr P, Neumann D, Lodish HF. Both megakaryocytopoiesis and erythropoiesis are induced in mice infected with a retrovirus expressing an oncogenic erythropoietin receptor. Blood. 1993;82(8):2386-2395.
    • (1993) Blood , vol.82 , Issue.8 , pp. 2386-2395
    • Longmore, G.D.1    Pharr, P.2    Neumann, D.3    Lodish, H.F.4
  • 199
    • 0028278740 scopus 로고
    • A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells
    • Longmore GD, Pharr PN, Lodish HF. A constitutively activated erythropoietin receptor stimulates proliferation and contributes to transformation of multipotent, committed nonerythroid and erythroid progenitor cells. Mol Cell Biol. 1994;14(4):2266-2277.
    • (1994) Mol Cell Biol , vol.14 , Issue.4 , pp. 2266-2277
    • Longmore, G.D.1    Pharr, P.N.2    Lodish, H.F.3
  • 200
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial
    • Henke M, Laszig R, Rube C, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet. 2003; 362(9392):1255-1260.
    • (2003) Lancet , vol.362 , Issue.9392 , pp. 1255-1260
    • Henke, M.1    Laszig, R.2    Rube, C.3
  • 201
    • 33750588816 scopus 로고    scopus 로고
    • Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
    • Henke M, Mattern D, Pepe M, et al. Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol. 2006;24(29):4708-4713.
    • (2006) J Clin Oncol , vol.24 , Issue.29 , pp. 4708-4713
    • Henke, M.1    Mattern, D.2    Pepe, M.3
  • 202
    • 79955643654 scopus 로고    scopus 로고
    • Erythropoietin for oncology supportive care
    • (9 Special Issue SI)
    • McKinney M, Arcasoy MO. Erythropoietin for oncology supportive care. Exp Cell Res. 2011;317(9 Special Issue SI):1246-1254.
    • (2011) Exp Cell Res , vol.317 , pp. 1246-1254
    • McKinney, M.1    Arcasoy, M.O.2
  • 203
    • 77953691205 scopus 로고    scopus 로고
    • The role of erythropoietin and its receptor in growth, survival and therapeutic response of human tumor cells. From clinic to bench - a critical review
    • Szenajch J, Wcislo G, Jeong JY, Szczylik C, Feldman L. The role of erythropoietin and its receptor in growth, survival and therapeutic response of human tumor cells. From clinic to bench - a critical review. Biochim Biophys Acta. 2010;1806(1):82-95.
    • (2010) Biochim Biophys Acta , vol.1806 , Issue.1 , pp. 82-95
    • Szenajch, J.1    Wcislo, G.2    Jeong, J.Y.3    Szczylik, C.4    Feldman, L.5
  • 205
    • 40549113957 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents: Favorable safety profile when used as indicated
    • Nowrousian MR, Dunst J, Vaupel P. Erythropoiesis-stimulating agents: favorable safety profile when used as indicated. Strahlenther Onkol. 2008;184(3):121-136.
    • (2008) Strahlenther Onkol , vol.184 , Issue.3 , pp. 121-136
    • Nowrousian, M.R.1    Dunst, J.2    Vaupel, P.3
  • 206
    • 70249134095 scopus 로고    scopus 로고
    • Erythroid-stimulating agents in cancer therapy: Potential dangers and biologic mechanisms
    • Hadland BK, Longmore GD. Erythroid-stimulating agents in cancer therapy: potential dangers and biologic mechanisms. J Clin Oncol. 2009; (25):4217-4226.
    • (2009) J Clin Oncol , Issue.25 , pp. 4217-4226
    • Hadland, B.K.1    Longmore, G.D.2
  • 207
    • 0028891253 scopus 로고
    • A translocated erythropoietin receptor gene in a human erythroleukemia cell line (TF-1) expresses an abnormal transcript and a truncated protein
    • Winkelmann JC, Ward J, Mayeux P, Lacombe C, Schimmenti L, Jenkins RB. A translocated erythropoietin receptor gene in a human erythroleukemia cell line (TF-1) expresses an abnormal transcript and a truncated protein. Blood. 1995;85(1):179-185.
    • (1995) Blood , vol.85 , Issue.1 , pp. 179-185
    • Winkelmann, J.C.1    Ward, J.2    Mayeux, P.3    Lacombe, C.4    Schimmenti, L.5    Jenkins, R.B.6
  • 208
    • 0028270131 scopus 로고
    • Putative oncogenic role of the erythropoietin receptor in murine and human erythroleukemia cells
    • Chretien S, Moreau-Gachelin F, Apiou F, et al. Putative oncogenic role of the erythropoietin receptor in murine and human erythroleukemia cells. Blood. 1994;83(7):1813-1821.
    • (1994) Blood , vol.83 , Issue.7 , pp. 1813-1821
    • Chretien, S.1    Moreau-Gachelin, F.2    Apiou, F.3
  • 209
    • 0031026904 scopus 로고    scopus 로고
    • Activating mutations in cytokine receptors: Implications for receptor function and role in disease
    • Gonda TJ, D'Andrea RJ. Activating mutations in cytokine receptors: implications for receptor function and role in disease. Blood. 1997;89(2):355-369.
    • (1997) Blood , vol.89 , Issue.2 , pp. 355-369
    • Gonda, T.J.1    D'Andrea, R.J.2
  • 210
    • 0030021792 scopus 로고    scopus 로고
    • Missense mutation of the erythropoietin receptor is a rare event in human erythroid malignancies
    • Le Couedic JP, Mitjavila MT, Villeval JL, et al. Missense mutation of the erythropoietin receptor is a rare event in human erythroid malignancies. Blood. 1996;87(4):1502-1511.
    • (1996) Blood , vol.87 , Issue.4 , pp. 1502-1511
    • Le Couedic, J.P.1    Mitjavila, M.T.2    Villeval, J.L.3
  • 211
    • 0026658699 scopus 로고
    • Molecular mimicry of erythropoietin by the spleen focus-forming virus gp55 glycoprotein: The first stage of Friend virus-induced erythroleukemia
    • D'Andrea AD, Moreau JF, Showers MO. Molecular mimicry of erythropoietin by the spleen focus-forming virus gp55 glycoprotein: the first stage of Friend virus-induced erythroleukemia. Biochim Biophys Acta. 1992;1114(1):31-41.
    • (1992) Biochim Biophys Acta , vol.1114 , Issue.1 , pp. 31-41
    • D'Andrea, A.D.1    Moreau, J.F.2    Showers, M.O.3
  • 212
    • 56849087289 scopus 로고    scopus 로고
    • Multi-stage Friend murine erythroleukemia: Molecular insights into oncogenic cooperation
    • Moreau-Gachelin F. Multi-stage Friend murine erythroleukemia: molecular insights into oncogenic cooperation. Retrovirology. 2008;5:99.
    • (2008) Retrovirology , vol.5 , pp. 99
    • Moreau-Gachelin, F.1
  • 213
    • 0025633003 scopus 로고
    • Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity
    • Yoshimura A, Longmore G, Lodish HF. Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity. Nature. 1990; 348(6302):647-649.
    • (1990) Nature , vol.348 , Issue.6302 , pp. 647-649
    • Yoshimura, A.1    Longmore, G.2    Lodish, H.F.3
  • 214
    • 34447332571 scopus 로고    scopus 로고
    • Molecular genetic analyses in familial and sporadic congenital primary erythrocytosis
    • Rives S, Pahl HL, Florensa L, et al. Molecular genetic analyses in familial and sporadic congenital primary erythrocytosis. Haematologica. 2007;92(5):674-677.
    • (2007) Haematologica , vol.92 , Issue.5 , pp. 674-677
    • Rives, S.1    Pahl, H.L.2    Florensa, L.3
  • 215
    • 46849114121 scopus 로고    scopus 로고
    • A study of 36 unrelated cases with pure erythrocytosis revealed three new mutations in the erythropoietin receptor gene
    • Al-Sheikh M, Mazurier E, Gardie B, et al. A study of 36 unrelated cases with pure erythrocytosis revealed three new mutations in the erythropoietin receptor gene. Haematologica. 2008;93(7):1072-1075.
    • (2008) Haematologica , vol.93 , Issue.7 , pp. 1072-1075
    • Al-Sheikh, M.1    Mazurier, E.2    Gardie, B.3
  • 216
    • 0033215521 scopus 로고    scopus 로고
    • Erythropoietin receptor mutations associated with familial erythrocytosis cause hypersensitivity to erythropoietin in the heterozygous state
    • Watowich SS, Xie X, Klingmuller U, et al. Erythropoietin receptor mutations associated with familial erythrocytosis cause hypersensitivity to erythropoietin in the heterozygous state. Blood. 1999;94(7):2530-2532.
    • (1999) Blood , vol.94 , Issue.7 , pp. 2530-2532
    • Watowich, S.S.1    Xie, X.2    Klingmuller, U.3
  • 217
    • 0027215519 scopus 로고
    • Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis
    • de la Chapelle A, Traskelin AL, Juvonen E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci U S A. 1993;90(10):4495-4499.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.10 , pp. 4495-4499
    • de la Chapelle, A.1    Traskelin, A.L.2    Juvonen, E.3
  • 218
    • 2342631195 scopus 로고    scopus 로고
    • Congenital disorder of oxygen sensing: Association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors
    • Gordeuk VR, Sergueeva AI, Miasnikova GY, et al. Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood. 2004;103(10):3924-3932.
    • (2004) Blood , vol.103 , Issue.10 , pp. 3924-3932
    • Gordeuk, V.R.1    Sergueeva, A.I.2    Miasnikova, G.Y.3
  • 219
    • 0038751965 scopus 로고    scopus 로고
    • Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression
    • Acs G, Zhang PJ, McGrath CM, et al. Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. Am J Pathol. 2003;162(6):1789-1806.
    • (2003) Am J Pathol , vol.162 , Issue.6 , pp. 1789-1806
    • Acs, G.1    Zhang, P.J.2    McGrath, C.M.3
  • 220
    • 0037767746 scopus 로고    scopus 로고
    • Expression of erythropoietin receptor splice variants in human cancer
    • Arcasoy MO, Jiang X, Haroon ZA. Expression of erythropoietin receptor splice variants in human cancer. Biochem Biophys Res Commun. 2003;307(4):999-1007.
    • (2003) Biochem Biophys Res Commun , vol.307 , Issue.4 , pp. 999-1007
    • Arcasoy, M.O.1    Jiang, X.2    Haroon, Z.A.3
  • 221
    • 0142043003 scopus 로고    scopus 로고
    • Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival
    • Batra S, Perelman N, Luck LR, Shimada H, Malik P. Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival. Lab Invest. 2003;83(10):1477-1487.
    • (2003) Lab Invest , vol.83 , Issue.10 , pp. 1477-1487
    • Batra, S.1    Perelman, N.2    Luck, L.R.3    Shimada, H.4    Malik, P.5
  • 222
    • 31944444232 scopus 로고    scopus 로고
    • Erythropoietin stimulates growth and STAT5 phosphorylation in human prostate epithelial and prostate cancer cells
    • Feldman L, Wang Y, Rhim JS, Bhattacharya N, Loda M, Sytkowski AJ. Erythropoietin stimulates growth and STAT5 phosphorylation in human prostate epithelial and prostate cancer cells. Prostate. 2006;66(2):135-145.
    • (2006) Prostate , vol.66 , Issue.2 , pp. 135-145
    • Feldman, L.1    Wang, Y.2    Rhim, J.S.3    Bhattacharya, N.4    Loda, M.5    Sytkowski, A.J.6
  • 223
    • 76149088759 scopus 로고    scopus 로고
    • Effect of erythropoietin on human tumor growth in xenograft models
    • Kataoka M, Moriya Y, Moriguchi Y, et al. Effect of erythropoietin on human tumor growth in xenograft models. Mol Med Report. 2010;3(1):95-101.
    • (2010) Mol Med Report , vol.3 , Issue.1 , pp. 95-101
    • Kataoka, M.1    Moriya, Y.2    Moriguchi, Y.3
  • 224
    • 21744451644 scopus 로고    scopus 로고
    • Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma
    • Lai SY, Childs EE, Xi S, et al. Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene. 2005;24(27): 4442-4449.
    • (2005) Oncogene , vol.24 , Issue.27 , pp. 4442-4449
    • Lai, S.Y.1    Childs, E.E.2    Xi, S.3
  • 225
    • 69949089786 scopus 로고    scopus 로고
    • Erythropoietin receptor expression and correlation to tamoxifen response and prognosis in breast cancer
    • Larsson AM, Jirstrom K, Fredlund E, et al. Erythropoietin receptor expression and correlation to tamoxifen response and prognosis in breast cancer. Clin Cancer Res. 2009;15(17):5552-5559.
    • (2009) Clin Cancer Res , vol.15 , Issue.17 , pp. 5552-5559
    • Larsson, A.M.1    Jirstrom, K.2    Fredlund, E.3
  • 226
    • 0036269105 scopus 로고    scopus 로고
    • Erythropoietin and G-CSF receptors in human tumor cells: Expression and aspects regarding functionality
    • Westphal G, Niederberger E, Blum C, et al. Erythropoietin and G-CSF receptors in human tumor cells: expression and aspects regarding functionality. Tumori. 2002;88(2):150-159.
    • (2002) Tumori , vol.88 , Issue.2 , pp. 150-159
    • Westphal, G.1    Niederberger, E.2    Blum, C.3
  • 227
    • 0037479926 scopus 로고    scopus 로고
    • Erythropoietin regulates tumour growth of human malignancies
    • Yasuda Y, Fujita Y, Matsuo T, et al. Erythropoietin regulates tumour growth of human malignancies. Carcinogenesis. 2003;24(6): 1021-1029.
    • (2003) Carcinogenesis , vol.24 , Issue.6 , pp. 1021-1029
    • Yasuda, Y.1    Fujita, Y.2    Matsuo, T.3
  • 228
    • 0036850611 scopus 로고    scopus 로고
    • Erythropoietin is involved in growth and angiogenesis in malignant tumours of female reproductive organs
    • Yasuda Y, Fujita Y, Masuda S, et al. Erythropoietin is involved in growth and angiogenesis in malignant tumours of female reproductive organs. Carcinogenesis. 2002;23(11):1797-1805.
    • (2002) Carcinogenesis , vol.23 , Issue.11 , pp. 1797-1805
    • Yasuda, Y.1    Fujita, Y.2    Masuda, S.3
  • 229
    • 77951177512 scopus 로고    scopus 로고
    • Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line
    • Shi Z, Hodges VM, Dunlop EA, et al. Erythropoietin-induced activation of the JAK2/STAT5, PI3K/Akt, and Ras/ERK pathways promotes malignant cell behavior in a modified breast cancer cell line. Mol Cancer Res. 2010;8(4):615-626.
    • (2010) Mol Cancer Res , vol.8 , Issue.4 , pp. 615-626
    • Shi, Z.1    Hodges, V.M.2    Dunlop, E.A.3
  • 230
    • 70349313947 scopus 로고    scopus 로고
    • Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial
    • Miller CP, lowe KA, Valliant-Saunders K, et al. Evaluating erythropoietin-associated tumor progression using archival tissues from a phase III clinical trial. Stem Cells. 2009;27(9):2353-2361.
    • (2009) Stem Cells , vol.27 , Issue.9 , pp. 2353-2361
    • Miller, C.P.1    Lowe, K.A.2    Valliant-Saunders, K.3
  • 231
    • 11244267556 scopus 로고    scopus 로고
    • Darbepoietin alfa potentiates the efficacy of radiation therapy in mice with corrected or uncorrected anemia
    • Ning S, Hartley C, Molineux G, Knox SJ. Darbepoietin alfa potentiates the efficacy of radiation therapy in mice with corrected or uncorrected anemia. Cancer Res. 2005;65(1):284-290.
    • (2005) Cancer Res , vol.65 , Issue.1 , pp. 284-290
    • Ning, S.1    Hartley, C.2    Molineux, G.3    Knox, S.J.4
  • 232
    • 65349147053 scopus 로고    scopus 로고
    • RNA interference-mediated inhibition of erythropoietin receptor expression suppresses tumor growth and invasiveness in A2780 human ovarian carcinoma cells
    • Paragh G, Kumar SM, Rakosy Z, Choi SC, Xu X, Acs G. RNA interference-mediated inhibition of erythropoietin receptor expression suppresses tumor growth and invasiveness in A2780 human ovarian carcinoma cells. Am J Pathol. 2009;174(4):1504-1514.
    • (2009) Am J Pathol , vol.174 , Issue.4 , pp. 1504-1514
    • Paragh, G.1    Kumar, S.M.2    Rakosy, Z.3    Choi, S.C.4    Xu, X.5    Acs, G.6
  • 233
    • 70350060348 scopus 로고    scopus 로고
    • No direct effects of erythropoietin beta on a head and neck squamous cell carcinoma cell line which is growth stimulated in vivo
    • Sasaki Y, Kjellen E, Mineta H, Wennerberg J, Ekblad L. No direct effects of erythropoietin beta on a head and neck squamous cell carcinoma cell line which is growth stimulated in vivo. Acta Oncol. 2009;48(7):1062-1069.
    • (2009) Acta Oncol , vol.48 , Issue.7 , pp. 1062-1069
    • Sasaki, Y.1    Kjellen, E.2    Mineta, H.3    Wennerberg, J.4    Ekblad, L.5
  • 234
    • 0028261161 scopus 로고
    • The expression and role of human erythropoietin receptor in erythroid and nonerythroid cells
    • Williams DM, Zimmers TA, Pierce JH, et al. The expression and role of human erythropoietin receptor in erythroid and nonerythroid cells. Ann N Y Acad Sci. 1994;718:232-243.
    • (1994) Ann N Y Acad Sci , vol.718 , pp. 232-243
    • Williams, D.M.1    Zimmers, T.A.2    Pierce, J.H.3
  • 235
    • 0027302375 scopus 로고
    • Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells
    • Masuda S, Nagao M, Takahata K, et al. Functional erythropoietin receptor of the cells with neural characteristics. Comparison with receptor properties of erythroid cells. J Biol Chem. 1993;268(15): 11208-11216.
    • (1993) J Biol Chem , vol.268 , Issue.15 , pp. 11208-11216
    • Masuda, S.1    Nagao, M.2    Takahata, K.3
  • 236
    • 34548094540 scopus 로고    scopus 로고
    • Erythropoietin and erythropoietin receptor coexpression is associated with poor survival in stage I non-small cell lung cancer
    • Saintigny P, Besse B, Callard P, et al. Erythropoietin and erythropoietin receptor coexpression is associated with poor survival in stage I non-small cell lung cancer. Clin Cancer Res. 2007;13(16): 4825-4831.
    • (2007) Clin Cancer Res , vol.13 , Issue.16 , pp. 4825-4831
    • Saintigny, P.1    Besse, B.2    Callard, P.3
  • 237
    • 41649096606 scopus 로고    scopus 로고
    • Human recombinant erythropoietin does not promote cancer growth in presence of functional receptors expressed in cancer cells
    • Belda-Iniesta C, Perona R, Carpeno JC, et al. Human recombinant erythropoietin does not promote cancer growth in presence of functional receptors expressed in cancer cells. Cancer Biol Ther. 2007; 6(10):1600-1605.
    • (2007) Cancer Biol Ther , vol.6 , Issue.10 , pp. 1600-1605
    • Belda-Iniesta, C.1    Perona, R.2    Carpeno, J.C.3
  • 238
    • 28044441545 scopus 로고    scopus 로고
    • Erythropoietin receptor function and expression in epithelial ovarian carcinoma
    • McBroom JW, Acs G, Rose GS, Krivak TC, Mohyeldin A, Verma A. Erythropoietin receptor function and expression in epithelial ovarian carcinoma. Gynecol Oncol. 2005;99(3):571-577.
    • (2005) Gynecol Oncol , vol.99 , Issue.3 , pp. 571-577
    • McBroom, J.W.1    Acs, G.2    Rose, G.S.3    Krivak, T.C.4    Mohyeldin, A.5    Verma, A.6
  • 239
    • 79955594639 scopus 로고    scopus 로고
    • Prognostic Impact of erythropoietin expression and erythropoietin receptor expression on locoregional control and survival of patients irradiated for stage ii/iii non-small-cell lung cancer
    • Rades D, Setter C, Dahl O, Schild SE, Noack F. Prognostic Impact of erythropoietin expression and erythropoietin receptor expression on locoregional control and survival of patients irradiated for stage ii/iii non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2011; 80(2):499-505.
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , Issue.2 , pp. 499-505
    • Rades, D.1    Setter, C.2    Dahl, O.3    Schild, S.E.4    Noack, F.5
  • 240
    • 41749118318 scopus 로고    scopus 로고
    • The impact of tumor expression of erythropoietin receptors and erythropoietin on clinical outcome of esophageal cancer patients treated with chemoradiation
    • Rades D, Golke H, Schild SE, Kilic E. The impact of tumor expression of erythropoietin receptors and erythropoietin on clinical outcome of esophageal cancer patients treated with chemoradiation. Int J Radiat Oncol Biol Phys. 2008;71(1):152-159.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , Issue.1 , pp. 152-159
    • Rades, D.1    Golke, H.2    Schild, S.E.3    Kilic, E.4
  • 242
    • 78649515959 scopus 로고    scopus 로고
    • Erythropoietin is involved in angiogenesis in human primary melanoma
    • Ribatti D, Nico B, Perra MT, et al. Erythropoietin is involved in angiogenesis in human primary melanoma. Int J Exp Pathol. 2010; 91(6):495-499.
    • (2010) Int J Exp Pathol , vol.91 , Issue.6 , pp. 495-499
    • Ribatti, D.1    Nico, B.2    Perra, M.T.3
  • 243
    • 79551623759 scopus 로고    scopus 로고
    • High expression levels of erythropoietin and its receptor are not correlated with shorter survival in human glioblastoma
    • Brunotte J, Bock HC, Bruck W, Hemmerlein B, Strik H. High expression levels of erythropoietin and its receptor are not correlated with shorter survival in human glioblastoma. Exp Ther Med. 2011;2(2): 295-299.
    • (2011) Exp Ther Med , vol.2 , Issue.2 , pp. 295-299
    • Brunotte, J.1    Bock, H.C.2    Bruck, W.3    Hemmerlein, B.4    Strik, H.5
  • 244
    • 42949130784 scopus 로고    scopus 로고
    • Survival and erythropoietin receptor protein in tumours from patients randomly treated with rhEPO for palliative care
    • Lonnroth C, Svensson M, Wang W, et al. Survival and erythropoietin receptor protein in tumours from patients randomly treated with rhEPO for palliative care. Med Oncol. 2008;25(1):22-29.
    • (2008) Med Oncol , vol.25 , Issue.1 , pp. 22-29
    • Lonnroth, C.1    Svensson, M.2    Wang, W.3
  • 245
    • 34247843062 scopus 로고    scopus 로고
    • De novo erythropoietin receptor (EPO-R. expression in human neoplastic glial cells decreases with grade of malignancy but is favourably associated with patient survival
    • Mittelbronn M, Capper D, Bunz B, et al. De novo erythropoietin receptor (EPO-R. expression in human neoplastic glial cells decreases with grade of malignancy but is favourably associated with patient survival. Neuropathol Appl Neurobiol. 2007;33(3):299-307.
    • (2007) Neuropathol Appl Neurobiol , vol.33 , Issue.3 , pp. 299-307
    • Mittelbronn, M.1    Capper, D.2    Bunz, B.3
  • 246
    • 35448945986 scopus 로고    scopus 로고
    • Erythropoietin and its receptor in breast cancer: Correlation with steroid receptors and outcome
    • Pelekanou V, Kampa M, Kafousi M, et al. Erythropoietin and its receptor in breast cancer: correlation with steroid receptors and outcome. Cancer Epidemiol Biomarkers Prev. 2007;16(10):2016-2023.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , Issue.10 , pp. 2016-2023
    • Pelekanou, V.1    Kampa, M.2    Kafousi, M.3
  • 247
    • 34548161623 scopus 로고    scopus 로고
    • Expression of erythropoietin and its receptor in neuroblastomas
    • Sartelet H, Fabre M, Castaing M, et al. Expression of erythropoietin and its receptor in neuroblastomas. Cancer. 2007;110(5):1096-1106.
    • (2007) Cancer , vol.110 , Issue.5 , pp. 1096-1106
    • Sartelet, H.1    Fabre, M.2    Castaing, M.3
  • 249
  • 250
    • 55249083610 scopus 로고    scopus 로고
    • Specificity of immunoreactions: The importance of testing specificity in each method
    • Lorincz A, Nusser Z. Specificity of immunoreactions: the importance of testing specificity in each method. J Neurosci. 2008;28(37): 9083-9086.
    • (2008) J Neurosci , vol.28 , Issue.37 , pp. 9083-9086
    • Lorincz, A.1    Nusser, Z.2
  • 251
    • 2342624088 scopus 로고    scopus 로고
    • Pitfalls in diagnostic immunohistology
    • Leong AS. Pitfalls in diagnostic immunohistology. Adv Anat Pathol. 2004;11(2):86-93.
    • (2004) Adv Anat Pathol , vol.11 , Issue.2 , pp. 86-93
    • Leong, A.S.1
  • 253
    • 58149089976 scopus 로고    scopus 로고
    • A guide to the perplexed on the specificity of antibodies
    • Saper CB. A guide to the perplexed on the specificity of antibodies. J Histochem Cytochem. 2009;57(1):1-5.
    • (2009) J Histochem Cytochem , vol.57 , Issue.1 , pp. 1-5
    • Saper, C.B.1
  • 254
    • 57449097579 scopus 로고    scopus 로고
    • Is my antibody-staining specific? How to deal with pitfalls of immunohistochemistry
    • Fritschy JM. Is my antibody-staining specific? How to deal with pitfalls of immunohistochemistry. Eur J Neurosci. 2008;28(12): 2365-2370.
    • (2008) Eur J Neurosci , vol.28 , Issue.12 , pp. 2365-2370
    • Fritschy, J.M.1
  • 255
    • 84866752225 scopus 로고    scopus 로고
    • Absence of functional Epo receptors in normal and cancerous human tissues and cell lines
    • Elliott S, Swift S, Busse L, Rossi J, McCaffery I. Absence of functional Epo receptors in normal and cancerous human tissues and cell lines. Blood. 2011;118(21):3169.
    • (2011) Blood , vol.118 , Issue.21 , pp. 3169
    • Elliott, S.1    Swift, S.2    Busse, L.3    Rossi, J.4    McCaffery, I.5
  • 256
    • 84859212953 scopus 로고    scopus 로고
    • Analysis of cell surface erythropoietin receptor (EpoR) expression and function in human epithelial tumor tissues [abstract]
    • Abstr 11104
    • Rossi J, McCaffery I, Paweletz K, et al. Analysis of cell surface erythropoietin receptor (EpoR) expression and function in human epithelial tumor tissues [abstract]. J Clin Oncol. 2009;27(15S):Abstr 11104.
    • (2009) J Clin Onco , vol.27 , Issue.15 S
    • Rossi, J.1    McCaffery, I.2    Paweletz, K.3
  • 257
    • 0033982421 scopus 로고    scopus 로고
    • Quantitative expression of erythropoietin receptor (EPO-R) on acute leukaemia cells: Relationships between the amount of EPO-R and CD phenotypes, in vitro proliferative response, the amount of other cytokine receptors and clinical prognosis. Japan Adult Leukaemia Study Group
    • Takeshita A, Shinjo K, Higuchi M, et al. Quantitative expression of erythropoietin receptor (EPO-R) on acute leukaemia cells: relationships between the amount of EPO-R and CD phenotypes, in vitro proliferative response, the amount of other cytokine receptors and clinical prognosis. Japan Adult Leukaemia Study Group. Br J Haematol. 2000;108(1):55-63.
    • (2000) Br J Haematol , vol.108 , Issue.1 , pp. 55-63
    • Takeshita, A.1    Shinjo, K.2    Higuchi, M.3
  • 258
    • 34250710896 scopus 로고    scopus 로고
    • Expression of erythropoietin receptor and in vitro functional effects of epoetins in B-cell malignancies
    • Kokhaei P, Abdalla AO, Hansson L, et al. Expression of erythropoietin receptor and in vitro functional effects of epoetins in B-cell malignancies. Clin Cancer Res. 2007;13(12):3536-3544.
    • (2007) Clin Cancer Res , vol.13 , Issue.12 , pp. 3536-3544
    • Kokhaei, P.1    Abdalla, A.O.2    Hansson, L.3
  • 259
    • 33644970398 scopus 로고    scopus 로고
    • Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models
    • LaMontagne KR, Butler J, Marshall DJ, et al. Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models. Mol Cancer Ther. 2006;5(2):347-355.
    • (2006) Mol Cancer Ther , vol.5 , Issue.2 , pp. 347-355
    • Lamontagne, K.R.1    Butler, J.2    Marshall, D.J.3
  • 260
    • 1342322683 scopus 로고    scopus 로고
    • Effect of haemopoietic growth factors on cancer cell lines and their role in chemosensitivity
    • Liu WM, Powles T, Shamash J, Propper D, Oliver T, Joel S. Effect of haemopoietic growth factors on cancer cell lines and their role in chemosensitivity. Oncogene. 2004;23(4):981-990.
    • (2004) Oncogene , vol.23 , Issue.4 , pp. 981-990
    • Liu, W.M.1    Powles, T.2    Shamash, J.3    Propper, D.4    Oliver, T.5    Joel, S.6
  • 261
    • 0023635833 scopus 로고
    • Effects of granulocyte-macrophage colony-stimulating factor and erythropoietin on leukemic erythroid colony formation in human early erythroblastic leukemias
    • Mitjavila MT, Villeval JL, Cramer P, et al. Effects of granulocyte-macrophage colony-stimulating factor and erythropoietin on leukemic erythroid colony formation in human early erythroblastic leukemias. Blood. 1987;70(4):965-973.
    • (1987) Blood , vol.70 , Issue.4 , pp. 965-973
    • Mitjavila, M.T.1    Villeval, J.L.2    Cramer, P.3
  • 262
    • 0023692405 scopus 로고
    • Growth of clonogenic myeloblastic leukemic cells in the presence of human recombinant erythropoietin in addition to various human recombinant hematopoietic growth factors
    • Asano Y, Okamura S, Shibuya T, Harada M, Niho Y. Growth of clonogenic myeloblastic leukemic cells in the presence of human recombinant erythropoietin in addition to various human recombinant hematopoietic growth factors. Blood. 1988;72(5):1682-1686.
    • (1988) Blood , vol.72 , Issue.5 , pp. 1682-1686
    • Asano, Y.1    Okamura, S.2    Shibuya, T.3    Harada, M.4    Niho, Y.5
  • 263
    • 0035195559 scopus 로고    scopus 로고
    • Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia
    • Kolonics A, Apati A, Nahajevszky S, Gati R, Brozik A, Magocsi M. Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia. Haematologia. 2001;31(2):125-138.
    • (2001) Haematologia , vol.31 , Issue.2 , pp. 125-138
    • Kolonics, A.1    Apati, A.2    Nahajevszky, S.3    Gati, R.4    Brozik, A.5    Magocsi, M.6
  • 264
    • 15844364757 scopus 로고    scopus 로고
    • Autocrine regulation of erythropoietin gene expression in human hepatocellular carcinoma cells
    • Ohigashi T, Yoshioka K, Fisher JW. Autocrine regulation of erythropoietin gene expression in human hepatocellular carcinoma cells. Life Sci. 1996;58(5):421-427.
    • (1996) Life Sci , vol.58 , Issue.5 , pp. 421-427
    • Ohigashi, T.1    Yoshioka, K.2    Fisher, J.W.3
  • 265
    • 0033852337 scopus 로고    scopus 로고
    • Erythropoietin stimulates proliferation of human renal carcinoma cells
    • Westenfelder C, Baranowski RL. Erythropoietin stimulates proliferation of human renal carcinoma cells. Kidney Int. 2000;58(2):647-657.
    • (2000) Kidney Int , vol.58 , Issue.2 , pp. 647-657
    • Westenfelder, C.1    Baranowski, R.L.2
  • 266
    • 0024503246 scopus 로고
    • Identification and analysis of human erythropoietin receptors on a factor-dependent cell line, TF-1
    • Kitamura T, Tojo A, Kuwaki T, et al. Identification and analysis of human erythropoietin receptors on a factor-dependent cell line, TF-1. Blood. 1989;73(2):375-380.
    • (1989) Blood , vol.73 , Issue.2 , pp. 375-380
    • Kitamura, T.1    Tojo, A.2    Kuwaki, T.3
  • 267
    • 0024410538 scopus 로고
    • KU 812: A pluripotent human cell line with spontaneous erythroid terminal maturation
    • Nakazawa M, Mitjavila MT, Debili N, et al. KU 812: a pluripotent human cell line with spontaneous erythroid terminal maturation. Blood. 1989;73(7):2003-2013.
    • (1989) Blood , vol.73 , Issue.7 , pp. 2003-2013
    • Nakazawa, M.1    Mitjavila, M.T.2    Debili, N.3
  • 268
    • 0024416070 scopus 로고
    • Receptor-ligand interaction: A new method for determining binding parameters without a priori assumptions on non-specific binding
    • van Zoelen EJ. Receptor-ligand interaction: a new method for determining binding parameters without a priori assumptions on non-specific binding. Biochem J. 1989;262(2):549-556.
    • (1989) Biochem J , vol.262 , Issue.2 , pp. 549-556
    • van Zoelen, E.J.1
  • 269
    • 33750971445 scopus 로고    scopus 로고
    • Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function
    • Pelletier S, Gingras S, Funakoshi-Tago M, Howell S, Ihle JN. Two domains of the erythropoietin receptor are sufficient for Jak2 binding/activation and function. Mol Cell Biol. 2006;26(22):8527-8538.
    • (2006) Mol Cell Biol , vol.26 , Issue.22 , pp. 8527-8538
    • Pelletier, S.1    Gingras, S.2    Funakoshi-Tago, M.3    Howell, S.4    Ihle, J.N.5
  • 270
    • 23644452448 scopus 로고    scopus 로고
    • Correction of anaemia through the use of darbepoetin alfa improves chemotherapeutic outcome in a murine model of Lewis lung carcinoma
    • Shannon AM, Bouchier-Hayes DJ, Condron CM, Toomey D. Correction of anaemia through the use of darbepoetin alfa improves chemotherapeutic outcome in a murine model of Lewis lung carcinoma. Br J Cancer. 2005;93(2):224-232.
    • (2005) Br J Cancer , vol.93 , Issue.2 , pp. 224-232
    • Shannon, A.M.1    Bouchier-Hayes, D.J.2    Condron, C.M.3    Toomey, D.4
  • 271
    • 58549086379 scopus 로고    scopus 로고
    • Constitutively active erythropoietin receptor expression in breast cancer cells promotes cellular proliferation and migration through a MAP-kinase dependent pathway
    • Fu P, Jiang X, Arcasoy MO. Constitutively active erythropoietin receptor expression in breast cancer cells promotes cellular proliferation and migration through a MAP-kinase dependent pathway. Biochem Biophys Res Commun. 2009;379(3):696-701.
    • (2009) Biochem Biophys Res Commun , vol.379 , Issue.3 , pp. 696-701
    • Fu, P.1    Jiang, X.2    Arcasoy, M.O.3
  • 272
    • 35148857257 scopus 로고    scopus 로고
    • Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression
    • Hardee ME, Cao Y, Fu P, et al. Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression. PloS One 2007;(6):e549.
    • (2007) PloS One , Issue.6
    • Hardee, M.E.1    Cao, Y.2    Fu, P.3
  • 273
    • 33646799126 scopus 로고    scopus 로고
    • Induction of signalling in non-erythroid cells by pharmacological levels of erythropoietin
    • Dunlop EA, Percy MJ, Boland MP, Maxwell AP, Lappin TR. Induction of signalling in non-erythroid cells by pharmacological levels of erythropoietin. Neurodegener Dis. 2006;3(1-2):94-100.
    • (2006) Neurodegener Dis , vol.3 , Issue.1-2 , pp. 94-100
    • Dunlop, E.A.1    Percy, M.J.2    Boland, M.P.3    Maxwell, A.P.4    Lappin, T.R.5
  • 274
    • 33646834778 scopus 로고    scopus 로고
    • Antiapoptotic effects of erythropoietin in differentiated neuroblastoma SH-SY5Y cells require activation of both the STAT5 and AKT signaling pathways
    • Um M, Lodish HF. Antiapoptotic effects of erythropoietin in differentiated neuroblastoma SH-SY5Y cells require activation of both the STAT5 and AKT signaling pathways. J Biol Chem. 2006; 281(9):5648-5656.
    • (2006) J Biol Chem , vol.281 , Issue.9 , pp. 5648-5656
    • Um, M.1    Lodish, H.F.2
  • 275
    • 78249236544 scopus 로고    scopus 로고
    • Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation
    • Liang K, Esteva FJ, Albarracin C, et al. Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation. Cancer Cell. 2010;18(5):423-435.
    • (2010) Cancer Cell , vol.18 , Issue.5 , pp. 423-435
    • Liang, K.1    Esteva, F.J.2    Albarracin, C.3
  • 276
    • 72049084476 scopus 로고    scopus 로고
    • Role of erythropoietin receptor expression in malignant melanoma
    • Mirmohammadsadegh A, Marini A, Gustrau A, et al. Role of erythropoietin receptor expression in malignant melanoma. J Invest Dermatol. 2010;130(1):201-210.
    • (2010) J Invest Dermatol , vol.130 , Issue.1 , pp. 201-210
    • Mirmohammadsadegh, A.1    Marini, A.2    Gustrau, A.3
  • 277
    • 0036318603 scopus 로고    scopus 로고
    • Functional significance of erythropoietin receptor expression in breast cancer
    • Arcasoy MO, Amin K, Karayal AF, et al. Functional significance of erythropoietin receptor expression in breast cancer. Lab Invest. 2002;82(7):911-918.
    • (2002) Lab Invest , vol.82 , Issue.7 , pp. 911-918
    • Arcasoy, M.O.1    Amin, K.2    Karayal, A.F.3
  • 278
    • 40849131157 scopus 로고    scopus 로고
    • Erythropoietin stimulates cancer cell migration and activates RhoA protein through a mitogen-activated protein kinase/extracellular signal-regulated kinase-dependent mechanism
    • Hamadmad SN, Hohl RJ. Erythropoietin stimulates cancer cell migration and activates RhoA protein through a mitogen-activated protein kinase/extracellular signal-regulated kinase-dependent mechanism. J Pharmacol Exp Ther. 2008;324(3):1227-1233.
    • (2008) J Pharmacol Exp Ther , vol.324 , Issue.3 , pp. 1227-1233
    • Hamadmad, S.N.1    Hohl, R.J.2
  • 279
    • 84866752972 scopus 로고    scopus 로고
    • Janus kinase (JAK) 2 potency and selectivity assessment of small molecules: Widely used AG490 inhibitor is neither potent nor selective for JAK2
    • Sinclair A, Archibeque I, Zhan J, et al. Janus kinase (JAK) 2 potency and selectivity assessment of small molecules: widely used AG490 inhibitor is neither potent nor selective for JAK2. Blood. 2011;118(21):4780.
    • (2011) Blood , vol.118 , Issue.21 , pp. 4780
    • Sinclair, A.1    Archibeque, I.2    Zhan, J.3
  • 280
    • 2042503119 scopus 로고    scopus 로고
    • Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells
    • Kirken RA, Erwin RA, Taub D, et al. Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells. J Leuke Biol. 1999;65(6):891-899.
    • (1999) J Leuke Biol , vol.65 , Issue.6 , pp. 891-899
    • Kirken, R.A.1    Erwin, R.A.2    Taub, D.3
  • 281
    • 0025833550 scopus 로고
    • Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases
    • Gazit A, Osherov N, Posner I, et al. Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J Med Chem. 1991;34(6):1896-1907.
    • (1991) J Med Chem , vol.34 , Issue.6 , pp. 1896-1907
    • Gazit, A.1    Osherov, N.2    Posner, I.3
  • 282
    • 3042604812 scopus 로고    scopus 로고
    • Tyrphostins are inhibitors of guanylyl and adenylyl cyclases
    • Jaleel M, Shenoy AR, Visweswariah SS. Tyrphostins are inhibitors of guanylyl and adenylyl cyclases. Biochem. 2004;43(25): 8247-8255.
    • (2004) Biochem , vol.43 , Issue.25 , pp. 8247-8255
    • Jaleel, M.1    Shenoy, A.R.2    Visweswariah, S.S.3
  • 283
    • 0028227405 scopus 로고
    • Tyrphostin induced growth inhibition: Correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia
    • Kaur G, Gazit A, Levitzki A, Stowe E, Cooney DA, Sausville EA. Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia. Anticancer Drugs. 1994;5(2):213-222.
    • (1994) Anticancer Drugs , vol.5 , Issue.2 , pp. 213-222
    • Kaur, G.1    Gazit, A.2    Levitzki, A.3    Stowe, E.4    Cooney, D.A.5    Sausville, E.A.6
  • 284
    • 33646236934 scopus 로고    scopus 로고
    • Erythropoietin fails to interfere with the antiproliferative and cytotoxic effects of antitumor drugs
    • Gewirtz DA, Di X, Walker TD, Sawyer ST. Erythropoietin fails to interfere with the antiproliferative and cytotoxic effects of antitumor drugs. Clin Cancer Res. 2006;12(7 Pt 1):2232-2238.
    • (2006) Clin Cancer Res , vol.12 , Issue.7 Pt 1 , pp. 2232-2238
    • Gewirtz, D.A.1    Di, X.2    Walker, T.D.3    Sawyer, S.T.4
  • 285
    • 73349108446 scopus 로고    scopus 로고
    • Examining the involvement of erythropoiesis-stimulating agents in tumor proliferation (erythropoietin receptors, receptor binding, signal transduction), angiogenesis, and venous thromboembolic events
    • Fandrey J, Dicato M. Examining the involvement of erythropoiesis-stimulating agents in tumor proliferation (erythropoietin receptors, receptor binding, signal transduction), angiogenesis, and venous thromboembolic events. Oncologist. 2009;14 Suppl 1:34-42.
    • (2009) Oncologist , Issue.14 SUPPL 1 , pp. 34-42
    • Fandrey, J.1    Dicato, M.2
  • 286
    • 0034816489 scopus 로고    scopus 로고
    • Low doses of EPO activate MAP kinases but not JAK2-STAT5 in rat vascular smooth muscle cells
    • Ammarguellat F, Llovera M, Kelly PA, Goffin V. Low doses of EPO activate MAP kinases but not JAK2-STAT5 in rat vascular smooth muscle cells. Biochem Biophys Res Commun. 2001;284(4): 1031-1038.
    • (2001) Biochem Biophys Res Commun , vol.284 , Issue.4 , pp. 1031-1038
    • Ammarguellat, F.1    Llovera, M.2    Kelly, P.A.3    Goffin, V.4
  • 287
    • 35148857257 scopus 로고    scopus 로고
    • Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression
    • Hardee ME, Cao Y, Fu P, et al. Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression. PloS One. 2007;(6):e549.
    • (2007) PloS One , Issue.6
    • Hardee, M.E.1    Cao, Y.2    Fu, P.3
  • 288
    • 28244458421 scopus 로고    scopus 로고
    • Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia
    • Lester RD, Jo M, Campana WM, Gonias SL. Erythropoietin promotes MCF-7 breast cancer cell migration by an ERK/mitogen-activated protein kinase-dependent pathway and is primarily responsible for the increase in migration observed in hypoxia. J Biol Chem. 2005;280(47):39273-39277.
    • (2005) J Biol Chem , vol.280 , Issue.47 , pp. 39273-39277
    • Lester, R.D.1    Jo, M.2    Campana, W.M.3    Gonias, S.L.4
  • 289
    • 0034658111 scopus 로고    scopus 로고
    • Pharmaceutical intervention in the JAK/STAT signaling pathway
    • Seidel HM, Lamb P, Rosen J. Pharmaceutical intervention in the JAK/STAT signaling pathway. Oncogene. 2000;19(21):2645-2656.
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2645-2656
    • Seidel, H.M.1    Lamb, P.2    Rosen, J.3
  • 290
    • 79952824314 scopus 로고    scopus 로고
    • JAK/STAT pathways in cytokine signaling and myeloproliferative disorders: Approaches for targeted therapies
    • Jatiani SS, Baker SJ, Silverman LR, Premkumar RE. JAK/STAT pathways in cytokine signaling and myeloproliferative disorders: approaches for targeted therapies. Genes Cancer. 2010;1(10):979-993.
    • (2010) Genes Cancer , vol.1 , Issue.10 , pp. 979-993
    • Jatiani, S.S.1    Baker, S.J.2    Silverman, L.R.3    Premkumar, R.E.4
  • 291
    • 0032076542 scopus 로고    scopus 로고
    • Jak2 is essential for signaling through a variety of cytokine receptors
    • Parganas E, Wang D, Stravopodis D, et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell. 1998;93(3):385-395.
    • (1998) Cell , vol.93 , Issue.3 , pp. 385-395
    • Parganas, E.1    Wang, D.2    Stravopodis, D.3
  • 292
    • 77950809571 scopus 로고    scopus 로고
    • Erythropoietin receptor in ovarian cancer cells - Letter
    • Swift S, Elliott S, Sinclair A, Begley CG. Erythropoietin receptor in ovarian cancer cells - Letter. Mol Cancer Ther. 2010;9(4):1070-1071.
    • (2010) Mol Cancer Ther , vol.9 , Issue.4 , pp. 1070-1071
    • Swift, S.1    Elliott, S.2    Sinclair, A.3    Begley, C.G.4
  • 293
    • 79952236601 scopus 로고    scopus 로고
    • LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis
    • Hsu RY, Chan CH, Spicer JD, et al. LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. Cancer Res. 2011;71(5): 1989-1998.
    • (2011) Cancer Res , vol.71 , Issue.5 , pp. 1989-1998
    • Hsu, R.Y.1    Chan, C.H.2    Spicer, J.D.3
  • 294
    • 69249176159 scopus 로고    scopus 로고
    • Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells
    • Doan HQ, Bowen KA, Jackson LA, Evers BM. Toll-like receptor 4 activation increases Akt phosphorylation in colon cancer cells. Anticancer Res. 2009;29(7):2473-2478.
    • (2009) Anticancer Res , vol.29 , Issue.7 , pp. 2473-2478
    • Doan, H.Q.1    Bowen, K.A.2    Jackson, L.A.3    Evers, B.M.4
  • 295
    • 0030988797 scopus 로고    scopus 로고
    • Recombinant human albumin in cell culture: Evaluation of growth-promoting potential for NRK and SCC-9 cells in vitro
    • Keenan J, Dooley M, Pearson D, Clynes M. Recombinant human albumin in cell culture: evaluation of growth-promoting potential for NRK and SCC-9 cells in vitro. Cytotechnology. 1996;24(243):252.
    • (1996) Cytotechnology , vol.24 , Issue.243 , pp. 252
    • Keenan, J.1    Dooley, M.2    Pearson, D.3    Clynes, M.4
  • 296
    • 44349158320 scopus 로고    scopus 로고
    • IGF-I binding to the IGF-I receptor is affected by contaminants in commercial BSA: The contaminants are proteins with IGF-I binding properties
    • Slaaby R, Andersen AS, Brandt J. IGF-I binding to the IGF-I receptor is affected by contaminants in commercial BSA: the contaminants are proteins with IGF-I binding properties. Growth Horm IGF Res. 2008;18(4):267-274.
    • (2008) Growth Horm IGF Res , vol.18 , Issue.4 , pp. 267-274
    • Slaaby, R.1    Andersen, A.S.2    Brandt, J.3
  • 297
    • 0021474728 scopus 로고
    • Receptor-dependent and independent degradation of insulin by isolated swine adipocytes at 37 C
    • Etherton TD, Chung CS, Wiggins JP. Receptor-dependent and independent degradation of insulin by isolated swine adipocytes at 37 C. J Anim Sci. 1984;59(2):366-375.
    • (1984) J Anim Sci , vol.59 , Issue.2 , pp. 366-375
    • Etherton, T.D.1    Chung, C.S.2    Wiggins, J.P.3
  • 298
    • 79955671148 scopus 로고    scopus 로고
    • EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma
    • Blair KJ, Kiang A, Wang-Rodriguez J, Yu MA, Doherty JK, Ongkeko WM. EGF and bFGF promote invasion that is modulated by PI3/Akt kinase and Erk in vestibular schwannoma. Otol Neurotol. 2011;32(2):308-314.
    • (2011) Otol Neurotol , vol.32 , Issue.2 , pp. 308-314
    • Blair, K.J.1    Kiang, A.2    Wang-Rodriguez, J.3    Yu, M.A.4    Doherty, J.K.5    Ongkeko, W.M.6
  • 299
    • 52949105368 scopus 로고    scopus 로고
    • Erythropoietin augments survival of glioma cells after radiation and temozolomide
    • Hassouna I, Sperling S, Kim E, et al. Erythropoietin augments survival of glioma cells after radiation and temozolomide. Int J Radiat Oncol Biol Phys. 2008;72(3):927-934.
    • (2008) Int J Radiat Oncol Biol Phys , vol.72 , Issue.3 , pp. 927-934
    • Hassouna, I.1    Sperling, S.2    Kim, E.3
  • 300
    • 33644970398 scopus 로고    scopus 로고
    • Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models
    • LaMontagne KR, Butler J, Marshall DJ, et al. Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models. Mol Cancer Ther. 2006;5(2):347-355.
    • (2006) Mol Cancer Ther , vol.5 , Issue.2 , pp. 347-355
    • Lamontagne, K.R.1    Butler, J.2    Marshall, D.J.3
  • 301
    • 0018349105 scopus 로고
    • Stem cell migration induced by erythropoietin or haemolytic anaemia: The effects of actinomycin and endotoxin contamination of erythropoietin preparations
    • Quesenberry P, Levin J, Zuckerman K, Rencricca N, Sullivan R, Tyler W. Stem cell migration induced by erythropoietin or haemolytic anaemia: the effects of actinomycin and endotoxin contamination of erythropoietin preparations. Br J Haematol. 1979;41(2):253-269.
    • (1979) Br J Haematol , vol.41 , Issue.2 , pp. 253-269
    • Quesenberry, P.1    Levin, J.2    Zuckerman, K.3    Rencricca, N.4    Sullivan, R.5    Tyler, W.6
  • 302
    • 0037057521 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion
    • Harmey JH, Bucana CD, Lu W, et al. Lipopolysaccharide-induced metastatic growth is associated with increased angiogenesis, vascular permeability and tumor cell invasion. Int J Cancer. 2002;101(5):415-422.
    • (2002) Int J Cancer , vol.101 , Issue.5 , pp. 415-422
    • Harmey, J.H.1    Bucana, C.D.2    Lu, W.3
  • 303
    • 66149129910 scopus 로고    scopus 로고
    • Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system
    • Killeen SD, Wang JH, Andrews EJ, Redmond HP. Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-kappaB-dependent activation of the urokinase plasminogen activator system. Br J Cancer. 2009;100(10):1589-1602.
    • (2009) Br J Cancer , vol.100 , Issue.10 , pp. 1589-1602
    • Killeen, S.D.1    Wang, J.H.2    Andrews, E.J.3    Redmond, H.P.4
  • 304
    • 0037438340 scopus 로고    scopus 로고
    • Endotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism
    • Wang JH, Manning BJ, Wu QD, Blankson S, Bouchier-Hayes D, Redmond HP. Endotoxin/lipopolysaccharide activates NF-kappa B and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism. J Immunol. 2003;170(2):795-804.
    • (2003) J Immunol , vol.170 , Issue.2 , pp. 795-804
    • Wang, J.H.1    Manning, B.J.2    Wu, Q.D.3    Blankson, S.4    Bouchier-Hayes, D.5    Redmond, H.P.6
  • 305
    • 17644420642 scopus 로고    scopus 로고
    • Effects of recombinant human erythropoietin on the growth of various human tumor cells
    • Sugawa M, Fukui H. Effects of recombinant human erythropoietin on the growth of various human tumor cells. Biotherapy. 2005; 19(2):181-196.
    • (2005) Biotherapy , vol.19 , Issue.2 , pp. 181-196
    • Sugawa, M.1    Fukui, H.2
  • 306
    • 0026754335 scopus 로고
    • Effects of recombinant human erythropoietin on clonogenic growth of primary human tumour specimens in vitro
    • Bauer E, Danhauser-Riedl S, De RW, et al. Effects of recombinant human erythropoietin on clonogenic growth of primary human tumour specimens in vitro. Eur J Cancer. 1992;28A(10):1769.
    • (1992) Eur J Cancer , vol.28 A , Issue.10 , pp. 1769
    • Bauer, E.1    Danhauser-Riedl, S.2    De, R.W.3
  • 307
    • 77954680872 scopus 로고    scopus 로고
    • Limitations of a murine transgenic breast cancer model for studies of erythropoietin-induced tumor progression
    • Miller CP, Valliant-Saunders K, Blau CA. Limitations of a murine transgenic breast cancer model for studies of erythropoietin-induced tumor progression. Clin Transl Oncol. 2010;3(3):176-180.
    • (2010) Clin Transl Oncol , vol.3 , Issue.3 , pp. 176-180
    • Miller, C.P.1    Valliant-Saunders, K.2    Blau, C.A.3
  • 308
    • 17744398006 scopus 로고    scopus 로고
    • Inhibition of erythropoietin signalling destroys xenografts of ovarian and uterine cancers in nude mice
    • Yasuda Y, Musha T, Tanaka H, et al. Inhibition of erythropoietin signalling destroys xenografts of ovarian and uterine cancers in nude mice. Br J Cancer. 2001;84(6):836-843.
    • (2001) Br J Cancer , vol.84 , Issue.6 , pp. 836-843
    • Yasuda, Y.1    Musha, T.2    Tanaka, H.3
  • 309
    • 0018357951 scopus 로고
    • Regression of a transplanted guinea pig hepatoma after intralesional injection of an emulsified mixture of endotoxin and mycobacterial sulfolipid
    • Yarkoni E, Goren MB, Rapp HJ. Regression of a transplanted guinea pig hepatoma after intralesional injection of an emulsified mixture of endotoxin and mycobacterial sulfolipid. Infect Immun. 1979; 24(2):357-362.
    • (1979) Infect Immun , vol.24 , Issue.2 , pp. 357-362
    • Yarkoni, E.1    Goren, M.B.2    Rapp, H.J.3
  • 311
    • 0029044765 scopus 로고
    • The cytokine receptor repertoire specifies autocrine growth factor production in factor-dependent cells
    • Rasko JE, Metcalf D, Gough NM, Begley CG. The cytokine receptor repertoire specifies autocrine growth factor production in factor-dependent cells. Exp Hematol. 1995;23(5):453-460.
    • (1995) Exp Hematol , vol.23 , Issue.5 , pp. 453-460
    • Rasko, J.E.1    Metcalf, D.2    Gough, N.M.3    Begley, C.G.4
  • 312
    • 39749119833 scopus 로고    scopus 로고
    • Recombinant erythropoietin differently affects proliferation of mesothelioma cells but not sensitivity to cisplatin and pemetrexed
    • Palumbo C, Battisti S, Carbone D, et al. Recombinant erythropoietin differently affects proliferation of mesothelioma cells but not sensitivity to cisplatin and pemetrexed. Cancer Chemother Pharmacol. 2008;61(5):893-901.
    • (2008) Cancer Chemother Pharmacol , vol.61 , Issue.5 , pp. 893-901
    • Palumbo, C.1    Battisti, S.2    Carbone, D.3
  • 313
    • 4444225002 scopus 로고    scopus 로고
    • Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells
    • Acs G, Chen M, Xu X, Acs P, Verma A, Koch CJ. Autocrine erythropoietin signaling inhibits hypoxia-induced apoptosis in human breast carcinoma cells. Cancer Lett. 2004;214(2):243-251.
    • (2004) Cancer Lett , vol.214 , Issue.2 , pp. 243-251
    • Acs, G.1    Chen, M.2    Xu, X.3    Acs, P.4    Verma, A.5    Koch, C.J.6
  • 315
    • 0022492806 scopus 로고
    • Schooley J, Eastment C. Erythropoietin, an autocrine regulator? Serum-free production of erythropoietin by cloned erythroid cell lines
    • Hankins WD
    • Hankins WD, Schooley J, Eastment C. Erythropoietin, an autocrine regulator? Serum-free production of erythropoietin by cloned erythroid cell lines. Blood. 1986;68(1):263-268.
    • (1986) Blood , vol.68 , Issue.1 , pp. 263-268
  • 316
    • 0022454175 scopus 로고
    • Purification of murine erythropoietin produced in serum-free cultures of erythroleukemia cells
    • Qian RL, Chin K, Kim JK, Chin HM, Cone J, Hankins WD. Purification of murine erythropoietin produced in serum-free cultures of erythroleukemia cells. Blood. 1986;68(1):258-262.
    • (1986) Blood , vol.68 , Issue.1 , pp. 258-262
    • Qian, R.L.1    Chin, K.2    Kim, J.K.3    Chin, H.M.4    Cone, J.5    Hankins, W.D.6
  • 317
    • 0026048014 scopus 로고
    • Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro
    • Mitjavila MT, Le Couedic JP, Casadevall N. Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro. J Clin lnvest. 1991;88(3):789-797.
    • (1991) J Clin Lnvest , vol.88 , Issue.3 , pp. 789-797
    • Mitjavila, M.T.1    Le Couedic, J.P.2    Casadevall, N.3
  • 318
    • 0022596132 scopus 로고
    • Continuous production of erythropoietin by an established human renal carcinoma cell line: Development of the cell line
    • Sherwood JB, Shouval D. Continuous production of erythropoietin by an established human renal carcinoma cell line: development of the cell line. Proc Natl Acad Sci U S A. 1986;83(1):165-169.
    • (1986) Proc Natl Acad Sci U S A , vol.83 , Issue.1 , pp. 165-169
    • Sherwood, J.B.1    Shouval, D.2
  • 319
    • 0024197354 scopus 로고
    • Production of erythropoietin by an established human renal carcinoma cell line: In vitro and in vivo studies
    • Shouval D, Sherwood JB. Production of erythropoietin by an established human renal carcinoma cell line: in vitro and in vivo studies. Adv Exp Med Biol. 1988;241:319-328.
    • (1988) Adv Exp Med Biol , vol.241 , pp. 319-328
    • Shouval, D.1    Sherwood, J.B.2
  • 320
    • 0016165532 scopus 로고
    • Paraneoplastic erythrocytosis and ectopic erythropoietins
    • Hammond D, Winnick S. Paraneoplastic erythrocytosis and ectopic erythropoietins. Ann N Y Acad Sci. 1974;230:219-227.
    • (1974) Ann N Y Acad Sci , vol.230 , pp. 219-227
    • Hammond, D.1    Winnick, S.2
  • 321
    • 54549113030 scopus 로고    scopus 로고
    • The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer
    • Kaelin WG Jr. The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer. Nat Rev Cancer. 2008;8(11):865-873.
    • (2008) Nat Rev Cancer , vol.8 , Issue.11 , pp. 865-873
    • Kaelin Jr., W.G.1
  • 322
    • 0026603954 scopus 로고
    • Effects of hematopoietic growth factors on malignant nonhematopoietic cells
    • Berdel WE, Danhauser-Riedl S, Oberberg D, Zafferani M. Effects of hematopoietic growth factors on malignant nonhematopoietic cells. Semin Oncol. 1992;19(2 Suppl 4):41-45.
    • (1992) Semin Oncol , vol.19 , Issue.2 SUPPL 4 , pp. 41-45
    • Berdel, W.E.1    Danhauser-Riedl, S.2    Oberberg, D.3    Zafferani, M.4
  • 323
    • 0028589641 scopus 로고
    • Persistent erythropoiesis by myoblast transfer of erythropoietin cDNA
    • Hamamori Y, Samal B, Tian J, Kedes L. Persistent erythropoiesis by myoblast transfer of erythropoietin cDNA. Hum Gene Ther. 1994;5(11):1349-1356.
    • (1994) Hum Gene Ther , vol.5 , Issue.11 , pp. 1349-1356
    • Hamamori, Y.1    Samal, B.2    Tian, J.3    Kedes, L.4
  • 324
    • 0035202033 scopus 로고    scopus 로고
    • In vivo gene electroporation in skeletal muscle with special reference to the duration of gene expression
    • Muramatsu T, Arakawa S, Fukazawa K, et al. In vivo gene electroporation in skeletal muscle with special reference to the duration of gene expression. Int J Mol Med. 2001;7(1):37-42.
    • (2001) Int J Mol Med , vol.7 , Issue.1 , pp. 37-42
    • Muramatsu, T.1    Arakawa, S.2    Fukazawa, K.3
  • 325
    • 80054000495 scopus 로고    scopus 로고
    • Coordinating cell behaviour during blood vessel formation
    • Geudens I, Gerhardt H. Coordinating cell behaviour during blood vessel formation. Development. 2011;138(21):4569-4583.
    • (2011) Development , vol.138 , Issue.21 , pp. 4569-4583
    • Geudens, I.1    Gerhardt, H.2
  • 326
    • 0032824560 scopus 로고    scopus 로고
    • Inactivation of erythropoietin leads to defects in cardiac morphogenesis
    • Wu H, Lee SH, Gao J, Liu X, Iruela-Arispe ML. Inactivation of erythropoietin leads to defects in cardiac morphogenesis. Development. 1999;126(16):3597-3605.
    • (1999) Development , vol.126 , Issue.16 , pp. 3597-3605
    • Wu, H.1    Lee, S.H.2    Gao, J.3    Liu, X.4    Iruela-Arispe, M.L.5
  • 327
    • 7544221404 scopus 로고    scopus 로고
    • The role of erythropoietin in regulating angiogenesis
    • Kertesz N, Wu J, Chen TH, Sucov HM, Wu H. The role of erythropoietin in regulating angiogenesis. Dev Biol. 2004;276(1):101-110.
    • (2004) Dev Biol , vol.276 , Issue.1 , pp. 101-110
    • Kertesz, N.1    Wu, J.2    Chen, T.H.3    Sucov, H.M.4    Wu, H.5
  • 328
    • 0034813202 scopus 로고    scopus 로고
    • Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice
    • Davidoff AM, Ng CY, Brown P, et al. Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice. Clin Cancer Res. 2001;7(9):2870-2879.
    • (2001) Clin Cancer Res , vol.7 , Issue.9 , pp. 2870-2879
    • Davidoff, A.M.1    Ng, C.Y.2    Brown, P.3
  • 329
    • 33746781732 scopus 로고    scopus 로고
    • Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis
    • DePalma M, Naldini L. Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis. Biochim Biophys Acta. 2006;1766(1):159-166.
    • (2006) Biochim Biophys Acta , vol.1766 , Issue.1 , pp. 159-166
    • Depalma, M.1    Naldini, L.2
  • 330
    • 33947281784 scopus 로고    scopus 로고
    • Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells
    • [Erratum, Exp Hematol. 2007;35(7):1153-1161]
    • Zwezdaryk KJ, Coffelt SB, Figueroa YG, et al. Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells. Exp Hematol. 2007;35(4):640-652; [Erratum, Exp Hematol. 2007;35(7):1153-1161].
    • (2007) Exp Hematol , vol.35 , Issue.4 , pp. 640-652
    • Zwezdaryk, K.J.1    Coffelt, S.B.2    Figueroa, Y.G.3
  • 331
    • 57549111654 scopus 로고    scopus 로고
    • Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages
    • Hao Q, Liu JR, Pappu R, et al. Contribution of bone marrow-derived cells associated with brain angiogenesis is primarily through leukocytes and macrophages. Arterioscler Thromb Vasc Biol. 2008; 28(12):2151-2157.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.12 , pp. 2151-2157
    • Hao, Q.1    Liu, J.R.2    Pappu, R.3
  • 333
    • 70449447803 scopus 로고    scopus 로고
    • Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction
    • Perry TE, Song M, Despres DJ, et al. Bone marrow-derived cells do not repair endothelium in a mouse model of chronic endothelial cell dysfunction. Cardiovasc Res. 2009;84(2):317-325.
    • (2009) Cardiovasc Res , vol.84 , Issue.2 , pp. 317-325
    • Perry, T.E.1    Song, M.2    Despres, D.J.3
  • 334
    • 44349188724 scopus 로고    scopus 로고
    • Adult bone marrow-derived cells do not acquire functional attributes of cardiomyocytes when transplanted into peri-infarct myocardium
    • Scherschel JA, Soonpaa MH, Srour EF, Field LJ, Rubart M. Adult bone marrow-derived cells do not acquire functional attributes of cardiomyocytes when transplanted into peri-infarct myocardium. Mol Ther. 2008;16(6):1129-1137.
    • (2008) Mol Ther , vol.16 , Issue.6 , pp. 1129-1137
    • Scherschel, J.A.1    Soonpaa, M.H.2    Srour, E.F.3    Field, L.J.4    Rubart, M.5
  • 335
    • 4444311008 scopus 로고    scopus 로고
    • Genetically tagging endothelial cells in vivo: Bone marrow-derived cells do not contribute to tumor endothelium
    • Gothert JR, Gustin SE, van Eekelen JA, et al. Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium. Blood. 2004;104(6):1769-1777.
    • (2004) Blood , vol.104 , Issue.6 , pp. 1769-1777
    • Gothert, J.R.1    Gustin, S.E.2    van Eekelen, J.A.3
  • 336
    • 1042291185 scopus 로고    scopus 로고
    • Bone marrow-derived cells do not incorporate into the adult growing vasculature
    • Ziegelhoeffer T, Fernandez B, Kostin S, et al. Bone marrow-derived cells do not incorporate into the adult growing vasculature. Circ Res. 2004;94(2):230-238.
    • (2004) Circ Res , vol.94 , Issue.2 , pp. 230-238
    • Ziegelhoeffer, T.1    Fernandez, B.2    Kostin, S.3
  • 337
    • 1242352415 scopus 로고    scopus 로고
    • Recombinant human erythropoietin induces intussusceptive microvascular growth in vivo
    • Crivellato E, Nico B, Vacca A, Djonov V, Presta M, Ribatti D. Recombinant human erythropoietin induces intussusceptive microvascular growth in vivo. Leukemia. 2004;18(2):331-336.
    • (2004) Leukemia , vol.18 , Issue.2 , pp. 331-336
    • Crivellato, E.1    Nico, B.2    Vacca, A.3    Djonov, V.4    Presta, M.5    Ribatti, D.6
  • 339
    • 0142187248 scopus 로고    scopus 로고
    • Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin
    • Bahlmann FH, DeGroot K, Duckert T, et al. Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin. Kidney Int. 2003;64(5):1648-1652.
    • (2003) Kidney Int , vol.64 , Issue.5 , pp. 1648-1652
    • Bahlmann, F.H.1    Degroot, K.2    Duckert, T.3
  • 340
    • 4344626952 scopus 로고    scopus 로고
    • Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure
    • Bahlmann FH, Song R, Boehm SM, et al. Low-dose therapy with the long-acting erythropoietin analogue darbepoetin alpha persistently activates endothelial Akt and attenuates progressive organ failure. Circulation. 2004;110(8):1006-1012.
    • (2004) Circulation , vol.110 , Issue.8 , pp. 1006-1012
    • Bahlmann, F.H.1    Song, R.2    Boehm, S.M.3
  • 341
    • 0042738942 scopus 로고    scopus 로고
    • Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization
    • Heeschen C, Aicher A, Lehmann R, et al. Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization. Blood. 2003;102(4):1340-1346.
    • (2003) Blood , vol.102 , Issue.4 , pp. 1340-1346
    • Heeschen, C.1    Aicher, A.2    Lehmann, R.3
  • 342
    • 77957784823 scopus 로고    scopus 로고
    • EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors
    • Perrotta S, Cucciolla V, Ferraro M, et al. EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors. PloS One. 2010; 5(8):2010.
    • (2010) PloS One , vol.5 , Issue.8 , pp. 2010
    • Perrotta, S.1    Cucciolla, V.2    Ferraro, M.3
  • 343
    • 0038725471 scopus 로고    scopus 로고
    • CD105 is important for angiogenesis: Evidence and potential applications
    • Duff SE, Li C, Garland JM, Kumar S. CD105 is important for angiogenesis: evidence and potential applications. FASEB J. 2003;17(9):984-992.
    • (2003) FASEB J , vol.17 , Issue.9 , pp. 984-992
    • Duff, S.E.1    Li, C.2    Garland, J.M.3    Kumar, S.4
  • 344
    • 0026063251 scopus 로고
    • Endoglin is expressed on a subpopulation of immature erythroid cells of normal human bone marrow
    • Buhring HJ, Muller CA, Letarte M, et al. Endoglin is expressed on a subpopulation of immature erythroid cells of normal human bone marrow. Leukemia. 1991;5(10):841-847.
    • (1991) Leukemia , vol.5 , Issue.10 , pp. 841-847
    • Buhring, H.J.1    Muller, C.A.2    Letarte, M.3
  • 345
    • 70449591342 scopus 로고    scopus 로고
    • Mobilization effects of G-CSF, GM-CSF, and darbepoetin-alpha for allogeneic peripheral blood stem cell transplantation
    • Kim SN, Moon JH, Kim JG, et al. Mobilization effects of G-CSF, GM-CSF, and darbepoetin-alpha for allogeneic peripheral blood stem cell transplantation. J Clin Apher. 2009;24(5):173-179.
    • (2009) J Clin Apher , vol.24 , Issue.5 , pp. 173-179
    • Kim, S.N.1    Moon, J.H.2    Kim, J.G.3
  • 346
    • 78349233886 scopus 로고    scopus 로고
    • Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): A pilot, randomized, placebo-controlled study
    • Taniguchi N, Sawada T, Matsubara K, et al. Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): a pilot, randomized, placebo-controlled study. Circ J. 2010;74(11):2365-2371.
    • (2010) Circ J , vol.74 , Issue.11 , pp. 2365-2371
    • Taniguchi, N.1    Sawada, T.2    Matsubara, K.3
  • 347
    • 34548663552 scopus 로고    scopus 로고
    • Long-term erythropoietin therapy does not affect endothelial markers, coagulation activation and oxidative stress in haemodialyzed patients
    • Pawlak K, Pawlak D, Mysliwiec M. Long-term erythropoietin therapy does not affect endothelial markers, coagulation activation and oxidative stress in haemodialyzed patients. Thromb Res. 2007;120(6):797-803.
    • (2007) Thromb Res , vol.120 , Issue.6 , pp. 797-803
    • Pawlak, K.1    Pawlak, D.2    Mysliwiec, M.3
  • 348
    • 70349690174 scopus 로고    scopus 로고
    • Bone marrow-derived cells are not involved in reendothelialized endothelium as endothelial cells after simple endothelial denudation in mice
    • Tsuzuki M. Bone marrow-derived cells are not involved in reendothelialized endothelium as endothelial cells after simple endothelial denudation in mice. Basic Res Cardiol. 2009;104(5):601-611.
    • (2009) Basic Res Cardiol , vol.104 , Issue.5 , pp. 601-611
    • Tsuzuki, M.1
  • 349
    • 20144386931 scopus 로고    scopus 로고
    • Contribution of bone marrow-derived endothelial cells to human tumor vasculature
    • Peters BA, Diaz LA, Polyak K, et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med. 2005;11(3):261-262.
    • (2005) Nat Med , vol.11 , Issue.3 , pp. 261-262
    • Peters, B.A.1    Diaz, L.A.2    Polyak, K.3
  • 350
    • 0242667873 scopus 로고    scopus 로고
    • Minor contribution of bone marrow-derived endothelial progenitors to the vascularization of murine gliomas
    • Machein MR, Renninger S, de Lima-Hahn E, Plate KH. Minor contribution of bone marrow-derived endothelial progenitors to the vascularization of murine gliomas. Brain Pathol. 2003;13(4): 582-597.
    • (2003) Brain Pathol , vol.13 , Issue.4 , pp. 582-597
    • Machein, M.R.1    Renninger, S.2    de Lima-Hahn, E.3    Plate, K.H.4
  • 351
    • 0036786352 scopus 로고    scopus 로고
    • Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality
    • Suzuki N, Ohneda O, Takahashi S, et al. Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality. Blood. 2002;100(7):2279-2288.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2279-2288
    • Suzuki, N.1    Ohneda, O.2    Takahashi, S.3
  • 352
    • 0029983017 scopus 로고    scopus 로고
    • Direct effect of erythropoietin on rat vascular smooth-muscle cell via a putative erythropoietin receptor
    • Ammarguellat F, Gogusev J, Drueke TB. Direct effect of erythropoietin on rat vascular smooth-muscle cell via a putative erythropoietin receptor. Nephrol Dial Transplant. 1996;11(4):687-692.
    • (1996) Nephrol Dial Transplant , vol.11 , Issue.4 , pp. 687-692
    • Ammarguellat, F.1    Gogusev, J.2    Drueke, T.B.3
  • 353
    • 0030069085 scopus 로고    scopus 로고
    • Recombinant human erythropoietin does not regulate the expression of endothelin-1 and constitutive nitric oxide synthase in vascular endothelial cells
    • Lopez Ongil SL, Saura M, Lamas S, Rodriguez PM, Rodriguez PD. Recombinant human erythropoietin does not regulate the expression of endothelin-1 and constitutive nitric oxide synthase in vascular endothelial cells. Exp Nephrol. 1996;4(1):37-42.
    • (1996) Exp Nephrol , vol.4 , Issue.1 , pp. 37-42
    • Lopez, O.S.L.1    Saura, M.2    Lamas, S.3    Rodriguez, P.M.4    Rodriguez, P.D.5
  • 354
    • 0036739652 scopus 로고    scopus 로고
    • Erythropoietin does not modify the prothrombotic effect induced by uremic media on endothelial cells
    • Fuste B, az-Ricart M, Cases A, Lopez-Pedret J, Ordinas A, Escolar G. Erythropoietin does not modify the prothrombotic effect induced by uremic media on endothelial cells. Haematologica. 2002;87(9):1006-1008.
    • (2002) Haematologica , vol.87 , Issue.9 , pp. 1006-1008
    • Fuste, B.1    Az-Ricart, M.2    Cases, A.3    Lopez-Pedret, J.4    Ordinas, A.5    Escolar, G.6
  • 355
    • 28644436521 scopus 로고    scopus 로고
    • Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis
    • Hardee ME, Kirkpatrick JP, Shan S, et al. Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis. Br J Cancer. 2005;93(12):1350-1355.
    • (2005) Br J Cancer , vol.93 , Issue.12 , pp. 1350-1355
    • Hardee, M.E.1    Kirkpatrick, J.P.2    Shan, S.3
  • 356
    • 65549157509 scopus 로고    scopus 로고
    • The effects of recombinant human erythropoietin and tamoxifen on growth and angiogenesis of mammary tumor in Sprague-Dawley rat
    • Sairah AK, Rasedee A, Sheikh O, Rozita R, ALHaj N. The effects of recombinant human erythropoietin and tamoxifen on growth and angiogenesis of mammary tumor in Sprague-Dawley rat. Am J Pharmacol Toxicol. 2009;4(1):12-16.
    • (2009) Am J Pharmacol Toxicol , vol.4 , Issue.1 , pp. 12-16
    • Sairah, A.K.1    Rasedee, A.2    Sheikh, O.3    Rozita, R.4    Alhaj, N.5
  • 357
    • 11344268695 scopus 로고    scopus 로고
    • Erythropoietin-induced reduction of hypoxia before and during fractionated irradiation contributes to improvement of radioresponse in human glioma xenografts
    • Pinel S, Barberi-Heyob M, Cohen-Jonathan E, et al. Erythropoietin-induced reduction of hypoxia before and during fractionated irradiation contributes to improvement of radioresponse in human glioma xenografts. Int J Radiat Oncol Biol Phys. 2004;59(1):250-259.
    • (2004) Int J Radiat Oncol Biol Phys , vol.59 , Issue.1 , pp. 250-259
    • Pinel, S.1    Barberi-Heyob, M.2    Cohen-Jonathan, E.3
  • 358
    • 0030017580 scopus 로고    scopus 로고
    • Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA
    • Yamaji R, Okada T, Moriya M, et al. Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA. Eur J Biochem. 1996;239(2):494-500.
    • (1996) Eur J Biochem , vol.239 , Issue.2 , pp. 494-500
    • Yamaji, R.1    Okada, T.2    Moriya, M.3
  • 359
    • 0025297296 scopus 로고
    • Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells
    • Anagnostou A, Lee ES, Kessimian N, Levinson R, Steiner M. Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells. Proc Natl Acad Sci U S A. 1990;87(15):5978-5982.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.15 , pp. 5978-5982
    • Anagnostou, A.1    Lee, E.S.2    Kessimian, N.3    Levinson, R.4    Steiner, M.5
  • 360
    • 0033561341 scopus 로고    scopus 로고
    • Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
    • Ribatti D, Presta M, Vacca A, et al. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood. 1999;93(8):2627-2636.
    • (1999) Blood , vol.93 , Issue.8 , pp. 2627-2636
    • Ribatti, D.1    Presta, M.2    Vacca, A.3
  • 362
    • 0017118613 scopus 로고
    • In vitro development of chicken erythropoietin-sensitive cells
    • Samarut J, Nigon V. In vitro development of chicken erythropoietin-sensitive cells. Exp Cell Res. 1976;100(2):245-248.
    • (1976) Exp Cell Res , vol.100 , Issue.2 , pp. 245-248
    • Samarut, J.1    Nigon, V.2
  • 363
    • 0028137614 scopus 로고
    • Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro
    • Steinlein P, Deiner E, Leutz A, Beug H. Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro. Growth Factors. 1994;10(1):1-16.
    • (1994) Growth Factors , vol.10 , Issue.1 , pp. 1-16
    • Steinlein, P.1    Deiner, E.2    Leutz, A.3    Beug, H.4
  • 364
    • 77952237026 scopus 로고    scopus 로고
    • Tetracycline-dependent expression of the human erythropoietin gene in transgenic chickens
    • Koo BC, Kwon MS, Lee H, et al. Tetracycline-dependent expression of the human erythropoietin gene in transgenic chickens. Transgenic Res. 2010;19(3):437-447.
    • (2010) Transgenic Res , vol.19 , Issue.3 , pp. 437-447
    • Koo, B.C.1    Kwon, M.S.2    Lee, H.3
  • 365
    • 0036333152 scopus 로고    scopus 로고
    • Erythropoietin receptor signalling is required for normal brain development
    • Yu X, Shacka JJ, Eells JB, et al. Erythropoietin receptor signalling is required for normal brain development. Development. 2002; 129(2):505-516.
    • (2002) Development , vol.129 , Issue.2 , pp. 505-516
    • Yu, X.1    Shacka, J.J.2    Eells, J.B.3
  • 366
    • 33645828185 scopus 로고    scopus 로고
    • Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice
    • Satoh K, Kagaya Y, Nakano M, et al. Important role of endogenous erythropoietin system in recruitment of endothelial progenitor cells in hypoxia-induced pulmonary hypertension in mice. Circulation. 2006;113(11):1442-1450.
    • (2006) Circulation , vol.113 , Issue.11 , pp. 1442-1450
    • Satoh, K.1    Kagaya, Y.2    Nakano, M.3
  • 367
    • 33947728801 scopus 로고    scopus 로고
    • Important role of erythropoietin receptor to promote VEGF expression and angiogenesis in peripheral ischemia in mice
    • Nakano M, Satoh K, Fukumoto Y, et al. Important role of erythropoietin receptor to promote VEGF expression and angiogenesis in peripheral ischemia in mice. Circ Res. 2007;100(5):662-669.
    • (2007) Circ Res , vol.100 , Issue.5 , pp. 662-669
    • Nakano, M.1    Satoh, K.2    Fukumoto, Y.3
  • 368
    • 0037447256 scopus 로고    scopus 로고
    • Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling
    • Calvillo L, Latini R, Kajstura J, et al. Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci U S A. 2003;100(8):4802-4806.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.8 , pp. 4802-4806
    • Calvillo, L.1    Latini, R.2    Kajstura, J.3
  • 369
    • 0141593556 scopus 로고    scopus 로고
    • Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats
    • Moon C, Krawczyk M, Ahn D, et al. Erythropoietin reduces myocardial infarction and left ventricular functional decline after coronary artery ligation in rats. Proc Natl Acad Sci U S A. 2003;100(20):11612-11617.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.20 , pp. 11612-11617
    • Moon, C.1    Krawczyk, M.2    Ahn, D.3
  • 370
    • 0041659121 scopus 로고    scopus 로고
    • Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway
    • Tramontano AF, Muniyappa R, Black AD, et al. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun. 2003; 308(4):990-994.
    • (2003) Biochem Biophys Res Commun , vol.308 , Issue.4 , pp. 990-994
    • Tramontano, A.F.1    Muniyappa, R.2    Black, A.D.3
  • 371
    • 34347212063 scopus 로고    scopus 로고
    • Darbepoetin alfa protects the rat heart against infarction: Dose-response, phase of action, and mechanisms
    • Baker JE, Kozik D, Hsu AK, Fu X, Tweddell JS, Gross GJ. Darbepoetin alfa protects the rat heart against infarction: dose-response, phase of action, and mechanisms. J Cardiovasc Pharmacol. 2007;49(6):337-345.
    • (2007) J Cardiovasc Pharmacol , vol.49 , Issue.6 , pp. 337-345
    • Baker, J.E.1    Kozik, D.2    Hsu, A.K.3    Fu, X.4    Tweddell, J.S.5    Gross, G.J.6
  • 372
    • 2442714969 scopus 로고    scopus 로고
    • Cardioprotective effects of erythropoietin in the reperfused ischemic heart: A potential role for cardiac fibroblasts
    • Parsa CJ, Kim J, Riel RU, et al. Cardioprotective effects of erythropoietin in the reperfused ischemic heart: a potential role for cardiac fibroblasts. J Biol Chem. 2004;279(20):20655-20662.
    • (2004) J Biol Chem , vol.279 , Issue.20 , pp. 20655-20662
    • Parsa, C.J.1    Kim, J.2    Riel, R.U.3
  • 373
    • 34247201113 scopus 로고    scopus 로고
    • Protective role of endogenous erythropoietin system in nonhematopoietic cells against pressure overload-induced left ventricular dysfunction in mice
    • Asaumi Y, Kagaya Y, Takeda M, et al. Protective role of endogenous erythropoietin system in nonhematopoietic cells against pressure overload-induced left ventricular dysfunction in mice. Circulation. 2007;115(15):2022-2032.
    • (2007) Circulation , vol.115 , Issue.15 , pp. 2022-2032
    • Asaumi, Y.1    Kagaya, Y.2    Takeda, M.3
  • 374
    • 33746269418 scopus 로고    scopus 로고
    • Endogenous erythropoietin system in non-hematopoietic lineage cells plays a protective role in myocardial ischemia/reperfusion
    • Tada H, Kagaya Y, Takeda M, et al. Endogenous erythropoietin system in non-hematopoietic lineage cells plays a protective role in myocardial ischemia/reperfusion. Cardiovasc Res. 2006;71(3):466-477.
    • (2006) Cardiovasc Res , vol.71 , Issue.3 , pp. 466-477
    • Tada, H.1    Kagaya, Y.2    Takeda, M.3
  • 375
    • 0035957426 scopus 로고    scopus 로고
    • Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
    • Siren AL, Fratelli M, Brines M, et al. Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress. Proc Natl Acad Sci U S A. 2001;98(7):4044-4049.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.7 , pp. 4044-4049
    • Siren, A.L.1    Fratelli, M.2    Brines, M.3
  • 376
    • 0032516086 scopus 로고    scopus 로고
    • In vivo evidence that erythropoietin protects neurons from ischemic damage
    • Sakanaka M, Wen TC, Matsuda S, et al. In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc Natl Acad Sci U S A. 1998;95(8):4635-4640.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.8 , pp. 4635-4640
    • Sakanaka, M.1    Wen, T.C.2    Matsuda, S.3
  • 377
    • 0037047154 scopus 로고    scopus 로고
    • Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma
    • Gorio A, Gokmen N, Erbayraktar S, et al. Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma. Proc Natl Acad Sci U S A. 2002;99(14):9450-9455.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.14 , pp. 9450-9455
    • Gorio, A.1    Gokmen, N.2    Erbayraktar, S.3
  • 378
    • 48249136580 scopus 로고    scopus 로고
    • Antiapoptotic properties of erythropoiesis-stimulating proteins in models of cisplatin-induced acute kidney injury
    • Salahudeen AK, Haider N, Jenkins J, et al. Antiapoptotic properties of erythropoiesis-stimulating proteins in models of cisplatin-induced acute kidney injury. Am J Physiol Renal Physiol. 2008;294(6):F1354-F1365.
    • (2008) Am J Physiol Renal Physiol , vol.294 , Issue.6
    • Salahudeen, A.K.1    Haider, N.2    Jenkins, J.3
  • 380
    • 79953842857 scopus 로고    scopus 로고
    • Erythropoietin: A hormone with multiple functions [review]
    • Lombardero M, Kovacs K, Scheithauer BW. Erythropoietin: a hormone with multiple functions [review]. Pathobiology. 2011;78(1):41-53.
    • (2011) Pathobiology , vol.78 , Issue.1 , pp. 41-53
    • Lombardero, M.1    Kovacs, K.2    Scheithauer, B.W.3
  • 381
    • 40449087690 scopus 로고    scopus 로고
    • The non-haematopoietic biological effects of erythropoietin
    • Arcasoy MO. The non-haematopoietic biological effects of erythropoietin. Br J Haematol. 2008;141(1):14-31.
    • (2008) Br J Haematol , vol.141 , Issue.1 , pp. 14-31
    • Arcasoy, M.O.1
  • 382
    • 34447294258 scopus 로고    scopus 로고
    • Attenuation of inflammation and apoptosis by pre- and posttreatment of darbepoetin-alpha in acute liver failure of mice
    • Minh KL, Klemm K, Abshagen K, Eipel C, Menger MD, Vollmar B. Attenuation of inflammation and apoptosis by pre- and posttreatment of darbepoetin-alpha in acute liver failure of mice. Am J Pathol. 2007;170(6):1954-1963.
    • (2007) Am J Pathol , vol.170 , Issue.6 , pp. 1954-1963
    • Minh, K.L.1    Klemm, K.2    Abshagen, K.3    Eipel, C.4    Menger, M.D.5    Vollmar, B.6
  • 383
    • 33749442773 scopus 로고    scopus 로고
    • Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat
    • Sepodes B, Maio R, Pinto R, et al. Recombinant human erythropoietin protects the liver from hepatic ischemia-reperfusion injury in the rat. Transpl Int. 2006;19(11):919-926.
    • (2006) Transpl Int , vol.19 , Issue.11 , pp. 919-926
    • Sepodes, B.1    Maio, R.2    Pinto, R.3
  • 385
    • 0031037376 scopus 로고    scopus 로고
    • Detection of erythropoietin in human liquor: Intrinsic erythropoietin production in the brain
    • Marti HH, Gassmann M, Wenger RH, et al. Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain. Kidney Int. 1997;51(2):416-418.
    • (1997) Kidney Int , vol.51 , Issue.2 , pp. 416-418
    • Marti, H.H.1    Gassmann, M.2    Wenger, R.H.3
  • 386
    • 8844236181 scopus 로고    scopus 로고
    • Passage of erythropoietic agents across the blood-brain barrier: A comparison of human and murine erythropoietin and the analog darbepoetin alfa
    • Banks WA, Jumbe NL, Farrell CL, Niehoff ML, Heatherington AC. Passage of erythropoietic agents across the blood-brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa. Eur J Pharmacol. 2004;505(1-3):93-101.
    • (2004) Eur J Pharmacol , vol.505 , Issue.1-3 , pp. 93-101
    • Banks, W.A.1    Jumbe, N.L.2    Farrell, C.L.3    Niehoff, M.L.4    Heatherington, A.C.5
  • 387
    • 0030856362 scopus 로고    scopus 로고
    • Erythropoietin is present in the cerebrospinal fluid of neonates
    • Juul SE, Harcum J, Li Y, Christensen RD. Erythropoietin is present in the cerebrospinal fluid of neonates. J Pediatr. 1997;130(3):428-430.
    • (1997) J Pediatr , vol.130 , Issue.3 , pp. 428-430
    • Juul, S.E.1    Harcum, J.2    Li, Y.3    Christensen, R.D.4
  • 388
    • 32544437335 scopus 로고    scopus 로고
    • A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery
    • Tsai PT, Ohab JJ, Kertesz N, et al. A critical role of erythropoietin receptor in neurogenesis and post-stroke recovery. J Neurosci. 2006; 26(4):1269-1274.
    • (2006) J Neurosci , vol.26 , Issue.4 , pp. 1269-1274
    • Tsai, P.T.1    Ohab, J.J.2    Kertesz, N.3
  • 389
    • 35349001269 scopus 로고    scopus 로고
    • Preventive cardioprotection of erythropoietin against doxorubicin-induced cardiomyopathy
    • Chen X, Chen Y, Bi Y, et al. Preventive cardioprotection of erythropoietin against doxorubicin-induced cardiomyopathy. Cardiovasc Drugs Ther. 2007;21(5):367-374.
    • (2007) Cardiovasc Drugs Ther , vol.21 , Issue.5 , pp. 367-374
    • Chen, X.1    Chen, Y.2    Bi, Y.3
  • 390
    • 18144436505 scopus 로고    scopus 로고
    • Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus
    • Juul SE, Yachnis AT, Christensen RD. Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus. Early Hum Dev. 1998;52(3):235-249.
    • (1998) Early Hum Dev , vol.52 , Issue.3 , pp. 235-249
    • Juul, S.E.1    Yachnis, A.T.2    Christensen, R.D.3
  • 391
    • 0033029430 scopus 로고    scopus 로고
    • Human, rat, and mouse kidney cells express functional erythropoietin receptors
    • Westenfelder C, Biddle DL, Baranowski RL. Human, rat, and mouse kidney cells express functional erythropoietin receptors. Kidney Int. 1999;55(3):808-820.
    • (1999) Kidney Int , vol.55 , Issue.3 , pp. 808-820
    • Westenfelder, C.1    Biddle, D.L.2    Baranowski, R.L.3
  • 392
    • 0038163900 scopus 로고    scopus 로고
    • Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
    • Cai Z, Manalo DJ, Wei G, et al. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation. 2003;108(1):79-85.
    • (2003) Circulation , vol.108 , Issue.1 , pp. 79-85
    • Cai, Z.1    Manalo, D.J.2    Wei, G.3
  • 393
    • 6944237300 scopus 로고    scopus 로고
    • Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor
    • Brines M, Grasso G, Fiordaliso F, et al. Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci U S A. 2004;101(41):14907-14912.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.41 , pp. 14907-14912
    • Brines, M.1    Grasso, G.2    Fiordaliso, F.3
  • 394
    • 34249056816 scopus 로고    scopus 로고
    • Are erythropoietin receptors expressed in tumors? Facts and fiction - more careful studies are needed
    • Agarwal N, Gordeuk VR, Prchal JT. Are erythropoietin receptors expressed in tumors? Facts and fiction - more careful studies are needed. J Clin Oncol. 2007;25(13):1813-1814.
    • (2007) J Clin Oncol , vol.25 , Issue.13 , pp. 1813-1814
    • Agarwal, N.1    Gordeuk, V.R.2    Prchal, J.T.3
  • 395
    • 85047691007 scopus 로고    scopus 로고
    • A novel protective effect of erythropoietin in the infarcted heart
    • Parsa CJ, Matsumoto A, Kim J, et al. A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest. 2003;112(7):999-1007.
    • (2003) J Clin Invest , vol.112 , Issue.7 , pp. 999-1007
    • Parsa, C.J.1    Matsumoto, A.2    Kim, J.3
  • 396
    • 0033922341 scopus 로고    scopus 로고
    • Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathway
    • Akimoto T, Kusano E, Inaba T, et al. Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathway. Kidney Int. 2000;58(1):269-282.
    • (2000) Kidney Int , vol.58 , Issue.1 , pp. 269-282
    • Akimoto, T.1    Kusano, E.2    Inaba, T.3
  • 397
    • 13844320400 scopus 로고    scopus 로고
    • A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury
    • Fiordaliso F, Chimenti S, Staszewsky L, et al. A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2005;102(6): 2046-2051.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.6 , pp. 2046-2051
    • Fiordaliso, F.1    Chimenti, S.2    Staszewsky, L.3
  • 398
    • 36248931074 scopus 로고    scopus 로고
    • Erythropoietin enhances the angiogenic potency of autologous bone marrow stromal cells in a rat model of myocardial infarction
    • Zhang D, Zhang F, Zhang Y, et al. Erythropoietin enhances the angiogenic potency of autologous bone marrow stromal cells in a rat model of myocardial infarction. Cardiology. 2007;108(4): 228-236.
    • (2007) Cardiology , vol.108 , Issue.4 , pp. 228-236
    • Zhang, D.1    Zhang, F.2    Zhang, Y.3
  • 399
    • 0036896201 scopus 로고    scopus 로고
    • Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: Evidence from an in vitro model
    • Ruscher K, Freyer D, Karsch M, et al. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci. 2002;22(23):10291-10301.
    • (2002) J Neurosci , vol.22 , Issue.23 , pp. 10291-10301
    • Ruscher, K.1    Freyer, D.2    Karsch, M.3
  • 400
    • 0141595004 scopus 로고    scopus 로고
    • Preconditioning with erythropoietin protects against subsequent ischemia-reperfusion injury in rat kidney
    • Yang CW, Li C, Jung JY, et al. Preconditioning with erythropoietin protects against subsequent ischemia-reperfusion injury in rat kidney. FASEB J. 2003;17(12):1754-1755.
    • (2003) FASEB J , vol.17 , Issue.12 , pp. 1754-1755
    • Yang, C.W.1    Li, C.2    Jung, J.Y.3
  • 402
    • 0035171094 scopus 로고    scopus 로고
    • Recombinant erythropoietin rapidly treats anemia in ischemic acute renal failure
    • Nemoto T, Yokota N, Keane WF, Rabb H. Recombinant erythropoietin rapidly treats anemia in ischemic acute renal failure. Kidney Int. 2001; 59(1):246-251.
    • (2001) Kidney Int , vol.59 , Issue.1 , pp. 246-251
    • Nemoto, T.1    Yokota, N.2    Keane, W.F.3    Rabb, H.4
  • 403
    • 34147199187 scopus 로고    scopus 로고
    • Recombinant human erythropoietin suppresses symptom onset and progression of G93A-SOD1 mouse model of ALS by preventing motor neuron death and inflammation
    • Koh SH, Kim Y, Kim HY, Cho GW, Kim KS, Kim SH. Recombinant human erythropoietin suppresses symptom onset and progression of G93A-SOD1 mouse model of ALS by preventing motor neuron death and inflammation. Eur J Neurosci. 2007;25(7):1923-1930.
    • (2007) Eur J Neurosci , vol.25 , Issue.7 , pp. 1923-1930
    • Koh, S.H.1    Kim, Y.2    Kim, H.Y.3    Cho, G.W.4    Kim, K.S.5    Kim, S.H.6
  • 404
    • 33847687265 scopus 로고    scopus 로고
    • Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model
    • Grunfeld JF, Barhum Y, Blondheim N, Rabey JM, Melamed E, Offen D. Erythropoietin delays disease onset in an amyotrophic lateral sclerosis model. Exp Neurol. 2007;204(1):260-263.
    • (2007) Exp Neurol , vol.204 , Issue.1 , pp. 260-263
    • Grunfeld, J.F.1    Barhum, Y.2    Blondheim, N.3    Rabey, J.M.4    Melamed, E.5    Offen, D.6
  • 406
    • 0037064261 scopus 로고    scopus 로고
    • Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis
    • Agnello D, Bigini P, Villa P, et al. Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res. 2002;952(1):128-134.
    • (2002) Brain Res , vol.952 , Issue.1 , pp. 128-134
    • Agnello, D.1    Bigini, P.2    Villa, P.3
  • 407
    • 58849144706 scopus 로고    scopus 로고
    • Darbepoetin alpha, a long-acting erythropoeitin derivate, does not alter LPS evoked myocardial depression and gene expression of Bax, Bcl-Xs, Bcl-XL, Bcl-2, and TNF-alpha
    • Brendt P, Frey U, Adamzik M, Schafer ST, Peters J. Darbepoetin alpha, a long-acting erythropoeitin derivate, does not alter LPS evoked myocardial depression and gene expression of Bax, Bcl-Xs, Bcl-XL, Bcl-2, and TNF-alpha. Shock. 2009;31(1):50-54.
    • (2009) Shock , vol.31 , Issue.1 , pp. 50-54
    • Brendt, P.1    Frey, U.2    Adamzik, M.3    Schafer, S.T.4    Peters, J.5
  • 408
    • 36349005311 scopus 로고    scopus 로고
    • No neuroprotective effect of erythropoietin under clinical treatment conditions in a rabbit model of Escherichia coli meningitis
    • Spreer A, Gerber J, Hanssen M, Nau R. No neuroprotective effect of erythropoietin under clinical treatment conditions in a rabbit model of Escherichia coli meningitis. Pediatr Res. 2007;62(6):680-683.
    • (2007) Pediatr Res , vol.62 , Issue.6 , pp. 680-683
    • Spreer, A.1    Gerber, J.2    Hanssen, M.3    Nau, R.4
  • 409
    • 84855939143 scopus 로고    scopus 로고
    • Organ-protective and immunomodulatory effects of erythropoietin - an update on recent clinical trials
    • Sølling C. Organ-protective and immunomodulatory effects of erythropoietin - an update on recent clinical trials. Basic Clin Pharmacol Toxicol. 2012;110(2):113-121.
    • (2012) Basic Clin Pharmacol Toxicol , vol.110 , Issue.2 , pp. 113-121
    • Sølling, C.1
  • 410
    • 70949095435 scopus 로고    scopus 로고
    • Recombinant human erythropoietin in the treatment of acute ischemic stroke
    • Ehrenreich H, Weissenborn K, Prange H, et al. Recombinant human erythropoietin in the treatment of acute ischemic stroke. Stroke. 2009;40(12):e647-e656.
    • (2009) Stroke , vol.40 , Issue.12
    • Ehrenreich, H.1    Weissenborn, K.2    Prange, H.3
  • 411
    • 36248977612 scopus 로고    scopus 로고
    • Erythropoietin in patients with aneurysmal subarachnoid haemorrhage: A double blind randomised clinical trial
    • Springborg JB, Moller C, Gideon P, Jorgensen OS, Juhler M, Olsen NV. Erythropoietin in patients with aneurysmal subarachnoid haemorrhage: a double blind randomised clinical trial. Acta Neurochir (Wien). 2007;149(11):1089-1100.
    • (2007) Acta Neurochir (Wien) , vol.149 , Issue.11 , pp. 1089-1100
    • Springborg, J.B.1    Moller, C.2    Gideon, P.3    Jorgensen, O.S.4    Juhler, M.5    Olsen, N.V.6
  • 412
    • 74049110427 scopus 로고    scopus 로고
    • Erythropoiesis stimulating agent administration improves survival after severe traumatic brain injury: A matched case control study
    • Talving P, Lustenberger T, Kobayashi L, et al. Erythropoiesis stimulating agent administration improves survival after severe traumatic brain injury: a matched case control study. Ann Surg. 2010; 251(1):1-4.
    • (2010) Ann Surg , vol.251 , Issue.1 , pp. 1-4
    • Talving, P.1    Lustenberger, T.2    Kobayashi, L.3
  • 413
    • 70349492321 scopus 로고    scopus 로고
    • Erythropoietin to augment myocardial salvage induced by coronary thrombolysis in patients with ST segment elevation acute myocardial infarction
    • Binbrek AS, Rao NS, Al KN, Assaqqaf J, Sobel BE. Erythropoietin to augment myocardial salvage induced by coronary thrombolysis in patients with ST segment elevation acute myocardial infarction. Am J Cardiol. 2009;(8):1035-1040.
    • (2009) Am J Cardiol , Issue.8 , pp. 1035-1040
    • Binbrek, A.S.1    Rao, N.S.2    Al, K.N.3    Assaqqaf, J.4    Sobel, B.E.5
  • 414
    • 67749098636 scopus 로고    scopus 로고
    • Clinical trials update from the American College of Cardiology 2009: ADMIRE-HF, PRIMA, STICH, REVERSE, IRIS, partial ventricular support, FIX-HF-5, vagal stimulation, REVIVAL-3, pre-RELAX-AHF, ACTIVE-A, HF-ACTION, JUPITER, AURORA, and OMEGA
    • Cleland JG, Coletta AP, Clark AL, Cullington D. Clinical trials update from the American College of Cardiology 2009: ADMIRE-HF, PRIMA, STICH, REVERSE, IRIS, partial ventricular support, FIX-HF-5, vagal stimulation, REVIVAL-3, pre-RELAX-AHF, ACTIVE-A, HF-ACTION, JUPITER, AURORA, and OMEGA. Eur J Heart Fail. 2009;11(6):622-630.
    • (2009) Eur J Heart Fail , vol.11 , Issue.6 , pp. 622-630
    • Cleland, J.G.1    Coletta, A.P.2    Clark, A.L.3    Cullington, D.4
  • 415
    • 79951722690 scopus 로고    scopus 로고
    • High-dose erythropoietin in patients with acute myocardial infarction: A pilot, randomised, placebo-controlled study
    • Ferrario M, Arbustini E, Massa M, et al. High-dose erythropoietin in patients with acute myocardial infarction: a pilot, randomised, placebo-controlled study. Int J Cardiol. 2011;147(1):124-131.
    • (2011) Int J Cardiol , vol.147 , Issue.1 , pp. 124-131
    • Ferrario, M.1    Arbustini, E.2    Massa, M.3
  • 416
    • 79955877895 scopus 로고    scopus 로고
    • Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: A randomized controlled trial
    • Najjar SS, Rao SV, Melloni C, et al. Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial. JAMA. 2011;305(18):1863-1872.
    • (2011) JAMA , vol.305 , Issue.18 , pp. 1863-1872
    • Najjar, S.S.1    Rao, S.V.2    Melloni, C.3
  • 417
    • 78349287458 scopus 로고    scopus 로고
    • Erythropoietin in patients with acute st-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention a randomized, double-blind trial
    • Ott I, Schulz S, Mehilli J, et al. Erythropoietin in patients with acute st-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention a randomized, double-blind trial. Circ Cardiovasc Interv. 2010;3(5):408-413.
    • (2010) Circ Cardiovasc Interv , vol.3 , Issue.5 , pp. 408-413
    • Ott, I.1    Schulz, S.2    Mehilli, J.3
  • 418
    • 84866773953 scopus 로고    scopus 로고
    • A randomized placebo controlled trial of intravenous erythropoietin to reduce infarct size after st-segment elevation myocardial infarction: Primary results of the REVEAL trial
    • Rao SV, Kilaru R, Povsic TJ, et al. A randomized placebo controlled trial of intravenous erythropoietin to reduce infarct size after st-segment elevation myocardial infarction: primary results of the REVEAL trial. Circulation. 2010;122(21):2222.
    • (2222) Circulation , vol.122 , Issue.21 , pp. 2010
    • Rao, S.V.1    Kilaru, R.2    Povsic, T.J.3
  • 419
    • 77958518157 scopus 로고    scopus 로고
    • A single dose of erythropoietin in ST-elevation myocardial infarction
    • Voors AA, Belonje AM, Zijlstra F, et al. A single dose of erythropoietin in ST-elevation myocardial infarction. Eur Heart J. 2010;31(21): 2593-2600.
    • (2010) Eur Heart J , vol.31 , Issue.21 , pp. 2593-2600
    • Voors, A.A.1    Belonje, A.M.2    Zijlstra, F.3
  • 420
    • 0036714898 scopus 로고    scopus 로고
    • Erythropoietin therapy may retard progression in chronic renal transplant dysfunction
    • Becker BN, Becker YT, Leverson GE, Heisey DM. Erythropoietin therapy may retard progression in chronic renal transplant dysfunction. Nephrol Dial Transplant. 2002;17(9):1667-1673.
    • (2002) Nephrol Dial Transplant , vol.17 , Issue.9 , pp. 1667-1673
    • Becker, B.N.1    Becker, Y.T.2    Leverson, G.E.3    Heisey, D.M.4
  • 421
    • 84856708505 scopus 로고    scopus 로고
    • High-dose erythropoietin has no effect on short-or long-term graft function following deceased donor kidney transplantation
    • Hafer C, Becker T, Kielstein JT, et al. High-dose erythropoietin has no effect on short-or long-term graft function following deceased donor kidney transplantation. Kidney Int. 2012;81(3):314-320.
    • (2012) Kidney Int , vol.81 , Issue.3 , pp. 314-320
    • Hafer, C.1    Becker, T.2    Kielstein, J.T.3
  • 422
    • 75149185907 scopus 로고    scopus 로고
    • Impact of very early high doses of recombinant erythropoietin on anemia and allograft function in de novo kidney-transplant patients
    • Kamar N, Reboux A-H, Cointault O, et al. Impact of very early high doses of recombinant erythropoietin on anemia and allograft function in de novo kidney-transplant patients. Transpl Int. 2010;23(3):277-284.
    • (2010) Transpl Int , vol.23 , Issue.3 , pp. 277-284
    • Kamar, N.1    Reboux, A.-H.2    Cointault, O.3
  • 423
    • 77954078811 scopus 로고    scopus 로고
    • High dose epoetin beta in the first weeks following renal transplantation and delayed graft function: Results of the Neo-PDGF study [brief communication]
    • Martinez F, Kamar N, Pallet N, et al. High dose epoetin beta in the first weeks following renal transplantation and delayed graft function: results of the Neo-PDGF study [brief communication]. Am J Transplant. 2010;10(7):1704-1709.
    • (2010) Am J Transplant , vol.10 , Issue.7 , pp. 1704-1709
    • Martinez, F.1    Kamar, N.2    Pallet, N.3
  • 424
    • 77955915903 scopus 로고    scopus 로고
    • Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial)
    • Endre ZH, Walker RJ, Pickering JW, et al. Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial). Kidney Int. 2010;77(11):1020-1030.
    • (2010) Kidney Int , vol.77 , Issue.11 , pp. 1020-1030
    • Endre, Z.H.1    Walker, R.J.2    Pickering, J.W.3
  • 425
    • 27144517603 scopus 로고    scopus 로고
    • Use of EPO in critically ill patients with acute renal failure requiring renal replacement therapy
    • Park J, Gage BF, Vijayan A. Use of EPO in critically ill patients with acute renal failure requiring renal replacement therapy. American Journal of Kidney Diseases 2005;46(5):791-798.
    • (2005) American Journal of Kidney Diseases , vol.46 , Issue.5 , pp. 791-798
    • Park, J.1    Gage, B.F.2    Vijayan, A.3
  • 426
    • 66149129192 scopus 로고    scopus 로고
    • Prevention of acute kidney injury by erythropoietin in patients undergoing coronary artery bypass grafting: A pilot study
    • Song YR, Lee T, You SJ, et al. Prevention of acute kidney injury by erythropoietin in patients undergoing coronary artery bypass grafting: a pilot study. Am J Nephrol. 2009;30(3):253-260.
    • (2009) Am J Nephrol , vol.30 , Issue.3 , pp. 253-260
    • Song, Y.R.1    Lee, T.2    You, S.J.3
  • 427
    • 84857469947 scopus 로고    scopus 로고
    • Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: Acute and prolonged studies in healthy human subjects
    • Christensen B, Lundby C, Jessen N, et al. Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects. PloS One 2012;7(2):e31857.
    • (2012) PloS One , vol.7 , Issue.2
    • Christensen, B.1    Lundby, C.2    Jessen, N.3
  • 428
    • 3042725549 scopus 로고    scopus 로고
    • Derivatives of erythropoietin that are tissue protective but not erythropoietic
    • Leist M, Ghezzi P, Grasso G, et al. Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science. 2004; 305(5681):239-242.
    • (2004) Science , vol.305 , Issue.5681 , pp. 239-242
    • Leist, M.1    Ghezzi, P.2    Grasso, G.3
  • 429
    • 33644775862 scopus 로고    scopus 로고
    • Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties
    • Moon C, Krawczyk M, Paik D, et al. Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties. J Pharmacol Exp Ther. 2006;316(3):999-1005.
    • (2006) J Pharmacol Exp Ther , vol.316 , Issue.3 , pp. 999-1005
    • Moon, C.1    Krawczyk, M.2    Paik, D.3
  • 430
    • 33845979434 scopus 로고    scopus 로고
    • Carbamylated erythropoietin protects the kidneys from ischemia-reperfusion injury without stimulating erythropoiesis
    • Imamura R, Isaka Y, Ichimaru N, Takahara S, Okuyama A. Carbamylated erythropoietin protects the kidneys from ischemia-reperfusion injury without stimulating erythropoiesis. Biochem Biophys Res Commun. 2007;353(3):786-792.
    • (2007) Biochem Biophys Res Commun , vol.353 , Issue.3 , pp. 786-792
    • Imamura, R.1    Isaka, Y.2    Ichimaru, N.3    Takahara, S.4    Okuyama, A.5
  • 431
    • 42249101919 scopus 로고    scopus 로고
    • Carbamylated erythropoietin improves angiogenesis and protects the kidneys from ischemia-reperfusion injury
    • Imamura R, Okumi M, Isaka Y, et al. Carbamylated erythropoietin improves angiogenesis and protects the kidneys from ischemia-reperfusion injury. Cell Transplant. 2008;17(1-2):135-141.
    • (2008) Cell Transplant , vol.17 , Issue.1-2 , pp. 135-141
    • Imamura, R.1    Okumi, M.2    Isaka, Y.3
  • 432
    • 44449166538 scopus 로고    scopus 로고
    • Nonerythropoietic derivative of erythropoietin protects against tubulointerstitial injury in a unilateral ureteral obstruction model
    • Kitamura H, Isaka Y, Takabatake Y, et al. Nonerythropoietic derivative of erythropoietin protects against tubulointerstitial injury in a unilateral ureteral obstruction model. Nephrol Dial Transplant. 2008;23(5):1521-1528.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.5 , pp. 1521-1528
    • Kitamura, H.1    Isaka, Y.2    Takabatake, Y.3
  • 433
    • 34447118238 scopus 로고    scopus 로고
    • Erythropoietin and carbamylated erythropoietin are neuroprotective following spinal cord hemisection in the rat
    • King VR, Averill SA, Hewazy D, Priestley JV, Torup L, Michael-Titus AT. Erythropoietin and carbamylated erythropoietin are neuroprotective following spinal cord hemisection in the rat. Eur J Neurosci. 2007;26(1):90-100.
    • (2007) Eur J Neurosci , vol.26 , Issue.1 , pp. 90-100
    • King, V.R.1    Averill, S.A.2    Hewazy, D.3    Priestley, J.V.4    Torup, L.5    Michael-Titus, A.T.6
  • 434
    • 33847300431 scopus 로고    scopus 로고
    • Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures
    • Montero M, Poulsen FR, Noraberg J, et al. Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures. Exp Neurol. 2007;204(1):106-117.
    • (2007) Exp Neurol , vol.204 , Issue.1 , pp. 106-117
    • Montero, M.1    Poulsen, F.R.2    Noraberg, J.3
  • 435
    • 37549024253 scopus 로고    scopus 로고
    • Erythropoietin and its carbamylated derivative prevent the development of experimental diabetic autonomic neuropathy in STZ-induced diabetic NOD-SCID mice
    • Schmidt RE, Green KG, Feng D, et al. Erythropoietin and its carbamylated derivative prevent the development of experimental diabetic autonomic neuropathy in STZ-induced diabetic NOD-SCID mice. Exp Neurol. 2008;209(1):161-170.
    • (2008) Exp Neurol , vol.209 , Issue.1 , pp. 161-170
    • Schmidt, R.E.1    Green, K.G.2    Feng, D.3
  • 436
    • 0028824907 scopus 로고
    • Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5
    • Robb L, Drinkwater CC, Metcalf D, et al. Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5. Proc Natl Acad Sci U S A. 1995;92(21): 9565-9569.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.21 , pp. 9565-9569
    • Robb, L.1    Drinkwater, C.C.2    Metcalf, D.3
  • 437
    • 0029881372 scopus 로고    scopus 로고
    • Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor beta-chain: Implications for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells
    • Nicola NA, Robb L, Metcalf D, Cary D, Drinkwater CC, Begley CG. Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor beta-chain: implications for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells. Blood. 1996;87(7):2665-2674.
    • (1996) Blood , vol.87 , Issue.7 , pp. 2665-2674
    • Nicola, N.A.1    Robb, L.2    Metcalf, D.3    Cary, D.4    Drinkwater, C.C.5    Begley, C.G.6
  • 438
    • 0032400840 scopus 로고    scopus 로고
    • Functional analysis of mature hematopoietic cells from mice lacking the betac chain of the granulocyte-macrophage colony-stimulating factor receptor
    • Scott CL, Hughes DA, Cary D, Nicola NA, Begley CG, Robb L. Functional analysis of mature hematopoietic cells from mice lacking the betac chain of the granulocyte-macrophage colony-stimulating factor receptor. Blood. 1998;92(11):4119-4127.
    • (1998) Blood , vol.92 , Issue.11 , pp. 4119-4127
    • Scott, C.L.1    Hughes, D.A.2    Cary, D.3    Nicola, N.A.4    Begley, C.G.5    Robb, L.6
  • 439
    • 0034663295 scopus 로고    scopus 로고
    • Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3-specific receptor beta-chain-null cells: No evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor
    • Scott CL, Robb L, Papaevangeliou B, Mansfield R, Nicola NA, Begley CG. Reassessment of interactions between hematopoietic receptors using common beta-chain and interleukin-3-specific receptor beta-chain-null cells: no evidence of functional interactions with receptors for erythropoietin, granulocyte colony-stimulating factor, or stem cell factor. Blood. 2000;96(4):1588-1590.
    • (2000) Blood , vol.96 , Issue.4 , pp. 1588-1590
    • Scott, C.L.1    Robb, L.2    Papaevangeliou, B.3    Mansfield, R.4    Nicola, N.A.5    Begley, C.G.6
  • 440
    • 0035942272 scopus 로고    scopus 로고
    • Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models
    • Mittelman M, Neumann D, Peled A, Kanter P, Haran-Ghera N. Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models. Proc Natl Acad Sci U S A. 2001;98(9):5181-5186.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.9 , pp. 5181-5186
    • Mittelman, M.1    Neumann, D.2    Peled, A.3    Kanter, P.4    Haran-Ghera, N.5
  • 441
    • 0142124313 scopus 로고    scopus 로고
    • The implications of anemia in multiple myeloma
    • Mittelman M. The implications of anemia in multiple myeloma. Clin Lymphoma. 2003;4 Suppl 1:S23-S29.
    • (2003) Clin Lymphoma , Issue.4 SUPPL 1
    • Mittelman, M.1
  • 442
    • 0041322520 scopus 로고    scopus 로고
    • Impact of anemia prevention by recombinant human erythropoietin on the sensitivity of xenografted glioblastomas to fractionated irradiation
    • Stuben G, Thews O, Pottgen C, et al. Impact of anemia prevention by recombinant human erythropoietin on the sensitivity of xenografted glioblastomas to fractionated irradiation. Strahlenther Onkol. 2003; 179(9):620-625.
    • (2003) Strahlenther Onkol , vol.179 , Issue.9 , pp. 620-625
    • Stuben, G.1    Thews, O.2    Pottgen, C.3
  • 443
    • 4444318802 scopus 로고    scopus 로고
    • Erythropoietin modulates the anticancer activity of chemotherapeutic drugs in a murine lung cancer model
    • Sigounas G, Sallah S, Sigounas VY. Erythropoietin modulates the anticancer activity of chemotherapeutic drugs in a murine lung cancer model. Cancer Lett. 2004;214(2):171-179.
    • (2004) Cancer Lett , vol.214 , Issue.2 , pp. 171-179
    • Sigounas, G.1    Sallah, S.2    Sigounas, V.Y.3
  • 444
    • 0031658227 scopus 로고    scopus 로고
    • Enhanced radiosensitivity in experimental tumours following erythropoietin treatment of chemotherapy-induced anaemia
    • Thews O, Koenig R, Kelleher DK, Kutzner J, Vaupel P. Enhanced radiosensitivity in experimental tumours following erythropoietin treatment of chemotherapy-induced anaemia. Br J Cancer. 1998; 78(6):752-756.
    • (1998) Br J Cancer , vol.78 , Issue.6 , pp. 752-756
    • Thews, O.1    Koenig, R.2    Kelleher, D.K.3    Kutzner, J.4    Vaupel, P.5
  • 445
    • 0032961222 scopus 로고    scopus 로고
    • Effects of recombinant human erythropoietin on the antitumor effect of cisplatin in SCID mice bearing human ovarian cancer: A possible oxygen effect
    • Silver DF, Piver MS. Effects of recombinant human erythropoietin on the antitumor effect of cisplatin in SCID mice bearing human ovarian cancer: a possible oxygen effect. Gynecol Oncol. 1999;73(2):280-284.
    • (1999) Gynecol Oncol , vol.73 , Issue.2 , pp. 280-284
    • Silver, D.F.1    Piver, M.S.2
  • 446
    • 0035017208 scopus 로고    scopus 로고
    • Recombinant human erythropoietin increases the radiosensitivity of xenografted human tumours in anaemic nude mice
    • Stuben G, Thews O, Pottgen C, Knuhmann K, Vaupel P, Stuschke M. Recombinant human erythropoietin increases the radiosensitivity of xenografted human tumours in anaemic nude mice. J Cancer Res Clin Oncol. 2001;127(6):346-350.
    • (2001) J Cancer Res Clin Oncol , vol.127 , Issue.6 , pp. 346-350
    • Stuben, G.1    Thews, O.2    Pottgen, C.3    Knuhmann, K.4    Vaupel, P.5    Stuschke, M.6
  • 447
    • 0035866333 scopus 로고    scopus 로고
    • Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors
    • Thews O, Kelleher DK, Vaupel P. Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors. Cancer Res. 2001;61(4):1358-1361.
    • (2001) Cancer Res , vol.61 , Issue.4 , pp. 1358-1361
    • Thews, O.1    Kelleher, D.K.2    Vaupel, P.3
  • 448
    • 0036091318 scopus 로고    scopus 로고
    • Erythropoietin restores the antitumor effectiveness of photodynamic therapy in mice with chemotherapy-induced anemia
    • Golab J, Olszewska D, Mroz P, et al. Erythropoietin restores the antitumor effectiveness of photodynamic therapy in mice with chemotherapy-induced anemia. Clin Cancer Res. 2002;8(5):1265-1270.
    • (2002) Clin Cancer Res , vol.8 , Issue.5 , pp. 1265-1270
    • Golab, J.1    Olszewska, D.2    Mroz, P.3
  • 449
    • 23844507094 scopus 로고    scopus 로고
    • Recombinant human erythropoietin alpha targets intratumoral blood vessels, improving chemotherapy in human xenograft models
    • Tovari J, Gilly R, Raso E, et al. Recombinant human erythropoietin alpha targets intratumoral blood vessels, improving chemotherapy in human xenograft models. Cancer Res. 2005;65(16):7186-7193.
    • (2005) Cancer Res , vol.65 , Issue.16 , pp. 7186-7193
    • Tovari, J.1    Gilly, R.2    Raso, E.3
  • 450
    • 38149063793 scopus 로고    scopus 로고
    • Recombinant human erythropoietin alpha improves the efficacy of radiotherapy of a human tumor xenograft, affecting tumor cells and microvessels
    • Lovey J, Bereczky B, Gilly R, et al. Recombinant human erythropoietin alpha improves the efficacy of radiotherapy of a human tumor xenograft, affecting tumor cells and microvessels. Strahlenther Onkol. 2008;184(1):1-7.
    • (2008) Strahlenther Onkol , vol.184 , Issue.1 , pp. 1-7
    • Lovey, J.1    Bereczky, B.2    Gilly, R.3
  • 451
    • 0032100515 scopus 로고    scopus 로고
    • Erythropoietin prevents the development of interleukin-12-induced anemia and thrombocytopenia but does not decrease its antitumor activity in mice
    • Golab J, Zagozdzon R, Stoklosa T, Jakobisiak M, Pojda Z, Machaj E. Erythropoietin prevents the development of interleukin-12-induced anemia and thrombocytopenia but does not decrease its antitumor activity in mice. Blood. 1998;91(11):4387-4388.
    • (1998) Blood , vol.91 , Issue.11 , pp. 4387-4388
    • Golab, J.1    Zagozdzon, R.2    Stoklosa, T.3    Jakobisiak, M.4    Pojda, Z.5    Machaj, E.6
  • 452
    • 0141988695 scopus 로고    scopus 로고
    • Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin
    • Blackwell KL, Kirkpatrick JP, Snyder SA, et al. Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin. Cancer Res. 2003;63(19):6162-6165.
    • (2003) Cancer Res , vol.63 , Issue.19 , pp. 6162-6165
    • Blackwell, K.L.1    Kirkpatrick, J.P.2    Snyder, S.A.3
  • 453
    • 33947703740 scopus 로고    scopus 로고
    • Cisplatin-induced peripheral neuropathy: Neuroprotection by erythropoietin without affecting tumour growth
    • Bianchi R, Gilardini A, Rodriguez-Menendez V, et al. Cisplatin-induced peripheral neuropathy: neuroprotection by erythropoietin without affecting tumour growth. Eur J Cancer. 2007;43(4): 710-717.
    • (2007) Eur J Cancer , vol.43 , Issue.4 , pp. 710-717
    • Bianchi, R.1    Gilardini, A.2    Rodriguez-Menendez, V.3
  • 454
    • 0029795885 scopus 로고    scopus 로고
    • Blood flow, oxygenation, and bioenergetic status of tumors after erythropoietin treatment in normal and anemic rats
    • Kelleher DK, Mattheinsen U, Thews O, Vaupel P. Blood flow, oxygenation, and bioenergetic status of tumors after erythropoietin treatment in normal and anemic rats. Cancer Res. 1996;56(20): 4728-4734.
    • (1996) Cancer Res , vol.56 , Issue.20 , pp. 4728-4734
    • Kelleher, D.K.1    Mattheinsen, U.2    Thews, O.3    Vaupel, P.4
  • 455
    • 31444438853 scopus 로고    scopus 로고
    • The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma
    • Kirkpatrick JP, Hardee ME, Snyder SA, et al. The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma. Radiat Res. 2006;165(2):192-201.
    • (2006) Radiat Res , vol.165 , Issue.2 , pp. 192-201
    • Kirkpatrick, J.P.1    Hardee, M.E.2    Snyder, S.A.3
  • 456
    • 2142805906 scopus 로고    scopus 로고
    • Recombinant human erythropoietin attenuates weight loss in a murine cancer cachexia model
    • van Halteren HK, Bongaerts GP, Verhagen CA, et al. Recombinant human erythropoietin attenuates weight loss in a murine cancer cachexia model. J Cancer Res Clin Oncol. 2004;130(4):211-216.
    • (2004) J Cancer Res Clin Oncol , vol.130 , Issue.4 , pp. 211-216
    • van Halteren, H.K.1    Bongaerts, G.P.2    Verhagen, C.A.3
  • 457
    • 33644973850 scopus 로고    scopus 로고
    • Erythropoietin inhibits apoptosis in breast cancer cells via an Akt-dependent pathway without modulating in vivo chemosensitivity
    • Hardee ME, Rabbani ZN, Arcasoy MO, et al. Erythropoietin inhibits apoptosis in breast cancer cells via an Akt-dependent pathway without modulating in vivo chemosensitivity. Mol Cancer Ther. 2006;5(2): 356-361.
    • (2006) Mol Cancer Ther , vol.5 , Issue.2 , pp. 356-361
    • Hardee, M.E.1    Rabbani, Z.N.2    Arcasoy, M.O.3
  • 458
    • 33646508552 scopus 로고    scopus 로고
    • Recombinant erythropoietin beta enhances growth of xenografted human squamous cell carcinoma of the head and neck after surgical trauma
    • Kjellen E, Sasaki Y, Kjellstrom J, Zackrisson B, Wennerberg J. Recombinant erythropoietin beta enhances growth of xenografted human squamous cell carcinoma of the head and neck after surgical trauma. Acta Otolaryngol. 2006;126(5):545-547.
    • (2006) Acta Otolaryngol , vol.126 , Issue.5 , pp. 545-547
    • Kjellen, E.1    Sasaki, Y.2    Kjellstrom, J.3    Zackrisson, B.4    Wennerberg, J.5
  • 459
    • 50949087648 scopus 로고    scopus 로고
    • Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis
    • Okazaki T, Ebihara S, Asada M, Yamanda S, Niu K, Arai H. Erythropoietin promotes the growth of tumors lacking its receptor and decreases survival of tumor-bearing mice by enhancing angiogenesis. Neoplasia. 2008;10(9):932-939.
    • (2008) Neoplasia , vol.10 , Issue.9 , pp. 932-939
    • Okazaki, T.1    Ebihara, S.2    Asada, M.3    Yamanda, S.4    Niu, K.5    Arai, H.6
  • 460
    • 77954089924 scopus 로고    scopus 로고
    • Darbepoetin-alpha enhances hepatectomy-associated stimulation of colorectal liver metastatic growth
    • Rupertus K, Sperling J, Corsten M, et al. Darbepoetin-alpha enhances hepatectomy-associated stimulation of colorectal liver metastatic growth. Ann Surg. 2010;252(1):131-141.
    • (2010) Ann Surg , vol.252 , Issue.1 , pp. 131-141
    • Rupertus, K.1    Sperling, J.2    Corsten, M.3
  • 461
    • 44949252344 scopus 로고    scopus 로고
    • Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: Implication for erythroid differentiation studies
    • Mirabelli P, Di NR, Lo PC, et al. Extended flow cytometry characterization of normal bone marrow progenitor cells by simultaneous detection of aldehyde dehydrogenase and early hematopoietic antigens: implication for erythroid differentiation studies. BMC Physiol. 2008;8:13.
    • (2008) BMC Physiol , vol.8 , pp. 13
    • Mirabelli, P.1    Di, N.R.2    Lo, P.C.3
  • 462
    • 0027321052 scopus 로고
    • Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7
    • Komatsu N, Yamamoto M, Fujita H, et al. Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. Blood. 1993;82(2):456-464.
    • (1993) Blood , vol.82 , Issue.2 , pp. 456-464
    • Komatsu, N.1    Yamamoto, M.2    Fujita, H.3


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