-
1
-
-
0035328802
-
Erythropoietin and erythropoietin receptor expression in human cancer
-
Acs G, Acs P, Beckwith SM, et al. Erythropoietin and erythropoietin receptor expression in human cancer. Cancer Res 2001;61:3561-5.
-
(2001)
Cancer Res
, vol.61
, pp. 3561-3565
-
-
Acs, G.1
Acs, P.2
Beckwith, S.M.3
-
2
-
-
0038751965
-
Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression
-
Acs G, Zhang PJ, McGrath CM, et al. Hypoxia-inducible erythropoietin signaling in squamous dysplasia and squamous cell carcinoma of the uterine cervix and its potential role in cervical carcinogenesis and tumor progression. Am J Pathol 2003;162:1789-806.
-
(2003)
Am J Pathol
, vol.162
, pp. 1789-1806
-
-
Acs, G.1
Zhang, P.J.2
McGrath, C.M.3
-
3
-
-
0025297296
-
Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells
-
Anagnostou A, Lee ES, Kessimian N, et al. Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells. Proc Natl Acad Sci USA 1990;87:5978-82.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 5978-5982
-
-
Anagnostou, A.1
Lee, E.S.2
Kessimian, N.3
-
4
-
-
0037767746
-
Expression of erythropoietin receptor splice variants in human cancer
-
Arcasoy MO, Jiang X, Haroon ZA. Expression of erythropoietin receptor splice variants in human cancer. Biochem Biophys Res Commun 2003;307:999-1007.
-
(2003)
Biochem Biophys Res Commun
, vol.307
, pp. 999-1007
-
-
Arcasoy, M.O.1
Jiang, X.2
Haroon, Z.A.3
-
5
-
-
0142043003
-
Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival
-
Batra S, Perelman N, Luck LR, et al. Pediatric tumor cells express erythropoietin and a functional erythropoietin receptor that promotes angiogenesis and tumor cell survival. Lab Invest 2003;83:1477-87.
-
(2003)
Lab Invest
, vol.83
, pp. 1477-1487
-
-
Batra, S.1
Perelman, N.2
Luck, L.R.3
-
6
-
-
38149090277
-
-
Blohmer JU, Wurschmidt U, Petry G. 6th interim analysis of a prospective, randomized, open and controlled AGO- and NOGGO-Intergroup study: sequential adjuvant chemo-radiotherapy with vs. without epoetin alfa for patients with high risk cervical cancer. Proc Am Soc Clin Oncol 2003;22:447.
-
Blohmer JU, Wurschmidt U, Petry G. 6th interim analysis of a prospective, randomized, open and controlled AGO- and NOGGO-Intergroup study: sequential adjuvant chemo-radiotherapy with vs. without epoetin alfa for patients with high risk cervical cancer. Proc Am Soc Clin Oncol 2003;22:447.
-
-
-
-
7
-
-
33646905411
-
Recombinant human erythropoietins and cancer patients: Updated meta-analysis of 57 studies including 9353 patients
-
Bohlius J, Wilson J, Seidenfeld J, et al. Recombinant human erythropoietins and cancer patients: updated meta-analysis of 57 studies including 9353 patients. J Natl Cancer Sci 2006;98:708-14.
-
(2006)
J Natl Cancer Sci
, vol.98
, pp. 708-714
-
-
Bohlius, J.1
Wilson, J.2
Seidenfeld, J.3
-
8
-
-
38149058247
-
-
FDA Alert. Information for healthcare professionals: erythropoiesis stimulating agents (ESA) [Aranesp (darbepoetin), Epogen (epoetin alfa), and Procrit (epoetin alfa)]. Rockville: Food and Drug Administration, March 9, 2007 (http://www.fda.gov/cder/drug/InfoSheets/HCP/RHE2007HCP.htm, accessed May 25, 2007).
-
FDA Alert. Information for healthcare professionals: erythropoiesis stimulating agents (ESA) [Aranesp (darbepoetin), Epogen (epoetin alfa), and Procrit (epoetin alfa)]. Rockville: Food and Drug Administration, March 9, 2007 (http://www.fda.gov/cder/drug/InfoSheets/HCP/RHE2007HCP.htm, accessed May 25, 2007).
-
-
-
-
9
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia inducible factor 1
-
Forsythe JA, Jiang BH, Iyer NV, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia inducible factor 1. Mol Cell Biol 1996;16:4604-13.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
-
10
-
-
0038626211
-
Tumor response to radiotherapy regulated by endothelial cell apoptosis
-
Garcia-Baross M, Paris F, Cordon-Cardo C, et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis. Science 2003;300:1155-9.
-
(2003)
Science
, vol.300
, pp. 1155-1159
-
-
Garcia-Baross, M.1
Paris, F.2
Cordon-Cardo, C.3
-
11
-
-
0036359548
-
Hypoxia - a key regulatory factor in tumour growth
-
Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
12
-
-
0142186283
-
Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomized, double-blind, placebo-controlled trial
-
Henke M, Laszing R, Rube C, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomized, double-blind, placebo-controlled trial. Lancet 2003;36:1255-60.
-
(2003)
Lancet
, vol.36
, pp. 1255-1260
-
-
Henke, M.1
Laszing, R.2
Rube, C.3
-
13
-
-
33750588816
-
Do erythropoietin receptors on cancer cells explain unexpected clinical findings?
-
Henke M, Mattern D, Pepe M, et al. Do erythropoietin receptors on cancer cells explain unexpected clinical findings? J Clin Oncol 2006;24:4708-13.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4708-4713
-
-
Henke, M.1
Mattern, D.2
Pepe, M.3
-
14
-
-
20944448672
-
Trimodal cancer treatment: Beneficial effects of combined antiangiogenesis, radiation and chemotherapy
-
Huber PE, Bischof M, Jenne J, et al. Trimodal cancer treatment: beneficial effects of combined antiangiogenesis, radiation and chemotherapy. Cancer Res 2005;65:3643-55.
-
(2005)
Cancer Res
, vol.65
, pp. 3643-3655
-
-
Huber, P.E.1
Bischof, M.2
Jenne, J.3
-
15
-
-
4544276339
-
Expression of hypoxia-inducible factor 1alpha predicts metastasis-free survival after radiation therapy alone in stage IIIB cervical squamous cell carcinoma
-
Ishikawa H, Sakurai H, Hasegawa M, et al. Expression of hypoxia-inducible factor 1alpha predicts metastasis-free survival after radiation therapy alone in stage IIIB cervical squamous cell carcinoma. Int J Radiat Oncol Biol Phys 2004;60:513-21.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.60
, pp. 513-521
-
-
Ishikawa, H.1
Sakurai, H.2
Hasegawa, M.3
-
16
-
-
0036384462
-
Erythropoietin and VEGF exhibit equal angiogenic potential
-
Jaquet K, Krause K, Tawakol-Khodai M, et al. Erythropoietin and VEGF exhibit equal angiogenic potential. Microvasc Res 2002;64:326-33.
-
(2002)
Microvasc Res
, vol.64
, pp. 326-333
-
-
Jaquet, K.1
Krause, K.2
Tawakol-Khodai, M.3
-
17
-
-
31444438853
-
The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma
-
Kirkpatrick JP, Hardee ME, Snyder SA, et al. The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma. Radiat Res 2006;165:192-201.
-
(2006)
Radiat Res
, vol.165
, pp. 192-201
-
-
Kirkpatrick, J.P.1
Hardee, M.E.2
Snyder, S.A.3
-
18
-
-
0031729893
-
Clinical trial experience using erythropoietin during radiation therapy
-
Laveys RS. Clinical trial experience using erythropoietin during radiation therapy. Strahlenther Onkol 1998;174:Suppl 4:24-30.
-
(1998)
Strahlenther Onkol
, vol.174
, Issue.SUPPL. 4
, pp. 24-30
-
-
Laveys, R.S.1
-
19
-
-
33845739772
-
-
Leo C, Horn LC, Rauscher C, et al. Expression of erythropoietin and erythropoietin receptor in cervical cancer and relationship to survival, hypoxia, and apoptosis. J Clin Cancer 2006;12:6894-900.
-
Leo C, Horn LC, Rauscher C, et al. Expression of erythropoietin and erythropoietin receptor in cervical cancer and relationship to survival, hypoxia, and apoptosis. J Clin Cancer 2006;12:6894-900.
-
-
-
-
20
-
-
0041976976
-
Breast cancer trial with erythropoietin terminated unexpectedly
-
Leyland-Jones B. Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol 2004;8:459-60.
-
(2004)
Lancet Oncol
, vol.8
, pp. 459-460
-
-
Leyland-Jones, B.1
-
21
-
-
33646120340
-
Antiangiogenic effects of radiotherapy but not initial microvessel density predict survival in inoperable oropharyngeal squamous cell carcinoma
-
Lövey J, Lukits J, Remenár E, et al. Antiangiogenic effects of radiotherapy but not initial microvessel density predict survival in inoperable oropharyngeal squamous cell carcinoma. Strahlenther Onkol 2006;182:149-56.
-
(2006)
Strahlenther Onkol
, vol.182
, pp. 149-156
-
-
Lövey, J.1
Lukits, J.2
Remenár, E.3
-
22
-
-
10644233934
-
rHuEPO and treatment outcomes: The preclinical experience
-
Ludwig H. rHuEPO and treatment outcomes: the preclinical experience. Oncologist 2004;9:48-54.
-
(2004)
Oncologist
, vol.9
, pp. 48-54
-
-
Ludwig, H.1
-
23
-
-
5344257780
-
Pretreatment normalization of mild anemia with epoetin alfa: Impact on the outcome in epithelial ovarian cancer patients
-
Marinaccio M, Mele E, Giotta F. Pretreatment normalization of mild anemia with epoetin alfa: impact on the outcome in epithelial ovarian cancer patients. Proc Am Soc Clin Oncol 2003;22:486.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 486
-
-
Marinaccio, M.1
Mele, E.2
Giotta, F.3
-
24
-
-
33644970398
-
-
Marshall DJ, Tullai J, Gechtman Z, et al. Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models. Mol Cancer Ther 2006;5:347-55.
-
Marshall DJ, Tullai J, Gechtman Z, et al. Recombinant epoetins do not stimulate tumor growth in erythropoietin receptor-positive breast carcinoma models. Mol Cancer Ther 2006;5:347-55.
-
-
-
-
26
-
-
2342611976
-
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: Role of reoxygenation, free radicals and stress granules
-
Moeller BJ, Cao Y, Li CY, et al. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals and stress granules. Cancer Cell 2004;5:429-41.
-
(2004)
Cancer Cell
, vol.5
, pp. 429-441
-
-
Moeller, B.J.1
Cao, Y.2
Li, C.Y.3
-
27
-
-
0031762534
-
Relevance of oxygen in radiation oncology. Mechanism of action, correlation to low hemoglobin levels
-
Molls M, Stadler P, Becker A, et al. Relevance of oxygen in radiation oncology. Mechanism of action, correlation to low hemoglobin levels. Strahlenther Onkol 1998;74:Suppl 4:13-6.
-
(1998)
Strahlenther Onkol
, vol.74
, Issue.SUPPL. 4
, pp. 13-16
-
-
Molls, M.1
Stadler, P.2
Becker, A.3
-
28
-
-
0035854479
-
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
-
Paris F, Fuks Z, Kang A, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001;293:293-7.
-
(2001)
Science
, vol.293
, pp. 293-297
-
-
Paris, F.1
Fuks, Z.2
Kang, A.3
-
29
-
-
33846427692
-
Radio(chemo)therapy plus resection versus radio(chemo)therapy alone for the treatment of stage III esophageal cancer
-
Rades D, Schulte R, Yekebas EF, et al. Radio(chemo)therapy plus resection versus radio(chemo)therapy alone for the treatment of stage III esophageal cancer. Strahlenther Onkol 2007;183:10-6.
-
(2007)
Strahlenther Onkol
, vol.183
, pp. 10-16
-
-
Rades, D.1
Schulte, R.2
Yekebas, E.F.3
-
30
-
-
33646245915
-
Epoetin alfa improves survival after chemoradiation for stage III esophageal cancer: Final results of a prospective observational study
-
Rades D, Tribius S, Yekebas EF, et al. Epoetin alfa improves survival after chemoradiation for stage III esophageal cancer: final results of a prospective observational study. Int J Radiat Oncol Biol Phys 2006;65:459-65.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, pp. 459-465
-
-
Rades, D.1
Tribius, S.2
Yekebas, E.F.3
-
31
-
-
0038796981
-
Prognostic implications of hemoglobin levels before and after surgery as well as before and after radiotherapy for head and neck tumors
-
Reichel O, Panzer M, Wimmer C, et al. Prognostic implications of hemoglobin levels before and after surgery as well as before and after radiotherapy for head and neck tumors. Eur Arch Otorhinolaryngol 2003;260:248-53.
-
(2003)
Eur Arch Otorhinolaryngol
, vol.260
, pp. 248-253
-
-
Reichel, O.1
Panzer, M.2
Wimmer, C.3
-
32
-
-
0033561341
-
Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo
-
Ribatti D, Marzullo A, Nico B, et al. Human erythropoietin induces a pro-angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Blood 1999;93:2627-36.
-
(1999)
Blood
, vol.93
, pp. 2627-2636
-
-
Ribatti, D.1
Marzullo, A.2
Nico, B.3
-
33
-
-
33748136112
-
Influence of pretreatment polarographically measured oxygenation levels in spontaneous canine tumors treated with radiation therapy
-
Rohrer Bley C, Ohlerth S, Roos M, et al. Influence of pretreatment polarographically measured oxygenation levels in spontaneous canine tumors treated with radiation therapy. Strahlenther Onkol 2006;182:518-24.
-
(2006)
Strahlenther Onkol
, vol.182
, pp. 518-524
-
-
Rohrer Bley, C.1
Ohlerth, S.2
Roos, M.3
-
34
-
-
0028017563
-
Recombinant human erythropoietin and the anemia of cancer
-
Spivak JL. Recombinant human erythropoietin and the anemia of cancer. Blood 1994;84:997-1004.
-
(1994)
Blood
, vol.84
, pp. 997-1004
-
-
Spivak, J.L.1
-
35
-
-
24644441023
-
Management of cancer-related anemia with erythropoietic agents: Doubts, certainties, and concerns
-
Stasi R, Amadori S, Littlewood TJ, et al. Management of cancer-related anemia with erythropoietic agents: doubts, certainties, and concerns. Oncologist 2005;10:539-54.
-
(2005)
Oncologist
, vol.10
, pp. 539-554
-
-
Stasi, R.1
Amadori, S.2
Littlewood, T.J.3
-
36
-
-
0041322520
-
Impact of anemia prevention by recombinant human erythropoietin on the sensitivity of xenografted glioblastomas to fractionated irradiation
-
Stüben G, Thews O, Pöttgen C, et al. Impact of anemia prevention by recombinant human erythropoietin on the sensitivity of xenografted glioblastomas to fractionated irradiation. Strahlenther Onkol 2003;179:620-5.
-
(2003)
Strahlenther Onkol
, vol.179
, pp. 620-625
-
-
Stüben, G.1
Thews, O.2
Pöttgen, C.3
-
37
-
-
0036731351
-
Anaemia in cancer patients: Significance, epidemiology, and current therapy
-
Tchekmedyian NS. Anaemia in cancer patients: significance, epidemiology, and current therapy. Oncology 2002;1:17-24.
-
(2002)
Oncology
, vol.1
, pp. 17-24
-
-
Tchekmedyian, N.S.1
-
38
-
-
33749133212
-
Erythropoietin administration during primary treatment for locally advanced cervical carcinoma is associated with poor response to radiation
-
Temkin SM, Hellmann M, Serur E, et al. Erythropoietin administration during primary treatment for locally advanced cervical carcinoma is associated with poor response to radiation. Int J Gynecol Cancer 2006;16:1855-61.
-
(2006)
Int J Gynecol Cancer
, vol.16
, pp. 1855-1861
-
-
Temkin, S.M.1
Hellmann, M.2
Serur, E.3
-
39
-
-
23844507094
-
Recombinant human erythropoietin alpha targets intratumoral blood vessels improving chemotherapy in human xenograft models
-
Tóvári J, Gilly R, Rásó E, et al. Recombinant human erythropoietin alpha targets intratumoral blood vessels improving chemotherapy in human xenograft models. Cancer Res 2005;65:7186-93.
-
(2005)
Cancer Res
, vol.65
, pp. 7186-7193
-
-
Tóvári, J.1
Gilly, R.2
Rásó, E.3
-
40
-
-
0034743861
-
Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
-
Vaupel P, Kelleher DK, Höckel M. Oxygenation status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 2001;28:29-35.
-
(2001)
Semin Oncol
, vol.28
, pp. 29-35
-
-
Vaupel, P.1
Kelleher, D.K.2
Höckel, M.3
-
41
-
-
31744438176
-
Impact of hemoglobin levels on tumor oxygenation: The higher, the better?
-
Vaupel P, Mayer A, Höckel M. Impact of hemoglobin levels on tumor oxygenation: the higher, the better? Strahlenther Onkol 2006;182:63-71.
-
(2006)
Strahlenther Onkol
, vol.182
, pp. 63-71
-
-
Vaupel, P.1
Mayer, A.2
Höckel, M.3
-
42
-
-
0035677961
-
Treatment resistance of solid tumors
-
Vaupel P, Thews O, Hoeckel M. Treatment resistance of solid tumors. Med Oncol 2001;18:243-59.
-
(2001)
Med Oncol
, vol.18
, pp. 243-259
-
-
Vaupel, P.1
Thews, O.2
Hoeckel, M.3
-
43
-
-
19944422751
-
Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoietin-1, and matrix metalloproteinases
-
Winkler F, Kozin SV, Tong RT, et al. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell 2004;6:553-63.
-
(2004)
Cancer Cell
, vol.6
, pp. 553-563
-
-
Winkler, F.1
Kozin, S.V.2
Tong, R.T.3
-
44
-
-
17744398006
-
Inhibition of erythropoietin signaling destroys xenografts of ovarian and uterine cancers in nude mice
-
Yasuda Y, Musha T, Tanaka H, et al. Inhibition of erythropoietin signaling destroys xenografts of ovarian and uterine cancers in nude mice. Br J Cancer 2001;84:836-43.
-
(2001)
Br J Cancer
, vol.84
, pp. 836-843
-
-
Yasuda, Y.1
Musha, T.2
Tanaka, H.3
-
45
-
-
20444435955
-
Enhanced susceptibility of irradiated tumor vessels to vascular endothelial growth factor receptor tyrosine kinase inhibition
-
Zips D, Eichler W, Geyer P, et al. Enhanced susceptibility of irradiated tumor vessels to vascular endothelial growth factor receptor tyrosine kinase inhibition. Cancer Res 2005;65:5374-9.
-
(2005)
Cancer Res
, vol.65
, pp. 5374-5379
-
-
Zips, D.1
Eichler, W.2
Geyer, P.3
|