Erythropoietin stimulates proliferation of human renal carcinoma cells

Kidney International

Volumn 58, Issue 2, 2000, Pages 647-657

  Westenfelder, C ^a   Baranowski, R L ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Anemia; Angiogenesis; Proliferating cells; Tumor malignancy; Von Hippel Lindau disease

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0033852337     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00211.x     Document Type: Article

References (66)

1. Human, rat, and mouse kidney cells express functional erythropoietin receptors
2. Erythropoietin
3. Structure, function, and activation of the erythropoietin receptor
4. Analysis of a mouse monoclonal antibody that reacts with a specific region of the human proximal tubule and subsets of renal cell carcinomas
5. Cytogenetic analysis of epithelial renal-cell tumors: Relationship with a new histopathological classification
6. Recombinant human erythropoietin stimulates angiogenesis in vitro
7. Effect of recombinant human erythropoietin on endothelial cell apoptosis
8. Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis
9. Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells
10. Erythropoietin receptor mRNA expression in human endothelial cells
11. Kidney cancer
12. Role of vascular endothelial growth factor in the regulation of angiogenesis
13. Clinical significance of erythropoietin levels in renal carcinoma
14. Renal-cell carcinoma
15. Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization
16. Peritubular cells are the site of erythropoietin synthesis in the murine hypoxia kidney
17. Identification of the renal erythropoietin-producing cells using transgenic mice
18. Erythropoietin levels in the course of a patient with erythropoietin-producing renal cell carcinoma and transplantation of this tumor in nude mice
19. Erythropoietin production in a primary culture of human renal carcinoma cells maintained in nude mice
20. Production of erythropoietin-like activity by human renal and hepatic carcinomas in cell culture
21. Stimulation by cAMP of erythropoietin secretion by an established human renal carcinoma cell line
22. Erythropoietin-induced polycythemia in athymic mice following transplantation of a human renal carcinoma cell line
23. Tumor cells are the site of erythropoietin synthesis in human renal cancers associated with polycythemia
24. Constitutive secretion of erythropoietin by human renal adenocarcinoma cells in vivo and in vitro
25. Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro
26. Erythropoietin production: A potential marker for interleukin-2/interferon-responsive tumors
27. Higher susceptibility of erythropoietin-producing renal cell carcinomas to lysis by lymphokine-activated killer cells
28. Erythropoietin in renal cell carcinoma: Evaluation of its usefulness as a tumor marker
29. Prevalence of paraneoplastic erythropoietin production by renal cell carcinomas
30. Metastatic renal cell carcinoma: Response to treatment with human recombinant erythropoietin
31. Treatment of advanced kidney cancer using recombinant erythropoietin
32. Does erythropoietin accelerate malignant transformation in multiple myeloma?
33. Renal tubular function in glycerol-induced acute renal failure
34. Tumor suppression by the human von Hippel-Lindau gene product
35. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
36. Human erythropoietin receptor: Cloning, expression, and biologic characterization
37. Developmental changes in erythropoietin expression of fetal mouse liver
38. Expression cloning of the murine erythropoietin receptor
39. Human hematopoietic progenitors express erythropoietin
40. Functional erythropoietin receptor of the cells with neural characteristics: Comparison with receptor properties of erythroid cells
41. The attractions of proteins for small molecules and ions
42. 2+ channels: Activation by phospholipase C-gamma 1
43. Urea induces the heat shock response in human neuroblastoma cells
44. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
45. Histopathology and classification of renal cell tumors (adenomas, oncocytomas and carcinomas): The basic cytological and histological elements and their use for diagnosis
46. Prognostic significance of morphologic parameters in renal cell carcinoma
47. The functional form of the erythropoietin receptor is a 78-kDa protein: Correlation with cell surface expression, endocytosis, and phosphorylation
48. Insulin- and insulin-like growth-factor-I receptor tyrosine-kinase activities in human renal cancer
49. Functional intactness of stimulatory and inhibitory autocrine loops in human renal carcinoma cell lines of the clear cell type
50. Hepatocyte growth factor-stimulated renal tubular mitogenesis: Effects on expression of c-myc, c-fos, c-met, VEGF and the VHL tumour-suppressor and related genes
51. Growth hormone-releasing hormone antagonist MZ-4-71 inhibits in vivo proliferation of Caki-I renal adenocarcinoma
52. Binding of epidermal growth factor and insulin-like growth-factor I in renal carcinoma and adjacent normal kidney tissue
53. Interleukin-6 (IL-6) functions as an in vitro autocrine growth factor in renal cell carcinoma
54. Transforming growth factor alpha is a target for the von Hippel-Lindau tumor suppressor
55. Transforming growth factor beta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma
56. The hyperresponsiveness of cells expressing truncated erythropoietin receptors is contingent on insulin-like growth factor-1 in fetal calf serum
57. Subtherapeutic erythropoietin and insulin-like growth factor-1 correct the anemia of chronic renal failure in the mouse
58. Therapeutic use of growth factors in renal failure
59. Cell-cycle-dependent regulation of erythropoietin receptor gene
60. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene
61. Gene expression of mutant erythropoietin in hepatocellular carcinoma
62. Studies on the role of recombinant human erythropoietin in the growth regulation of human nonhematopoietic tumor cells in vitro
63. Autocrine regulation of erythropoietin gene expression in human hepatocellular carcinoma cells
64. Putative oncogenic role of the erythropoietin receptor in murine and human erythroleukemia cells
65. Evidence for cytokine-inducible nitric oxide synthesis from L-arginine in patients receiving interleukin-2 therapy