메뉴 건너뛰기




Volumn 25, Issue 7, 2007, Pages 1923-1930

Recombinant human erythropoietin suppresses symptom onset and progression of G93A-SOD1 mouse model of ALS by preventing motor neuron death and inflammation

Author keywords

ALS; Erythropoietin; Inflammation; Neuronal cell death

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; EPORON; RECOMBINANT ERYTHROPOIETIN; UNCLASSIFIED DRUG;

EID: 34147199187     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2007.05471.x     Document Type: Article
Times cited : (42)

References (32)
  • 1
    • 0037064261 scopus 로고    scopus 로고
    • Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis
    • Agnello, D., Bigini, P., Villa, P., Mennini, T., Cerami, A., Brines, M.L. & Ghezzi, P. (2002) Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res., 952, 128-134.
    • (2002) Brain Res , vol.952 , pp. 128-134
    • Agnello, D.1    Bigini, P.2    Villa, P.3    Mennini, T.4    Cerami, A.5    Brines, M.L.6    Ghezzi, P.7
  • 2
    • 0035068202 scopus 로고    scopus 로고
    • Effects of an inhibitor of poly (ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice
    • Andreassen, O.A., Dedeoglu, A., Friedlich, A., Ferrante, K.L., Hughes, D., Szabo, C. & Beal, M.F. (2001) Effects of an inhibitor of poly (ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice. Exp. Neurol., 168, 419-424.
    • (2001) Exp. Neurol , vol.168 , pp. 419-424
    • Andreassen, O.A.1    Dedeoglu, A.2    Friedlich, A.3    Ferrante, K.L.4    Hughes, D.5    Szabo, C.6    Beal, M.F.7
  • 3
    • 0034763566 scopus 로고    scopus 로고
    • Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis
    • Beers, D.R., Ho, B.K., Siklos, L., Alexianu, M.E., Mosier, D.R., Mohamed, A.H., Otsuka, Y., Kozovska, M.E., McAlhany, R.E., Smith, R.G. & Appel, S.H. (2001) Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis. J. Neurochem., 79, 499-509.
    • (2001) J. Neurochem , vol.79 , pp. 499-509
    • Beers, D.R.1    Ho, B.K.2    Siklos, L.3    Alexianu, M.E.4    Mosier, D.R.5    Mohamed, A.H.6    Otsuka, Y.7    Kozovska, M.E.8    McAlhany, R.E.9    Smith, R.G.10    Appel, S.H.11
  • 4
    • 33746310289 scopus 로고    scopus 로고
    • Erythropoietin in the cerebrospinal fluid in neurodegenerative diseases
    • Brettschneider, J., Widl, K., Ehrenreich, H., Riepe, M. & Tumani, H. (2006) Erythropoietin in the cerebrospinal fluid in neurodegenerative diseases. Neurosci. Lett., 404, 347-351.
    • (2006) Neurosci. Lett , vol.404 , pp. 347-351
    • Brettschneider, J.1    Widl, K.2    Ehrenreich, H.3    Riepe, M.4    Tumani, H.5
  • 7
  • 8
    • 0024994099 scopus 로고
    • IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis
    • Engelhardt, J.I. & Appel, S.H. (1990) IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis. Arch. Neurol., 47, 1210-1216.
    • (1990) Arch. Neurol , vol.47 , pp. 1210-1216
    • Engelhardt, J.I.1    Appel, S.H.2
  • 9
    • 0027473452 scopus 로고
    • Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
    • Engelhardt, J.I., Tajti. J. & Appel, S.H. (1993) Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis. Arch. Neurol., 50, 30-36.
    • (1993) Arch. Neurol , vol.50 , pp. 30-36
    • Engelhardt, J.I.1    Tajti, J.2    Appel, S.H.3
  • 10
    • 0037087120 scopus 로고    scopus 로고
    • Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1, 2,5,6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro
    • Genc, S., Akhisaroglu, M., Kuralay, F. & Genc, K. (2002) Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1, 2,5,6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro. Neurosci. Lett., 321, 73-76.
    • (2002) Neurosci. Lett , vol.321 , pp. 73-76
    • Genc, S.1    Akhisaroglu, M.2    Kuralay, F.3    Genc, K.4
  • 12
    • 0033551794 scopus 로고    scopus 로고
    • C1qB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis
    • Grewal, R.P., Morgan, T.E. & Finch, C.E. (1999) C1qB and clusterin mRNA increase in association with neurodegeneration in sporadic amyotrophic lateral sclerosis. Neurosci. Lett., 271, 65-67.
    • (1999) Neurosci. Lett , vol.271 , pp. 65-67
    • Grewal, R.P.1    Morgan, T.E.2    Finch, C.E.3
  • 14
    • 0042528664 scopus 로고    scopus 로고
    • Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
    • Kaspar, B.K., Llado, J., Sherkat, N., Rothstein, J.D. & Gage, F.H. (2003) Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Science, 301, 839-842.
    • (2003) Science , vol.301 , pp. 839-842
    • Kaspar, B.K.1    Llado, J.2    Sherkat, N.3    Rothstein, J.D.4    Gage, F.H.5
  • 15
    • 1942486792 scopus 로고    scopus 로고
    • Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
    • Kieran, D., Kalmar, B., Dick, J.R., Riddoch-Contreras, J., Burnstock, G. & Greensmith, L. (2004) Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat. Med., 10, 402-405.
    • (2004) Nat. Med , vol.10 , pp. 402-405
    • Kieran, D.1    Kalmar, B.2    Dick, J.R.3    Riddoch-Contreras, J.4    Burnstock, G.5    Greensmith, L.6
  • 16
    • 0942287666 scopus 로고    scopus 로고
    • Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
    • Klivenyi, P., Kiaei, M., Gardian, G., Calingasan, N.Y. & Beal, M.F. (2004) Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurochem., 88, 576-582.
    • (2004) J. Neurochem , vol.88 , pp. 576-582
    • Klivenyi, P.1    Kiaei, M.2    Gardian, G.3    Calingasan, N.Y.4    Beal, M.F.5
  • 18
    • 23944442778 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase activator reduces motor neuronal cell death induced by G93A or A4V mutant SOD1 gene
    • Koh, S.H., Roh, H., Lee, S.M., Kim, H.J., Kim, M., Lee, K.W., Kim, H.T., Kim, J. & Kim, S.H. (2005) Phosphatidylinositol 3-kinase activator reduces motor neuronal cell death induced by G93A or A4V mutant SOD1 gene. Toxicology, 213, 45-55.
    • (2005) Toxicology , vol.213 , pp. 45-55
    • Koh, S.H.1    Roh, H.2    Lee, S.M.3    Kim, H.J.4    Kim, M.5    Lee, K.W.6    Kim, H.T.7    Kim, J.8    Kim, S.H.9
  • 19
    • 0037381851 scopus 로고    scopus 로고
    • Efficient three-drug cocktail for disease induced by mutant superoxide dismutase
    • Kriz, J., Gowing, G. & Julien, J.P. (2003) Efficient three-drug cocktail for disease induced by mutant superoxide dismutase. Ann. Neurol., 53, 429-436.
    • (2003) Ann. Neurol , vol.53 , pp. 429-436
    • Kriz, J.1    Gowing, G.2    Julien, J.P.3
  • 20
    • 0024997449 scopus 로고
    • Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis
    • Lampson, L.A., Kushner, P.D. & Sobel, R.A. (1990) Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis. Ann. Neurol., 28, 365-372.
    • (1990) Ann. Neurol , vol.28 , pp. 365-372
    • Lampson, L.A.1    Kushner, P.D.2    Sobel, R.A.3
  • 21
    • 0027424082 scopus 로고
    • Erythropoietin induces the association of phosphatidylinositol 3′-kinase with a tyrosine-phosphorylated protein complex containing the erythropoietin receptor
    • Mayeux, P., Dusanter-Fourt, I., Muller, O., Mauduit, P., Sabbah, M., Druker, B., Vainchenker, W., Fischer, S., Lacombe, C. & Gisselbrecht, S. (1993) Erythropoietin induces the association of phosphatidylinositol 3′-kinase with a tyrosine-phosphorylated protein complex containing the erythropoietin receptor. Eur. J. Biochem., 216, 821-828.
    • (1993) Eur. J. Biochem , vol.216 , pp. 821-828
    • Mayeux, P.1    Dusanter-Fourt, I.2    Muller, O.3    Mauduit, P.4    Sabbah, M.5    Druker, B.6    Vainchenker, W.7    Fischer, S.8    Lacombe, C.9    Gisselbrecht, S.10
  • 22
    • 33746191379 scopus 로고    scopus 로고
    • Erythropoietin and GDNF enhance ventral mesencephalic fiber outgrowth and capillary proliferation following neural transplantation in a rodent model of Parkinson's disease
    • McLeod, M., Hong, M., Mukhida, K., Sadi, D., Ulalia, R. & Mendez, I. (2006) Erythropoietin and GDNF enhance ventral mesencephalic fiber outgrowth and capillary proliferation following neural transplantation in a rodent model of Parkinson's disease. Eur. J. Neurosci., 24, 361-370.
    • (2006) Eur. J. Neurosci , vol.24 , pp. 361-370
    • McLeod, M.1    Hong, M.2    Mukhida, K.3    Sadi, D.4    Ulalia, R.5    Mendez, I.6
  • 23
    • 0019184745 scopus 로고
    • Induction of erythropoiesis with erythrocyte production in bone marrow cell culture 'in vitro'
    • Mori, K.J., Smadja-Joffe, F., Dorval, T. & Jasmin, C. (1980) Induction of erythropoiesis with erythrocyte production in bone marrow cell culture 'in vitro'. Biomedicine, 33, 148-150.
    • (1980) Biomedicine , vol.33 , pp. 148-150
    • Mori, K.J.1    Smadja-Joffe, F.2    Dorval, T.3    Jasmin, C.4
  • 24
    • 0037146944 scopus 로고    scopus 로고
    • Early decrease of survival factors and DNA repair enzyme in spinal motor neurons of presymptomatic transgenic mice that express a mutant SOD1 gene
    • Nagano, I., Murakami, T., Manabe, Y. & Abe, K. (2002) Early decrease of survival factors and DNA repair enzyme in spinal motor neurons of presymptomatic transgenic mice that express a mutant SOD1 gene. Life Sci., 72, 541-548.
    • (2002) Life Sci , vol.72 , pp. 541-548
    • Nagano, I.1    Murakami, T.2    Manabe, Y.3    Abe, K.4
  • 25
    • 0037389393 scopus 로고    scopus 로고
    • A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis
    • Pompl, P.N., Ho, L., Bianchi, M., McManus, T., Qin, W. & Pasinetti, G.M. (2003) A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. FASEB J., 17, 725-727.
    • (2003) FASEB J , vol.17 , pp. 725-727
    • Pompl, P.N.1    Ho, L.2    Bianchi, M.3    McManus, T.4    Qin, W.5    Pasinetti, G.M.6
  • 26
    • 0034623301 scopus 로고    scopus 로고
    • iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis
    • Sasaki, S., Shibata, N., Komori, T. & Iwata, M. (2000) iNOS and nitrotyrosine immunoreactivity in amyotrophic lateral sclerosis. Neurosci. Lett., 291, 44-48.
    • (2000) Neurosci. Lett , vol.291 , pp. 44-48
    • Sasaki, S.1    Shibata, N.2    Komori, T.3    Iwata, M.4
  • 28
    • 23244446460 scopus 로고    scopus 로고
    • Neonatal hypoxia/ischemia is associated with decreased inflammatory mediators after erythropoietin administration
    • Sun, Y., Calvert, J.W. & Zhang, J.H. (2005) Neonatal hypoxia/ischemia is associated with decreased inflammatory mediators after erythropoietin administration. Stroke, 36, 1672-1678.
    • (2005) Stroke , vol.36 , pp. 1672-1678
    • Sun, Y.1    Calvert, J.W.2    Zhang, J.H.3
  • 30
    • 0034811953 scopus 로고    scopus 로고
    • Early decrease of survival signal-related proteins in spinal motor neurons of presymptomatic transgenic mice with a mutant SOD1 gene
    • Warita, H., Manabe, Y., Murakami, T., Shiro, Y., Nagano, I. & Abe, K. (2001) Early decrease of survival signal-related proteins in spinal motor neurons of presymptomatic transgenic mice with a mutant SOD1 gene. Apoptosis, 6, 345-352.
    • (2001) Apoptosis , vol.6 , pp. 345-352
    • Warita, H.1    Manabe, Y.2    Murakami, T.3    Shiro, Y.4    Nagano, I.5    Abe, K.6
  • 32
    • 4844227301 scopus 로고    scopus 로고
    • Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS
    • Zheng, C., Nennesmo, I., Fadeel, B. & Henter, J.I. (2004) Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS. Ann. Neurol., 56, 564-567. .
    • (2004) Ann. Neurol , vol.56 , pp. 564-567
    • Zheng, C.1    Nennesmo, I.2    Fadeel, B.3    Henter, J.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.