메뉴 건너뛰기




Volumn 117, Issue 18, 2011, Pages 4905-4914

Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; MESSENGER RNA; OXYGEN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HIF 2; UNCLASSIFIED DRUG;

EID: 79955963946     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-07-298083     Document Type: Article
Times cited : (43)

References (44)
  • 2
    • 0026526168 scopus 로고
    • Erythropoietin: Structure, control of production, and function
    • Jelkmann W. Erythropoietin: structure, control of production, and function. Physiol Rev. 1992; 72(2):449-489.
    • (1992) Physiol Rev , vol.72 , Issue.2 , pp. 449-489
    • Jelkmann, W.1
  • 4
    • 0027410945 scopus 로고
    • Co-localization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin
    • Bachmann S, Le Hir M, Eckardt KU. Colocalization of erythropoietin mRNA and ecto- 5′-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem. 1993;41(3):335-341. (Pubitemid 23061919)
    • (1993) Journal of Histochemistry and Cytochemistry , vol.41 , Issue.3 , pp. 335-341
    • Bachmann, S.1    Le, H.M.2    Eckardt, K.-U.3
  • 8
    • 77952690589 scopus 로고    scopus 로고
    • Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
    • Wenger RH, Hoogewijs D. Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells. Am J Physiol Renal Physiol. 2010;298(6):F1287-F1296.
    • (2010) Am J Physiol Renal Physiol , vol.298 , Issue.6
    • Wenger, R.H.1    Hoogewijs, D.2
  • 9
  • 10
    • 67650531089 scopus 로고    scopus 로고
    • Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts
    • Mole DR, Blancher C, Copley RR, et al. Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts. J Biol Chem. 2009;284(25):16767- 16775.
    • (2009) J Biol Chem , vol.284 , Issue.25 , pp. 16767-16775
    • Mole, D.R.1    Blancher, C.2    Copley, R.R.3
  • 11
    • 36849049298 scopus 로고    scopus 로고
    • Hypoxia and the HIF system in kidney disease
    • DOI 10.1007/s00109-007-0278-y, Special Issue (Ed. G. Semenza): Hypoxia and Human Disease
    • Nangaku M, Eckardt KU. Hypoxia and the HIF system in kidney disease. J Mol Med. 2007; 85(12):1325-1330. (Pubitemid 50004091)
    • (2007) Journal of Molecular Medicine , vol.85 , Issue.12 , pp. 1325-1330
    • Nangaku, M.1    Eckardt, K.-U.2
  • 15
    • 77958177671 scopus 로고    scopus 로고
    • Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
    • Kapitsinou PP, Liu Q, Unger TL, et al. Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. Blood. 2010;116(16):3039- 3048.
    • (2010) Blood , vol.116 , Issue.16 , pp. 3039-3048
    • Kapitsinou, P.P.1    Liu, Q.2    Unger, T.L.3
  • 16
    • 44749093281 scopus 로고    scopus 로고
    • The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors
    • Warnecke C, Weidemann A, Volke M, et al. The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors. Exp Cell Res. 2008;314(10): 2016-2027.
    • (2008) Exp Cell Res , vol.314 , Issue.10 , pp. 2016-2027
    • Warnecke, C.1    Weidemann, A.2    Volke, M.3
  • 19
    • 0028913911 scopus 로고
    • Human renal fibroblast cell lines (tFKIF and tNKF) are new tools to investigate pathophysiologic mechanisms of renal interstitial fibrosis
    • Müller GA, Frank J, Rodemann HP, Engler-Blum G. Human renal fibroblast cell lines (tFKIF and tNKF) are new tools to investigate pathophysiologic mechanisms of renal interstitial fibrosis. Exp Nephrol. 1995;3(2):127-133.
    • (1995) Exp Nephrol , vol.3 , Issue.2 , pp. 127-133
    • Müller, G.A.1    Frank, J.2    Rodemann, H.P.3    Engler-Blum, G.4
  • 20
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • Chomczynski P, Sacchi N. Single-step method of RNAisolation by acid guanidinium thiocyanatephenol-chloroform extraction. Anal Biochem. 1987;162(1):156-159. (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 21
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucl Acids Res. 1989;17(15):6419.
    • (1989) Nucl Acids Res , vol.17 , Issue.15 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 22
    • 0025337049 scopus 로고
    • Human erythropoietin receptor: Cloning, expression, and biologic characterization
    • Jones SS, D'Andrea AD, Haines LL, Wong GG. Human erythropoietin receptor: cloning, expression, and biologic characterization. Blood. 1990; 76(1):31-35. (Pubitemid 20220787)
    • (1990) Blood , vol.76 , Issue.1 , pp. 31-35
    • Jones, S.S.1    D'Andrea, A.D.2    Haines, L.L.3    Wong, G.G.4
  • 23
    • 0028967752 scopus 로고
    • The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1
    • Galson DL, Tsuchiya T, Tendler DS, et al. The orphan receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1. Mol Cell Biol. 1995;15(4):2135-2144.
    • (1995) Mol Cell Biol , vol.15 , Issue.4 , pp. 2135-2144
    • Galson, D.L.1    Tsuchiya, T.2    Tendler, D.S.3
  • 24
    • 7444253390 scopus 로고    scopus 로고
    • Beneficial and ominous aspects of the pleiotropic action of erythropoietin
    • DOI 10.1007/s00277-004-0911-6
    • Jelkmann W, Wagner K. Beneficial and ominous aspects of the pleiotropic action of erythropoietin. Ann Hematol. 2004;83(11):673-686. (Pubitemid 39440211)
    • (2004) Annals of Hematology , vol.83 , Issue.11 , pp. 673-686
    • Jelkmann, W.1    Wagner, K.2
  • 25
  • 27
    • 0023868741 scopus 로고
    • Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization
    • Koury ST, Bondurant MC, Koury MJ. Localization of erythropoietin synthesizing cells in murine kidneys by in situ hybridization. Blood. 1988;71(2): 524-527. (Pubitemid 18089550)
    • (1988) Blood , vol.71 , Issue.2 , pp. 524-527
    • Koury, S.T.1    Bondurant, M.C.2    Koury, M.J.3
  • 28
    • 0028816847 scopus 로고
    • Purification and characterization of hypoxia-inducible factor 1
    • Wang GL, Semenza GL. Purification and characterization of hypoxia-inducible factor 1. J Biol Chem. 1995;270(3):1230-1237.
    • (1995) J Biol Chem , vol.270 , Issue.3 , pp. 1230-1237
    • Wang, G.L.1    Semenza, G.L.2
  • 29
    • 0032190614 scopus 로고    scopus 로고
    • 2 homeostasis
    • DOI 10.1016/S0959-437X(98)80016-6
    • Semenza GL. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. Curr Opin Genet Dev. 1998;8(5):588-594. (Pubitemid 28477364)
    • (1998) Current Opinion in Genetics and Development , vol.8 , Issue.5 , pp. 588-594
    • Semenza, G.L.1
  • 32
    • 46749127450 scopus 로고    scopus 로고
    • Repression via the GATA box is essential for tissue-specific erythropoietin gene expression
    • Obara N, Suzuki N, Kim K, et al. Repression via the GATA box is essential for tissue-specific erythropoietin gene expression. Blood. 2008; 111(10):5223-5232.
    • (2008) Blood , vol.111 , Issue.10 , pp. 5223-5232
    • Obara, N.1    Suzuki, N.2    Kim, K.3
  • 33
    • 0026049416 scopus 로고
    • Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene
    • Beck I, Ramirez S, Weinmann R, Caro J. Enhancer element at the 3′-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene. J Biol Chem. 1991;266(24): 15563-15566. (Pubitemid 21907687)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.24 , pp. 15563-15566
    • Beck, I.1    Ramirez, S.2    Weinmann, R.3    Caro, J.4
  • 34
    • 70449527373 scopus 로고    scopus 로고
    • Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing
    • Webb JD, Coleman ML, Pugh CW. Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing. Cell Mol Life Sci. 2009; 66(22):3539-3554.
    • (2009) Cell Mol Life Sci , vol.66 , Issue.22 , pp. 3539-3554
    • Webb, J.D.1    Coleman, M.L.2    Pugh, C.W.3
  • 35
    • 9444283176 scopus 로고    scopus 로고
    • Differentiating the functional role of hypoxia-inducible factor (HIF)-1α and HIF-2α (EPAS-1) by the use of RNA interference: Erythropoietin is a HIF-2α target gene in Hep3B and Kelly cells
    • DOI 10.1096/fj.04-1640fje
    • Warnecke C, Zaborowska Z, Kurreck J, et al. Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J. 2004;18(12):1462-1464. (Pubitemid 39561615)
    • (2004) FASEB Journal , vol.18 , Issue.12 , pp. 1462-1464
    • Warnecke, C.1    Zaborowska, Z.2    Kurreck, J.3    Erdmann, V.A.4    Frei, U.5    Wiesener, M.6    Eckardt, K.-U.7
  • 36
    • 75749150800 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
    • Paliege A, Rosenberger C, Bondke A, et al. Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization. Kidney Int. 2010;77(4):312-318.
    • (2010) Kidney Int , vol.77 , Issue.4 , pp. 312-318
    • Paliege, A.1    Rosenberger, C.2    Bondke, A.3
  • 37
    • 0036786965 scopus 로고    scopus 로고
    • Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells
    • Stolze I, Berchner-Pfannschmidt U, Freitag P, et al. Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells. Blood. 2002; 100(7):2623-2628.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2623-2628
    • Stolze, I.1    Berchner-Pfannschmidt, U.2    Freitag, P.3
  • 38
    • 0037414180 scopus 로고    scopus 로고
    • YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1
    • Yeo EJ, Chun YS, Cho YS, et al. YC-1: A potential anticancer drug targeting hypoxia-inducible factor 1. J Natl Cancer Inst. 2003;95(7):516-525.
    • (2003) J Natl Cancer Inst , vol.95 , Issue.7 , pp. 516-525
    • Yeo, E.J.1    Chun, Y.S.2    Cho, Y.S.3
  • 40
    • 33847307112 scopus 로고    scopus 로고
    • Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2
    • DOI 10.1074/jbc.M607065200
    • Berchner-Pfannschmidt U, Yamac H, Trinidad B, Fandrey J. Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2. J Biol Chem. 2007;282(3):1788-1796. (Pubitemid 47076719)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.3 , pp. 1788-1796
    • Berchner-Pfannschmidt, U.1    Yamac, H.2    Trinidad, B.3    Fandrey, J.4
  • 42
    • 23944454868 scopus 로고    scopus 로고
    • Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene
    • DOI 10.1042/BJ20042121
    • Pescador N, Cuevas Y, Naranjo S, et al. Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene. Biochem J. 2005; 390(1):189-197. (Pubitemid 41192244)
    • (2005) Biochemical Journal , vol.390 , Issue.1 , pp. 189-197
    • Pescador, N.1    Cuevas, Y.2    Naranjo, S.3    Alcaide, M.4    Villar, D.5    Landazuri, M.O.6    Del, P.L.7
  • 44
    • 0025974107 scopus 로고
    • Regulatory elements of the erythropoietin gene
    • Imagawa S, Goldberg MA, Doweiko J, Bunn HF. Regulatory elements of the erythropoietin gene. Blood. 1991;77(2):278-285.
    • (1991) Blood , vol.77 , Issue.2 , pp. 278-285
    • Imagawa, S.1    Goldberg, M.A.2    Doweiko, J.3    Bunn, H.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.