Exposure of endothelial cells to recombinant human erythropoietin induces nitric oxide synthase activity

Kidney International

Volumn 57, Issue 5, 2000, Pages 1895-1904

  Banerjee, Debendranath ^a   Rodriguez, Marilis ^a   Nag, Mihir ^a   Adamson, John W ^a  

^a Lindsley F Kimball Res Institute   (United States)

Author keywords

Anemia; Chronic renal failure; Endothelin; Erythropoietin; Nitric oxide; Receptor

Indexed keywords

NITRIC OXIDE SYNTHASE; RECOMBINANT ERYTHROPOIETIN;

ARTICLE; CHRONIC KIDNEY FAILURE; DISEASE ASSOCIATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG SAFETY; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; HYPERTENSION; PRIORITY JOURNAL;

EID: 0034068673     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00039.x     Document Type: Article

References (57)

1. 1. KRANTZ SB: Erythropoietin. Blood 77:419-434, 1991
2. 2. JELKMANN W: Erythropoietin: Structure, control of production, and function. Physiol Rev 72:449-489, 1992
3. 3. BAZAN JF: Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 87:6934-6938, 1990
4. 4. D'ANDREA AD, LODISH HF, WONG GG: Expression cloning of the murine eythropoietin receptor. Cell 57:277-285, 1989
5. 5. WU H, LIU X, JAENISCH R, LODISH HF: Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 83:59-67, 1995
6. 6. LIN CS, LIM SK, D'AGATI V, COSTANTINI F: Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev 10:154-164, 1996
7. 7. ORLIC D, ANDERSON S, BIESECKER LG, SORRENTINO BP, BODINE DM: Pluripotent hematopoietic stem cells contain high levels of mRNA for c-kit, GATA-2, p45, NF-E2, and c-myb and low levels or no mRNA for c-fms and the receptors for granulocyte colony-stimulating factor and interleukins 5 and 7. Proc Natl Acad Sci USA 92:4601-4605, 1995
8. 8. ANAGNOSTOU A, LEE ES, KESSIMIAN N, LEVINSON R, STEINER M: Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells. Proc Natl Acad Sci USA 87:5978-5982, 1990
9. 9. ANAGNOSTOU A, LIU Z, STEINER M, CHIN K, LEE ES, KESSIMIAN N, NOGUCHI CT: Erythropoietin receptor mRNA expression in human endothelial cells. Proc Natl Acad Sci USA 91:3974-3978, 1994
10. 10. YAMAJI R, OKADA T, MORIYA M, NAITO M, TSURUO T, MIYATAKE K, NAKANO Y: Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA. Eur J Biochem 239:494-500, 1996
11. 11. MORISHITA E, MASUDA M, NAGAO M, YASUDA Y, SASAKI, R: Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death. Neuroscience 76:105-116, 1997
12. 12. MORISHHA E, NARITA H, NISHIDA M, KAWASHIMA N, YAMAGISHI K, MASUDA S, NAGAO M, HAITA H, SASAKI R: Anti-erythropoietin receptor monoclonal antibody: Epitope mapping, quantification of the soluble receptor and detection of the solubilized transmembrane receptor and the receptor expressing cells. Blood 88:465-471, 1996
13. 13. DIGICAYLIOGLU M, BICHFT S, MARTI HH, WENGER RH, RIVAS LA, BAUER C, GASSMANN M: Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proc Natl Acad Sci USA 92:3717-3720, 1995
14. 14. YASUDA Y, MASUDA S, CHIKUMA M, INOUE K, NAGAO M, SASAKI R: Estrogen-dependent production of erythropoietin in uterus and its implication in uterine angiogenesis. J Biol Chem 273:25381-25387, 1998
15. 15. CARLINI RG, REYES AA, ROTHSTEIN M: Recombinant human erythropoietin stimulates angiogenesis in vitro. Kidney Int 47:740-745, 1995
16. 16. BODE-BOGER SM, BODGER RH, KUHN M, RADERMACHER J, FROLICH JC: Endothelin release and shift in prostaglandin balance are involved in the modulation of vascular tone by recombinant erythropoietin. J Cardiovasc Pharmacol 20:25-28, 1992
17. 17. CARAVACA F, PIZARRO JL, ARROBAS M, CUBERO JJ, GARCIA MC, PEREZ-MIRANDA M: Antiplatelet therapy and development of hypertension induced by recombinant human erythropoietin in uremic patients. Kidney Int 45:845-851, 1994
18. 18. RAINE A, ROGER S: Effects of erythropoietin on blood pressure. Am J Kidney Dis 18:76-83, 1991
19. 19. STEFFEN HM, BRUNNER R, MULLER R, DEGENHARDT S, POLLOK M, LANG R, BALDAMUS CA: Peripheral hemodynamics, blood viscosity and the renin-angiotensin system in hemodialysis patients under therapy with recombinant human erythropoietin. Contrib Nephrol 76:292-298, 1989
20. 20. DUKE M, ABELMAN W: The hemodynamic response to chronic anemia. Circulation 39:503-515, 1969
21. 21. HEIDENREICH S, RAHN KH, ZIDEK W: Direct vasopressor effect of recombinant human erythropoietin on renal resistance vessels. Kidney Int 39:259-265, 1991
22. 22. TEPEL M, WISCHNIOWSKI H, ZIDEK W: Erythropoietin increases cytosolic free calcium concentration and thrombin induced changes in cytosolic free calcium in platelets from spontaneously hypertensive rats. Biochem Biophys Res Commun 177:991-997, 1991
23. 23. MILLER BA, BELL LL, LYNCH CJ, CHEUNG JY: Erythropoietin modulation of intracellular calcium: A role for tyrosine phosphorylation. Cell Calcium 16:481-490, 1994
24. 24. AUGUSTIN HG, KOZIAN DH, JOHNSON RC: Differentiation of endothelial cells: Analysis of the constitutive and activated endothelial cell phenotypes. Bioessays 16:901-906, 1994
25. 25. DEJANA E: Endothelial adherens junctions: Implications in the control of vascular permeability and angiogenesis. J Clin Invest 98:1949-1953, 1996
26. 26. FURCHGOTT RF: Role of endothelium in responses of vascular smooth muscle. Circ Res 53:557-573, 1983
27. 27. FURCHGOTT RF: The role of endothelium in responses of vascular smooth muscle to drugs. Annu Rev Pharmacol Toxicol 24:175-197, 1984
28. 28. PALMER RM, FERRIGE AG, MONCADA S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327:524-526, 1987
29. 29. DE MEY JG, VANHOUTTE PM: Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium. Circ Res 51:439-447, 1982
30. 30. HARDER DR: Pressure-induced myogenic activation of cat cerebral arteries is dependent on intact endothelium. Circ Res 60:102-107, 1987
31. 31. KATUSIC ZS, SHEPHERD JT, VANHOUTTE PM: Endothelium-dependent contraction to stretch in canine basilar arteries. Am J Physiol 252:H671-H673, 1987
32. 32. YANAGISAWA M, KURIHARA H, KIMURA S, TOMOBE Y, KOBAYASHI M, MITSUI Y, YAZAKI Y, GOTO K, MASAKI T: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415, 1988
33. 33. CLOZEL M, FISCHLI W: Human cultured endothelial cells do secrete endothelin-1. J Cardiovasc Pharmacol 13(Suppl 5):S229-S231, 1989
34. 34. MARSDEN PA, DANTHULURI NR, BRENNER BM, BALLERMAN BJ, BROCK TA: Endothelin action on vascular smooth muscle involves inositol triphosphate and calcium mobilization. Biochem Biophys Res Commun 158:86-93, 1989
35. 35. HIGHSMITH RF, PANG DC, RAPOPORT RM: Endothelial cell derived vasoconstrictors: Mechanism of action in vascular smooth muscle. J Cardiovasc Pharmacol 13(Suppl 5):S36-S44, 1989
36. 36. NOGUCHI CT, BAE KS, CHIN K, WADA Y, SCHECHTER AN, HANKINS WD: Cloning of the human erythropoietin. Blood 78:2548-2556, 1991
37. 37. BLOCH KD, FRIEDRICH SP, LEE MN, EDDY RL, SHOWS TB, QUERTERMOUS T: Structural organization and chromosomal assignment of the gene encoding endothelin. J Biol Chem 264:10851-10857, 1989
38. 38. MARSDEN PA, HENG HHQ, SCHERER SW, STEWART RJ, HALL AV, SHI XM, TSUI LC, SCHAPPERT KT: Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 268:17478-17488, 1993
39. 39. CARLINI RG, DUSSO AS, OBIALO CI, ALVAREZ UM, ROTHSTEIN M: Recombinant human erythropoietin (rHuEPO) increases endothelin-1 release by endothelial cells. Kidney Int 43:1010-1014, 1993
40. 40. DUSTING GJ: Nitric oxide in cardiovascular disorders. J Vasc Res 32:143-161, 1995
41. 41. WENNMALM A: Endothelial nitric oxide and cardiovascular disease. J Intern Med 235:317-327, 1994
42. 42. DECATERINA R, LIBBY P, THANNICKAL VJ, PENG HB, RAJAVASHISTH TB, GIMBRONE MA JR, SHIN WS, LIAO JK: Nitric oxide decreases cytokine-induced endothelial activation: Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines. J Clin Invest 96:60-68, 1995
43. 43. BROUDY VC, LIN N, EGRIE J, DE HUEN C, WEISS T, PAPAYANNOPOULOU T, ADAMSON JW: Identification of the receptor for erythropoietin on human and murine erythroleukemia cells and modulation by phorbol ester and dimethyl sulfoxide. Proc Natl Acad Sci USA 85:6513-6517, 1988
44. 44. TODOKORO K, KANAZAWA S, AMANUMA H, IKAWA Y: Specific binding of erythropoietin to its receptor on responsive mouse erythroleukemia cells. Proc Natl Acad Sci USA 84:4126-4130, 1987
45. 45. FRASER JK, NICHOLLS J, COFFEY C, LIN FK, BERRIDGE MV: Down-modulation of high-affinity receptors for erythropoietin on murine erythroblasts by interleukin 3. Exp Hematol 16:769-773, 1988
46. 46. KRANTZ SB, SAWYER ST, SAWADA KI: Purification of erythroid progenitor cells and characterization of erythropoietin receptors. Br J Cancer 58(Suppl 9):31-35, 1988
47. 47. NAGAO M, MATSUMOTO S, MASUDA S, SASAKI R: Effect of tunicamycin treatment on ligand binding to the erythropoietin receptor: Conversion from two classes of binding sites to a single class. Blood 81:2503-2510, 1993
48. 48. FLAMME I, RISAU W: Introduction of vasculogenesis and hematopoiesis in vitro. Development 116:435-439, 1992
49. 49. ASAHARA T, MUROHARA T, SULLIVAN A, SILVER M, VAN DER ZEE R, LI T, WITZENBICHLER B, SCHATTEMAN G, ISNER JM: Isolation of putative progenitor endothelial cells for angiogenesis. Science 275:964-967, 1997
50. 50. YOUSSOUFIAN H, LONGMORE G, NEUMANN D, YOSHIMURA A, LODISH HF: Structure, function and activation of the erythropoietin receptor. Blood 81:2223-2236, 1993
51. 51. NEUMANN D, WIKSTROM L, WATOWICH SC, LODISH HF: Intermediates in degradation of the erythropoietin receptor accumulate and are degraded in lysosomes. J Biol Chem 268:13639-13649, 1993
52. 52. CINES DB, POLLAK ES, BUCK CA, LOSCALZO J, ZIMMERMAN GA, MCEVER RP, POBER JS, WICK TM, KONKLE BA, SCHWARTZ BS, BARNATHAN ES, MCCRAE KR, HUG BA, SCHMIDT AM, STERN DM: Endothelial cells in physiology and in the pathophysiology of vascular disorders. Blood 91:3527-3561, 1998
53. 53. LEVIN ER: Endothelins. N Engl J Med 333:356-363, 1996
54. 54. NAKAMURA S, NARUSE M, MARUSE K, DEMURA H, UEMURA H: Immunochemical localization of endothelin in cultured bovine endothelial cell. Histochemistry 94:475-477, 1990
55. 55. STAMLER JS, SINGEL DJ, LOSCALZO J: Biochemistry of nitric oxide and its redox-activaled forms. Science 258:1898-1902, 1992
56. 56. TOPPER JN, CAI J, FALB D, GIMBRONE MA JR: Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: Cyclooxygenase-3, manganese Superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress. Proc Natl Acad Sci USA 93:10417-10422, 1996
57. 57. BUEMI M, ALLEGRA A, FRISINA N: Eritropoietina: Non solo anemia renale. G Ital Nefrol 12:9-15, 1995