Erythropoiesis in myelodysplastic syndrome: Expression of receptors for erythropoietin and kit ligand

Leukemia

Volumn 10, Issue 3, 1996, Pages 466-472

  Backx, B ^a   Broeders, L ^a   Hoefsloot, L H ^b   Wognum, B ^b   Lowenberg B ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

c kit; EPO R; Erythropoiesis; Myelodysplastic syndrome

Indexed keywords

CD34 ANTIGEN; CYTOKINE RECEPTOR; ERYTHROPOIETIN RECEPTOR; RECEPTOR SUBTYPE; STEM CELL FACTOR;

ADULT; AGED; ARTICLE; BONE MARROW CELL; CLINICAL ARTICLE; COLONY FORMATION; ERYTHROPOIESIS; FEMALE; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; MALE; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0029960947     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Koeffler HP. Myelodysplastic syndromes (preleukemia). Semin Hematol 1986; 23: 284-299.
2. Layton DM, Mufti GJ. Myelodysplastic syndromes: their history, evolution and relation to actue myeloid leukemia. Blut 1986; 53: 423-436.
3. Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DAG, Gralnick HR, Sultan C, the French-American-British (FAB) cooperative group. Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 1982; 51: 189-199.
4. Janssen JWG, Buschle M, Layton M, Drexler HG, Lyons J, van den Berghe H, Heimpel H, Kubanek B, Kleihauer E, Mufti GJ, Bartram CR. Clonal evidence of myelodysplastic syndromes: evidence of multipotent stem cell origin. Blood 1989; 73: 248-254
5. Tefferi A, Thibodeau SN, Solberg LA Jr. Clonal studies in the myelodysplastic syndrome using X-linked restriction fragment length polymorphism. Blood 1990; 75: 1770-1773.
6. Yunis JJ, Rydell RE, Oken MM, Arnesen MA, Mayer MG, Lobell M. Refined chromosome analysis as an independent prognostic indicator in de novo myelodysplastic syndrome. Blood 1986; 67: 1721-1730.
7. Yunis JJ, Lobell M, Arnesen MA, Oken MM, Mayer MG, Rydell RE, Brunning RD. Refined chromosome study helps define prognostic subgroups in most patients with primary myelodysplastic syndrome and acute myelogenous leukemia. Br J Haematol 1988; 68: 189-194.
8. Mayani H, Baines P, Bowen DT, Jacobs A. In vitro growth of myeloid and erythroid progenitor cells from myelodysplastic patients in response to recombinant human granulocyte-macrophage colony stimulating factor. Leukemia 1989; 3: 29-32.
9. Merchav S, Nagler A, Fleischer-Kurtz G, Tatarsky I. Regulatory abnormalities in the marrow of patients with myelodysplastic syndromes. Br J Haematol 1989; 73: 158-164.
10. Merchav S, Wagemaker G, Souza LM, Tatarsky I. Impaired response of myelodysplastic marrow progenitors to stimulation with recombinant haemopoietic growth factors. Leukemia 1991; 5: 340-346.
11. Asano H, Hotta T, Ichihara M, Murate T, Kobayashi M, Saito H. Growth analysis of marrow CD34-positive hematopoietic progenitor cells in patients with myelodysplastic syndromes. Leukemia 1994; 8: 833-838.
12. Merchav S, Nielsen OJ, Rosenbaum H, Sharon R, Brenner B, Tatarsky I, Scigalla P, Wieczorek L. In vitro studies of erythropoietin dependent regulation of erythropoiesis in myelodysplastic syndromes. Leukemia 1990; 4: 771-774.
13. Juvonen E, Ruutu T. Effect of culture conditions on in vitro erythroid colony formation in myelodysplastic syndromes. Exp Haematol 1990; 18: 1070-1072.
14. Schouten HC, Vellenga E, van Rhenen DJ, de Wolf JT, Coppens PJ, Blijham GH. Recombinant human erythropoietin in patients with myelodysplastic syndromes. Leukemia 1991; 5: 432-436.
15. Jacobs A, Janowska-Wieczorek A, Caro J, Bowen DT, Lewis T. Circulating erythropoietin in patients with myelodysplastic syndrome. Br J Haematol 1989; 73: 36-39.
16. Bowen D, Cullilgan D, Jacobs A. The treatment in the myelodysplastic syndromes with recombinant human erythropoietin. Br J Haematol 1991; 77: 419-423.
17. Stein RS, Abels RI, Krantz SB. Pharamcologic doses of recombinant human erythropoietin in the treatment of myelodysplastic syndromes. Blood 1991; 78: 1658-1663.
18. Nakamura Y, Komatsu N, Nakauchi H. A truncated erythropoietin receptor that fails to prevent programmed cell death of erythroid cells. Science 1992; 257: 1138-1141.
19. Nakamura Y. A truncated erythropoietin receptor and cell death: a reanalysis. Science 1994; 264: 588-589.
20. Witte ON. Steel locus defines new multipotent growth factor. Cell 1990; 63: 5-6.
21. Huang E, Nocka K, Beier DR, Chu T-Y, Buck J, Lahm H-W, Wellner D, Leder P, Besmer P. The hematopoietic growth factor KL is encoded by the SL locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell 1990; 63: 225-233.
22. McNiece IK, Langley KE, Zsebo KM. Recombinant human stem cell factor synergizes with GM-CSF, G-CSF, IL-3 and Epo to stimulate human progenitor cells in the myeloid and erythroid lineages. Exp Hematol 1991; 19: 226-231.
23. Broxmeyer HE, Cooper S, Lu L, Hangoc G, Anderson D, Cosman D, Lyman SD, Williams DE. Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells. Blood 1991; 77: 2142-2149.
24. Abkowitz JL, Sabo KM, Nakamoto B, Blau CA, Martin FH, Zsebo KM, Papayannopoulou T. Diamond-Blackfan anemia: in vitro response of erythroid progenitors to the ligand for c-kit. Blood 1991; 9: 2198-2202.
25. + hematopoietic progenitors in Diamond-Blackfan anemia. Blood 1991; 9: 2203-2210.
26. Olivieri NF, Grunberger T, Ben-David Y, Ng J, Williams DE, Lymann S, Anderson DM, Axelrad AA, Correa P, Bernstein A, Freedman MH. Diamond-Blackfan anemia: heterogenous response of hematopoietic progenitor cells in vitro to the protein product of the steel locus. Blood 1991; 9: 2211-2215.
27. Wodnar-Filipowicz A, Tichelli A, Zsebo KM, Speck B, Nissen C. Stem cell factor stimulates the in vitro growth of bone marrow cells from aplastic anemia patients. Blood 1992; 12: 3196-3202.
28. Backx B, Breeders L, Löwenberg B. Kit-ligand improves erythropoiesis in myelodysplastic syndrome. Blood 1992; 80: 1213-1217.
29. Piacibello W, Sanavio F, Bresso P, Severino A, Carlesso N, Pregno P, Stacchini A, Morelli S, Fubini L, Gallo E, Aglietta M, Ferrero D. Stem cell factor improvement of proliferation and maintenance of hemopoietic progenitors in myelodysplastic syndromes. Leukemia 1994; 8: 250-257.
30. Glinsmann-Gibson B, Spier C, Baier M, Taetle R, Broudy VC, List AF. Mast cell growth factor (c-kit ligand) restores growth of multipotent progenitors in myelodysplastic syndrome. Leukemia 1994; 5: 827-832.
31. Soligo D, Servida F, Cortelezzi A, Pedretti D, Uziel L, Morgutti M, Pogliani E, Lambertenghi Deliliers G. Effects of recombinant human stem cell factor (rh-SCF) on colony formation and long-term bone marrow cultures (LTBMC) in patients with myelodysplastic syndrome. Eur J Haematol 1994; 52: 53-60.
32. Backx B, Breeders L, Touw I, Löwenberg B. Blast colony-forming cells in myelodysplastic syndrome: decreased potential to generate erythroid precursors. Leukemia 1993; 7: 75-79.
33. Bot FJ, van Eijk L, Breeders L, Aarden LA, Löwenberg B. Interleukin-6 synergizes with M-CSF in the formation of macrophage colonies from purified human marrow progenitor cells. Blood 1989; 73: 435-437.
34. Perussia B, Trinchieri G, Lebman D, Jankiewicz J, Lange B, Rovera G. Monoclonal antibodies that detect differentiation surface antigens on human myelomonocytic cells. Blood 1982; 59: 382-392.
35. Van der Reijden HJ, Van Rhenen DJ, Lansdorp PM, Van't Veer MB, Langenhuijsen MMAC, Engelfriet CP, Von Dem Borne AEGKr. A comparison of surface marker analysis and FAB classification in acute myeloid leukemia. Blood 1983; 61: 443-448.
36. Bot FJ, Dorssers L, Wagemaker G, Lowenberg B. Stimulating spectrum of humana recombinant muiti-CSF (IL-3) on human marrow precursors: importance of accessory cells. Blood 1988; 71: 1609-1614.
37. Wognum AW, Lansdorp PM, Humphries RK, Krystal G. Detection and isolation of the erythropoietin receptor using biotinylated erythropoietin. Blood 1990; 76: 696-705.
38. Chomczynski P, Sacchi N. Single-step method for RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156-159.
39. Liboi E, Carroll M, D'Andrea A, Mathey-Prevot B. Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. Proc Natl Acad Sci USA 1993; 90: 11351-11355.
40. D'Andrea A, Yoshimura A, Youssouffian H, Zon L, Koo JW, Lodish HF. The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol 1991; 11: 1980-1987.
41. Quelle FW, Wojchowski DM. Localized cytosolic domains of the erythropoietin receptor regulate growth signalling and downmodulate responsiveness to granulocyte-macrophage colony-stimulating factor. Proc Natl Acad Sci USA 1991; 88: 4801-4805
42. de la Chapelle A, Träskelin A-L, Juvonen E. Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis. Proc Natl Acad Sci USA 1993; 90: 4495-4499.
43. Ward JC, Harris KW, Penny LA, Forget BG, Kitamura T, Winkelmann JC. A structurally abnormal erythropoietin receptor gene in a human erythroleukemia cell line. Exp Hematol 1992; 20: 371-373.
44. Dong F, Brynes RK, Tidow N, Weite K, Löwenberg B, Touw IP. Mutations truncating the C-terminal cytoplasmic region of G-CSF receptor in acute myeloid leukemia preceded by severe congenital neutropenia. New Engl J Med 1995; 333: 487-493.
45. Abkowitz JL, Broudy VC, Bennett LG, Zsebo KM, Martin FH. Absence of abnormalities of c-kit or its ligand in two patients with Diamond-Blackfan anemia. Blood 1992; 79: 25-28.
46. Bowen DT, Padua RA, Burnett AK, deCastro CM, Kaufman RE. Two new polymorphisms but no mutations of the KIT gene in patients with myelodysplasia at positions corresponding to human FMS and murine W locus mutational hot spots. Leukemia 1993; 7: 1883-1885.
47. Griftin JD, Löwenberg B. Clonogenic cells in acute myeloblastic leukemia. Blood 1986; 68. 1185-1195.