메뉴 건너뛰기




Volumn 102, Issue 2, 2010, Pages 301-315

Erythropoiesis-stimulating agents in oncology: A study-level meta-analysis of survival and other safety outcomes

Author keywords

Anaemia; Erythropoiesis stimulating agent; Meta analysis; Oncology

Indexed keywords

ANTIANEMIC AGENT;

EID: 75549086280     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605498     Document Type: Article
Times cited : (217)

References (109)
  • 1
    • 33845334505 scopus 로고    scopus 로고
    • Effect of treatment with epoetin beta on short-term tumour progression and survival in anaemic patients with cancer: A meta-analysis
    • Aapro M, Coiffier B, Dunst J, Osterborg A, Burger HU (2006) Effect of treatment with epoetin beta on short-term tumour progression and survival in anaemic patients with cancer: a meta-analysis. Br J Cancer 95: 1467-1473
    • (2006) Br J Cancer , vol.95 , pp. 1467-1473
    • Aapro, M.1    Coiffier, B.2    Dunst, J.3    Osterborg, A.4    Burger, H.U.5
  • 2
    • 39149121539 scopus 로고    scopus 로고
    • Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracycline-and/or taxane-based chemotherapy: Results of the Breast Cancer-Anemia and the Value of Erythropoietin (BRAVE) study
    • Aapro M, Leonard RC, Barnadas A, Marangolo M, Untch M, Malamos N, Mayordomo J, Reichert D, Pedrini JL, Ukarma L, Scherhag A, Burger HU (2008a) Effect of once-weekly epoetin beta on survival in patients with metastatic breast cancer receiving anthracycline-and/or taxane-based chemotherapy: results of the Breast Cancer-Anemia and the Value of Erythropoietin (BRAVE) study. J Clin Oncol 26: 592-598
    • (2008) J Clin Oncol , vol.26 , pp. 592-598
    • Aapro, M.1    Leonard, R.C.2    Barnadas, A.3    Marangolo, M.4    Untch, M.5    Malamos, N.6    Mayordomo, J.7    Reichert, D.8    Pedrini, J.L.9    Ukarma, L.10    Scherhag, A.11    Burger, H.U.12
  • 3
    • 42949174250 scopus 로고    scopus 로고
    • Effect of treatment with epoetin-beta on survival, tumour progression and thromboembolic events in patients with cancer: An updated meta-analysis of 12 randomised controlled studies including 2301 patients
    • Aapro M, Scherhag A, Burger HU (2008b) Effect of treatment with epoetin-beta on survival, tumour progression and thromboembolic events in patients with cancer: an updated meta-analysis of 12 randomised controlled studies including 2301 patients. Br J Cancer 99: 14-22
    • (2008) Br J Cancer , vol.99 , pp. 14-22
    • Aapro, M.1    Scherhag, A.2    Burger, H.U.3
  • 4
    • 0027220373 scopus 로고
    • Erythropoietin for anaemia in cancer patients
    • Abels R (1993) Erythropoietin for anaemia in cancer patients. Eur J Cancer 29A(Suppl 2): S2-S8
    • (1993) Eur J Cancer , vol.29 A , Issue.SUPPL. 2
    • Abels, R.1
  • 6
    • 33645502107 scopus 로고    scopus 로고
    • Perioperative blood transfusions for the recurrence of colorectal cancer
    • Amato A, Pescatori M (2006) Perioperative blood transfusions for the recurrence of colorectal cancer. Cochrane Database Syst Rev 25(1): CD005033
    • (2006) Cochrane Database Syst Rev , vol.25 , Issue.1
    • Amato, A.1    Pescatori, M.2
  • 7
    • 69849085700 scopus 로고    scopus 로고
    • Amgen (Amgen press release). Nov 30 [Accessed February 29, 2008]
    • s 'PREPARE' study in breast cancer patients (Amgen press release). Nov 30, 2007; Available from: http://wwwext.amgen.com/media/media-pr-detail.jsp? year 2007&releaseID 1083091 [Accessed February 29, 2008]
    • (2007) s 'Prepare' Study in Breast Cancer Patients
  • 9
    • 2142825053 scopus 로고    scopus 로고
    • Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: A multicenter, open-label, randomized trial
    • Auerbach M, Ballard H, Trout JR, McIlwain M, Ackerman A, Bahrain H, Balan S, Barker L, Rana J (2004) Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial. J Clin Oncol 22: 1301-1307
    • (2004) J Clin Oncol , vol.22 , pp. 1301-1307
    • Auerbach, M.1    Ballard, H.2    Trout, J.R.3    McIlwain, M.4    Ackerman, A.5    Bahrain, H.6    Balan, S.7    Barker, L.8    Rana, J.9
  • 10
    • 0037261477 scopus 로고    scopus 로고
    • Prevention of anemia in patients with solid tumors receiving platinum-based chemotherapy by recombinant human erythropoietin (rHuEpo): A prospective, open label, randomized trial by the Hellenic Cooperative Oncology Group
    • Bamias A, Aravantinos G, Kalofonos C, Timotheadou N, Siafaka V, Vlahou I, Janinis D, Pectasides D, Pavlidis N, Fountzilas G (2003) Prevention of anemia in patients with solid tumors receiving platinum-based chemotherapy by recombinant human erythropoietin (rHuEpo): a prospective, open label, randomized trial by the Hellenic Cooperative Oncology Group. Oncology 64: 102-110
    • (2003) Oncology , vol.64 , pp. 102-110
    • Bamias, A.1    Aravantinos, G.2    Kalofonos, C.3    Timotheadou, N.4    Siafaka, V.5    Vlahou, I.6    Janinis, D.7    Pectasides, D.8    Pavlidis, N.9    Fountzilas, G.10
  • 11
    • 9444293510 scopus 로고    scopus 로고
    • The rationale for pathogen-inactivation treatment of blood components
    • Barbara JA (2004) The rationale for pathogen-inactivation treatment of blood components. Int J Hematol 80: 311-316
    • (2004) Int J Hematol , vol.80 , pp. 311-316
    • Barbara, J.A.1
  • 13
    • 43249129663 scopus 로고    scopus 로고
    • Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia
    • Bastit L, Vandebroek A, Altintas S, Gaede B, Pinter T, Suto TS, Mossman TW, Smith KE, Vansteenkiste JF (2008) Randomized, multicenter, controlled trial comparing the efficacy and safety of darbepoetin alpha administered every 3 weeks with or without intravenous iron in patients with chemotherapy-induced anemia. J Clin Oncol 26: 1611-1618
    • (2008) J Clin Oncol , vol.26 , pp. 1611-1618
    • Bastit, L.1    Vandebroek, A.2    Altintas, S.3    Gaede, B.4    Pinter, T.5    Suto, T.S.6    Mossman, T.W.7    Smith, K.E.8    Vansteenkiste, J.F.9
  • 14
    • 58149265356 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents in the treatment of cancer-associated anemia-Reply
    • Bennett CL, Henke M, Lai SY (2008a) Erythropoiesis-stimulating agents in the treatment of cancer-associated anemia-Reply. JAMA 300: 2855-2857
    • (2008) JAMA , vol.300 , pp. 2855-2857
    • Bennett, C.L.1    Henke, M.2    Lai, S.Y.3
  • 16
    • 0032572913 scopus 로고    scopus 로고
    • The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin
    • Besarab A, Bolton WK, Browne JK, Egrie JC, Nissenson AR, Okamoto DM, Schwab SJ, Goodkin DA (1998) The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 339: 584-590
    • (1998) N Engl J Med , vol.339 , pp. 584-590
    • Besarab, A.1    Bolton, W.K.2    Browne, J.K.3    Egrie, J.C.4    Nissenson, A.R.5    Okamoto, D.M.6    Schwab, S.J.7    Goodkin, D.A.8
  • 17
    • 21444431924 scopus 로고    scopus 로고
    • Results with sequential adjuvant chemo-radiotherapy with vs without epoetin alfa for patients with high-risk cervical cancer: Results of a prospective, randomized, open and controlled AGO-and NOGGO-intergroup study
    • Abstract 477PD
    • Blohmer J-U, Wurschmidt F, Petry U, Weise G, Sehouli J, Kimming R, Dressler P, Kentenich H, Kohls A, Lichtenegger W (2004) Results with sequential adjuvant chemo-radiotherapy with vs without epoetin alfa for patients with high-risk cervical cancer: results of a prospective, randomized, open and controlled AGO-and NOGGO-intergroup study. Ann Oncol 15: Abstract 477PD
    • (2004) Ann Oncol , vol.15
    • Blohmer, J.-U.1    Wurschmidt, F.2    Petry, U.3    Weise, G.4    Sehouli, J.5    Kimming, R.6    Dressler, P.7    Kentenich, H.8    Kohls, A.9    Lichtenegger, W.10
  • 18
    • 58149242793 scopus 로고    scopus 로고
    • Erythropoiesis-stimulating agents in the treatment of cancer-associated anemia
    • author reply 2855-2857
    • Bohlius J, Engert A, Schwarzer G (2008) Erythropoiesis-stimulating agents in the treatment of cancer-associated anemia. JAMA 300: 2854-2855; author reply 2855-2857
    • (2008) JAMA , vol.300 , pp. 2854-2855
    • Bohlius, J.1    Engert, A.2    Schwarzer, G.3
  • 23
    • 32144463027 scopus 로고    scopus 로고
    • Epoetin beta (NeoRecormon) therapy in patients with solid tumours receiving platinum and non-platinum chemotherapy: A meta-analysis
    • Boogaerts M, Oberhoff C, Ten Bokkel Huinink W, Nowrousian MR, Hayward CR, Burger HU (2006) Epoetin beta (NeoRecormon) therapy in patients with solid tumours receiving platinum and non-platinum chemotherapy: a meta-analysis. Anticancer Res 26: 479-484
    • (2006) Anticancer Res , vol.26 , pp. 479-484
    • Boogaerts, M.1    Oberhoff, C.2    Ten Bokkel Huinink, W.3    Nowrousian, M.R.4    Hayward, C.R.5    Burger, H.U.6
  • 25
    • 0028295942 scopus 로고
    • Recombinant human erythropoietin treatment in cisplatin-associated anemia: A randomized, double-blind trial with placebo
    • Cascinu S, Fedeli A, Del Ferro E, Luzi Fedeli S, Catalano G (1994) Recombinant human erythropoietin treatment in cisplatin-associated anemia: a randomized, double-blind trial with placebo. J Clin Oncol 12: 1058-1062
    • (1994) J Clin Oncol , vol.12 , pp. 1058-1062
    • Cascinu, S.1    Fedeli, A.2    Del Ferro, E.3    Luzi Fedeli, S.4    Catalano, G.5
  • 28
    • 0038157066 scopus 로고    scopus 로고
    • Control of cancer-related anemia with erythropoietic agents: A review of evidence for improved quality of life and clinical outcomes
    • Cella D, Dobrez D, Glaspy J (2003) Control of cancer-related anemia with erythropoietic agents: a review of evidence for improved quality of life and clinical outcomes. Ann Oncol 14: 511-519
    • (2003) Ann Oncol , vol.14 , pp. 511-519
    • Cella, D.1    Dobrez, D.2    Glaspy, J.3
  • 29
    • 18444398661 scopus 로고    scopus 로고
    • Weekly epoetin alfa maintains hemoglobin, improves quality of life, and reduces transfusion in breast cancer patients receiving chemotherapy
    • Chang J, Couture F, Young S, McWatters KL, Lau CY (2005) Weekly epoetin alfa maintains hemoglobin, improves quality of life, and reduces transfusion in breast cancer patients receiving chemotherapy. J Clin Oncol 23: 2597-2605
    • (2005) J Clin Oncol , vol.23 , pp. 2597-2605
    • Chang, J.1    Couture, F.2    Young, S.3    McWatters, K.L.4    Lau, C.Y.5
  • 30
    • 34447115042 scopus 로고    scopus 로고
    • Efficacy and safety of every-2-week darbepoetin alfa in patients with anemia of cancer: A controlled, randomized, open-label phase II trial
    • Charu V, Belani CP, Gill AN, Bhatt M, Tomita D, Rossi G, Ben-Jacob A (2007) Efficacy and safety of every-2-week darbepoetin alfa in patients with anemia of cancer: a controlled, randomized, open-label phase II trial. Oncologist 12: 727-737
    • (2007) Oncologist , vol.12 , pp. 727-737
    • Charu, V.1    Belani, C.P.2    Gill, A.N.3    Bhatt, M.4    Tomita, D.5    Rossi, G.6    Ben-Jacob, A.7
  • 31
    • 17844401577 scopus 로고    scopus 로고
    • Impact of epopetin beta versus standard care on quality of life in patients with malignant disease
    • Paper presented at June 21-24, 2001 Frankfurt, Germany
    • Coiffier B, Boogaerts M, Kainz C, Group EBQW, Group EBPW (2001) Impact of epopetin beta versus standard care on quality of life in patients with malignant disease. Paper presented at: The 6th Annual Meeting of the European Haematology Association; June 21-24, 2001; Frankfurt, Germany
    • (2001) The 6th Annual Meeting of the European Haematology Association
    • Coiffier, B.1    Boogaerts, M.2    Kainz, C.3    Ebqw, G.4    Ebpw, G.5
  • 33
    • 0035021209 scopus 로고    scopus 로고
    • Efficacy of epoetin alfa in the treatment of anaemia of multiple myeloma
    • Dammacco F, Castoldi G, Rodjer S (2001) Efficacy of epoetin alfa in the treatment of anaemia of multiple myeloma. Br J Haematol 113: 172-179
    • (2001) Br J Haematol , vol.113 , pp. 172-179
    • Dammacco, F.1    Castoldi, G.2    Rodjer, S.3
  • 34
    • 75549088553 scopus 로고    scopus 로고
    • Epoetin alfa (EPO) and survival in patients with non-resectable NSCLC-Interim results
    • Presented at the Berlin 2006 [Accessed 29 May 2008]
    • Debus J, Hindermann S, Morr H, Mezger J, Sebastian M, Angermund R, Drings P (2006) Epoetin alfa (EPO) and survival in patients with non-resectable NSCLC-Interim results. Presented at the German Medical Sciences Meeting, Berlin 2006. Available from: http://www.egms.de/en/ meetings/dkk2006/06dkk257.shtml [Accessed 29 May 2008]
    • (2006) German Medical Sciences Meeting
    • Debus, J.1    Hindermann, S.2    Morr, H.3    Mezger, J.4    Sebastian, M.5    Angermund, R.6    Drings, P.7
  • 36
    • 0031785826 scopus 로고    scopus 로고
    • Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: Results from a prospective community oncology study. Procrit Study Group
    • Demetri GD, Kris M, Wade J, Degos L, Cella D (1998) Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: results from a prospective community oncology study. Procrit Study Group. J Clin Oncol 16: 3412-3425
    • (1998) J Clin Oncol , vol.16 , pp. 3412-3425
    • Demetri, G.D.1    Kris, M.2    Wade, J.3    Degos, L.4    Cella, D.5
  • 37
    • 0033214594 scopus 로고    scopus 로고
    • Erythropoietin reduces anemia and transfusions: A randomized trial with or without erythropoietin during chemotherapy
    • Dunphy FR, Harrison BR, Dunleavy TL, Rodriguez JJ, Hilton JG, Boyd JH (1999) Erythropoietin reduces anemia and transfusions: a randomized trial with or without erythropoietin during chemotherapy. Cancer 86: 1362-1367
    • (1999) Cancer , vol.86 , pp. 1362-1367
    • Dunphy, F.R.1    Harrison, B.R.2    Dunleavy, T.L.3    Rodriguez, J.J.4    Hilton, J.G.5    Boyd, J.H.6
  • 38
    • 0030720013 scopus 로고    scopus 로고
    • Meta-analysis: Principles and procedures
    • Egger M, Smith GD, Phillips AN (1997) Meta-analysis: principles and procedures. BMJ 315: 1533-1537
    • (1997) BMJ , vol.315 , pp. 1533-1537
    • Egger, M.1    Smith, G.D.2    Phillips, A.N.3
  • 40
    • 75549088651 scopus 로고    scopus 로고
    • eMC electronic Medicines Compendium (eMC) website [Accessed October 29, 2008]
    • eMC (2008) electronic Medicines Compendium (eMC) website. Available from: http://emc.medicines.org.uk [Accessed October 29, 2008]
    • (2008)
  • 42
    • 75549088260 scopus 로고    scopus 로고
    • Role of erythropoetin (EPO) in patients with Hodgkin lymphoma
    • On behalf of the German Hodgkin Study Group Paper presented at November 3-7 2007; Cologne, Germany
    • Engert A (2007) On behalf of the German Hodgkin Study Group. Role of erythropoetin (EPO) in patients with Hodgkin lymphoma. Paper presented at The 7th International Symposium on Hodgkin Lymphoma; November 3-7, 2007; Cologne, Germany
    • (2007) The 7th International Symposium on Hodgkin Lymphoma
    • Engert, A.1
  • 43
    • 31944444232 scopus 로고    scopus 로고
    • Erythropoietin stimulates growth and STAT5 phosphorylation in human prostate epithelial and prostate cancer cells
    • Feldman L, Wang Y, Rhim JS, Bhattacharya N, Loda M, Sytkowski AJ (2006) Erythropoietin stimulates growth and STAT5 phosphorylation in human prostate epithelial and prostate cancer cells. Prostate 66: 135-145
    • (2006) Prostate , vol.66 , pp. 135-145
    • Feldman, L.1    Wang, Y.2    Rhim, J.S.3    Bhattacharya, N.4    Loda, M.5    Sytkowski, A.J.6
  • 44
    • 0035366382 scopus 로고    scopus 로고
    • Clinical evaluation of once weekly dosing of epoetin alfa in chemotherapy patients: Improvements in hemoglobin and quality of life are similar to three-times weekly dosing
    • Gabrilove JL, Cleeland CS, Livingston RB, Sarokhan B, Winer E, Einhorn LH (2001) Clinical evaluation of once weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life are similar to three-times weekly dosing. J Clin Oncol 19: 2875-2882
    • (2001) J Clin Oncol , vol.19 , pp. 2875-2882
    • Gabrilove, J.L.1    Cleeland, C.S.2    Livingston, R.B.3    Sarokhan, B.4    Winer, E.5    Einhorn, L.H.6
  • 45
    • 4644288189 scopus 로고    scopus 로고
    • Prevention of venous thromboembolism: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Geerts WH, Pineo GF, Heit JA, Bergqvist D, Lassen MR, Colwell CW, Ray JG (2004) Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126: 338S-400S
    • (2004) Chest , vol.126
    • Geerts, W.H.1    Pineo, G.F.2    Heit, J.A.3    Bergqvist, D.4    Lassen, M.R.5    Colwell, C.W.6    Ray, J.G.7
  • 46
    • 0031044609 scopus 로고    scopus 로고
    • Impact of therapy with epoetin alfa on clinical outcomes in patients with non-myeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group
    • Glaspy J, Bukowski R, Steinberg D, Taylor C, Tchekmedyian S, Vadhan-Raj S (1997) Impact of therapy with epoetin alfa on clinical outcomes in patients with non-myeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group. J Clin Oncol 15: 1218-1234
    • (1997) J Clin Oncol , vol.15 , pp. 1218-1234
    • Glaspy, J.1    Bukowski, R.2    Steinberg, D.3    Taylor, C.4    Tchekmedyian, S.5    Vadhan-Raj, S.6
  • 47
    • 37849051917 scopus 로고    scopus 로고
    • Treating anemia of cancer with darbepoetin alfa administered every 4 weeks: Final results from a phase 2, randomized, double-blind, placebo-controlled study in cancer patients not receiving chemotherapy and/or radiotherapy
    • Abstract 1304
    • Gordon DH, Nichols G, Ben-Jacob A, Lam H, Lillie T, Miller C (2006) Treating anemia of cancer with darbepoetin alfa administered every 4 weeks: Final results from a phase 2, randomized, double-blind, placebo-controlled study in cancer patients not receiving chemotherapy and/or radiotherapy. Blood 108: Abstract 1304
    • (2006) Blood , vol.108
    • Gordon, D.H.1    Nichols, G.2    Ben-Jacob, A.3    Lam, H.4    Lillie, T.5    Miller, C.6
  • 48
    • 33847293031 scopus 로고    scopus 로고
    • Impact of maintaining Hb with epoetin alfa on time to progression (TTP), overall survival (OS), quality of life (QOL), and transfusion reduction in limited disease SCLC patients
    • Abstract O-154
    • Goss G, Feld R, Bezjak A, Perry G, Melosky B, Smith C, Snee M, Plante R, Lau C (2005) Impact of maintaining Hb with epoetin alfa on time to progression (TTP), overall survival (OS), quality of life (QOL), and transfusion reduction in limited disease SCLC patients. Lung Cancer 49: S53, Abstract O-154
    • (2005) Lung Cancer , vol.49
    • Goss, G.1    Feld, R.2    Bezjak, A.3    Perry, G.4    Melosky, B.5    Smith, C.6    Snee, M.7    Plante, R.8    Lau, C.9
  • 49
    • 0033530262 scopus 로고    scopus 로고
    • Chemotherapy-induced anemia in adults: Incidence and treatment
    • Groopman JE, Itri LM (1999) Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst 91: 1616-1634
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1616-1634
    • Groopman, J.E.1    Itri, L.M.2
  • 50
    • 33644825219 scopus 로고    scopus 로고
    • Efficacy and safety analysis of epoetin alfa in patients with small-cell lung cancer: A randomized, double-blind, placebo-controlled trial
    • Grote T, Yeilding AL, Castillo R, Butler D, Fishkin E, Henry DH, DeLeo M, Fink K, Sullivan DJ (2005) Efficacy and safety analysis of epoetin alfa in patients with small-cell lung cancer: a randomized, double-blind, placebo-controlled trial. J Clin Oncol 23: 9377-9386
    • (2005) J Clin Oncol , vol.23 , pp. 9377-9386
    • Grote, T.1    Yeilding, A.L.2    Castillo, R.3    Butler, D.4    Fishkin, E.5    Henry, D.H.6    Deleo, M.7    Fink, K.8    Sullivan, D.J.9
  • 53
    • 27244443556 scopus 로고    scopus 로고
    • Darbepoetin alfa for the treatment of chemotherapy-induced anemia: Disease progression and survival analysis from four randomized, double-blind, placebo-controlled trials
    • Hedenus M, Vansteenkiste J, Kotasek D, Austin M, Amado RG (2005) Darbepoetin alfa for the treatment of chemotherapy-induced anemia: disease progression and survival analysis from four randomized, double-blind, placebo-controlled trials. J Clin Oncol 23: 6941-6948
    • (2005) J Clin Oncol , vol.23 , pp. 6941-6948
    • Hedenus, M.1    Vansteenkiste, J.2    Kotasek, D.3    Austin, M.4    Amado, R.G.5
  • 57
    • 1842577545 scopus 로고    scopus 로고
    • Prevalence and outcomes of anemia in cancer: A systematic review of the literature
    • Knight K, Wade S, Balducci L (2004) Prevalence and outcomes of anemia in cancer: a systematic review of the literature. Am J Med 116(Suppl 7A): 11S-26S
    • (2004) Am J Med , vol.116 , Issue.SUPPL. 7A
    • Knight, K.1    Wade, S.2    Balducci, L.3
  • 58
    • 0142026183 scopus 로고    scopus 로고
    • Darbepoetin alfa administered every 3 weeks alleviates anaemia in patients with solid tumours receiving chemotherapy; Results of a double-blind, placebo-controlled, randomised study
    • Kotasek D, Steger G, Faught W, Underhill C, Poulsen E, Colowick AB, Rossi G, Mackey J (2003) Darbepoetin alfa administered every 3 weeks alleviates anaemia in patients with solid tumours receiving chemotherapy; results of a double-blind, placebo-controlled, randomised study. Eur J Cancer 39: 2026-2034
    • (2003) Eur J Cancer , vol.39 , pp. 2026-2034
    • Kotasek, D.1    Steger, G.2    Faught, W.3    Underhill, C.4    Poulsen, E.5    Colowick, A.B.6    Rossi, G.7    MacKey, J.8
  • 59
    • 0031172237 scopus 로고    scopus 로고
    • Erythropoietin treatment under polychemotherapy in patients with gynecologic malignancies: A prospective, randomized, double-blind placebo-controlled multicenter study
    • Kurz C, Marth C, Windbichler G, Lahousen M, Medl M, Vavra N, Sevelda P (1997) Erythropoietin treatment under polychemotherapy in patients with gynecologic malignancies: a prospective, randomized, double-blind placebo-controlled multicenter study. Gynecol Oncol 65: 461-466
    • (1997) Gynecol Oncol , vol.65 , pp. 461-466
    • Kurz, C.1    Marth, C.2    Windbichler, G.3    Lahousen, M.4    Medl, M.5    Vavra, N.6    Sevelda, P.7
  • 60
    • 21744451644 scopus 로고    scopus 로고
    • Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma
    • Lai SY, Childs EE, Xi S, Coppelli FM, Gooding WE, Wells A, Ferris RL, Grandis JR (2005) Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene 24: 4442-4449
    • (2005) Oncogene , vol.24 , pp. 4442-4449
    • Lai, S.Y.1    Childs, E.E.2    Xi, S.3    Coppelli, F.M.4    Gooding, W.E.5    Wells, A.6    Ferris, R.L.7    Grandis, J.R.8
  • 61
  • 62
    • 0036622936 scopus 로고    scopus 로고
    • Cancer and thromboembolic disease: Pathogenic mechanisms
    • Lee AY (2002) Cancer and thromboembolic disease: pathogenic mechanisms. Cancer Treat Rev 28: 137-140
    • (2002) Cancer Treat Rev , vol.28 , pp. 137-140
    • Lee, A.Y.1
  • 64
    • 0035367087 scopus 로고    scopus 로고
    • Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: Results of a randomized, double-blind, placebo-controlled trial
    • Littlewood TJ, Bajetta E, Nortier JW, Vercammen E, Rapoport B (2001) Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: results of a randomized, double-blind, placebo-controlled trial. J Clin Oncol 19: 2865-2874
    • (2001) J Clin Oncol , vol.19 , pp. 2865-2874
    • Littlewood, T.J.1    Bajetta, E.2    Nortier, J.W.3    Vercammen, E.4    Rapoport, B.5
  • 65
    • 3242694357 scopus 로고    scopus 로고
    • Transfusion-related acute lung injury: A review
    • Looney MR, Gropper MA, Matthay MA (2004) Transfusion-related acute lung injury: a review. Chest 126: 249-258
    • (2004) Chest , vol.126 , pp. 249-258
    • Looney, M.R.1    Gropper, M.A.2    Matthay, M.A.3
  • 70
    • 40549087788 scopus 로고    scopus 로고
    • The impact of epoetin-alpha on anemia, red blood cell (RBC) transfusions, and survival in breast cancer patients (pts) treated with dose-dense sequential chemotherapy: Mature results of an AGO phase III study (ETC trial)
    • Abstract 569
    • Moebus V, Lueck H, Thomssen C, Harbeck N, Nitz U, Kreienberg R, Jackisch C, Schneeweiss A, Huober J, du Bois A, Untch M (2007) The impact of epoetin-alpha on anemia, red blood cell (RBC) transfusions, and survival in breast cancer patients (pts) treated with dose-dense sequential chemotherapy: Mature results of an AGO phase III study (ETC trial). J Clin Oncol 25: Abstract 569
    • (2007) J Clin Oncol , vol.25
    • Moebus, V.1    Lueck, H.2    Thomssen, C.3    Harbeck, N.4    Nitz, U.5    Kreienberg, R.6    Jackisch, C.7    Schneeweiss, A.8    Huober, J.9    Du Bois, A.10    Untch, M.11
  • 71
    • 23344434516 scopus 로고    scopus 로고
    • Evaluation of epoetin supplemented with oral iron in patients with solid malignancies and chronic anemia not receiving anticancer treatment
    • Mystakidou K, Kalaidopoulou O, Katsouda E, Parpa E, Kouskouni E, Chondros C, Tsiatas ML, Vlahos L (2005) Evaluation of epoetin supplemented with oral iron in patients with solid malignancies and chronic anemia not receiving anticancer treatment. Anticancer Res 25: 3495-3500
    • (2005) Anticancer Res , vol.25 , pp. 3495-3500
    • Mystakidou, K.1    Kalaidopoulou, O.2    Katsouda, E.3    Parpa, E.4    Kouskouni, E.5    Chondros, C.6    Tsiatas, M.L.7    Vlahos, L.8
  • 72
    • 18744401355 scopus 로고    scopus 로고
    • Feasibility of quantifying the effects of epoetin alfa therapy on cognitive function in women with breast cancer undergoing adjuvant or neoadjuvant chemotherapy
    • O'Shaughnessy JA, Vukelja SJ, Holmes FA, Savin M, Jones M, Royall D, George M, Von Hoff D (2005) Feasibility of quantifying the effects of epoetin alfa therapy on cognitive function in women with breast cancer undergoing adjuvant or neoadjuvant chemotherapy. Clin Breast Cancer 5: 439-446
    • (2005) Clin Breast Cancer , vol.5 , pp. 439-446
    • O'Shaughnessy, J.A.1    Vukelja, S.J.2    Holmes, F.A.3    Savin, M.4    Jones, M.5    Royall, D.6    George, M.7    Von Hoff, D.8
  • 74
    • 75549085209 scopus 로고    scopus 로고
    • ODAC Amgen Inc. in collaboration with Johnson & Johnson Pharmaceutical Research and Development, L.L.C.Background Information. For 13 March 2008 [Accessed March 21, 2008]
    • ODAC (2008) Amgen Inc. in collaboration with Johnson & Johnson Pharmaceutical Research and Development, L.L.C.Background Information. For The Oncologic Drugs Advisory Comittee (ODAC) Meeting 13 March 2008. Available from: http://www.fda.gov/ohrms/dockets/ac/08/ briefing/2008-4345b2-00-FDA-index.htm [Accessed March 21, 2008]
    • (2008) The Oncologic Drugs Advisory Comittee (ODAC) Meeting
  • 75
    • 70349854649 scopus 로고    scopus 로고
    • Ortho Centocor Ortho Biotech Inc.: L.P. Raritan, NJ
    • s (Epoetin alfa) Package Insert. Centocor Ortho Biotech Inc.: L.P., Raritan, NJ
    • (2009) s (Epoetin Alfa) Package Insert
  • 76
    • 33846615414 scopus 로고    scopus 로고
    • Preclinical studies of erythropoietin receptor expression in tumour cells: Impact on clinical use of erythropoietic proteins to correct cancer-related anaemia
    • Osterborg A, Aapro M, Cornes P, Haselbeck A, Hayward CR, Jelkmann W (2007) Preclinical studies of erythropoietin receptor expression in tumour cells: impact on clinical use of erythropoietic proteins to correct cancer-related anaemia. Eur J Cancer 43: 510-519
    • (2007) Eur J Cancer , vol.43 , pp. 510-519
    • Osterborg, A.1    Aapro, M.2    Cornes, P.3    Haselbeck, A.4    Hayward, C.R.5    Jelkmann, W.6
  • 77
    • 0030012115 scopus 로고    scopus 로고
    • Recombinant human erythropoietin in transfusion-dependent anemic patients with multiple myeloma and non-Hodgkin's lymphoma-a randomized multicenter study. the European Study Group of Erythropoietin (Epoetin Beta) Treatment in Multiple Myeloma and Non-Hodgkin's Lymphoma
    • Osterborg A, Boogaerts MA, Cimino R, Essers U, Holowiecki J, Juliusson G, Jager G, Najman A, Peest D (1996) Recombinant human erythropoietin in transfusion-dependent anemic patients with multiple myeloma and non-Hodgkin's lymphoma-a randomized multicenter study. The European Study Group of Erythropoietin (Epoetin Beta) Treatment in Multiple Myeloma and Non-Hodgkin's Lymphoma. Blood 87: 2675-2682
    • (1996) Blood , vol.87 , pp. 2675-2682
    • Osterborg, A.1    Boogaerts, M.A.2    Cimino, R.3    Essers, U.4    Holowiecki, J.5    Juliusson, G.6    Jager, G.7    Najman, A.8    Peest, D.9
  • 78
    • 17644390912 scopus 로고    scopus 로고
    • Impact of epoetin-beta on survival of patients with lymphoproliferative malignancies: Long-term follow up of a large randomized study
    • Osterborg A, Brandberg Y, Hedenus M (2005) Impact of epoetin-beta on survival of patients with lymphoproliferative malignancies: long-term follow up of a large randomized study. Br J Haematol 129: 206-209
    • (2005) Br J Haematol , vol.129 , pp. 206-209
    • Osterborg, A.1    Brandberg, Y.2    Hedenus, M.3
  • 80
    • 0028915908 scopus 로고
    • Effective treatment of disease-related anaemia in B-chronic lymphocytic leukaemia patients with recombinant human erythropoietin
    • Pangalis GA, Poziopoulos C, Angelopoulou MK, Siakantaris MP, Panayiotidis P (1995) Effective treatment of disease-related anaemia in B-chronic lymphocytic leukaemia patients with recombinant human erythropoietin. Br J Haematol 89: 627-629
    • (1995) Br J Haematol , vol.89 , pp. 627-629
    • Pangalis, G.A.1    Poziopoulos, C.2    Angelopoulou, M.K.3    Siakantaris, M.P.4    Panayiotidis, P.5
  • 81
    • 44249111891 scopus 로고    scopus 로고
    • Safety and efficacy of darbepoetin alfa in previously untreated extensive-stage small-cell lung cancer treated with platinum plus etoposide
    • Pirker R, Ramlau RA, Schuette W, Zatloukal P, Ferreira I, Lillie T, Vansteenkiste JF (2008) Safety and efficacy of darbepoetin alfa in previously untreated extensive-stage small-cell lung cancer treated with platinum plus etoposide. J Clin Oncol 26: 2342-2349
    • (2008) J Clin Oncol , vol.26 , pp. 2342-2349
    • Pirker, R.1    Ramlau, R.A.2    Schuette, W.3    Zatloukal, P.4    Ferreira, I.5    Lillie, T.6    Vansteenkiste, J.F.7
  • 82
    • 5344280697 scopus 로고    scopus 로고
    • Early intervention with epoetin alfa in breast cancer (BC) patients (pts) undergoing chemotherapy (CT): Results of a randomized, multicenter, phase IIIb study (EPO-INT-47 Study Group)
    • Pronzato P, Cortesi E, van der Rijt C, Moreno-Nogueira A, Raimundo D, Ostler P, Bols A, Rosso R (2002) Early intervention with epoetin alfa in breast cancer (BC) patients (pts) undergoing chemotherapy (CT): results of a randomized, multicenter, phase IIIb study (EPO-INT-47 Study Group). Ann Oncol 13: 168
    • (2002) Ann Oncol , vol.13 , pp. 168
    • Pronzato, P.1    Cortesi, E.2    Van Der Rijt, C.3    Moreno-Nogueira, A.4    Raimundo, D.5    Ostler, P.6    Bols, A.7    Rosso, R.8
  • 83
    • 33747031725 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled study of quality of life, hematologic end points, and safety of weekly epoetin alfa in children with cancer receiving myelosuppressive chemotherapy
    • Razzouk BI, Hord JD, Hockenberry M, Hinds PS, Feusner J, Williams D, Rackoff WR (2006) Double-blind, placebo-controlled study of quality of life, hematologic end points, and safety of weekly epoetin alfa in children with cancer receiving myelosuppressive chemotherapy. J Clin Oncol 24: 3583-3589
    • (2006) J Clin Oncol , vol.24 , pp. 3583-3589
    • Razzouk, B.I.1    Hord, J.D.2    Hockenberry, M.3    Hinds, P.S.4    Feusner, J.5    Williams, D.6    Rackoff, W.R.7
  • 84
    • 0000258522 scopus 로고
    • Clinical and health status assessments in anemic chronic lymphocytic leukemia (CLL patients treated with epoetin alfa (EPO)
    • Abstract 2091
    • Rose E, Rai K, Revicki D, Brown R, Reblando J (1994) Clinical and health status assessments in anemic chronic lymphocytic leukemia (CLL) patients treated with epoetin alfa (EPO). Blood 84: 526a (Abstract 2091)
    • (1994) Blood , vol.84
    • Rose, E.1    Rai, K.2    Revicki, D.3    Brown, R.4    Reblando, J.5
  • 85
    • 33745936043 scopus 로고    scopus 로고
    • Clinical benefits and risks associated with epoetin and darbepoetin in patients with chemotherapy-induced anemia: A systematic review of the literature
    • Ross SD, Allen IE, Henry DH, Seaman C, Sercus B, Goodnough LT (2006) Clinical benefits and risks associated with epoetin and darbepoetin in patients with chemotherapy-induced anemia: a systematic review of the literature. Clin Ther 28: 801-831
    • (2006) Clin Ther , vol.28 , pp. 801-831
    • Ross, S.D.1    Allen, I.E.2    Henry, D.H.3    Seaman, C.4    Sercus, B.5    Goodnough, L.T.6
  • 86
    • 22144472209 scopus 로고    scopus 로고
    • Effects of early intervention with epoetin alfa on transfusion requirement, hemoglobin level and survival during platinum-based chemotherapy: Results of a multicenter randomised controlled trial
    • Savonije JH, van Groeningen CJ, van Bochove A, Honkoop AH, van Felius CL, Wormhoudt LW, Giaccone G (2005) Effects of early intervention with epoetin alfa on transfusion requirement, hemoglobin level and survival during platinum-based chemotherapy: results of a multicenter randomised controlled trial. Eur J Cancer 41: 1560-1569
    • (2005) Eur J Cancer , vol.41 , pp. 1560-1569
    • Savonije, J.H.1    Van Groeningen, C.J.2    Van Bochove, A.3    Honkoop, A.H.4    Van Felius, C.L.5    Wormhoudt, L.W.6    Giaccone, G.7
  • 87
    • 33846687689 scopus 로고    scopus 로고
    • Anemia in patients with cancer: Incidence, causes, impact, management, and use of treatment guidelines and protocols
    • Schwartz RN (2007) Anemia in patients with cancer: incidence, causes, impact, management, and use of treatment guidelines and protocols. Am J Health Syst Pharm 64: S5-13
    • (2007) Am J Health Syst Pharm , vol.64
    • Schwartz, R.N.1
  • 90
    • 34547120946 scopus 로고    scopus 로고
    • Expression and function of erythropoietin receptors in tumors: Implications for the use of erythropoiesis-stimulating agents in cancer patients
    • Sinclair AM, Todd MD, Forsythe K, Knox SJ, Elliott S, Begley CG (2007) Expression and function of erythropoietin receptors in tumors: implications for the use of erythropoiesis-stimulating agents in cancer patients. Cancer 110: 477-488
    • (2007) Cancer , vol.110 , pp. 477-488
    • Sinclair, A.M.1    Todd, M.D.2    Forsythe, K.3    Knox, S.J.4    Elliott, S.5    Begley, C.G.6
  • 92
    • 41949140285 scopus 로고    scopus 로고
    • Darbepoetin alfa for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: Results of a phase III, multicenter, randomized, double-blind, placebo-controlled study
    • Smith Jr RE., Aapro MS, Ludwig H, Pinter T, Smakal M, Ciuleanu TE, Chen L, Lillie T, Glaspy JA (2008) Darbepoetin alfa for the treatment of anemia in patients with active cancer not receiving chemotherapy or radiotherapy: results of a phase III, multicenter, randomized, double-blind, placebo-controlled study. J Clin Oncol 26: 1040-1050
    • (2008) J Clin Oncol , vol.26 , pp. 1040-1050
    • Smith Jr, R.E.1    Aapro, M.S.2    Ludwig, H.3    Pinter, T.4    Smakal, M.5    Ciuleanu, T.E.6    Chen, L.7    Lillie, T.8    Glaspy, J.A.9
  • 94
    • 34547888014 scopus 로고    scopus 로고
    • Medical and economic impact of anemia in hospitalized patients
    • Spence RK (2007) Medical and economic impact of anemia in hospitalized patients. Am J Health Syst Pharm 64: S3-10
    • (2007) Am J Health Syst Pharm , vol.64
    • Spence, R.K.1
  • 96
    • 0033982421 scopus 로고    scopus 로고
    • Quantitative expression of erythropoietin receptor (EPO-R) on acute leukaemia cells: Relationships between the amount of EPO-R and CD phenotypes, in vitro proliferative response, the amount of other cytokine receptors and clinical prognosis. Japan Adult Leukaemia Study Group
    • Takeshita A, Shinjo K, Higuchi M, Miyawaki S, Takemoto Y, Kishimoto Y, Saito K, Takuchi H, Kuriyama K, Kimura Y, Asou N, Takahashi M, Hotta T, Kanamaru A, Ueda R, Ohno R (2000) Quantitative expression of erythropoietin receptor (EPO-R) on acute leukaemia cells: relationships between the amount of EPO-R and CD phenotypes, in vitro proliferative response, the amount of other cytokine receptors and clinical prognosis. Japan Adult Leukaemia Study Group. Br J Haematol 108: 55-63
    • (2000) Br J Haematol , vol.108 , pp. 55-63
    • Takeshita, A.1    Shinjo, K.2    Higuchi, M.3    Miyawaki, S.4    Takemoto, Y.5    Kishimoto, Y.6    Saito, K.7    Takuchi, H.8    Kuriyama, K.9    Kimura, Y.10    Asou, N.11    Takahashi, M.12    Hotta, T.13    Kanamaru, A.14    Ueda, R.15    Ohno, R.16
  • 97
    • 33846358098 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled study of darbepoetin alfa every 3 weeks for the treatment of chemotherapy-induced anemia
    • Abstract 3556
    • Taylor K, Ganly P, Charu V, DiBenedetto J, Kracht K, Rossi G, Hernandez E (2005) Randomized, double-blind, placebo-controlled study of darbepoetin alfa every 3 weeks for the treatment of chemotherapy-induced anemia. Blood 106: Abstract 3556
    • (2005) Blood , vol.106
    • Taylor, K.1    Ganly, P.2    Charu, V.3    Dibenedetto, J.4    Kracht, K.5    Rossi, G.6    Hernandez, E.7
  • 100
    • 38649128164 scopus 로고    scopus 로고
    • Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dl with erythropoietin vs above 10.0 g/dl without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer
    • Thomas G, Ali S, Hoebers FJ, Darcy KM, Rodgers WH, Patel M, Abulafia O, Lucci III JA, Begg AC (2008) Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dl with erythropoietin vs above 10.0 g/dl without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer. Gynecol Oncol 108: 317-325
    • (2008) Gynecol Oncol , vol.108 , pp. 317-325
    • Thomas, G.1    Ali, S.2    Hoebers, F.J.3    Darcy, K.M.4    Rodgers, W.H.5    Patel, M.6    Abulafia, O.7    Lucci Iii, J.A.8    Begg, A.C.9
  • 101
    • 0034651839 scopus 로고    scopus 로고
    • Effect of recombinant human erythropoietin combined with granulocyte/macrophage colony-stimulating factor in the treatment of patients with myelodysplastic syndrome
    • GM/EPO MDS Study Group
    • Thompson JA, Gilliland DG, Prchal JT, Bennett JM, Larholt K, Nelson RA, Rose EH, Dugan MH (2000) Effect of recombinant human erythropoietin combined with granulocyte/macrophage colony-stimulating factor in the treatment of patients with myelodysplastic syndrome. GM/EPO MDS Study Group. Blood 95: 1175-1179
    • (2000) Blood , vol.95 , pp. 1175-1179
    • Thompson, J.A.1    Gilliland, D.G.2    Prchal, J.T.3    Bennett, J.M.4    Larholt, K.5    Nelson, R.A.6    Rose, E.H.7    Dugan, M.H.8
  • 102
    • 0003298925 scopus 로고    scopus 로고
    • Erythropoietin decreases transfusion requirements during radiotherapy
    • Abstract 1558
    • Throuvalas N, Antonadou D, Boufi M, Lavey R, Malamos N (2000) Erythropoietin decreases transfusion requirements during radiotherapy. J Clin Oncol 19: Abstract 1558
    • (2000) J Clin Oncol , vol.19
    • Throuvalas, N.1    Antonadou, D.2    Boufi, M.3    Lavey, R.4    Malamos, N.5
  • 104
    • 28444469283 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of epoetin alfa (Procrit in patients with rectal and gastric cancer undergoing chemo-radiotherapy (CT/RT) followed by surgery: Early termination of the trial due to increased incidence of thrombo-embolic events (TEE)
    • Abstract 2915
    • Vadhan-Raj S, Skibber JM, Crane C, Bueso-Ramos CE, Rodriguez-Bigas MA, Feig BW, Lin EH, Ajani JA, Collard M, Johnson MM, Hamilton SR, JanJan N (2004) Randomized, double-blind, placebo-controlled trial of epoetin alfa (Procrit) in patients with rectal and gastric cancer undergoing chemo-radiotherapy (CT/RT) followed by surgery: early termination of the trial due to increased incidence of thrombo-embolic events (TEE). Blood 104: Abstract 2915
    • (2004) Blood , vol.104
    • Vadhan-Raj, S.1    Skibber, J.M.2    Crane, C.3    Bueso-Ramos, C.E.4    Rodriguez-Bigas, M.A.5    Feig, B.W.6    Lin, E.H.7    Ajani, J.A.8    Collard, M.9    Johnson, M.M.10    Hamilton, S.R.11    Janjan, N.12
  • 106
    • 0033852337 scopus 로고    scopus 로고
    • Erythropoietin stimulates proliferation of human renal carcinoma cells
    • Westenfelder C, Baranowski RL (2000) Erythropoietin stimulates proliferation of human renal carcinoma cells. Kidney Int 58: 647-657
    • (2000) Kidney Int , vol.58 , pp. 647-657
    • Westenfelder, C.1    Baranowski, R.L.2
  • 107
    • 33645750210 scopus 로고    scopus 로고
    • Epoetin alfa in platinum-treated ovarian cancer patients: Results of a multinational, multicentre, randomised trial
    • Wilkinson PM, Antonopoulos M, Lahousen M, Lind M, Kosmidis P (2006) Epoetin alfa in platinum-treated ovarian cancer patients: results of a multinational, multicentre, randomised trial. Br J Cancer 94: 947-954
    • (2006) Br J Cancer , vol.94 , pp. 947-954
    • Wilkinson, P.M.1    Antonopoulos, M.2    Lahousen, M.3    Lind, M.4    Kosmidis, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.