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Volumn 100, Issue 10, 2009, Pages 1589-1602

Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-B-dependent activation of the urokinase plasminogen activator system

Author keywords

Extracellular matrix; Lipopolysaccharide; Perioperative metastatic tumour growth; Urokinase plasminogen activator system

Indexed keywords

AMILORIDE; BACTERIUM LIPOPOLYSACCHARIDE; ENZYME ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR; RECEPTOR ANTIBODY; SN 50; TOLL LIKE RECEPTOR 4; UROKINASE; UROKINASE RECEPTOR; VITRONECTIN;

EID: 66149129910     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604942     Document Type: Article
Times cited : (99)

References (44)
  • 1
    • 4544342570 scopus 로고    scopus 로고
    • Nuclear factor-κB: The enemy within
    • Aggarwal B (2004) Nuclear factor-κB: the enemy within. Cancer Cell 6: 203-208
    • (2004) Cancer Cell , vol.6 , pp. 203-208
    • Aggarwal, B.1
  • 2
    • 0033972059 scopus 로고    scopus 로고
    • Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: A new model for metastasis
    • Al-Mehdi AB, Tozawa K, Fisher AB, Shientag L, Lee A, Muschel RJ (2000) Intravascular origin of metastasis from the proliferation of endothelium-attached tumor cells: a new model for metastasis. Nat Med 1: 100-110
    • (2000) Nat Med , vol.1 , pp. 100-110
    • Al-Mehdi, A.B.1    Tozawa, K.2    Fisher, A.B.3    Shientag, L.4    Lee, A.5    Muschel, R.J.6
  • 3
    • 0035746418 scopus 로고    scopus 로고
    • Tumor cell adhesion to endothelial cells is increased by endotoxin via an upregulation of beta-1 integrin expression
    • Andrews EJ, Wang JH, Winter DC, Lang WE, Redmond HP (2001) Tumor cell adhesion to endothelial cells is increased by endotoxin via an upregulation of beta-1 integrin expression. J Surg Res 97: 14-19
    • (2001) J Surg Res , vol.97 , pp. 14-19
    • Andrews, E.J.1    Wang, J.H.2    Winter, D.C.3    Lang, W.E.4    Redmond, H.P.5
  • 4
    • 0038804192 scopus 로고    scopus 로고
    • Responsiveness of intestinal epithelial cell lines to lipopolysaccharide is correlated with Toll-like receptor 4 but not Toll-like receptor 2 or CD14 expression
    • Böcker U, Yezerskyy O, Feick P, Manigold T, Panja A, Kalina U, Herweck F, Rossol S, Singer MV (2003) Responsiveness of intestinal epithelial cell lines to lipopolysaccharide is correlated with Toll-like receptor 4 but not Toll-like receptor 2 or CD14 expression. Int J Colorectal Dis 18: 25-32
    • (2003) Int J Colorectal Dis , vol.18 , pp. 25-32
    • Böcker, U.1    Yezerskyy, O.2    Feick, P.3    Manigold, T.4    Panja, A.5    Kalina, U.6    Herweck, F.7    Rossol, S.8    Singer, M.V.9
  • 5
    • 31844432409 scopus 로고    scopus 로고
    • The targeting of phosphoinositide-3 kinase attenuates pulmonary metastatic tumor growth following laparotomy
    • Coffey JC, Wang JH, Bouchier-Hayes D, Cotter TG, Redmond HP (2006) The targeting of phosphoinositide-3 kinase attenuates pulmonary metastatic tumor growth following laparotomy. Ann Surg 243(2): 250-256
    • (2006) Ann Surg , vol.243 , Issue.2 , pp. 250-256
    • Coffey, J.C.1    Wang, J.H.2    Bouchier-Hayes, D.3    Cotter, T.G.4    Redmond, H.P.5
  • 6
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420: 860-866
    • (2002) Nature , vol.420 , pp. 860-866
    • Coussens, L.M.1    Werb, Z.2
  • 7
    • 0025273735 scopus 로고
    • Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1
    • Cubellis MV, Wun TC, Blasi F (1990) Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 9: 1079-1085
    • (1990) EMBO J , vol.9 , pp. 1079-1085
    • Cubellis, M.V.1    Wun, T.C.2    Blasi, F.3
  • 8
    • 0031709279 scopus 로고    scopus 로고
    • The effect of laparotomy and laparoscopy on the establishment of spontaneous tumour metastases
    • Da Costa ML, Redmond HP, Boucher-Hayes DJ (1998) The effect of laparotomy and laparoscopy on the establishment of spontaneous tumour metastases. Surgery 124: 516-526
    • (1998) Surgery , vol.124 , pp. 516-526
    • Da Costa, M.L.1    Redmond, H.P.2    Boucher-Hayes, D.J.3
  • 9
    • 0023685082 scopus 로고
    • Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin)
    • Declerck PJ, De Mol M, Alessi MC, Baudner S, Paques EP, Preissner KT, Muller Berghaus G, Collen D (1988) Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin). J Biol Chem 263: 15454-15461
    • (1988) J Biol Chem , vol.263 , pp. 15454-15461
    • Declerck, P.J.1    De Mol, M.2    Alessi, M.C.3    Baudner, S.4    Paques, E.P.5    Preissner, K.T.6    Muller Berghaus, G.7    Collen, D.8
  • 10
    • 0035848682 scopus 로고    scopus 로고
    • Urokinase/ urokinase receptor and vitronectin/alpha (v)-beta (3) integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways
    • Degryse B, Orlando S, Resnati M, Rabbani SA, Blasi F (2001) Urokinase/ urokinase receptor and vitronectin/alpha (v)-beta (3) integrin induce chemotaxis and cytoskeleton reorganization through different signaling pathways. Oncogene 20: 2032-2043
    • (2001) Oncogene , vol.20 , pp. 2032-2043
    • Degryse, B.1    Orlando, S.2    Resnati, M.3    Rabbani, S.A.4    Blasi, F.5
  • 11
    • 0036329424 scopus 로고    scopus 로고
    • Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: From pilot to level 1 evidence studies
    • Duffy MJ (2002) Urokinase plasminogen activator and its inhibitor, PAI-1, as prognostic markers in breast cancer: from pilot to level 1 evidence studies. Clin Chem 48: 1194-1197
    • (2002) Clin Chem , vol.48 , pp. 1194-1197
    • Duffy, M.J.1
  • 12
    • 0031983177 scopus 로고    scopus 로고
    • The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells
    • Dumler I, Weis A, Mayboroda OA, Maasch C, Jerke U, Haller H, Gulba DC (1998) The Jak/Stat pathway and urokinase receptor signaling in human aortic vascular smooth muscle cells. J Biol Chem 273: 315-321
    • (1998) J Biol Chem , vol.273 , pp. 315-321
    • Dumler, I.1    Weis, A.2    Mayboroda, O.A.3    Maasch, C.4    Jerke, U.5    Haller, H.6    Gulba, D.C.7
  • 13
    • 0001037808 scopus 로고
    • Cycloheximide: Aspects of inhibition of protein synthesis in mammalian cells
    • Ennis HL, Lubin M (1964) Cycloheximide: aspects of inhibition of protein synthesis in mammalian cells. Science 146: 1474-1476
    • (1964) Science , vol.146 , pp. 1474-1476
    • Ennis, H.L.1    Lubin, M.2
  • 14
    • 2942591963 scopus 로고    scopus 로고
    • Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system
    • Ertongur S, Lang S, Mack B, Wosikowski K, Muehlenweg B, Gires O (2004) Inhibition of the invasion capacity of carcinoma cells by WX-UK1, a novel synthetic inhibitor of the urokinase-type plasminogen activator system. Int J Cancer 110: 815-824
    • (2004) Int J Cancer , vol.110 , pp. 815-824
    • Ertongur, S.1    Lang, S.2    Mack, B.3    Wosikowski, K.4    Muehlenweg, B.5    Gires, O.6
  • 18
    • 0037057521 scopus 로고    scopus 로고
    • Lipopolysaccharide induced metastatic growth is associated with increased angiogenesis, vascular permenability and tumour cell invasion
    • Harmey JH, Bucana CD, Lui W, Byrne AM, McDonnell S, Lynch C, Bouchar-Hayes D, Dong Z (2002) Lipopolysaccharide induced metastatic growth is associated with increased angiogenesis, vascular permenability and tumour cell invasion. Int J Cancer 101: 415-422
    • (2002) Int J Cancer , vol.101 , pp. 415-422
    • Harmey, J.H.1    Bucana, C.D.2    Lui, W.3    Byrne, A.M.4    McDonnell, S.5    Lynch, C.6    Bouchar-Hayes, D.7    Dong, Z.8
  • 19
    • 0026716204 scopus 로고
    • Biology of tumor metastasis
    • Hart IR, Saini A (1992) Biology of tumor metastasis. Lancet 339: 1453-1457
    • (1992) Lancet , vol.339 , pp. 1453-1457
    • Hart, I.R.1    Saini, A.2
  • 20
    • 0032833646 scopus 로고    scopus 로고
    • Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization
    • Harvey SR, Sait SN, Xu Y, Bailey JL, Penetrante RM, Markus G (1999) Demonstration of urokinase expression in cancer cells of colon adenocarcinomas by immunohistochemistry and in situ hybridization. Am J Pathol 155: 1115-1120
    • (1999) Am J Pathol , vol.155 , pp. 1115-1120
    • Harvey, S.R.1    Sait, S.N.2    Xu, Y.3    Bailey, J.L.4    Penetrante, R.M.5    Markus, G.6
  • 21
  • 22
    • 0029873910 scopus 로고    scopus 로고
    • The urokinase receptor is a major vitronectin-binding protein on endothelial cells
    • Kanse SM, Kost C, Wilhelm OG, Andreasen PA, Preissner KT (1996) The urokinase receptor is a major vitronectin-binding protein on endothelial cells. Exp Cell Res 224: 344-353
    • (1996) Exp Cell Res , vol.224 , pp. 344-353
    • Kanse, S.M.1    Kost, C.2    Wilhelm, O.G.3    Andreasen, P.A.4    Preissner, K.T.5
  • 23
    • 0034773518 scopus 로고    scopus 로고
    • The influence of tumour resection on angiostatin levels and tumour growth - an experimental study on tumour bearing mice
    • Li TS, Kaneda Y, Ueda K (2001) The influence of tumour resection on angiostatin levels and tumour growth - an experimental study on tumour bearing mice. Eur J Cancer 37: 2283-2288
    • (2001) Eur J Cancer , vol.37 , pp. 2283-2288
    • Li, T.S.1    Kaneda, Y.2    Ueda, K.3
  • 24
    • 4544224979 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNF-alpha to TRAIL-mediated tumor regression
    • Luo JL, Maeda S, Hsu LC, Yagita H, Karin M (2004) Inhibition of NF-kappaB in cancer cells converts inflammation-induced tumor growth mediated by TNF-alpha to TRAIL-mediated tumor regression. Cancer Cell 6: 297-305
    • (2004) Cancer Cell , vol.6 , pp. 297-305
    • Luo, J.L.1    Maeda, S.2    Hsu, L.C.3    Yagita, H.4    Karin, M.5
  • 25
    • 0026670898 scopus 로고
    • Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosphorylation in murine macrophages
    • Manthey CL, Brandes ME, Perera PY, Vogel SN (1992) Taxol increases steady-state levels of lipopolysaccharide-inducible genes and protein-tyrosine phosphorylation in murine macrophages. J Immunol 149(7): 2459-2465
    • (1992) J Immunol , vol.149 , Issue.7 , pp. 2459-2465
    • Manthey, C.L.1    Brandes, M.E.2    Perera, P.Y.3    Vogel, S.N.4
  • 26
    • 13744251436 scopus 로고    scopus 로고
    • Systemic therapy for colorectal cancer
    • Meyerhardt JA, Mayer RJ (2005) Systemic therapy for colorectal cancer. N Engl J Med 352: 476-487
    • (2005) N Engl J Med , vol.352 , pp. 476-487
    • Meyerhardt, J.A.1    Mayer, R.J.2
  • 27
    • 0032478829 scopus 로고    scopus 로고
    • Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility
    • Nguyen DH, Hussaini IM, Gonias SL (1998) Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility. J Biol Chem 273: 8502-8507
    • (1998) J Biol Chem , vol.273 , pp. 8502-8507
    • Nguyen, D.H.1    Hussaini, I.M.2    Gonias, S.L.3
  • 28
    • 0035173628 scopus 로고    scopus 로고
    • CD11b/CD18 acts in concert with CD14 and Tolllike receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression
    • Perera PY, Mayadas TN, Takeuchi O, Akira S, Zaks-Zilberman M, Goyert SM, Vogel SN (2001) CD11b/CD18 acts in concert with CD14 and Tolllike receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression. J Immunol 166: 574-579
    • (2001) J Immunol , vol.166 , pp. 574-579
    • Perera, P.Y.1    Mayadas, T.N.2    Takeuchi, O.3    Akira, S.4    Zaks-Zilberman, M.5    Goyert, S.M.6    Vogel, S.N.7
  • 29
    • 0032713893 scopus 로고    scopus 로고
    • The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease
    • Pidgeon GP, Harmey JH, Kay E, Da Costa M, Redmond HP, Bouchier-Hayes DJ (1999) The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease. Br J Cancer 81: 1311-1317
    • (1999) Br J Cancer , vol.81 , pp. 1311-1317
    • Pidgeon, G.P.1    Harmey, J.H.2    Kay, E.3    Da Costa, M.4    Redmond, H.P.5    Bouchier-Hayes, D.J.6
  • 30
    • 0024195895 scopus 로고
    • Proteolytic mechanisms operating at the surface of invasive cells
    • Pollanen J, Stephens R, Salonen EM, Vaheri A (1988) Proteolytic mechanisms operating at the surface of invasive cells. Adv Exp Med Biol 233: 187-199
    • (1988) Adv Exp Med Biol , vol.233 , pp. 187-199
    • Pollanen, J.1    Stephens, R.2    Salonen, E.M.3    Vaheri, A.4
  • 31
    • 0025234559 scopus 로고
    • Prourokinase activation on the surface of human rhabdomyosarcoma cells: Localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class-2 plasmino-gen activator inhibitor
    • Pollanen J, Vaheri A, Tapiovaara H, Riley E, Bertram K, Woodrow G, Stephens RW (1990) Prourokinase activation on the surface of human rhabdomyosarcoma cells: localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class-2 plasmino-gen activator inhibitor. Proc Natl Acad Sci USA 87: 2230-2234
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2230-2234
    • Pollanen, J.1    Vaheri, A.2    Tapiovaara, H.3    Riley, E.4    Bertram, K.5    Woodrow, G.6    Stephens, R.W.7
  • 32
    • 0025052018 scopus 로고
    • Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis
    • Roldan AL, Cubellis MV, Masucci MT, Behrendt N, Lund LR, Danø K, Appella E, Blasi F (1990) Cloning and expression of the receptor for human urokinase plasminogen activator, a central molecule in cell surface, plasmin dependent proteolysis. EMBO J 9: 467-474
    • (1990) EMBO J , vol.9 , pp. 467-474
    • Roldan, A.L.1    Cubellis, M.V.2    Masucci, M.T.3    Behrendt, N.4    Lund, L.R.5    Danø, K.6    Appella, E.7    Blasi, F.8
  • 35
    • 0038364216 scopus 로고    scopus 로고
    • The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy
    • Sidenius N, Blasi F (2003) The urokinase plasminogen activator system in cancer: recent advances and implication for prognosis and therapy. Cancer Metastasis Rev 22: 205-222
    • (2003) Cancer Metastasis Rev , vol.22 , pp. 205-222
    • Sidenius, N.1    Blasi, F.2
  • 39
    • 0032540943 scopus 로고    scopus 로고
    • The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells
    • Tang H, Kerins DM, Hao Q, Inagami T, Vaughan DE (1998) The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells. J Biol Chem 273: 18268-18272
    • (1998) J Biol Chem , vol.273 , pp. 18268-18272
    • Tang, H.1    Kerins, D.M.2    Hao, Q.3    Inagami, T.4    Vaughan, D.E.5
  • 40
    • 0021984227 scopus 로고
    • A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase
    • Vassalli JD, Baccino D, Belin D (1985) A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase. J Cell Biol 100: 86-92
    • (1985) J Cell Biol , vol.100 , pp. 86-92
    • Vassalli, J.D.1    Baccino, D.2    Belin, D.3
  • 41
    • 0028334672 scopus 로고
    • Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy
    • Waltz DA, Chapman HA (1994) Reversible cellular adhesion to vitronectin linked to urokinase receptor occupancy. J Biol Chem 269: 14746-14750
    • (1994) J Biol Chem , vol.269 , pp. 14746-14750
    • Waltz, D.A.1    Chapman, H.A.2
  • 42
    • 0037438340 scopus 로고    scopus 로고
    • Endotoxin/lipopolysaccharide activates NF-kappaB and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism
    • Wang JH, Manning BJ, Wu QD, Blankson S, Bouchier-Hayes D, Redmond HP (2003) Endotoxin/lipopolysaccharide activates NF-kappaB and enhances tumor cell adhesion and invasion through a beta 1 integrin-dependent mechanism. J Immunol 170: 795-804
    • (2003) J Immunol , vol.170 , pp. 795-804
    • Wang, J.H.1    Manning, B.J.2    Wu, Q.D.3    Blankson, S.4    Bouchier-Hayes, D.5    Redmond, H.P.6
  • 44
    • 0030916129 scopus 로고    scopus 로고
    • Urokinase type plasminogen activator receptors associate with beta1 and beta3 integrins of fibrosarcoma cells: Dependence on extracellular matrix components
    • Xue W, Mizukami I, Todd III RF, Petty HR (1997) Urokinase type plasminogen activator receptors associate with beta1 and beta3 integrins of fibrosarcoma cells: dependence on extracellular matrix components. Cancer Res 57: 1682-1689
    • (1997) Cancer Res , vol.57 , pp. 1682-1689
    • Xue, W.1    Mizukami, I.2    Todd III, R.F.3    Petty, H.R.4


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