Inactivation of erythropoietin leads to defects in cardiac morphogenesis

Development

Volumn 126, Issue 16, 1999, Pages 3597-3605

  Wu, Hong ^a   Lee, Sang Hoon ^a,b   Gao, Jing ^a   Liu, Xin ^a   Iruela Arispe, M Luisa ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endocardium; Endothelial cells; Heart; Mouse; Myocardium

Indexed keywords

ERYTHROPOIETIN; ERYTHROPOIETIN RECEPTOR; GROWTH FACTOR; HEART RECEPTOR; MITOGENIC AGENT;

ANEMIA; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; ERYTHROID PRECURSOR CELL; HEART DEVELOPMENT; HEART FAILURE; HEART MUSCLE CELL; HYPOPLASIA; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CHIMERA; ERYTHROPOIETIN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HEART DEFECTS, CONGENITAL; MICE; MICE, KNOCKOUT; MORPHOGENESIS; MYOCARDIUM; RECEPTORS, ERYTHROPOIETIN; STEM CELLS;

ANIMALIA; MAMMALIA; MURINAE;

EID: 0032824560     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Albelda, S. M., Muller, W. A., Buck, C. A. and Newman, P. J. (1991). Molecular and cellular properties of PECAM-1 endoCAM/CD31: a novel vascular cell-cell adhesion molecule. J. Cell Biol. 114, 1059-1068.
2. Anagnostou, A., Lee, E. S. Kessimian, N. Levinson, R. and Steiner, M. (1990). Erythropoietin has a mitogenic and positive chemotactic effect on endothelial cells. Proc. Nat. Acad. Sci. USA 87, 5978-5982.
3. Anagnostou, A., Liu, Z. Steiner, M. Chin, K. Lee, E. S. Kessimian, N. and Noguchi. C. T. (1994). Erythropoietin receptor mRNA expression in human endothelial cells. Proc. Nat. Acad. Sci. USA 91, 3974-3978.
4. Besmer, P. (1991). The kit ligand encoded at the murine Steel locus: a pleiotropic growth and differentiation factor. Curr. Opin. Cell Biol. 3, 939-946.
5. Bradley, A. (1987). Production and analysis of chimaeric mice. In Teratocarcinomas and Embryonic Stem Cells (ed. E. J. Robertson), pp. 113-151. IRL Press, Washington, DC.
6. Broudy, V. C., Lin, N. L. and Kaushansky, K. (1995). Thrombopoietin c-mpl ligand acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro. Blood 85, 1719-1726.
7. Chen, J., Kubalak, S. W. and Chien, K. R. (1998). Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis. Development 125, 1943-1949.
8. Clouthier, D. E., Hosoda, K., Richardson, J. A., Williams, S. C., Yanagisawa, H., Kuwaki, T., Kumada, M., Hammer, R. E. and Yanagisawa, M. (1998). Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development 125, 813-824.
9. D'Andrea, A. D., Lodish, H. F. and Wong, G. G. (1989). Expression cloning of the murine erythropoietin receptor. Cell 57, 277-285.
10. Digicaylioglu, M., Bichet, S., Marti, H. H., Wenger, R. H., Rivas, L. A., Bauer, C. and Gassmann, M. (1995). Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proc. Nat. Acad. Sci. USA 92, 3717-3720.
11. -/- mice. Proc. Nat. Acad. Sci. USA 92, 7386-90.
12. Friedrich, G. and Soriano, P. (1991). Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 5, 1513-1523.
13. Gassmann, M., Casagranda, F. Orioli, D. Simon, H. Lai, C. Klein, R. and Lemke, G. (1995). Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor [see comments]. Nature 378, 390-394.
14. Gown, A. M., Jiang, J. J., Matles, H., Skelly, M., Goodpaster, T., Cass, L., Reshatof, M., Spaulding, D. and Coltrera. M. D. (1996). Validation of the S-phase specificity of histone H3 in situ hybridization in normal and malignant cells. J. Histochem. Cytochem. 44, 221-226.
15. Hirota, H., Chen, J., Betz, U. A. K., Rajewsky, K., Gu, Y., Ross, J., Müller, W. and Chien. K. R. (1999). Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress. Cell 97, 189-198.
16. Iruela-Arispe, M. L. and Sage, E. H. (1993). Endothelial cells exhibiting angiogenesis in vitro proliferate in response to TGF-beta 1. J. Cel. Biochem. 52, 414-430.
17. Ishibashi, T., Koziol, J. A. and Burstein, S. A. (1987). Human recombinant erythropoietin promotes differentiation of murine megakaryocytes in vitro. J. Clin. Invest. 79, 286-289.
18. Iyer, N. V., Kotch, L. E., Agani, F., Leung, S. W., Laughner, E., Wenger, R. H., Gassmann, M., Gearhart, J. D., Lawler, A. M., Yu, A. Y. and Semenza, G. L. (1998). Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev. 12, 149-162.
19. Kastner, P., Messaddeq, N., Mark, M., Wendling, O., Grondona, J. M., Ward, S., Ghyselinck, N. and Chambon, P. (1997). Vitamin A deficiency and mutations of RXRalpha, RXRbeta and RARalpha lead to early differentiation of embryonic ventricular cardiomyocytes. Development 124, 4749-4758.
20. Kieran, M. W., Perkins, A. C., Orkin, S. H. and Zon, L. I. (1996). Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor. Proc. Nat. Acad. Sci. USA 93, 9126-31.
21. Krantz, S. B. (1991). Erythropoietin. Blood 77, 419-434.
22. Kwee, L., Baldwin, H. S., Shen, H. M., Stewart, C. L., Buck, C., Buck, C. A. and Labow, M. A. (1995). Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule VCAM-1 deficient mice. Development 121, 489-503.
23. Lee, S. H., Hungerford, J. E., Little, C. D. and Iruela-Arispe, M. L. (1997). Proliferation and differentiation of smooth muscle cell precursors occurs simultaneously during the development of the vessel wall. Dev. Dynam. 209, 342-352.
24. Lin, C. S., Lim, S. K., D'Agati, V. and Costantini, F. (1996). Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev, 10, 154-164.
25. Liu, C., Shen, K., Liu, Z. and Noguchi, C. T. (1997). Regulated human erythropoietin receptor expression in mouse brain. J. Biol. Chem. 272, 32395-32400.
26. Liu, Z. Y., Chin, K. and Noguchi, C. T. (1994). Tissue specific expression of human erythropoietin receptor in transgenic mice. Dev. Biol. 166, 159-169.
27. Meyer, D. and Birchmeier, C. (1995). Multiple essential functions of neuregulin in development [see comments] [published erratum appears in Nature 1995 Dec 14;378 6558:753]. Nature 378, 386-390.
28. Morishita, E., Narita, H., Nishida, M., Kawashima, N., Yamagishi, K., Masuda, S., Nagao, M., Hatta, H. and Sasaki, R. (1996). Anti-erythropoietin receptor monoclonal antibody: epitope mapping, quantification of the soluble receptor, and detection of the solubilized transmembrane receptor and the receptor-expressing cells. Blood 88, 465-471.
29. Mucenski, M. L., McLain, K., Kier, A. B., Swerdlow, S. H., Schreiner, C. M., Miller, T. A., Pietryga, D. W., Scott, Jr., W. J. and Potter, S. S. (1991). A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 65, 677-689.
30. Neubauer, H., Cumano, A., Meuller, M., Wu, H., Huffstadt, U. and Pfeffer, K. (1998). Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 93, 397-409.
31. Papayannopoulou, T., Brice, M., Farrer, D. and Kaushansky, K. (1996). Insights into the cellular mechanisms of erythropoietin-thrombopoietin synergy. Exp. Hematol. 24, 660-669.
32. Ribatti, D., Presta, M., Vacca, A., Ria, R., Giuliani, R., Dell'Era, P., Nico, B., Roncali, L. and Dammacco, F. (1999). Human erythropoietin induces a pro-angiogenic phenotype in cultured endohtelial cells and stimulates neovascularization in vitro. Blood 93, 2627-2636.
33. Robertson, E. J. (1987). Teratocarcinomas and Embryonic Stem Cells. A Practical Approach.
34. Rugh, R. (1990). The Mouse: Its Reproduction and Development. Oxford University Press, Oxford: New York.
35. Ruzicka, D. L. and Schwartz, R. J. (1988). Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation. J. Cell Biol. 107, 2575-2586.
36. Tojo, A., Doumoto, M., Oka, K., Numabe, A., Kimura, K. and Yagi, S. (1996). Endothelin-mediated effect of erythropoietin on blood pressure and renal hemodynamics in hypertensive rats. Am. J. Physiol. 270, R744-7448.
37. Tran, C. M. and Sucov, H. M. (1998). The RXRalpha gene functions in a non-cell-autonomous manner during mouse cardiac morphogenesis. Development 125, 1951-1956.
38. Witthuhn, B. A., Quelle, F. W., Silvennoinen, O., Yi, T., Tang, B., Miura, O. and Ihle, J. N. (1993). JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin. Cell 74, 227-236.
39. Wu, H., Liu, X., Jaenisch, R. and Lodish, H. F. (1995). Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 83, 59-67.
40. Yang, J. T., Rayburn, H. and Hynes, R. O. (1995). Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development 121, 549-560.
41. Zeller, R., Bloch, K. D., Williams, B. S., Arceci, R. J. and Seidman, C. E. (1987). Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis. Genes Dev. 1, 693-698.