Conformational selection in trypsin-like proteases

Current Opinion in Structural Biology

Volumn 22, Issue 4, 2012, Pages 421-431

  Pozzi, Nicola ^a   Vogt, Austin D ^a   Gohara, David W ^a   Di Cera, Enrico ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; ANTICOAGULANT AGENT; LOW MOLECULAR WEIGHT HEPARIN; TRYPSIN; TRYPTASE;

AMINO TERMINAL SEQUENCE; ANTICOAGULATION; CATALYSIS; CONFORMATIONAL SELECTION; CONFORMATIONAL TRANSITION; DISSOCIATION CONSTANT; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; EQUILIBRIUM CONSTANT; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; REVIEW; SITE DIRECTED MUTAGENESIS; THROMBOSIS;

ALGORITHMS; ALLOSTERIC REGULATION; ANIMALS; CATALYTIC DOMAIN; HUMANS; KINETICS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN ENGINEERING; SERINE ENDOPEPTIDASES;

EID: 84865284711     PISSN: 0959440X     EISSN: 1879033X     Source Type: Journal    
DOI: 10.1016/j.sbi.2012.05.006     Document Type: Review

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