Allosteric peptide activators of pro-hepatocyte growth factor stimulate Met signaling

Journal of Biological Chemistry

Volumn 285, Issue 51, 2010, Pages 40362-40372

  Landgraf, Kyle E ^a   Santell, Lydia ^a   Billeci, Karen L ^a   Quan, Clifford ^a   Young, Judy C ^a   Maun, Henry R ^a   Kirchhofer, Daniel ^a   Lazarus, Robert A ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AKT PHOSPHORYLATION; ALLOSTERIC ACTIVATION; ALLOSTERIC ACTIVATOR; ALLOSTERIC REGULATION; CELL MIGRATION; CELL SURVIVAL; HEPATOCYTE GROWTH FACTOR; HETERODIMERS; HOT SPOT; IN-VITRO; INTERFEROMETRY DATA; N-TERMINALS; PEPTIDE BONDS; PROTEOLYTIC CLEAVAGE; PROTEOLYTIC PROCESSING; SERINE PROTEASE; TARGET RECEPTOR; TRYPSIN-LIKE SERINE PROTEASE;

AMINO ACIDS; CYTOLOGY; ENZYME ACTIVITY; PHOSPHORYLATION; SIGNALING;

PEPTIDES;

ARGININE; ENZYME ACTIVATOR; ENZYME PRECURSOR; GLYCINE; HETERODIMER; POLYPEPTIDE; PRO HEPATOCYTE GROWTH FACTOR; PROTEIN; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; SERINE PROTEINASE; UNCLASSIFIED DRUG; VALINE;

ALLOSTERISM; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA CHAIN; BINDING AFFINITY; CELL MIGRATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERFEROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; ANIMALS; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; HEPATOCYTE GROWTH FACTOR; HUMANS; MUTATION, MISSENSE; OLIGOPEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PRECURSORS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MET; RECEPTORS, GROWTH FACTOR; SERINE PROTEASES; SIGNAL TRANSDUCTION;

EID: 78650060373     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.179721     Document Type: Article

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