The factor VII zymogen structure reveals reregistration of β strands during activation

Structure

Volumn 9, Issue 7, 2001, Pages 627-636

  Eigenbrot, Charles ^a   Kirchhofer, Daniel ^a   Dennis, Mark S ^a   Santell, Lydia ^a   Lazarus, Robert A ^a   Stamos, Jennifer ^a   Ultsch, Mark H ^a  

^a GENENTECH INC   (United States)

Author keywords

Activation; Allostery; Factor VII; Tissue factor; X ray crystallography; Zymogen

Indexed keywords

BLOOD CLOTTING FACTOR 7; ENZYME PRECURSOR; EPIDERMAL GROWTH FACTOR DERIVATIVE; GLUTAMIC ACID; PROTEINASE; THROMBOPLASTIN; TRYPSIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CRYSTALLIZATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; STRUCTURE ANALYSIS;

ASPARTIC ACID; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME PRECURSORS; FACTOR VII; GLUTAMIC ACID; ISOLEUCINE; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; THROMBOPLASTIN;

EID: 0034941729     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00624-4     Document Type: Article

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