Evolution of enzyme cascades from embryonic development to blood coagulation

Trends in Biochemical Sciences

Volumn 27, Issue 2, 2002, Pages 67-74

  Krem, Maxwell M ^a   Cera, Enrico Di ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR; SERINE PROTEINASE;

AMINO ACID SEQUENCE; BLOOD CLOTTING; DROSOPHILA; EMBRYO DEVELOPMENT; ENZYME SUBSTRATE; EVOLUTION; IMMUNITY; INVERTEBRATE; MACROMOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SEQUENCE ANALYSIS; VERTEBRATE;

ANIMALS; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; DROSOPHILA PROTEINS; ENZYMES; EVOLUTION; PHYLOGENY; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; VERTEBRATES;

INVERTEBRATA; VERTEBRATA;

EID: 0036470428     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)02007-2     Document Type: Review

References (48)

1. Evolutionary families of peptidases
2. Autoproteolysis and feedback in a protease cascade directing Drosophila dorsal-ventral cell fate
3. Activation of a protease cascade involved in patterning the Drosophila embryo
4. Molecular markers of serine protease evolution
5. The C-terminal sequence encodes function in serine proteases
6. Sequence determinants of function and evolution in serine proteases
7. A common domain within the proenzyme regions of the Drosophila Snake and Easter proteins and Tachypleus proclotting enzyme defines a new subfamily of serine proteases
8. The ancestral complement system in sea urchins
9. Evolution of the complement system
10. The insect immune protein scolexin is a novel serine proteinase homolog
11. Reconstructing the evolution of vertebrate blood coagulation from a consideration of the amino acid sequences of clotting proteins
12. Serine proteases as mediators of mosquito immune responses
13. Constitutive activation of Toll-mediated antifungal defenses in serpin-deficient Drosophila
14. Phylogenetic perspectives in innate immunity
15. The dorsoventral regulatory gene cassette Spätzle/Toll/Cactus controls the potent antifungal response in Drosophila adults
16. Prothrombin messenger-RNA is expressed by cells of the central nervous system
17. Molecular-cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
18. Protease-activated receptor 3 is a second thrombin receptor in humans
19. Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities
20. Signaling pathways involved in thrombin-induced cell protection
21. Plasticity-related serine proteases in the brain
22. Thrombin, a survival factor for cultured myoblasts
23. Thrombin-induced chemotaxis and aggregation of neutrophils
24. Monocyte chemotaxis: Stimulation by specific exosite region in thrombin
25. Inhibition of thrombin-induced neuronal cell death by recombinant thrombomodulin and E5510, a synthetic thrombin receptor signaling inhibitor
26. Prothrombin promotes the invasiveness of melanoma cells by a different mechanism from thrombin
27. A synthetic inhibitor of factor Xa, DX-9065a, reduces proliferation of vascular smooth muscle cells in vivo in rats
28. Xa receptor EPR-1
29. A family of proteins related to Spätzle, the Toll receptor ligand, are encoded in the Drosophila genome
30. Toll-related receptors and the control of antimicrobial peptide expression in Drosophila
31. Crystal structure of Coagulogen, the clotting protein from horseshoe crab: A structural homologue of nerve growth factor
32. Proteolytic processing of the Drosophila Spaetzle protein by Easter generates a dimeric NGF-like molecule with ventralizing activity
33. Getting knotted: A model for the structure and activation of Spätzle
34. Limulus α2-macroglobulin: First evidence in an invertebrate for a protein containing an internal thiol ester bond
35. α2-Macroglobulin does not function as a C3 homologue in the plasma hemolytic system of the American horseshoe crab Limulus
36. Conserved role of a complement-like protein in phagocytosis revealed by dsRNA knockout in cultured cells of the mosquito, Anopheles gambiae
37. A family of fibrinogen-related proteins that precipitates parasite-derived molecules is produced by an invertebrate after infection
38. The clip-domain family of serine proteases in arthropods
39. Proclotting enzyme from horseshoe crab hemocytes: cDNA cloning, disulfide locations, and subcellular localization
40. New types of clotting factors and defense molecules found in horseshoe crab hemolymph: Their structures and functions
41. Structure and functions of the interaction domains of C1r and C1s: Keystones of the architecture of the C1 complex
42. Evolution of blood coagulation and fibrinolysis
43. Contributions of Gla and EGF-like domains to the function of vitamin K-dependent coagulation factors
44. Hydrophobic contact between the two epidermal growth factor-like domains of blood coagulation factor IX contributes to enzymatic activity
45. Kringles: Modules specialized for protein binding: Homology of the gelatin-binding region of fibronectin with the kringle structures of proteases
46. How low can Toll go?
47. A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans
48. The coagulation cascade: Initiation, maintenance, and regulation