Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Nature

Volumn 425, Issue 6957, 2003, Pages 535-539

  Friedrich, Rainer ^a   Panizzi, Peter ^b   Fuentes Prior, Pablo ^a   Richter, Klaus ^c   Verhamme, Ingrid ^b   Anderson, Patricia J ^b   Kawabata, Shun Ichiro ^d   Huber, Robert ^a   Bode, Wolfram ^a   Bock, Paul E ^b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BLOOD; COAGULATION; PATHOLOGY;

PATHOGENS;

ENZYMES;

COAGULASE; ENZYME PRECURSOR; ISOLEUCINE; PLASMINOGEN ACTIVATOR; PRETHROMBIN 2; PROTHROMBIN; STAPHYLOCOCCAL SERINE PROTEINASE; STREPTOKINASE; THROMBIN; UNCLASSIFIED DRUG; VALINE;

BIOLOGY; PATHOGEN;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN SECRETION; PROTEIN STRUCTURE; STAPHYLOCOCCUS AUREUS;

BINDING SITES; COAGULASE; COENZYMES; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTHROMBIN; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS;

EID: 0141929350     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01962     Document Type: Article

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