The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

Nature

Volumn 380, Issue 6569, 1996, Pages 41-46

  Banner, David W ^a   D'Arcy, Allan ^a   Chène, Christiane ^a   Winkler, Fritz K ^a   Guha, Arabinda ^b   Konigsberg, William H ^c   Nemerson, Yale ^b   Kirchhofer, Daniel ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7A; BLOOD CLOTTING FACTOR 9; THROMBOPLASTIN;

ARTICLE; BLOOD CLOTTING; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; PRIORITY JOURNAL; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; FACTOR IX; FACTOR VIIA; FACTOR X; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUBTILISINS; THROMBOPLASTIN;

EID: 0029926396     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/380041a0     Document Type: Article

References (51)

1. Kirchhofer, D. et al Proteins 22, 419-425 (1995).
2. Nemerson, Y. Blood 71, 1-8 (1988).
3. Davie, E. W. Thromb. Haemostasis 74, 1-6 (1995).
4. Rapaport, S. I. & Rao, L. V. M. Thromb. Haemostasis 74, 7-17 (1995).
5. Wilcox, J. N., Smith, K. M., Schwartz, S. M. & Gordon, D. Proc. natn. Acad. Sci. U.S.A. 86, 2839-2843 (1989)
6. Harlos, K. et al. Nature 370, 662-666 (1994).
7. Muller, Y. A., Ultsch, M. H , Kelley, R F. & de Vos, A. M. Biochemistry 33, 10864-10870 (1994).
8. Ruf, W., Schullek, J R., Stone, M. J. & Edgington, T S. Biochemistry 33, 1565-1572 (1994).
9. Ruf, W. et al. Biochemistry 34, 6310-6315 (1995).
10. Schullek, J R , Ruf, W. & Edgington, T. S. J. biol. Chem. 269, 19399-19403 (1994).
11. Gibbs, C S., McCurdy, S. N., Leung, L. L K. & Paborsky, L R. Biochemistry 33, 14003-14010 (1994)
12. Kelley, R. F., Costas, K. E , O'Connell, M P & Lazarus, R. A Biochemistry 34, 10383-10392 (1995)
13. O'Brien, D P et al. Biochemistry 33, 14162-14169 (1994).
14. Martin, D. M. A , Boys, C. W. G. & Ruf, W. FASEB J. 9, 852-859 (1995).
15. Bode, W., Mayr, I , Baumann, U., Huber, R., Stone, S. R. & Hofsteenge, J. EMBO J. 8, 3467-3475 (1989).
16. Banner, D. W. & Hadváry, P J. biol. Chem. 266, 20085-20093 (1991).
17. Soriano-Garcia, M., Padmanabhan K., de Vos, A. M. & Tulinsky, A. Biochemistry 31, 2554-2566 (1992)
18. Graves, B. J et al Nature 367, 532-538 (1994).
19. Selander-Sunnerhagen, M. et al. J. biol.Chem. 267, 19642-19649 (1992).
20. Toomey, J. R , Smith, K. J & Stafford, D. W. J. biol. Chem. 266, 19198-19202 (1991)
21. Clarke, B J et al. FEBS Lett. 298, 206-210 (1992).
22. Sakai, T., Lund-Hansen, T., Thim, L. & Kisiel, W. J. biol. Chem 265, 1890-1894 (1990)
23. Petersen, L C., Schiødt, J & Christensen, U. FEBS Lett 347, 73-79 (1994).
24. Wildgoose, P., Kazim, A L & Kisiel, W. Proc. natn Acad Sci U S.A. 87, 7290-7294 (1990).
25. Kazama, Y , Pastuszyn, A , Wildgoose, P., Hamamoto, T. & Kisiel, W. J. biol. Chem. 268, 16231-16240 (1993)
26. Tuddenham, E. G. D., Pemberton, S. & Cooper, D. N. Thromb. Haemostasis 74, 313-321 (1995).
27. Waxman, E., Laws, W. R., Laue, T. M., Nemerson, Y & Ross, J. B. A. Biochemistry 32, 3005-3012 (1993).
28. Walter, M. R. et al Nature 376, 230-235 (1995).
29. de Vos, A M , Ultsch, M. & Kossiakoff, A A. Science 255, 306-312 (1992).
30. Thim, L. et al. Biochemistry 27, 7785-7793 (1988).
31. Freedman, S. J., Furie, B. C., Furie, B & Baleja, J D. Biochemistry 34, 12126-12137 (1995).
32. Sunnerhagen, M. et al. Nature struct. Biol. 2, 504-509 (1995).
33. Schiødt, J., Harnt, N., Christensen, U. & Petersen, L. C. FEBS Lett. 306, 265-268 (1992)
34. Handford, P. A et al EMBO J. 9, 475-480 (1990).
35. Persson, E. et al. J. biol. Chem. 264, 16897-16904 (1989)
36. Bjoem, S. et al. J. biol. Chem. 266, 11051-11057 (1991).
37. Padmanabhan, K. et al. J. molec. Biol. 232, 947-966 (1993).
38. Banner, D. W. et al. Cell 73, 431-445 (1993).
39. Sabharwal, A. K et al J biol. Chem 270, 15523-15530 (1995).
40. Clackson, T. & Wells, J. A. Science 267, 383-386 (1995).
41. Brandstetter, H., Bauer, M., Huber, R., Lollar, P. & Bode, W Proc. natn. Acad. Sci. U S.A. 92, 9796-9800 (1995).
42. Husten, E. J., Esmon, C. T. & Johnson, A. E. J biol. Chem. 262, 12953-12961 (1987)
43. Mutucumarana, V. P., Duffy, E J , Lollar, P. & Johnson, A E. J. biol. Chem. 267, 17012-17021 (1992).
44. Komiyama, Y , Pedersen, A. H. & Kisiel, W. Biochemistry 29, 9418-9425 (1990).
45. Otwinowski, Z in Data Collection and Processing (eds Sawyer, L., Isaacs, N & Bailey, S) 56-62 (SERC Daresbury Laboratory Warrington, 1993).
46. Navaza, J. Acta crystallogr. A50, 157-163 (1994).
47. Collaborative Computational Project, No. 4 Acta crystallogr. D50, 760-763 (1994).
48. Brünger, A. T. X-PLOR, Version 3.1. A System for X-Ray Crystallography and NMR (Yale Univ. Press, New Haven, CT, 1992).
49. Kraulis, P. J. J appl. Crystallogr. 24, 946-950 (1991).
50. Bacon, D. J. & Anderson, W. F. J. molec. Graph. 6, 219-220 (1988).
51. Merritt, E. A. & Murphy, M. E P. Acta crystallogr. D50, 869-873 (1994).