Crystal structure of thrombin in a self-inhibited conformation

Journal of Biological Chemistry

Volumn 281, Issue 43, 2006, Pages 32922-32928

  Pineda, Agustin O ^a   Chen, Zhi Wei ^a   Bah, Alaji ^a   Garvey, Laura C ^a   Mathews, F Scott ^a   Di Cera, Enrico ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CONFORMATIONS; CRYSTAL STRUCTURE; ENZYME INHIBITION; HYDROLYSIS;

ANTICOAGULANTS; SELF-INHIBITED CONFORMATION; THROMBIN;

ENZYMES;

ARGININE; FIBRINOGEN; GUANIDINE; PROTEIN C; PROTEINASE ACTIVATED RECEPTOR 1; SODIUM ION; THROMBIN; TRYPTOPHAN;

ARTICLE; CRYSTAL STRUCTURE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE;

ALLOSTERIC REGULATION; AMINO ACID SUBSTITUTION; ARGININE; ASPARAGINE; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION; HYDROGEN BONDING; HYDROPHOBICITY; KINETICS; MODELS, MOLECULAR; MOLECULAR MIMICRY; OSMOLAR CONCENTRATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; THROMBIN; TRYPTOPHAN; WATER;

EID: 33845939797     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605530200     Document Type: Article

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