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Volumn 41, Issue 4, 2005, Pages 868-878

Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; FAT DROPLET; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

EID: 16244397057     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.20628     Document Type: Article
Times cited : (150)

References (50)
  • 2
    • 0001687866 scopus 로고    scopus 로고
    • The peroxisome biogenesis disorders
    • Scriver CR, Beaudet AL, Valle D, and Sly WS, eds. New York: McGraw-Hill
    • Gould SJ, Raymond GV, Valle D. The peroxisome biogenesis disorders. In: Scriver CR, Beaudet AL, Valle D, and Sly WS, eds. The Metabolic and Molecular Bases of Inherited Disease. New York: McGraw-Hill, 2001:3181-3217.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 3181-3217
    • Gould, S.J.1    Raymond, G.V.2    Valle, D.3
  • 3
    • 0021047742 scopus 로고
    • The cerebrohepatorenal syndrome of Zellweger, morphologic and metabolic aspects
    • Kelley RI. The cerebrohepatorenal syndrome of Zellweger, morphologic and metabolic aspects. Am J Med Genet 1983;16:503-517.
    • (1983) Am J Med Genet , vol.16 , pp. 503-517
    • Kelley, R.I.1
  • 6
    • 0019168913 scopus 로고
    • Liver in the cerebro-hepato-renal syndrome: Defective bile acid synthesis and abnormal mitochondria
    • Mathis RK, Watkins JB, Szczepanik-Van Leeuwen P, Lott IT. Liver in the cerebro-hepato-renal syndrome: defective bile acid synthesis and abnormal mitochondria. Gastroenterology 1980;79:1311-1317.
    • (1980) Gastroenterology , vol.79 , pp. 1311-1317
    • Mathis, R.K.1    Watkins, J.B.2    Szczepanik-Van Leeuwen, P.3    Lott, I.T.4
  • 8
    • 0018712604 scopus 로고
    • Licht- und elektronenmikroskopische leberbefunde beim cerebro-hepato-renalen syndrom nach zellweger (peroxisomen-defizienz)
    • Pfeifer U, Sandhage K. Licht- und Elektronenmikroskopische Leberbefunde beim Cerebro-Hepato-renalen Syndrom nach Zellweger (Peroxisomen-Defizienz). Virchows Arch A Pathol Anat Histol 1979:384:269-284.
    • (1979) Virchows Arch A Pathol Anat Histol , vol.384 , pp. 269-284
    • Pfeifer, U.1    Sandhage, K.2
  • 11
    • 0021871792 scopus 로고
    • The cerebrohepato-renal (Zellweger) syndrome: Lamellar lipid profiles in adrenocortical, hepatic mesenchymal, astrocyte cells and increased levels of very long chain fatty acids and phytanic acid in the plasma
    • Aubourg P, Robain O, Rocchiccioli F, Dancea S, Scotto J. The cerebrohepato-renal (Zellweger) syndrome: lamellar lipid profiles in adrenocortical, hepatic mesenchymal, astrocyte cells and increased levels of very long chain fatty acids and phytanic acid in the plasma. J Neurol Sci 1985;69:9-25.
    • (1985) J Neurol Sci , vol.69 , pp. 9-25
    • Aubourg, P.1    Robain, O.2    Rocchiccioli, F.3    Dancea, S.4    Scotto, J.5
  • 12
    • 0022412223 scopus 로고
    • Zellweger syndrome: Biochemical and morphological studies on two patients treated with clofibrate
    • Lazarow PB, Black V, Shio H, Fujiki Y, Hajra AK, Datta NS, et al. Zellweger syndrome: biochemical and morphological studies on two patients treated with clofibrate. Pediatr Res 1985;19:1356-1364.
    • (1985) Pediatr Res , vol.19 , pp. 1356-1364
    • Lazarow, P.B.1    Black, V.2    Shio, H.3    Fujiki, Y.4    Hajra, A.K.5    Datta, N.S.6
  • 14
    • 0034799180 scopus 로고    scopus 로고
    • Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)
    • Baumgart E, Vanhorebeek I, Grabenbauer M, Borgers M, Declercq P, Fahimi HD, et al. Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Am J Pathol 2001;159:1477-1494.
    • (2001) Am J Pathol , vol.159 , pp. 1477-1494
    • Baumgart, E.1    Vanhorebeek, I.2    Grabenbauer, M.3    Borgers, M.4    Declercq, P.5    Fahimi, H.D.6
  • 15
    • 0032898369 scopus 로고    scopus 로고
    • Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase
    • Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, et al. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic β cell-specific gene knock-outs using Cre recombinase. J Biol Chem 1999:274:305-315.
    • (1999) J Biol Chem , vol.274 , pp. 305-315
    • Postic, C.1    Shiota, M.2    Niswender, K.D.3    Jetton, T.L.4    Chen, Y.5    Moates, J.M.6
  • 16
    • 0036198394 scopus 로고    scopus 로고
    • Generation of Pex5-IoxP mice allowing the conditional elimination of peroxisomes
    • Baes M, Dewerchin M, Janssen A, Collen D, Carmeliet P. Generation of Pex5-IoxP mice allowing the conditional elimination of peroxisomes. Genesis 2002;32:177-178.
    • (2002) Genesis , vol.32 , pp. 177-178
    • Baes, M.1    Dewerchin, M.2    Janssen, A.3    Collen, D.4    Carmeliet, P.5
  • 17
    • 0035252794 scopus 로고    scopus 로고
    • Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse
    • Huyghe S, Casteels M, Janssen A, Meulders L, Mannaerts GP, Declercq PE, et al. Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse. Biochem J 2001;353:673-680.
    • (2001) Biochem J , vol.353 , pp. 673-680
    • Huyghe, S.1    Casteels, M.2    Janssen, A.3    Meulders, L.4    Mannaerts, G.P.5    Declercq, P.E.6
  • 18
    • 0027960215 scopus 로고
    • Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not
    • Hausladen A, Fridovich I. Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not. J Biol Chem 1994;269:29405-29408.
    • (1994) J Biol Chem , vol.269 , pp. 29405-29408
    • Hausladen, A.1    Fridovich, I.2
  • 19
    • 0019740345 scopus 로고
    • Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples
    • Akerboom TPM, Sies H. Assay of glutathione, glutathione disulfide, and glutathione mixed disulfides in biological samples. Methods Enzymol 1981;77:373-382.
    • (1981) Methods Enzymol , vol.77 , pp. 373-382
    • Akerboom, T.P.M.1    Sies, H.2
  • 20
    • 0030722559 scopus 로고    scopus 로고
    • The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutase
    • Sutherland MW, Learmonth BA. The tetrazolium dyes MTS and XTT provide new quantitative assays for superoxide and superoxide dismutase. Free Radic Res 1997;27:283-289.
    • (1997) Free Radic Res , vol.27 , pp. 283-289
    • Sutherland, M.W.1    Learmonth, B.A.2
  • 21
    • 0023664229 scopus 로고
    • Permeability of the peroxisomal membrane to cofactors of β-oxidation
    • Van Veldhoven PP, Just WW, Mannaerts GP. Permeability of the peroxisomal membrane to cofactors of β-oxidation, J Biol Chem 1987;262: 4310-4318.
    • (1987) J Biol Chem , vol.262 , pp. 4310-4318
    • Van Veldhoven, P.P.1    Just, W.W.2    Mannaerts, G.P.3
  • 22
    • 0023201142 scopus 로고
    • Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct
    • Wong SHY, Knight JA, Hopfer SM, Zaharia O, Leach CN, Sunderman FW. Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clin Chem 1987;33:214-220.
    • (1987) Clin Chem , vol.33 , pp. 214-220
    • Wong, S.H.Y.1    Knight, J.A.2    Hopfer, S.M.3    Zaharia, O.4    Leach, C.N.5    Sunderman, F.W.6
  • 24
    • 0023154010 scopus 로고
    • Factors underlying significant underestimation of glucokinase activity in crude liver extracts: Physiological implications of higher cellular activity
    • Davidson AL, Arion WJ. Factors underlying significant underestimation of glucokinase activity in crude liver extracts: physiological implications of higher cellular activity. Arch Biochem Biophys 1987:253:156-157.
    • (1987) Arch Biochem Biophys , vol.253 , pp. 156-157
    • Davidson, A.L.1    Arion, W.J.2
  • 25
    • 0020392647 scopus 로고
    • Pyruvate kinase isoenzymes from rat
    • Imamura K, Tanaka T. Pyruvate kinase isoenzymes from rat. Methods Enzymol 1982;90:150-165.
    • (1982) Methods Enzymol , vol.90 , pp. 150-165
    • Imamura, K.1    Tanaka, T.2
  • 26
    • 0036204534 scopus 로고    scopus 로고
    • The neuronal migration defect in mice with Zellweger syndrome (Pex5 knockout) is not caused by the inactivity of peroxisomal β-oxidation
    • Baes M, Gressens P, Huyghe S, De Nys K, Qi C, Jia Y, et al. The neuronal migration defect in mice with Zellweger syndrome (Pex5 knockout) is not caused by the inactivity of peroxisomal β-oxidation. J Neuropath Exp Neur 2002;61:368-374.
    • (2002) J Neuropath Exp Neur , vol.61 , pp. 368-374
    • Baes, M.1    Gressens, P.2    Huyghe, S.3    De Nys, K.4    Qi, C.5    Jia, Y.6
  • 27
    • 0002169455 scopus 로고
    • Glycogen. Methods of enzymatic analysis
    • Bergmeyer HU, ed. Weinheim, Germany: Verlag Chemie
    • Keppler D, Decker K. Glycogen. Methods of enzymatic analysis. In: Bergmeyer HU, ed. Metabolites 1: Carbohydrates. Weinheim, Germany: Verlag Chemie, 1984:11-18.
    • (1984) Metabolites 1: Carbohydrates , pp. 11-18
    • Keppler, D.1    Decker, K.2
  • 28
    • 0032032380 scopus 로고    scopus 로고
    • Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes
    • Honkakoski P, Negishi M. Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes. Biochem J 1998;330:889-895.
    • (1998) Biochem J , vol.330 , pp. 889-895
    • Honkakoski, P.1    Negishi, M.2
  • 29
    • 0025806764 scopus 로고
    • Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1
    • Smiley ST, Reers M, Mottola-Hartshorn C, Lin M, Chen A, Smith TW, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A 1991:88:3671-3675.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 3671-3675
    • Smiley, S.T.1    Reers, M.2    Mottola-Hartshorn, C.3    Lin, M.4    Chen, A.5    Smith, T.W.6
  • 30
    • 0036024976 scopus 로고    scopus 로고
    • Measuring mitochondrial reactive oxygen species
    • Degli Esposti M, Measuring mitochondrial reactive oxygen species. Methods 2002;26:335-340.
    • (2002) Methods , vol.26 , pp. 335-340
    • Degli Esposti, M.1
  • 33
    • 2442696086 scopus 로고    scopus 로고
    • Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARα-regulated gene expression in liver
    • Jia Y, Qi C, Kashireddi P, Surapureddi S, Zhu Y-Z, Rao MS, et al. Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARα-regulated gene expression in liver. J Biol Chem 2004;279:24427-24434.
    • (2004) J Biol Chem , vol.279 , pp. 24427-24434
    • Jia, Y.1    Qi, C.2    Kashireddi, P.3    Surapureddi, S.4    Zhu, Y.-Z.5    Rao, M.S.6
  • 34
    • 0032546929 scopus 로고    scopus 로고
    • Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase
    • Fan C-Y, Pan J, Usuda N, Yeldandi AV, Rao MS, Reddy JK. Steatohepatitis, spontaneous peroxisome proliferation and liver tumors in mice lacking peroxisomal fatty acyl-CoA oxidase. J Biol Chem 1998;273:15639-15645.
    • (1998) J Biol Chem , vol.273 , pp. 15639-15645
    • Fan, C.-Y.1    Pan, J.2    Usuda, N.3    Yeldandi, A.V.4    Rao, M.S.5    Reddy, J.K.6
  • 35
    • 10744224980 scopus 로고    scopus 로고
    • Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D- forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system
    • Jia Y, Qi C, Zhang Z, Hashimoto T, Rao MS, Huyghe S, et al. Overexpression of peroxisome proliferator-activated receptor-alpha (PPARalpha)-regulated genes in liver in the absence of peroxisome proliferation in mice deficient in both L- and D- forms of enoyl-CoA hydratase/dehydrogenase enzymes of peroxisomal beta-oxidation system. J Biol Chem 2003;278:47232-47239.
    • (2003) J Biol Chem , vol.278 , pp. 47232-47239
    • Jia, Y.1    Qi, C.2    Zhang, Z.3    Hashimoto, T.4    Rao, M.S.5    Huyghe, S.6
  • 37
    • 0042632799 scopus 로고    scopus 로고
    • Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype
    • Maxwell M, Bjorkman J, Nguyen T, Sharp P, Finnie J, Paterson C, et al. Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype. Mol Cell Biol 2003;23:5947-5957.
    • (2003) Mol Cell Biol , vol.23 , pp. 5947-5957
    • Maxwell, M.1    Bjorkman, J.2    Nguyen, T.3    Sharp, P.4    Finnie, J.5    Paterson, C.6
  • 38
    • 0842345390 scopus 로고    scopus 로고
    • Subcellular heterogeneity of mitochondrial function and dysfunction: Evidence obtained by confocal imaging
    • Kuznetsov AV, Usson Y, Leverve XMR. Subcellular heterogeneity of mitochondrial function and dysfunction: evidence obtained by confocal imaging. Mol Cell Biochem 2004;256:359-365.
    • (2004) Mol Cell Biochem , vol.256 , pp. 359-365
    • Kuznetsov, A.V.1    Usson, Y.2    Leverve, X.M.R.3
  • 39
    • 0031713986 scopus 로고    scopus 로고
    • Disorders of the mitochondria
    • Treem WR, Sokol RJ. Disorders of the mitochondria. Semin Liver Dis 1998;18:237-253.
    • (1998) Semin Liver Dis , vol.18 , pp. 237-253
    • Treem, W.R.1    Sokol, R.J.2
  • 40
    • 0030615104 scopus 로고    scopus 로고
    • Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age
    • Hansford RG, Hogue BA, Mildaziene V. Dependence of H2O2 formation by rat heart mitochondria on substrate availability and donor age. J Bioenerg Biomembr 1997;29:89-95.
    • (1997) J Bioenerg Biomembr , vol.29 , pp. 89-95
    • Hansford, R.G.1    Hogue, B.A.2    Mildaziene, V.3
  • 41
    • 0033522924 scopus 로고    scopus 로고
    • Titrating the effects of mitochondrial complex I impairment in the cell physiology
    • Barrientos A, Moraes CT. Titrating the effects of mitochondrial complex I impairment in the cell physiology. J Biol Chem 1999;274:16188-16197.
    • (1999) J Biol Chem , vol.274 , pp. 16188-16197
    • Barrientos, A.1    Moraes, C.T.2
  • 42
    • 0030056515 scopus 로고    scopus 로고
    • Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase
    • Pitkänen S, Robinson BH. Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase. J Clin Invest 1996:98:345-351.
    • (1996) J Clin Invest , vol.98 , pp. 345-351
    • Pitkänen, S.1    Robinson, B.H.2
  • 45
    • 0026654982 scopus 로고
    • Reduced activity of the electron transport chain in liver mitochondria isolated from rats with secondary biliary cirrhosis
    • Krähenbühl S, Stucki J, Reichen J. Reduced activity of the electron transport chain in liver mitochondria isolated from rats with secondary biliary cirrhosis. HEPATOLOGY 1992;15:1160-1166.
    • (1992) Hepatology , vol.15 , pp. 1160-1166
    • Krähenbühl, S.1    Stucki, J.2    Reichen, J.3
  • 46
    • 0028091169 scopus 로고
    • Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria
    • Krähenbühl S, Talos C, Fischer S, Reichen J. Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria. HEPATOLOGY 1994;19:471-479.
    • (1994) Hepatology , vol.19 , pp. 471-479
    • Krähenbühl, S.1    Talos, C.2    Fischer, S.3    Reichen, J.4
  • 48
    • 0033057924 scopus 로고    scopus 로고
    • The effect of peroxisome proliferators on mitochondrial bioenergetics
    • Zhou S, Wallace KB. The effect of peroxisome proliferators on mitochondrial bioenergetics. Toxicol Sci 1999:48:82-89.
    • (1999) Toxicol Sci , vol.48 , pp. 82-89
    • Zhou, S.1    Wallace, K.B.2
  • 49
    • 2942592344 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: Biochemical and pharmacological implications
    • Scatena R, Bottoni P, Martorana GE, Ferrari F, De Sole P, Rossi C, et al. Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications. Biochem Biophys Res Commun 2004:319:967-973.
    • (2004) Biochem Biophys Res Commun , vol.319 , pp. 967-973
    • Scatena, R.1    Bottoni, P.2    Martorana, G.E.3    Ferrari, F.4    De Sole, P.5    Rossi, C.6
  • 50
    • 0033613869 scopus 로고    scopus 로고
    • Phytanic acid activates the peroxisome proliferator-activated receptor α (PPARα) in sterol carrier protein 2-/sterol carrier protein x-deficient mice
    • Ellinghaus P, Wolfrum C, Assmann G, Spener F, Seedorf U. Phytanic acid activates the peroxisome proliferator-activated receptor α (PPARα) in sterol carrier protein 2-/sterol carrier protein x-deficient mice. J Biol Chem 1999;274:2766-2772.
    • (1999) J Biol Chem , vol.274 , pp. 2766-2772
    • Ellinghaus, P.1    Wolfrum, C.2    Assmann, G.3    Spener, F.4    Seedorf, U.5


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