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Journal of Bioenergetics and Biomembranes
Volumn 42, Issue 3, 2010, Pages 193-198
Mitochondrial matters of the brain: The role in Huntington's disease
Author keywords

Excitotoxicity; Huntington's Disease; Mitochondria; Oxidative stress; PGC 1
Indexed keywords

3 NITROPROPIONIC ACID; ALPHA TOCOPHEROL; CREATINE; FLUORODEOXYGLUCOSE F 18; HUNTINGTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PLACEBO; REMACEMIDE; UBIQUINONE; HEAT SHOCK PROTEIN; MITOCHONDRIAL PROTEIN; MUTANT PROTEIN; PPARGC1A PROTEIN, HUMAN; TRANSCRIPTION FACTOR;
EID: 77954424574     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-010-9290-y     Document Type: Review
Times cited : (40)
References (74)
  • 1
    • 0033914874 scopus 로고    scopus 로고
    • No evidence for increased oxidative damage to lipids, proteins, or DNA in Huntington's disease
    • DOI 10.1046/j.1471-4159.2000.0750840.x
    • ZI Alam B Halliwell P Jenner 2000 J Neurochem 75 840 846 10.1046/j.1471-4159.2000.0750840.x 1:CAS:528:DC%2BD3cXltFClur0%3D (Pubitemid 30485468)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.2 , pp. 840-846
    • Alam, Z.I.1    Halliwell, B.2    Jenner, P.3
  • 3
    • 0026609559 scopus 로고
    • 1:STN:280:DyaK383ivVWmuw%3D%3D
    • RL Albin JT Greenamyre 1992 Neurology 42 4 733 738 1:STN:280: DyaK383ivVWmuw%3D%3D
    • (1992) Neurology , vol.42 , Issue.4 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 5
    • 0031916812 scopus 로고    scopus 로고
    • Complex I defect in muscle from patients with Huntington's disease
    • DOI 10.1002/ana.410430321
    • J Arenas Y Campos R Ribacoba MA Martin JC Rubio P Ablanedo A Cabello 1998 Complex I defect in muscle from patients with Huntington's disease Ann. Neurol 43 397 400 10.1002/ana.410430321 1:STN:280:DyaK1c7msFertw%3D%3D (Pubitemid 28113606)
    • (1998) Annals of Neurology , vol.43 , Issue.3 , pp. 397-400
    • Arenas, J.1    Campos, Y.2    Ribacoba, R.3    Martin, M.A.4    Rubio, J.C.5    Ablanedo, P.6    Cabello, A.7
  • 8
    • 0028173480 scopus 로고
    • 10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate
    • DOI 10.1002/ana.410360613
    • MF Beal DR Henshaw BG Jenkins BR Rosen JB Schulz 1994 Ann Neurol 36 882 888 10.1002/ana.410360613 1:CAS:528:DyaK2MXjsVehsrs%3D (Pubitemid 24370928)
    • (1994) Annals of Neurology , vol.36 , Issue.6 , pp. 882-888
    • Beal, M.F.1    Henshaw, D.R.2    Jenkins, B.G.3    Rosen, B.R.4    Schulz, J.B.5
  • 11
    • 0021883670 scopus 로고
    • Regional mitochondrial respiratory activity in Huntington's disease brain
    • DOI 10.1111/j.1471-4159.1985.tb07192.x
    • WA Brennan ED Bird JR Aprille 1985 Regional mitochondrial respiratory activity in Huntington's disease brain J Neurochem 44 1948 1950 10.1111/j.1471-4159.1985.tb07192.x 1:CAS:528:DyaL2MXks12htb4%3D (Pubitemid 15047284)
    • (1985) Journal of Neurochemistry , vol.44 , Issue.6 , pp. 1948-1950
    • Brennan Jr., W.A.1    Bird, E.D.2    Aprille, J.R.3
  • 13
    • 0032581167 scopus 로고    scopus 로고
    • Trinucleotide (CAG) repeat length is positively correlated with the degree of DNA fragmentation in Huntington's disease striatum
    • DOI 10.1016/S0306-4522(98)00129-8, PII S0306452298001298
    • NJ Butterworth L Williams JY Bullock DR Love RL Faull M Dragunow 1998 Neuroscience 87 49 53 10.1016/S0306-4522(98)00129-8 1:CAS:528:DyaK1cXlt1eitL8%3D (Pubitemid 28351167)
    • (1998) Neuroscience , vol.87 , Issue.1 , pp. 49-53
    • Butterworth, N.J.1    Williams, L.2    Bullock, J.Y.3    Love, D.R.4    Faull, R.L.M.5    Dragunow, M.6
  • 15
    • 3543141113 scopus 로고    scopus 로고
    • Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release
    • DOI 10.1093/hmg/ddh162
    • YS Choo GVW Johnson M MacDonald PJ Detloff M Lesort 2004 Hum Mol Genet 13 1407 1420 10.1093/hmg/ddh162 1:CAS:528:DC%2BD2cXlt1WlsL4%3D (Pubitemid 39023049)
    • (2004) Human Molecular Genetics , vol.13 , Issue.14 , pp. 1407-1420
    • Choo, Y.S.1    Johnson, G.V.W.2    MacDonald, M.3    Detloff, P.J.4    Lesort, M.5
  • 16
    • 0033066072 scopus 로고    scopus 로고
    • 2-weighted, diffusion-weighted, and perfusion magnetic resonance imaging
    • DOI 10.1016/S0306-4522(99)00076-7, PII S0306452299000767
    • T Chyi C Chang 1999 Neurosci 92 1035 1041 10.1016/S0306-4522(99)00076-7 1:CAS:528:DyaK1MXktlCrtr0%3D (Pubitemid 29287548)
    • (1999) Neuroscience , vol.92 , Issue.3 , pp. 1035-1041
    • Chyi, T.1    Chang, C.2
  • 17
    • 56049088295 scopus 로고    scopus 로고
    • Coenzyme Q10 and vitamin e deficiency in Friedreich's ataxia: Predictor of efficacy of vitamin e and coenzyme Q10 therapy
    • 10.1111/j.1468-1331.2008.02318.x 1:STN:280:DC%2BD1cjotFyitw%3D%3D
    • JM Cooper LV Korlipara PE Hart JL Bradley AH Schapira 2008 Coenzyme Q10 and vitamin E deficiency in Friedreich's ataxia: predictor of efficacy of vitamin E and coenzyme Q10 therapy Eur J Neurol 15 1371 1379 10.1111/j.1468-1331.2008.02318.x 1:STN:280:DC%2BD1cjotFyitw%3D%3D
    • (2008) Eur J Neurol , vol.15 , pp. 1371-1379
    • Cooper, J.M.1    Korlipara, L.V.2    Hart, P.E.3    Bradley, J.L.4    Schapira, A.H.5
  • 18
    • 33749042331 scopus 로고    scopus 로고
    • Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
    • DOI 10.1016/j.cell.2006.09.015, PII S0092867406012050
    • L Cui H Jeong F Borovecki CN Parkhurst N Tanese D Krainc 2006 Cell 127 1 59 69 10.1016/j.cell.2006.09.015 1:CAS:528:DC%2BD28XhtFSitr%2FP (Pubitemid 44466642)
    • (2006) Cell , vol.127 , Issue.1 , pp. 59-69
    • Cui, L.1    Jeong, H.2    Borovecki, F.3    Parkhurst, C.N.4    Tanese, N.5    Krainc, D.6
  • 19
    • 0035369112 scopus 로고    scopus 로고
    • NMDA receptor subunits: Diversity, development and disease
    • DOI 10.1016/S0959-4388(00)00215-4
    • S Cull-Candy S Brickley M Farrant 2001 Curr Opin Neurobiol 11 327 335 10.1016/S0959-4388(00)00215-4 1:CAS:528:DC%2BD3MXks1Oktbg%3D (Pubitemid 32524098)
    • (2001) Current Opinion in Neurobiology , vol.11 , Issue.3 , pp. 327-335
    • Cull-Candy, S.1    Brickley, S.2    Farrant, M.3
  • 20
    • 0032888009 scopus 로고    scopus 로고
    • Serial 1H-NMR spectroscopy study of metabolic impairment in primates chronically treated with the succinate dehydrogenase inhibitor 3- nitropropionic acid
    • DOI 10.1006/nbdi.1999.0244
    • C Dautry F Conde E Brouillet V Mittoux MF Beal G Bloch, et al. 1999 Neurobiol Dis 6 259 268 10.1006/nbdi.1999.0244 1:CAS:528:DyaK1MXltFShsbs%3D (Pubitemid 29470037)
    • (1999) Neurobiology of Disease , vol.6 , Issue.4 , pp. 259-268
    • Dautry, C.1    Conde, F.2    Brouillet, E.3    Mittoux, V.4    Beal, M.F.5    Bloch, G.6    Hantraye, P.7
  • 21
    • 33745936901 scopus 로고    scopus 로고
    • Is MAC the knife that cuts cytochrome c from mitochondria during apoptosis?
    • DOI 10.1038/sj.cdd.4401949, PII 4401949
    • LM Dejean S Martinez-Caballero KW Kinnally 2006 Cell Death and Differentiation 13 1387 1395 10.1038/sj.cdd.4401949 1:CAS:528: DC%2BD28XmvFaitrg%3D (Pubitemid 44057474)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.8 , pp. 1387-1395
    • Dejean, L.M.1    Martinez-Caballero, S.2    Kinnally, K.W.3
  • 25
    • 34447309764 scopus 로고    scopus 로고
    • Extended polyglutamine repeats trigger a feedback loop involving the mitochondrial complex III, the proteasome and huntingtin aggregates
    • DOI 10.1093/hmg/ddm023
    • H Fukui CT Moraes 2007 Hum Mol Gen 16 7 783 797 10.1093/hmg/ddm023 1:CAS:528:DC%2BD2sXmsVWnsbc%3D (Pubitemid 47061625)
    • (2007) Human Molecular Genetics , vol.16 , Issue.7 , pp. 783-797
    • Fukui, H.1    Moraes, C.T.2
  • 27
    • 0034302893 scopus 로고    scopus 로고
    • 10.1023/A:1007608615682 1:CAS:528:DC%2BD3cXns1eitbs%3D
    • A Greco L Minghetti G Levi 2000 Neurochem Res 25 1357 1364 10.1023/A:1007608615682 1:CAS:528:DC%2BD3cXns1eitbs%3D
    • (2000) Neurochem Res , vol.25 , pp. 1357-1364
    • Greco, A.1    Minghetti, L.2    Levi, G.3
  • 31
    • 85009226418 scopus 로고    scopus 로고
    • HS Group
    • HS Group 2001 Neurology 57 397 404
    • (2001) Neurology , vol.57 , pp. 397-404
  • 37
    • 0034628981 scopus 로고    scopus 로고
    • 3-Nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: Insights into Huntington's disease
    • DOI 10.1016/S0006-8993(00)01948-X, PII S000689930001948X
    • MA La Fontaine JW Geddes A Banks DA Butterfield 2000 Brain Res 858 356 362 10.1016/S0006-8993(00)01948-X (Pubitemid 30119997)
    • (2000) Brain Research , vol.858 , Issue.2 , pp. 356-362
    • La Fontaine, M.A.1    Geddes, J.W.2    Banks, A.3    Butterfield, D.A.4
  • 39
    • 0037102256 scopus 로고    scopus 로고
    • 10.1038/nature00904 1:CAS:528:DC%2BD38XmtV2gu7o%3D
    • J Lin H Wu PT Tarr CY Zhang Z Wu O Boss, et al. 2002 Nature 418 797 801 10.1038/nature00904 1:CAS:528:DC%2BD38XmtV2gu7o%3D
    • (2002) Nature , vol.418 , pp. 797-801
    • Lin, J.1    Wu, H.2    Tarr, P.T.3    Zhang, C.Y.4    Wu, Z.5    Boss, O.6
  • 40
    • 0033914747 scopus 로고    scopus 로고
    • Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy
    • DOI 10.1002/1531-8249(200007)48:1<72::AID-ANA11>3.0.CO;2-I
    • R Lodi AH Schapira D Manners P Styles NW Wood DJ Taylor, et al. 2000 Ann Neurol 48 72 76 10.1002/1531-8249(200007)48:1<72::AID-ANA11>3.0.CO;2-I 1:STN:280:DC%2BD3czltVOitA%3D%3D (Pubitemid 30432433)
    • (2000) Annals of Neurology , vol.48 , Issue.1 , pp. 72-76
    • Lodi, R.1    Schapira, A.H.V.2    Manners, D.3    Styles, P.4    Wood, N.W.5    Taylor, D.J.6    Warner, T.T.7
  • 42
    • 0025078573 scopus 로고
    • Mitochondrial function and parental sex effect in Huntington's disease
    • 10.1016/0140-6736(90)92242-A 1:STN:280:DyaK3czns1yrtQ%3D%3D
    • VM Mann JM Cooper F Javoy-Agid Y Agid P Jenner AH Schapira 1990 Mitochondrial function and parental sex effect in Huntington's disease Lancet 336 749 10.1016/0140-6736(90)92242-A 1:STN:280:DyaK3czns1yrtQ%3D%3D
    • (1990) Lancet , vol.336 , pp. 749
    • Mann, V.M.1    Cooper, J.M.2    Javoy-Agid, F.3    Agid, Y.4    Jenner, P.5    Schapira, A.H.6
  • 46
    • 33746016268 scopus 로고    scopus 로고
    • Mitochondria: More Than Just a Powerhouse
    • DOI 10.1016/j.cub.2006.06.054, PII S0960982206017817
    • HM McBride M Neuspiel S Wasiak 2006 Curr Biol 16 14 R551 R560 10.1016/j.cub.2006.06.054 1:CAS:528:DC%2BD28XntlCrur4%3D (Pubitemid 44066793)
    • (2006) Current Biology , vol.16 , Issue.14
    • McBride, H.M.1    Neuspiel, M.2    Wasiak, S.3
  • 48
    • 0023919376 scopus 로고
    • Molecular defects of NADH-ubiquinone oxidoreductase (complex I) in mitochondrial diseases
    • 10.1007/BF00769638 1:CAS:528:DyaL1cXkslWhs74%3D
    • JA Morgan-Hughes AH Schapira JM Cooper JB Clark 1988 Molecular defects of NADH-ubiquinone oxidoreductase (complex I) in mitochondrial diseases J Bioenerg Biomembr 20 365 382 10.1007/BF00769638 1:CAS:528:DyaL1cXkslWhs74%3D
    • (1988) J Bioenerg Biomembr , vol.20 , pp. 365-382
    • Morgan-Hughes, J.A.1    Schapira, A.H.2    Cooper, J.M.3    Clark, J.B.4
  • 50
    • 0029741621 scopus 로고    scopus 로고
    • Oxidative stress and Parkinson's disease
    • 10.1111/j.1749-6632.1996.tb39064.x 1:CAS:528:DyaK28XkvFCmsrk%3D
    • AD Owen AH Schapira P Jenner CD Marsden 1996 Oxidative stress and Parkinson's disease Ann NY Acad Sci 786 217 223 10.1111/j.1749-6632.1996. tb39064.x 1:CAS:528:DyaK28XkvFCmsrk%3D
    • (1996) Ann NY Acad Sci , vol.786 , pp. 217-223
    • Owen, A.D.1    Schapira, A.H.2    Jenner, P.3    Marsden, C.D.4
  • 52
    • 0025087726 scopus 로고
    • Evidence for a defect in NADH: Ubiquinone oxidoreductase (complex I) in Huntington's disease
    • Parker WD Jr, Boyson SJ, Luder AS, Parks JK (1990) Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease. Neurology 40(8):1231-1234
    • (1990) Neurology , vol.40 , Issue.8 , pp. 1231-1234
    • Parker Jr., W.D.1    Boyson, S.J.2    Luder, A.S.3    Parks, J.K.4
  • 53
    • 0030052530 scopus 로고    scopus 로고
    • Requirement for superoxide in excitotoxic cell death
    • DOI 10.1016/S0896-6273(00)80052-5
    • M Patel BJ Day JD Crapo I Fridowich JO McNamara 1996 Neuron 16 345 355 10.1016/S0896-6273(00)80052-5 1:CAS:528:DyaK28XhtlGhsLc%3D (Pubitemid 26072367)
    • (1996) Neuron , vol.16 , Issue.2 , pp. 345-355
    • Patel, M.1    Day, B.J.2    Crapo, J.D.3    Fridovich, I.4    McNamara, J.O.5
  • 54
    • 0342635463 scopus 로고    scopus 로고
    • Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington's disease
    • DOI 10.1016/S0006-8993(00)02082-5, PII S0006899300020825
    • F Perez-Severiano C Rios J Segovia 2000 Brain Res 862 234 237 10.1016/S0006-8993(00)02082-5 1:CAS:528:DC%2BD3cXivVGhurc%3D (Pubitemid 30229791)
    • (2000) Brain Research , vol.862 , Issue.1-2 , pp. 234-237
    • Perez-Severiano, F.1    Rios, C.2    Segovia, J.3
  • 56
    • 0033965329 scopus 로고    scopus 로고
    • Higher sedentary energy expenditure in patients with Huntington's disease
    • DOI 10.1002/1531-8249(200001)47:1<64::AID-ANA11>3.0.CO;2-S
    • RE Pratley AD Salbe E Ravussin JN Caviness 2000 Ann Neurol 47 64 70 10.1002/1531-8249(200001)47:1<64::AID-ANA11>3.0.CO;2-S 1:STN:280:DC%2BD3c%2FpsF2lsQ%3D%3D (Pubitemid 30033651)
    • (2000) Annals of Neurology , vol.47 , Issue.1 , pp. 64-70
    • Pratley, R.E.1    Salbe, A.D.2    Ravussin, E.3    Caviness, J.N.4
  • 57
    • 0141493677 scopus 로고    scopus 로고
    • Excitotoxicity in Huntington disease
    • DOI 10.1016/S1566-2772(03)00054-9, PII S1566277203000549
    • L Raymond 2003 Clin Neurosci Res 3 3 121 128 10.1016/S1566-2772(03)00054- 9 1:CAS:528:DC%2BD3sXnsVKitrg%3D (Pubitemid 37168733)
    • (2003) Clinical Neuroscience Research , vol.3 , Issue.3 , pp. 121-128
    • Raymond, L.A.1
  • 58
    • 0035369784 scopus 로고    scopus 로고
    • 2+ pools in neuronal signalling
    • DOI 10.1016/S0959-4388(00)00212-9
    • R Rizzuto 2001 Curr Op Neurobiol 11 306 311 10.1016/S0959-4388(00)00212-9 1:CAS:528:DC%2BD3MXks1Oktb0%3D (Pubitemid 32524095)
    • (2001) Current Opinion in Neurobiology , vol.11 , Issue.3 , pp. 306-311
    • Rizzuto, R.1
  • 60
    • 0032851595 scopus 로고    scopus 로고
    • Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
    • DOI 10.1038/13518
    • A Sawa GW Wiegand J Cooper RL Margolis AH Sharp JF Lawler JT Greenamyre SH Snyder CA Ross 1999 Increased apoptosis of Huntington disease lymphoblast associated with repeat length-dependent mitochondrial depolarization Nat Med 5 1194 1198 10.1038/13518 1:CAS:528:DyaK1MXms1Wkt7w%3D (Pubitemid 29474426)
    • (1999) Nature Medicine , vol.5 , Issue.10 , pp. 1194-1198
    • Sawa, A.1    Wiegand, G.W.2    Cooper, J.3    Margolis, R.L.4    Sharp, A.H.5    Lawler Jr., J.F.6    Greenamyre, J.T.7    Snyder, S.H.8    Ross, C.A.9
  • 61
    • 33745410626 scopus 로고    scopus 로고
    • Mitochondrial disease
    • DOI 10.1016/S0140-6736(06)68970-8, PII S0140673606689708
    • AH Schapira 2006 Mitochondrial disease Lancet 368 70 82 10.1016/S0140-6736(06)68970-8 1:CAS:528:DC%2BD28Xms1GksLs%3D (Pubitemid 43947206)
    • (2006) Lancet , vol.368 , Issue.9529 , pp. 70-82
    • Schapira, A.H.1
  • 62
    • 0028924168 scopus 로고
    • Oxidative stress in Parkinson's disease
    • 10.1111/j.1365-2990.1995.tb01022.x 1:CAS:528:DyaK2MXkslGnu78%3D
    • AH Schapira 1995 Oxidative stress in Parkinson's disease Neuropathol Appl Neurobiol 21 3 9 10.1111/j.1365-2990.1995.tb01022.x 1:CAS:528: DyaK2MXkslGnu78%3D
    • (1995) Neuropathol Appl Neurobiol , vol.21 , pp. 3-9
    • Schapira, A.H.1
  • 63
    • 0023836601 scopus 로고
    • Molecular basis of mitochondrial myopathies: Polypeptide analysis in complex-I deficiency
    • 10.1016/S0140-6736(88)91296-2 1:CAS:528:DyaL1cXhs1GltL0%3D
    • AH Schapira JM Cooper JA Morgan-Hughes, et al. 1988 Molecular basis of mitochondrial myopathies: polypeptide analysis in complex-I deficiency Lancet 1 500 503 10.1016/S0140-6736(88)91296-2 1:CAS:528:DyaL1cXhs1GltL0%3D
    • (1988) Lancet , vol.1 , pp. 500-503
    • Schapira, A.H.1    Cooper, J.M.2    Morgan-Hughes, J.A.3
  • 65
    • 33749557821 scopus 로고    scopus 로고
    • Cytotoxicity of a mutant huntingtin fragment in yeast involves early alterations in mitochondrial OXPHOS complexes II and III
    • DOI 10.1093/hmg/ddl248
    • A Solans A Zambrano M Rodríguez A Barrientos 2006 Hum Mol Genet 15 20 3063 3081 10.1093/hmg/ddl248 1:CAS:528:DC%2BD28XhtVOgt7%2FO (Pubitemid 44530710)
    • (2006) Human Molecular Genetics , vol.15 , Issue.20 , pp. 3063-3081
    • Solans, A.1    Zambrano, A.2    Rodriguez, M.3    Barrientos, A.4
  • 66
    • 0016259560 scopus 로고
    • Biochemical abnormalities in Huntington's chorea brains
    • 1:STN:280:DyaE2c3pvVOntw%3D%3D
    • WL Stahl PD Swanson 1974 Biochemical abnormalities in Huntington's chorea brains Neurology 24 813 819 1:STN:280:DyaE2c3pvVOntw%3D%3D
    • (1974) Neurology , vol.24 , pp. 813-819
    • Stahl, W.L.1    Swanson, P.D.2
  • 71
    • 35348941757 scopus 로고    scopus 로고
    • Clinical correlates of mitochondrial function in Huntington's disease muscle
    • DOI 10.1002/mds.21540
    • C Turner JM Cooper AH Schapira Turner 2007 Mov Disord 22 12 1715 1721 10.1002/mds.21540 (Pubitemid 47597594)
    • (2007) Movement Disorders , vol.22 , Issue.12 , pp. 1715-1721
    • Turner, C.1    Cooper, J.M.2    Schapira, A.H.V.3

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