Pathomechanisms underlying X-adrenoleukodystrophy: A three-hit hypothesis

Brain Pathology

Volumn 20, Issue 4, 2010, Pages 838-844

  Singh, Inderjit ^a   Pujol, Aurora ^b,c,d  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^c INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^d CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

Author keywords

Axonal degeneration; Demyelination; Neuroinflammation; Oxidative stress; Peroxisomes; Plasmalogens; VLCFA; X adrenoleukodystrophy

Indexed keywords

ABC TRANSPORTER; ABCD1 TRANSPORTER; ALPHA TOCOPHEROL; LORENZO OIL; UNCLASSIFIED DRUG; VERY LONG CHAIN FATTY ACID; ABCD1 PROTEIN, HUMAN; FATTY ACID;

ADRENOLEUKODYSTROPHY; ALLERGIC ENCEPHALOMYELITIS; APOPTOSIS; BRAIN CORTEX; CHILDHOOD ADRENOLEUKODYSTROPHY; CONFERENCE PAPER; CYTOTOXICITY; DEMYELINATION; DISEASE COURSE; FATTY ACID OXIDATION; GENE EXPRESSION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LOSS OF FUNCTION MUTATION; METABOLIC DISORDER; MOLECULAR GENETICS; NERVE FIBER DEGENERATION; NEUROPATHOLOGY; NEWBORN SCREENING; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; RISK FACTOR; X CHROMOSOME LINKED DISORDER; BRAIN; GENETICS; NERVE DEGENERATION; PATHOLOGY;

ADRENOLEUKODYSTROPHY; ATP-BINDING CASSETTE TRANSPORTERS; BRAIN; FATTY ACIDS; HUMANS; NERVE DEGENERATION; OXIDATIVE STRESS;

EID: 77953191945     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2010.00392.x     Document Type: Conference Paper

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