Activation of CysLT receptors induces astrocyte proliferation and death after oxygen-glucose deprivation

GLIA

Volumn 56, Issue 1, 2008, Pages 27-37

  Huang, Xiao Jia ^a,b   Zhang, Wei Ping ^a   Li, Cheng Tan ^a   Shi, Wen Zhen ^a   Fang, San Hua ^a   Lu, Yun Bi ^a   Chen, Zhong ^a   Wei, Er Qing ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b JIANGSU UNIVERSITY   (China)

Author keywords

5 lipoxygenase; Astrocytosis; Cysteinyl leukotriene receptors; Cysteinyl leukotrienes; Glial cells; Ischemia

Indexed keywords

6 (4 CARBOXYPHENYLTHIO) 5 HYDROXY 7,9,11,14 ICOSATETRAENOIC ACID; ARACHIDONATE 5 LIPOXYGENASE; BAY CYSLT 2; GLUCOSE; LEUKOTRIENE D4; MESSENGER RNA; MONTELUKAST; OXYGEN; PEPTIDOLEUKOTRIENE; PEPTIDOLEUKOTRIENE RECEPTOR ANTAGONIST; PHOSPHOLIPASE A2; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; IN VITRO STUDY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN;

ANIMALS; ANIMALS, NEWBORN; ARACHIDONATE 5-LIPOXYGENASE; ASTROCYTES; BLOTTING, WESTERN; CELL COUNT; CELL DEATH; CELL HYPOXIA; CELL PROLIFERATION; CELL SURVIVAL; ENZYME ACTIVATION; EXTRACELLULAR SPACE; GLUCOSE; IMMUNOHISTOCHEMISTRY; LEUKOTRIENE D4; MEMBRANE PROTEINS; RATS; RECEPTORS, LEUKOTRIENE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 36448939414     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20588     Document Type: Article

References (37)

1. Amrani Y, Moore PE, Hoffman R, Shore SA, Panettieri RA, Jr. 2001. Interferon-γ modulates cysteinyl leukotriene receptor-1 expression and function in human airway myocytes. Am J Respir Crit Care Med 164:2098-2101.
2. Ballerini P, Ciccarelli R, Caciagli F, Rathbone MP, Werstiuk ES, Traversa U, Buccella S, Giuliani P, Jang S, Nargi E, Visini D, Santavenere C, Di Iorio P. 2005. P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl leukotrienes. Int J Immunopathol Pharmacol 18:417-430.
3. Beller TC, Friend DS, Maekawa A, Lam BK, Austen KF, Kanaoka Y. 2004a. Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis. Proc Natl Acad Sci USA 101:3047-3052.
4. Beller TC, Maekawa A, Friend DS, Austen KF, Kanaoka Y. 2004b. Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice. J Biol Chem 279:46129-46134.
5. Bosetti F. 2007. Arachidonic acid metabolism in brain physiology and pathology: Lessons from genetically altered mouse models. J Neurochem 102:577-586.
6. Brink C, Dahlen SE, Drazen J, Evans JF, Hay DW, Nicosia S, Serhan CN, Shimizu T, Yokomizo T. 2003. International Union of Pharmacology XXXVII. Nomenclature for leukotriene and lipoxin receptors. Pharmacol Rev 55:195-227.
7. Capra V. 2004. Molecular and functional aspects of human cysteinyl leukotriene receptors. Pharmacol Res 50:1-11.
8. Capra V, Thompson MD, Sala A, Cole DE, Folco G, Rovati GE. 2007. Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: Critical update and emerging trends. Med Res Rev 27:469-527.
9. Chavez JC, Baranova O, Lin J, Pichiule P. 2006. The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J Neurosci 26:9471-9481.
10. Chen-Roetling J, Regan RF. 2006. Effect of heme oxygenase-1 on the vulnerability of astrocytes and neurons to hemoglobin. Biochem Biophys Res Commun 350:233-237.
11. Ciccarelli R, D'Alimonte I, Ballerini P, D'Auro M, Nargi E, Buccella S, Di Iorio P, Bruno V, Nicoletti F, Caciagli F. 2007. Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes. Mol Pharmacol 71:1369-1380.
12. Ciccarelli R, D'Alimonte I, Santavenere C, D'Auro M, Ballerini P, Nargi E, Buccella S, NicosiaFolco S, Caciagli F, Di Iorio P. 2004. Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. Eur J Neurosci 20:1514-1524.
13. Dringen R, Hamprecht B. 1998. Glutathione restoration as indicator for cellular metabolism of astroglial cells. Dev Neurosci 20:401-407.
14. Early SB, Barekzi E, Negri J, Hise K, Borish L, Steinke JW. 2007. Concordant modulation of cysteinyl leukotriene receptor expression by IL-4 and IFN-γ on peripheral immune cells. Am J Respir Cell Mol Biol 36:715-720.
15. Espinosa K, Bosse Y, Stankova J, Rola-Pleszczynski M. 2003. CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4. J Allergy Clin Immunol 111:1032-1040.
16. Fang SH, Wei EQ, Zhou Y, Wang ML, Zhang WP, Yu GL, Chu LS, Chen Z. 2006. Increased expression of cysteinyl leukotriene receptor-1 in the brain mediates neuronal damage and astrogliosis after focal cerebral ischemia in rats. Neuroscience 140:969-979.
17. Fang SH, Zhou Y, Chu LS, Zhang WP, Wang ML, Yu GL, Peng F, Wei EQ. 2007. Spatio-temporal expression of cysteinyl leukotriene receptor-2 mRNA in rat brain after focal cerebral ischemia. Neurosci Lett 412:78-83.
18. Ge QF, Wei EQ, Zhang WP, Hu X, Huang XJ, Zhang L, Song Y, Ma ZQ, Chen Z, Luo JH. 2006. Activation of 5-lipoxygenase after oxygen-glucose deprivation is partly mediated via NMDA receptor in rat cortical neurons. J Neurochem 97:992-1004.
19. Heise CE, O'Dowd BF, Figueroa DJ, Sawyer N, Nguyen T, Im DS, Stocco R, Bellefeuille JN, Abramovitz M, Cheng R, Williams DL Jr, Zeng Z, Liu Q, Ma L, Clements MK, Coulombe N, Liu Y, Austin CP, George SR, O'Neill GP, Metters KM, Lynch KR, Evans JF. 2000. Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem 275:30531-30536.
20. Jatana M, Giri S, Ansari MA, Elango C, Singh AK, Singh I, Khan M. 2006. Inhibition of NF-κB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia. J Neuroinflammation 3:12.
21. Kanaoka Y, Boyce JA. 2004. Cysteinyl leukotrienes and their receptors: Cellular distribution and function in immune and inflammatory responses. J Immunol 173:1503-1510.
22. Kim E, Raval AP, Defazio RA, Perez-Pinzon MA. 2007. Ischemic preconditioning via epsilon protein kinase C activation requires cyclooxygenase-2 activation in vitro. Neuroscience 145:931-941.
23. Kintner DB, Look A, Shull GE, Sun D. 2005. Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2. Am J Physiol Cell Physiol 289:C934-C945.
24. Liu HT, Tashmukhamedov BA, Inoue H, Okada Y, Sabirov RZ. 2006. Roles of two types of anion channels in glutamate release from mouse astrocytes under ischemic or osmotic stress. Glia 54:343-357.
25. Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metiers KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z, Connolly BM, Bai C, Austin CP, Chateauneuf A, Stocco R, Greig GM, Kargman S, Hooks SB, Hosfield E, Williams DL Jr, Ford-Hutchinson AW, Caskey CT, Evans JF. 1999. Characterization of the human cysteinyl leukotriene CysLT1 receptor. Nature 399:789-793.
26. Panickar KS, Norenberg MD. 2005. Astrocytes in cerebral ischemic injury: Morphological and general considerations. Glia 50:287-298.
27. Re DB, Nafia I, Melon C, Shimamoto K, Kerkerian-Le GL, Had-Aissouni L. 2006. Glutamate leakage from a compartmentalized intracellular metabolic pool and activation of the lipoxygenase pathway mediate oxidative astrocyte death by reversed glutamate transport. Glia 54:47-57.
28. Seregi A, Simmet T, Schobert A, Hertting G. 1990. Characterization of cysteinyl-leukotriene formation in primary astroglial cell cultures. J Pharm Pharmacol 42:191-193.
29. Sheng WW, Li CT, Zhang WP, Yuan YM, Hu H, Fang SH, Zhang L, Wei EQ. 2006. Distinct roles of CysLT1 and CysLT2 receptors in oxygen glucose deprivation-induced PC12 cell death. Biochem Biophys Res Commun 346:19-25.
30. Song Y, Wei EQ, Zhang WP, Zhang L, Liu JR, Chen Z. 2004. Minocycline protects PC12 cells from ischemic-like injury and inhibits 5-lipoxygenase activation. Neuroreport 15:2181-2184.
31. Thoren AE, Helps SC, Nilsson M, Sims NR. 2006. The metabolism of C-glucose by neurons and astrocytes in brain subregions following focal cerebral ischemia in rats. J Neurochem 97:968-978.
32. Wang ML, Huang XJ, Fang SH, Yuan YM, Zhang WP, Lu YB, Ding Q, Wei EQ. 2006. Leukotriene D4 induces brain edema and enhances CysLT2 receptor-mediated aquaporin 4 expression. Biochem Biophys Res Commun 350:399-404.
33. Wang Q, Tang XN, Yenari MA. 2007. The inflammatory response in stroke. J Neuroimmunol 184:53-68.
34. Woszczek G, Chen LY, Nagineni S, Alsaaty S, Harry A, Logun C, Pawliczak R, Shelhamer JH. 2007. IFN-γ induces cysteinyl leukotriene receptor 2 expression and enhances the responsiveness of human endothelial cells to cysteinyl leukotrienes. J Immunol 178:5262-5270.
35. Yu GL, Wei EQ, Wang ML, Zhang WP, Zhang SH, Weng JQ, Chu LS, Fang SH, Zhou Y, Chen Z, Zhang Q, Zhang LH. 2005. Pranlukast, a cysteinyl leukotriene receptor-1 antagonist, protects against chronic ischemic brain injury and inhibits the glial scar formation in mice. Brain Res 1053:116-125.
36. Zhao G, Flavin MP. 2000. Differential sensitivity of rat hippocampal and cortical astrocytes to oxygen-glucose deprivation injury. Neurosci Lett 285:177-180.
37. Zhou Y, Wei EQ, Fang SH, Chu LS, Wang ML, Zhang WP, Yu GL, Ye YL, Lin SC, Chen Z. 2006. Spatio-temporal properties of 5-lipoxygenase expression and activation in the brain after focal cerebral ischemia in rats. Life Sci 79:1645-1656.