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Volumn 19, Issue 10, 2010, Pages 2005-2014

Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy

(16)  Fourcade, Stéphane a,b   Ruiz, Montserrat a,b   Guilera, Cristina a,b   Hahnen, Eric c,d   Brichta, Lars c,m   Naudi, Alba e   Portero Otín, Manuel e   Dacremont, Georges f   Cartier, Nathalie g   Wanders, Ronald h   Kemp, Stephan h   Mandel, Jean Louis i,j,k   Wirth, Brunhilde c   Pamplona, Reinald e   Aubourg, Patrick g   Pujol, Aurora a,b,l  


Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; PROTEIN ABCD2; REACTIVE OXYGEN METABOLITE; RNA; UNCLASSIFIED DRUG; VALPROIC ACID; VERY LONG CHAIN FATTY ACID;

EID: 77952508899     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddq082     Document Type: Article
Times cited : (79)

References (63)
  • 4
    • 0029783210 scopus 로고    scopus 로고
    • The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae
    • Hettema, E.H., van Roermund, C.W., Distel, B., van den Berg, M., Vilela, C., Rodrigues-Pousada, C., Wanders, R.J. and Tabak, H.F. (1996) The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae. EMBO J., 15, 3813-3822.
    • (1996) EMBO J. , vol.15 , pp. 3813-3822
    • Hettema, E.H.1    van Roermund, C.W.2    Distel, B.3    van den Berg, M.4    Vilela, C.5    Rodrigues-Pousada, C.6    Wanders, R.J.7    Tabak, H.F.8
  • 5
    • 0029011568 scopus 로고
    • PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene
    • Shani, N., Watkins, P.A. and Valle, D. (1995) PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene. Proc. Natl Acad. Sci. USA, 92, 6012-6016.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 6012-6016
    • Shani, N.1    Watkins, P.A.2    Valle, D.3
  • 10
    • 10744231450 scopus 로고    scopus 로고
    • Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease
    • Saunthararajah, Y., Hillery, C.A., Lavelle, D., Molokie, R., Dorn, L., Bressler, L., Gavazova, S., Chen, Y.H., Hoffman, R. and DeSimone, J. (2003) Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease. Blood, 102, 3865-3870.
    • (2003) Blood , vol.102 , pp. 3865-3870
    • Saunthararajah, Y.1    Hillery, C.A.2    Lavelle, D.3    Molokie, R.4    Dorn, L.5    Bressler, L.6    Gavazova, S.7    Chen, Y.H.8    Hoffman, R.9    DeSimone, J.10
  • 11
    • 0038725634 scopus 로고    scopus 로고
    • Pharmacological strategies for muscular dystrophy
    • Khurana, T.S. and Davies, K.E. (2003) Pharmacological strategies for muscular dystrophy. Nat. Rev. Drug Discov., 2, 379-390.
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 379-390
    • Khurana, T.S.1    Davies, K.E.2
  • 14
    • 65549121495 scopus 로고    scopus 로고
    • Human ATP-binding cassette (ABC) transporter family
    • Vasiliou, V., Vasiliou, K. and Nebert, D.W. (2009) Human ATP-binding cassette (ABC) transporter family. Hum. Genomics, 3, 281-290.
    • (2009) Hum. Genomics , vol.3 , pp. 281-290
    • Vasiliou, V.1    Vasiliou, K.2    Nebert, D.W.3
  • 15
    • 0030034602 scopus 로고    scopus 로고
    • A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern
    • Lombard-Platet, G., Savary, S., Sarde, C.O., Mandel, J.L. and Chimini, G. (1996) A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern. Proc. Natl Acad. Sci. USA, 93, 1265-1269.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 1265-1269
    • Lombard-Platet, G.1    Savary, S.2    Sarde, C.O.3    Mandel, J.L.4    Chimini, G.5
  • 18
    • 0032924991 scopus 로고    scopus 로고
    • Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy
    • Netik, A., Forss-Petter, S., Holzinger, A., Molzer, B., Unterrainer, G. and Berger, J. (1999) Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy. Hum. Mol. Genet., 8, 907-913.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 907-913
    • Netik, A.1    Forss-Petter, S.2    Holzinger, A.3    Molzer, B.4    Unterrainer, G.5    Berger, J.6
  • 21
    • 0036501313 scopus 로고    scopus 로고
    • Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy
    • Pujol, A., Hindelang, C., Callizot, N., Bartsch, U., Schachner, M. and Mandel, J.L. (2002) Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy. Hum. Mol. Genet., 11, 499-505.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 499-505
    • Pujol, A.1    Hindelang, C.2    Callizot, N.3    Bartsch, U.4    Schachner, M.5    Mandel, J.L.6
  • 23
    • 33846942956 scopus 로고    scopus 로고
    • X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism, ABC half-transporters and the complicated route to treatment
    • Kemp, S. and Wanders, R.J. (2007) X-linked adrenoleukodystrophy: very long-chain fatty acid metabolism, ABC half-transporters and the complicated route to treatment. Mol. Genet. Metab., 90, 268-276.
    • (2007) Mol. Genet. Metab. , vol.90 , pp. 268-276
    • Kemp, S.1    Wanders, R.J.2
  • 26
    • 33746065340 scopus 로고    scopus 로고
    • Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity
    • Leng, Y. and Chuang, D.M. (2006) Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity. J. Neurosci., 26, 7502-7512.
    • (2006) J. Neurosci. , vol.26 , pp. 7502-7512
    • Leng, Y.1    Chuang, D.M.2
  • 27
    • 33645282527 scopus 로고    scopus 로고
    • Valproic acid promotes neurite outgrowth in PC12 cells independent from regulation of the survival of motoneuron protein
    • van Bergeijk, J., Haastert, K., Grothe, C. and Claus, P. (2006) Valproic acid promotes neurite outgrowth in PC12 cells independent from regulation of the survival of motoneuron protein. Chem. Biol. Drug. Des., 67, 244-247.
    • (2006) Chem. Biol. Drug. Des. , vol.67 , pp. 244-247
    • van Bergeijk, J.1    Haastert, K.2    Grothe, C.3    Claus, P.4
  • 29
    • 36248958610 scopus 로고    scopus 로고
    • Valproic acid treatment in six patients with spinal muscular atrophy
    • Tsai, L.K., Yang, C.C., Hwu, W.L. and Li, H. (2007) Valproic acid treatment in six patients with spinal muscular atrophy. Eur. J. Neurol., 14, e8-e9.
    • (2007) Eur. J. Neurol. , vol.14
    • Tsai, L.K.1    Yang, C.C.2    Hwu, W.L.3    Li, H.4
  • 30
    • 33747083488 scopus 로고    scopus 로고
    • Valproate may improve strength and function in patients with type III/IV spinal muscle atrophy
    • Weihl, C.C., Connolly, A.M. and Pestronk, A. (2006) Valproate may improve strength and function in patients with type III/IV spinal muscle atrophy. Neurology, 67, 500-501.
    • (2006) Neurology , vol.67 , pp. 500-501
    • Weihl, C.C.1    Connolly, A.M.2    Pestronk, A.3
  • 33
    • 19744370528 scopus 로고    scopus 로고
    • Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy
    • Asheuer, M., Bieche, I., Laurendeau, I., Moser, A., Hainque, B., Vidaud, M. and Aubourg, P. (2005) Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy. Hum. Mol. Genet., 14, 1293-1303.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 1293-1303
    • Asheuer, M.1    Bieche, I.2    Laurendeau, I.3    Moser, A.4    Hainque, B.5    Vidaud, M.6    Aubourg, P.7
  • 34
    • 2442448425 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity by valproic acid blocks adipogenesis
    • Lagace, D.C. and Nachtigal, M.W. (2004) Inhibition of histone deacetylase activity by valproic acid blocks adipogenesis. J. Biol. Chem., 279, 18851-18860.
    • (2004) J. Biol. Chem. , vol.279 , pp. 18851-18860
    • Lagace, D.C.1    Nachtigal, M.W.2
  • 35
    • 33645106534 scopus 로고    scopus 로고
    • S-2-Pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides
    • Eikel, D., Hoffmann, K., Zoll, K., Lampen, A. and Nau, H. (2006) S-2-Pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides. Drug. Metab. Dispos., 34, 612-620.
    • (2006) Drug. Metab. Dispos. , vol.34 , pp. 612-620
    • Eikel, D.1    Hoffmann, K.2    Zoll, K.3    Lampen, A.4    Nau, H.5
  • 36
    • 77951247066 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the Alzheimer amyloid precursor protein
    • Epub ahead of print February
    • Venkataramani, V., Rossner, C., Iffland, L., Schweyer, S., Tamboli, I., Walter, J., Wirths, O. and Bayer, T.A. The histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the Alzheimer amyloid precursor protein. J. Biol. Chem., 2010; Epub ahead of print February 9.
    • (2010) J. Biol. Chem. , pp. 9
    • Venkataramani, V.1    Rossner, C.2    Iffland, L.3    Schweyer, S.4    Tamboli, I.5    Walter, J.6    Wirths, O.7    Bayer, T.A.8
  • 38
    • 58749085411 scopus 로고    scopus 로고
    • Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts
    • Uto, T., Contreras, M.A., Gilg, A.G. and Singh, I. (2008) Oxidative imbalance in nonstimulated X-adrenoleukodystrophy-derived lymphoblasts. Dev. Neurosci., 30, 410-418.
    • (2008) Dev. Neurosci. , vol.30 , pp. 410-418
    • Uto, T.1    Contreras, M.A.2    Gilg, A.G.3    Singh, I.4
  • 40
    • 0035793088 scopus 로고    scopus 로고
    • Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins
    • Requena, J.R., Chao, C.C., Levine, R.L. and Stadtman, E.R. (2001) Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins. Proc. Natl Acad. Sci. USA, 98, 69-74.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 69-74
    • Requena, J.R.1    Chao, C.C.2    Levine, R.L.3    Stadtman, E.R.4
  • 41
    • 0346731073 scopus 로고    scopus 로고
    • Maillard reaction products in tissue proteins: new products and new perspectives
    • Thorpe, S.R. and Baynes, J.W. (2003) Maillard reaction products in tissue proteins: new products and new perspectives. Amino Acids, 25, 275-281.
    • (2003) Amino Acids , vol.25 , pp. 275-281
    • Thorpe, S.R.1    Baynes, J.W.2
  • 43
    • 0026067570 scopus 로고
    • Molecular species of phosphatidylcholine containing very long chain fatty acids in human brain: enrichment in X-linked adrenoleukodystrophy brain and diseases of peroxisome biogenesis brain
    • Sharp, P., Johnson, D. and Poulos, A. (1991) Molecular species of phosphatidylcholine containing very long chain fatty acids in human brain: enrichment in X-linked adrenoleukodystrophy brain and diseases of peroxisome biogenesis brain. J. Neurochem., 56, 30-37.
    • (1991) J. Neurochem. , vol.56 , pp. 30-37
    • Sharp, P.1    Johnson, D.2    Poulos, A.3
  • 44
    • 0025827397 scopus 로고
    • Comparison of valproate concentrations in human plasma CSF and brain tissue after administration of different formulations of valproate or valpromide
    • Wieser, H.G. (1991) Comparison of valproate concentrations in human plasma, CSF and brain tissue after administration of different formulations of valproate or valpromide. Epilepsy Res., 9, 154-159.
    • (1991) Epilepsy Res. , vol.9 , pp. 154-159
    • Wieser, H.G.1
  • 45
    • 58049206781 scopus 로고    scopus 로고
    • Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition
    • Hauke, J., Riessland, M., Lunke, S., Eyupoglu, I.Y., Blumcke, I., El-Osta, A., Wirth, B. and Hahnen, E. (2009) Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition. Hum. Mol. Genet., 18, 304-317.
    • (2009) Hum. Mol. Genet. , vol.18 , pp. 304-317
    • Hauke, J.1    Riessland, M.2    Lunke, S.3    Eyupoglu, I.Y.4    Blumcke, I.5    El-Osta, A.6    Wirth, B.7    Hahnen, E.8
  • 46
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini, L., Buchs, P.A. and Muller, D. (1991) A simple method for organotypic cultures of nervous tissue. J. Neurosci. Methods, 37, 173-182.
    • (1991) J. Neurosci. Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 47
    • 58149234400 scopus 로고    scopus 로고
    • A multiple-loop, double-cube microarray design applied to prostate cancer cell lines with variable sensitivity to histone deacetylase inhibitors
    • Kortenhorst, M.S., Zahurak, M., Shabbeer, S., Kachhap, S., Galloway, N., Parmigiani, G., Verheul, H.M. and Carducci, M.A. (2008) A multiple-loop, double-cube microarray design applied to prostate cancer cell lines with variable sensitivity to histone deacetylase inhibitors. Clin. Cancer Res., 14, 6886-6894.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 6886-6894
    • Kortenhorst, M.S.1    Zahurak, M.2    Shabbeer, S.3    Kachhap, S.4    Galloway, N.5    Parmigiani, G.6    Verheul, H.M.7    Carducci, M.A.8
  • 48
    • 33646018341 scopus 로고    scopus 로고
    • Fatty acid elongases in mammals: their regulation and roles in metabolism
    • Jakobsson, A., Westerberg, R. and Jacobsson, A. (2006) Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog. Lipid. Res., 45, 237-249.
    • (2006) Prog. Lipid. Res. , vol.45 , pp. 237-249
    • Jakobsson, A.1    Westerberg, R.2    Jacobsson, A.3
  • 50
    • 51349148504 scopus 로고    scopus 로고
    • Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids
    • Agbaga, M.P., Brush, R.S., Mandal, M.N., Henry, K., Elliott, M.H. and Anderson, R.E. (2008) Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids. Proc. Natl Acad. Sci. USA, 105, 12843-12848.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 12843-12848
    • Agbaga, M.P.1    Brush, R.S.2    Mandal, M.N.3    Henry, K.4    Elliott, M.H.5    Anderson, R.E.6
  • 51
    • 34047174936 scopus 로고    scopus 로고
    • Loss of functional ELOVL4 depletes very long-chain fatty acids (> or = C28) and the unique omega-O-acylceramides in skin leading to neonatal death
    • Vasireddy, V., Uchida, Y., Salem, N. Jr, Kim, S.Y., Mandal, M.N., Reddy, G.B., Bodepudi, R., Alderson, N.L., Brown, J.C., Hama, H. et al. (2007) Loss of functional ELOVL4 depletes very long-chain fatty acids (> or = C28) and the unique omega-O-acylceramides in skin leading to neonatal death. Hum. Mol. Genet., 16, 471-482.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 471-482
    • Vasireddy, V.1    Uchida, Y.2    Salem N., Jr.3    Kim, S.Y.4    Mandal, M.N.5    Reddy, G.B.6    Bodepudi, R.7    Alderson, N.L.8    Brown, J.C.9    Hama, H.10
  • 52
    • 44149128885 scopus 로고    scopus 로고
    • Steroid hormones control circadian Elovl3 expression in mouse liver
    • Brolinson, A., Fourcade, S., Jakobsson, A., Pujol, A. and Jacobsson, A. (2008) Steroid hormones control circadian Elovl3 expression in mouse liver. Endocrinology, 149, 3158-3166.
    • (2008) Endocrinology , vol.149 , pp. 3158-3166
    • Brolinson, A.1    Fourcade, S.2    Jakobsson, A.3    Pujol, A.4    Jacobsson, A.5
  • 53
    • 60849093466 scopus 로고    scopus 로고
    • Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
    • Rothstein, J.D. (2009) Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann. Neurol., 65 (Suppl. 1), S3-S9.
    • (2009) Ann. Neurol. , vol.65 , Issue.SUPPL. 1
    • Rothstein, J.D.1
  • 54
    • 57649155208 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance
    • Zhou, C., Huang, Y. and Przedborski, S. (2008) Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance. Ann. N. Y. Acad. Sci., 1147, 93-104.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1147 , pp. 93-104
    • Zhou, C.1    Huang, Y.2    Przedborski, S.3
  • 57
    • 68849099411 scopus 로고    scopus 로고
    • Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage
    • Bachmann, R.F., Wang, Y., Yuan, P., Zhou, R., Li, X., Alesci, S., Du, J. and Manji, H.K. (2009) Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage. Int. J. Neuropsychopharmacol., 12, 805-822.
    • (2009) Int. J. Neuropsychopharmacol. , vol.12 , pp. 805-822
    • Bachmann, R.F.1    Wang, Y.2    Yuan, P.3    Zhou, R.4    Li, X.5    Alesci, S.6    Du, J.7    Manji, H.K.8
  • 58
    • 33846303907 scopus 로고    scopus 로고
    • Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate
    • Cui, J., Shao, L., Young, L.T. and Wang, J.F. (2007) Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate. Neuroscience, 144, 1447-1453.
    • (2007) Neuroscience , vol.144 , pp. 1447-1453
    • Cui, J.1    Shao, L.2    Young, L.T.3    Wang, J.F.4
  • 59
    • 33646863671 scopus 로고    scopus 로고
    • Cytoprotection by lithium and valproate varies between cell types and cellular stresses
    • Lai, J.S., Zhao, C., Warsh, J.J. and Li, P.P. (2006) Cytoprotection by lithium and valproate varies between cell types and cellular stresses. Eur. J. Pharmacol., 539, 18-26.
    • (2006) Eur. J. Pharmacol. , vol.539 , pp. 18-26
    • Lai, J.S.1    Zhao, C.2    Warsh, J.J.3    Li, P.P.4
  • 60
    • 33845411261 scopus 로고    scopus 로고
    • Oxidative stress as a mechanism of valproic acid-associated hepatotoxicity
    • Chang, T.K. and Abbott, F.S. (2006) Oxidative stress as a mechanism of valproic acid-associated hepatotoxicity. Drug Metab. Rev., 38, 627-639.
    • (2006) Drug Metab. Rev. , vol.38 , pp. 627-639
    • Chang, T.K.1    Abbott, F.S.2
  • 61
    • 70350463946 scopus 로고    scopus 로고
    • Carnitine in the treatment of valproic acid-induced toxicity
    • Lheureux, P.E. and Hantson, P. (2009) Carnitine in the treatment of valproic acid-induced toxicity. Clin. Toxicol. (Phila.), 47, 101-111.
    • (2009) Clin. Toxicol. (Phila.) , vol.47 , pp. 101-111
    • Lheureux, P.E.1    Hantson, P.2
  • 62
    • 0038371327 scopus 로고
    • Synthesis and applications of isotopically labeled compounds
    • Baillie, T. and Jones, J. R. (eds), Elsevier, Amsterdam
    • ten Brink, H., Jacobs, C. and Bickelhaupt, F. (1989) Synthesis and applications of isotopically labeled compounds. In Baillie, T. and Jones, J.R. (eds), Synthesis and Applications of Isotopically Labelled Compounds. Elsevier, Amsterdam, pp. 723-726.
    • (1989) Synthesis and Applications of Isotopically Labelled Compounds , pp. 723-726
    • ten Brink, H.1    Jacobs, C.2    Bickelhaupt, F.3


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