-
1
-
-
0035155759
-
Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP
-
Andreassen O. A., Ferrante R. J., Dedeoglu A., Albers D. W., Klivenyi P., Carlson E. J., Epstein C. J. and Beal M. F. (2001) Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. Exp. Neurol. 167, 189-195.
-
(2001)
Exp. Neurol.
, vol.167
, pp. 189-195
-
-
Andreassen, O.A.1
Ferrante, R.J.2
Dedeoglu, A.3
Albers, D.W.4
Klivenyi, P.5
Carlson, E.J.6
Epstein, C.J.7
Beal, M.F.8
-
2
-
-
10744226316
-
Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice
-
Bayer T. A., Schafer S., Simons A. et al. (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice. Proc. Natl Acad. Sci. USA 100, 14187-14192.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 14187-14192
-
-
Bayer, T.A.1
Schafer, S.2
Simons, A.3
-
3
-
-
0028233494
-
Hydrogen peroxide mediates amyloid beta protein toxicity
-
Behl C., Davis J. B., Lesley R. and Schubert D. (1994) Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 77, 817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
4
-
-
0029417023
-
Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
-
Busciglio J. and Yankner B. A. (1995) Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro. Nature 378, 776-779.
-
(1995)
Nature
, vol.378
, pp. 776-779
-
-
Busciglio, J.1
Yankner, B.A.2
-
5
-
-
0036905921
-
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: Implications for neurodegeneration in Alzheimer's disease brain
-
Butterfield D. A. (2002) Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. Free Radic. Res. 36, 1307-1313.
-
(2002)
Free Radic. Res.
, vol.36
, pp. 1307-1313
-
-
Butterfield, D.A.1
-
6
-
-
0035877756
-
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
-
Chishti M. A., Yang D. S., Janus C. et al. (2001) Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J. Biol. Chem. 276, 21562-21570.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21562-21570
-
-
Chishti, M.A.1
Yang, D.S.2
Janus, C.3
-
7
-
-
12244281810
-
Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model
-
Drake J., Link C. D. and Butterfield D. A. (2003) Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model. Neurobiol. Aging 24, 415-420.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 415-420
-
-
Drake, J.1
Link, C.D.2
Butterfield, D.A.3
-
8
-
-
0033153450
-
Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations
-
Guo Q., Fu W., Holtsberg F. W., Steiner S. M. and Mattson M. P. (1999) Superoxide mediates the cell-death-enhancing action of presenilin-1 mutations. J. Neurosci. Res. 56, 457-470.
-
(1999)
J. Neurosci. Res.
, vol.56
, pp. 457-470
-
-
Guo, Q.1
Fu, W.2
Holtsberg, F.W.3
Steiner, S.M.4
Mattson, M.P.5
-
9
-
-
0033363939
-
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
-
Iadecola C., Zhang F., Niwa K., Eckman C., Turner S. K., Fischer E., Younkin S., Borchelt D. R., Hsiao K. K. and Carlson G. A. (1999) SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein. Nat. Neurosci. 2, 157-161.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 157-161
-
-
Iadecola, C.1
Zhang, F.2
Niwa, K.3
Eckman, C.4
Turner, S.K.5
Fischer, E.6
Younkin, S.7
Borchelt, D.R.8
Hsiao, K.K.9
Carlson, G.A.10
-
10
-
-
0035818998
-
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP
-
Kamal A., Almenar-Queralt A., LeBlanc J. F., Roberts E. A. and Goldstein L. S. (2001) Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP. Nature 414, 643-648.
-
(2001)
Nature
, vol.414
, pp. 643-648
-
-
Kamal, A.1
Almenar-Queralt, A.2
LeBlanc, J.F.3
Roberts, E.A.4
Goldstein, L.S.5
-
11
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
Lim G. P., Chu T., Yang F., Beech W., Frautschy S. A. and Cole G. M. (2001) The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. 21, 8370-8377.
-
(2001)
J. Neurosci.
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
12
-
-
2642545220
-
The oxidative damage theory of aging
-
Lin M. T. and Beal M. F. (2003) The oxidative damage theory of aging. Clin. Neurosci. Res. 2, 305-315.
-
(2003)
Clin. Neurosci. Res.
, vol.2
, pp. 305-315
-
-
Lin, M.T.1
Beal, M.F.2
-
13
-
-
0032733691
-
The role of oxidative stress in Alzheimer disease
-
Markesbery W. R. (1999) The role of oxidative stress in Alzheimer disease. Arch. Neurol. 56, 1449-1452.
-
(1999)
Arch. Neurol.
, vol.56
, pp. 1449-1452
-
-
Markesbery, W.R.1
-
14
-
-
0037444553
-
In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy
-
McLellan M. E., Kajdasz S. T., Hyman B. T. and Bacskai B. J. (2003) In vivo imaging of reactive oxygen species specifically associated with thioflavine S-positive amyloid plaques by multiphoton microscopy. J. Neurosci. 23, 2212-2217.
-
(2003)
J. Neurosci.
, vol.23
, pp. 2212-2217
-
-
McLellan, M.E.1
Kajdasz, S.T.2
Hyman, B.T.3
Bacskai, B.J.4
-
15
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
Mecocci P., MacGarvey U. and Beal M. F. (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann. Neurol. 36, 747-751.
-
(1994)
Ann. Neurol.
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Beal, M.F.3
-
16
-
-
0034643895
-
Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells
-
Misonou H., Morishima-Kawashima M. and Ihara Y. (2000) Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells. Biochemistry 39, 6951-6959.
-
(2000)
Biochemistry
, vol.39
, pp. 6951-6959
-
-
Misonou, H.1
Morishima-Kawashima, M.2
Ihara, Y.3
-
17
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
Nunomura A., Perry G., Aliev G. et al. (2001) Oxidative damage is the earliest event in Alzheimer disease. J. Neuropathol. Exp. Neurol. 60, 759-767.
-
(2001)
J. Neuropathol. Exp. Neurol.
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
-
18
-
-
0038578900
-
Selective increase in cellular A beta 42 is related to apoptosis but not necrosis
-
Ohyagi Y., Yamada T., Nishioka K., Clarke N. J., Tomlinson A. J., Naylor S., Nakabeppu Y., Kira J. and Younkin S. G. (2000) Selective increase in cellular A beta 42 is related to apoptosis but not necrosis. Neuroreport 11, 167-171.
-
(2000)
Neuroreport
, vol.11
, pp. 167-171
-
-
Ohyagi, Y.1
Yamada, T.2
Nishioka, K.3
Clarke, N.J.4
Tomlinson, A.J.5
Naylor, S.6
Nakabeppu, Y.7
Kira, J.8
Younkin, S.G.9
-
19
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
-
Pratico D., Uryu K., Leight S., Trojanoswki J. Q. and Lee V. M. (2001) Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J. Neurosci. 21, 4183-4187.
-
(2001)
J. Neurosci.
, vol.21
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanoswki, J.Q.4
Lee, V.M.5
-
20
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study
-
Sano M., Ernesto C., Thomas R. G. et al. (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study. N. Engl. J. Med. 336, 1216-1222.
-
(1997)
N. Engl. J. Med.
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
-
21
-
-
0036829434
-
Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain
-
Smith M. A., Casadesus G., Joseph J. A. and Perry G. (2002) Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radic. Biol. Med. 33, 1194-1199.
-
(2002)
Free Radic. Biol. Med.
, vol.33
, pp. 1194-1199
-
-
Smith, M.A.1
Casadesus, G.2
Joseph, J.A.3
Perry, G.4
-
22
-
-
0036827031
-
Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology
-
Takahashi R. H., Milner T. A., Li F., Nam E. E., Edgar M. A., Yamaguchi H., Beal M. F., Xu H., Greengard P. and Gouras G. K. (2002) Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am. J. Pathol. 161, 1869-1879.
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1869-1879
-
-
Takahashi, R.H.1
Milner, T.A.2
Li, F.3
Nam, E.E.4
Edgar, M.A.5
Yamaguchi, H.6
Beal, M.F.7
Xu, H.8
Greengard, P.9
Gouras, G.K.10
-
23
-
-
0035108135
-
Alzheimer's disease in man and transgenic mice: Females at higher risk
-
Turner R. J. (2001) Alzheimer's disease in man and transgenic mice: females at higher risk. Am. J. Pathol. 158, 797-801.
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 797-801
-
-
Turner, R.J.1
-
24
-
-
0033102629
-
Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse
-
Van Remmen H., Salvador C., Yang H., Huang T. T., Epstein C. J. and Richardson A. (1999) Characterization of the antioxidant status of the heterozygous manganese superoxide dismutase knockout mouse. Arch. Biochem. Biophys. 363, 91-97.
-
(1999)
Arch. Biochem. Biophys.
, vol.363
, pp. 91-97
-
-
Van Remmen, H.1
Salvador, C.2
Yang, H.3
Huang, T.T.4
Epstein, C.J.5
Richardson, A.6
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