-
2
-
-
84900202571
-
Hormonal influences on aging and lifespan
-
In: Wolf NS, editor, Netherlands: Springer
-
Spong A, Bartke A (2010). Hormonal influences on aging and lifespan. In: Wolf NS, editor. Comparative biology of aging. Netherlands: Springer, 43-68.
-
(2010)
Comparative biology of aging
, pp. 43-68
-
-
Spong, A.1
Bartke, A.2
-
3
-
-
0036358167
-
Growth negatively impacts the life span of mammals
-
Rollo CD (2002). Growth negatively impacts the life span of mammals. Evol Develop, 4:55-61.
-
(2002)
Evol Develop
, vol.4
, pp. 55-61
-
-
Rollo, C.D.1
-
4
-
-
34548392453
-
Overview of research on giant transgenic mice with emphasis on the brain and aging
-
In: Samaras T, editor., New York: Nova Scientific Publishers
-
Rollo CD (2007). Overview of research on giant transgenic mice with emphasis on the brain and aging. In: Samaras T, editor. Human body size and the laws of scaling. New York: Nova Scientific Publishers, 235-60.
-
(2007)
Human body size and the laws of scaling
, pp. 235-260
-
-
Rollo, C.D.1
-
5
-
-
84900203221
-
Animal size, metabolic rate, and survival, among and within species
-
In: Wolf NS, editor., Netherlands: Springer
-
Austad SN (2010). Animal size, metabolic rate, and survival, among and within species. In: Wolf NS, editor. The comparative biology of aging. Netherlands: Springer, 27-41.
-
(2010)
The comparative biology of aging
, pp. 27-41
-
-
Austad, S.N.1
-
6
-
-
0029952098
-
Dwarf mice and the ageingprocess
-
Brown-Borg HM, Borg KE, Meliska CJ, Bartke A (1996). Dwarf mice and the ageingprocess. Nature, 384:33.
-
(1996)
Nature
, vol.384
, pp. 33
-
-
Brown-Borg, H.M.1
Borg, K.E.2
Meliska, C.J.3
Bartke, A.4
-
7
-
-
0033581704
-
shc adaptor protein controls oxidative stress response and life span in mammals
-
shc adaptor protein controls oxidative stress response and life span in mammals. Nature, 402:309-13.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
8
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M; Dupont J; Ducos B; Leneuve P; Geloen A; Evens P; Cervera P; LeBouc Y (2003). IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature, 421:182-7.
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Evens, P.6
Cervera, P.7
LeBouc, Y.8
-
9
-
-
33646731782
-
Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction
-
Bonkowski MS, Rocha JS, Masternak MM, Al Regaiey KA, Bartke A (2006). Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc. Natl. Acad. Sci. USA, 103:7901-5.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 7901-7905
-
-
Bonkowski, M.S.1
Rocha, J.S.2
Masternak, M.M.3
Al Regaiey, K.A.4
Bartke, A.5
-
10
-
-
34547097247
-
Brain IRS2 signaling coordinates life span and nutrient homeostasis
-
Taguchi A, Wartschow LM, White MF (2007). Brain IRS2 signaling coordinates life span and nutrient homeostasis. Science, 317:369-72.
-
(2007)
Science
, vol.317
, pp. 369-372
-
-
Taguchi, A.1
Wartschow, L.M.2
White, M.F.3
-
11
-
-
40449142493
-
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
-
Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson ICA, Thornton JM, Gems D, Partridge L, Withers DJ (2008). Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. FASEB J, 22:807-18.
-
(2008)
FASEB J
, vol.22
, pp. 807-818
-
-
Selman, C.1
Lingard, S.2
Choudhury, A.I.3
Batterham, R.L.4
Claret, M.5
Clements, M.6
Ramadani, F.7
Okkenhaug, K.8
Schuster, E.9
Blanc, E.10
Piper, M.D.11
Al-Qassab, H.12
Speakman, J.R.13
Carmignac, D.14
Robinson, I.C.A.15
Thornton, J.M.16
Gems, D.17
Partridge, L.18
Withers, D.J.19
-
12
-
-
0027345682
-
Premature aging in transgenic mice expressing different growth hormone genes
-
Steger RW; Bartke A; Cecim M (1993). Premature aging in transgenic mice expressing different growth hormone genes. J Reprod Fert, 46:61-75.
-
(1993)
J Reprod Fert
, vol.46
, pp. 61-75
-
-
Steger, R.W.1
Bartke, A.2
Cecim, M.3
-
13
-
-
0027178438
-
Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models
-
Wolf E, Kahnt E, Ehrlein J, Hermanns W, Brem G, Wanke R (1993). Effects of long-term elevated serum levels of growth hormone on life expectancy of mice: Lessons from transgenic animal models. Mech. Ageing Develop, 68:71-87.
-
(1993)
Mech. Ageing Develop
, vol.68
, pp. 71-87
-
-
Wolf, E.1
Kahnt, E.2
Ehrlein, J.3
Hermanns, W.4
Brem, G.5
Wanke, R.6
-
14
-
-
0000689299
-
Accelerated aging of giant transgenic growth hormone mice is associated with elevated free radical processes
-
Rollo CD, Carlson J, Sawada M (1996). Accelerated aging of giant transgenic growth hormone mice is associated with elevated free radical processes. Can J Zool, 74:606-20.
-
(1996)
Can J Zool
, vol.74
, pp. 606-620
-
-
Rollo, C.D.1
Carlson, J.2
Sawada, M.3
-
15
-
-
0003754649
-
Phenotypes: Their Epigenetics, Ecology and Evolution
-
London: Chapman and Hall
-
Rollo CD. Phenotypes: Their Epigenetics, Ecology and Evolution. London: Chapman and Hall; 1994.
-
(1994)
-
-
Rollo, C.D.1
-
16
-
-
9444223924
-
Disruption of yeast forkhead-associated cell cycle transcription by oxidative stress
-
Shapira M, Segal E, Botstein D (2004). Disruption of yeast forkhead-associated cell cycle transcription by oxidative stress. Mol Biol Cell, 5:5659-69.
-
(2004)
Mol Biol Cell
, vol.5
, pp. 5659-5669
-
-
Shapira, M.1
Segal, E.2
Botstein, D.3
-
17
-
-
27744511769
-
Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients
-
Kaeberlein M, Powers RW III, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK (2005). Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science, 310:1193-6.
-
(2005)
Science
, vol.310
, pp. 1193-1196
-
-
Kaeberlein, M.1
Powers III, R.W.2
Steffen, K.K.3
Westman, E.A.4
Hu, D.5
Dang, N.6
Kerr, E.O.7
Kirkland, K.T.8
Fields, S.9
Kennedy, B.K.10
-
18
-
-
34247630099
-
Growth control of the eukaryote cell: a systems biology study in yeast.
-
Castrillo JI, Zeef LA, Hoyle DC, Zhang N, Hayes A, Gardner DCJ, Cornell MJ, Petty J, Hakes L, Wardleworth L, Rash B, Brown M, Dunn WB, Broadhurst D, O'Donoghue K, Hester SS, Dunkley TPJ, Hart SR, Swainston N, Li P, Gaskell SJ, Paton NW, Lilley KS, Kell DB, Oliver SG (2007). Growth control of the eukaryote cell: a systems biology study in yeast. J Biol, 6:4
-
(2007)
J Biol
, vol.6
, pp. 4
-
-
Castrillo, J.I.1
Zeef, L.A.2
Hoyle, D.C.3
Zhang, N.4
Hayes, A.5
Gardner, D.C.J.6
Cornell, M.J.7
Petty, J.8
Hakes, L.9
Wardleworth, L.10
Rash, B.11
Brown, M.12
Dunn, W.B.13
Broadhurst, D.14
O'Donoghue, K.15
Hester, S.S.16
Dunkley, T.P.J.17
Hart, S.R.18
Swainston, N.19
Li, P.20
Gaskell, S.J.21
Paton, N.W.22
Lilley, K.S.23
Kell, D.B.24
Oliver, S.G25
more..
-
19
-
-
38749112941
-
Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast
-
Brauer MJ, Huttenhower C, Airoldi EM, Rosenstein R, Matese JC, Gresham D, Boer VM, Troyanskaya OG, Botstein D (2008). Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast. Mol Biol Cell, 19:352-367.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 352-367
-
-
Brauer, M.J.1
Huttenhower, C.2
Airoldi, E.M.3
Rosenstein, R.4
Matese, J.C.5
Gresham, D.6
Boer, V.M.7
Troyanskaya, O.G.8
Botstein, D.9
-
20
-
-
80755127803
-
Circadian Redox Regulation
-
In: Pantopoulos, K, Schipper HM editors., New York: Nova Science Publishers (In Press).
-
Rollo CD (2010) Circadian Redox Regulation. In: Pantopoulos, K, Schipper HM editors. Principles of free radical biomedicine. New York: Nova Science Publishers (In Press).
-
(2010)
Principles of free radical biomedicine
-
-
Rollo, C.D.1
-
21
-
-
21044450084
-
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress
-
Salmon AB, Murakami S, Bartke A, Kopchick J, Yasumura K, Miller RA (2005). Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am J Physiol Endocrinol Metab, 289:E23-E29.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
, pp. E23-E29
-
-
Salmon, A.B.1
Murakami, S.2
Bartke, A.3
Kopchick, J.4
Yasumura, K.5
Miller, R.A.6
-
22
-
-
0001600049
-
Evidence for a trade-offbetween growth and behavioural activity in giant "Supermice" genetically engineered with extra copies of growth hormone genes
-
Lachmansingh E, Rollo CD (1994). Evidence for a trade-offbetween growth and behavioural activity in giant "Supermice" genetically engineered with extra copies of growth hormone genes. Can J Zool, 72:2158-68.
-
(1994)
Can J Zool
, vol.72
, pp. 2158-2168
-
-
Lachmansingh, E.1
Rollo, C.D.2
-
23
-
-
0030872731
-
Behavioural rhythmicity in transgenic growth hormone mice: trade-offs, energetics, and sleep-wake cycles
-
Rollo CD, Foss J, Lachmansingh E, Singh R (1997). Behavioural rhythmicity in transgenic growth hormone mice: trade-offs, energetics, and sleep-wake cycles. Can J Zool, 75:1020-34.
-
(1997)
Can J Zool
, vol.75
, pp. 1020-1034
-
-
Rollo, C.D.1
Foss, J.2
Lachmansingh, E.3
Singh, R.4
-
24
-
-
0036080702
-
Sleep of transgenic mice producing excess rat growth hormone
-
Hajdu I, Obal F Jr, Fang J, Krueger JM, Rollo CD (2002). Sleep of transgenic mice producing excess rat growth hormone. Am J Physiol Regul Integr Comp Physiol, 282:R70-R76.
-
(2002)
Am J Physiol Regul Integr Comp Physiol
, vol.282
, pp. R70-R76
-
-
Hajdu, I.1
Obal Jr., F.2
Fang, J.3
Krueger, J.M.4
Rollo, C.D.5
-
25
-
-
62349097087
-
Dopamine and aging: intersecting facets
-
Rollo CD (2009). Dopamine and aging: intersecting facets. Neurochem Res, 34:601-29.
-
(2009)
Neurochem Res
, vol.34
, pp. 601-629
-
-
Rollo, C.D.1
-
26
-
-
0032863142
-
Involvement of glutathione in the regulation of respiratory oscillation during a continuous culture of Saccharomyces cerevisiae
-
Murray DB, Engelen F, Lloyd D, Kuriyama, H (1999). Involvement of glutathione in the regulation of respiratory oscillation during a continuous culture of Saccharomyces cerevisiae. Microbiol, 145:2739-45.
-
(1999)
Microbiol
, vol.145
, pp. 2739-2745
-
-
Murray, D.B.1
Engelen, F.2
Lloyd, D.3
Kuriyama, H.4
-
27
-
-
0036831077
-
Cycles of mitochondrial energization driven by the ultradian clock in a continuous culture of Saccharomyces cerevisiae
-
Lloyd D, Eshantha L, Salgado J, Turner MP, Suller MTE, Murray D (2002). Cycles of mitochondrial energization driven by the ultradian clock in a continuous culture of Saccharomyces cerevisiae. Microbiol, 148:3715-24.
-
(2002)
Microbiol
, vol.148
, pp. 3715-3724
-
-
Lloyd, D.1
Eshantha, L.2
Salgado, J.3
Turner, M.P.4
Suller, M.T.E.5
Murray, D.6
-
28
-
-
34248598677
-
Redox rhythmicity: clocks at the core of temporal coherence
-
Lloyd D, Murray DB (2007). Redox rhythmicity: clocks at the core of temporal coherence. Bioessays, 29:465-73.
-
(2007)
Bioessays
, vol.29
, pp. 465-473
-
-
Lloyd, D.1
Murray, D.B.2
-
29
-
-
0842277806
-
An ultradian clock shapes genome expression in yeast
-
Young MW (2004). An ultradian clock shapes genome expression in yeast. Proc. Natl. Acad. Sci USA, 101:1118-9.
-
(2004)
Proc. Natl. Acad. Sci USA
, vol.101
, pp. 1118-1119
-
-
Young, M.W.1
-
30
-
-
33747591416
-
Metabolic cycles as an underlying basis of biological oscillations
-
Tu BP, McKnight SL (2006). Metabolic cycles as an underlying basis of biological oscillations. Nature Rev Mol Cell Biol, 7:696-701.
-
(2006)
Nature Rev Mol Cell Biol
, vol.7
, pp. 696-701
-
-
Tu, B.P.1
McKnight, S.L.2
-
31
-
-
48249135677
-
The yeast metabolic cycle: insights into the life of a eukaryotic cell
-
Tu BP, McKnight SL (2007). The yeast metabolic cycle: insights into the life of a eukaryotic cell. Cold Spring Harb Symp Quant Biol, 72:339-43.
-
(2007)
Cold Spring Harb Symp Quant Biol
, vol.72
, pp. 339-343
-
-
Tu, B.P.1
McKnight, S.L.2
-
32
-
-
27944487902
-
Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes
-
Tu BP, Kudlicki A, Rowicka M, McKnight SL (2005). Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Science, 310:1152-8.
-
(2005)
Science
, vol.310
, pp. 1152-1158
-
-
Tu, B.P.1
Kudlicki, A.2
Rowicka, M.3
McKnight, S.L.4
-
33
-
-
36749067297
-
Cyclic changes in metabolic state during the life of a yeast cell
-
Tu BP, Mohler RE, Liu JC, Dombek KM, Young ET, Synovec RE, McKnight SL (2007). Cyclic changes in metabolic state during the life of a yeast cell. Proc. Natl. Acad. Sci. USA, 104:16886-91.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 16886-16891
-
-
Tu, B.P.1
Mohler, R.E.2
Liu, J.C.3
Dombek, K.M.4
Young, E.T.5
Synovec, R.E.6
McKnight, S.L.7
-
34
-
-
4544362674
-
Mammalian circadian biology: elucidating genome-wide levels of temporal organization
-
Lowrey PL, Takahashi JS (2004). Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Ann Rev Gen Hum Genet, 5:407-41.
-
(2004)
Ann Rev Gen Hum Genet
, vol.5
, pp. 407-441
-
-
Lowrey, P.L.1
Takahashi, J.S.2
-
35
-
-
77951912759
-
Circadian organization of behavior and physiology in Drosophila
-
20.
-
Allada C, Chung BY (2010). Circadian organization of behavior and physiology in Drosophila. Ann Rev Physiol, 72:26.2-26.20.
-
(2010)
Ann Rev Physiol
, vol.72
, Issue.26
, pp. 2-26
-
-
Allada, C.1
Chung, B.Y.2
-
36
-
-
76149141225
-
Metabolism and circadian rhythms- implications for obesity
-
Froy O (2010). Metabolism and circadian rhythms- implications for obesity. Endocr Rev, 31:1-24.
-
(2010)
Endocr Rev
, vol.31
, pp. 1-24
-
-
Froy, O.1
-
37
-
-
77953454534
-
Effect of feeding regimens on circadian rhythms: Implications for aging and longevity
-
Froy O, Miskin R (2010). Effect of feeding regimens on circadian rhythms: Implications for aging and longevity. Aging, 2:7-27.
-
(2010)
Aging
, vol.2
, pp. 7-27
-
-
Froy, O.1
Miskin, R.2
-
38
-
-
18444414586
-
Coordinated transcription of key pathways in the mouse by the circadian clock
-
Panda S, Antoch MP, Miller BH, Su AI, Schook AB, Straume M, Schultz PG, Kay SA, Takahashi JS, Hogenesch JB (2002). Coordinated transcription of key pathways in the mouse by the circadian clock. Cell, 109:307-20.
-
(2002)
Cell
, vol.109
, pp. 307-320
-
-
Panda, S.1
Antoch, M.P.2
Miller, B.H.3
Su, A.I.4
Schook, A.B.5
Straume, M.6
Schultz, P.G.7
Kay, S.A.8
Takahashi, J.S.9
Hogenesch, J.B.10
-
39
-
-
34548853967
-
Identification of the circadian transcriptome in adult mouse skeletal muscle
-
McCarthy JJ, Andrews JL, McDearmon EL, Campbell KS, Barber BK, Miller BH, Walker JR, Hogenesch JB, Takahashi JS, Esser KA (2007). Identification of the circadian transcriptome in adult mouse skeletal muscle. Physiol Genomics, 31:86-95.
-
(2007)
Physiol Genomics
, vol.31
, pp. 86-95
-
-
McCarthy, J.J.1
Andrews, J.L.2
McDearmon, E.L.3
Campbell, K.S.4
Barber, B.K.5
Miller, B.H.6
Walker, J.R.7
Hogenesch, J.B.8
Takahashi, J.S.9
Esser, K.A.10
-
40
-
-
33747154772
-
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
-
Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ (2006). Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell, 126: 789-99.
-
(2006)
Cell
, vol.126
, pp. 789-799
-
-
Bookout, A.L.1
Jeong, Y.2
Downes, M.3
Yu, R.T.4
Evans, R.M.5
Mangelsdorf, D.J.6
-
41
-
-
33747157406
-
Nuclear receptor expression links the circadian clock to metabolism
-
Yang X, Downes M, Yu RT, Bookout AL, He W, Straume M, Mangelsdorf DJ, Evans RM (2006). Nuclear receptor expression links the circadian clock to metabolism. Cell, 126:801-10.
-
(2006)
Cell
, vol.126
, pp. 801-810
-
-
Yang, X.1
Downes, M.2
Yu, R.T.3
Bookout, A.L.4
He, W.5
Straume, M.6
Mangelsdorf, D.J.7
Evans, R.M.8
-
42
-
-
77950957354
-
A wheel of time: the circadian clock, nuclear receptors, and physiology
-
Yang, X (2010). A wheel of time: the circadian clock, nuclear receptors, and physiology. Genes Dev, 24:741-747.
-
(2010)
Genes Dev
, vol.24
, pp. 741-747
-
-
Yang, X.1
-
43
-
-
33646145721
-
Circadian regulator CLOCK is a histone acetyltransferase
-
Doi M, Hirayama J, Sassone-Corsi P (2006). Circadian regulator CLOCK is a histone acetyltransferase. Cell, 125:497-508.
-
(2006)
Cell
, vol.125
, pp. 497-508
-
-
Doi, M.1
Hirayama, J.2
Sassone-Corsi, P.3
-
44
-
-
33845611615
-
Interplay of circadian clocks and metabolic rhythms
-
Wijnen H, Young MW (2006). Interplay of circadian clocks and metabolic rhythms. Ann Rev Genet, 40:409-48.
-
(2006)
Ann Rev Genet
, vol.40
, pp. 409-448
-
-
Wijnen, H.1
Young, M.W.2
-
45
-
-
37249086610
-
Rev-erbα, a heme sensor that coordinates metabolic and circadian pathways
-
Yin L, Wu N, Curtin JC, Qatanani M, Szwergold NR, Reid RA, Waitt GM, Parks DJ, Pearce KH, Wisely GB, Lazar MA (2007). Rev-erbα, a heme sensor that coordinates metabolic and circadian pathways. Science, 318:1786-9.
-
(2007)
Science
, vol.318
, pp. 1786-1789
-
-
Yin, L.1
Wu, N.2
Curtin, J.C.3
Qatanani, M.4
Szwergold, N.R.5
Reid, R.A.6
Waitt, G.M.7
Parks, D.J.8
Pearce, K.H.9
Wisely, G.B.10
Lazar, M.A.11
-
46
-
-
0035997367
-
Metabolism and the control of circadian rhythms
-
Rutter J, Reick M, McKnight SL (2001). Metabolism and the control of circadian rhythms. Ann Rev Biochem, 71:307-31.
-
(2001)
Ann Rev Biochem
, vol.71
, pp. 307-331
-
-
Rutter, J.1
Reick, M.2
McKnight, S.L.3
-
47
-
-
35548930677
-
High-fat diet disrupts behavioral and molecular circadian rhythms in mice
-
Kohsaka A, Laposky AD, Ramsey KM, Estrada C, Joshu C, Kobayashi Y, Turek FW, Bass J (2007). High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab, 6:414-21.
-
(2007)
Cell Metab
, vol.6
, pp. 414-421
-
-
Kohsaka, A.1
Laposky, A.D.2
Ramsey, K.M.3
Estrada, C.4
Joshu, C.5
Kobayashi, Y.6
Turek, F.W.7
Bass, J.8
-
48
-
-
66749096504
-
Physiologic and health consequences of circadian disruption in animal models
-
Laposky AD, Turek FW (2009). Physiologic and health consequences of circadian disruption in animal models. Sleep Med Clin, 4:127-42.
-
(2009)
Sleep Med Clin
, vol.4
, pp. 127-142
-
-
Laposky, A.D.1
Turek, F.W.2
-
49
-
-
76749139528
-
The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors
-
Schmutz I, Ripperger JA, Baeriswyl-Aebischer S, Albrecht U (2010). The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors. Genes Dev, 24:345-57.
-
(2010)
Genes Dev
, vol.24
, pp. 345-357
-
-
Schmutz, I.1
Ripperger, J.A.2
Baeriswyl-Aebischer, S.3
Albrecht, U.4
-
50
-
-
73449091515
-
Rev-erb-α: an integrator of circadian rhythms and metabolism
-
Duez H, Staels B (2009). Rev-erb-α: an integrator of circadian rhythms and metabolism. J Appl Physiol, 107:1972-80.
-
(2009)
J Appl Physiol
, vol.107
, pp. 1972-1980
-
-
Duez, H.1
Staels, B.2
-
51
-
-
66049149024
-
Identification of an endogenous ligand bound to a native orphan nuclear receptor.
-
Yuan X, Ta TC, Lin M, Evans JR, Dong Y, Bolotin E, Sherman MA, Forman BM, Sladek FM (2009). Identification of an endogenous ligand bound to a native orphan nuclear receptor. PLoS ONE, 4(5): e5609
-
(2009)
PLoS ONE
, vol.4
, Issue.5
-
-
Yuan, X.1
Ta, T.C.2
Lin, M.3
Evans, J.R.4
Dong, Y.5
Bolotin, E.6
Sherman, M.A.7
Forman, B.M.8
Sladek, F.M9
-
52
-
-
40049109300
-
Nuclear hormone receptors for heme: REV-ERBα and REV-ERBß are ligand-regulated components of the mammalian clock
-
Burris TP (2008). Nuclear hormone receptors for heme: REV-ERBα and REV-ERBß are ligand-regulated components of the mammalian clock. Mol Endocrinol, 22:1509-20.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1509-1520
-
-
Burris, T.P.1
-
53
-
-
43049138812
-
Orphan nuclear receptor NOR-1 enhances cAMP-dependent uncoupling protein-1 gene transcription
-
Kumar N, Liu D, Wang H, Robidoux J, Collins S (2008). Orphan nuclear receptor NOR-1 enhances cAMP-dependent uncoupling protein-1 gene transcription. Mol Endocrinol, 22:1057-64.
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1057-1064
-
-
Kumar, N.1
Liu, D.2
Wang, H.3
Robidoux, J.4
Collins, S.5
-
54
-
-
44249088564
-
The orphan nuclear receptor, NOR-1, a target of ß-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle
-
Pearen MA, Myers SA, Raichur S, Ryall JG, Lynch GS, Muscat GEO (2008). The orphan nuclear receptor, NOR-1, a target of ß-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle. Endocrinol, 149:2853-65.
-
(2008)
Endocrinol
, vol.149
, pp. 2853-2865
-
-
Pearen, M.A.1
Myers, S.A.2
Raichur, S.3
Ryall, J.G.4
Lynch, G.S.5
Muscat, G.E.O.6
-
55
-
-
33748663947
-
Transcriptional profiling in the adrenal gland reveals circadian regulation of hormone biosynthesis genes and nucleosome assembly genes
-
Oster H, Damerow S, Hut RA, Eichele G (2006). Transcriptional profiling in the adrenal gland reveals circadian regulation of hormone biosynthesis genes and nucleosome assembly genes. J Biol Rhythms, 21:350-61.
-
(2006)
J Biol Rhythms
, vol.21
, pp. 350-361
-
-
Oster, H.1
Damerow, S.2
Hut, R.A.3
Eichele, G.4
-
56
-
-
58549095056
-
Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production
-
Son GH, Chung S, Choe HK, Kim HD, Baik SM, Lee H, Lee HW, Choi S, Sun W, Kim H, Cho S, Lee KH, Kim K (2008). Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc. Natl. Acad. Sci. USA, 105:20970-5.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20970-20975
-
-
Son, G.H.1
Chung, S.2
Choe, H.K.3
Kim, H.D.4
Baik, S.M.5
Lee, H.6
Lee, H.W.7
Choi, S.8
Sun, W.9
Kim, H.10
Cho, S.11
Lee, K.H.12
Kim, K.13
-
57
-
-
66449103104
-
The role of mPer2 clock gene in glucocorticoid and feeding rhythms
-
Yang S, Liu A, Weidenhammer A, Cooksey RC, McClain D, Kim MK, Aguilera G, Abel ED, Chung JH (2009). The role of mPer2 clock gene in glucocorticoid and feeding rhythms. Endocrinol, 150:2153-60.
-
(2009)
Endocrinol
, vol.150
, pp. 2153-2160
-
-
Yang, S.1
Liu, A.2
Weidenhammer, A.3
Cooksey, R.C.4
McClain, D.5
Kim, M.K.6
Aguilera, G.7
Abel, E.D.8
Chung, J.H.9
-
58
-
-
33750906556
-
The redox regulation of PI3-Kinase-dependent signaling
-
Leslie NR (2006). The redox regulation of PI3-Kinase-dependent signaling. Antioxid Redox Signal, 8:1765-74.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1765-1774
-
-
Leslie, N.R.1
-
59
-
-
57649234905
-
Autophagy genes and ageing
-
Vellai T (2009). Autophagy genes and ageing. Cell Death Different, 16:94-102.
-
(2009)
Cell Death Different
, vol.16
, pp. 94-102
-
-
Vellai, T.1
-
60
-
-
75449088805
-
The new biology of ageing
-
Partridge L (2010). The new biology of ageing. Phil Trans R Soc B, 365:147-54.
-
(2010)
Phil Trans R Soc B
, vol.365
, pp. 147-154
-
-
Partridge, L.1
-
61
-
-
70349669095
-
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
-
Selman C, Tullet JMA, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson ICA, Schuster E, Batterham RL, Kozma SC, Thomas G, Carling D, Okkenhaug K, Thornton JM, Partridge L, Gems D, Withers DJ (2009). Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science, 326:140-4.
-
(2009)
Science
, vol.326
, pp. 140-144
-
-
Selman, C.1
Tullet, J.M.A.2
Wieser, D.3
Irvine, E.4
Lingard, S.J.5
Choudhury, A.I.6
Claret, M.7
Al-Qassab, H.8
Carmignac, D.9
Ramadani, F.10
Woods, A.11
Robinson, I.C.A.12
Schuster, E.13
Batterham, R.L.14
Kozma, S.C.15
Thomas, G.16
Carling, D.17
Okkenhaug, K.18
Thornton, J.M.19
Partridge, L.20
Gems, D.21
Withers, D.J.22
more..
-
62
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBß)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB III, Kaestner KH, Bartolomei MS, Shulman GI, and Birnbaum MJ (2001). Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBß). Science, 292:1728-31.
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw E.B, I.I.I.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
63
-
-
0035914388
-
Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho H, Thorvaldsen J, Chu Q, Feng F, Birnbaum M (2001). Akt1/PKBα is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem, 276:38349-52.
-
(2001)
J Biol Chem
, vol.276
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.2
Chu, Q.3
Feng, F.4
Birnbaum, M.5
-
64
-
-
85047693348
-
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBß
-
Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL, Coskran T, Black SC, Brees DJ, Wicks JR, McNeish JD, Coleman KG (2003). Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKBß. J Clin Invest, 112:197-208.
-
(2003)
J Clin Invest
, vol.112
, pp. 197-208
-
-
Garofalo, R.S.1
Orena, S.J.2
Rafidi, K.3
Torchia, A.J.4
Stock, J.L.5
Hildebrandt, A.L.6
Coskran, T.7
Black, S.C.8
Brees, D.J.9
Wicks, J.R.10
McNeish, J.D.11
Coleman, K.G.12
-
65
-
-
33744505375
-
Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1
-
Um SH, D'Alessio D, Thomas G (2006). Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1. Cell Metab, 3:393-402.
-
(2006)
Cell Metab
, vol.3
, pp. 393-402
-
-
Um, S.H.1
D'Alessio, D.2
Thomas, G.3
-
66
-
-
41649094265
-
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species
-
Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DEL, Thomas JH, Kaeberlein M, Kennedy BK (2008). Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. Genome Res, 18:564-70.
-
(2008)
Genome Res
, vol.18
, pp. 564-570
-
-
Smith, E.D.1
Tsuchiya, M.2
Fox, L.A.3
Dang, N.4
Hu, D.5
Kerr, E.O.6
Johnston, E.D.7
Tchao, B.N.8
Pak, D.N.9
Welton, K.L.10
Promislow, D.E.L.11
Thomas, J.H.12
Kaeberlein, M.13
Kennedy, B.K.14
-
67
-
-
67650944993
-
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
-
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle1 CM, Flurkey K, Nadon NC, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA (2009). Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature, 460:392-5.
-
(2009)
Nature
, vol.460
, pp. 392-395
-
-
Harrison, D.E.1
Strong, R.2
Sharp, Z.D.3
Nelson, J.F.4
Astle1, C.M.5
Flurkey, K.6
Nadon, N.C.7
Wilkinson, J.E.8
Frenkel, K.9
Carter, C.S.10
Pahor, M.11
Javors, M.A.12
Fernandez, E.13
Miller, R.A.14
-
68
-
-
84900042030
-
The role of TOR signaling in aging
-
In: Wolf NS, editor., Netherlands: Springer
-
Kaeberlein M, Shamieh LS (2010). The role of TOR signaling in aging. In: Wolf NS, editor. Comparative biology of aging. Netherlands: Springer, 147-61.
-
(2010)
Comparative biology of aging
, pp. 147-161
-
-
Kaeberlein, M.1
Shamieh, L.S2
-
69
-
-
77953014263
-
The role of mTOR signaling in controlling mammalian life span: What a fungicide teaches us about longevity.
-
Sharp ZD, Strong R (2010). The role of mTOR signaling in controlling mammalian life span: What a fungicide teaches us about longevity. J Gerontol A Biol Sci Med Sci, 65A:580-9.
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65 A
, pp. 580-589
-
-
Sharp, Z.D.1
Strong, R.2
-
70
-
-
0031558028
-
The IGF-I receptor in cell growth, transformation and apoptosis
-
Baserga R, Hongo A, Rubini M, Prisco M, Valentinis B (1997). The IGF-I receptor in cell growth, transformation and apoptosis. Biochim Biophys Acta Rev Cancer, 1332:F105-F126.
-
(1997)
Biochim Biophys Acta Rev Cancer
, vol.1332
, pp. F105-F126
-
-
Baserga, R.1
Hongo, A.2
Rubini, M.3
Prisco, M.4
Valentinis, B.5
-
71
-
-
36248934760
-
Macromolecule biosynthesis: a key function of sleep
-
Mackiewicz M, Shockley KR, Romer MA, Galante RJ, Zimmerman JE, Naidoo N, Baldwin DA, Jensen ST, Churchill GA, Pack AI (2007). Macromolecule biosynthesis: a key function of sleep. Physiol Genomics, 31:441-57.
-
(2007)
Physiol Genomics
, vol.31
, pp. 441-457
-
-
Mackiewicz, M.1
Shockley, K.R.2
Romer, M.A.3
Galante, R.J.4
Zimmerman, J.E.5
Naidoo, N.6
Baldwin, D.A.7
Jensen, S.T.8
Churchill, G.A.9
Pack, A.I.10
-
72
-
-
50249187869
-
Circadian oscillation of hippocampal MAPK activity and cAMP: implications for memory persistence
-
Eckel-Mahan KL, Phan T, Han S, Wang H, Chan GCK, Scheiner ZS, Storm DR (2008). Circadian oscillation of hippocampal MAPK activity and cAMP: implications for memory persistence. Nature Neurosci, 11:1074-82.
-
(2008)
Nature Neurosci
, vol.11
, pp. 1074-1082
-
-
Eckel-Mahan, K.L.1
Phan, T.2
Han, S.3
Wang, H.4
Chan, G.C.K.5
Scheiner, Z.S.6
Storm, D.R.7
-
73
-
-
45649084209
-
Photic regulation of the mTOR signaling pathway in the suprachiasmatic circadian clock
-
Cao R, Lee B, Cho HY, Saklayen S, Obrietan K (2008). Photic regulation of the mTOR signaling pathway in the suprachiasmatic circadian clock. Mol Cell Neurosci, 38:312-24.
-
(2008)
Mol Cell Neurosci
, vol.38
, pp. 312-324
-
-
Cao, R.1
Lee, B.2
Cho, H.Y.3
Saklayen, S.4
Obrietan, K.5
-
74
-
-
77951778497
-
Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock
-
Cao R, Li A, Cho HY, Lee B, Obrietan K (2010). Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock. J Neurosci, 30:6302-14.
-
(2010)
J Neurosci
, vol.30
, pp. 6302-6314
-
-
Cao, R.1
Li, A.2
Cho, H.Y.3
Lee, B.4
Obrietan, K.5
-
75
-
-
34548614737
-
Loss of pregnancy-associated plasma protein A extends lifespan in mice
-
Conover CA, Bale LK (2007). Loss of pregnancy-associated plasma protein A extends lifespan in mice. Aging Cell, 6:727-29.
-
(2007)
Aging Cell
, vol.6
, pp. 727-729
-
-
Conover, C.A.1
Bale, L.K.2
-
76
-
-
0032981399
-
The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A
-
Lawrence JB, Oxvig C, Overgaard MT, Sottrup-Jensen L, Gleich GJ, Hays LG, Yates JRIII, Conover CA (1999). The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc. Natl. Acad. Sci. USA, 96:3149-53.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3149-3153
-
-
Lawrence, J.B.1
Oxvig, C.2
Overgaard, M.T.3
Sottrup-Jensen, L.4
Gleich, G.J.5
Hays, L.G.6
Yates III, J.R.7
Conover, C.A.8
-
77
-
-
0037006795
-
Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus
-
Akhtar RA, Reddy AB, Maywood ES, Clayton JD, King VM, Smith AG, Gant TW, Hastings MH, Kyriacou CP (2002). Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol, 12:540-50.
-
(2002)
Curr Biol
, vol.12
, pp. 540-550
-
-
Akhtar, R.A.1
Reddy, A.B.2
Maywood, E.S.3
Clayton, J.D.4
King, V.M.5
Smith, A.G.6
Gant, T.W.7
Hastings, M.H.8
Kyriacou, C.P.9
-
78
-
-
0033081267
-
Evidence supporting a direct suppressive effect of growth hormone on serum IGFBP-1levels. Experimental studies in normal, obese and GH-deficient adults
-
Norrelund H, Fisker S, Vahl N, Børglum J, Richelsen B, Christiansen JS, Jørgensen JOL (1999). Evidence supporting a direct suppressive effect of growth hormone on serum IGFBP-1levels. Experimental studies in normal, obese and GH-deficient adults. Growth Horm IGF Res, 9:52-60.
-
(1999)
Growth Horm IGF Res
, vol.9
, pp. 52-60
-
-
Norrelund, H.1
Fisker, S.2
Vahl, N.3
Børglum, J.4
Richelsen, B.5
Christiansen, J.S.6
Jørgensen, J.O.L.7
-
79
-
-
32044435126
-
Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways
-
Levine AJ, Feng Z, Mak TM, You H, Jin S (2006). Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Genes Dev, 20:267-75.
-
(2006)
Genes Dev
, vol.20
, pp. 267-275
-
-
Levine, A.J.1
Feng, Z.2
Mak, T.M.3
You, H.4
Jin, S.5
-
80
-
-
0034788985
-
The IGF system and breast cancer
-
Sachdev D, Yee D (2001). The IGF system and breast cancer. Endocr Rel Cancer, 8:197-209.
-
(2001)
Endocr Rel Cancer
, vol.8
, pp. 197-209
-
-
Sachdev, D.1
Yee, D.2
-
81
-
-
18144388714
-
Induction of IGFBP-1 expression by amino acid deprivation of HepG2 human hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3'UTR
-
Averous J, Maurin AC, Bruhat A, Jousse C, Arliguie C, Fafournoux P (2005). Induction of IGFBP-1 expression by amino acid deprivation of HepG2 human hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3'UTR. FEBS Lettr, 579:2609-2614.
-
(2005)
FEBS Lettr
, vol.579
, pp. 2609-2614
-
-
Averous, J.1
Maurin, A.C.2
Bruhat, A.3
Jousse, C.4
Arliguie, C.5
Fafournoux, P.6
-
82
-
-
33750319702
-
A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression
-
Finlay D, Ruiz-Alcaraz AJ, Lipina C, Perrier S, Sutherland C (2006). A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression. J Mol Endocrinol, 37:227-37.
-
(2006)
J Mol Endocrinol
, vol.37
, pp. 227-237
-
-
Finlay, D.1
Ruiz-Alcaraz, A.J.2
Lipina, C.3
Perrier, S.4
Sutherland, C.5
-
83
-
-
18244379033
-
Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice
-
Sharp ZD, Bartke A (2005). Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice. J Gerontol Ser A Biol Sci Med Sci, 60:293-300.
-
(2005)
J Gerontol Ser A Biol Sci Med Sci
, vol.60
, pp. 293-300
-
-
Sharp, Z.D.1
Bartke, A.2
-
84
-
-
51349161232
-
Transgenic mice overexpressing GH exhibit hepatic upregulation of GH-signaling mediators involved in cell proliferation
-
Miquet JG, Gonzalez L, Matos MN, Hansen CE, Louis A, Bartke A, Turyn D, Sotelo AI (2008). Transgenic mice overexpressing GH exhibit hepatic upregulation of GH-signaling mediators involved in cell proliferation. J Endocrinol, 198:317-30.
-
(2008)
J Endocrinol
, vol.198
, pp. 317-330
-
-
Miquet, J.G.1
Gonzalez, L.2
Matos, M.N.3
Hansen, C.E.4
Louis, A.5
Bartke, A.6
Turyn, D.7
Sotelo, A.I.8
-
85
-
-
34447578825
-
The rapid activation of protein synthesis by growth hormone requires signaling through mTOR
-
Hayashi AA, Proud CG (2007). The rapid activation of protein synthesis by growth hormone requires signaling through mTOR. Am J Physiol Endocrinol Metab, 292:E1647-E1655.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, pp. E1647-E1655
-
-
Hayashi, A.A.1
Proud, C.G.2
-
86
-
-
0025597112
-
Rates of cerebral protein synthesis are linked to slow wave sleep in the rat
-
Ramm P, Smith CT (1990). Rates of cerebral protein synthesis are linked to slow wave sleep in the rat. Physiol Behav, 48:749-53.
-
(1990)
Physiol Behav
, vol.48
, pp. 749-753
-
-
Ramm, P.1
Smith, C.T.2
-
87
-
-
0347948474
-
Extensive and divergent effects of sleep and wakefulness on brain gene expression
-
Cirelli C, Gutierrez CM, Tononi G (2004). Extensive and divergent effects of sleep and wakefulness on brain gene expression. Neuron, 41:35-43.
-
(2004)
Neuron
, vol.41
, pp. 35-43
-
-
Cirelli, C.1
Gutierrez, C.M.2
Tononi, G.3
-
88
-
-
67651097622
-
The genetic and molecular regulation of sleep: from fruit flies to humans
-
Cirelli C (2009). The genetic and molecular regulation of sleep: from fruit flies to humans. Nature Rev Neurosci, 10:549-60.
-
(2009)
Nature Rev Neurosci
, vol.10
, pp. 549-560
-
-
Cirelli, C.1
-
89
-
-
58149511938
-
Salubrinal, an inhibitor of protein synthesis, promotes deep slow wave sleep
-
Methippara MM, Bashir T, Kumar S, Alam DN, Szymusiak R, McGinty D (2009). Salubrinal, an inhibitor of protein synthesis, promotes deep slow wave sleep. Am J Physiol Regul Integr Comp Physiol, 296:R178-R184.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.296
, pp. R178-R184
-
-
Methippara, M.M.1
Bashir, T.2
Kumar, S.3
Alam, D.N.4
Szymusiak, R.5
McGinty, D.6
-
90
-
-
33847233874
-
Pregnancy-associated plasma protein-A (PAPP-A): A local regulator of IGF bioavailability through cleavage of IGFBPs
-
Boldt HB, Conover CA (2007). Pregnancy-associated plasma protein-A (PAPP-A): A local regulator of IGF bioavailability through cleavage of IGFBPs. Growth Horm IGF Res, 17:10-18.
-
(2007)
Growth Horm IGF Res
, vol.17
, pp. 10-18
-
-
Boldt, H.B.1
Conover, C.A.2
-
91
-
-
77953015038
-
Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-A.
-
Conover CA, Bale LK, Mader JR, Mason MA, Keenan KP, Marler RJ (2010). Longevity and age-related pathology of mice deficient in pregnancy-associated plasma protein-A. J Gerontol A Biol Sci Med Sci, 65A:590-599.
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65 A
, pp. 590-599
-
-
Conover, C.A.1
Bale, L.K.2
Mader, J.R.3
Mason, M.A.4
Keenan, K.P.5
Marler, R.J.6
-
92
-
-
0026494802
-
Somatostatin analog induces insulin- like growth factor binding protein-1 (IGFBP-1) expression in human hepatoma cells
-
Ren SG, Ezzat S, Melmed S, Braunstein GD (1992). Somatostatin analog induces insulin- like growth factor binding protein-1 (IGFBP-1) expression in human hepatoma cells. Endocrinol, 131:2479-81.
-
(1992)
Endocrinol
, vol.131
, pp. 2479-2481
-
-
Ren, S.G.1
Ezzat, S.2
Melmed, S.3
Braunstein, G.D.4
-
93
-
-
43149103684
-
PP2A regulates the pro-apoptotic activity of FOXO1
-
Yan L, Lavin VA, Moser LR, Cui Q, Kanies C, Yang E (2008). PP2A regulates the pro-apoptotic activity of FOXO1. J Biol Chem, 283:7411-20.
-
(2008)
J Biol Chem
, vol.283
, pp. 7411-7420
-
-
Yan, L.1
Lavin, V.A.2
Moser, L.R.3
Cui, Q.4
Kanies, C.5
Yang, E.6
-
94
-
-
57749172240
-
Dependence of dexamethasone induced Akt/FOXO1signaling, upregulation of MAFbx, and protein catabolism upon the glucocorticoid receptor
-
Zhao W, Qin W, Pan J, Wu Y, Bauman WA, Cardozo C (2009). Dependence of dexamethasone induced Akt/FOXO1signaling, upregulation of MAFbx, and protein catabolism upon the glucocorticoid receptor. Biochem Biophys Res Comm, 378:668-72.
-
(2009)
Biochem Biophys Res Comm
, vol.378
, pp. 668-672
-
-
Zhao, W.1
Qin, W.2
Pan, J.3
Wu, Y.4
Bauman, W.A.5
Cardozo, C.6
-
95
-
-
73949116424
-
Time course expression of Foxo transcription factors in skeletal muscle following corticosteroid administration
-
Cho JE, Fournier M, Da X, Lewis MI (2010). Time course expression of Foxo transcription factors in skeletal muscle following corticosteroid administration. J Appl Physiol, 108:137-45.
-
(2010)
J Appl Physiol
, vol.108
, pp. 137-145
-
-
Cho, J.E.1
Fournier, M.2
Da, X.3
Lewis, M.I.4
-
96
-
-
56049123409
-
The glucocorticoid receptor and FOXO1 synergistically activate the skeletalmuscle atrophy-associated MuRF1 gene
-
Waddell DS, Baehr LM, van den Brandt J, Johnsen SA, Reichardt HM, Furlow JD, Bodine SC (2008). The glucocorticoid receptor and FOXO1 synergistically activate the skeletalmuscle atrophy-associated MuRF1 gene. Am J Physiol Endocrinol Metab, 295:E785-E797.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. E785-E797
-
-
Waddell, D.S.1
Baehr, L.M.2
van den Brandt, J.3
Johnsen, S.A.4
Reichardt, H.M.5
Furlow, J.D.6
Bodine, S.C.7
-
97
-
-
0028127201
-
Glucocorticoids and insulin regulate expression of the human gene for insulin-like growth factor-binding protein-1 through proximal promoter elements
-
Suwanichkul A, Allander SV, Morris SL, Powell DR (1994). Glucocorticoids and insulin regulate expression of the human gene for insulin-like growth factor-binding protein-1 through proximal promoter elements. J Biol Chem, 269:30835-41.
-
(1994)
J Biol Chem
, vol.269
, pp. 30835-30841
-
-
Suwanichkul, A.1
Allander, S.V.2
Morris, S.L.3
Powell, D.R.4
-
98
-
-
0028927658
-
Regulation of insulin-like growth factor binding protein-I during the 24-hour metabolic clock and in response to hypoinsulinemia induced by fasting and sandostatin in normal women
-
Holden JP, Butzow TL, Laughlin GA, Ho M, Morales AJ, Yen SC (1995). Regulation of insulin-like growth factor binding protein-I during the 24-hour metabolic clock and in response to hypoinsulinemia induced by fasting and sandostatin in normal women. J Soc Gynecol Inv, 2:38-44.
-
(1995)
J Soc Gynecol Inv
, vol.2
, pp. 38-44
-
-
Holden, J.P.1
Butzow, T.L.2
Laughlin, G.A.3
Ho, M.4
Morales, A.J.5
Yen, S.C.6
-
99
-
-
0032982610
-
Correlation between cortisol and insulin-like growth factor-binding proteins (IGFBPs) under physiological conditions in children
-
Martinelli CE Jr, Yateman ME, Cotterill AM, Moreira AC, Camacho-Hubner C (1999). Correlation between cortisol and insulin-like growth factor-binding proteins (IGFBPs) under physiological conditions in children. Clin Endocrinol, 50:767-74.
-
(1999)
Clin Endocrinol
, vol.50
, pp. 767-774
-
-
Martinelli C.E, Jr.1
Yateman, M.E.2
Cotterill, A.M.3
Moreira, A.C.4
Camacho-Hubner, C.5
-
100
-
-
0030958227
-
Somatostatin: the neuroendocrine story
-
Gillies G (1997). Somatostatin: the neuroendocrine story. Trends Pharmacol Sci, 18:87-95.
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 87-95
-
-
Gillies, G.1
-
101
-
-
0029035254
-
Growth hormone-releasing hormone mediates feeding-specific feedback to the suprachiasmatic circadian clock
-
Vaccarino FJ, Sovran P, Baird JP, Ralph MR (1995). Growth hormone-releasing hormone mediates feeding-specific feedback to the suprachiasmatic circadian clock. Peptides, 16:595-8.
-
(1995)
Peptides
, vol.16
, pp. 595-598
-
-
Vaccarino, F.J.1
Sovran, P.2
Baird, J.P.3
Ralph, M.R.4
-
102
-
-
0034730660
-
Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin: the role of winged helix/forkhead proteins
-
Hall RK, Yamasaki T, Kucera T, Waltner-Law M, O'Brien R, Granner DK (2000). Regulation of phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein-1 gene expression by insulin: the role of winged helix/forkhead proteins. J Biol Chem, 275:30169-75.
-
(2000)
J Biol Chem
, vol.275
, pp. 30169-30175
-
-
Hall, R.K.1
Yamasaki, T.2
Kucera, T.3
Waltner-Law, M.4
O'Brien, R.5
Granner, D.K.6
-
103
-
-
33846295218
-
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
-
Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA (2007). FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell, 128:309-23.
-
(2007)
Cell
, vol.128
, pp. 309-323
-
-
Paik, J.H.1
Kollipara, R.2
Chu, G.3
Ji, H.4
Xiao, Y.5
Ding, Z.6
Miao, L.7
Tothova, Z.8
Horner, J.W.9
Carrasco, D.R.10
Jiang, S.11
Gilliland, D.G.12
Chin, L.13
Wong, W.H.14
Castrillon, D.H.15
DePinho, R.A.16
-
104
-
-
33644821240
-
Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol
-
Conover CA, Bale LK, Harrington SC, Resch ZT, Overgaard MT, Oxvig C (2006). Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by resveratrol. Am J Physiol Cell Physiol, 290:C183-C188.
-
(2006)
Am J Physiol Cell Physiol
, vol.290
, pp. C183-C188
-
-
Conover, C.A.1
Bale, L.K.2
Harrington, S.C.3
Resch, Z.T.4
Overgaard, M.T.5
Oxvig, C.6
-
105
-
-
1842475551
-
Protein kinase B-α inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors
-
Kwon HS, Huang B, Unterman TG, Harris RA (2004). Protein kinase B-α inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors. Diabetes, 53:899-910.
-
(2004)
Diabetes
, vol.53
, pp. 899-910
-
-
Kwon, H.S.1
Huang, B.2
Unterman, T.G.3
Harris, R.A.4
-
106
-
-
2942726155
-
The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation
-
van der Heide LP, Hoekman MFM, Smidt MP (2004). The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem J, 380:297-309.
-
(2004)
Biochem J
, vol.380
, pp. 297-309
-
-
van der Heide, L.P.1
Hoekman, M.F.M.2
Smidt, M.P.3
-
107
-
-
24944436224
-
Insulin response sequence-dependent and -independent mechanisms mediate effects of insulin on glucocorticoid-stimulated insulin-like growth factor binding protein-1 promoter activity
-
Gan L, Pan H, Unterman TG (2005). Insulin response sequence-dependent and -independent mechanisms mediate effects of insulin on glucocorticoid-stimulated insulin-like growth factor binding protein-1 promoter activity. Endocrinol, 146:4274-80.
-
(2005)
Endocrinol
, vol.146
, pp. 4274-4280
-
-
Gan, L.1
Pan, H.2
Unterman, T.G.3
-
108
-
-
3142734385
-
Additive regulation of hepatic gene expression by dwarfism and caloric restriction
-
Tsuchiya T, Dhahbi JM, Cui X, Mote P.L, Bartke A, Spindler SR (2004). Additive regulation of hepatic gene expression by dwarfism and caloric restriction. Physiol Genomics, 17:307-15.
-
(2004)
Physiol Genomics
, vol.17
, pp. 307-315
-
-
Tsuchiya, T.1
Dhahbi, J.M.2
Cui, X.3
Mote, P.L.4
Bartke, A.5
Spindler, S.R.6
-
109
-
-
70349142240
-
Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbα
-
Wu N, Yin L, Hanniman EA, Joshi S, Lazar MA (2009). Negative feedback maintenance of heme homeostasis by its receptor, Rev-erbα. Genes Dev, 23:2201-9.
-
(2009)
Genes Dev
, vol.23
, pp. 2201-2209
-
-
Wu, N.1
Yin, L.2
Hanniman, E.A.3
Joshi, S.4
Lazar, M.A.5
-
110
-
-
23944476164
-
Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1α
-
Handschin C, Lin J, Rhee J, Peyer AK, Chin S, Wu PH, Meyer UA, Spiegelman BM (2005). Nutritional regulation of hepatic heme biosynthesis and porphyria through PGC-1α. Cell, 122: 505-15.
-
(2005)
Cell
, vol.122
, pp. 505-515
-
-
Handschin, C.1
Lin, J.2
Rhee, J.3
Peyer, A.K.4
Chin, S.5
Wu, P.H.6
Meyer, U.A.7
Spiegelman, B.M.8
-
111
-
-
33745329809
-
The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification
-
Gachon F, Olela FF, Schaad O, Descombes P, Schibler U (2006). The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification. Cell Metab, 4:25-36.
-
(2006)
Cell Metab
, vol.4
, pp. 25-36
-
-
Gachon, F.1
Olela, F.F.2
Schaad, O.3
Descombes, P.4
Schibler, U.5
-
112
-
-
41849086320
-
FOXO-binding partners: it takes two to tango
-
Van der Vos, KE, Coffer PJ (2008). FOXO-binding partners: it takes two to tango. Oncogene, 27:2289-99.
-
(2008)
Oncogene
, vol.27
, pp. 2289-2299
-
-
Van der Vos, K.E.1
Coffer, P.J.2
-
113
-
-
0023829632
-
Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects
-
Polonski KS, Given BD, Van Cauter E (1998). Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. J Clin Invest, 81:442-8.
-
(1998)
J Clin Invest
, vol.81
, pp. 442-448
-
-
Polonski, K.S.1
Given, B.D.2
Van Cauter, E.3
-
114
-
-
65549122452
-
Insulin sensitivity as a key mediator of growth hormone actions on longevity.
-
Masternak MM, Panici JA, Bonkowski MS, Hughes LF, Bartke A (2009). Insulin sensitivity as a key mediator of growth hormone actions on longevity. J Gerontol A Biol Sci Med Sci, 64A:516-21.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64 A
, pp. 516-521
-
-
Masternak, M.M.1
Panici, J.A.2
Bonkowski, M.S.3
Hughes, L.F.4
Bartke, A.5
-
115
-
-
57349159512
-
The evolutionary ecology of body size with special reference to allometry and survivorship
-
In: Samaras T, editor, New York: Nova Science Publishers
-
Rollo CD (2007). The evolutionary ecology of body size with special reference to allometry and survivorship. In: Samaras T, editor. Human body size and the laws of scaling. New York: Nova Science Publishers, 213-34.
-
(2007)
Human body size and the laws of scaling
, pp. 213-234
-
-
Rollo, C.D1
-
116
-
-
32444433450
-
Hypoxia-induced energy stress regulates mRNA translation and cell growth
-
Liu L, Cash TP, Jones RG, Keith B, Thompson CB, Simon MC (2006). Hypoxia-induced energy stress regulates mRNA translation and cell growth. Mol. Cell, 21:521-31.
-
(2006)
Mol. Cell
, vol.21
, pp. 521-531
-
-
Liu, L.1
Cash, T.P.2
Jones, R.G.3
Keith, B.4
Thompson, C.B.5
Simon, M.C.6
-
117
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, Auwerx J (2009). AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature, 458:1056-60.
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
118
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C
-
Greer EL, Brunet A (2009). Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell, 8:113-27.
-
(2009)
elegans. Aging Cell
, vol.8
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
119
-
-
33644749330
-
Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells
-
Kukidome D, Nishikawa T, Sonoda K, Imoto K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Matsumura T, Araki E (2006). Activation of AMP-activated protein kinase reduces hyperglycemia-induced mitochondrial reactive oxygen species production and promotes mitochondrial biogenesis in human umbilical vein endothelial cells. Diabetes, 55:120-127.
-
(2006)
Diabetes
, vol.55
, pp. 120-127
-
-
Kukidome, D.1
Nishikawa, T.2
Sonoda, K.3
Imoto, K.4
Fujisawa, K.5
Yano, M.6
Motoshima, H.7
Taguchi, T.8
Matsumura, T.9
Araki, E.10
-
120
-
-
65549118773
-
Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1
-
Nakahata Y, Sahar S, Astarita G, Kaluzova M, Sassone-Corsi P (2009). Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1. Science, 324:654-57.
-
(2009)
Science
, vol.324
, pp. 654-657
-
-
Nakahata, Y.1
Sahar, S.2
Astarita, G.3
Kaluzova, M.4
Sassone-Corsi, P.5
-
121
-
-
58549115733
-
Energy responsive timekeeping
-
Bechtold DA (2009).Energy responsive timekeeping. Genetics, 87:447-58.
-
(2009)
Genetics
, vol.87
, pp. 447-458
-
-
Bechtold, D.A1
-
122
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA (2006). Resveratrol improves health and survival of mice on a high-calorie diet. Nature, 444:337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
de Cabo, R.26
Sinclair, D.A.27
more..
-
123
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J (2006). Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell, 127:1109-22.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
124
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN (2006). TOR signaling in growth and metabolism. Cell, 124:471-84.
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
125
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma XM, Blenis J (2009). Molecular mechanisms of mTOR-mediated translational control. Nature Rev Mol Cell Biol, 10:307-18.
-
(2009)
Nature Rev Mol Cell Biol
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
126
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, Turk BE, Shaw RJ (2008). AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol Cell, 30:214-26.
-
(2008)
Mol Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
Mihaylova, M.M.4
Mery, A.5
Vasquez, D.S.6
Turk, B.E.7
Shaw, R.J.8
-
127
-
-
34547127625
-
Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iε (CKIε)-dependent degradation of clock protein mPer2
-
Um JH, Yang S, Yamazaki S, Kang H, Viollet B, Foretz M, Chung JH (2007). Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iε (CKIε)-dependent degradation of clock protein mPer2. J Biol Chem, 282:20794-8.
-
(2007)
J Biol Chem
, vol.282
, pp. 20794-20798
-
-
Um, J.H.1
Yang, S.2
Yamazaki, S.3
Kang, H.4
Viollet, B.5
Foretz, M.6
Chung, J.H.7
-
128
-
-
70350128135
-
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
-
Lamia KA, Sachdeva UM, DiTacchio L, Williams EC, Alvarez JG, Egan DF, Vasquez DS, Juguilon H, Panda S, Shaw RJ, Thompson CB, Evans RM (2009). AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation. Science, 326:437-40.
-
(2009)
Science
, vol.326
, pp. 437-440
-
-
Lamia, K.A.1
Sachdeva, U.M.2
DiTacchio, L.3
Williams, E.C.4
Alvarez, J.G.5
Egan, D.F.6
Vasquez, D.S.7
Juguilon, H.8
Panda, S.9
Shaw, R.J.10
Thompson, C.B.11
Evans, R.M.12
-
130
-
-
57049100909
-
Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle
-
Vieira E, Nilsson EC, Nerstedt A, Ormestad M, Long YC, Garcia-Roves PM, Zierath JR, Mahlapuu M (2008). Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle. Am J Physiol Endocrinol Metab, 295:E1032-E1037.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. E1032-E1037
-
-
Vieira, E.1
Nilsson, E.C.2
Nerstedt, A.3
Ormestad, M.4
Long, Y.C.5
Garcia-Roves, P.M.6
Zierath, J.R.7
Mahlapuu, M.8
-
131
-
-
70349633673
-
Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin
-
Li XN, Song J, Zhang L, LeMaire SA, Hou X, Zhang C, Coselli JS, Chen L, Wang XL, Zhang Y, Coselli JS, Chen L, Wang XL, Zhang Y, Shen YH (2009). Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin. Diabetes, 58:2246-57.
-
(2009)
Diabetes
, vol.58
, pp. 2246-2257
-
-
Li, X.N.1
Song, J.2
Zhang, L.3
LeMaire, S.A.4
Hou, X.5
Zhang, C.6
Coselli, J.S.7
Chen, L.8
Wang, X.L.9
Zhang, Y.10
Coselli, J.S.11
Chen, L.12
Wang, X.L.13
Zhang, Y.14
Shen, Y.H.15
-
132
-
-
77950989801
-
AMPKα2 deletion causes aberrant expression and activation of AD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes
-
Wang S, Zhang M, Liang B, Xu J, Xie Z, Liu C, Viollet B, Yan D, Zou MH (2010). AMPKα2 deletion causes aberrant expression and activation of AD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes. Cir Res, 106:1117-28.
-
(2010)
Cir Res
, vol.106
, pp. 1117-1128
-
-
Wang, S.1
Zhang, M.2
Liang, B.3
Xu, J.4
Xie, Z.5
Liu, C.6
Viollet, B.7
Yan, D.8
Zou, M.H.9
-
133
-
-
44249094901
-
cAMP-dependent signaling as a core component of the mammalian circadian pacemaker.
-
O'Neill JS, Maywood ES, Chesha JE, Takahashi JS, Hastings MH (2008). cAMP-dependent signaling as a core component of the mammalian circadian pacemaker. Science 320:949-53.
-
(2008)
Science
, vol.320
, pp. 949-953
-
-
O'Neill, J.S.1
Maywood, E.S.2
Chesha, J.E.3
Takahashi, J.S.4
Hastings, M.H5
-
134
-
-
34848861463
-
The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor
-
MP, Gygi SP, Brunet A (2007). The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem, 282:30107-19.
-
(2007)
J Biol Chem
, vol.282
, pp. 30107-30119
-
-
Gygi, S.P.1
Brunet, A.2
-
135
-
-
70349799010
-
The cell cycle is a redox cycle: Linking phase-specific targets to cell fate
-
Burhans WC, Heintz NH (2009). The cell cycle is a redox cycle: Linking phase-specific targets to cell fate. Free Radical Biol Med, 47:1282-1293.
-
(2009)
Free Radical Biol Med
, vol.47
, pp. 1282-1293
-
-
Burhans, W.C.1
Heintz, N.H.2
-
136
-
-
72749089361
-
Working around the clock: circadian rhythms and skeletal muscle
-
Zhang X, Dube TJ, Esser KA (2009). Working around the clock: circadian rhythms and skeletal muscle. J Appl Physiol, 107:1647-54.
-
(2009)
J Appl Physiol
, vol.107
, pp. 1647-1654
-
-
Zhang, X.1
Dube, T.J.2
Esser, K.A.3
-
137
-
-
0037136563
-
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
-
Kops GJ, Dansen TB, Polderman PE, Saarloos I, Wirtz KW, Coffer PJ, Huang TT, Bos JL, Medema RH, Burgering BM (2002). Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature, 419:316-21.
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
Dansen, T.B.2
Polderman, P.E.3
Saarloos, I.4
Wirtz, K.W.5
Coffer, P.J.6
Huang, T.T.7
Bos, J.L.8
Medema, R.H.9
Burgering, B.M.10
-
138
-
-
10644282295
-
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C
-
Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R (2004). The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev, 18:3004-3009.
-
(2004)
elegans. Genes Dev
, vol.18
, pp. 3004-3009
-
-
Apfeld, J.1
O'Connor, G.2
McDonagh, T.3
DiStefano, P.S.4
Curtis, R.5
-
139
-
-
33847338780
-
Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice
-
Selman C, Kerrison ND, Cooray A, Piper MDW, Lingard SJ, Barton RH, Schuster EF, Blanc E, Gems D, Nicholson JK, Thornton JM, Partridge L, Withers DJ (2006). Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. Physiol. Genomics, 27:187-200.
-
(2006)
Physiol. Genomics
, vol.27
, pp. 187-200
-
-
Selman, C.1
Kerrison, N.D.2
Cooray, A.3
Piper, M.D.W.4
Lingard, S.J.5
Barton, R.H.6
Schuster, E.F.7
Blanc, E.8
Gems, D.9
Nicholson, J.K.10
Thornton, J.M.11
Partridge, L.12
Withers, D.J.13
-
141
-
-
34748850786
-
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
-
Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M (2007). Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab, 6:280-93.
-
(2007)
Cell Metab
, vol.6
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
142
-
-
65549100013
-
Cytochrome P450 and the biological clock in mammals
-
Froy O (2009). Cytochrome P450 and the biological clock in mammals. Curr Drug Metab, 10:104-15.
-
(2009)
Curr Drug Metab
, vol.10
, pp. 104-115
-
-
Froy, O.1
-
143
-
-
0035923746
-
Circadian regulation of gene expression systems in the Drosophila head
-
Claridge-Chang A, Wijinen H, Naef F, Boothroyd C, Rajewsky N, Young MW (2001). Circadian regulation of gene expression systems in the Drosophila head. Neuron, 32:657-671.
-
(2001)
Neuron
, vol.32
, pp. 657-671
-
-
Claridge-Chang, A.1
Wijinen, H.2
Naef, F.3
Boothroyd, C.4
Rajewsky, N.5
Young, M.W.6
-
144
-
-
34248207609
-
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO
-
Gershman B, Puig O, Hang L, Peitzsch RM, Tatar M, Garofalo RS (2007). High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiol Genomics, 29:24-34.
-
(2007)
Physiol Genomics
, vol.29
, pp. 24-34
-
-
Gershman, B.1
Puig, O.2
Hang, L.3
Peitzsch, R.M.4
Tatar, M.5
Garofalo, R.S.6
-
145
-
-
0034680839
-
Regulation of glucose-6-phosphatase gene expression by protein kinase Bα and the forkhead transcription factor FKHR: Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity
-
Schmoll D, Walker KS, Alessi DR, Grempler R, Burchell A, Guo S, Walther R, Unterman TG (2007). Regulation of glucose-6-phosphatase gene expression by protein kinase Bα and the forkhead transcription factor FKHR: Evidence for insulin response unit-dependent and -independent effects of insulin on promoter activity. J Biol Chem, 275:36324-33.
-
(2007)
J Biol Chem
, vol.275
, pp. 36324-36333
-
-
Schmoll, D.1
Walker, K.S.2
Alessi, D.R.3
Grempler, R.4
Burchell, A.5
Guo, S.6
Walther, R.7
Unterman, T.G.8
-
146
-
-
33744515637
-
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic and lipogenic gene expression
-
Zhang W, Patil S, Chauhan B, Guo S, Powell DR, Le J, Klotsas A, Matika R, Xiao X, Franks R, Heidenreich KA, Sajan MP, Farese RV, Stolz DB, Tso P, Koo SH, Montminy M, Unterman TG (2006). FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic and lipogenic gene expression. J Biol Chem, 281:10105-7.
-
(2006)
J Biol Chem
, vol.281
, pp. 10105-10107
-
-
Zhang, W.1
Patil, S.2
Chauhan, B.3
Guo, S.4
Powell, D.R.5
Le, J.6
Klotsas, A.7
Matika, R.8
Xiao, X.9
Franks, R.10
Heidenreich, K.A.11
Sajan, M.P.12
Farese, R.V.13
Stolz, D.B.14
Tso, P.15
Koo, S.H.16
Montminy, M.17
Unterman, T.G.18
-
147
-
-
33750719644
-
SCN outputs and the hypothalamic balance of life
-
Kalsbeek A, Palm IF, La Fleur SE, Scheer FAJL, Perreau-Lenz S, Ruiter M, Kreier F, Cailotto C, Buijs RM (2006). SCN outputs and the hypothalamic balance of life. J Biol Rhythms, 21:458-69.
-
(2006)
J Biol Rhythms
, vol.21
, pp. 458-469
-
-
Kalsbeek, A.1
Palm, I.F.2
La Fleur, S.E.3
Scheer, F.A.J.L.4
Perreau-Lenz, S.5
Ruiter, M.6
Kreier, F.7
Cailotto, C.8
Buijs, R.M.9
-
148
-
-
77649138576
-
Circadian rhythms and metabolic syndrome: from experimental genetics to human disease
-
Maury E, Ramsey KM, Bass J (2010). Circadian rhythms and metabolic syndrome: from experimental genetics to human disease. Circ Res, 106:447-62.
-
(2010)
Circ Res
, vol.106
, pp. 447-462
-
-
Maury, E.1
Ramsey, K.M.2
Bass, J.3
-
149
-
-
0019125454
-
The circadian change of gluconeogenesis in the liver in vivo in fed rats
-
Kida K, Nishio T, Yokozawa T, Nagai K, Matsuda H, Nakagawa H (1980). The circadian change of gluconeogenesis in the liver in vivo in fed rats. J Biochem, 88:1009-13.
-
(1980)
J Biochem
, vol.88
, pp. 1009-1013
-
-
Kida, K.1
Nishio, T.2
Yokozawa, T.3
Nagai, K.4
Matsuda, H.5
Nakagawa, H.6
-
150
-
-
0004188694
-
Central Regulation of Energy Metabolism With Special Reference to Circadian Rhythm
-
Editors, CRC Press, Boca Raton, FL: CRC Press
-
Nagai K, Nakagawa H Editors. Central Regulation of Energy Metabolism With Special Reference to Circadian Rhythm. CRC Press, Boca Raton, FL: CRC Press; 1992.
-
(1992)
-
-
Nagai, K.1
Nakagawa, H.2
-
151
-
-
34249275727
-
Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
-
Liu C, Li S, Liu T, Borjigin J, Lin JD (2007). Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism. Nature, 447:477-81.
-
(2007)
Nature
, vol.447
, pp. 477-481
-
-
Liu, C.1
Li, S.2
Liu, T.3
Borjigin, J.4
Lin, J.D.5
-
152
-
-
54449085416
-
Physiological significance of a peripheral tissue circadian clock
-
Lamia KA, Storch KF, Weitz CJ (2008). Physiological significance of a peripheral tissue circadian clock. Proc. Natl. Acad. Sci. USA, 105:15172-7.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15172-15177
-
-
Lamia, K.A.1
Storch, K.F.2
Weitz, C.J.3
-
153
-
-
0034992684
-
A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus
-
La Fleur SE, Kalsbeek A, Wortel J, Fekkes ML, Buijs RM (2001). A daily rhythm in glucose tolerance: a role for the suprachiasmatic nucleus. Diabetes, 50:1237-43.
-
(2001)
Diabetes
, vol.50
, pp. 1237-1243
-
-
La Fleur, S.E.1
Kalsbeek, A.2
Wortel, J.3
Fekkes, M.L.4
Buijs, R.M.5
-
154
-
-
14044264801
-
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis.
-
Rudic RD, McNamara P, Curtis AM, Boston RC, Panda S, Hogenesch JB, FitzGerald GA (2004). BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. PLoS Biol, 2(11): e377.
-
(2004)
PLoS Biol
, vol.2
, Issue.11
-
-
Rudic, R.D.1
McNamara, P.2
Curtis, A.M.3
Boston, R.C.4
Panda, S.5
Hogenesch, J.B.6
FitzGerald, G.A.7
-
155
-
-
20844461135
-
Obesity and metabolic syndrome in circadian Clock mutant mice
-
Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDearmon E, Laposky A, Losee-Olson S, Easton A, Jensen DR, Eckel RH, Takahashi JS, Bass J (2005). Obesity and metabolic syndrome in circadian Clock mutant mice. Science, 308:1043-5.
-
(2005)
Science
, vol.308
, pp. 1043-1045
-
-
Turek, F.W.1
Joshu, C.2
Kohsaka, A.3
Lin, E.4
Ivanova, G.5
McDearmon, E.6
Laposky, A.7
Losee-Olson, S.8
Easton, A.9
Jensen, D.R.10
Eckel, R.H.11
Takahashi, J.S.12
Bass, J.13
-
156
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon JC, Puigserver P, Chen G, Donovan J, Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, Newgard CB, Spiegelman BM (2001). Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature, 413:131-8.
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
157
-
-
70350447953
-
Glucocorticoid regulation of the circadian clock modulates glucose homeostasis
-
So AY, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ (2009). Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. Proc Natl Acad Sci USA, 106:17582-7.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 17582-17587
-
-
So, A.Y.1
Bernal, T.U.2
Pillsbury, M.L.3
Yamamoto, K.R.4
Feldman, B.J.5
-
158
-
-
29344452934
-
Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice
-
Oishi K, Atsumi G, Sugiyama S, Kodomari I, Kasamatsu M, Machida K, Ishida N (2006). Disrupted fat absorption attenuates obesity induced by a high-fat diet in Clock mutant mice. FEBS Lettr, 580:127-30.
-
(2006)
FEBS Lettr
, vol.580
, pp. 127-130
-
-
Oishi, K.1
Atsumi, G.2
Sugiyama, S.3
Kodomari, I.4
Kasamatsu, M.5
Machida, K.6
Ishida, N.7
-
159
-
-
61449266421
-
PERIOD2 is a circadian negative regulator of PAI-1 gene expression in mice
-
Oishi K, Miyazaki K, Uchida D, Ohkura N, Wakabayashi, M, Doi R, Matsuda J, Ishida N (2009). PERIOD2 is a circadian negative regulator of PAI-1 gene expression in mice. J Mol Cellul Cardiol, 46:545-52.
-
(2009)
J Mol Cellul Cardiol
, vol.46
, pp. 545-552
-
-
Oishi, K.1
Miyazaki, K.2
Uchida, D.3
Ohkura, N.4
Wakabayashi, M.5
Doi, R.6
Matsuda, J.7
Ishida, N.8
-
160
-
-
69949091182
-
Is the oxidative stress theory of aging dead?
-
Perez VI, Bokov A, Van Remmen H, Mele J, Ran Q, Ikeno Y, Richardson A (2009). Is the oxidative stress theory of aging dead? Biochim Biophys Acta, 1790:1005-14.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1005-1014
-
-
Perez, V.I.1
Bokov, A.2
Van Remmen, H.3
Mele, J.4
Ran, Q.5
Ikeno, Y.6
Richardson, A.7
-
161
-
-
3242737464
-
Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila
-
Miwa S, Riyahi K, Partridge L, Brand MD (2004). Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila Ann NY Acad Sci, 1019:388-91.
-
(2004)
Ann NY Acad Sci
, vol.1019
, pp. 388-391
-
-
Miwa, S.1
Riyahi, K.2
Partridge, L.3
Brand, M.D4
-
162
-
-
50949112045
-
The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms
-
Buffenstein R, Edrey YH, Yang T, Mele J (2008). The oxidative stress theory of aging: embattled or invincible? Insights from non-traditional model organisms. AGE, 30:99-109.
-
(2008)
AGE
, vol.30
, pp. 99-109
-
-
Buffenstein, R.1
Edrey, Y.H.2
Yang, T.3
Mele, J.4
-
163
-
-
57749095081
-
Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans
-
Doonan R, McElwee JJ, Matthijssens F, Walker GA, Houthoofd K, Back P, Matscheski A, Vanfleteren JR, Gems D (2008). Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans. Genes Dev, 22:3236-3324.
-
(2008)
Genes Dev
, vol.22
, pp. 3236-3324
-
-
Doonan, R.1
McElwee, J.J.2
Matthijssens, F.3
Walker, G.A.4
Houthoofd, K.5
Back, P.6
Matscheski, A.7
Vanfleteren, J.R.8
Gems, D.9
-
164
-
-
76749106883
-
Oxidative stress and aging in the nematode Caenorhabditis elegans
-
In: Miwa S, Beckman KB, Muller FL, editors., From model systems to human diseases. Totowa NJ: Humana Press
-
Gems D, Doonan R (2008). Oxidative stress and aging in the nematode Caenorhabditis elegans. In: Miwa S, Beckman KB, Muller FL, editors. Oxidative stress in aging: From model systems to human diseases. Totowa NJ: Humana Press, 81-110.
-
(2008)
Oxidative stress in aging
, pp. 81-110
-
-
Gems, D.1
Doonan, R.2
-
165
-
-
50649101095
-
Puzzles, promises and a cure for ageing
-
Vijg J, Campisi J (2008). Puzzles, promises and a cure for ageing. Nature, 454:1065-71.
-
(2008)
Nature
, vol.454
, pp. 1065-1071
-
-
Vijg, J.1
Campisi, J.2
-
166
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A (2003). Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol Genomics, 16: 29-37.
-
(2003)
Physiol Genomics
, vol.16
, pp. 29-37
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
Pahlavani, M.4
Wolf, N.5
Thorpe, S.R.6
Alderson, N.L.7
Baynes, J.W.8
Epstein, C.J.9
Huang, T.T.10
Nelson, J.11
Strong, R.12
Richardson, A.13
-
167
-
-
70349693474
-
Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span
-
Salmon AB, Perez VI, Bokov A, Jernigan A, Kim G, Zhao H, Levine RL, Richardson A (2009). Lack of methionine sulfoxide reductase A in mice increases sensitivity to oxidative stress but does not diminish life span. FASEB J, 23:3601-8.
-
(2009)
FASEB J
, vol.23
, pp. 3601-3608
-
-
Salmon, A.B.1
Perez, V.I.2
Bokov, A.3
Jernigan, A.4
Kim, G.5
Zhao, H.6
Levine, R.L.7
Richardson, A.8
-
168
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly YM, Gidlof S, Oldfors A, Wibom R, Tornell J, Jacobs HT, Larsson NG (2004). Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature, 429:417-23.
-
(2004)
Nature
, vol.429
, pp. 417-423
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
169
-
-
34047116291
-
Mitochondrial point mutations do not limit the natural lifespan of mice
-
Vermulst M, Bielas JH, Kujoth GC, Ladiges WC, Rabinovitch PS, Prolla TA, Loeb LA (2007). Mitochondrial point mutations do not limit the natural lifespan of mice. Nature Genet, 39:540-3.
-
(2007)
Nature Genet
, vol.39
, pp. 540-543
-
-
Vermulst, M.1
Bielas, J.H.2
Kujoth, G.C.3
Ladiges, W.C.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
170
-
-
29144458899
-
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
-
Trifunovic A, Hansson A, Wredenberg A, Rovio AT, Dufour E, Khvorostov I, Spelbrink JN, Wibom R, Jacobs HT, Larsson NG (2005). Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc. Natl. Acad. Sci. USA, 102:17993-8.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 17993-17998
-
-
Trifunovic, A.1
Hansson, A.2
Wredenberg, A.3
Rovio, A.T.4
Dufour, E.5
Khvorostov, I.6
Spelbrink, J.N.7
Wibom, R.8
Jacobs, H.T.9
Larsson, N.G.10
-
171
-
-
41349087783
-
DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice.
-
Vermulst M, Wanagat J, Kujoth GC, Bielas JH, Rabinovitch PS, Prolla TA, Loeb LA (2008). DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice. Nature Genet 2008; 40:392-4.
-
(2008)
Nature Genet
, vol.2008
, Issue.40
, pp. 392-394
-
-
Vermulst, M.1
Wanagat, J.2
Kujoth, G.C.3
Bielas, J.H.4
Rabinovitch, P.S.5
Prolla, T.A.6
Loeb, L.A.7
-
172
-
-
38349108752
-
Mitochondrial dysfunction as a cause of ageing
-
Trifunovic A, Larsson NG (2008). Mitochondrial dysfunction as a cause of ageing. J Intern Med, 263:167-78.
-
(2008)
J Intern Med
, vol.263
, pp. 167-178
-
-
Trifunovic, A.1
Larsson, N.G.2
-
173
-
-
34547956260
-
Testing the rate-of-living/oxidative damage theory of aging in the nematode model Caenorhabditis elegans
-
Brys K, Vanfleteren JR, Braeckman BP (2007). Testing the rate-of-living/oxidative damage theory of aging in the nematode model Caenorhabditis elegans. Exp Gerontol, 42:845-851.
-
(2007)
Exp Gerontol
, vol.42
, pp. 845-851
-
-
Brys, K.1
Vanfleteren, J.R.2
Braeckman, B.P.3
-
174
-
-
44649200532
-
Intermediary metabolism
-
In: Kuwabara P editor. TheWormbook.
-
Braeckman BP, Houthoofd K, Vanfleteren JR (2009). Intermediary metabolism. In: Kuwabara P editor. TheWormbook.
-
(2009)
-
-
Braeckman, B.P.1
Houthoofd, K.2
Vanfleteren, J.R3
-
175
-
-
55849152355
-
Aging: ROS or TOR
-
Blagosklonny MV (2008). Aging: ROS or TOR. Cell Cycle, 7:3344-3354.
-
(2008)
Cell Cycle
, vol.7
, pp. 3344-3354
-
-
Blagosklonny, M.V.1
-
176
-
-
55749105400
-
Gene expression changes in the course of normal brain aging are sexually dimorphic
-
Berchtold NC, Cribbs DH, Coleman PD, Rogers J, Head E, Kim R, Beach T, Miller C, Troncoso J, Trojanowski JQ, Zielke HR, Cotman CW (2008). Gene expression changes in the course of normal brain aging are sexually dimorphic. Proc. Natl. Acad. Sci. USA, 105:15605-10.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 15605-15610
-
-
Berchtold, N.C.1
Cribbs, D.H.2
Coleman, P.D.3
Rogers, J.4
Head, E.5
Kim, R.6
Beach, T.7
Miller, C.8
Troncoso, J.9
Trojanowski, J.Q.10
Zielke, H.R.11
Cotman, C.W.12
-
177
-
-
57649245230
-
Phosphorylation of the translation initiation factor eIF2 increases BACE1 levels and promotes amyloidogenesis
-
O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Leslie BH, Bembinster LA, Lammich S, Lichtenthaler SF, Henert SS, De Strooper B, Haass C, Bennet DA, Vassar R (2008). Phosphorylation of the translation initiation factor eIF2 increases BACE1 levels and promotes amyloidogenesis. Neuron, 60:988-1009.
-
(2008)
Neuron
, vol.60
, pp. 988-1009
-
-
O'Connor, T.1
Sadleir, K.R.2
Maus, E.3
Velliquette, R.A.4
Zhao, J.5
Cole, S.L.6
Eimer, W.A.7
Leslie, B.H.8
Bembinster, L.A.9
Lammich, S.10
Lichtenthaler, S.F.11
Henert, S.S.12
De Strooper, B.13
Haass, C.14
Bennet, D.A.15
Vassar, R.16
-
179
-
-
0029125857
-
Aging, energy, and oxidative stress in neurodegenerative diseases
-
Beal MF (1995). Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol, 38:357-66.
-
(1995)
Ann Neurol
, vol.38
, pp. 357-366
-
-
Beal, M.F.1
-
180
-
-
4544235673
-
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
-
Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS (2004). Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol, 287:C817-C833.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
, pp. C817-C833
-
-
Brookes, P.S.1
Yoon, Y.2
Robotham, J.L.3
Anders, M.W.4
Sheu, S.S.5
-
181
-
-
39349111970
-
Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis
-
Ricci C, Pastukh V, Leonard J, Turrens J, Wilson G, Schaffer D, Schaffer SW (2008). Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis. Am J Physiol Cell Physiol, 294:C413-C422.
-
(2008)
Am J Physiol Cell Physiol
, vol.294
, pp. C413-C422
-
-
Ricci, C.1
Pastukh, V.2
Leonard, J.3
Turrens, J.4
Wilson, G.5
Schaffer, D.6
Schaffer, S.W.7
-
182
-
-
34548379027
-
Multidisciplinary aspects of regulatory systems relevant to multiple stressors: aging, xenobiotics and radiation.
-
In: Mothersill C, editor., New York: Springer
-
Rollo CD (2007). Multidisciplinary aspects of regulatory systems relevant to multiple stressors: aging, xenobiotics and radiation. In: Mothersill C, editor. Multiple stressors: A challenge for the future. New York: Springer, 185-224.
-
(2007)
Multiple stressors: A challenge for the future
, pp. 185-224
-
-
Rollo, C.D1
-
183
-
-
0003693103
-
-
London: University of London Press
-
Pearl R. The Rate of Living. London: University of London Press; 1928.
-
(1928)
The Rate of Living
-
-
Pearl, R.1
-
184
-
-
18944388449
-
Body size, metabolism and lifespan
-
Speakman JR (2005). Body size, metabolism and lifespan. J Exp Biol, 208:1717-30.
-
(2005)
J Exp Biol
, vol.208
, pp. 1717-1730
-
-
Speakman, J.R.1
-
185
-
-
3843070757
-
Starvation response in mouse liver shows strong correlation with life-span-prolonging processes
-
Bauer M, Hamm AC, Bonaus M, Jacob A, Jaekel J, Schorle H, Pankratz MJ, Katzenberger JD (2004). Starvation response in mouse liver shows strong correlation with life-span-prolonging processes. Physiol Genomics, 17:230-244.
-
(2004)
Physiol Genomics
, vol.17
, pp. 230-244
-
-
Bauer, M.1
Hamm, A.C.2
Bonaus, M.3
Jacob, A.4
Jaekel, J.5
Schorle, H.6
Pankratz, M.J.7
Katzenberger, J.D.8
-
187
-
-
0003681241
-
Size, Function, and Life History.
-
Cambridge: Harvard University Press
-
Calder WA. Size, Function, and Life History. Cambridge: Harvard University Press; 1984.
-
(1984)
-
-
Calder, W.A.1
-
188
-
-
78651491365
-
Metabolism and longevity: Is there a role for membrane fatty acids?
-
Hulbert AJ (2010). Metabolism and longevity: Is there a role for membrane fatty acids? Integr Comp Biol
-
(2010)
Integr Comp Biol
-
-
Hulbert, A.J1
-
189
-
-
79952129167
-
Functional linkages for the pace of life, life-history, and environment in birds.
-
Williams JB, Miller RA, Harper JM, Wiersma P (2010). Functional linkages for the pace of life, life-history, and environment in birds. Integr Comp Biol.
-
(2010)
Integr Comp Biol
-
-
Williams, J.B.1
Miller, R.A.2
Harper, J.M.3
Wiersma, P.4
-
190
-
-
77049308856
-
Aging: a theory based on free radical and radiation chemistry
-
Harman D (1956). Aging: a theory based on free radical and radiation chemistry. J Gerontol, 11:298-300.
-
(1956)
J Gerontol
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
191
-
-
0015319592
-
The biologic clock: the mitochondria?
-
Harman D (1972). The biologic clock: the mitochondria? J Am Geriatr Soc, 20:145-7.
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
192
-
-
0000098878
-
Antioxidants, aging and longevity.
-
In: Pryor WA, editor., New York: Academic Press
-
Cutler RG (1984). Antioxidants, aging and longevity. In: Pryor WA, editor. Free radicals in biology Vol VI. New York: Academic Press, 371-428.
-
(1984)
Free radicals in biology
, vol.6
, pp. 371-428
-
-
Cutler, R.G1
-
193
-
-
0006550943
-
Evolutionary biology of aging and longevity in mammalian species.
-
In: Johnson JE, editor., New York: Plenum Press
-
Cutler, RG (1984). Evolutionary biology of aging and longevity in mammalian species. In: Johnson JE, editor. Aging and cell function. New York: Plenum Press, 1-147.
-
(1984)
Aging and cell function
, pp. 1-147
-
-
Cutler, R.G.1
-
194
-
-
7044239977
-
Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer
-
Speakman JR, Talbot DA, Selman C, Snart S, McLaren JS, Redman P, Krol E, Jackson DM, Johnson MS, Brand MD (2004). Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell, 3:87-95.
-
(2004)
Aging Cell
, vol.3
, pp. 87-95
-
-
Speakman, J.R.1
Talbot, D.A.2
Selman, C.3
Snart, S.4
McLaren, J.S.5
Redman, P.6
Krol, E.7
Jackson, D.M.8
Johnson, M.S.9
Brand, M.D.10
-
195
-
-
76749103305
-
A dietary supplement ameliorates locomotor, neurotransmitter and mitochondrial aging
-
Aksenov V, Long J, Lokuge S, Foster JA, Liu J, Rollo, CD (2010). A dietary supplement ameliorates locomotor, neurotransmitter and mitochondrial aging. Exp Biol Med, 335:66-76.
-
(2010)
Exp Biol Med
, vol.335
, pp. 66-76
-
-
Aksenov, V.1
Long, J.2
Lokuge, S.3
Foster, J.A.4
Liu, J.5
Rollo, C.D.6
-
196
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN (1998). The free radical theory of aging matures. Physiol Rev, 78:547-81.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
197
-
-
0036596625
-
Endogenous oxidative stress: relationship to aging, longevity and caloric restriction
-
Barja G (2002). Endogenous oxidative stress: relationship to aging, longevity and caloric restriction. Ageing Res Rev, 1:397-411.
-
(2002)
Ageing Res Rev
, vol.1
, pp. 397-411
-
-
Barja, G.1
-
198
-
-
0036829433
-
Rate of generation of oxidative stress related damage to animal longevity
-
Barja G. (2002). Rate of generation of oxidative stress related damage to animal longevity. Free Radical Biol Med, 33: 1167-1172.
-
(2002)
Free Radical Biol Med
, vol.33
, pp. 1167-1172
-
-
Barja, G.1
-
199
-
-
4544322045
-
Free radicals and aging
-
Barja G (2004). Free radicals and aging. Trends Neurosci, 27:595-600.
-
(2004)
Trends Neurosci
, vol.27
, pp. 595-600
-
-
Barja, G.1
-
200
-
-
4043147798
-
Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins
-
Brand MD, Affourtit C, Esteves TC, Green K, Lambert AL, Miwa S, Pakay JL, Parker N (2004). Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins. Free Radical Biol Med, 37:755-767.
-
(2004)
Free Radical Biol Med
, vol.37
, pp. 755-767
-
-
Brand, M.D.1
Affourtit, C.2
Esteves, T.C.3
Green, K.4
Lambert, A.L.5
Miwa, S.6
Pakay, J.L.7
Parker, N.8
-
201
-
-
34249683717
-
An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts
-
de Magalhaes JP, Costa J, Church GM (2007). An analysis of the relationship between metabolism, developmental schedules, and longevity using phylogenetic independent contrasts. J Gerontol A Biol Sci Med Sci, 62:149-160.
-
(2007)
J Gerontol A Biol Sci Med Sci
, vol.62
, pp. 149-160
-
-
de Magalhaes, J.P.1
Costa, J.2
Church, G.M.3
-
202
-
-
50949111534
-
Energetics and longevity of birds
-
Furness LJ, Speakman JR (2008). Energetics and longevity of birds. AGE, 30:75-87.
-
(2008)
AGE
, vol.30
, pp. 75-87
-
-
Furness, L.J.1
Speakman, J.R.2
-
203
-
-
47949092183
-
An analysis of the factors that influence the level and scaling of mammalian BMR
-
McNab BK (2008). An analysis of the factors that influence the level and scaling of mammalian BMR. Comp Biochem Physiol A, 151:5-28.
-
(2008)
Comp Biochem Physiol A
, vol.151
, pp. 5-28
-
-
McNab, B.K.1
-
204
-
-
38949145803
-
A systematic look at an old problem
-
Kirkwood TBL (2008). A systematic look at an old problem. Nature, 451:644-7.
-
(2008)
Nature
, vol.451
, pp. 644-647
-
-
Kirkwood, T.B.L.1
-
205
-
-
78651294960
-
The heat dissipation limit theory and evolution of life histories in endotherms - time to dispose of the disposable soma theory?
-
Speakman JR, Krol E (2010). The heat dissipation limit theory and evolution of life histories in endotherms - time to dispose of the disposable soma theory? Integ Comp Biol.
-
(2010)
Integ Comp Biol.
-
-
Speakman, J.R.1
Krol, E.2
-
206
-
-
77957017481
-
Maximal heat dissipation capacity and hyperthermia risk: neglected key factors in the ecology of endotherms
-
Speakman JR, Krol E (2010). Maximal heat dissipation capacity and hyperthermia risk: neglected key factors in the ecology of endotherms J Anim Ecol, 79:726-46.
-
(2010)
J Anim Ecol
, vol.79
, pp. 726-746
-
-
Speakman, J.R.1
Krol, E.2
-
207
-
-
1842687156
-
Toward a metabolic theory of ecology
-
Brown JH, Gillooly JF, Allen AP, Savage VM, West GB (2004). Toward a metabolic theory of ecology. Ecology, 85:1771-89.
-
(2004)
Ecology
, vol.85
, pp. 1771-1789
-
-
Brown, J.H.1
Gillooly, J.F.2
Allen, A.P.3
Savage, V.M.4
West, G.B.5
-
208
-
-
1642368948
-
The predominance of quarter-power scaling in biology.
-
Savage VM, Gillooly JF, WoodruffWH, West GB, Allen AP, Enquist BJ, Brown JH (2004).The predominance of quarter-power scaling in biology. Funct Ecol, 18:257-282.
-
(2004)
Funct Ecol
, vol.18
, pp. 257-282
-
-
Savage, V.M.1
Gillooly, J.F.2
Woodruff, W.H.3
West, G.B.4
Allen, A.P.5
Enquist, B.J.6
Brown, J.H7
-
209
-
-
18944373435
-
Exercise-induced maximal metabolic rate scales with muscle aerobic capacity
-
Weibel ER, Hoppeler H (2005). Exercise-induced maximal metabolic rate scales with muscle aerobic capacity. J Exp Biol, 208:1635-44.
-
(2005)
J Exp Biol
, vol.208
, pp. 1635-1644
-
-
Weibel, E.R.1
Hoppeler, H.2
-
210
-
-
74549188409
-
A unifying explanation for diverse metabolic scaling in animals and plants
-
Glazier DS (2010). A unifying explanation for diverse metabolic scaling in animals and plants. Biol Rev, 85:111-38.
-
(2010)
Biol Rev
, vol.85
, pp. 111-138
-
-
Glazier, D.S.1
-
211
-
-
77950439987
-
Scaling of basal metabolic rate with body mass and temperature in mammals
-
Clarke A, Rothery P, Isaac NJB (2010). Scaling of basal metabolic rate with body mass and temperature in mammals. J Anim Ecol, 79:610-619.
-
(2010)
J Anim Ecol
, vol.79
, pp. 610-619
-
-
Clarke, A.1
Rothery, P.2
Isaac, N.J.B.3
-
213
-
-
0030766632
-
Lifetime reproduction of giant transgenic mice: the energy stress paradigm
-
Rollo CD, Rintoul J, Kajiura LJ (1997). Lifetime reproduction of giant transgenic mice: the energy stress paradigm. Can J Zool, 75:1336-45.
-
(1997)
Can J Zool
, vol.75
, pp. 1336-1345
-
-
Rollo, C.D.1
Rintoul, J.2
Kajiura, L.J.3
-
214
-
-
70349860194
-
Phylogenetically informed analysis of the allometry of mammalian basal metabolic rate supports neither geometric nor quarter-power scaling
-
White CR, Blackburn TM, Seymour RS (2009). Phylogenetically informed analysis of the allometry of mammalian basal metabolic rate supports neither geometric nor quarter-power scaling. Evolution, 63:2658-67.
-
(2009)
Evolution
, vol.63
, pp. 2658-2667
-
-
White, C.R.1
Blackburn, T.M.2
Seymour, R.S.3
-
215
-
-
34247119565
-
Allometric exponents do not support a universal metabolic allometry
-
White CR, Cassey P, Blackburn TM (2007). Allometric exponents do not support a universal metabolic allometry. Ecology, 88:315-23.
-
(2007)
Ecology
, vol.88
, pp. 315-323
-
-
White, C.R.1
Cassey, P.2
Blackburn, T.M.3
-
216
-
-
18944396166
-
Field metabolic rate and body size
-
Nagy KA (2005). Field metabolic rate and body size. J Exp Biol, 208:1621-25.
-
(2005)
J Exp Biol
, vol.208
, pp. 1621-1625
-
-
Nagy, K.A.1
-
218
-
-
2342550096
-
Allometric scaling of maximal metabolic rate in mammals: muscle aerobic capacity as determinant factor
-
Weibel ER, Bacigalupe LD, Schmitt B, Hoppeler H (2004). Allometric scaling of maximal metabolic rate in mammals: muscle aerobic capacity as determinant factor. Respir Physiol Neurobiol, 140:115-32.
-
(2004)
Respir Physiol Neurobiol
, vol.140
, pp. 115-132
-
-
Weibel, E.R.1
Bacigalupe, L.D.2
Schmitt, B.3
Hoppeler, H.4
-
219
-
-
0026046722
-
On the relation between basal and field metabolic rates in birds and mammals
-
Koteja P (1991). On the relation between basal and field metabolic rates in birds and mammals. Funct Ecol, 5:56-64.
-
(1991)
Funct Ecol
, vol.5
, pp. 56-64
-
-
Koteja, P.1
-
220
-
-
0029139093
-
Scaling of field metabolic rate to basal metabolic rate ratio in homeotherms
-
Degen AA, Kam M (1995). Scaling of field metabolic rate to basal metabolic rate ratio in homeotherms. Ecoscience, 2:48-54.
-
(1995)
Ecoscience
, vol.2
, pp. 48-54
-
-
Degen, A.A.1
Kam, M.2
-
221
-
-
67649347537
-
Growth and aging: a common molecular mechanism
-
Blagosklonny MV, Hall MN (2009). Growth and aging: a common molecular mechanism. Aging, 1: 357-62.
-
(2009)
Aging
, vol.1
, pp. 357-362
-
-
Blagosklonny, M.V.1
Hall, M.N.2
-
222
-
-
34249104544
-
Oxidative stress and aberrant signaling in aging and cognitive decline
-
Droge W, Schipper HM (2007). Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell, 6:361-70.
-
(2007)
Aging Cell
, vol.6
, pp. 361-370
-
-
Droge, W.1
Schipper, H.M.2
-
223
-
-
33751170896
-
Long-lived αMUPA transgenic mice exhibit pronounced circadian rhythms
-
Froy O, Chapnik N, Miskin R (2006). Long-lived αMUPA transgenic mice exhibit pronounced circadian rhythms. Am J Physiol Endocrinol Metab, 291:E1017-E1024.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
, pp. E1017-E1024
-
-
Froy, O.1
Chapnik, N.2
Miskin, R.3
-
224
-
-
0016356803
-
Mammalian sleep, longevity, and energy metabolism
-
Zeplin H, Rechtschaffen A (1974). Mammalian sleep, longevity, and energy metabolism. Brain Behav Evol, 10:425-70.
-
(1974)
Brain Behav Evol
, vol.10
, pp. 425-470
-
-
Zeplin, H.1
Rechtschaffen, A.2
|