Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

Genes and Development

Volumn 20, Issue 3, 2006, Pages 267-275

  Levine, Arnold J ^a,b   Feng, Zhaohui ^b   Mak, Tak W ^c   You, Han ^c   Jin, Shengkan ^b,d  

^a INSTITUTE FOR ADVANCED STUDY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

p53 AKT; p53 TOR; Pathway, interactions

Indexed keywords

GROWTH FACTOR; PROTEIN KINASE B; PROTEIN P53; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

CARCINOGENESIS; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; DIABETES MELLITUS; FLY; GENE FUNCTION; GENE IDENTIFICATION; GENITAL SYSTEM; HUMAN; LONGEVITY; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SENSE ORGAN; SIGNAL TRANSDUCTION; WORM;

ANIMALS; ENZYME ACTIVATION; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; ONCOGENE PROTEIN V-AKT; PROTEIN KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

MAMMALIA;

EID: 32044435126     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1363206     Document Type: Review

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