메뉴 건너뛰기




Volumn 105, Issue 40, 2008, Pages 15605-15610

Gene expression changes in the course of normal brain aging are sexually dimorphic

Author keywords

Entorhinal cortex; Hippocampus; Microarray; Sex differences; Superior frontal gyrus

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN REGION; CATABOLISM; CONTROLLED STUDY; DOWN REGULATION; ENTORHINAL CORTEX; FEMALE; FOREBRAIN; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MALE; NERVE DEGENERATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SEX DIFFERENCE; SUBICULUM;

EID: 55749105400     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806883105     Document Type: Article
Times cited : (476)

References (31)
  • 1
    • 0037242125 scopus 로고    scopus 로고
    • Aging and the human neocortex
    • Pakkenberg B, et al. (2003) Aging and the human neocortex. Exp Gerontol 38:95-99.
    • (2003) Exp Gerontol , vol.38 , pp. 95-99
    • Pakkenberg, B.1
  • 2
    • 0023156372 scopus 로고
    • Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia
    • Flood DG, Buell SJ, Horwitz GJ, Coleman PD (1987) Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia. Brain Res 402:205-216.
    • (1987) Brain Res , vol.402 , pp. 205-216
    • Flood, D.G.1    Buell, S.J.2    Horwitz, G.J.3    Coleman, P.D.4
  • 3
    • 0023214421 scopus 로고
    • Dendritic extent in human CA2-3 hippocampal pyramidal neurons in normal aging and senile dementia
    • Flood DG, Guarnaccia M, Coleman PD (1987) Dendritic extent in human CA2-3 hippocampal pyramidal neurons in normal aging and senile dementia. Brain Res 409:88-96.
    • (1987) Brain Res , vol.409 , pp. 88-96
    • Flood, D.G.1    Guarnaccia, M.2    Coleman, P.D.3
  • 4
    • 34247213423 scopus 로고    scopus 로고
    • Alterations of synaptic turnover rate in aging may trigger senile plaque formation and neurodegeneration
    • Bertoni-Freddari C, et al. (2007) Alterations of synaptic turnover rate in aging may trigger senile plaque formation and neurodegeneration. Ann NY Acad Sci 1096:128-137.
    • (2007) Ann NY Acad Sci , vol.1096 , pp. 128-137
    • Bertoni-Freddari, C.1
  • 5
    • 3042631024 scopus 로고    scopus 로고
    • Gene regulation and DNA damage in the aging human brain
    • Lu T, et al. (2004) Gene regulation and DNA damage in the aging human brain. Nature 429:883-891.
    • (2004) Nature , vol.429 , pp. 883-891
    • Lu, T.1
  • 6
    • 14644394263 scopus 로고    scopus 로고
    • Molecular aging in human prefrontal cortex is selective and continuous throughout adult life
    • Erraji-Benchekroun L, et al. (2005) Molecular aging in human prefrontal cortex is selective and continuous throughout adult life. Biol Psychiatry 57:549-558.
    • (2005) Biol Psychiatry , vol.57 , pp. 549-558
    • Erraji-Benchekroun, L.1
  • 7
    • 0031935568 scopus 로고    scopus 로고
    • Sex differences in brain aging: A quantitative magnetic resonance imaging study
    • Coffey CE, et al. (1998) Sex differences in brain aging: A quantitative magnetic resonance imaging study. Arch Neurol 55:169-179.
    • (1998) Arch Neurol , vol.55 , pp. 169-179
    • Coffey, C.E.1
  • 8
    • 0033562871 scopus 로고    scopus 로고
    • Sex differences in brain gray and white matter in healthy young adults: Correlations with cognitive performance
    • Gur RC, et al. (1999) Sex differences in brain gray and white matter in healthy young adults: Correlations with cognitive performance. J Neurosci 19:4065-4072.
    • (1999) J Neurosci , vol.19 , pp. 4065-4072
    • Gur, R.C.1
  • 9
    • 0036143543 scopus 로고    scopus 로고
    • Brain region and sex differences in age association with brain volume: A quantitative MRI study of healthy young adults
    • Gur RC, Gunning-Dixon FM, Turetsky BI, Bilker WB, Gur RE (2002) Brain region and sex differences in age association with brain volume: A quantitative MRI study of healthy young adults. Am J Geriatr Psychiatry 10:72-80.
    • (2002) Am J Geriatr Psychiatry , vol.10 , pp. 72-80
    • Gur, R.C.1    Gunning-Dixon, F.M.2    Turetsky, B.I.3    Bilker, W.B.4    Gur, R.E.5
  • 10
    • 8944220721 scopus 로고    scopus 로고
    • Sex differences in human brain morphometry and metabolism: An in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging
    • Murphy DG, et al. (1996) Sex differences in human brain morphometry and metabolism: An in vivo quantitative magnetic resonance imaging and positron emission tomography study on the effect of aging. Arch Gen Psychiatry 53:585-594.
    • (1996) Arch Gen Psychiatry , vol.53 , pp. 585-594
    • Murphy, D.G.1
  • 11
    • 33746681910 scopus 로고    scopus 로고
    • Tissue-specific expression and regulation of sexually dimorphic genes in mice
    • Yang X, et al. (2006) Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res 16:995-1004.
    • (2006) Genome Res , vol.16 , pp. 995-1004
    • Yang, X.1
  • 12
    • 33644511402 scopus 로고    scopus 로고
    • Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: Statistical reliability and functional correlation
    • Blalock EM, et al. (2005) Harnessing the power of gene microarrays for the study of brain aging and Alzheimer's disease: Statistical reliability and functional correlation. Aging Res Rev 4:481-512.
    • (2005) Aging Res Rev , vol.4 , pp. 481-512
    • Blalock, E.M.1
  • 13
    • 0346801873 scopus 로고    scopus 로고
    • The Gene Ontology (GO) database and informatics resource
    • Harris MA, et al. (2004) The Gene Ontology (GO) database and informatics resource. Nucleic Acids Res 32:D258-D261.
    • (2004) Nucleic Acids Res , vol.32
    • Harris, M.A.1
  • 15
    • 0032916242 scopus 로고    scopus 로고
    • Aging and the occurrence of dementia: Findings from a population-based cohort with a large sample of nonagenarians
    • von Strauss E, Viitanen M, De Ronchi D, Winblad B, Fratiglioni L (1999) Aging and the occurrence of dementia: Findings from a population-based cohort with a large sample of nonagenarians. Arch Neurol 56:587-592.
    • (1999) Arch Neurol , vol.56 , pp. 587-592
    • von Strauss, E.1    Viitanen, M.2    De Ronchi, D.3    Winblad, B.4    Fratiglioni, L.5
  • 17
    • 0038206578 scopus 로고    scopus 로고
    • Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
    • Blalock EM, et al. (2003) Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 23:3807-3819.
    • (2003) J Neurosci , vol.23 , pp. 3807-3819
    • Blalock, E.M.1
  • 18
    • 0035852759 scopus 로고    scopus 로고
    • The effects of aging on gene expression in the hypothalamus and cortex of mice
    • Jiang CH, Tsien JZ, Schultz PG, Hu Y (2001) The effects of aging on gene expression in the hypothalamus and cortex of mice. Proc Natl Acad Sci USA 98:1930-1934.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1930-1934
    • Jiang, C.H.1    Tsien, J.Z.2    Schultz, P.G.3    Hu, Y.4
  • 19
    • 0000847978 scopus 로고    scopus 로고
    • Gene-expression profile of the ageing brain in mice
    • Lee CK, Weindruch R, Prolla TA (2000) Gene-expression profile of the ageing brain in mice. Nat Genet 25:294-297.
    • (2000) Nat Genet , vol.25 , pp. 294-297
    • Lee, C.K.1    Weindruch, R.2    Prolla, T.A.3
  • 20
    • 0029067185 scopus 로고
    • Regional cerebral function determined by FDG-PET in healthy volunteers: Normal patterns and changes with age
    • Loessner A, et al. (1995) Regional cerebral function determined by FDG-PET in healthy volunteers: Normal patterns and changes with age. J Nucl Med 36:1141-1149.
    • (1995) J Nucl Med , vol.36 , pp. 1141-1149
    • Loessner, A.1
  • 22
    • 0037099764 scopus 로고    scopus 로고
    • Gender differences in cerebral glucose metabolism: A PET study
    • Kawachi T, et al. (2002) Gender differences in cerebral glucose metabolism: A PET study. J Neurol Sci 199:79-83.
    • (2002) J Neurol Sci , vol.199 , pp. 79-83
    • Kawachi, T.1
  • 24
    • 33750076373 scopus 로고    scopus 로고
    • The effect of gender on planning: An fMRI study using the Tower of London task
    • Boghi A, et al. (2006) The effect of gender on planning: An fMRI study using the Tower of London task. NeuroImage 33:999-1010.
    • (2006) NeuroImage , vol.33 , pp. 999-1010
    • Boghi, A.1
  • 25
    • 33748289476 scopus 로고    scopus 로고
    • Gender differences in the neural correlates of response inhibition during a stop signal task
    • Li CS, Huang C, Constable RT, Sinha R (2006) Gender differences in the neural correlates of response inhibition during a stop signal task. NeuroImage 32:1918-1929.
    • (2006) NeuroImage , vol.32 , pp. 1918-1929
    • Li, C.S.1    Huang, C.2    Constable, R.T.3    Sinha, R.4
  • 26
    • 2542550527 scopus 로고    scopus 로고
    • Sex-related hemispheric lateralization of amygdala function in emotionally influenced memory: An FMRI investigation
    • Cahill L, Uncapher M, Kilpatrick L, Alkire MT, Turner J (2004) Sex-related hemispheric lateralization of amygdala function in emotionally influenced memory: An FMRI investigation. Learn Mem 11:261-266.
    • (2004) Learn Mem , vol.11 , pp. 261-266
    • Cahill, L.1    Uncapher, M.2    Kilpatrick, L.3    Alkire, M.T.4    Turner, J.5
  • 27
    • 16344386418 scopus 로고    scopus 로고
    • Gender differences in the functional neuroanatomy of emotional episodic autobiographical memory
    • Piefke M, Weiss PH, Markowitsch HJ, Fink GR (2005) Gender differences in the functional neuroanatomy of emotional episodic autobiographical memory. Hum Brain Mapp 24:313-324.
    • (2005) Hum Brain Mapp , vol.24 , pp. 313-324
    • Piefke, M.1    Weiss, P.H.2    Markowitsch, H.J.3    Fink, G.R.4
  • 28
    • 84975806501 scopus 로고    scopus 로고
    • Inflammatory networks in ageing, Age-related diseases and longevity
    • Vasto S, et al. (2007) Inflammatory networks in ageing, Age-related diseases and longevity. Mech Aging Dev 128:83-91.
    • (2007) Mech Aging Dev , vol.128 , pp. 83-91
    • Vasto, S.1
  • 30
    • 34248576240 scopus 로고    scopus 로고
    • New perspectives on Mars and Venus: Unraveling the role of androgens in gender differences in cardiovascular biology and disease
    • Ng MK (2007) New perspectives on Mars and Venus: Unraveling the role of androgens in gender differences in cardiovascular biology and disease. Heart Lung Circ 16:185-192.
    • (2007) Heart Lung Circ , vol.16 , pp. 185-192
    • Ng, M.K.1
  • 31
    • 0030779518 scopus 로고    scopus 로고
    • Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain
    • Shen Y, Li R, McGeer EG, McGeer PL (1997) Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain. Brain Res 769:391-395.
    • (1997) Brain Res , vol.769 , pp. 391-395
    • Shen, Y.1    Li, R.2    McGeer, E.G.3    McGeer, P.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.