Mitochondrial DNA damage triggers mitochondrial-superoxide generation and apoptosis

American Journal of Physiology - Cell Physiology

Volumn 294, Issue 2, 2008, Pages

  Ricci, Craig ^a   Pastukh, Viktor ^a   Leonard, Josh ^c   Turrens, Julio ^b   Wilson, Glenn ^b   Schaffer, David ^c   Schaffer, Stephen W ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTH ALABAMA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Angiotensin II; Mitochondrial permeability transition pore; NADPH oxidase

Indexed keywords

8 HYDROXYGUANINE; ANGIOTENSIN II; CYTOCHROME C; DNA GLYCOSYLTRANSFERASE; LENTIVIRUS VECTOR; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL RESPIRATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NEWBORN; NONHUMAN; OXIDATION; PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL RESPIRATION; CYTOCHROMES C; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; DNA, MITOCHONDRIAL; ENDOPEPTIDASES; MEMBRANE POTENTIAL, MITOCHONDRIAL; NADPH OXIDASE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDES;

EID: 39349111970     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00362.2007     Document Type: Article

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