메뉴 건너뛰기




Volumn 69, Issue 6, 2012, Pages 915-930

Regulation of cholesterol homeostasis

Author keywords

Cholesterol homeostasis; HDL; MicroRNAs; SREBP

Indexed keywords

ABC TRANSPORTER A1; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INDUCIBLE DEGRADER OF THE LDL RECEPTOR; MICRORNA; MICRORNA 33A; MICRORNA 33B; PCSK9 PROTEIN; REGULATOR PROTEIN; SQUALENE MONOOXYGENASE; STEROL CARRIER PROTEIN 2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 84857647590     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-011-0857-5     Document Type: Review
Times cited : (159)

References (179)
  • 2
    • 4644372454 scopus 로고    scopus 로고
    • Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation
    • DOI 10.1016/j.yexcr.2004.06.029, PII S0014482704003854
    • Fernandez C, Lobo Md Mdel V, Gomez-Coronado D, Lasuncion MA (2004) Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. Exp Cell Res 300 (1): 109-120 (Pubitemid 39286221)
    • (2004) Experimental Cell Research , vol.300 , Issue.1 , pp. 109-120
    • Fernandez, C.1    Lobo, M.D.V.T.2    Gomez-Coronado, D.3    Lasuncion, M.A.4
  • 3
    • 27244433832 scopus 로고    scopus 로고
    • Effects of distal cholesterol biosynthesis inhibitors on cell proliferation and cell cycle progression
    • Fernandez C, Martin M, Gomez-Coronado D, Lasuncion MA (2005) Effects of distal cholesterol biosynthesis inhibitors on cell proliferation and cell cycle progression. J Lipid Res 46 (5): 920-929
    • (2005) J Lipid Res , vol.46 , Issue.5 , pp. 920-929
    • Fernandez, C.1    Martin, M.2    Gomez-Coronado, D.3    Lasuncion, M.A.4
  • 4
    • 33749464296 scopus 로고    scopus 로고
    • Mechanisms for cellular cholesterol transport: Defects and human disease
    • DOI 10.1152/physrev.00022.2005
    • Ikonen E (2006) Mechanisms for cellular cholesterol transport: defects and human disease. Physiol Rev 86 (4): 1237-1261 (Pubitemid 44521652)
    • (2006) Physiological Reviews , vol.86 , Issue.4 , pp. 1237-1261
    • Ikonen, E.1
  • 5
    • 28444479505 scopus 로고    scopus 로고
    • Role of cholesterol and lipid organization in disease
    • DOI 10.1038/nature04399
    • Maxfield FR, Tabas I (2005) Role of cholesterol and lipid organization in disease. Nature 438 (7068): 612-621 (Pubitemid 41740565)
    • (2005) Nature , vol.438 , Issue.7068 , pp. 612-621
    • Maxfield, F.R.1    Tabas, I.2
  • 6
    • 0026639957 scopus 로고
    • Sterol molecule: Structure, biosyn thesis, and function
    • Bloch K (1992) Sterol molecule: structure, biosynthesis, and function. Steroids 57 (8): 378-383
    • (1992) Steroids , vol.57 , Issue.8 , pp. 378-383
    • Bloch, K.1
  • 7
    • 59349094067 scopus 로고
    • The utilization of acetate for the synthesis of fatty acids, cholesterol, and protoporphyrin
    • Ponticorvo L, Rittenberg D, Bloch K (1949) The utilization of acetate for the synthesis of fatty acids, cholesterol, and protoporphyrin. J Biol Chem 179 (2): 839-842
    • (1949) J Biol Chem , vol.179 , Issue.2 , pp. 839-842
    • Ponticorvo, L.1    Rittenberg, D.2    Bloch, K.3
  • 8
    • 0017239547 scopus 로고
    • Receptor-mediated control of cholesterol metabolism
    • Brown MS, Goldstein JL (1976) Receptor-mediated control of cholesterol metabolism. Science 191 (4223): 150-154
    • (1976) Science , vol.191 , Issue.4223 , pp. 150-154
    • Brown, M.S.1    Goldstein, J.L.2
  • 9
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown MS, Goldstein JL (1986) A receptor-mediated pathway for cholesterol homeostasis. Science 232 (4746): 34-47 (Pubitemid 16037973)
    • (1986) Science , vol.232 , Issue.4746 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 10
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • DOI 10.1016/S0092-8674(00)80213-5
    • Brown MS, Goldstein JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membranebound transcription factor. Cell 89 (3): 331-340 (Pubitemid 27220877)
    • (1997) Cell , vol.89 , Issue.3 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 11
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein JL, Brown MS (1990) Regulation of the mevalonate pathway. Nature 343 (6257): 425-430
    • (1990) Nature , vol.343 , Issue.6257 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 13
    • 32944473282 scopus 로고    scopus 로고
    • Nuclear receptors in lipid metabolism: Targeting the heart of dyslipidemia
    • DOI 10.1146/annurev.med.57.121304.131428
    • Beaven SW, Tontonoz P (2006) Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia. Annu Rev Med 57: 313-329 (Pubitemid 43261994)
    • (2006) Annual Review of Medicine , vol.57 , pp. 313-329
    • Beaven, S.W.1    Tontonoz, P.2
  • 15
    • 0037503924 scopus 로고    scopus 로고
    • Liver X receptor signaling pathways in cardiovascular disease
    • DOI 10.1210/me.2003-0061
    • Tontonoz P, Mangelsdorf DJ (2003) Liver X receptor signaling pathways in cardiovascular disease. Mol Endocrinol 17 (6): 985-993 (Pubitemid 36683707)
    • (2003) Molecular Endocrinology , vol.17 , Issue.6 , pp. 985-993
    • Tontonoz, P.1    Mangelsdorf, D.J.2
  • 18
    • 77955456415 scopus 로고    scopus 로고
    • MiR-33 links SREBP-2 induction to repression of sterol transporters
    • Marquart TJ, Allen RM, Ory DS, Baldan A (2010) miR-33 links SREBP-2 induction to repression of sterol transporters. Proc Natl Acad Sci USA 107 (27): 12228-12232
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.27 , pp. 12228-12232
    • Marquart, T.J.1    Allen, R.M.2    Ory, D.S.3    Baldan, A.4
  • 23
    • 67649349865 scopus 로고    scopus 로고
    • MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages
    • Chen T, Huang Z, Wang L, Wang Y, Wu F, Meng S, Wang C (2009) MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages. Cardiovasc Res 83 (1): 131-139
    • (2009) Cardiovasc Res , vol.83 , Issue.1 , pp. 131-139
    • Chen, T.1    Huang, Z.2    Wang, L.3    Wang, Y.4    Wu, F.5    Meng, S.6    Wang, C.7
  • 27
    • 77952707662 scopus 로고    scopus 로고
    • MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism
    • Iliopoulos D, Drosatos K, Hiyama Y, Goldberg IJ, Zannis VI (2010) MicroRNA-370 controls the expression of microRNA- 122 and Cpt1alpha and affects lipid metabolism. J Lipid Res 51 (6): 1513-1523
    • (2010) J Lipid Res , vol.51 , Issue.6 , pp. 1513-1523
    • Iliopoulos, D.1    Drosatos, K.2    Hiyama, Y.3    Goldberg, I.J.4    Zannis, V.I.5
  • 28
    • 63049108381 scopus 로고    scopus 로고
    • A role of miR-27 in the regulation of adipogenesis
    • Lin Q, Gao Z, Alarcon RM, Ye J, Yun Z (2009) A role of miR- 27 in the regulation of adipogenesis. FEBS J 276 (8): 2348-2358
    • (2009) FEBS J , vol.276 , Issue.8 , pp. 2348-2358
    • Lin, Q.1    Gao, Z.2    Alarcon, R.M.3    Ye, J.4    Yun, Z.5
  • 30
    • 0027501003 scopus 로고
    • Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
    • Dietschy JM, Turley SD, Spady DK (1993) Role of liver in the maintenance of cholesterol and low-density lipoprotein homeostasis in different animal species, including humans. J Lipid Res 34 (10): 1637-1659 (Pubitemid 23298709)
    • (1993) Journal of Lipid Research , vol.34 , Issue.10 , pp. 1637-1659
    • Dietschy, J.M.1    Turley, S.D.2    Spady, D.K.3
  • 32
    • 38049175023 scopus 로고    scopus 로고
    • Statins: A new insight into their mechanisms of action and consequent pleiotropic effects
    • Jasinska M, Owczarek J, Orszulak-Michalak D (2007) Statins: a new insight into their mechanisms of action and consequent pleiotropic effects. Pharmacol Rep 59 (5): 483-499
    • (2007) Pharmacol Rep , vol.59 , Issue.5 , pp. 483-499
    • Jasinska, M.1    Owczarek, J.2    Orszulak-Michalak, D.3
  • 33
    • 0001415416 scopus 로고
    • Preputial gland tumor sterols. 3. A metabolic pathway from lanosterol to cholesterol
    • Kandutsch AA, Russell AE (1960) Preputial gland tumor sterols. 3. A metabolic pathway from lanosterol to cholesterol. J Biol Chem 235: 2256-2261
    • (1960) J Biol Chem , vol.235 , pp. 2256-2261
    • Kandutsch, A.A.1    Russell, A.E.2
  • 34
    • 17144403817 scopus 로고    scopus 로고
    • Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration
    • DOI 10.1021/bi048296z
    • Baumann NA, Sullivan DP, Ohvo-Rekila H, Simonot C, Pottekat A, Klaassen Z, Beh CT, Menon AK (2005) Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration. Biochemistry 44 (15): 5816-5826 (Pubitemid 40525118)
    • (2005) Biochemistry , vol.44 , Issue.15 , pp. 5816-5826
    • Baumann, N.A.1    Sullivan, D.P.2    Ohvo-Rekila, H.3    Simonot, C.4    Pottekat, A.5    Klaassen, Z.6    Beh, C.T.7    Menon, A.K.8
  • 35
    • 0030943621 scopus 로고    scopus 로고
    • Acyl-coenzyme A: Cholesterol acyltransferase
    • DOI 10.1146/annurev.biochem.66.1.613
    • Chang TY, Chang CC, Cheng D (1997) Acyl-coenzyme A: cholesterol acyltransferase. Annu Rev Biochem 66: 613-638 (Pubitemid 27274669)
    • (1997) Annual Review of Biochemistry , vol.66 , pp. 613-638
    • Chang, T.Y.1    Chang, C.C.Y.2    Cheng, D.3
  • 36
    • 0019135838 scopus 로고
    • Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth
    • Brown MS, Goldstein JL (1980) Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. J Lipid Res 21 (5): 505-517 (Pubitemid 11194847)
    • (1980) Journal of Lipid Research , vol.21 , Issue.5 , pp. 505-517
    • Brown, M.S.1    Goldstein, J.L.2
  • 37
    • 0033055564 scopus 로고    scopus 로고
    • Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae
    • DOI 10.1080/096876899294607
    • Hooper NM (1999) Detergent-insoluble glycosphingolipid/cholesterol- rich membrane domains, lipid rafts and caveolae (review). Mol Membr Biol 16 (2): 145-156 (Pubitemid 29308814)
    • (1999) Molecular Membrane Biology , vol.16 , Issue.2 , pp. 145-156
    • Hooper, N.M.1
  • 38
    • 0034793082 scopus 로고    scopus 로고
    • Genetic disorders of cholesterol biosynthesis in mice and humans
    • DOI 10.1006/mgme.2001.3226
    • Nwokoro NA, Wassif CA, Porter FD (2001) Genetic disorders of cholesterol biosynthesis in mice and humans. Mol Genet Metab 74 (1-2): 105-119 (Pubitemid 32955152)
    • (2001) Molecular Genetics and Metabolism , vol.74 , Issue.1-2 , pp. 105-119
    • Nwokoro, N.A.1    Wassif, C.A.2    Porter, F.D.3
  • 39
    • 0000139419 scopus 로고
    • A newly recognized syndrome of multiple congenital anomalies
    • Smith DW, Lemli L, Opitz JM (1964) A newly recognized syndrome of multiple congenital anomalies. J Pediatr 64: 210-217
    • (1964) J Pediatr , vol.64 , pp. 210-217
    • Smith, D.W.1    Lemli, L.2    Opitz, J.M.3
  • 41
    • 0035083555 scopus 로고    scopus 로고
    • Cholesterol metabolism in the brain
    • DOI 10.1097/00041433-200104000-00003
    • Dietschy JM, Turley SD (2001) Cholesterol metabolism in the brain. Curr Opin Lipidol 12 (2): 105-112 (Pubitemid 32242918)
    • (2001) Current Opinion in Lipidology , vol.12 , Issue.2 , pp. 105-112
    • Dietschy, J.M.1    Turley, S.D.2
  • 42
    • 0028801536 scopus 로고
    • Cholesterol for synthesis of myelin is made locally, not imported into brain
    • Jurevics H, Morell P (1995) Cholesterol for synthesis of myelin is made locally, not imported into brain. J Neurochem 64 (2): 895-901
    • (1995) J Neurochem , vol.64 , Issue.2 , pp. 895-901
    • Jurevics, H.1    Morell, P.2
  • 44
    • 22144439346 scopus 로고    scopus 로고
    • Lovastatin-induced PC-12 cell differentiation is associated with RhoA/RhoA kinase pathway inactivation
    • DOI 10.1016/j.mcn.2005.04.012, PII S1044743105000989
    • Fernandez-Hernando C, Suarez Y, Lasuncion MA (2005) Lovastatin- induced PC-12 cell differentiation is associated with RhoA/RhoA kinase pathway inactivation. Mol Cell Neurosci 29 (4): 591-602 (Pubitemid 40984700)
    • (2005) Molecular and Cellular Neuroscience , vol.29 , Issue.4 , pp. 591-602
    • Fernandez-Hernando, C.1    Suarez, Y.2    Lasuncion, M.A.3
  • 45
    • 1842790914 scopus 로고    scopus 로고
    • Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures
    • DOI 10.1074/jbc.M313828200
    • Hayashi H, Campenot RB, Vance DE, Vance JE (2004) Glial lipoproteins stimulate axon growth of central nervous system neurons in compartmented cultures. J Biol Chem 279 (14): 14009-14015 (Pubitemid 38468935)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.14 , pp. 14009-14015
    • Hayashi, H.1    Campenot, R.B.2    Vance, D.E.3    Vance, J.E.4
  • 46
    • 0028822219 scopus 로고
    • Low-density lipoprotein receptorrelated protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line
    • Holtzman DM, Pitas RE, Kilbridge J, Nathan B, Mahley RW, Bu G, Schwartz AL (1995) Low-density lipoprotein receptorrelated protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line. Proc Natl Acad Sci USA 92 (21): 9480-9484
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.21 , pp. 9480-9484
    • Holtzman, D.M.1    Pitas, R.E.2    Kilbridge, J.3    Nathan, B.4    Mahley, R.W.5    Bu, G.6    Schwartz, A.L.7
  • 47
    • 75849142894 scopus 로고    scopus 로고
    • Shoulson i Altered cholesterol and fatty acid metabolism in Huntington disease
    • Block RC, Dorsey ER, Beck CA, Brenna JT, Shoulson I Altered cholesterol and fatty acid metabolism in Huntington disease. J Clin Lipidol 4 (1): 17-23
    • J Clin Lipidol , vol.4 , Issue.1 , pp. 17-23
    • Block, R.C.1    Dorsey, E.R.2    Beck, C.A.3    Brenna, J.T.4
  • 50
    • 0020472786 scopus 로고
    • The LDL receptor defect in familial hypercholesterolemia. Implications for pathogenesis and therapy
    • Goldstein JL, Brown MS (1982) The LDL receptor defect in familial hypercholesterolemia. Implications for pathogenesis and therapy. Med Clin North Am 66 (2): 335-362 (Pubitemid 12115370)
    • (1982) Medical Clinics of North America , vol.66 , Issue.2 , pp. 335-362
    • Goldstein, J.L.1    Brown, M.S.2
  • 51
    • 0021010872 scopus 로고
    • Absorption and metabolism of dietary cholesterol
    • Grundy SM (1983) Absorption and metabolism of dietary cholesterol. Annu Rev Nutr 3: 71-96
    • (1983) Annu Rev Nutr , vol.3 , pp. 71-96
    • Grundy, S.M.1
  • 54
    • 1542719049 scopus 로고    scopus 로고
    • The niemann-pick disease genes: Regulators of cellular cholesterol homeostasis
    • DOI 10.1016/j.tcm.2003.12.003, PII S1050173803001956
    • Ory DS (2004) The Niemann-Pick disease genes; regulators of cellular cholesterol homeostasis. Trends Cardiovasc Med 14 (2): 66-72 (Pubitemid 38340849)
    • (2004) Trends in Cardiovascular Medicine , vol.14 , Issue.2 , pp. 66-72
    • Ory, D.S.1
  • 55
    • 78649916808 scopus 로고    scopus 로고
    • Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes
    • Wang ML, Motamed M, Infante RE, Abi-Mosleh L, Kwon HJ, Brown MS, Goldstein JL (2010) Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes. Cell Metab 12 (2): 166-173
    • (2010) Cell Metab , vol.12 , Issue.2 , pp. 166-173
    • Wang, M.L.1    Motamed, M.2    Infante, R.E.3    Abi-Mosleh, L.4    Kwon, H.J.5    Brown, M.S.6    Goldstein, J.L.7
  • 57
    • 33745846377 scopus 로고    scopus 로고
    • Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1-deficient cells
    • DOI 10.1074/jbc.M601679200
    • Ganley IG, Pfeffer SR (2006) Cholesterol accumulation sequesters Rab9 and disrupts late endosome function in NPC1- deficient cells. J Biol Chem 281 (26): 17890-17899 (Pubitemid 44035588)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.26 , pp. 17890-17899
    • Ganley, I.G.1    Pfeffer, S.R.2
  • 58
    • 0036791574 scopus 로고    scopus 로고
    • Intracellular cholesterol transport
    • Maxfield FR, Wustner D (2002) Intracellular cholesterol transport. J Clin Invest 110 (7): 891-898
    • (2002) J Clin Invest , vol.110 , Issue.7 , pp. 891-898
    • Maxfield, F.R.1    Wustner, D.2
  • 59
    • 33745457968 scopus 로고    scopus 로고
    • Sterol and lipid trafficking in mammalian cells
    • DOI 10.1042/BST0340335
    • Maxfield FR, Mondal M (2006) Sterol and lipid trafficking in mammalian cells. Biochem Soc Trans 34 (Pt 3): 335-339 (Pubitemid 43953980)
    • (2006) Biochemical Society Transactions , vol.34 , Issue.3 , pp. 335-339
    • Maxfield, F.R.1    Mondal, M.2
  • 61
    • 0037591389 scopus 로고    scopus 로고
    • StAR-related lipid transfer (START) proteins: Mediators of intracellular lipid metabolism
    • DOI 10.1074/jbc.R300003200
    • Soccio RE, Breslow JL (2003) StAR-related lipid transfer (START) proteins: mediators of intracellular lipid metabolism. J Biol Chem 278 (25): 22183-22186 (Pubitemid 36830262)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.25 , pp. 22183-22186
    • Soccio, R.E.1    Breslow, J.L.2
  • 64
    • 34848880480 scopus 로고    scopus 로고
    • Non-vesicular sterol transport in cells
    • DOI 10.1016/j.plipres.2007.06.002, PII S0163782707000264
    • Prinz WA (2007) Non-vesicular sterol transport in cells. Prog Lipid Res 46 (6): 297-314 (Pubitemid 47496070)
    • (2007) Progress in Lipid Research , vol.46 , Issue.6 , pp. 297-314
    • Prinz, W.A.1
  • 65
    • 15944365201 scopus 로고    scopus 로고
    • Caveolin, cholesterol, and lipid bodies
    • DOI 10.1016/j.semcdb.2005.01.007, Cellular Cholesterol Metabolism and Trafficking and Apoptosis in Development
    • Martin S, Parton RG (2005) Caveolin, cholesterol, and lipid bodies. Semin Cell Dev Biol 16 (2): 163-174 (Pubitemid 40432118)
    • (2005) Seminars in Cell and Developmental Biology , vol.16 , Issue.2 , pp. 163-174
    • Martin, S.1    Parton, R.G.2
  • 66
    • 33847181297 scopus 로고    scopus 로고
    • The multiple faces of caveolae
    • Parton RG, Simons K (2007) The multiple faces of caveolae. Nat Rev Mol Cell Biol 8 (3): 185-194
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.3 , pp. 185-194
    • Parton, R.G.1    Simons, K.2
  • 67
    • 0034682847 scopus 로고    scopus 로고
    • Palmitoylation of caveolin-1 is required for cholesterol binding, chaperone complex formation, and rapid transport of cholesterol to caveolae
    • Uittenbogaard A, Smart EJ (2000) Palmitoylation of caveolin-1 is required for cholesterol binding, chaperone complex formation, and rapid transport of cholesterol to caveolae. J Biol Chem 275 (33): 25595-25599
    • (2000) J Biol Chem , vol.275 , Issue.33 , pp. 25595-25599
    • Uittenbogaard, A.1    Smart, E.J.2
  • 68
    • 0032513038 scopus 로고    scopus 로고
    • Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking
    • DOI 10.1074/jbc.273.11.6525
    • Uittenbogaard A, Ying Y, Smart EJ (1998) Characterization of a cytosolic heat-shock protein-caveolin chaperone complex. Involvement in cholesterol trafficking. J Biol Chem 273 (11): 6525-6532 (Pubitemid 28144750)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.11 , pp. 6525-6532
    • Uittenbogaard, A.1    Ying, Y.-S.2    Smart, E.J.3
  • 70
    • 0019809230 scopus 로고
    • Assay of oxysterol-binding protein in a mouse fibroblast, cell-free system. Dissociation constant and other properties of the system
    • Kandutsch AA, Shown EP (1981) Assay of oxysterol-binding protein in a mouse fibroblast, cell-free system. Dissociation constant and other properties of the system. J Biol Chem 256 (24): 13068-13073 (Pubitemid 12131971)
    • (1981) Journal of Biological Chemistry , vol.256 , Issue.24 , pp. 13068-13073
    • Kandutsch, A.A.1    Shown, E.P.2
  • 71
    • 0036472330 scopus 로고    scopus 로고
    • Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments
    • DOI 10.1042/0264-6021:3610461
    • Wang C, JeBailey L, Ridgway ND (2002) Oxysterol-bindingprotein (OSBP) -related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments. Biochem J 361 (Pt 3): 461-472 (Pubitemid 34177815)
    • (2002) Biochemical Journal , vol.361 , Issue.3 , pp. 461-472
    • Wang, C.1    JeBailey, L.2    Ridgway, N.D.3
  • 72
    • 65249161758 scopus 로고    scopus 로고
    • Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function
    • Ngo M, Ridgway ND (2009) Oxysterol binding protein-related Protein 9 (ORP9) is a cholesterol transfer protein that regulates Golgi structure and function. Mol Biol Cell 20 (5): 1388-1399
    • (2009) Mol Biol Cell , vol.20 , Issue.5 , pp. 1388-1399
    • Ngo, M.1    Ridgway, N.D.2
  • 73
    • 0037342401 scopus 로고    scopus 로고
    • The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct
    • DOI 10.1091/mbc.E02-08-0459
    • Johansson M, Bocher V, Lehto M, Chinetti G, Kuismanen E, Ehnholm C, Staels B, Olkkonen VM (2003) The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct. Mol Biol Cell 14 (3): 903-915 (Pubitemid 36337441)
    • (2003) Molecular Biology of the Cell , vol.14 , Issue.3 , pp. 903-915
    • Johansson, M.1    Bocher, V.2    Lehto, M.3    Chinetti, G.4    Kuismanen, E.5    Ehnholm, C.6    Staels, B.7    Olkkonen, V.M.8
  • 75
    • 0032901292 scopus 로고    scopus 로고
    • START: A lipid-binding domain in StAR, HD-ZIP and signalling proteins
    • DOI 10.1016/S0968-0004(99)01362-6, PII S0968000499013626
    • Ponting CP, Aravind L (1999) START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins. Trends Biochem Sci 24 (4): 130-132 (Pubitemid 29222709)
    • (1999) Trends in Biochemical Sciences , vol.24 , Issue.4 , pp. 130-132
    • Ponting, C.P.1    Aravind, L.2
  • 76
    • 0035047848 scopus 로고    scopus 로고
    • StAR protein and the regulation of steroid hormone biosynthesis
    • DOI 10.1146/annurev.physiol.63.1.193
    • Stocco DM (2001) StAR protein and the regulation of steroid hormone biosynthesis. Annu Rev Physiol 63: 193-213 (Pubitemid 32304316)
    • (2001) Annual Review of Physiology , vol.63 , pp. 193-213
    • Stocco, D.M.1
  • 77
    • 0347611095 scopus 로고    scopus 로고
    • Molecular machinery for non-vesicular trafficking of ceramide
    • DOI 10.1038/nature02188
    • Hanada K, Kumagai K, Yasuda S, Miura Y, Kawano M, Fukasawa M, Nishijima M (2003) Molecular machinery for nonvesicular trafficking of ceramide. Nature 426 (6968): 803-809 (Pubitemid 38056858)
    • (2003) Nature , vol.426 , Issue.6968 , pp. 803-809
    • Hanada, K.1    Kumagai, K.2    Yasuda, S.3    Miura, Y.4    Kawano, M.5    Fukasawa, M.6    Nishijima, M.7
  • 78
    • 77956863466 scopus 로고    scopus 로고
    • STARTing to understand MLN64 function in cholesterol transport
    • Rigotti A, Cohen DE, Zanlungo S (2010) STARTing to understand MLN64 function in cholesterol transport. J Lipid Res 51 (8): 2015-2017
    • (2010) J Lipid Res , vol.51 , Issue.8 , pp. 2015-2017
    • Rigotti, A.1    Cohen, D.E.2    Zanlungo, S.3
  • 79
    • 77951087930 scopus 로고    scopus 로고
    • MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein
    • Charman M, Kennedy BE, Osborne N, Karten B (2010) MLN64 mediates egress of cholesterol from endosomes to mitochondria in the absence of functional Niemann-Pick Type C1 protein. J Lipid Res 51 (5): 1023-1034
    • (2010) J Lipid Res , vol.51 , Issue.5 , pp. 1023-1034
    • Charman, M.1    Kennedy, B.E.2    Osborne, N.3    Karten, B.4
  • 80
    • 0015547302 scopus 로고
    • The metabolic role of lecithin: Cholesterol acyltransferase: Perspectives form pathology
    • Glomset JA, Norum KR (1973) The metabolic role of lecithin: cholesterol acyltransferase: perspectives form pathology. Adv Lipid Res 11: 1-65
    • (1973) Adv Lipid Res , vol.11 , pp. 1-65
    • Glomset, J.A.1    Norum, K.R.2
  • 81
    • 33745132444 scopus 로고    scopus 로고
    • Macrophage reverse cholesterol transport: Key to the regression of atherosclerosis?
    • DOI 10.1161/CIRCULATIONAHA.104.475715, PII 0000301720060530000014
    • Cuchel M, Rader DJ (2006) Macrophage reverse cholesterol transport: key to the regression of atherosclerosis? Circulation 113 (21): 2548-2555 (Pubitemid 43948034)
    • (2006) Circulation , vol.113 , Issue.21 , pp. 2548-2555
    • Cuchel, M.1    Rader, D.J.2
  • 82
    • 0030480126 scopus 로고    scopus 로고
    • Apolipoprotein-mediated removal of cellular cholesterol and phospholipids
    • Oram JF, Yokoyama S (1996) Apolipoprotein-mediated removal of cellular cholesterol and phospholipids. J Lipid Res 37 (12): 2473-2491 (Pubitemid 27051496)
    • (1996) Journal of Lipid Research , vol.37 , Issue.12 , pp. 2473-2491
    • Oram, J.F.1    Yokoyama, S.2
  • 83
  • 84
    • 0034672673 scopus 로고    scopus 로고
    • Release of cellular cholesterol: Molecular mechanism for cholesterol homeostasis in cells and in the body
    • Yokoyama S (2000) Release of cellular cholesterol: molecular mechanism for cholesterol homeostasis in cells and in the body. Biochim Biophys Acta 1529 (1-3): 231-244
    • (2000) Biochim Biophys Acta , vol.1529 , Issue.1-3 , pp. 231-244
    • Yokoyama, S.1
  • 85
    • 0034672281 scopus 로고    scopus 로고
    • Lecithin cholesterol acyltransferase
    • Jonas A (2000) Lecithin cholesterol acyltransferase. Biochim Biophys Acta 1529 (1-3): 245-256
    • (2000) Biochim Biophys Acta , vol.1529 , Issue.1-3 , pp. 245-256
    • Jonas, A.1
  • 87
    • 67651085117 scopus 로고    scopus 로고
    • Lecithin: Cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo
    • Tanigawa H, Billheimer JT, Tohyama J, Fuki IV, Ng DS, Rothblat GH, Rader DJ (2009) Lecithin: cholesterol acyltransferase expression has minimal effects on macrophage reverse cholesterol transport in vivo. Circulation 120 (2): 160-169
    • (2009) Circulation , vol.120 , Issue.2 , pp. 160-169
    • Tanigawa, H.1    Billheimer, J.T.2    Tohyama, J.3    Fuki, I.V.4    Ng, D.S.5    Rothblat, G.H.6    Rader, D.J.7
  • 89
    • 14944381287 scopus 로고    scopus 로고
    • HDL as a target in the treatment of atherosclerotic cardiovascular disease
    • DOI 10.1038/nrd1658
    • Linsel-Nitschke P, Tall AR (2005) HDL as a target in the treatment of atherosclerotic cardiovascular disease. Nat Rev Drug Discov 4 (3): 193-205 (Pubitemid 40372554)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.3 , pp. 193-205
    • Linsel-Nitschke, P.1    Tall, A.R.2
  • 90
    • 17744390348 scopus 로고    scopus 로고
    • Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters
    • DOI 10.1126/science.290.5497.1771
    • Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH (2000) Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290 (5497): 1771-1775 (Pubitemid 32004809)
    • (2000) Science , vol.290 , Issue.5497 , pp. 1771-1775
    • Berge, K.E.1    Tian, H.2    Graf, G.A.3    Yu, L.4    Grishin, N.V.5    Schultz, J.6    Kwiterovich, P.7    Shan, B.8    Barnes, R.9    Hobbs, H.H.10
  • 91
    • 0016366624 scopus 로고
    • Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters
    • Bhattacharyya AK, Connor WE (1974) Beta-sitosterolemia and xanthomatosis. A newly described lipid storage disease in two sisters. J Clin Invest 53 (4): 1033-1043
    • (1974) J Clin Invest , vol.53 , Issue.4 , pp. 1033-1043
    • Bhattacharyya, A.K.1    Connor, W.E.2
  • 92
    • 0018841909 scopus 로고
    • Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: A case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis
    • Miettinen TA (1980) Phytosterolaemia, xanthomatosis and premature atherosclerotic arterial disease: a case with high plant sterol absorption, impaired sterol elimination and low cholesterol synthesis. Eur J Clin Invest 10 (1): 27-35 (Pubitemid 10133847)
    • (1980) European Journal of Clinical Investigation , vol.10 , Issue.1 , pp. 27-35
    • Miettinen, T.A.1
  • 93
    • 33745791394 scopus 로고    scopus 로고
    • ABCA1 and biogenesis of HDL
    • Yokoyama S (2006) ABCA1 and biogenesis of HDL. J Atheroscler Thromb 13 (1): 1-15
    • (2006) J Atheroscler Thromb , vol.13 , Issue.1 , pp. 1-15
    • Yokoyama, S.1
  • 94
    • 42649134146 scopus 로고    scopus 로고
    • HDL, ABC transporters, and cholesterol efflux: Implications for the treatment of atherosclerosis
    • DOI 10.1016/j.cmet.2008.03.001, PII S1550413108000727
    • Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N (2008) HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. Cell Metab 7 (5): 365-375 (Pubitemid 351598023)
    • (2008) Cell Metabolism , vol.7 , Issue.5 , pp. 365-375
    • Tall, A.R.1    Yvan-Charvet, L.2    Terasaka, N.3    Pagler, T.4    Wang, N.5
  • 101
    • 64349093470 scopus 로고    scopus 로고
    • ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity
    • Nandi S, Ma L, Denis M, Karwatsky J, Li Z, Jiang XC, Zha X (2009) ABCA1-mediated cholesterol efflux generates microparticles in addition to HDL through processes governed by membrane rigidity. J Lipid Res 50 (3): 456-466
    • (2009) J Lipid Res , vol.50 , Issue.3 , pp. 456-466
    • Nandi, S.1    Ma, L.2    Denis, M.3    Karwatsky, J.4    Li, Z.5    Jiang, X.C.6    Zha, X.7
  • 102
    • 0142042380 scopus 로고    scopus 로고
    • ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions
    • DOI 10.1194/jlr.M300078-JLR200
    • Vaughan AM, Oram JF (2003) ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions. J Lipid Res 44 (7): 1373-1380 (Pubitemid 37279619)
    • (2003) Journal of Lipid Research , vol.44 , Issue.7 , pp. 1373-1380
    • Vaughan, A.M.1    Oram, J.F.2
  • 103
    • 34548364160 scopus 로고    scopus 로고
    • Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles
    • DOI 10.1074/jbc.M704590200
    • Vedhachalam C, Duong PT, Nickel M, Nguyen D, Dhanasekaran P, Saito H, Rothblat GH, Lund-Katz S, Phillips MC (2007) Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of highdensity lipoprotein particles. J Biol Chem 282 (34): 25123-25130 (Pubitemid 47347535)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.34 , pp. 25123-25130
    • Vedhachalam, C.1    Duong, P.T.2    Nickel, M.3    Nguyen, D.4    Dhanasekaran, P.5    Saito, H.6    Rothblat, G.H.7    Lund-Katz, S.8    Phillips, M.C.9
  • 105
    • 78650623431 scopus 로고    scopus 로고
    • Reverse cholesterol transport: From classical view to new insights
    • van der Velde AE (2010) Reverse cholesterol transport: from classical view to new insights. World J Gastroenterol 16 (47): 5908-5915
    • (2010) World J Gastroenterol , vol.16 , Issue.47 , pp. 5908-5915
    • Van Der Velde, A.E.1
  • 107
    • 33845580066 scopus 로고    scopus 로고
    • ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL
    • DOI 10.1194/jlr.M600218-JLR200
    • Vaughan AM, Oram JF (2006) ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL. J Lipid Res 47 (11): 2433-2443 (Pubitemid 44936105)
    • (2006) Journal of Lipid Research , vol.47 , Issue.11 , pp. 2433-2443
    • Vaughan, A.M.1    Oram, J.F.2
  • 111
    • 0036251153 scopus 로고    scopus 로고
    • SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
    • DOI 10.1172/JCI200215593
    • Horton JD, Goldstein JL, Brown MS (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J Clin Invest 109 (9): 1125-1131 (Pubitemid 34496588)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.9 , pp. 1125-1131
    • Horton, J.D.1    Goldstein, J.L.2    Brown, M.S.3
  • 112
    • 0032892175 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins: Activators of cholesterol and fatty acid biosynthesis
    • DOI 10.1097/00041433-199904000-00008
    • Horton JD, Shimomura I (1999) Sterol regulatory elementbinding proteins: activators of cholesterol and fatty acid biosynthesis. Curr Opin Lipidol 10 (2): 143-150 (Pubitemid 29187097)
    • (1999) Current Opinion in Lipidology , vol.10 , Issue.2 , pp. 143-150
    • Horton, J.D.1    Shimomura, L.2
  • 113
    • 0027648820 scopus 로고
    • ADD1: A novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation
    • Tontonoz P, Kim JB, Graves RA, Spiegelman BM (1993) ADD1: a novel helix-loop-helix transcription factor associated with adipocyte determination and differentiation. Mol Cell Biol 13 (8): 4753-4759
    • (1993) Mol Cell Biol , vol.13 , Issue.8 , pp. 4753-4759
    • Tontonoz, P.1    Kim, J.B.2    Graves, R.A.3    Spiegelman, B.M.4
  • 114
    • 0030911517 scopus 로고    scopus 로고
    • Cleavage site for sterol-regulated protease localized to a Leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2
    • DOI 10.1074/jbc.272.19.12778
    • Duncan EA, Brown MS, Goldstein JL, Sakai J (1997) Cleavage site for sterol-regulated protease localized to a leu-Ser bond in the lumenal loop of sterol regulatory element-binding protein-2. J Biol Chem 272 (19): 12778-12785 (Pubitemid 27203378)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.19 , pp. 12778-12785
    • Duncan, E.A.1    Brown, M.S.2    Goldstein, J.L.3    Sakai, J.4
  • 116
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • DOI 10.1016/S0092-8674(02)00872-3
    • Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, Goldstein JL, Brown MS (2002) Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110 (4): 489-500 (Pubitemid 35232292)
    • (2002) Cell , vol.110 , Issue.4 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6    Goldstein, J.L.7    Brown, M.S.8
  • 119
    • 0034693259 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): Key regulators of nutritional homeostasis and insulin action
    • Osborne TF (2000) Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action. J Biol Chem 275 (42): 32379-32382
    • (2000) J Biol Chem , vol.275 , Issue.42 , pp. 32379-32382
    • Osborne, T.F.1
  • 120
    • 30344473341 scopus 로고    scopus 로고
    • Protein sensors for membrane sterols
    • Goldstein JL, DeBose-Boyd RA, Brown MS (2006) Protein sensors for membrane sterols. Cell 124 (1): 35-46
    • (2006) Cell , vol.124 , Issue.1 , pp. 35-46
    • Goldstein, J.L.1    Debose-Boyd, R.A.2    Brown, M.S.3
  • 121
    • 33645731353 scopus 로고    scopus 로고
    • SREBPs: Sterol-regulated transcription factors
    • Espenshade PJ (2006) SREBPs: sterol-regulated transcription factors. J Cell Sci 119 (Pt 6): 973-976
    • (2006) J Cell Sci , vol.119 , Issue.PART 6 , pp. 973-976
    • Espenshade, P.J.1
  • 123
    • 0037082099 scopus 로고    scopus 로고
    • Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesis
    • DOI 10.1006/abbi.2001.2615
    • Goldstein JL, Rawson RB, Brown MS (2002) Mutant mammalian cells as tools to delineate the sterol regulatory elementbinding protein pathway for feedback regulation of lipid synthesis. Arch Biochem Biophys 397 (2): 139-148 (Pubitemid 34852273)
    • (2002) Archives of Biochemistry and Biophysics , vol.397 , Issue.2 , pp. 139-148
    • Goldstein, J.L.1    Rawson, R.B.2    Brown, M.S.3
  • 124
    • 10044271037 scopus 로고    scopus 로고
    • SREBP transcription factors: Master regulators of lipid homeostasis
    • DOI 10.1016/j.biochi.2004.09.018, PII S0300908404001658, Recent Advances in Lipid Metabolism and Related Disorders
    • Eberle D, Hegarty B, Bossard P, Ferre P, Foufelle F (2004) SREBP transcription factors: master regulators of lipid homeostasis. Biochimie 86 (11): 839-848 (Pubitemid 39602764)
    • (2004) Biochimie , vol.86 , Issue.11 , pp. 839-848
    • Eberle, D.1    Hegarty, B.2    Bossard, P.3    Ferre, P.4    Foufelle, F.5
  • 127
    • 0035965231 scopus 로고    scopus 로고
    • Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway
    • Hirano Y, Yoshida M, Shimizu M, Sato R (2001) Direct demonstration of rapid degradation of nuclear sterol regulatory element-binding proteins by the ubiquitin-proteasome pathway. J Biol Chem 276 (39): 36431-36437
    • (2001) J Biol Chem , vol.276 , Issue.39 , pp. 36431-36437
    • Hirano, Y.1    Yoshida, M.2    Shimizu, M.3    Sato, R.4
  • 128
    • 0037930875 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway
    • DOI 10.1074/jbc.M212448200
    • Hirano Y, Murata S, Tanaka K, Shimizu M, Sato R (2003) Sterol regulatory element-binding proteins are negatively regulated through SUMO-1 modification independent of the ubiquitin/26 S proteasome pathway. J Biol Chem 278 (19): 16809-16819 (Pubitemid 36799550)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.19 , pp. 16809-16819
    • Hirano, Y.1    Murata, S.2    Tanaka, K.3    Shimizu, M.4    Sato, R.5
  • 131
    • 0034518420 scopus 로고    scopus 로고
    • The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
    • DOI 10.1146/annurev.cellbio.16.1.459
    • Repa JJ, Mangelsdorf DJ (2000) The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol 16: 459-481 (Pubitemid 32037514)
    • (2000) Annual Review of Cell and Developmental Biology , vol.16 , pp. 459-481
    • Repa, J.J.1    Mangelsdorf, D.J.2
  • 132
    • 0035205221 scopus 로고    scopus 로고
    • Pivotal role of ABCA1 in reverse cholesterol transport influencing HLD levels and susceptibility to atherosclerosis
    • Attie AD, Kastelein JP, Hayden MR (2001) Pivotal role of ABCA1 in reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis. J Lipid Res 42 (11): 1717-1726 (Pubitemid 33116703)
    • (2001) Journal of Lipid Research , vol.42 , Issue.11 , pp. 1717-1726
    • Attie, A.D.1    Kastelein, J.P.2    Hayden, M.R.3
  • 137
    • 18544378347 scopus 로고    scopus 로고
    • Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol
    • DOI 10.1016/j.cmet.2005.01.001, PII S1550413105000288
    • Song BL, Javitt NB, DeBose-Boyd RA (2005) Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol. Cell Metab 1 (3): 179-189 (Pubitemid 43960599)
    • (2005) Cell Metabolism , vol.1 , Issue.3 , pp. 179-189
    • Song, B.-L.1    Javitt, N.B.2    DeBose-Boyd, R.A.3
  • 138
    • 3142654791 scopus 로고    scopus 로고
    • Ubiquitination of 3-hydroxy-3-methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase
    • Song BL, DeBose-Boyd RA (2004) Ubiquitination of 3-hydroxy-3- methylglutaryl-CoA reductase in permeabilized cells mediated by cytosolic E1 and a putative membrane-bound ubiquitin ligase. J Biol Chem 279 (27): 28798-28806
    • (2004) J Biol Chem , vol.279 , Issue.27 , pp. 28798-28806
    • Song, B.L.1    Debose-Boyd, R.A.2
  • 139
    • 24944591120 scopus 로고    scopus 로고
    • Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase
    • DOI 10.1016/j.molcel.2005.08.009, PII S1097276505015273
    • Song BL, Sever N, DeBose-Boyd RA (2005) Gp78, a membrane- anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase. Mol Cell 19 (6): 829-840 (Pubitemid 41316676)
    • (2005) Molecular Cell , vol.19 , Issue.6 , pp. 829-840
    • Song, B.-L.1    Sever, N.2    DeBose-Boyd, R.A.3
  • 140
    • 0346101770 scopus 로고    scopus 로고
    • Insig-dependent Ubiquitination and Degradation of Mammalian 3-Hydroxy-3-methylglutaryl-CoA Reductase Stimulated by Sterols and Geranylgeraniol
    • DOI 10.1074/jbc.M310053200
    • Sever N, Song BL, Yabe D, Goldstein JL, Brown MS, DeBose- Boyd RA (2003) Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3- methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol. J Biol Chem 278 (52): 52479-52490 (Pubitemid 38035841)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.52 , pp. 52479-52490
    • Sever, N.1    Song, B.-L.2    Yabe, D.3    Goldstein, J.L.4    Brown, M.S.5    DeBose-Boydb, R.A.6
  • 141
    • 79952174597 scopus 로고    scopus 로고
    • Cholesteroldependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase
    • Gill S, Stevenson J, Kristiana I, Brown AJ (2011) Cholesteroldependent degradation of squalene monooxygenase, a control point in cholesterol synthesis beyond HMG-CoA reductase. Cell Metab 13 (3): 260-273
    • (2011) Cell Metab , vol.13 , Issue.3 , pp. 260-273
    • Gill, S.1    Stevenson, J.2    Kristiana, I.3    Brown, A.J.4
  • 142
    • 0015864346 scopus 로고
    • Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol
    • Beg ZH, Allmann DW, Gibson DM (1973) Modulation of 3-hydroxy-3- methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol. Biochem Biophys Res Commun 54 (4): 1362-1369
    • (1973) Biochem Biophys Res Commun , vol.54 , Issue.4 , pp. 1362-1369
    • Zh, B.1    Allmann, D.W.2    Gibson, D.M.3
  • 143
    • 0025310576 scopus 로고
    • Regulation of HMG-CoA reductase: Identification of the site phosphorylated by the AMPactivated protein kinase in vitro and in intact rat liver
    • Clarke PR, Hardie DG (1990) Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMPactivated protein kinase in vitro and in intact rat liver. EMBO J 9 (8): 2439-2446
    • (1990) EMBO J , vol.9 , Issue.8 , pp. 2439-2446
    • Clarke, P.R.1    Hardie, D.G.2
  • 144
    • 0036864358 scopus 로고    scopus 로고
    • Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase
    • DOI 10.1042/BST0301064
    • Hardie DG, Pan DA (2002) Regulation of fatty acid synthesis and oxidation by the AMP-activated protein kinase. Biochem Soc Trans 30 (Pt 6): 1064-1070 (Pubitemid 36002407)
    • (2002) Biochemical Society Transactions , vol.30 , Issue.6 , pp. 1064-1070
    • Hardie, D.G.1    Pan, D.A.2
  • 145
    • 0027428833 scopus 로고
    • Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion
    • DOI 10.1073/pnas.90.20.9261
    • Sato R, Goldstein JL, Brown MS (1993) Replacement of serine- 871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion. Proc Natl Acad Sci USA 90 (20): 9261-9265 (Pubitemid 23315763)
    • (1993) Proceedings of the National Academy of Sciences of the United States of America , vol.90 , Issue.20 , pp. 9261-9265
    • Sato, R.1    Goldstein, J.L.2    Brown, M.S.3
  • 146
    • 0028231978 scopus 로고
    • Modulation of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase activity by phosphorylation Role of serine 871
    • Omkumar RV, Darnay BG, Rodwell VW (1994) Modulation of Syrian hamster 3-hydroxy-3-methylglutaryl-CoA reductase activity by phosphorylation. Role of serine 871. J Biol Chem 269 (9): 6810-6814
    • (1994) J Biol Chem , vol.269 , Issue.9 , pp. 6810-6814
    • Omkumar, R.V.1    Darnay, B.G.2    Rodwell, V.W.3
  • 151
    • 67650092919 scopus 로고    scopus 로고
    • LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
    • Zelcer N, Hong C, Boyadjian R, Tontonoz P (2009) LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor. Science 325 (5936): 100-104
    • (2009) Science , vol.325 , Issue.5936 , pp. 100-104
    • Zelcer, N.1    Hong, C.2    Boyadjian, R.3    Tontonoz, P.4
  • 153
    • 0038343499 scopus 로고    scopus 로고
    • MicroRNA pathways in flies and worms: Growth, death, fat, stress, and timing
    • DOI 10.1016/S0092-8674(03)00428-8
    • Ambros V (2003) MicroRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 113 (6): 673-676 (Pubitemid 36724931)
    • (2003) Cell , vol.113 , Issue.6 , pp. 673-676
    • Ambros, V.1
  • 154
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • DOI 10.1038/nature02871
    • Ambros V (2004) The functions of animal microRNAs. Nature 431 (7006): 350-355 (Pubitemid 39265675)
    • (2004) Nature , vol.431 , Issue.7006 , pp. 350-355
    • Ambros, V.1
  • 155
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP (2009) MicroRNAs: target recognition and regulatory functions. Cell 136 (2): 215-233
    • (2009) Cell , vol.136 , Issue.2 , pp. 215-233
    • Bartel, D.P.1
  • 156
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9 (2): 102-114
    • (2008) Nat Rev Genet , vol.9 , Issue.2 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 158
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific MicroRNAs from mouse
    • DOI 10.1016/S0960-9822(02)00809-6, PII S0960982202008096
    • Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T (2002) Identification of tissue-specific microRNAs from mouse. Curr Biol 12 (9): 735-739 (Pubitemid 34455427)
    • (2002) Current Biology , vol.12 , Issue.9 , pp. 735-739
    • Lagos-Quintana, M.1    Rauhut, R.2    Yalcin, A.3    Meyer, J.4    Lendeckel, W.5    Tuschl, T.6
  • 165
    • 79551474502 scopus 로고    scopus 로고
    • Dysregulation of angiogenesis- related microRNAs in endothelial progenitor cells from patients with coronary artery disease
    • Zhang Q, Kandic I, Kutryk MJ (2010) Dysregulation of angiogenesis- related microRNAs in endothelial progenitor cells from patients with coronary artery disease. Biochem Biophys Res Commun 405 (1): 42-46
    • (2010) Biochem Biophys Res Commun , vol.405 , Issue.1 , pp. 42-46
    • Zhang, Q.1    Kandic, I.2    Kutryk, M.J.3
  • 166
    • 70349213385 scopus 로고    scopus 로고
    • Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster
    • Boettger T, Beetz N, Kostin S, Schneider J, Kruger M, Hein L, Braun T (2009) Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest 119 (9): 2634-2647
    • (2009) J Clin Invest , vol.119 , Issue.9 , pp. 2634-2647
    • Boettger, T.1    Beetz, N.2    Kostin, S.3    Schneider, J.4    Kruger, M.5    Hein, L.6    Braun, T.7
  • 175
    • 79953301730 scopus 로고    scopus 로고
    • MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
    • Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT (2011) MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol 13 (4): 423-433
    • (2011) Nat Cell Biol , vol.13 , Issue.4 , pp. 423-433
    • Vickers, K.C.1    Palmisano, B.T.2    Shoucri, B.M.3    Shamburek, R.D.4    Remaley, A.T.5
  • 176
    • 28344438648 scopus 로고    scopus 로고
    • A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPα regulates human granulopoiesis
    • DOI 10.1016/j.cell.2005.09.023, PII S0092867405009773
    • Fazi F, Rosa A, Fatica A, Gelmetti V, De Marchis ML, Nervi C, Bozzoni I (2005) A minicircuitry comprised of microRNA-223 and transcription factors NFI-A and C/EBPalpha regulates human granulopoiesis. Cell 123 (5): 819-831 (Pubitemid 41721029)
    • (2005) Cell , vol.123 , Issue.5 , pp. 819-831
    • Fazi, F.1    Rosa, A.2    Fatica, A.3    Gelmetti, V.4    De Marchis, M.L.5    Nervi, C.6    Bozzoni, I.7
  • 178
    • 34447262870 scopus 로고    scopus 로고
    • MicroRNA-223 is a key factor in osteoclast differentiation
    • DOI 10.1002/jcb.21335
    • Sugatani T, Hruska KA (2007) MicroRNA-223 is a key factor in osteoclast differentiation. J Cell Biochem 101 (4): 996-999 (Pubitemid 47040879)
    • (2007) Journal of Cellular Biochemistry , vol.101 , Issue.4 , pp. 996-999
    • Sugatani, T.1    Hruska, K.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.