MiR-145 and miR-143 regulate smooth muscle cell fate and plasticity

Nature

Volumn 460, Issue 7256, 2009, Pages 705-710

  Cordes, Kimberly R ^a,b   Sheehy, Neil T ^a,b   White, Mark P ^a,b   Berry, Emily C ^a,b   Morton, Sarah U ^a,b   Muth, Alecia N ^a,b   Lee, Ting Hein ^c   Miano, Joseph M ^c   Ivey, Kathryn N ^a,b   Srivastava, Deepak ^a,b  

^a GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

KRUPPEL LIKE FACTOR 4; MICRORNA; MYOCARDIN; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR NKX2.5;

CYTOLOGY; MUSCLE; PLASTICITY; RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CELL FATE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; MOUSE; NEURAL CREST CELL; NONHUMAN; PRIORITY JOURNAL; RNA TRANSCRIPTION; SMOOTH MUSCLE FIBER; STEM CELL; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; ETS-DOMAIN PROTEIN ELK-4; FEMALE; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; MALE; MICE; MICE, TRANSGENIC; MICRORNAS; MODELS, BIOLOGICAL; MYOCARDIUM; MYOCYTES, SMOOTH MUSCLE; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VASCULAR DISEASES;

MURINAE;

EID: 68449097267     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08195     Document Type: Article

References (42)

1. Kloosterman, W. P. & Plasterk, R. H. The diverse functions of microRNAs in anima development and disease. Dev. Cell 11, 441-450 (2006).
2. Calin, G. A. & Croce, C. M. MicroRNA signatures in human cancers. Nature Rev. Cancer 6, 857-866 (2006).
3. Zhao, Y. & Srivastava, D. A developmental view of microRNA function. Trends Biochem. Sci. 32, 189-197 (2007).
4. Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
5. Rajewsky, N. MicroRNA target predictions in animals. Nature Genet. 38(Suppl), S8-S13 (2006).
6. Vasudevan, S., Tong, Y. & Steitz, J. A. Switching from repression to activation: microRNAs can up-regulate translation. Science 318, 1931-1934 (2007).
7. Zhao, Y., Samal, E. & Srivastava, D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436, 214-220 (2005).
8. Kwon, C., Han, Z., Olson, E. N. & Srivastava, D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc. Natl Acad. Sci. USA 102, 18986-18991 (2005).
9. Chen, J. F. et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nature Genet. 38, 228-233 (2006).
10. Zhao, Y. et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell 129, 303-317 (2007).
11. Ivey, K. N. et al. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell 2, 219-229 (2008).
12. Srivastava, D. Making or breaking the heart: from lineage determination to morphogenesis. Cell 126, 1037-1048 (2006).
13. Kattman, S. J., Huber, T. L. & Keller, G. M. Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dev. Cell 11, 723-732 (2006).
14. Le Douarin, N. M., Creuzet, S., Couly, G. & Dupin, E. Neural crest cell plasticity and its limits. Development 131, 4637-4650 (2004).
15. Ross, R. The pathogenesis of atherosclerosis: A perspective for the 1990s. Nature 362, 801-809 (1993).
16. Owens, G. K., Kumar, M. S. & Wamhoff, B. R. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol. Rev. 84, 767-801 (2004).
17. Yoshida, T. & Owens, G. K. Molecular determinants of vascular smooth muscle cell diversity. Circ. Res. 96, 280-291 (2005).
18. Wang, Y., Medvid, R., Melton, C., Jaenisch, R. & Blelloch, R. DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nature Genet. 39, 380-385 (2007).
19. Cai, C. L. et al. Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev. Cell 5, 877-889 (2003).
20. Srinivas, S. et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 1, 4 (2001).
21. Moretti, A. et al. Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127, 1151-1165 (2006).
22. Wang, Z. et al. Myocardin and ternary complex factors compete for SRF to contro smooth muscle gene expression. Nature 428, 185-189 (2004).
23. Wang, D. et al. Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell 105, 851-862 (2001).
24. Chen, J., Kitchen, C. M., Streb, J. W. & Miano, J. M. Myocardin: a component of a molecular switch for smooth muscle differentiation. J. Mol. Cell. Cardiol. 34, 1345-1356 (2002).
25. Long, X., Bell, R. D., Gerthoffer, W. T., Zlokovic, B. V. & Miano, J. M. Myocardin is sufficient for a smooth muscle-like contractile phenotype. Arterioscler. Thromb. Vasc. Biol. 28, 1505-1510 (2008).
26. Chen, C. Y. & Schwartz, R. J. Recruitment of the tinman homolog Nkx-2.5 by serum response factor activates cardiac alpha-actin gene transcription. Mol. Cell. Biol. 16, 6372-6384 (1996).
27. Ji, R. et al. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ. Res. 100, 1579-1588 (2007).
28. Krutzfeldt, J. et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature 438, 685-689 (2005).
29. Maurer, J. et al. Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis. Differentiation 75, 580-591 (2007).
30. Takahashi, K. et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872 (2007).
31. Liu, Y. et al. Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. J. Biol. Chem. 280, 9719-9727 (2005).
32. House, S. J. & Singer, H. A. CaMKII-delta isoform regulation of neointima formation after vascular injury. Arterioscler. Thromb. Vasc. Biol. 28, 441-447 (2008).
33. 2+/calmodulin- dependent protein kinase II in vascular smooth muscle cells. Am. J. Pathol. 161, 1893-1901 (2002).
34. Xu, N., Papagiannakopoulos, T., Pan, G., Thomson, J. A. & Kosik, K. S. MicroRNA-145 regulates 0CT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 137, 647-658 (2009).
35. Yamagishi, H. et al. Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev. 17, 269-281 (2003).
36. Wang, Z., Wang, D. Z., Pipes, G. C. & Olson, E. N. Myocardin is a master regulator of smooth muscle gene expression. Proc. Natl Acad. Sci. USA 100, 7129-7134 (2003).
37. Yamamoto, M. et al. The roles of protein kinase C beta I and beta II in vascular smooth muscle cell proliferation. Exp. Cell Res. 240, 349-358 (1998).
38. Sinha, S. et al. Assessment of contractility of purified smooth muscle cells derived from embryonic stem cells. Stem Cells 24, 1678-1688 (2006).
39. Obernosterer, G., Martinez, J. & Alenius, M. Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nature Protocols 2, 1508-1514 (2007).
40. Kruger, J. & Rehmsmeier, M. RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Res. 34, W451-W454 (2006).
41. Zuker, M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31, 3406-3415 (2003).
42. Regan, C. P., Adam, P. J., Madsen, C. S. & Owens, G. K. Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury. J. Clin. Invest. 106, 1139-1147 (2000).