A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 20, 1999, Pages 11041-11048

  Brown, Michael S ^a   Goldstein, Joseph L ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Site 1 protease; Site 2 protease; Sterol regulatory element binding proteins; Sterol sensing domain; Transcription

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; AMINO ACID; CHOLESTEROL; COMPLEMENTARY DNA; DNA; ENZYME; FATTY ACID; FATTY ACID SYNTHASE; GERANYLTRANSFERASE; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; LEUCINE ZIPPER PROTEIN; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; METALLOPROTEINASE; PHOSPHOLIPID; PROTEASOME; PROTEINASE; REGULATOR PROTEIN; SERINE PROTEINASE; SQUALENE SYNTHASE; STEROL REGULATORY ELEMENT BINDING PROTEIN; SUBTILISIN; THERMOLYSIN; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; UNINDEXED DRUG;

AMINO TERMINAL SEQUENCE; BLOOD; CELL MEMBRANE; CHOLESTEROL SYNTHESIS; CONFERENCE PAPER; ENDOPLASMIC RETICULUM; GENE; GENETIC TRANSCRIPTION; HUMAN; IMMUNOPRECIPITATION; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SEQUENCE HOMOLOGY;

EID: 0033613147     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.20.11041     Document Type: Article

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