메뉴 건너뛰기




Volumn 300, Issue 1, 2004, Pages 109-120

Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation

Author keywords

Cell cycle; Cholesterol; Cyclins; Cytokinesis; Endoreplication

Indexed keywords

CHOLESTEROL; CYCLINE; LANOSTEROL DERIVATIVE; SKF 104976; STEROL 14ALPHA DEMETHYLASE;

EID: 4644372454     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.06.029     Document Type: Article
Times cited : (121)

References (47)
  • 1
    • 0011014154 scopus 로고
    • Relationship between sterol synthesis and DNA synthesis in phytohemagglutinin-stimulated mouse lymphocytes
    • H.W. Chen, H.J. Heiniger, and A.A. Kandutsch Relationship between sterol synthesis and DNA synthesis in phytohemagglutinin-stimulated mouse lymphocytes Proc. Natl. Acad. Sci.U. S. A. 72 1975 1950 1954
    • (1975) Proc. Natl. Acad. Sci.U. S. A. , vol.72 , pp. 1950-1954
    • Chen, H.W.1    Heiniger, H.J.2    Kandutsch, A.A.3
  • 2
    • 0016328910 scopus 로고
    • Inhibition of cell growth by oxygenated derivatives of cholesterol
    • H.W. Chen, A.A. Kandutsch, and C. Waymouth Inhibition of cell growth by oxygenated derivatives of cholesterol Nature 251 1974 419 421
    • (1974) Nature , vol.251 , pp. 419-421
    • Chen, H.W.1    Kandutsch, A.A.2    Waymouth, C.3
  • 3
    • 0016206178 scopus 로고
    • Suppression of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol
    • M.S. Brown, and J.L. Goldstein Suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and inhibition of growth of human fibroblasts by 7-ketocholesterol J. Biol. Chem. 249 1974 7306 7314
    • (1974) J. Biol. Chem. , vol.249 , pp. 7306-7314
    • Brown, M.S.1    Goldstein, J.L.2
  • 5
    • 0027971909 scopus 로고
    • Inhibition of protein farnesyltransferase: A possible mechanism of tumor prevention by dehydroepiandrosterone sulfate
    • S. Schulz, and J.W. Nyce Inhibition of protein farnesyltransferase: a possible mechanism of tumor prevention by dehydroepiandrosterone sulfate Carcinogenesis 15 1994 2649 2652
    • (1994) Carcinogenesis , vol.15 , pp. 2649-2652
    • Schulz, S.1    Nyce, J.W.2
  • 6
    • 0031568948 scopus 로고    scopus 로고
    • Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate
    • D.C. Crick, D.A. Andres, and C.J. Waechter Geranylgeraniol promotes entry of UT-2 cells into the cell cycle in the absence of mevalonate Exp. Cell Res. 231 1997 302 307
    • (1997) Exp. Cell Res. , vol.231 , pp. 302-307
    • Crick, D.C.1    Andres, D.A.2    Waechter, C.J.3
  • 7
    • 0029857638 scopus 로고    scopus 로고
    • Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts
    • A. Vogt, Y. Qian, T.F. McGuire, A.D. Hamilton, and S.M. Sebti Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts Oncogene 13 1996 1991 1999
    • (1996) Oncogene , vol.13 , pp. 1991-1999
    • Vogt, A.1    Qian, Y.2    McGuire, T.F.3    Hamilton, A.D.4    Sebti, S.M.5
  • 8
    • 0035967798 scopus 로고    scopus 로고
    • Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives
    • J. Martínez-Botas, A.J. Ferruelo, Y. Suárez, C. Fernández, D. Gómez-Coronado, and M.A. Lasunción Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives Biochim. Biophys. Acta 1532 2001 185 194
    • (2001) Biochim. Biophys. Acta , vol.1532 , pp. 185-194
    • Martínez-Botas, J.1    Ferruelo, A.J.2    Suárez, Y.3    Fernández, C.4    Gómez-Coronado, D.5    Lasunción, M.A.6
  • 9
    • 0029119740 scopus 로고
    • Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs)
    • X. Grana, and E.P. Reddy Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs) Oncogene 11 1995 211 219
    • (1995) Oncogene , vol.11 , pp. 211-219
    • Grana, X.1    Reddy, E.P.2
  • 10
    • 0242432371 scopus 로고    scopus 로고
    • Nobel Lecture. Cyclin dependent kinases and cell cycle control
    • P.M. Nurse Nobel Lecture. Cyclin dependent kinases and cell cycle control Biosci. Rep. 22 2002 487 499
    • (2002) Biosci. Rep. , vol.22 , pp. 487-499
    • Nurse, P.M.1
  • 12
    • 0024978344 scopus 로고
    • The role of cyclin synthesis and degradation in the control of maturation promoting factor activity
    • A.W. Murray, M.J. Solomon, and M.W. Kirschner The role of cyclin synthesis and degradation in the control of maturation promoting factor activity Nature 339 1989 280 286
    • (1989) Nature , vol.339 , pp. 280-286
    • Murray, A.W.1    Solomon, M.J.2    Kirschner, M.W.3
  • 13
    • 0024823053 scopus 로고
    • The mammalian cdc2 protein kinase: Mechanisms of regulation during the cell cycle
    • G. Draetta, and D. Beach The mammalian cdc2 protein kinase: mechanisms of regulation during the cell cycle J. Cell Sci., Suppl. 12 1989 21 27
    • (1989) J. Cell Sci., Suppl. , vol.12 , pp. 21-27
    • Draetta, G.1    Beach, D.2
  • 14
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: Cyclins revisited
    • A.W. Murray Recycling the cell cycle: cyclins revisited Cell 116 2004 221 234
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 15
    • 0032741063 scopus 로고    scopus 로고
    • Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulans
    • C. De, P. Souza, X.S. Ye, and S.A. Osmani Checkpoint defects leading to premature mitosis also cause endoreplication of DNA in Aspergillus nidulans Mol. Biol. Cell 10 1999 3661 3674
    • (1999) Mol. Biol. Cell , vol.10 , pp. 3661-3674
    • De, C.1    Souza, P.2    Ye, X.S.3    Osmani, S.A.4
  • 16
    • 0030038381 scopus 로고    scopus 로고
    • Novel alterations in CDK1/cyclin B1 kinase complex formation occur during the acquisition of a polyploid DNA content
    • N.S. Datta, J.L. Williams, J. Caldwell, A.M. Curry, E.K. Ashcraft, and M.W. Long Novel alterations in CDK1/cyclin B1 kinase complex formation occur during the acquisition of a polyploid DNA content Mol. Biol. Cell 7 1996 209 223
    • (1996) Mol. Biol. Cell , vol.7 , pp. 209-223
    • Datta, N.S.1    Williams, J.L.2    Caldwell, J.3    Curry, A.M.4    Ashcraft, E.K.5    Long, M.W.6
  • 17
    • 0025331088 scopus 로고
    • The roles of Drosophila cyclins a and B in mitotic control
    • C.F. Lehner, and P.H. O'Farrell The roles of Drosophila cyclins A and B in mitotic control Cell 61 1990 535 547
    • (1990) Cell , vol.61 , pp. 535-547
    • Lehner, C.F.1    O'Farrell, P.H.2
  • 18
    • 0031914641 scopus 로고    scopus 로고
    • Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes
    • Y. Zhang, Z. Wang, D.X. Liu, M. Pagano, and K. Ravid Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes J. Biol. Chem. 273 1998 1387 1392
    • (1998) J. Biol. Chem. , vol.273 , pp. 1387-1392
    • Zhang, Y.1    Wang, Z.2    Liu, D.X.3    Pagano, M.4    Ravid, K.5
  • 19
    • 0030044054 scopus 로고    scopus 로고
    • The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase
    • Y. Zhang, Z. Wang, and K. Ravid The cell cycle in polyploid megakaryocytes is associated with reduced activity of cyclin B1-dependent cdc2 kinase J. Biol. Chem. 271 1996 4266 4272
    • (1996) J. Biol. Chem. , vol.271 , pp. 4266-4272
    • Zhang, Y.1    Wang, Z.2    Ravid, K.3
  • 20
    • 0018377230 scopus 로고
    • Loss of centrioles and polyploidization in follicle cells of Drosophila melanogaster
    • A.P. Mahowald, J.H. Caulton, M.K. Edwards, and A.D. Floyd Loss of centrioles and polyploidization in follicle cells of Drosophila melanogaster Exp. Cell Res. 118 1979 404 410
    • (1979) Exp. Cell Res. , vol.118 , pp. 404-410
    • Mahowald, A.P.1    Caulton, J.H.2    Edwards, M.K.3    Floyd, A.D.4
  • 21
    • 0034640856 scopus 로고    scopus 로고
    • An essential role for a membrane lipid in cytokinesis. Regulation of contractile ring disassembly by redistribution of phosphatidylethanolamine
    • K. Emoto, and M. Umeda An essential role for a membrane lipid in cytokinesis. Regulation of contractile ring disassembly by redistribution of phosphatidylethanolamine J. Cell Biol. 149 2000 1215 1224
    • (2000) J. Cell Biol. , vol.149 , pp. 1215-1224
    • Emoto, K.1    Umeda, M.2
  • 22
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • J. Folch, M. Lees, G. Sloane, and H. Stanley A simple method for the isolation and purification of total lipides from animal tissues J. Biol. Chem. 226 1957 497 509
    • (1957) J. Biol. Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane, G.3    Stanley, H.4
  • 23
    • 0037103818 scopus 로고    scopus 로고
    • Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells
    • C. Fernández, Y. Suárez, A.J. Ferruelo, D. Gómez-Coronado, and M.A. Lasunción Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells Biochem. J. 366 2002 109 119
    • (2002) Biochem. J. , vol.366 , pp. 109-119
    • Fernández, C.1    Suárez, Y.2    Ferruelo, A.J.3    Gómez-Coronado, D.4    Lasunción, M.A.5
  • 25
    • 0028694727 scopus 로고
    • Analysis of DNA content and cyclin protein expression in studies of DNA ploidy, growth fraction, lymphocyte stimulation, and the cell cycle
    • Z. Darzynkiewicz, J. Gong, and F. Traganos Analysis of DNA content and cyclin protein expression in studies of DNA ploidy, growth fraction, lymphocyte stimulation, and the cell cycle Methods Cell Biol. 41 1994 421 435
    • (1994) Methods Cell Biol. , vol.41 , pp. 421-435
    • Darzynkiewicz, Z.1    Gong, J.2    Traganos, F.3
  • 27
    • 0028978778 scopus 로고
    • Discrimination of G2 and mitotic cells by flow cytometry based on different expression of cyclins a and B1
    • J. Gong, F. Traganos, and Z. Darzynkiewicz Discrimination of G2 and mitotic cells by flow cytometry based on different expression of cyclins A and B1 Exp. Cell Res. 220 1995 226 231
    • (1995) Exp. Cell Res. , vol.220 , pp. 226-231
    • Gong, J.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 28
    • 0028328492 scopus 로고
    • Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis
    • F. Traganos, J. Gong, B. Ardelt, and Z. Darzynkiewicz Effect of staurosporine on MOLT-4 cell progression through G2 and on cytokinesis J. Cell. Physiol. 158 1994 535 544
    • (1994) J. Cell. Physiol. , vol.158 , pp. 535-544
    • Traganos, F.1    Gong, J.2    Ardelt, B.3    Darzynkiewicz, Z.4
  • 29
    • 0027448532 scopus 로고
    • Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements
    • J. Gong, F. Traganos, and Z. Darzynkiewicz Simultaneous analysis of cell cycle kinetics at two different DNA ploidy levels based on DNA content and cyclin B measurements Cancer Res. 53 1993 5096 5099
    • (1993) Cancer Res. , vol.53 , pp. 5096-5099
    • Gong, J.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 30
    • 0029127853 scopus 로고
    • Threshold expression of cyclin e but not D type cyclins characterizes normal and tumour cells entering S phase
    • J. Gong, F. Traganos, and Z. Darzynkiewicz Threshold expression of cyclin E but not D type cyclins characterizes normal and tumour cells entering S phase Cell Proliferation 28 1995 337 346
    • (1995) Cell Proliferation , vol.28 , pp. 337-346
    • Gong, J.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 32
    • 0026039147 scopus 로고
    • Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin
    • K. Keyomarsi, L. Sandoval, V. Band, and A.B. Pardee Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin Cancer Res. 51 1991 3602 3609
    • (1991) Cancer Res. , vol.51 , pp. 3602-3609
    • Keyomarsi, K.1    Sandoval, L.2    Band, V.3    Pardee, A.B.4
  • 34
    • 0025916883 scopus 로고
    • Interrelationships between mevalonate metabolism and the mitogenic signaling pathway in T lymphocyte proliferation
    • R. Chakrabarti, and E.G. Engleman Interrelationships between mevalonate metabolism and the mitogenic signaling pathway in T lymphocyte proliferation J. Biol. Chem. 266 1991 12216 12222
    • (1991) J. Biol. Chem. , vol.266 , pp. 12216-12222
    • Chakrabarti, R.1    Engleman, E.G.2
  • 36
    • 0023871216 scopus 로고
    • A mammalian mutant cell lacking detectable lanosterol 14 alpha-methyl demethylase activity
    • H.W. Chen, D.A. Leonard, R.T. Fischer, and J.M. Trzaskos A mammalian mutant cell lacking detectable lanosterol 14 alpha-methyl demethylase activity J. Biol. Chem. 263 1988 1248 1254
    • (1988) J. Biol. Chem. , vol.263 , pp. 1248-1254
    • Chen, H.W.1    Leonard, D.A.2    Fischer, R.T.3    Trzaskos, J.M.4
  • 37
    • 0035936920 scopus 로고    scopus 로고
    • Centrosome-dependent exit of cytokinesis in animal cells
    • M. Piel, J. Nordberg, U. Euteneuer, and M. Bornens Centrosome-dependent exit of cytokinesis in animal cells Science 291 2001 1550 1553
    • (2001) Science , vol.291 , pp. 1550-1553
    • Piel, M.1    Nordberg, J.2    Euteneuer, U.3    Bornens, M.4
  • 38
    • 0035805201 scopus 로고    scopus 로고
    • Endoreplication cell cycles: More for less
    • B.A. Edgar, and T.L. Orr-Weaver Endoreplication cell cycles: more for less Cell 105 2001 297 306
    • (2001) Cell , vol.105 , pp. 297-306
    • Edgar, B.A.1    Orr-Weaver, T.L.2
  • 39
    • 0031037222 scopus 로고    scopus 로고
    • Construction by gene targeting in human cells of a " conditional" CDC2 mutant that rereplicates its DNA
    • J.E. Itzhaki, C.S. Gilbert, and A.C. Porter Construction by gene targeting in human cells of a "conditional" CDC2 mutant that rereplicates its DNA Nat. Genet. 15 1997 258 265
    • (1997) Nat. Genet. , vol.15 , pp. 258-265
    • Itzhaki, J.E.1    Gilbert, C.S.2    Porter, A.C.3
  • 40
    • 0035963318 scopus 로고    scopus 로고
    • Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: Induction of endoreplication following prophase arrest
    • E. Damiens, B. Baratte, D. Marie, G. Eisenbrand, and L. Meijer Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest Oncogene 20 2001 3786 3797
    • (2001) Oncogene , vol.20 , pp. 3786-3797
    • Damiens, E.1    Baratte, B.2    Marie, D.3    Eisenbrand, G.4    Meijer, L.5
  • 42
    • 0032851461 scopus 로고    scopus 로고
    • Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole
    • B. Verdoodt, I. Decordier, K. Geleyns, M. Cunha, E. Cundari, and M. Kirsch-Volders Induction of polyploidy and apoptosis after exposure to high concentrations of the spindle poison nocodazole Mutagenesis 14 1999 513 520
    • (1999) Mutagenesis , vol.14 , pp. 513-520
    • Verdoodt, B.1    Decordier, I.2    Geleyns, K.3    Cunha, M.4    Cundari, E.5    Kirsch-Volders, M.6
  • 43
    • 0035418188 scopus 로고    scopus 로고
    • Inverse regulation of cyclin B1 by c-Myc and p53 and induction of tetraploidy by cyclin B1 overexpression
    • X.Y. Yin, L. Grove, N.S. Datta, K. Katula, M.W. Long, and E.V. Prochownik Inverse regulation of cyclin B1 by c-Myc and p53 and induction of tetraploidy by cyclin B1 overexpression Cancer Res. 61 2001 6487 6493
    • (2001) Cancer Res. , vol.61 , pp. 6487-6493
    • Yin, X.Y.1    Grove, L.2    Datta, N.S.3    Katula, K.4    Long, M.W.5    Prochownik, E.V.6
  • 44
    • 0026801977 scopus 로고
    • Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
    • Y. Yin, M.A. Tainsky, F.Z. Bischoff, L.C. Strong, and G.M. Wahl Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles Cell 70 1992 937 948
    • (1992) Cell , vol.70 , pp. 937-948
    • Yin, Y.1    Tainsky, M.A.2    Bischoff, F.Z.3    Strong, L.C.4    Wahl, G.M.5
  • 46
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • T. Waldman, C. Lengauer, K.W. Kinzler, and B. Vogelstein Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 Nature 381 1996 713 716
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 47
    • 0001606206 scopus 로고
    • Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells
    • D. Wolf, and V. Rotter Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells Proc. Natl. Acad. Sci. U. S. A. 82 1985 790 794
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 790-794
    • Wolf, D.1    Rotter, V.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.