-
1
-
-
15544369658
-
Host-bacterial mutualism in the human intestine
-
Backhed F., Ley R.E., Sonnenburg J.L., Peterson D.A., Gordon J.I. Host-bacterial mutualism in the human intestine. Science 2005, 307:1915-1920.
-
(2005)
Science
, vol.307
, pp. 1915-1920
-
-
Backhed, F.1
Ley, R.E.2
Sonnenburg, J.L.3
Peterson, D.A.4
Gordon, J.I.5
-
2
-
-
77950353786
-
Homeostasis and inflammation in the intestine
-
Garrett W.S., Gordon J.I., Glimcher L.H. Homeostasis and inflammation in the intestine. Cell 2010, 140:859-870.
-
(2010)
Cell
, vol.140
, pp. 859-870
-
-
Garrett, W.S.1
Gordon, J.I.2
Glimcher, L.H.3
-
3
-
-
77954607064
-
A pathobiont of the microbiota balances host colonization and intestinal inflammation
-
Chow J., Mazmanian S.K. A pathobiont of the microbiota balances host colonization and intestinal inflammation. Cell Host Microbe 2010, 7:265-276.
-
(2010)
Cell Host Microbe
, vol.7
, pp. 265-276
-
-
Chow, J.1
Mazmanian, S.K.2
-
4
-
-
0345830652
-
Dysbiosis in inflammatory bowel disease
-
Tamboli C.P., Neut C., Desreumaux P., Colombel J.F. Dysbiosis in inflammatory bowel disease. Gut 2004, 53:1-4.
-
(2004)
Gut
, vol.53
, pp. 1-4
-
-
Tamboli, C.P.1
Neut, C.2
Desreumaux, P.3
Colombel, J.F.4
-
5
-
-
77952318832
-
Intestinal bacteria and the regulation of immune cell homeostasis
-
Hill D.A., Artis D. Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol 2010, 28:623-667.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 623-667
-
-
Hill, D.A.1
Artis, D.2
-
6
-
-
78650647326
-
Has the microbiota played a critical role in the evolution of the adaptive immune system?
-
Lee Y.K., Mazmanian S.K. Has the microbiota played a critical role in the evolution of the adaptive immune system?. Science 2010, 330:1768-1773.
-
(2010)
Science
, vol.330
, pp. 1768-1773
-
-
Lee, Y.K.1
Mazmanian, S.K.2
-
7
-
-
34848889673
-
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
-
Garrett W.S., Lord G.M., Punit S., Lugo-Villarino G., Mazmanian S.K., Ito S., et al. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system. Cell 2007, 131:33-45.
-
(2007)
Cell
, vol.131
, pp. 33-45
-
-
Garrett, W.S.1
Lord, G.M.2
Punit, S.3
Lugo-Villarino, G.4
Mazmanian, S.K.5
Ito, S.6
-
8
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav E., Strowig T., Kau A.L., Henao-Mejia J., Thaiss C.A., Booth C.J., et al. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 2011, 145:745-757.
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
-
9
-
-
0037136537
-
The effect of infections on susceptibility to autoimmune and allergic diseases
-
Bach J.F. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002, 347:911-920.
-
(2002)
N Engl J Med
, vol.347
, pp. 911-920
-
-
Bach, J.F.1
-
10
-
-
77953913586
-
Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells
-
Wu H.J., Ivanov I.I., Darce J., Hattori K., Shima T., Umesaki Y., et al. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity 2010, 32:815-827.
-
(2010)
Immunity
, vol.32
, pp. 815-827
-
-
Wu, H.J.1
Ivanov, I.I.2
Darce, J.3
Hattori, K.4
Shima, T.5
Umesaki, Y.6
-
11
-
-
79952748674
-
Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
-
Lee Y.K., Menezes J.S., Umesaki Y., Mazmanian S.K. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2011, 108(Suppl. 1):4615-4622.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.SUPPL. 1
, pp. 4615-4622
-
-
Lee, Y.K.1
Menezes, J.S.2
Umesaki, Y.3
Mazmanian, S.K.4
-
12
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
-
Wen L., Ley R.E., Volchkov P.Y., Stranges P.B., Avanesyan L., Stonebraker A.C., et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 2008, 455:1109-1113.
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
Ley, R.E.2
Volchkov, P.Y.3
Stranges, P.B.4
Avanesyan, L.5
Stonebraker, A.C.6
-
13
-
-
56749146467
-
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
-
Bouskra D., Brezillon C., Berard M., Werts C., Varona R., Boneca I.G., et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 2008, 456:507-510.
-
(2008)
Nature
, vol.456
, pp. 507-510
-
-
Bouskra, D.1
Brezillon, C.2
Berard, M.3
Werts, C.4
Varona, R.5
Boneca, I.G.6
-
14
-
-
57849117363
-
RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
-
Sanos S.L., Bui V.L., Mortha A., Oberle K., Heners C., Johner C., et al. RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat Immunol 2009, 10:83-91.
-
(2009)
Nat Immunol
, vol.10
, pp. 83-91
-
-
Sanos, S.L.1
Bui, V.L.2
Mortha, A.3
Oberle, K.4
Heners, C.5
Johner, C.6
-
15
-
-
80052966918
-
IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium
-
Ota N., Wong K., Valdez P.A., Zheng Y., Crellin N.K., Diehl L., et al. IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium. Nat Immunol 2011, 12:941-948.
-
(2011)
Nat Immunol
, vol.12
, pp. 941-948
-
-
Ota, N.1
Wong, K.2
Valdez, P.A.3
Zheng, Y.4
Crellin, N.K.5
Diehl, L.6
-
16
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
Ivanov I.I., Atarashi K., Manel N., Brodie E.L., Shima T., Karaoz U., et al. Induction of intestinal Th17 cells by segmented filamentous bacteria. Cell 2009, 139:485-498.
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
Atarashi, K.2
Manel, N.3
Brodie, E.L.4
Shima, T.5
Karaoz, U.6
-
17
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
Atarashi K., Tanoue T., Shima T., Imaoka A., Kuwahara T., Momose Y., et al. Induction of colonic regulatory T cells by indigenous Clostridium species. Science 2011, 331:337-341.
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
Imaoka, A.4
Kuwahara, T.5
Momose, Y.6
-
18
-
-
67349250428
-
The gut microbiota shapes intestinal immune responses during health and disease
-
Round J.L., Mazmanian S.K. The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 2009, 9:313-323.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 313-323
-
-
Round, J.L.1
Mazmanian, S.K.2
-
19
-
-
70349742524
-
The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses
-
Gaboriau-Routhiau V., Rakotobe S., Lecuyer E., Mulder I., Lan A., Bridonneau C., et al. The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses. Immunity 2009, 31:677-689.
-
(2009)
Immunity
, vol.31
, pp. 677-689
-
-
Gaboriau-Routhiau, V.1
Rakotobe, S.2
Lecuyer, E.3
Mulder, I.4
Lan, A.5
Bridonneau, C.6
-
20
-
-
79960983258
-
Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice
-
Kriegel M.A., Sefik E., Hill J.A., Wu H.J., Benoist C., Mathis D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc Natl Acad Sci U S A 2011, 108:11548-11553.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11548-11553
-
-
Kriegel, M.A.1
Sefik, E.2
Hill, J.A.3
Wu, H.J.4
Benoist, C.5
Mathis, D.6
-
21
-
-
79956311926
-
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
-
Round J.L., Lee S.M., Li J., Tran G., Jabri B., Chatila T.A., et al. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 2011, 332:974-977.
-
(2011)
Science
, vol.332
, pp. 974-977
-
-
Round, J.L.1
Lee, S.M.2
Li, J.3
Tran, G.4
Jabri, B.5
Chatila, T.A.6
-
22
-
-
77954738601
-
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
-
Round J.L., Mazmanian S.K. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci U S A 2010, 107:12204-12209.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12204-12209
-
-
Round, J.L.1
Mazmanian, S.K.2
-
23
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot J.D., Gavin M.A., Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 2003, 4:330-336.
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
24
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila T.A., Blaeser F., Ho N., Lederman H.M., Voulgaropoulos C., Helms C., et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000, 106:R75-R81.
-
(2000)
J Clin Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
-
25
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
26
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing K., Onishi Y., Prieto-Martin P., Yamaguchi T., Miyara M., Fehervari Z., et al. CTLA-4 control over Foxp3+ regulatory T cell function. Science 2008, 322:271-275.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
-
27
-
-
36248976097
-
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
-
Pandiyan P., Zheng L., Ishihara S., Reed J., Lenardo M.J. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol 2007, 8:1353-1362.
-
(2007)
Nat Immunol
, vol.8
, pp. 1353-1362
-
-
Pandiyan, P.1
Zheng, L.2
Ishihara, S.3
Reed, J.4
Lenardo, M.J.5
-
28
-
-
48249103057
-
Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
-
Onishi Y., Fehervari Z., Yamaguchi T., Sakaguchi S. Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc Natl Acad Sci U S A 2008, 105:10113-10118.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10113-10118
-
-
Onishi, Y.1
Fehervari, Z.2
Yamaguchi, T.3
Sakaguchi, S.4
-
29
-
-
65749103365
-
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
-
Koch M.A., Tucker-Heard G., Perdue N.R., Killebrew J.R., Urdahl K.B., Campbell D.J. The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation. Nat Immunol 2009, 10:595-602.
-
(2009)
Nat Immunol
, vol.10
, pp. 595-602
-
-
Koch, M.A.1
Tucker-Heard, G.2
Perdue, N.R.3
Killebrew, J.R.4
Urdahl, K.B.5
Campbell, D.J.6
-
30
-
-
62649165369
-
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses
-
Zheng Y., Chaudhry A., Kas A., deRoos P., Kim J.M., Chu T.T., et al. Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responses. Nature 2009, 458:351-356.
-
(2009)
Nature
, vol.458
, pp. 351-356
-
-
Zheng, Y.1
Chaudhry, A.2
Kas, A.3
deRoos, P.4
Kim, J.M.5
Chu, T.T.6
-
31
-
-
70049113279
-
CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner
-
Chaudhry A., Rudra D., Treuting P., Samstein R.M., Liang Y., Kas A., et al. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner. Science 2009, 326:986-991.
-
(2009)
Science
, vol.326
, pp. 986-991
-
-
Chaudhry, A.1
Rudra, D.2
Treuting, P.3
Samstein, R.M.4
Liang, Y.5
Kas, A.6
-
32
-
-
33746377279
-
Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation
-
Izcue A., Coombes J.L., Powrie F. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol Rev 2006, 212:256-271.
-
(2006)
Immunol Rev
, vol.212
, pp. 256-271
-
-
Izcue, A.1
Coombes, J.L.2
Powrie, F.3
-
33
-
-
70049098536
-
Regulatory T cells reinforce intestinal homeostasis
-
Barnes M.J., Powrie F. Regulatory T cells reinforce intestinal homeostasis. Immunity 2009, 31:401-411.
-
(2009)
Immunity
, vol.31
, pp. 401-411
-
-
Barnes, M.J.1
Powrie, F.2
-
34
-
-
0037243827
-
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
-
Maloy K.J., Salaun L., Cahill R., Dougan G., Saunders N.J., Powrie F. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med 2003, 197:111-119.
-
(2003)
J Exp Med
, vol.197
, pp. 111-119
-
-
Maloy, K.J.1
Salaun, L.2
Cahill, R.3
Dougan, G.4
Saunders, N.J.5
Powrie, F.6
-
35
-
-
26844450449
-
How defects in central tolerance impinge on a deficiency in regulatory T cells
-
Chen Z., Benoist C., Mathis D. How defects in central tolerance impinge on a deficiency in regulatory T cells. Proc Natl Acad Sci U S A 2005, 102:14735-14740.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 14735-14740
-
-
Chen, Z.1
Benoist, C.2
Mathis, D.3
-
36
-
-
0038434099
-
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
-
Gambineri E., Torgerson T.R., Ochs H.D. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr Opin Rheumatol 2003, 15:430-435.
-
(2003)
Curr Opin Rheumatol
, vol.15
, pp. 430-435
-
-
Gambineri, E.1
Torgerson, T.R.2
Ochs, H.D.3
-
37
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
-
Bennett C.L., Christie J., Ramsdell F., Brunkow M.E., Ferguson P.J., Whitesell L., et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001, 27:20-21.
-
(2001)
Nat Genet
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
Christie, J.2
Ramsdell, F.3
Brunkow, M.E.4
Ferguson, P.J.5
Whitesell, L.6
-
38
-
-
0242407709
-
Transcription factors in autoimmunity
-
Ramsdell F., Ziegler S.F. Transcription factors in autoimmunity. Curr Opin Immunol 2003, 15:718-724.
-
(2003)
Curr Opin Immunol
, vol.15
, pp. 718-724
-
-
Ramsdell, F.1
Ziegler, S.F.2
-
39
-
-
55049111426
-
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke A., Balschun T., Karlsen T.H., Sventoraityte J., Nikolaus S., Mayr G., et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 2008, 40:1319-1323.
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
Mayr, G.6
-
40
-
-
0028519015
-
Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells
-
Powrie F., Leach M.W., Mauze S., Menon S., Caddle L.B., Coffman R.L. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. Immunity 1994, 1:553-562.
-
(1994)
Immunity
, vol.1
, pp. 553-562
-
-
Powrie, F.1
Leach, M.W.2
Mauze, S.3
Menon, S.4
Caddle, L.B.5
Coffman, R.L.6
-
41
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R., Lohler J., Rennick D., Rajewsky K., Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 1993, 75:263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
42
-
-
0032425062
-
Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism
-
Kullberg M.C., Ward J.M., Gorelick P.L., Caspar P., Hieny S., Cheever A., et al. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infect Immun 1998, 66:5157-5166.
-
(1998)
Infect Immun
, vol.66
, pp. 5157-5166
-
-
Kullberg, M.C.1
Ward, J.M.2
Gorelick, P.L.3
Caspar, P.4
Hieny, S.5
Cheever, A.6
-
43
-
-
9244237038
-
T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation
-
Roers A., Siewe L., Strittmatter E., Deckert M., Schluter D., Stenzel W., et al. T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation. J Exp Med 2004, 200:1289-1297.
-
(2004)
J Exp Med
, vol.200
, pp. 1289-1297
-
-
Roers, A.1
Siewe, L.2
Strittmatter, E.3
Deckert, M.4
Schluter, D.5
Stenzel, W.6
-
44
-
-
41549159660
-
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
-
Rubtsov Y.P., Rasmussen J.P., Chi E.Y., Fontenot J., Castelli L., Ye X., et al. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 2008, 28:546-558.
-
(2008)
Immunity
, vol.28
, pp. 546-558
-
-
Rubtsov, Y.P.1
Rasmussen, J.P.2
Chi, E.Y.3
Fontenot, J.4
Castelli, L.5
Ye, X.6
-
45
-
-
70949087383
-
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
-
Glocker E.O., Kotlarz D., Boztug K., Gertz E.M., Schaffer A.A., Noyan F., et al. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N Engl J Med 2009, 361:2033-2045.
-
(2009)
N Engl J Med
, vol.361
, pp. 2033-2045
-
-
Glocker, E.O.1
Kotlarz, D.2
Boztug, K.3
Gertz, E.M.4
Schaffer, A.A.5
Noyan, F.6
-
46
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda K., Clausen B.E., Kaisho T., Tsujimura T., Terada N., Forster I., et al. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 1999, 10:39-49.
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
Tsujimura, T.4
Terada, N.5
Forster, I.6
-
47
-
-
78650209225
-
T regulatory cells maintain intestinal homeostasis by suppressing gammadelta T cells
-
Park S.G., Mathur R., Long M., Hosh N., Hao L., Hayden M.S., et al. T regulatory cells maintain intestinal homeostasis by suppressing gammadelta T cells. Immunity 2010, 33:791-803.
-
(2010)
Immunity
, vol.33
, pp. 791-803
-
-
Park, S.G.1
Mathur, R.2
Long, M.3
Hosh, N.4
Hao, L.5
Hayden, M.S.6
-
48
-
-
79954608612
-
Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation
-
Chaudhry A., Samstein R.M., Treuting P., Liang Y., Pils M.C., Heinrich J.M., et al. Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation. Immunity 2011, 34:566-578.
-
(2011)
Immunity
, vol.34
, pp. 566-578
-
-
Chaudhry, A.1
Samstein, R.M.2
Treuting, P.3
Liang, Y.4
Pils, M.C.5
Heinrich, J.M.6
-
49
-
-
79954620910
-
Th17 cells express interleukin-10 receptor and are controlled by Foxp3 and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner
-
Huber S., Gagliani N., Esplugues E., O'Connor W., Huber F.J., Chaudhry A., et al. Th17 cells express interleukin-10 receptor and are controlled by Foxp3 and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity 2011, 34:554-565.
-
(2011)
Immunity
, vol.34
, pp. 554-565
-
-
Huber, S.1
Gagliani, N.2
Esplugues, E.3
O'Connor, W.4
Huber, F.J.5
Chaudhry, A.6
-
50
-
-
34548131112
-
Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10
-
Maynard C.L., Harrington L.E., Janowski K.M., Oliver J.R., Zindl C.L., Rudensky A.Y., et al. Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10. Nat Immunol 2007, 8:931-941.
-
(2007)
Nat Immunol
, vol.8
, pp. 931-941
-
-
Maynard, C.L.1
Harrington, L.E.2
Janowski, K.M.3
Oliver, J.R.4
Zindl, C.L.5
Rudensky, A.Y.6
-
51
-
-
69249083836
-
Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
-
Pot C., Jin H., Awasthi A., Liu S.M., Lai C.Y., Madan R., et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J Immunol 2009, 183:797-801.
-
(2009)
J Immunol
, vol.183
, pp. 797-801
-
-
Pot, C.1
Jin, H.2
Awasthi, A.3
Liu, S.M.4
Lai, C.Y.5
Madan, R.6
-
52
-
-
77955903212
-
The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27
-
Apetoh L., Quintana F.J., Pot C., Joller N., Xiao S., Kumar D., et al. The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27. Nat Immunol 2010, 11:854-861.
-
(2010)
Nat Immunol
, vol.11
, pp. 854-861
-
-
Apetoh, L.1
Quintana, F.J.2
Pot, C.3
Joller, N.4
Xiao, S.5
Kumar, D.6
-
53
-
-
79952955744
-
The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
-
Cretney E., Xin A., Shi W., Minnich M., Masson F., Miasari M., et al. The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat Immunol 2011, 12:304-311.
-
(2011)
Nat Immunol
, vol.12
, pp. 304-311
-
-
Cretney, E.1
Xin, A.2
Shi, W.3
Minnich, M.4
Masson, F.5
Miasari, M.6
-
54
-
-
0029956024
-
A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells
-
Powrie F., Carlino J., Leach M.W., Mauze S., Coffman R.L. A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells. J Exp Med 1996, 183:2669-2674.
-
(1996)
J Exp Med
, vol.183
, pp. 2669-2674
-
-
Powrie, F.1
Carlino, J.2
Leach, M.W.3
Mauze, S.4
Coffman, R.L.5
-
55
-
-
0034679567
-
Cytotoxic T Lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S., Malmstrom V., Powrie F., Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 2000, 192:295-302.
-
(2000)
J Exp Med
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
56
-
-
34248592104
-
T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation
-
Li M.O., Wan Y.Y., Flavell R.A. T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity 2007, 26:579-591.
-
(2007)
Immunity
, vol.26
, pp. 579-591
-
-
Li, M.O.1
Wan, Y.Y.2
Flavell, R.A.3
-
57
-
-
15444363794
-
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells
-
Fahlen L., Read S., Gorelik L., Hurst S.D., Coffman R.L., Flavell R.A., et al. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med 2005, 201:737-746.
-
(2005)
J Exp Med
, vol.201
, pp. 737-746
-
-
Fahlen, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
-
58
-
-
36549030784
-
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
-
Collison L.W., Workman C.J., Kuo T.T., Boyd K., Wang Y., Vignali K.M., et al. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 2007, 450:566-569.
-
(2007)
Nature
, vol.450
, pp. 566-569
-
-
Collison, L.W.1
Workman, C.J.2
Kuo, T.T.3
Boyd, K.4
Wang, Y.5
Vignali, K.M.6
-
59
-
-
0033730056
-
Animal models of autoimmunity and their relevance to human diseases
-
Sakaguchi S. Animal models of autoimmunity and their relevance to human diseases. Curr Opin Immunol 2000, 12:684-690.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 684-690
-
-
Sakaguchi, S.1
-
60
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
Fontenot J.D., Rasmussen J.P., Williams L.M., Dooley J.L., Farr A.G., Rudensky A.Y. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005, 22:329-341.
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
61
-
-
31344480633
-
LAT-mediated signaling in CD4+CD25+ regulatory T cell development
-
Koonpaew S., Shen S., Flowers L., Zhang W. LAT-mediated signaling in CD4+CD25+ regulatory T cell development. J Exp Med 2006, 203:119-129.
-
(2006)
J Exp Med
, vol.203
, pp. 119-129
-
-
Koonpaew, S.1
Shen, S.2
Flowers, L.3
Zhang, W.4
-
62
-
-
0036669298
-
CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
-
Malek T.R., Yu A., Vincek V., Scibelli P., Kong L. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity 2002, 17:167-178.
-
(2002)
Immunity
, vol.17
, pp. 167-178
-
-
Malek, T.R.1
Yu, A.2
Vincek, V.3
Scibelli, P.4
Kong, L.5
-
63
-
-
7144259082
-
Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency
-
Papiernik M., de Moraes M.L., Pontoux C., Vasseur F., Penit C. Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency. Int Immunol 1998, 10:371-378.
-
(1998)
Int Immunol
, vol.10
, pp. 371-378
-
-
Papiernik, M.1
de Moraes, M.L.2
Pontoux, C.3
Vasseur, F.4
Penit, C.5
-
64
-
-
0036839102
-
Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers
-
Almeida A.R., Legrand N., Papiernik M., Freitas A.A. Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers. J Immunol 2002, 169:4850-4860.
-
(2002)
J Immunol
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
65
-
-
15444374646
-
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
-
Setoguchi R., Hori S., Takahashi T., Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 2005, 201:723-735.
-
(2005)
J Exp Med
, vol.201
, pp. 723-735
-
-
Setoguchi, R.1
Hori, S.2
Takahashi, T.3
Sakaguchi, S.4
-
66
-
-
33845935950
-
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells
-
Burchill M.A., Yang J., Vogtenhuber C., Blazar B.R., Farrar M.A. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J Immunol 2007, 178:280-290.
-
(2007)
J Immunol
, vol.178
, pp. 280-290
-
-
Burchill, M.A.1
Yang, J.2
Vogtenhuber, C.3
Blazar, B.R.4
Farrar, M.A.5
-
67
-
-
54349086262
-
Differential requirement of PKC-theta in the development and function of natural regulatory T cells
-
Gupta S., Manicassamy S., Vasu C., Kumar A., Shang W., Sun Z. Differential requirement of PKC-theta in the development and function of natural regulatory T cells. Mol Immunol 2008, 46:213-224.
-
(2008)
Mol Immunol
, vol.46
, pp. 213-224
-
-
Gupta, S.1
Manicassamy, S.2
Vasu, C.3
Kumar, A.4
Shang, W.5
Sun, Z.6
-
68
-
-
65549114796
-
Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery
-
Barnes M.J., Krebs P., Harris N., Eidenschenk C., Gonzalez-Quintial R., Arnold C.N., et al. Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery. PLoS Biol 2009, 7:e51.
-
(2009)
PLoS Biol
, vol.7
-
-
Barnes, M.J.1
Krebs, P.2
Harris, N.3
Eidenschenk, C.4
Gonzalez-Quintial, R.5
Arnold, C.N.6
-
69
-
-
65549146581
-
CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells
-
Molinero L.L., Yang J., Gajewski T., Abraham C., Farrar M.A., Alegre M.L. CARMA1 controls an early checkpoint in the thymic development of FoxP3+ regulatory T cells. J Immunol 2009, 182:6736-6743.
-
(2009)
J Immunol
, vol.182
, pp. 6736-6743
-
-
Molinero, L.L.1
Yang, J.2
Gajewski, T.3
Abraham, C.4
Farrar, M.A.5
Alegre, M.L.6
-
70
-
-
60549113390
-
Differential requirement for CARMA1 in agonist-selected T-cell development
-
Medoff B.D., Sandall B.P., Landry A., Nagahama K., Mizoguchi A., Luster A.D., et al. Differential requirement for CARMA1 in agonist-selected T-cell development. Eur J Immunol 2009, 39:78-84.
-
(2009)
Eur J Immunol
, vol.39
, pp. 78-84
-
-
Medoff, B.D.1
Sandall, B.P.2
Landry, A.3
Nagahama, K.4
Mizoguchi, A.5
Luster, A.D.6
-
71
-
-
0141678951
-
Mature T cells depend on signaling through the IKK complex
-
Schmidt-Supprian M., Courtois G., Tian J., Coyle A.J., Israel A., Rajewsky K., et al. Mature T cells depend on signaling through the IKK complex. Immunity 2003, 19:377-389.
-
(2003)
Immunity
, vol.19
, pp. 377-389
-
-
Schmidt-Supprian, M.1
Courtois, G.2
Tian, J.3
Coyle, A.J.4
Israel, A.5
Rajewsky, K.6
-
72
-
-
33748999526
-
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells
-
Sato S., Sanjo H., Tsujimura T., Ninomiya-Tsuji J., Yamamoto M., Kawai T., et al. TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells. Int Immunol 2006, 18:1405-1411.
-
(2006)
Int Immunol
, vol.18
, pp. 1405-1411
-
-
Sato, S.1
Sanjo, H.2
Tsujimura, T.3
Ninomiya-Tsuji, J.4
Yamamoto, M.5
Kawai, T.6
-
73
-
-
33746111852
-
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
-
Wan Y.Y., Chi H., Xie M., Schneider M.D., Flavell R.A. The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. Nat Immunol 2006, 7:851-858.
-
(2006)
Nat Immunol
, vol.7
, pp. 851-858
-
-
Wan, Y.Y.1
Chi, H.2
Xie, M.3
Schneider, M.D.4
Flavell, R.A.5
-
74
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
-
Zheng Y., Josefowicz S., Chaudhry A., Peng X.P., Forbush K., Rudensky A.Y. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 2010, 463:808-812.
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
75
-
-
34447503805
-
Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid
-
Mucida D., Park Y., Kim G., Turovskaya O., Scott I., Kronenberg M., et al. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007, 317:256-260.
-
(2007)
Science
, vol.317
, pp. 256-260
-
-
Mucida, D.1
Park, Y.2
Kim, G.3
Turovskaya, O.4
Scott, I.5
Kronenberg, M.6
-
76
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
-
Coombes J.L., Siddiqui K.R., Arancibia-Carcamo C.V., Hall J., Sun C.M., Belkaid Y., et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med 2007, 204:1757-1764.
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Carcamo, C.V.3
Hall, J.4
Sun, C.M.5
Belkaid, Y.6
-
77
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
-
Sun C.M., Hall J.A., Blank R.B., Bouladoux N., Oukka M., Mora J.R., et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med 2007, 204:1775-1785.
-
(2007)
J Exp Med
, vol.204
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
Bouladoux, N.4
Oukka, M.5
Mora, J.R.6
-
78
-
-
0348223787
-
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003, 198:1875-1886.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.J.4
Li, L.5
Marinos, N.6
-
79
-
-
38349095578
-
Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer
-
Tone Y., Furuuchi K., Kojima Y., Tykocinski M.L., Greene M.I., Tone M. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol 2008, 9:194-202.
-
(2008)
Nat Immunol
, vol.9
, pp. 194-202
-
-
Tone, Y.1
Furuuchi, K.2
Kojima, Y.3
Tykocinski, M.L.4
Greene, M.I.5
Tone, M.6
-
80
-
-
65549100376
-
Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1
-
Josefowicz S.Z., Wilson C.B., Rudensky A.Y. Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. J Immunol 2009, 182:6648-6652.
-
(2009)
J Immunol
, vol.182
, pp. 6648-6652
-
-
Josefowicz, S.Z.1
Wilson, C.B.2
Rudensky, A.Y.3
-
81
-
-
34547188748
-
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
-
Zhou L., Ivanov I.I., Spolski R., Min R., Shenderov K., Egawa T., et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007, 8:967-974.
-
(2007)
Nat Immunol
, vol.8
, pp. 967-974
-
-
Zhou, L.1
Ivanov, I.I.2
Spolski, R.3
Min, R.4
Shenderov, K.5
Egawa, T.6
-
82
-
-
46749138596
-
Molecular antagonism and plasticity of regulatory and inflammatory T cell programs
-
Yang X.O., Nurieva R., Martinez G.J., Kang H.S., Chung Y., Pappu B.P., et al. Molecular antagonism and plasticity of regulatory and inflammatory T cell programs. Immunity 2008, 29:44-56.
-
(2008)
Immunity
, vol.29
, pp. 44-56
-
-
Yang, X.O.1
Nurieva, R.2
Martinez, G.J.3
Kang, H.S.4
Chung, Y.5
Pappu, B.P.6
-
83
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence A., Tato C.M., Davidson T.S., Kanno Y., Chen Z., Yao Z., et al. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007, 26:371-381.
-
(2007)
Immunity
, vol.26
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
Kanno, Y.4
Chen, Z.5
Yao, Z.6
-
84
-
-
5644300399
-
Retinoic acid imprints gut-homing specificity on T cells
-
Iwata M., Hirakiyama A., Eshima Y., Kagechika H., Kato C., Song S.Y. Retinoic acid imprints gut-homing specificity on T cells. Immunity 2004, 21:527-538.
-
(2004)
Immunity
, vol.21
, pp. 527-538
-
-
Iwata, M.1
Hirakiyama, A.2
Eshima, Y.3
Kagechika, H.4
Kato, C.5
Song, S.Y.6
-
85
-
-
79960453738
-
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity
-
Haribhai D., Williams J.B., Jia S., Nickerson D., Schmitt E.G., Edwards B., et al. A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity 2011, 35:109-122.
-
(2011)
Immunity
, vol.35
, pp. 109-122
-
-
Haribhai, D.1
Williams, J.B.2
Jia, S.3
Nickerson, D.4
Schmitt, E.G.5
Edwards, B.6
-
86
-
-
33846980131
-
Epigenetic control of the foxp3 locus in regulatory T cells
-
Floess S., Freyer J., Siewert C., Baron U., Olek S., Polansky J., et al. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 2007, 5:e38.
-
(2007)
PLoS Biol
, vol.5
-
-
Floess, S.1
Freyer, J.2
Siewert, C.3
Baron, U.4
Olek, S.5
Polansky, J.6
-
87
-
-
77951638740
-
Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
-
Thornton A.M., Korty P.E., Tran D.Q., Wohlfert E.A., Murray P.E., Belkaid Y., et al. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol 2010, 184:3433-3441.
-
(2010)
J Immunol
, vol.184
, pp. 3433-3441
-
-
Thornton, A.M.1
Korty, P.E.2
Tran, D.Q.3
Wohlfert, E.A.4
Murray, P.E.5
Belkaid, Y.6
-
88
-
-
79956315886
-
Intestinal bacterial colonization induces mutualistic regulatory T cell responses
-
Geuking M.B., Cahenzli J., Lawson M.A., Ng D.C., Slack E., Hapfelmeier S., et al. Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity 2011, 34:794-806.
-
(2011)
Immunity
, vol.34
, pp. 794-806
-
-
Geuking, M.B.1
Cahenzli, J.2
Lawson, M.A.3
Ng, D.C.4
Slack, E.5
Hapfelmeier, S.6
-
89
-
-
80054020840
-
Peripheral education of the immune system by colonic commensal microbiota
-
Lathrop S.K., Bloom S.M., Rao S.M., Nutsch K., Lio C.-W., Santacruz N., et al. Peripheral education of the immune system by colonic commensal microbiota. Nature 2011, 478:250-254.
-
(2011)
Nature
, vol.478
, pp. 250-254
-
-
Lathrop, S.K.1
Bloom, S.M.2
Rao, S.M.3
Nutsch, K.4
Lio, C.-W.5
Santacruz, N.6
-
90
-
-
34547769253
-
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
-
Benson M.J., Pino-Lagos K., Rosemblatt M., Noelle R.J. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med 2007, 204:1765-1774.
-
(2007)
J Exp Med
, vol.204
, pp. 1765-1774
-
-
Benson, M.J.1
Pino-Lagos, K.2
Rosemblatt, M.3
Noelle, R.J.4
-
91
-
-
34548764423
-
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
-
Denning T.L., Wang Y.C., Patel S.R., Williams I.R., Pulendran B. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat Immunol 2007, 8:1086-1094.
-
(2007)
Nat Immunol
, vol.8
, pp. 1086-1094
-
-
Denning, T.L.1
Wang, Y.C.2
Patel, S.R.3
Williams, I.R.4
Pulendran, B.5
-
92
-
-
77955634800
-
Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine
-
Manicassamy S., Reizis B., Ravindran R., Nakaya H., Salazar-Gonzalez R.M., Wang Y.C., et al. Activation of beta-catenin in dendritic cells regulates immunity versus tolerance in the intestine. Science 2010, 329:849-853.
-
(2010)
Science
, vol.329
, pp. 849-853
-
-
Manicassamy, S.1
Reizis, B.2
Ravindran, R.3
Nakaya, H.4
Salazar-Gonzalez, R.M.5
Wang, Y.C.6
-
93
-
-
53349173070
-
Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine
-
Ivanov I.I., Frutos Rde L., Manel N., Yoshinaga K., Rifkin D.B., Sartor R.B., et al. Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 2008, 4:337-349.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 337-349
-
-
Ivanov, I.I.1
Frutos Rde, L.2
Manel, N.3
Yoshinaga, K.4
Rifkin, D.B.5
Sartor, R.B.6
-
94
-
-
34447580869
-
Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis
-
Min B., Thornton A., Caucheteux S.M., Younes S.A., Oh K., Hu-Li J., et al. Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis. Eur J Immunol 2007, 37:1916-1923.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1916-1923
-
-
Min, B.1
Thornton, A.2
Caucheteux, S.M.3
Younes, S.A.4
Oh, K.5
Hu-Li, J.6
-
95
-
-
44949127290
-
Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells
-
Ishikawa H., Tanaka K., Maeda Y., Aiba Y., Hata A., Tsuji N.M., et al. Effect of intestinal microbiota on the induction of regulatory CD25+ CD4+ T cells. Clin Exp Immunol 2008, 153:127-135.
-
(2008)
Clin Exp Immunol
, vol.153
, pp. 127-135
-
-
Ishikawa, H.1
Tanaka, K.2
Maeda, Y.3
Aiba, Y.4
Hata, A.5
Tsuji, N.M.6
-
96
-
-
33748855345
-
Impaired regulatory T cell function in germ-free mice
-
Ostman S., Rask C., Wold A.E., Hultkrantz S., Telemo E. Impaired regulatory T cell function in germ-free mice. Eur J Immunol 2006, 36:2336-2346.
-
(2006)
Eur J Immunol
, vol.36
, pp. 2336-2346
-
-
Ostman, S.1
Rask, C.2
Wold, A.E.3
Hultkrantz, S.4
Telemo, E.5
-
97
-
-
27444440273
-
Influence of intestinal bacteria on induction of regulatory T cells: lessons from a transfer model of colitis
-
Strauch U.G., Obermeier F., Grunwald N., Gurster S., Dunger N., Schultz M., et al. Influence of intestinal bacteria on induction of regulatory T cells: lessons from a transfer model of colitis. Gut 2005, 54:1546-1552.
-
(2005)
Gut
, vol.54
, pp. 1546-1552
-
-
Strauch, U.G.1
Obermeier, F.2
Grunwald, N.3
Gurster, S.4
Dunger, N.5
Schultz, M.6
-
98
-
-
78149310029
-
A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota
-
Chinen T., Volchkov P.Y., Chervonsky A.V., Rudensky A.Y. A critical role for regulatory T cell-mediated control of inflammation in the absence of commensal microbiota. J Exp Med 2010, 207:2323-2330.
-
(2010)
J Exp Med
, vol.207
, pp. 2323-2330
-
-
Chinen, T.1
Volchkov, P.Y.2
Chervonsky, A.V.3
Rudensky, A.Y.4
-
99
-
-
14844349149
-
Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells
-
Di Giacinto C., Marinaro M., Sanchez M., Strober W., Boirivant M. Probiotics ameliorate recurrent Th1-mediated murine colitis by inducing IL-10 and IL-10-dependent TGF-beta-bearing regulatory cells. J Immunol 2005, 174:3237-3246.
-
(2005)
J Immunol
, vol.174
, pp. 3237-3246
-
-
Di Giacinto, C.1
Marinaro, M.2
Sanchez, M.3
Strober, W.4
Boirivant, M.5
-
100
-
-
61449199478
-
Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice
-
Karimi K., Inman M.D., Bienenstock J., Forsythe P. Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice. Am J Respir Crit Care Med 2009, 179:186-193.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 186-193
-
-
Karimi, K.1
Inman, M.D.2
Bienenstock, J.3
Forsythe, P.4
-
101
-
-
74249088146
-
Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response
-
Livingston M., Loach D., Wilson M., Tannock G.W., Baird M. Gut commensal Lactobacillus reuteri 100-23 stimulates an immunoregulatory response. Immunol Cell Biol 2009, 88:99-102.
-
(2009)
Immunol Cell Biol
, vol.88
, pp. 99-102
-
-
Livingston, M.1
Loach, D.2
Wilson, M.3
Tannock, G.W.4
Baird, M.5
-
102
-
-
34548842184
-
Lactobacillus Acidophilus strain L-92 regulates the production of Th1 cytokine as well as Th2 cytokines
-
Torii A., Torii S., Fujiwara S., Tanaka H., Inagaki N., Nagai H. Lactobacillus Acidophilus strain L-92 regulates the production of Th1 cytokine as well as Th2 cytokines. Allergol Int 2007, 56:293-301.
-
(2007)
Allergol Int
, vol.56
, pp. 293-301
-
-
Torii, A.1
Torii, S.2
Fujiwara, S.3
Tanaka, H.4
Inagaki, N.5
Nagai, H.6
-
103
-
-
34347271190
-
A key role of dendritic cells in probiotic functionality
-
Foligne B., Zoumpopoulou G., Dewulf J., Ben Younes A., Chareyre F., Sirard J.C., et al. A key role of dendritic cells in probiotic functionality. PLoS One 2007, 2:e313.
-
(2007)
PLoS One
, vol.2
-
-
Foligne, B.1
Zoumpopoulou, G.2
Dewulf, J.3
Ben Younes, A.4
Chareyre, F.5
Sirard, J.C.6
-
104
-
-
33947308933
-
Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice
-
Forsythe P., Inman M.D., Bienenstock J. Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. Am J Respir Crit Care Med 2007, 175:561-569.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 561-569
-
-
Forsythe, P.1
Inman, M.D.2
Bienenstock, J.3
-
105
-
-
50849119097
-
Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation
-
O'Mahony C., Scully P., O'Mahony D., Murphy S., O'Brien F., Lyons A., et al. Commensal-induced regulatory T cells mediate protection against pathogen-stimulated NF-kappaB activation. PLoS Pathog 2008, 4:e1000112.
-
(2008)
PLoS Pathog
, vol.4
-
-
O'Mahony, C.1
Scully, P.2
O'Mahony, D.3
Murphy, S.4
O'Brien, F.5
Lyons, A.6
-
106
-
-
0030297089
-
The indigenous gastrointestinal microflora
-
Berg R.D. The indigenous gastrointestinal microflora. Trends Microbiol 1996, 4:430-435.
-
(1996)
Trends Microbiol
, vol.4
, pp. 430-435
-
-
Berg, R.D.1
-
107
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal inflammatory disease
-
Mazmanian S.K., Round J.L., Kasper D.L. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 2008, 453:620-625.
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
108
-
-
22144490199
-
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
-
Mazmanian S.K., Liu C.H., Tzianabos A.O., Kasper D.L. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 2005, 122:107-118.
-
(2005)
Cell
, vol.122
, pp. 107-118
-
-
Mazmanian, S.K.1
Liu, C.H.2
Tzianabos, A.O.3
Kasper, D.L.4
-
109
-
-
0021923837
-
Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice
-
Itoh K., Mitsuoka T. Characterization of clostridia isolated from faeces of limited flora mice and their effect on caecal size when associated with germ-free mice. Lab Anim 1985, 19:111-118.
-
(1985)
Lab Anim
, vol.19
, pp. 111-118
-
-
Itoh, K.1
Mitsuoka, T.2
-
110
-
-
0035815750
-
Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta
-
D'Angelo M., Billings P.C., Pacifici M., Leboy P.S., Kirsch T. Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta. J Biol Chem 2001, 276:11347-11353.
-
(2001)
J Biol Chem
, vol.276
, pp. 11347-11353
-
-
D'Angelo, M.1
Billings, P.C.2
Pacifici, M.3
Leboy, P.S.4
Kirsch, T.5
-
111
-
-
70349488325
-
Low counts of Faecalibacterium prausnitzii in colitis microbiota
-
Sokol H., Seksik P., Furet J.P., Firmesse O., Nion-Larmurier I., Beaugerie L., et al. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis 2009, 15:1183-1189.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 1183-1189
-
-
Sokol, H.1
Seksik, P.2
Furet, J.P.3
Firmesse, O.4
Nion-Larmurier, I.5
Beaugerie, L.6
-
112
-
-
55949124035
-
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
-
Sokol H., Pigneur B., Watterlot L., Lakhdari O., Bermudez-Humaran L.G., Gratadoux J.J., et al. Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 2008, 105:16731-16736.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 16731-16736
-
-
Sokol, H.1
Pigneur, B.2
Watterlot, L.3
Lakhdari, O.4
Bermudez-Humaran, L.G.5
Gratadoux, J.J.6
-
113
-
-
35348857386
-
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
-
Frank D.N., St Amand A.L., Feldman R.A., Boedeker E.C., Harpaz N., Pace N.R. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A 2007, 104:13780-13785.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13780-13785
-
-
Frank, D.N.1
St Amand, A.L.2
Feldman, R.A.3
Boedeker, E.C.4
Harpaz, N.5
Pace, N.R.6
-
114
-
-
79956078164
-
Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
-
Bloom S.M., Bijanki V.N., Nava G.M., Sun L., Malvin N.P., Donermeyer D.L., et al. Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe 2011, 9:390-403.
-
(2011)
Cell Host Microbe
, vol.9
, pp. 390-403
-
-
Bloom, S.M.1
Bijanki, V.N.2
Nava, G.M.3
Sun, L.4
Malvin, N.P.5
Donermeyer, D.L.6
-
115
-
-
79952389800
-
Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens
-
DePaolo R.W., Abadie V., Tang F., Fehlner-Peach H., Hall J.A., Wang W., et al. Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature 2011, 471:220-224.
-
(2011)
Nature
, vol.471
, pp. 220-224
-
-
DePaolo, R.W.1
Abadie, V.2
Tang, F.3
Fehlner-Peach, H.4
Hall, J.A.5
Wang, W.6
-
116
-
-
72949102295
-
Tissue-mediated control of immunopathology in coeliac disease
-
Jabri B., Sollid L.M. Tissue-mediated control of immunopathology in coeliac disease. Nat Rev Immunol 2009, 9:858-870.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 858-870
-
-
Jabri, B.1
Sollid, L.M.2
-
117
-
-
0042324649
-
Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease
-
Mention J.J., Ben Ahmed M., Begue B., Barbe U., Verkarre V., Asnafi V., et al. Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology 2003, 125:730-745.
-
(2003)
Gastroenterology
, vol.125
, pp. 730-745
-
-
Mention, J.J.1
Ben Ahmed, M.2
Begue, B.3
Barbe, U.4
Verkarre, V.5
Asnafi, V.6
-
118
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., et al. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
-
119
-
-
77950251400
-
A human gut microbial gene catalogue established by metagenomic sequencing
-
Qin J., Li R., Raes J., Arumugam M., Burgdorf K.S., Manichanh C., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010, 464:59-65.
-
(2010)
Nature
, vol.464
, pp. 59-65
-
-
Qin, J.1
Li, R.2
Raes, J.3
Arumugam, M.4
Burgdorf, K.S.5
Manichanh, C.6
|