Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12-and gamma interferon- dependent mechanism

Infection and Immunity

Volumn 66, Issue 11, 1998, Pages 5157-5166

  Kullberg, Marika C ^a   Ward, Jerrold M ^b   Gorelick, Peter L ^c   Caspar, Patricia ^a   Hieny, Sara ^a   Cheever, Allen ^a,d   Jankovic, Dragana ^a   Sher, Alan ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c SAIC FREDERICK INC   (United States)

^d BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G2B; IMMUNOGLOBULIN G3; INTERLEUKIN 10; INTERLEUKIN 12;

ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNODEFICIENCY; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HELICOBACTER HEPATICUS; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0032425062     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.11.5157-5166.1998     Document Type: Article

References (3)

1. Battles, J. K., J. C. Williamson, K. M. Pike, P. L. Gorelick, J. M. Ward, and M. A. Gonda. 1995. Diagnostic assay for Helicobacter hepaticus based on nucleotide sequence of its 16S rRNA gene. J. Clin. Microbiol. 33:1344-1347.
2. + TH1-like responses. J. Clin. Investig. 98:1010-1020.
3. Cahill, R. J., C. J. Foltz, J. G. Fox, C. A. Dangler, F. Powrie, and D. B. Schauer. 1997. Inflammatory bowel disease: an immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus. Infect. Immun. 65:3126-3131.