Has the microbiota played a critical role in the evolution of the adaptive immune system?

Science

Volumn 330, Issue 6012, 2010, Pages 1768-1773

  Lee, Yun Kyung ^a   Mazmanian, Sarkis K ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR FOXP3;

ADULT; BACTERIUM; COEVOLUTION; FITNESS; HOST-PATHOGEN INTERACTION; IMMUNE SYSTEM; MICROBIAL ECOLOGY;

ADAPTIVE IMMUNITY; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BACTERIUM CULTURE; CD4+ T LYMPHOCYTE; CELL INTERACTION; COEVOLUTION; IMMUNE SYSTEM; IMMUNITY; IMMUNOMODULATION; IMMUNOPATHOLOGY; INTESTINE LYMPHATIC TISSUE; LEISHMANIA; LISTERIA MONOCYTOGENES; LYMPHOCYTE DIFFERENTIATION; MICROBIOME; MICROFLORA; MICROORGANISM; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; SYMBIOSIS;

ADAPTIVE IMMUNITY; ANIMALS; AUTOIMMUNE DISEASES; BACTERIA; BACTERIAL PHYSIOLOGICAL PHENOMENA; BIOLOGICAL EVOLUTION; CELL DIFFERENTIATION; HUMANS; IMMUNE TOLERANCE; IMMUNITY, INNATE; IMMUNITY, MUCOSAL; INTESTINAL MUCOSA; INTESTINES; METAGENOME; SYMBIOSIS; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY;

BACTERIA (MICROORGANISMS);

EID: 78650647326     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1195568     Document Type: Review

References (64)

1. P. J. Turnbaugh et al., Nature 449, 804 (2007).
2. J. Qin et al., Nature 464, 59 (2010).
3. P. G. Falk, L. V. Hooper, T. Midtvedt, J. I. Gordon, Microbiol. Mol. Biol. Rev. 62, 1157 (1998).
4. A. J. Macpherson, N. L. Harris, Nat. Rev. Immunol. 4, 478 (2004).
5. M. Pollard, N. Sharon, Infect. Immun. 2, 96 (1970).
6. H. Hoshi et al., Tohoku J. Exp. Med. 166, 297 (1992).
7. J. R. Glaister, Int. Arch. Allergy Appl. Immunol. 45, 719 (1973).
8. A. Lundin et al., Cell. Microbiol. 10, 1093 (2008).
9. S. Matsumoto, H. Setoyama, Y. Umesaki, Gastroenterology 103, 1777 (1992).
10. A. Imaoka et al., Eur. J. Immunol. 26, 945 (1996).
11. Y. Umesaki, H. Setoyama, S. Matsumoto, Y. Okada, Immunology 79, 32 (1993).
12. J. Duan, H. Chung, E. Troy, D. L. Kasper, Cell Host Microbe 7, 140 (2010).
13. J. H. Niess, F. Leithäuser, G. Adler, J. Reimann, J. Immunol. 180, 559 (2008).
14. D. Bouskra et al., Nature 456, 507 (2008).
15. M. C. Noverr, G. B. Huffnagle, Trends Microbiol. 12, 562 (2004).
16. S. K. Mazmanian, C. H. Liu, A. O. Tzianabos, D. L. Kasper, Cell 122, 107 (2005).
17. H. Bauer et al., Am. J. Pathol. 42, 471 (1963).
18. K. Smith, K. D. McCoy, A. J. Macpherson, Semin. Immunol. 19, 59 (2007).
19. T. B. Clarke et al., Nat. Med. 16, 228 (2010).
20. H. Inagaki, T. Suzuki, K. Nomoto, Y. Yoshikai, Infect. Immun. 64, 3280 (1996).
21. B. Stecher et al., PLoS Biol. 5, e244 (2007).
22. C. Lupp et al., Cell Host Microbe 2, 119 (2007).
23. E. Bettelli et al., Nature 441, 235 (2006).
24. J. D. Fontenot et al., Immunity 22, 329 (2005).
25. A. Foussat et al., J. Immunol. 171, 5018 (2003).
26. M. Battaglia, S. Gregori, R. Bacchetta, M. G. Roncarolo, Semin. Immunol. 18, 120 (2006).
27. S. Sakaguchi et al., Cell 133, 775 (2008).
28. Y. P. Rubtsov et al., Immunity 28, 546 (2008).
29. J. L. Coombes et al., J. Exp. Med. 204, 1757 (2007).
30. M. Boirivant, W. Strober, Curr. Opin. Gastroenterol. 23, 679 (2007).
31. J. L. Coombes, K. J. Maloy, Semin. Immunol. 19, 116 (2007).
32. C. O'Mahony et al., PLoS Pathog. 4, e1000112 (2008).
33. H. Sokol et al., Proc. Natl. Acad. Sci. U. S. A. 105, 16731 (2008).
34. S. K. Mazmanian, D. L. Kasper, Nat. Rev. Immunol. 6, 849 (2006).
35. S. K. Mazmanian, J. L. Round, D. L. Kasper, Nature 453, 620 (2008).
36. U. G. Strauch et al., Gut 54, 1546 (2005).
37. S. Östman, C. Rask, A. E. Wold, S. Hultkrantz, E. Telemo, Eur. J. Immunol. 36, 2336 (2006).
38. B. Min et al., Eur. J. Immunol. 37, 1916 (2007).
39. I. I. Ivanov et al., Cell Host Microbe 4, 337 (2008).
40. C. Zaph et al., J. Exp. Med. 205, 2191 (2008).
41. V. Gaboriau-Routhiau et al., Immunity 31, 677 (2009).
42. J. L. Round, S. K. Mazmanian, Proc. Natl. Acad. Sci. U. S. A. 107, 12204 (2010).
43. K. Atarashi et al., Science 10.1126/science.1198469 (2010).
44. R. Dobber, A. Hertogh-Huijbregts, J. Rozing, K. Bottomly, L. Nagelkerken, Dev. Immunol. 2, 141 (1992).
45. I. I. Ivanov et al., Cell 126, 1121 (2006).
46. K. Atarashi et al., Nature 455, 808 (2008).
47. I. I. Ivanov et al., Cell 139, 485 (2009).
48. J. Snel et al., Can. J. Microbiol. 44, 1177 (1998).
49. G. L. Talham, H. Q. Jiang, N. A. Bos, J. J. Cebra, Infect. Immun. 67, 1992 (1999).
50. Y. Umesaki, Y. Okada, S. Matsumoto, A. Imaoka, H. Setoyama, Microbiol. Immunol. 39, 555 (1995).
51. M. C. Noverr, G. B. Huffnagle, Clin. Exp. Allergy 35, 1511 (2005).
52. J. L. Round, S. K. Mazmanian, Nat. Rev. Immunol. 9, 313 (2009).
53. J. Ochoa-Repáraz et al., Mucosal Immunol. 3, 487 (2010).
54. H. J. Wu et al., Immunity 32, 815 (2010).
55. Y. K. Lee et al., Proc. Natl. Acad. Sci. U. S. A. 10.1073/pnas.1000082107 (2010).
56. J. Chow, S. K. Mazmanian, Cell Host Microbe 7, 265 (2010).
57. S. E. Baranzini et al., Nature 464, 1351 (2010).
58. L. V. Hooper, Nat. Rev. Microbiol. 7, 367 (2009).
59. L. Zhou et al., Nature 453, 236 (2008).
60. X. O. Yang et al., Immunity 29, 44 (2008).
61. C. T. Weaver, R. D. Hatton, P. R. Mangan, L. E. Harrington, Annu. Rev. Immunol. 25, 821 (2007).
62. M. McFall-Ngai, Nature 445, 153 (2007).
63. S. E. Baranzini, Curr. Opin. Immunol. 21, 596 (2009).
64. We thank members of the Mazmanian laboratory for their critical review of the manuscript. Supported by NIH grants DK078938, DK083633, and AI088626; the Damon Runyon Cancer Research Foundation; and the Crohn's and Colitis Foundation of America (S. K. M.).