메뉴 건너뛰기




Volumn 1, Issue 3, 2007, Pages 241-258

The molecular genetics of breast cancer and targeted therapy

Author keywords

Breast cancer; Oncogenes; Targeted therapy; Tumor suppressor genes

Indexed keywords


EID: 83255161994     PISSN: 11775475     EISSN: 11775491     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (29)

References (260)
  • 1
    • 12244260756 scopus 로고    scopus 로고
    • A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer
    • Adjei AA, Dy GK, Erlichman C, et al. 2003. A phase I trial of ISIS 2503, an antisense inhibitor of H-ras, in combination with gemcitabine in patients with advanced cancer. Clin Cancer Res, 9:115-23.
    • (2003) Clin Cancer Res , vol.9 , pp. 115-123
    • Adjei, A.A.1    Dy, G.K.2    Erlichman, C.3
  • 2
    • 1542751717 scopus 로고    scopus 로고
    • Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy
    • Akli S, Keyomarsi K. 2003. Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy. Cancer Biol Ther, 2(Suppl 1):S38-47.
    • (2003) Cancer Biol Ther , vol.2 , Issue.1 SUPPL.
    • Akli, S.1    Keyomarsi, K.2
  • 3
    • 4544343901 scopus 로고    scopus 로고
    • Low-molecular-weight cyclin E: The miss- ing link between biology and clinical outcome
    • Akli S, Keyomarsi K. 2004. Low-molecular-weight cyclin E: the miss- ing link between biology and clinical outcome. Breast Cancer Res, 6:188-91.
    • (2004) Breast Cancer Res , vol.6 , pp. 188-191
    • Akli, S.1    Keyomarsi, K.2
  • 4
    • 78751632869 scopus 로고    scopus 로고
    • In: Abeloff MD, Armitage JO, Niederhuber JE, et al eds. Clinical oncology. 3rd ed. Philadelphia, PA: Elsevier Churchill Livingstone
    • Alessandro R, Clair T, Liotta LA, et al. 2004. The cellular microenviron- ment. In: Abeloff MD, Armitage JO, Niederhuber JE, et al eds. Clinical oncology. 3rd ed. Philadelphia, PA: Elsevier Churchill Livingstone. p 47-58.
    • (2004) The Cellular Microenviron- Ment , pp. 47-58
    • Alessandro, R.1    Clair, T.2    Liotta, L.A.3
  • 5
    • 0037388204 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic breast cancer cells
    • Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. 2003. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA, 100:3983-8.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3983-3988
    • Al-Hajj, M.1    Wicha, M.S.2    Benito-Hernandez, A.3
  • 6
    • 33745673353 scopus 로고    scopus 로고
    • Aromatase inhibitors in breast cancer
    • Altundag K, Ibrahim NK. 2006. Aromatase inhibitors in breast cancer. Oncologist, 11:553-62.
    • (2006) Oncologist , vol.11 , pp. 553-562
    • Altundag, K.1    Ibrahim, N.K.2
  • 7
    • 33749002551 scopus 로고    scopus 로고
    • Models of genetic susceptibility to cancer
    • Antoniou AC, Easton DF. 2006. Models of genetic susceptibility to cancer. Oncogene, 25:5898-905.
    • (2006) Oncogene , vol.25 , pp. 5898-5905
    • Antoniou, A.C.1    Easton, D.F.2
  • 8
    • 23044508946 scopus 로고    scopus 로고
    • Cyclin D1 in breast cancer pathogenesis
    • Arnold A, Papanikolaou A. 2005. Cyclin D1 in breast cancer pathogenesis. J Clin Oncol, 23:4215-24.
    • (2005) J Clin Oncol , vol.23 , pp. 4215-4224
    • Arnold, A.1    Papanikolaou, A.2
  • 9
    • 33846004477 scopus 로고    scopus 로고
    • PTEN enters the nuclear age
    • Baker SJ. 2007. PTEN enters the nuclear age. Cell, 128:25-8.
    • (2007) Cell , vol.128 , pp. 25-28
    • Baker, S.J.1
  • 10
    • 0035037366 scopus 로고    scopus 로고
    • Molecular targets for breast cancer therapy and prevention
    • Bange J, Zwick E, Ullrich A. 2001. Molecular targets for breast cancer therapy and prevention. Nat Med, 7:548-52.
    • (2001) Nat Med , vol.7 , pp. 548-552
    • Bange, J.1    Zwick, E.2    Ullrich, A.3
  • 11
    • 33846064604 scopus 로고    scopus 로고
    • Adjuvant trastuzumab: A milestone in the treatment of HER-2-positive early breast cancer
    • Baselga J, Perez EA, Pienkowski T, et al. 2006. Adjuvant trastuzumab: a milestone in the treatment of HER-2-positive early breast cancer. Oncologist, 11(Suppl 1):4-12.
    • (2006) Oncologist , vol.11 , Issue.1 SUPPL. , pp. 4-12
    • Baselga, J.1    Perez, E.A.2    Pienkowski, T.3
  • 12
    • 24744465206 scopus 로고    scopus 로고
    • The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity
    • Basso AD, Mirza A, Liu G, et al. 2005. The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity. J Biol Chem, 280:31101-8.
    • (2005) J Biol Chem , vol.280 , pp. 31101-31108
    • Basso, A.D.1    Mirza, A.2    Liu, G.3
  • 13
  • 14
    • 0037151382 scopus 로고    scopus 로고
    • On the use of familial aggregation in population-based case probands for calculating penetrance
    • Begg CB. 2002. On the use of familial aggregation in population-based case probands for calculating penetrance. J Natl Cancer Inst, 94:1221-6.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1221-1226
    • Begg, C.B.1
  • 15
    • 33645310632 scopus 로고    scopus 로고
    • Cyclin E overexpression reduces infiltrative growth in breast cancer: Yet another link between proliferation control and tumor invasion
    • Berglund P, Landberg G. 2006. Cyclin E overexpression reduces infiltrative growth in breast cancer: yet another link between proliferation control and tumor invasion. Cell Cycle, 5:606-9.
    • (2006) Cell Cycle , vol.5 , pp. 606-609
    • Berglund, P.1    Landberg, G.2
  • 16
    • 0029057890 scopus 로고
    • Oncogene amplifica- tion and prognosis in breast cancer; relationship and systemic treatment
    • Berns EMJJ, Foekens JA, van Staveren IL, et al. 1995. Oncogene amplifica- tion and prognosis in breast cancer; relationship and systemic treatment. Gene, 159:11-8.
    • (1995) Gene , vol.159 , pp. 11-18
    • Berns, E.M.J.J.1    Foekens, J.A.2    van Staveren, I.L.3
  • 17
    • 14644439903 scopus 로고    scopus 로고
    • Chemosensitization by antisense oligonucleotides targeting MDM2
    • Bianco R, Ciardiello F, Tortora G. 2005. Chemosensitization by antisense oligonucleotides targeting MDM2. Curr Cancer Drug Targets, 5:51-6.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 51-56
    • Bianco, R.1    Ciardiello, F.2    Tortora, G.3
  • 18
    • 0033646933 scopus 로고    scopus 로고
    • Loss of heterozygosity at 13q14 correlates with RB1 gene underexpression in human breast cancer
    • Bièche I, Lidereau R. 2000. Loss of heterozygosity at 13q14 correlates with RB1 gene underexpression in human breast cancer. Mol Carcinog, 29:151-8.
    • (2000) Mol Carcinog , vol.29 , pp. 151-158
    • Bièche, I.1    Lidereau, R.2
  • 19
    • 0037221767 scopus 로고    scopus 로고
    • TP53 and breast cancer
    • Børresen-Dale AL. 2003. TP53 and breast cancer. Hum Mutat, 21:292-300.
    • (2003) Hum Mutat , vol.21 , pp. 292-300
    • Børresen-Dale, A.L.1
  • 20
    • 33845972969 scopus 로고    scopus 로고
    • The retinoblastoma tumor suppres- sor modifies the therapeutic response of breast cancer
    • Bosco EE, Wang Y, Xu H, et al. 2007. The retinoblastoma tumor suppres- sor modifies the therapeutic response of breast cancer. J Clin Invest, 117:218-28.
    • (2007) J Clin Invest , vol.117 , pp. 218-228
    • Bosco, E.E.1    Wang, Y.2    Xu, H.3
  • 21
    • 30944442856 scopus 로고    scopus 로고
    • The Akt pathway in human breast cancer: A tissue-array-based analysis
    • Bose S, Chandran S, Mirocha JM, et al. 2006. The Akt pathway in human breast cancer: a tissue-array-based analysis. Mod Pathol, 19:238-45.
    • (2006) Mod Pathol , vol.19 , pp. 238-245
    • Bose, S.1    Chandran, S.2    Mirocha, J.M.3
  • 22
    • 33847366186 scopus 로고    scopus 로고
    • Restoration of wild-type p53 function in human cancer: Relevance for tumor therapy
    • Bossi G, Sacchi A. 2007. Restoration of wild-type p53 function in human cancer: relevance for tumor therapy. Head Neck, 29:272-84.
    • (2007) Head Neck , vol.29 , pp. 272-284
    • Bossi, G.1    Sacchi, A.2
  • 27
    • 34250210772 scopus 로고    scopus 로고
    • Environmental pollutants, diet, physical activity, body size, and breast cancer: Where do we stand in research to identify opportunities for prevention?
    • Brody JG, Rudel RA, Michels KB, et al. 2007. Environmental pollutants, diet, physical activity, body size, and breast cancer: where do we stand in research to identify opportunities for prevention? Cancer, 109:2627-34.
    • (2007) Cancer , vol.109 , pp. 2627-2634
    • Brody, J.G.1    Rudel, R.A.2    Michels, K.B.3
  • 28
    • 17244375049 scopus 로고    scopus 로고
    • Specific killing of BRCA2- deficient tumours with inhibitors of poly(ADP-ribose) polymerase
    • Bryant HE, Schultz N, Thomas HD, et al. 2005. Specific killing of BRCA2- deficient tumours with inhibitors of poly(ADP-ribose) polymerase. Nature, 434:913-17.
    • (2005) Nature , vol.434 , pp. 913-917
    • Bryant, H.E.1    Schultz, N.2    Thomas, H.D.3
  • 29
    • 2942592008 scopus 로고    scopus 로고
    • Dual kinase inhibition in the treatment of breast cancer: Initial experience with the EGFR/ErbB-2 inhibitor lapatinib
    • Burris HA III. 2004. Dual kinase inhibition in the treatment of breast cancer: initial experience with the EGFR/ErbB-2 inhibitor lapatinib. Oncologist, 9(Suppl 3):10-5.
    • (2004) Oncologist , vol.9 , Issue.3 SUPPL. , pp. 10-15
    • Burris III, H.A.1
  • 30
    • 25844515780 scopus 로고    scopus 로고
    • Downstream targets of growth factor and oestrogen signalling and endocrine resistance: The potential roles of c-Myc, cyclin D1 and cyclin
    • Butt AJ, McNeil CM, Musgrove EA, et al. 2005. Downstream targets of growth factor and oestrogen signalling and endocrine resistance: the potential roles of c-Myc, cyclin D1 and cyclin E. Endocr Relat Cancer, 12:S47-59.
    • (2005) E. Endocr Relat Cancer , vol.12
    • Butt, A.J.1    McNeil, C.M.2    Musgrove, E.A.3
  • 31
    • 19444387176 scopus 로고    scopus 로고
    • PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis
    • Bykov VJ, Zache N, Stridh H, et al. 2005. PRIMA-1(MET) synergizes with cisplatin to induce tumor cell apoptosis. Oncogene, 12:3484-91.
    • (2005) Oncogene , vol.12 , pp. 3484-3491
    • Bykov, V.J.1    Zache, N.2    Stridh, H.3
  • 33
    • 0036606633 scopus 로고    scopus 로고
    • Mechanism of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: Implications for the antiproliferative effects of estrogens
    • Carroll JS, Swarbrick A, Musgrove EA, et al. 2002. Mechanism of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of estrogens. Cancer Res, 62:3126-31.
    • (2002) Cancer Res , vol.62 , pp. 3126-3131
    • Carroll, J.S.1    Swarbrick, A.2    Musgrove, E.A.3
  • 34
    • 0013381910 scopus 로고    scopus 로고
    • First report: A phase II study of the safety and activity of CCI-779 for patients with locally advanced or metastatic breast cancer failing prior chemotherapy
    • Chan S, Johnson S, Scheulen M. 2002. First report: a phase II study of the safety and activity of CCI-779 for patients with locally advanced or metastatic breast cancer failing prior chemotherapy. Proc Am Soc Clin Oncol, 21:44a.
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • Chan, S.1    Johnson, S.2    Scheulen, M.3
  • 36
    • 0036648240 scopus 로고    scopus 로고
    • Truncating mutations of RB1CC1 in human breast cancer
    • Chano T, Kontani K, Teramoto K, et al. 2002. Truncating mutations of RB1CC1 in human breast cancer. Nat Genet, 31:285-8.
    • (2002) Nat Genet , vol.31 , pp. 285-288
    • Chano, T.1    Kontani, K.2    Teramoto, K.3
  • 37
    • 36448958512 scopus 로고    scopus 로고
    • Separation of anti-proliferation and anti-apoptotic functions of retinoblastoma protein through targeted mutations of its A/B domain
    • Chau BN, Pan CW, Wang JYJ. 2006. Separation of anti-proliferation and anti-apoptotic functions of retinoblastoma protein through targeted mutations of its A/B domain. PLoS ONE, 1:e82.
    • (2006) PLoS ONE , vol.1
    • Chau, B.N.1    Pan, C.W.2    Wang, J.Y.J.3
  • 38
    • 27744534653 scopus 로고    scopus 로고
    • Inhibition of P13K/Akt signaling: An emerging paradigm for targeted cancer therapy
    • Chen YL, Law PY, Loh HH. 2005. Inhibition of P13K/Akt signaling: an emerging paradigm for targeted cancer therapy. Curr Med Chem Anticancer Agents, 5:575-89.
    • (2005) Curr Med Chem Anticancer Agents , vol.5 , pp. 575-589
    • Chen, Y.L.1    Law, P.Y.2    Loh, H.H.3
  • 39
    • 33747121927 scopus 로고    scopus 로고
    • The future perspectives of breast cancer therapy
    • Chow LWC, Yiu CCP, Yip AYS, et al. 2006. The future perspectives of breast cancer therapy. Biomed Pharmacother, 60:259-62.
    • (2006) Biomed Pharmacother , vol.60 , pp. 259-262
    • Chow, L.W.C.1    Yiu, C.C.P.2    Yip, A.Y.S.3
  • 40
    • 33646241066 scopus 로고    scopus 로고
    • Targeting oncogenes to improve breast cancer chemotherapy
    • Christensen LA, Finch RA, Booker AJ, et al. 2006. Targeting oncogenes to improve breast cancer chemotherapy. Cancer Res, 66:4089-94.
    • (2006) Cancer Res , vol.66 , pp. 4089-4094
    • Christensen, L.A.1    Finch, R.A.2    Booker, A.J.3
  • 41
    • 33747876794 scopus 로고    scopus 로고
    • The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation
    • Chung JH, Ostrowski MC, Romigh T, et al. 2006. The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation. Hum Mol Genet, 15:2553-9.
    • (2006) Hum Mol Genet , vol.15 , pp. 2553-2559
    • Chung, J.H.1    Ostrowski, M.C.2    Romigh, T.3
  • 42
    • 0029002907 scopus 로고
    • Aberrant function of the Ras signal transduc- tion pathway in human breast cancer
    • Clark GJ, Der CJ. 1995. Aberrant function of the Ras signal transduc- tion pathway in human breast cancer. Breast Cancer Res Treat, 35:133-44.
    • (1995) Breast Cancer Res Treat , vol.35 , pp. 133-144
    • Clark, G.J.1    Der, C.J.2
  • 43
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells - perspective on current status and future directions: AARC workshop on cancer stem cells
    • Clarke MF, Dick JE, Dirks PB, et al. 2006. Cancer stem cells - perspective on current status and future directions: AARC workshop on cancer stem cells. Cancer Res, 66:9339-44.
    • (2006) Cancer Res , vol.66 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3
  • 44
    • 0036037189 scopus 로고    scopus 로고
    • The retinoblastoma family: Twins or distant cousins?
    • Claudio PP, Tonini T, Giordano A. 2002. The retinoblastoma family: twins or distant cousins? Genome Biol, 3:1-9.
    • (2002) Genome Biol , vol.3 , pp. 1-9
    • Claudio, P.P.1    Tonini, T.2    Giordano, A.3
  • 45
    • 21644456228 scopus 로고    scopus 로고
    • Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors
    • Collins I, Garrett MD. 2005. Targeting the cell division cycle in cancer: CDK and cell cycle checkpoint kinase inhibitors. Curr Opin Pharmacol, 5:366-73.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 366-373
    • Collins, I.1    Garrett, M.D.2
  • 46
    • 83255168334 scopus 로고    scopus 로고
    • Cancer: The matrix ix now in control
    • Comoglio PM, Trusolino L. 2005. Cancer: the matrix ix now in control. Nat Med, 11:1556-9.
    • (2005) Nat Med , vol.11 , pp. 1556-1559
    • Comoglio, P.M.1    Trusolino, L.2
  • 47
    • 33748643613 scopus 로고    scopus 로고
    • Emerging drugs to replace current leaders in first-line therapy for breast cancer
    • Cox MC, Dan TD, Swain SM. 2006. Emerging drugs to replace current leaders in first-line therapy for breast cancer. Expert Opin Emerging Drugs, 11:489-501.
    • (2006) Expert Opin Emerging Drugs , vol.11 , pp. 489-501
    • Cox, M.C.1    Dan, T.D.2    Swain, S.M.3
  • 48
    • 0035005244 scopus 로고    scopus 로고
    • Studies on oestrogen receptor-alpha and -beta mRNA during in breast cancer
    • Cullen R, Maguire TM, McDermott EW, et al. 2001. Studies on oestrogen receptor-alpha and -beta mRNA during in breast cancer. Eur J Cancer, 37:1118-22.
    • (2001) Eur J Cancer , vol.37 , pp. 1118-1122
    • Cullen, R.1    Maguire, T.M.2    McDermott, E.W.3
  • 49
    • 0037464769 scopus 로고    scopus 로고
    • Overview of the main outcomes in breast-cancer prevention
    • Cuzick J, Powles T, Veronesi U, et al. 2003. Overview of the main outcomes in breast-cancer prevention. Lancet, 361:296-300.
    • (2003) Lancet , vol.361 , pp. 296-300
    • Cuzick, J.1    Powles, T.2    Veronesi, U.3
  • 51
    • 0035126052 scopus 로고    scopus 로고
    • C-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations
    • D'Cruz CM, Gunther EJ, Boxer RB, et al. 2001. C-MYC induces mammary tumorigenesis by means of a preferred pathway involving spontaneous Kras2 mutations. Nat Med, 7:235-9.
    • (2001) Nat Med , vol.7 , pp. 235-239
    • D'cruz, C.M.1    Gunther, E.J.2    Boxer, R.B.3
  • 52
    • 33745712636 scopus 로고    scopus 로고
    • Cancer stem cells: Redefining the paradigm of cancer strate- gies
    • Dean M. 2006. Cancer stem cells: redefining the paradigm of cancer strate- gies. Mol Interv, 6:141-9.
    • (2006) Mol Interv , vol.6 , pp. 141-149
    • Dean, M.1
  • 53
    • 6944238452 scopus 로고    scopus 로고
    • Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway
    • deGraffenried LA, Fulcher L, Friedrichs WE, et al. 2004. Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. Ann Oncol, 15:1510-6.
    • (2004) Ann Oncol , vol.15 , pp. 1510-1516
    • Degraffenried, L.A.1    Fulcher, L.2    Friedrichs, W.E.3
  • 54
    • 33645003172 scopus 로고    scopus 로고
    • BRCA1: Cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
    • Deng CX. 2006. BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution. Nucleic Acids Res, 34:1416-26.
    • (2006) Nucleic Acids Res , vol.34 , pp. 1416-1426
    • Deng, C.X.1
  • 55
    • 0037386583 scopus 로고    scopus 로고
    • Breast cancer stem cells revealed
    • Dick JE. 2003. Breast cancer stem cells revealed. Proc Natl Acad Sci USA, 100:3547-9.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3547-3549
    • Dick, J.E.1
  • 56
    • 0034681264 scopus 로고    scopus 로고
    • The multiple roles of PTEN in tumor suppression
    • Cristofano AD, Pandolfi PP. 2000. The multiple roles of PTEN in tumor suppression. Cell, 100:387-90.
    • (2000) Cell , vol.100 , pp. 387-390
    • Cristofano, A.D.1    Pandolfi, P.P.2
  • 57
    • 33748067733 scopus 로고    scopus 로고
    • Retinoblastoma family genes
    • Du W, Pogoriler J. 2006. Retinoblastoma family genes. Oncogene, 25:5190-200.
    • (2006) Oncogene , vol.25 , pp. 5190-5200
    • Du, W.1    Pogoriler, J.2
  • 58
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson N. 1998. The regulation of E2F by pRB-family proteins. Genes Dev, 12:2245-62.
    • (1998) Genes Dev , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 59
    • 3042742432 scopus 로고    scopus 로고
    • Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis
    • Eckert LB, Repasky GA, Ülkü AS, et al. 2004. Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Res, 64:4585-92.
    • (2004) Cancer Res , vol.64 , pp. 4585-4592
    • Eckert, L.B.1    Repasky, G.A.2    Ülkü, A.S.3
  • 60
    • 27544492603 scopus 로고    scopus 로고
    • Origins of the mutational origin of cancer
    • Edler L, Kopp-Schneider A. 2005. Origins of the mutational origin of cancer. Int J Epidemiol, 34:1168-70.
    • (2005) Int J Epidemiol , vol.34 , pp. 1168-1170
    • Edler, L.1    Kopp-Schneider, A.2
  • 61
    • 46749158800 scopus 로고    scopus 로고
    • A randomized phase II study of two different schedules of RAD001C in patients with recurrent/metastatic breast cancer
    • (abst 3513)
    • Ellard S, Gelmon KA, Chia S, et al. 2007. A randomized phase II study of two different schedules of RAD001C in patients with recurrent/metastatic breast cancer. J Clin Oncol, 25 (abst 3513).
    • (2007) J Clin Oncol , vol.25
    • Ellard, S.1    Gelmon, K.A.2    Chia, S.3
  • 62
    • 14544270987 scopus 로고    scopus 로고
    • Screening for breast cancer
    • Elmore JG, Armstrong K, Lehman CD, et al. 2007. Screening for breast cancer. JAMA, 293:1245-56.
    • (2007) JAMA , vol.293 , pp. 1245-1256
    • Elmore, J.G.1    Armstrong, K.2    Lehman, C.D.3
  • 63
    • 0037312899 scopus 로고    scopus 로고
    • The not-so innocent bystander: The microenvironment as a therapeutic target in cancer
    • Erickson AC, Barcellos-Hoff MH. 2003. The not-so innocent bystander: the microenvironment as a therapeutic target in cancer. Expert Opin Ther Targets, 7:71-88.
    • (2003) Expert Opin Ther Targets , vol.7 , pp. 71-88
    • Erickson, A.C.1    Barcellos-Hoff, M.H.2
  • 64
    • 33644769085 scopus 로고    scopus 로고
    • High-throughput techniques in breast cancer: A clinical perspective
    • Espinosa E, Redondo A, Vara JÁF, et al. 2006. High-throughput techniques in breast cancer: a clinical perspective. Eur J Cancer, 42:598-607.
    • (2006) Eur J Cancer , vol.42 , pp. 598-607
    • Espinosa, E.1    Redondo, A.2    Vara, J.A.F.3
  • 65
    • 17244373777 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
    • Farmer H, McCabe N, Lord CJ, et al. 2005. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature, 434:917-21.
    • (2005) Nature , vol.434 , pp. 917-921
    • Farmer, H.1    McCabe, N.2    Lord, C.J.3
  • 66
    • 0025253945 scopus 로고
    • The role of ras and myc oncogenes in human solid tumours and their relevance in diagnosis and prognosis
    • Field JK, Spandidos DA. 1990. The role of ras and myc oncogenes in human solid tumours and their relevance in diagnosis and prognosis. Anticancer Res, 10:1-22.
    • (1990) Anticancer Res , vol.10 , pp. 1-22
    • Field, J.K.1    Spandidos, D.A.2
  • 67
  • 68
    • 0037972896 scopus 로고    scopus 로고
    • Response-specific and ligand dose-dependent modulation of estrogen receptor (ER)α activity by ERβ in the uterus
    • Frasor J, Danes JM, Komm B, et al. 2003. Response-specific and ligand dose-dependent modulation of estrogen receptor (ER)α activity by ERβ in the uterus. Endocrinology, 144:4562-74.
    • (2003) Endocrinology , vol.144 , pp. 4562-4574
    • Frasor, J.1    Danes, J.M.2    Komm, B.3
  • 69
    • 9444236895 scopus 로고    scopus 로고
    • Cyclin D1: Normal and abnormal functions
    • Fu M, Wang C, Li Z, et al. 2004. Cyclin D1: normal and abnormal functions. Endocrinology, 145:5439-47.
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3
  • 70
    • 0027690140 scopus 로고
    • Chromosome 11q13, c-erbB-2, and c-myc amplification in invasive breast carcinoma: Clinicopathologic correlations
    • Gaffey MJ, Frierson HFJ, Williams ME. 1993. Chromosome 11q13, c-erbB-2, and c-myc amplification in invasive breast carcinoma: clinicopathologic correlations. Mod Pathol, 6:654-9.
    • (1993) Mod Pathol , vol.6 , pp. 654-659
    • Gaffey, M.J.1    Frierson, H.F.J.2    Williams, M.E.3
  • 71
    • 33846205915 scopus 로고    scopus 로고
    • New agents in development of breast cancer
    • Gao X, Liu F. 2007. New agents in development of breast cancer. Curr Opin Obstet Gynecol, 19:68-74.
    • (2007) Curr Opin Obstet Gynecol , vol.19 , pp. 68-74
    • Gao, X.1    Liu, F.2
  • 72
    • 0032804162 scopus 로고    scopus 로고
    • Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype
    • Garcia JM, Silva JM, Dominguez G, et al. 1999. Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype. Breast Cancer Res Treat, 57:237-43.
    • (1999) Breast Cancer Res Treat , vol.57 , pp. 237-243
    • Garcia, J.M.1    Silva, J.M.2    Dominguez, G.3
  • 73
    • 18444404330 scopus 로고    scopus 로고
    • Targeted therapy: The fast pace of progress
    • Garrett C. 2005. Targeted therapy: the fast pace of progress. Cancer Control, 12:71-2.
    • (2005) Cancer Control , vol.12 , pp. 71-72
    • Garrett, C.1
  • 75
    • 30644470953 scopus 로고    scopus 로고
    • Therapy of breast cancer with molecular targeting agents
    • Gasparini G, Longo R, Torino F, et al. 2005. Therapy of breast cancer with molecular targeting agents. Ann Oncol, 16(Suppl 4):iv28-36.
    • (2005) Ann Oncol , vol.16 , Issue.4 SUPPL.
    • Gasparini, G.1    Longo, R.2    Torino, F.3
  • 76
    • 33845886440 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine for HER2-positive advanced breast cancer
    • Geyer CE, Foster J, Lindquist D, et al. 2006. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N Engl J Med, 355:2733-43.
    • (2006) N Engl J Med , vol.355 , pp. 2733-2743
    • Geyer, C.E.1    Foster, J.2    Lindquist, D.3
  • 77
    • 16844376315 scopus 로고    scopus 로고
    • Oncogenic Ras in tumor progression and metastasis
    • Giehl K. 2005. Oncogenic Ras in tumor progression and metastasis. Biol Chem, 386:193-205.
    • (2005) Biol Chem , vol.386 , pp. 193-205
    • Giehl, K.1
  • 78
    • 32944465388 scopus 로고    scopus 로고
    • Handikapping the race to develop inhibitors of the phosphoinoside 3-kinase/Akt/mammailian target of rapamycin pathway
    • Granville CA, Memmott RM, Gills JJ, et al. 2006. Handikapping the race to develop inhibitors of the phosphoinoside 3-kinase/Akt/mammailian target of rapamycin pathway. Clin Cancer Res, 12:679-89.
    • (2006) Clin Cancer Res , vol.12 , pp. 679-689
    • Granville, C.A.1    Memmott, R.M.2    Gills, J.J.3
  • 79
    • 33645524134 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase/Akt1/Par-4 axis: A cancer selective therapeutic agent
    • Goswami A, Ranganathan P, Rangnekar VM. 2006. The phosphoinositide 3-kinase/Akt1/Par-4 axis: a cancer selective therapeutic agent. Cancer Res, 66:2889-92.
    • (2006) Cancer Res , vol.66 , pp. 2889-2892
    • Goswami, A.1    Ranganathan, P.2    Rangnekar, V.M.3
  • 80
    • 33749023326 scopus 로고    scopus 로고
    • The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability
    • Gudmundsdottir K, Ashworth A. 2006. The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability. Oncogene, 25:5864-74.
    • (2006) Oncogene , vol.25 , pp. 5864-5874
    • Gudmundsdottir, K.1    Ashworth, A.2
  • 81
    • 23144467910 scopus 로고    scopus 로고
    • An expanding role for mTOR in cancer
    • Guerin DA, Sabatini DM. 2005. An expanding role for mTOR in cancer. TRENDS Mol Med, 11:353-61.
    • (2005) TRENDS Mol Med , vol.11 , pp. 353-361
    • Guerin, D.A.1    Sabatini, D.M.2
  • 82
    • 0024259860 scopus 로고
    • Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: Correlation with poor prognosis
    • Guerin M, Barrois M, Terrier MJ, et al. 1988. Overexpression of either c-myc or c-erbB-2/neu proto-oncogenes in human breast carcinomas: correlation with poor prognosis. Oncogene Res, 3:21-31.
    • (1988) Oncogene Res , vol.3 , pp. 21-31
    • Guerin, M.1    Barrois, M.2    Terrier, M.J.3
  • 83
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. 2000. The hallmarks of cancer. Cell, 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 84
    • 0037542854 scopus 로고    scopus 로고
    • Ras proteins: Different signals from different locations
    • Hancock JF. 2003. Ras proteins: different signals from different locations. Nat Rev Mol Cell Biol, 4:373-84.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 373-384
    • Hancock, J.F.1
  • 85
    • 24644520641 scopus 로고    scopus 로고
    • A long view of fashions in cancer research
    • Harris H. 2005. A long view of fashions in cancer research. Bioessays, 27:833-8.
    • (2005) Bioessays , vol.27 , pp. 833-838
    • Harris, H.1
  • 87
    • 1842477408 scopus 로고    scopus 로고
    • Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in Breast Cancer Cells
    • Harwell RM, Mull BB, Porter DC, et al. 2004. Activation of cyclin-dependent kinase 2 by full length and low molecular weight forms of cyclin E in breast cancer cells. J Biol Chem, 279:12695-705.
    • (2004) J Biol Chem , vol.279 , pp. 12695-12705
    • Harwell, R.M.1    Mull, B.B.2    Porter, D.C.3
  • 88
    • 13144293059 scopus 로고    scopus 로고
    • P53 Regulation: A family affair
    • Haupt Y. 2004. p53 regulation: a family affair. Cell Cycle, 3:884-5.
    • (2004) Cell Cycle , vol.3 , pp. 884-885
    • Haupt, Y.1
  • 89
    • 0038199515 scopus 로고    scopus 로고
    • The expression and function of estrogen receptor alpha and beta in human breast cancer and its clinical application
    • Hayashi SI, Eguchi H, Tanimoto K, et al. 2003. The expression and function of estrogen receptor alpha and beta in human breast cancer and its clinical application. Endocr Relat Cancer, 10:193-202.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 193-202
    • Hayashi, S.I.1    Eguchi, H.2    Tanimoto, K.3
  • 90
    • 7444232526 scopus 로고    scopus 로고
    • New targets for therapy in breast cancer: Farnesyltransferase inhibitors
    • Head J, Johnston SRD. 2004. New targets for therapy in breast cancer: farnesyltransferase inhibitors. Breast Cancer Res, 6:262-8.
    • (2004) Breast Cancer Res , vol.6 , pp. 262-268
    • Head, J.1    Johnston, S.R.D.2
  • 91
    • 0029686266 scopus 로고    scopus 로고
    • Proteins of the Myc network: Essential regulators of cell growth and differentiation
    • Henriksson M, Luscher B. 1996. Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv Cancer Res, 68:109-82.
    • (1996) Adv Cancer Res , vol.68 , pp. 109-182
    • Henriksson, M.1    Luscher, B.2
  • 92
    • 10644274482 scopus 로고    scopus 로고
    • Estrogen receptor mutations in human disease
    • Herynk MH, Fuqua SAW. 2004. Estrogen receptor mutations in human disease. Endocr Rev, 25:869-98.
    • (2004) Endocr Rev , vol.25 , pp. 869-898
    • Herynk, M.H.1    Fuqua, S.A.W.2
  • 93
    • 15544376261 scopus 로고    scopus 로고
    • Lessons in estrogen biology from knockout and transgenic animals
    • Hewitt SC, Harrell JC, Korach KS. 2005. Lessons in estrogen biology from knockout and transgenic animals. Annu Rev Physiol, 67:285-308.
    • (2005) Annu Rev Physiol , vol.67 , pp. 285-308
    • Hewitt, S.C.1    Harrell, J.C.2    Korach, K.S.3
  • 94
    • 33644559031 scopus 로고    scopus 로고
    • Identifying cancer stem cells in solid tumors: Case not proven
    • Hill RP. 2006. Identifying cancer stem cells in solid tumors: case not proven. Cancer Res, 66:1891-6.
    • (2006) Cancer Res , vol.66 , pp. 1891-1896
    • Hill, R.P.1
  • 95
    • 18444394024 scopus 로고    scopus 로고
    • Molecularly targeted therapies for breast cancer
    • Hobday TJ, Perez EA. 2005. Molecularly targeted therapies for breast cancer. Cancer Control, 12:73-81.
    • (2005) Cancer Control , vol.12 , pp. 73-81
    • Hobday, T.J.1    Perez, E.A.2
  • 96
    • 0037429725 scopus 로고    scopus 로고
    • The erbB receptors and their role in cancer progression
    • Holbro T, Civenni G, Hynes NE. 2003. The erbB receptors and their role in cancer progression. Exp Cell Res, 284:99-110.
    • (2003) Exp Cell Res , vol.284 , pp. 99-110
    • Holbro, T.1    Civenni, G.2    Hynes, N.E.3
  • 97
    • 33947230755 scopus 로고    scopus 로고
    • Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines
    • Hollestelle A, Elstrodt F, Nagel JHA, et al. 2007. Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines. Mol Cancer Res, 5:195-201.
    • (2007) Mol Cancer Res , vol.5 , pp. 195-201
    • Hollestelle, A.1    Elstrodt, F.2    Nagel, J.H.A.3
  • 99
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab - mechanism of action and use in clinical practice
    • Hudis CA. 2007. Trastuzumab - mechanism of action and use in clinical practice. N Engl J Med, 357:39-51.
    • (2007) N Engl J Med , vol.357 , pp. 39-51
    • Hudis, C.A.1
  • 100
    • 23044444181 scopus 로고    scopus 로고
    • Cyclin E as a prognostic and predictive marker in breast cancer
    • Hunt KK, Keyomarsi K. 2005. Cyclin E as a prognostic and predictive marker in breast cancer. Semin Cancer Biol, 15:319-26.
    • (2005) Semin Cancer Biol , vol.15 , pp. 319-326
    • Hunt, K.K.1    Keyomarsi, K.2
  • 101
    • 0032521537 scopus 로고    scopus 로고
    • BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichlo- roplatinum (II)
    • Husain HEG, Venkatraman ES, Spriggs DR. 1998. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichlo- roplatinum (II). Cancer Res, 58:1120-3.
    • (1998) Cancer Res , vol.58 , pp. 1120-1123
    • Husain, H.E.G.1    Venkatraman, E.S.2    Spriggs, D.R.3
  • 102
    • 15844388060 scopus 로고    scopus 로고
    • Estrogen receptors and their downstream targets in cancer
    • Ideka K, Inoue S. 2004. Estrogen receptors and their downstream targets in cancer. Arch Histol Cytol, 67:435-43.
    • (2004) Arch Histol Cytol , vol.67 , pp. 435-443
    • Ideka, K.1    Inoue, S.2
  • 103
    • 12344272908 scopus 로고    scopus 로고
    • Genetics of breast cancer
    • Ingvarsson S. 2004. Genetics of breast cancer. Drugs Today, 40:991-1002.
    • (2004) Drugs Today , vol.40 , pp. 991-1002
    • Ingvarsson, S.1
  • 107
    • 22144437391 scopus 로고    scopus 로고
    • Emerging targeted therapies for breast cancer
    • Johnson ML, Seidman AD. 2005. Emerging targeted therapies for breast cancer. Oncology, 19:611-8.
    • (2005) Oncology , vol.19 , pp. 611-618
    • Johnson, M.L.1    Seidman, A.D.2
  • 109
    • 0038352147 scopus 로고    scopus 로고
    • Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer
    • Johnston SRD, Hickish T, Ellis P, et al. 2003. Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer. J Clin Oncol, 21:2492-9.
    • (2003) J Clin Oncol , vol.21 , pp. 2492-2499
    • Johnston, S.R.D.1    Hickish, T.2    Ellis, P.3
  • 110
    • 33947714587 scopus 로고    scopus 로고
    • SERMs: Meeting the promise of multifunctional medicines
    • Jordan VC. 2007. SERMs: meeting the promise of multifunctional medicines. JNCI, 99:350-6.
    • (2007) JNCI , vol.99 , pp. 350-356
    • Jordan, V.C.1
  • 111
    • 33845929000 scopus 로고    scopus 로고
    • Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer
    • Jordan VC, Brodie AM. 2007. Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer. Steroids, 72:7-25.
    • (2007) Steroids , vol.72 , pp. 7-25
    • Jordan, V.C.1    Brodie, A.M.2
  • 112
    • 0037429737 scopus 로고    scopus 로고
    • Epidermal growth fac- tor receptor:Mechanisms of activation and signalling
    • Jorissen RN, Walker F, Pouliot N, et al. 2003. Epidermal growth fac- tor receptor:mechanisms of activation and signalling. Exp Cell Res, 284:31-53.
    • (2003) Exp Cell Res , vol.284 , pp. 31-53
    • Jorissen, R.N.1    Walker, F.2    Pouliot, N.3
  • 113
    • 2342658475 scopus 로고    scopus 로고
    • New targeted therapies in breast cancer
    • Kaklamani V, O'Regan RM. 2004. New targeted therapies in breast cancer. Semin Oncol, 31(Suppl 4):20-5.
    • (2004) Semin Oncol , vol.31 , Issue.4 SUPPL. , pp. 20-25
    • Kaklamani, V.1    O'Regan, R.M.2
  • 115
    • 34447500612 scopus 로고    scopus 로고
    • Risk-reducing salpingo-oophorectomy in patients with germline mutations in BRCA1 or BRCA 2
    • Kauff ND, Barakat RR. 2007. Risk-reducing salpingo-oophorectomy in patients with germline mutations in BRCA1 or BRCA 2. J Clin Oncol, 25:2921-7.
    • (2007) J Clin Oncol , vol.25 , pp. 2921-2927
    • Kauff, N.D.1    Barakat, R.R.2
  • 116
    • 34547100275 scopus 로고    scopus 로고
    • The resurgence of platinum-based cancer chemotherapy
    • Kelland L. 2007. The resurgence of platinum-based cancer chemotherapy. Nat Rev Cancer, 7:573-84.
    • (2007) Nat Rev Cancer , vol.7 , pp. 573-584
    • Kelland, L.1
  • 117
    • 4444339665 scopus 로고    scopus 로고
    • Oncogenic pathways in hereditary and sporadic breast cancer
    • Kenemans R, Verstraeten RA, Verheijen RHM. 2004. Oncogenic pathways in hereditary and sporadic breast cancer. Maturitas, 49:34-43.
    • (2004) Maturitas , vol.49 , pp. 34-43
    • Kenemans, R.1    Verstraeten, R.A.2    Verheijen, R.H.M.3
  • 118
    • 0029902170 scopus 로고    scopus 로고
    • Effect of age, breast density, and family history on the sensitivity of first screening mammography
    • Kerlikowske K, Grady D, Barclay J, et al. 1996. Effect of age, breast density, and family history on the sensitivity of first screening mammography. JAMA, 276:33-8.
    • (1996) JAMA , vol.276 , pp. 33-38
    • Kerlikowske, K.1    Grady, D.2    Barclay, J.3
  • 119
    • 6344246440 scopus 로고    scopus 로고
    • PTEN promoter is methylated in a proportion of invasive breast cancers
    • Khan S, Kumagai T, Vora J, et al. 2004. PTEN promoter is methylated in a proportion of invasive breast cancers. Int J Cancer, 112:407-10.
    • (2004) Int J Cancer , vol.112 , pp. 407-410
    • Khan, S.1    Kumagai, T.2    Vora, J.3
  • 120
    • 29444456417 scopus 로고    scopus 로고
    • Targeting the phosphatidylinositol-3-kinase/Akt pathway for the treatment of cancer
    • Kim D, Cheng GZ, Lindsley CW, et al. 2005. Targeting the phosphatidylinositol-3-kinase/Akt pathway for the treatment of cancer. Curr Opin Investig Drugs, 6:1250-8.
    • (2005) Curr Opin Investig Drugs , vol.6 , pp. 1250-1258
    • Kim, D.1    Cheng, G.Z.2    Lindsley, C.W.3
  • 121
    • 33644834046 scopus 로고    scopus 로고
    • Tumours and tremors: How PTEN regulation underlies both
    • Kim RH, Mak TW. 2006. Tumours and tremors: how PTEN regulation underlies both. Br J Cancer, 94:620-4.
    • (2006) Br J Cancer , vol.94 , pp. 620-624
    • Kim, R.H.1    Mak, T.W.2
  • 122
    • 0030932869 scopus 로고    scopus 로고
    • Gatekeepers and caretakers
    • Kinzler KW, Vogelstein B. 1997. Gatekeepers and caretakers. Nature, 386:761-2.
    • (1997) Nature , vol.386 , pp. 761-762
    • Kinzler, K.W.1    Vogelstein, B.2
  • 123
    • 0032524104 scopus 로고    scopus 로고
    • Landscaping the cancer terrain
    • Kinzler KW, Vogelstein B. 1998. Landscaping the cancer terrain. Science, 280:1036-7.
    • (1998) Science , vol.280 , pp. 1036-1037
    • Kinzler, K.W.1    Vogelstein, B.2
  • 124
    • 0033992633 scopus 로고    scopus 로고
    • Biochemical and clini- cal implications of the erbB/HER signaling network of growth factor receptors
    • Klapper LN, Kirschbaum MH, Sela M, et al. 2000. Biochemical and clini- cal implications of the erbB/HER signaling network of growth factor receptors. Adv Cancer Res, 77:25-79.
    • (2000) Adv Cancer Res , vol.77 , pp. 25-79
    • Klapper, L.N.1    Kirschbaum, M.H.2    Sela, M.3
  • 125
    • 33745906528 scopus 로고    scopus 로고
    • Retinoblastoma tumor suppressor: Where cancer meets the cell cycle
    • Knudsen ES, Knudsen KE. 2006. Retinoblastoma tumor suppressor: where cancer meets the cell cycle. Exp Biol Med, 231:1271-81.
    • (2006) Exp Biol Med , vol.231 , pp. 1271-1281
    • Knudsen, E.S.1    Knudsen, K.E.2
  • 126
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblasatoma
    • Knudson AG Jr. 1971. Mutation and cancer: statistical study of retinoblasatoma. Proc Natl Acad Sci USA, 68:820-3.
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 820-823
    • Knudson Jr., A.G.1
  • 127
    • 32944461545 scopus 로고    scopus 로고
    • Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-over-expression and trastuzumab-treated breast cancer cells
    • Konecny GE, Pegram MD, Venkatesan N, et al. 2006. Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-over-expression and trastuzumab-treated breast cancer cells. Cancer Res, 66:1630-9.
    • (2006) Cancer Res , vol.66 , pp. 1630-1639
    • Konecny, G.E.1    Pegram, M.D.2    Venkatesan, N.3
  • 128
    • 0030579801 scopus 로고    scopus 로고
    • Cloning of novel receptor expressed in rat prostrate and ovary
    • Kuiper GG, Enmark E, Pelto-Huikko M, et al. 1996. Cloning of novel receptor expressed in rat prostrate and ovary. Proc Natl Acad Sci USA, 93:5925-30.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5925-5930
    • Kuiper, G.G.1    Enmark, E.2    Pelto-Huikko, M.3
  • 129
    • 33745115304 scopus 로고    scopus 로고
    • Leclercq G. 2006. p53 and breast cancer: An update
    • Lacroix M, Toillon RA, Leclercq G. 2006. p53 and breast cancer: an update. Endocr Relat Cancer, 13:293-325.
    • Endocr Relat Cancer , vol.13 , pp. 293-325
    • Lacroix, M.1    Toillon, R.A.2
  • 130
    • 0027109075 scopus 로고
    • The guardian of the genome
    • Lane DP. 1992. p53: the guardian of the genome. Nature, 358:15-6.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 131
    • 19944434195 scopus 로고    scopus 로고
    • A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast cancer
    • Lebowitz PF, Eng-Wong J, Widemann BC, et al. 2005. A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast cancer. Clin Cancer Res, 11:1247-52.
    • (2005) Clin Cancer Res , vol.11 , pp. 1247-1252
    • Lebowitz, P.F.1    Eng-Wong, J.2    Widemann, B.C.3
  • 132
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phos- phatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, et al. 1997. PTEN, a putative protein tyrosine phos- phatase gene mutated in human brain, breast, and prostate cancer. Science, 275:1943-7.
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 133
    • 0033790685 scopus 로고    scopus 로고
    • Dickson RB. 2000. c-Myc in breast cancer
    • Liao DJ, Dickson RB. 2000. c-Myc in breast cancer. Endocr Relat Cancer, 7:143-64.
    • Endocr Relat Cancer , vol.7 , pp. 143-164
    • Liao, D.J.1
  • 134
    • 0031004088 scopus 로고    scopus 로고
    • Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
    • Liaw D, Marsh DJ, Li J, et al. 1997. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet, 16:64-7.
    • (1997) Nat Genet , vol.16 , pp. 64-67
    • Liaw, D.1    Marsh, D.J.2    Li, J.3
  • 135
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumor-host inter- face
    • Liotta LA, Kohn EC. 2001. The microenvironment of the tumor-host inter- face. Nature, 411:375-9.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 136
    • 8444233617 scopus 로고    scopus 로고
    • Silencing of hdm2 oncogene by siRNA inhibits p53-dependent human breast cancer
    • Liu TG, Yin JQ, Shang BY, et al. 2004. Silencing of hdm2 oncogene by siRNA inhibits p53-dependent human breast cancer. Cancer Gene Ther, 11:748-56.
    • (2004) Cancer Gene Ther , vol.11 , pp. 748-756
    • Liu, T.G.1    Yin, J.Q.2    Shang, B.Y.3
  • 137
    • 0037063165 scopus 로고    scopus 로고
    • The cyclin D1 high and cyclin E high subgroups of breast cancer: Separate pathways in tumorigenesis based on pattern of genetic aberrations and inactivation of the pRb node
    • Lodén M, Stoghall M, Nielsen NH, et al. 2002. The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorigenesis based on pattern of genetic aberrations and inactivation of the pRb node. Oncogene, 21:4680-90.
    • (2002) Oncogene , vol.21 , pp. 4680-4690
    • Lodén, M.1    Stoghall, M.2    Nielsen, N.H.3
  • 139
    • 0033604468 scopus 로고    scopus 로고
    • The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells
    • Lu Y, Lin YZ, LaPushin R, et al. 1999. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene, 18:7034-45.
    • (1999) Oncogene , vol.18 , pp. 7034-7045
    • Lu, Y.1    Lin, Y.Z.2    Lapushin, R.3
  • 140
    • 0345276609 scopus 로고    scopus 로고
    • Targeting the P13K-AKT pathway for cancer therapy
    • Lu Y, Wang H, Mills GB. 2003. Targeting the P13K-AKT pathway for cancer therapy. Rev Clin Exp Hematol, 7:205-28.
    • (2003) Rev Clin Exp Hematol , vol.7 , pp. 205-228
    • Lu, Y.1    Wang, H.2    Mills, G.B.3
  • 143
    • 0034002662 scopus 로고    scopus 로고
    • Tumor suppressor genes
    • Macleod K. 2000. Tumor suppressor genes. Curr Opin Genet Dev, 10:81-93.
    • (2000) Curr Opin Genet Dev , vol.10 , pp. 81-93
    • Macleod, K.1
  • 144
    • 0032904432 scopus 로고    scopus 로고
    • PTEN: A tumour suppressor that functions as a phospholipid phosphatase
    • Maehama T, Dixon JE. 1999. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol, 9:125-8.
    • (1999) Trends Cell Biol , vol.9 , pp. 125-128
    • Maehama, T.1    Dixon, J.E.2
  • 145
    • 34347226346 scopus 로고    scopus 로고
    • Protein kinase Cα determines HER2 fate in breast carcinoma cells with HER2 protein overexpression without gene amplification
    • Magnifico A, Albano L, Campaner S, et al. 2007. Protein kinase Cα determines HER2 fate in breast carcinoma cells with HER2 protein overexpression without gene amplification. Cancer Res, 67:5308-17.
    • (2007) Cancer Res , vol.67 , pp. 5308-5317
    • Magnifico, A.1    Albano, L.2    Campaner, S.3
  • 146
    • 25444483052 scopus 로고    scopus 로고
    • Revisiting the "cdk-centric" view of the mammalian cell cycle
    • Malumbres M. 2005. Revisiting the "cdk-centric" view of the mammalian cell cycle. Cell Cycle, 4:206-10.
    • (2005) Cell Cycle , vol.4 , pp. 206-210
    • Malumbres, M.1
  • 147
    • 33845919935 scopus 로고    scopus 로고
    • The Transformation of Oncology In the Twentieth Century: The Molecularization of Cancer
    • In: Burns CR, O'Neill YV, Albou P, et al eds, Galveston, TX: University of Texas Medical Branch
    • Marcum JA. 2002. The transformation of oncology in the twentieth century: the molecularization of cancer. In: Burns CR, O'Neill YV, Albou P, et al eds. Proceedings of the 37th International Congress on the History of Medicine. Galveston, TX: University of Texas Medical Branch. p 41-9.
    • (2002) Proceedings of the 37th International Congress on the History of Medicine , pp. 41-49
    • Marcum, J.A.1
  • 148
    • 20944437248 scopus 로고    scopus 로고
    • The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase
    • Marcus AI, Zhou J, O'Brate A, et al. 2005. The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase. Cancer Res, 65:3883-93.
    • (2005) Cancer Res , vol.65 , pp. 3883-3893
    • Marcus, A.I.1    Zhou, J.2    O'Brate, A.3
  • 149
    • 33749320934 scopus 로고    scopus 로고
    • Familial breast cancer, underlying genes, and clinical implications: A review
    • Margolin S, Lindblom A. 2006. Familial breast cancer, underlying genes, and clinical implications: a review. Crit Rev Oncog, 12:75-113.
    • (2006) Crit Rev Oncog , vol.12 , pp. 75-113
    • Margolin, S.1    Lindblom, A.2
  • 150
    • 6844252284 scopus 로고    scopus 로고
    • Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
    • Marsh DJ, Coulon V, Lunetta KL, et al. 1998. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum Mol Genet, 7:507-15.
    • (1998) Hum Mol Genet , vol.7 , pp. 507-515
    • Marsh, D.J.1    Coulon, V.2    Lunetta, K.L.3
  • 151
    • 33846781391 scopus 로고    scopus 로고
    • Pharmacogenetics and oncology for breast cancer
    • Marsh S, McLeod HI. 2007. Pharmacogenetics and oncology for breast cancer. Expert Opin Pharmacother, 8:119-27.
    • (2007) Expert Opin Pharmacother , vol.8 , pp. 119-127
    • Marsh, S.1    McLeod, H.I.2
  • 152
    • 33750584024 scopus 로고    scopus 로고
    • Tumour stem cell-targeted treatment: Elimination or differentiation
    • Massard C, Deutsch E, Soria J-C. 2006. Tumour stem cell-targeted treatment: elimination or differentiation. Ann Oncol, 17:1620-4.
    • (2006) Ann Oncol , vol.17 , pp. 1620-1624
    • Massard, C.1    Deutsch, E.2    Soria, J.-C.3
  • 153
    • 33751295869 scopus 로고    scopus 로고
    • Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy
    • Meric-Bernstam F, Hung MC. 2006. Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy. Clin Cancer Res, 12:6326-30.
    • (2006) Clin Cancer Res , vol.12 , pp. 6326-6330
    • Meric-Bernstam, F.1    Hung, M.C.2
  • 154
    • 34247222544 scopus 로고    scopus 로고
    • From menarche to regular menstruation: Endocrinological background
    • Messinis IE. 2006. From menarche to regular menstruation: endocrinological background. Ann N Y Acad Sci, 1092:49-56.
    • (2006) Ann N Y Acad Sci , vol.1092 , pp. 49-56
    • Messinis, I.E.1
  • 155
    • 34250172070 scopus 로고    scopus 로고
    • Diet and breast cancer: A review of the prospective observational studies
    • Michels KB, Mohllajee AP, Roset-Bahmanyar E, et al. 2007. Diet and breast cancer: a review of the prospective observational studies. Cancer, 109:2712-49.
    • (2007) Cancer , vol.109 , pp. 2712-2749
    • Michels, K.B.1    Mohllajee, A.P.2    Roset-Bahmanyar, E.3
  • 156
    • 0031466305 scopus 로고    scopus 로고
    • Cyclin-dependent kinases: Engines, clocks, and micro- processors
    • Morgan DO. 1997. Cyclin-dependent kinases: engines, clocks, and micro- processors. Annu Rev Cell Dev Biol, 13:261-91.
    • (1997) Annu Rev Cell Dev Biol , vol.13 , pp. 261-291
    • Morgan, D.O.1
  • 158
    • 0034964014 scopus 로고    scopus 로고
    • Retinoblastoma protein partners
    • Morris EJ, Dyson NJ. 2001. Retinoblastoma protein partners. Adv Cancer Res, 82:1-54.
    • (2001) Adv Cancer Res , vol.82 , pp. 1-54
    • Morris, E.J.1    Dyson, N.J.2
  • 159
    • 0842287638 scopus 로고    scopus 로고
    • DNA damage tumor suppressor genes and genomic instability
    • Motoyama N, Naka K. 2004. DNA damage tumor suppressor genes and genomic instability. Curr Opin Genet Dev, 14:11-6.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 11-16
    • Motoyama, N.1    Naka, K.2
  • 160
    • 0038460245 scopus 로고    scopus 로고
    • Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: Analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group
    • Mouridesen H, Gershanovich M, Sun Y, et al. 2003. Phase III study of letrozole versus tamoxifen as first-line therapy of advanced breast cancer in postmenopausal women: analysis of survival and update of efficacy from the International Letrozole Breast Cancer Group. J Clin Oncol, 21:2101-9.
    • (2003) J Clin Oncol , vol.21 , pp. 2101-2109
    • Mouridesen, H.1    Gershanovich, M.2    Sun, Y.3
  • 161
    • 33751205030 scopus 로고    scopus 로고
    • Lapatinib: Current status and future directions in breast cancer
    • Moy B, Goss PE. 2006. Lapatinib: current status and future directions in breast cancer. Oncologist, 11:1047-57.
    • (2006) Oncologist , vol.11 , pp. 1047-1057
    • Moy, B.1    Goss, P.E.2
  • 162
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: Cyclins revisited
    • Murray AW. 2004. Recycling the cell cycle: cyclins revisited. Cell, 116:221-34.
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 163
    • 33845887750 scopus 로고    scopus 로고
    • Targeted therapies for metastatic breast cancer
    • Muss HB. 2006. Targeted therapies for metastatic breast cancer. N Engl J Med, 355:2783-5.
    • (2006) N Engl J Med , vol.355 , pp. 2783-2785
    • Muss, H.B.1
  • 164
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • Nagata Y, Lan KH, Zhou X, et al. 2004. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell, 6:117-27.
    • (2004) Cancer Cell , vol.6 , pp. 117-127
    • Nagata, Y.1    Lan, K.H.2    Zhou, X.3
  • 165
    • 34249672864 scopus 로고    scopus 로고
    • Trastuzumab: Triumphs and tribulations
    • Nahta R, Esteva FJ. 2007. Trastuzumab: triumphs and tribulations. Onco- gene, 26:3637-43.
    • (2007) Onco- Gene , vol.26 , pp. 3637-3643
    • Nahta, R.1    Esteva, F.J.2
  • 166
    • 0030966691 scopus 로고    scopus 로고
    • Defining a role for c-Myc in breast tumorigen- esis
    • Nass SJ, Dickson RB. 1997. Defining a role for c-Myc in breast tumorigen- esis. Breast Cancer Res Treat, 44:1-22.
    • (1997) Breast Cancer Res Treat , vol.44 , pp. 1-22
    • Nass, S.J.1    Dickson, R.B.2
  • 167
    • 0035030368 scopus 로고    scopus 로고
    • Breast cancer genetics: What we know and what we need
    • Nathanson KL, Wooster R, Weber BL. 2001. Breast cancer genetics: what we know and what we need. Nat Med, 7:552-6.
    • (2001) Nat Med , vol.7 , pp. 552-556
    • Nathanson, K.L.1    Wooster, R.2    Weber, B.L.3
  • 169
    • 33644860571 scopus 로고    scopus 로고
    • Tumor suppressor genes in breast cancer: The gatekeepers and the caretakers
    • Oliveira AM, Ross JS, Fletcher JA. 2005. Tumor suppressor genes in breast cancer: the gatekeepers and the caretakers. Am J Clin Pathol, 124(Suppl 1):S16-28.
    • (2005) Am J Clin Pathol , vol.124 , Issue.1 SUPPL.
    • Oliveira, A.M.1    Ross, J.S.2    Fletcher, J.A.3
  • 170
    • 3042581811 scopus 로고    scopus 로고
    • Farnesyl transferase inhibitors: The next targeted therapies for breast cancer?
    • O'Regan RM, Khuri FR. 2004. Farnesyl transferase inhibitors: the next targeted therapies for breast cancer? Endocr Relat Cancer, 11:191-205.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 191-205
    • O'Regan, R.M.1    Khuri, F.R.2
  • 171
    • 33646462047 scopus 로고    scopus 로고
    • Chemoprevention of breast cancer
    • O'Regan RM. 2006. Chemoprevention of breast cancer. Lancet, 367:1382-3.
    • (2006) Lancet , vol.367 , pp. 1382-1383
    • O'Regan, R.M.1
  • 172
    • 3542995667 scopus 로고    scopus 로고
    • Oncogenes and tumor suppressor genes in breast cancer: Potential diagnostic and therapeutic applications
    • Osborne C, Wilson P, Tripathy D. 2004. Oncogenes and tumor suppressor genes in breast cancer: potential diagnostic and therapeutic applications. Oncologist, 9:361-77.
    • (2004) Oncologist , vol.9 , pp. 361-377
    • Osborne, C.1    Wilson, P.2    Tripathy, D.3
  • 174
    • 4544223402 scopus 로고    scopus 로고
    • The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome
    • Panigrahi AR, Pinder SE, Chan SY, et al. 2004. The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome. J Pathol, 204:93-100.
    • (2004) J Pathol , vol.204 , pp. 93-100
    • Panigrahi, A.R.1    Pinder, S.E.2    Chan, S.Y.3
  • 176
    • 0034796054 scopus 로고    scopus 로고
    • Recent advances in molecular genetics of breast cancer
    • Pavelić K, Gall-Trošelj K. 2001. Recent advances in molecular genetics of breast cancer. J Mol Med, 79:566-73.
    • (2001) J Mol Med , vol.79 , pp. 566-573
    • Pavelić, K.1    Gall-Trošelj, K.2
  • 177
    • 15544377959 scopus 로고    scopus 로고
    • Targeted therapy: Wave if the future
    • Pegram MD, Pietras R, Bajamonde A, et al. 2005. Targeted therapy: wave if the future. J Clin Oncol, 23:1776-81.
    • (2005) J Clin Oncol , vol.23 , pp. 1776-1781
    • Pegram, M.D.1    Pietras, R.2    Bajamonde, A.3
  • 179
    • 0034680102 scopus 로고    scopus 로고
    • Molecular portraits of human breast tumors
    • Perou CM, Sørlie T, Elsen MB, et al. 2000. Molecular portraits of human breast tumors. Nature, 406:747-52.
    • (2000) Nature , vol.406 , pp. 747-752
    • Perou, C.M.1    Sørlie, T.2    Elsen, M.B.3
  • 180
    • 0035721657 scopus 로고    scopus 로고
    • PTEN deficiency: A role in mammary carcinogenesis
    • Petrocelli T, Slingerland JM. 2001. PTEN deficiency: a role in mammary carcinogenesis. Breast Cancer Res, 3:356-60.
    • (2001) Breast Cancer Res , vol.3 , pp. 356-360
    • Petrocelli, T.1    Slingerland, J.M.2
  • 181
    • 33746782976 scopus 로고    scopus 로고
    • Adjuvant trastuzumab therapy for HER2-overex- pressing breast cancer: What we know and what we still need to learn
    • Piccart-Gebhart MJ. 2006. Adjuvant trastuzumab therapy for HER2-overex- pressing breast cancer: what we know and what we still need to learn. Eur J Cancer, 42:1715-9.
    • (2006) Eur J Cancer , vol.42 , pp. 1715-1719
    • Piccart-Gebhart, M.J.1
  • 182
    • 34447512756 scopus 로고    scopus 로고
    • Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: The Women's Healthy Eating and Living (WHEL) randomized trial
    • Pierce JP, Natarajan L, Caan BJ, et al. 2007. Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized trial. JAMA, 298:289-98.
    • (2007) JAMA , vol.298 , pp. 289-298
    • Pierce, J.P.1    Natarajan, L.2    Caan, B.J.3
  • 183
    • 21344454219 scopus 로고    scopus 로고
    • In vitro propagation of breast tumorigenic cancer cells with stem/progenitor cell properties
    • Ponti D, Costa A, Zaffaroni N, et al. 2005. In vitro propagation of breast tumorigenic cancer cells with stem/progenitor cell properties. Cancer Res, 65:5506-11.
    • (2005) Cancer Res , vol.65 , pp. 5506-5511
    • Ponti, D.1    Costa, A.2    Zaffaroni, N.3
  • 184
    • 33646938749 scopus 로고    scopus 로고
    • Breast cancer cells: An overview
    • Ponti D, Zaffaroni N, Capelli C, et al. 2005. Breast cancer cells: an overview. Eur J Cancer, 42:1219-24.
    • (2005) Eur J Cancer , vol.42 , pp. 1219-1224
    • Ponti, D.1    Zaffaroni, N.2    Capelli, C.3
  • 185
    • 34547632366 scopus 로고    scopus 로고
    • A multidisciplinary approach to the management of breast cancer, part 1: Prevention and diagnosis
    • Pruthi S, Brandt KR, Degnim AC, et al. 2007. A multidisciplinary approach to the management of breast cancer, part 1: prevention and diagnosis. Mayo Clin Proc, 82:999-1012.
    • (2007) Mayo Clin Proc , vol.82 , pp. 999-1012
    • Pruthi, S.1    Brandt, K.R.2    Degnim, A.C.3
  • 186
    • 1842614292 scopus 로고    scopus 로고
    • Bilateral prophylactic mas- tectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: The PROSE study group
    • Rebbeck TR, Friebel T, Lynch HT, et al. 2004. Bilateral prophylactic mas- tectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE study group. J Clin Oncol, 22:1055-62.
    • (2004) J Clin Oncol , vol.22 , pp. 1055-1062
    • Rebbeck, T.R.1    Friebel, T.2    Lynch, H.T.3
  • 187
    • 0030801275 scopus 로고    scopus 로고
    • Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
    • Rhei E, Kang L, Bogomolniy F, et al. 1997. Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas. Cancer Res, 57:3657-9.
    • (1997) Cancer Res , vol.57 , pp. 3657-3659
    • Rhei, E.1    Kang, L.2    Bogomolniy, F.3
  • 188
    • 34447340945 scopus 로고    scopus 로고
    • Management of an inherited predisposition to breast cancer
    • Robson M, Offit K. 2007. Management of an inherited predisposition to breast cancer. N Eng J Med, 357:154-62.
    • (2007) N Eng J Med , vol.357 , pp. 154-162
    • Robson, M.1    Offit, K.2
  • 189
    • 0038274767 scopus 로고    scopus 로고
    • How to target estrogen receptor-negative breast cancer?
    • Rochefort H, Glondu M, Sahla ME, et al. 2003. How to target estrogen receptor-negative breast cancer? Endocr Relat Cancer, 10:261-6.
    • (2003) Endocr Relat Cancer , vol.10 , pp. 261-266
    • Rochefort, H.1    Glondu, M.2    Sahla, M.E.3
  • 191
    • 0031759864 scopus 로고    scopus 로고
    • The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
    • Ross JS, Fletcher JA. 1998. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Stem Cells, 16:413-28.
    • (1998) Stem Cells , vol.16 , pp. 413-428
    • Ross, J.S.1    Fletcher, J.A.2
  • 192
    • 0042208398 scopus 로고    scopus 로고
    • The HER-2/neu gene and protein in breast cancer 2003: Biomarkers and target of therapy
    • Ross JS, Fletcher JA, Linette GP, et al. 2003. The HER-2/neu gene and protein in breast cancer 2003: biomarkers and target of therapy. Oncologist, 8:307-25.
    • (2003) Oncologist , vol.8 , pp. 307-325
    • Ross, J.S.1    Fletcher, J.A.2    Linette, G.P.3
  • 193
    • 2542638621 scopus 로고    scopus 로고
    • Targeted therapy in breast cancer: The HER-2/neu gene and protein
    • Ross JS, Fletcher JA, Bloom KJ, et al. 2004a. Targeted therapy in breast cancer: the HER-2/neu gene and protein. Mol Cell Proteomics, 3:379-98.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 379-398
    • Ross, J.S.1    Fletcher, J.A.2    Bloom, K.J.3
  • 194
    • 1542358118 scopus 로고    scopus 로고
    • Breast cancer biomarkers and molecular medicine
    • Ross JS, Linette GP, Stec J, et al. 2004b. Breast cancer biomarkers and molecular medicine. Expert Rev Mol Diagn, 4:169-88.
    • (2004) Expert Rev Mol Diagn , vol.4 , pp. 169-188
    • Ross, J.S.1    Linette, G.P.2    Stec, J.3
  • 195
    • 33751182887 scopus 로고    scopus 로고
    • Cyclin D1 and breast cancer
    • Roy PG, Thompson AM. 2006. Cyclin D1 and breast cancer. Breast, 15:718-27.
    • (2006) Breast , vol.15 , pp. 718-727
    • Roy, P.G.1    Thompson, A.M.2
  • 196
    • 33750975372 scopus 로고    scopus 로고
    • The role of estrogen in the initiation of breast cancer
    • Russo J, Russo IH. 2006. The role of estrogen in the initiation of breast cancer. J Steroid Biochem Mol Biol, 102:89-96.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 89-96
    • Russo, J.1    Russo, I.H.2
  • 197
    • 0029917720 scopus 로고    scopus 로고
    • Myc oncogenes: The enigmatic family
    • Ryan KM, Birnie GD. 1996. Myc oncogenes: the enigmatic family. Biochem J, 314:713-21.
    • (1996) Biochem J , vol.314 , pp. 713-721
    • Ryan, K.M.1    Birnie, G.D.2
  • 198
    • 17044414424 scopus 로고    scopus 로고
    • New insights into cyclins, CDKs, and cell cycle control
    • Sánchez I, Dynlacht BD. 2005. New insights into cyclins, CDKs, and cell cycle control. Semin Cell Dev Biol, 16:311-21.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 311-321
    • Sánchez, I.1    Dynlacht, B.D.2
  • 199
    • 0036180120 scopus 로고    scopus 로고
    • Molecular aspects of the mammalian cell cycle and cancer
    • Sandal T. 2002. Molecular aspects of the mammalian cell cycle and cancer. Oncologist, 7:73-81.
    • (2002) Oncologist , vol.7 , pp. 73-81
    • Sandal, T.1
  • 200
    • 0032197092 scopus 로고    scopus 로고
    • The cell cycle: A review
    • Schafer KA. 1998. The cell cycle: a review. Vet Pathol, 35:461-78.
    • (1998) Vet Pathol , vol.35 , pp. 461-478
    • Schafer, K.A.1
  • 201
    • 0036498727 scopus 로고    scopus 로고
    • Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers
    • Scheuer L, Kauff N, Robson M, et al. 2002. Outcome of preventive surgery and screening for breast and ovarian cancer in BRCA mutation carriers. J Clin Oncol, 20:1260-8.
    • (2002) J Clin Oncol , vol.20 , pp. 1260-1268
    • Scheuer, L.1    Kauff, N.2    Robson, M.3
  • 202
    • 84900916990 scopus 로고    scopus 로고
    • Molecular Biology of Human Cancers
    • Dordrecht: Springer
    • Schulz WA. 2006. Molecular biology of human cancers. an advanced student's textbook. Dordrecht: Springer.
    • (2006) An advanced student's textbook
    • Schulz, W.A.1
  • 203
    • 0037297135 scopus 로고    scopus 로고
    • Statins can inhibit proliferation of human breast cancer cells in vitro
    • Seeger H, Wallwiener D, Mueck AO. 2003. Statins can inhibit proliferation of human breast cancer cells in vitro. Exp Clin Endocrinol Diabetes, 111:47-8.
    • (2003) Exp Clin Endocrinol Diabetes , vol.111 , pp. 47-48
    • Seeger, H.1    Wallwiener, D.2    Mueck, A.O.3
  • 204
    • 4043180004 scopus 로고    scopus 로고
    • The promise of targeted therapy: Cancer drugs become more specific
    • Segota E, Bukowski RM. 2004. The promise of targeted therapy: cancer drugs become more specific. Cleve Clin J Med, 71:551-60.
    • (2004) Cleve Clin J Med , vol.71 , pp. 551-560
    • Segota, E.1    Bukowski, R.M.2
  • 205
    • 0242708738 scopus 로고    scopus 로고
    • Small-molecular cyclin-dependent kinase modula- tors
    • Senderowicz AM. 2003. Small-molecular cyclin-dependent kinase modula- tors. Oncogene, 22:6609-20.
    • (2003) Oncogene , vol.22 , pp. 6609-6620
    • Senderowicz, A.M.1
  • 206
    • 3142628461 scopus 로고    scopus 로고
    • Targeted therapy: Ready for prime time?
    • Seynaeve C, Verweij J. 2004. Targeted therapy: ready for prime time? Cancer Treat Res, 120:1-15.
    • (2004) Cancer Treat Res , vol.120 , pp. 1-15
    • Seynaeve, C.1    Verweij, J.2
  • 207
    • 33746836894 scopus 로고    scopus 로고
    • Targeted therapy of cancer: New prospects of antibodies and immunoconjugates
    • Sharkey RM, Goldenberg DM. 2006. Targeted therapy of cancer: new prospects of antibodies and immunoconjugates. CA Cancer J Clin, 56:226-43.
    • (2006) CA Cancer J Clin , vol.56 , pp. 226-243
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 208
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. 1996. Cancer cell cycles. Science, 274:1672-7.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 209
    • 0034660892 scopus 로고    scopus 로고
    • Cancer cell cycle revisited
    • Sherr CJ. 2000. Cancer cell cycle revisited. Cancer Res, 60:3689-95.
    • (2000) Cancer Res , vol.60 , pp. 3689-3695
    • Sherr, C.J.1
  • 210
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr CJ. 2004. Principles of tumor suppression. Cell, 116:235-46.
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 211
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. 1999. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev, 13:1501-12.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 212
    • 8644219655 scopus 로고    scopus 로고
    • Living with and without cyclins and cyclin- dependent kinases
    • Sherr CJ, Roberts JM. 2004. Living with and without cyclins and cyclin- dependent kinases. Genes Dev, 18:2699-711.
    • (2004) Genes Dev , vol.18 , pp. 2699-2711
    • Sherr, C.J.1    Roberts, J.M.2
  • 213
    • 17644367566 scopus 로고    scopus 로고
    • H-Ras-specific activation of Rac- MKK3/6-p38 pathway: Its critical role in invasion and migration of breast epithelial cells
    • Shin I, Kim S, Song H, et al. 2005. H-Ras-specific activation of Rac- MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells. J Biol Chem, 280:14675-83.
    • (2005) J Biol Chem , vol.280 , pp. 14675-14683
    • Shin, I.1    Kim, S.2    Song, H.3
  • 214
    • 19344366282 scopus 로고    scopus 로고
    • pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia
    • Simin K, Wu H, Lu L, et al. 2004. pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia. PLoS Biol, 2:194-205.
    • (2004) PLoS Biol , vol.2 , pp. 194-205
    • Simin, K.1    Wu, H.2    Lu, L.3
  • 215
    • 0035835824 scopus 로고    scopus 로고
    • PTEN: Life as a tumor suppressor
    • Simpson L, Parsons R. 2001. PTEN: life as a tumor suppressor. Exp Cell Res, 264:29-41.
    • (2001) Exp Cell Res , vol.264 , pp. 29-41
    • Simpson, L.1    Parsons, R.2
  • 216
    • 0035496625 scopus 로고    scopus 로고
    • Breast cancer in the clinic: Treatments past, treatments future
    • Sledge GW Jr. 2001. Breast cancer in the clinic: treatments past, treatments future. J Mammary Gland Biol Neoplasia, 6:487-95.
    • (2001) J Mammary Gland Biol Neoplasia , vol.6 , pp. 487-495
    • Sledge Jr., G.W.1
  • 217
    • 15544389968 scopus 로고    scopus 로고
    • What is targeted therapy?
    • Sledge GW Jr. 2005. What is targeted therapy? J Clin Oncol, 23:1614-5.
    • (2005) J Clin Oncol , vol.23 , pp. 1614-1615
    • Sledge Jr., G.W.1
  • 218
    • 0041346051 scopus 로고    scopus 로고
    • Exploiting the hallmarks of cancer: The future conquest of breast cancer
    • Sledge GW Jr, Miller KD. 2003. Exploiting the hallmarks of cancer: the future conquest of breast cancer. Eur J Cancer, 39:1668-75.
    • (2003) Eur J Cancer , vol.39 , pp. 1668-1675
    • Sledge Jr., G.W.1    Miller, K.D.2
  • 220
    • 0033012762 scopus 로고    scopus 로고
    • Shc dominant negative disrupts cell cycle progression in both G0-G1 and G2-M of ErbB2-positive breast cancer cells
    • Stevenson LE, Ravichandran KS, Frackelton AR Jr. 1999. Shc dominant negative disrupts cell cycle progression in both G0-G1 and G2-M of ErbB2-positive breast cancer cells. Cell Growth Differ, 10:61-71.
    • (1999) Cell Growth Differ , vol.10 , pp. 61-71
    • Stevenson, L.E.1    Ravichandran, K.S.2    Frackelton Jr., A.R.3
  • 222
    • 0037117550 scopus 로고    scopus 로고
    • A DNA vector-based RNAi technol- ogy to suppress gene expression in mammalian cells
    • Sui G, Soohoo C, Affar EB, et al. 2002. A DNA vector-based RNAi technol- ogy to suppress gene expression in mammalian cells. Proc Natl Acad Sci USA, 99:5515-20.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 5515-5520
    • Sui, G.1    Soohoo, C.2    Affar, E.B.3
  • 223
    • 14644439858 scopus 로고    scopus 로고
    • Recent developments in critical genes in the molecular biology of breast cancer
    • Sunpaweravong S, Sunpaweravong P. 2005. Recent developments in critical genes in the molecular biology of breast cancer. Asian J Surg, 28:71-5.
    • (2005) Asian J Surg , vol.28 , pp. 71-75
    • Sunpaweravong, S.1    Sunpaweravong, P.2
  • 225
    • 85047687410 scopus 로고    scopus 로고
    • The mutant p53-confor- mation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein
    • Takimoto R, Wang W, Dicker DT, et al. 2002. The mutant p53-confor- mation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein. Cancer Biol Ther, 1:47-55.
    • (2002) Cancer Biol Ther , vol.1 , pp. 47-55
    • Takimoto, R.1    Wang, W.2    Dicker, D.T.3
  • 226
    • 0033520712 scopus 로고    scopus 로고
    • PTEN gene and integrin signaling in cancer
    • Tamura M, Gu J, Tran H, et al. 1999. PTEN gene and integrin signaling in cancer. J Natl Cancer Inst, 1:1820-8.
    • (1999) J Natl Cancer Inst , vol.1 , pp. 1820-1828
    • Tamura, M.1    Gu, J.2    Tran, H.3
  • 227
    • 33845270990 scopus 로고    scopus 로고
    • Regulating the p53 pathway: In vitro hypothesis, in vivo veritas
    • Toledo F, Wahl GM. 2006. Regulating the p53 pathway: in vitro hypothesis, in vivo veritas. Nat Rev, 6:909-23.
    • (2006) Nat Rev , vol.6 , pp. 909-923
    • Toledo, F.1    Wahl, G.M.2
  • 228
    • 33750521806 scopus 로고    scopus 로고
    • Low expression of HER2 pro- tein in breast cancer is biologically significant
    • Tovey SM, Reeves JR, Stanton P, et al. 2006. Low expression of HER2 pro- tein in breast cancer is biologically significant. J Pathol, 210:358-62.
    • (2006) J Pathol , vol.210 , pp. 358-362
    • Tovey, S.M.1    Reeves, J.R.2    Stanton, P.3
  • 229
    • 15944398628 scopus 로고    scopus 로고
    • Targeted therapies in breast cancer
    • Tripathy D. 2005. Targeted therapies in breast cancer. Breast J, 11(Suppl 1): S30-5.
    • (2005) Breast J , vol.11 , Issue.1 SUPPL.
    • Tripathy, D.1
  • 230
    • 33846569938 scopus 로고    scopus 로고
    • Targeting mammalian target of rapamy- cin (mTOR) for health and disease
    • Tsang CK, Qi H, Liu LF, et al. 2007. Targeting mammalian target of rapamy- cin (mTOR) for health and disease. Drug Discov Today, 12:112-24.
    • (2007) Drug Discov Today , vol.12 , pp. 112-124
    • Tsang, C.K.1    Qi, H.2    Liu, L.F.3
  • 231
    • 21644482340 scopus 로고    scopus 로고
    • Targeting the DNA repair defect in BRCA tumours
    • Turner N, Tutt A, Ashworth A. 2005. Targeting the DNA repair defect in BRCA tumours. Curr Opin Pharmacol, 5:388-93.
    • (2005) Curr Opin Pharmacol , vol.5 , pp. 388-393
    • Turner, N.1    Tutt, A.2    Ashworth, A.3
  • 232
    • 0036905483 scopus 로고    scopus 로고
    • The dynamics of cell cycle regulation
    • Tyson JJ, Csikasz-Nagy A, Novak B. 2002. The dynamics of cell cycle regulation. BioEssays, 24:1095-1109.
    • (2002) BioEssays , vol.24 , pp. 1095-1109
    • Tyson, J.J.1    Csikasz-Nagy, A.2    Novak, B.3
  • 234
    • 0037169354 scopus 로고    scopus 로고
    • Cancer susceptibility and the functions of BRCA1 and BRCA2
    • Venkitaraman AR. 2002. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell, 108:171-82.
    • (2002) Cell , vol.108 , pp. 171-182
    • Venkitaraman, A.R.1
  • 235
    • 0038052805 scopus 로고    scopus 로고
    • The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer
    • Vermeulen K, van Bockstaele DR, Berneman ZN. 2003. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif, 36:131-49.
    • (2003) Cell Prolif , vol.36 , pp. 131-149
    • Vermeulen, K.1    van Bockstaele, D.R.2    Berneman, Z.N.3
  • 236
    • 18144399578 scopus 로고    scopus 로고
    • mTOR-targeted therapy of cancer with rapamycin derivatives
    • Vignot S, Faivre S, Aguirre D, et al. 2005. mTOR-targeted therapy of cancer with rapamycin derivatives. Ann Oncol, 16:525-37.
    • (2005) Ann Oncol , vol.16 , pp. 525-537
    • Vignot, S.1    Faivre, S.2    Aguirre, D.3    et al4
  • 237
    • 36048988019 scopus 로고    scopus 로고
    • Chemoprevention strategies 2006
    • Vogel VG. 2007. Chemoprevention strategies 2006. Curr Treat Options Oncol, 8:74-88.
    • (2007) Curr Treat Options Oncol , vol.8 , pp. 74-88
    • Vogel, V.G.1
  • 238
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. 2004. Cancer genes and the pathways they control. Nat Med, 10:789-99.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 240
    • 0036206130 scopus 로고    scopus 로고
    • Protean PTEN: Form and function
    • Waite KA, Eng C. 2002. Protean PTEN: form and function. Am J Hum Genet, 70:829-44.
    • (2002) Am J Hum Genet , vol.70 , pp. 829-844
    • Waite, K.A.1    Eng, C.2
  • 241
    • 33846850422 scopus 로고    scopus 로고
    • Ten genes for inherited breast cancer
    • Walsh T, King MC. 2007. Ten genes for inherited breast cancer. Cancer Cell, 11:103-5.
    • (2007) Cancer Cell , vol.11 , pp. 103-105
    • Walsh, T.1    King, M.C.2
  • 242
    • 33645651433 scopus 로고    scopus 로고
    • A phase II trial with trastuzumab and pertuzumab in patients with HER2-overexpressed locally advanced and metastatic breast cancer
    • Walshe JM, Denduluri N, Berman AW, et al. 2006. A phase II trial with trastuzumab and pertuzumab in patients with HER2-overexpressed locally advanced and metastatic breast cancer. Clin Breast Cancer, 6:535-9.
    • (2006) Clin Breast Cancer , vol.6 , pp. 535-539
    • Walshe, J.M.1    Denduluri, N.2    Berman, A.W.3
  • 243
  • 244
    • 23844448634 scopus 로고    scopus 로고
    • Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo
    • Wang Y, Liu S, Zhang G, et al. 2005. Knockdown of c-Myc expression by RNAi inhibits MCF-7 breast tumor cells growth in vitro and in vivo. Breast Cancer Res, 7:R220-8.
    • (2005) Breast Cancer Res , vol.7
    • Wang, Y.1    Liu, S.2    Zhang, G.3
  • 245
    • 33748631834 scopus 로고    scopus 로고
    • Effect of a farnesyl transferase inhibitor (R115777) on ductal carcinoma in situ of the breast in a human xenograft model and on breast and ovarian cancer cell growth in vitro and in vivo
    • Wärnberg F, White D, Anderson E, et al. 2006. Effect of a farnesyl transferase inhibitor (R115777) on ductal carcinoma in situ of the breast in a human xenograft model and on breast and ovarian cancer cell growth in vitro and in vivo. Breast Cancer Res, 8(2):R21-30.
    • (2006) Breast Cancer Res , vol.8 , Issue.2
    • Wärnberg, F.1    White, D.2    Anderson, E.3
  • 246
    • 0026377424 scopus 로고
    • Inhibition of c-myc expression by phophorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer
    • Watson PH, Pon RT, Shiu RPC. 1991. Inhibition of c-myc expression by phophorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer. Cancer Res, 51:3996-4000.
    • (1991) Cancer Res , vol.51 , pp. 3996-4000
    • Watson, P.H.1    Pon, R.T.2    Shiu, R.P.C.3
  • 248
    • 0033571477 scopus 로고    scopus 로고
    • PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death
    • Weng LP, Smith WM, Dahia PLM, et al. 1999. PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death. Cancer Res, 59:5808-14.
    • (1999) Cancer Res , vol.59 , pp. 5808-5814
    • Weng, L.P.1    Smith, W.M.2    Dahia, P.L.M.3
  • 249
    • 0346327392 scopus 로고    scopus 로고
    • Dual action of cyclin- dependent kinase inhibitors: Induction of cell cycle arrest and apoptosis: A comparison of the effects exerted by roscovitine and cisplatin
    • Wesierska-Gadek J, Gueorguieva M, Horky M. 2003. Dual action of cyclin- dependent kinase inhibitors: induction of cell cycle arrest and apoptosis: a comparison of the effects exerted by roscovitine and cisplatin. Pol J Pharmacol, 55:895-902.
    • (2003) Pol J Pharmacol , vol.55 , pp. 895-902
    • Wesierska-Gadek, J.1    Gueorguieva, M.2    Horky, M.3
  • 250
    • 0029281412 scopus 로고
    • The retinoblastoma protein and its relatives
    • Whyte P. 1995. The retinoblastoma protein and its relatives. Semin Cancer Biol, 6:83-90.
    • (1995) Semin Cancer Biol , vol.6 , pp. 83-90
    • Whyte, P.1
  • 251
    • 33644560281 scopus 로고    scopus 로고
    • Cancer stem cells: An old idea - a para- digm shift
    • Wicha MS, Liu S, Dontu G. 2006. Cancer stem cells: an old idea - a para- digm shift. Cancer Res, 66:1883-90.
    • (2006) Cancer Res , vol.66 , pp. 1883-1890
    • Wicha, M.S.1    Liu, S.2    Dontu, G.3
  • 252
    • 0037052448 scopus 로고    scopus 로고
    • Stromal effects on mammary gland develop- ment and breast cancer
    • Wiseman BS, Werb Z. 2002. Stromal effects on mammary gland develop- ment and breast cancer. Science, 296:1046-9.
    • (2002) Science , vol.296 , pp. 1046-1049
    • Wiseman, B.S.1    Werb, Z.2
  • 253
    • 0038575385 scopus 로고    scopus 로고
    • Expression of the HER1-4 fam- ily of receptor tyrosine kinases in breast cancer
    • Witton CJ, Reeves JR, Going JJ, et al. 2003. Expression of the HER1-4 fam- ily of receptor tyrosine kinases in breast cancer. J Pathol, 200:290-7.
    • (2003) J Pathol , vol.200 , pp. 290-297
    • Witton, C.J.1    Reeves, J.R.2    Going, J.J.3
  • 254
    • 3242665918 scopus 로고    scopus 로고
    • Do female sex hormones initiate breast cancer? A review of the evidence
    • Wren BG. 2004. Do female sex hormones initiate breast cancer? A review of the evidence. Climacteric, 7:120-8.
    • (2004) Climacteric , vol.7 , pp. 120-128
    • Wren, B.G.1
  • 255
    • 83255182384 scopus 로고    scopus 로고
    • Early references to the mutational origin of cancer
    • Wunderlich V. 2006. Early references to the mutational origin of cancer. Int J Epidemiol, 14:1-2.
    • (2006) Int J Epidemiol , vol.14 , pp. 1-2
    • Wunderlich, V.1
  • 257
    • 0037385703 scopus 로고    scopus 로고
    • Advancements of antisense oligonucle- otides in treatment of breast cancer
    • Yang SP, Song ST, Song HF. 2003. Advancements of antisense oligonucle- otides in treatment of breast cancer. Acta Pharmacol Sin, 24:289-95.
    • (2003) Acta Pharmacol Sin , vol.24 , pp. 289-295
    • Yang, S.P.1    Song, S.T.2    Song, H.F.3
  • 258
    • 33746050405 scopus 로고    scopus 로고
    • BRCA1 at the crossroads of multiple cellular pathways: Approaches for therapeutic interventions
    • Yarden RI, Papa MZ. 2006. BRCA1 at the crossroads of multiple cellular pathways: approaches for therapeutic interventions. Mol Cancer Ther, 5:1396-404.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1396-1404
    • Yarden, R.I.1    Papa, M.Z.2
  • 260
    • 0035835815 scopus 로고    scopus 로고
    • The retinoblastoma gene: A prototypic and mul- tifunctional tumor suppressor
    • Zheng L, Lee WH. 2001. The retinoblastoma gene: a prototypic and mul- tifunctional tumor suppressor. Exp Cell Res, 264:2-18.
    • (2001) Exp Cell Res , vol.264 , pp. 2-18
    • Zheng, L.1    Lee, W.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.