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Volumn 9, Issue SUPPL. 3, 2004, Pages 10-15

Dual kinase inhibition in the treatment of breast cancer: Initial experience with the EGFR/ErbB-2 inhibitor lapatinib

Author keywords

Capecitabine; EGFR; HER 2; Letrozole; Paclitaxel; Quinazoline; Trastuzumab; Tyrosine kinase inhibitor

Indexed keywords

CAPECITABINE; DNA NUCLEOTIDYLEXOTRANSFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; LAPATINIB; LETROZOLE; PROTEIN TYROSINE KINASE INHIBITOR; TRASTUZUMAB;

EID: 2942592008     PISSN: 10837159     EISSN: None     Source Type: Journal    
DOI: 10.1634/theoncologist.9-suppl_3-10     Document Type: Review
Times cited : (284)

References (11)
  • 1
    • 0031936410 scopus 로고    scopus 로고
    • Specificity within the EGF family/ErbB receptor family signaling network
    • Riese DJ 2nd, Stem DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998;20:41-48.
    • (1998) Bioessays , vol.20 , pp. 41-48
    • Riese II, D.J.1    Stem, D.F.2
  • 2
    • 0032510109 scopus 로고    scopus 로고
    • Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes
    • Amundadottir LT, Leder P. Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes. Oncogene 1998;16:737-746.
    • (1998) Oncogene , vol.16 , pp. 737-746
    • Amundadottir, L.T.1    Leder, P.2
  • 3
    • 0034613381 scopus 로고    scopus 로고
    • Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation
    • Okano J, Gaslightwala I, Birnbaum MJ et al. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation. J Biol Chem 2000;275:30934-30942.
    • (2000) J Biol Chem , vol.275 , pp. 30934-30942
    • Okano, J.1    Gaslightwala, I.2    Birnbaum, M.J.3
  • 4
    • 0034600849 scopus 로고    scopus 로고
    • The ErbB signaling network: Receptor heterodimerization in development and cancer
    • Olayioye MA, Neve RM, Lane HA et al. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000;19:3159-3167.
    • (2000) EMBO J , vol.19 , pp. 3159-3167
    • Olayioye, M.A.1    Neve, R.M.2    Lane, H.A.3
  • 5
    • 0033992633 scopus 로고    scopus 로고
    • Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors
    • Klapper LN, Kirschbaum MH, Sela M et al. Biochemical and clinical implications of the ErbB/HER signaling network of growth factor receptors. Adv Cancer Res 2000;77:25-79.
    • (2000) Adv Cancer Res , vol.77 , pp. 25-79
    • Klapper, L.N.1    Kirschbaum, M.H.2    Sela, M.3
  • 6
    • 0035893560 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
    • Moulder SL, Yakes FM, Muthuswamy SK et al. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res 2001;61:8887-8895.
    • (2001) Cancer Res , vol.61 , pp. 8887-8895
    • Moulder, S.L.1    Yakes, F.M.2    Muthuswamy, S.K.3
  • 7
    • 2942570645 scopus 로고    scopus 로고
    • A novel strategy of colon cancer therapy: Targeting both EGFR and ErbB2 receptors
    • Abstract 5529
    • Zhou Y, Brattain M. A novel strategy of colon cancer therapy: targeting both EGFR and ErbB2 receptors. Proc Am Assoc Cancer Res 2003; 1267. Abstract 5529.
    • (2003) Proc Am Assoc Cancer Res , vol.1267
    • Zhou, Y.1    Brattain, M.2
  • 8
    • 0035476866 scopus 로고    scopus 로고
    • The characterization of novel, dual erbB-2/EGFR, tyrosine kinase inhibitors: Potential therapy for cancer
    • Rusnak DW, Affleck K, Cockerill SG et al. The characterization of novel, dual erbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer. Cancer Res 2001;61:7196-7203.
    • (2001) Cancer Res , vol.61 , pp. 7196-7203
    • Rusnak, D.W.1    Affleck, K.2    Cockerill, S.G.3
  • 9
    • 0037068741 scopus 로고    scopus 로고
    • Anti-tumor activity of GW572016: A dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways
    • Xia W, Mullin RJ, Keith BR et al. Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways. Oncogene 2002;21:6255-6263.
    • (2002) Oncogene , vol.21 , pp. 6255-6263
    • Xia, W.1    Mullin, R.J.2    Keith, B.R.3
  • 10
    • 0141819721 scopus 로고    scopus 로고
    • A phase I study of GW572016 in patients with solid tumors
    • Burris HA, Taylor C, Jones S et al. A phase I study of GW572016 in patients with solid tumors. Proc Am Soc Clin Oncol 2003;22:258.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 258
    • Burris, H.A.1    Taylor, C.2    Jones, S.3
  • 11
    • 0344341539 scopus 로고    scopus 로고
    • Safety, clinical efficacy, and biologic assessments from EGF10004: A randomized phase IB study of GW572016 for patients with metastatic carcinomas overexpressing EGFR or erbB2
    • Spector N, Raefsky E, Hurwitz H et al. Safety, clinical efficacy, and biologic assessments from EGF10004: a randomized phase IB study of GW572016 for patients with metastatic carcinomas overexpressing EGFR or erbB2. Proc Am Soc Clin Oncol 2003;22:193.
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 193
    • Spector, N.1    Raefsky, E.2    Hurwitz, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.