-
1
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell PC. The clonal evolution of tumor cell populations. Science 1976;194:23-28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.C.1
-
2
-
-
0030799482
-
Multistep carcinogenesis of breast cancer and tumour heterogeneity
-
Beckmann MW, Niederacher D, Schnurch HG et al. Multistep carcinogenesis of breast cancer and tumour heterogeneity. J Mol Med 1997;75:429-439.
-
(1997)
J Mol Med
, vol.75
, pp. 429-439
-
-
Beckmann, M.W.1
Niederacher, D.2
Schnurch, H.G.3
-
3
-
-
0036876166
-
Molecular alterations in sporadic breast cancer
-
Lerebours F, Lidereau R. Molecular alterations in sporadic breast cancer. Crit Rev Oncol Hematol 2002;44:121-141.
-
(2002)
Crit Rev Oncol Hematol
, vol.44
, pp. 121-141
-
-
Lerebours, F.1
Lidereau, R.2
-
4
-
-
0037370476
-
The genetics and genomics of cancer
-
Balmain A, Gray J, Ponder B. The genetics and genomics of cancer. Nat Genet 2003;33(suppl):238-244.
-
(2003)
Nat Genet
, vol.33
, Issue.SUPPL.
, pp. 238-244
-
-
Balmain, A.1
Gray, J.2
Ponder, B.3
-
5
-
-
0034673232
-
Chromosomal alterations in ductal carcinomas in situ and their in situ recurrences
-
Waldman FM, DeVries S, Chew KL et al. Chromosomal alterations in ductal carcinomas in situ and their in situ recurrences. J Natl Cancer Inst 2000;92:313-320.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 313-320
-
-
Waldman, F.M.1
DeVries, S.2
Chew, K.L.3
-
6
-
-
0032490119
-
Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci
-
O'Connell P, Pekkel V, Fuqua SA et al. Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci. J Natl Cancer Inst 1998;90:697-703.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 697-703
-
-
O'Connell, P.1
Pekkel, V.2
Fuqua, S.A.3
-
7
-
-
0037264633
-
Targeting RAS signaling pathways in cancer therapy
-
Downward J. Targeting RAS signaling pathways in cancer therapy. Nat Rev Cancer 2003;3:11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
8
-
-
0037285971
-
Growth factor receptors in breast cancer: Potential for therapeutic intervention
-
Nahta R, Hortobagyi GN, Esteva FJ. Growth factor receptors in breast cancer: potential for therapeutic intervention. The Oncologist 2003;8:5-17.
-
(2003)
The Oncologist
, vol.8
, pp. 5-17
-
-
Nahta, R.1
Hortobagyi, G.N.2
Esteva, F.J.3
-
9
-
-
0037076342
-
Initiating oncogenic event determines gene-expression patterns of human breast cancer models
-
Desai KV, Xiao N, Wang W et al. Initiating oncogenic event determines gene-expression patterns of human breast cancer models. Proc Natl Acad Sci USA 2002;99:6967-6972.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 6967-6972
-
-
Desai, K.V.1
Xiao, N.2
Wang, W.3
-
11
-
-
0037076002
-
Signal transduction: Molecular ticket to enter cells
-
Oved S, Yarden Y. Signal transduction: molecular ticket to enter cells. Nature 2002;416:133-136.
-
(2002)
Nature
, vol.416
, pp. 133-136
-
-
Oved, S.1
Yarden, Y.2
-
12
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987;235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
13
-
-
0023736334
-
Neu-protein overexpression in breast cancer. Association with comedotype ductal carcinoma in situ and limited prognostic value in stage II breast cancer
-
van de Vijver MJ, Peterse JL, Mooi WJ et al. Neu-protein overexpression in breast cancer. Association with comedotype ductal carcinoma in situ and limited prognostic value in stage II breast cancer. N Engl J Med 1988;319:1239-1245.
-
(1988)
N Engl J Med
, vol.319
, pp. 1239-1245
-
-
Van De Vijver, M.J.1
Peterse, J.L.2
Mooi, W.J.3
-
14
-
-
0042208398
-
The HER-2/neu gene and protein in breast cancer 2003: Biomarker and target of therapy
-
Ross JS, Fletcher JA, Linette GP et al. The HER-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy. The Oncologist 2003;8:307-325.
-
(2003)
The Oncologist
, vol.8
, pp. 307-325
-
-
Ross, J.S.1
Fletcher, J.A.2
Linette, G.P.3
-
15
-
-
0024478054
-
HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
-
HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol Cell Biol 1989;9:1165-1172.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1165-1172
-
-
Hudziak, R.M.1
Lewis, G.D.2
Winget, M.3
-
17
-
-
0034076307
-
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
-
Clynes RA, Towers TL, Presta LG et al. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med 2000;6:443-446.
-
(2000)
Nat Med
, vol.6
, pp. 443-446
-
-
Clynes, R.A.1
Towers, T.L.2
Presta, L.G.3
-
18
-
-
0029991439
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
-
HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol 1996;14:737-744.
-
(1996)
J Clin Oncol
, vol.14
, pp. 737-744
-
-
Baselga, J.1
Tripathy, D.2
Mendelohn, J.3
-
19
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999;17:2639-2648.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
20
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel CL, Cobleigh MA, Tripathy D et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:719-726.
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
21
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001;344:783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
22
-
-
0036316232
-
Trastuzumab cardiotoxicity: Speculations regarding pathophysiology and targets for further study
-
Schneider JW, Chang AY, Garratt A. Trastuzumab cardiotoxicity: speculations regarding pathophysiology and targets for further study. Semin Oncol 2002;29(suppl 11):22-28.
-
(2002)
Semin Oncol
, vol.29
, Issue.SUPPL. 11
, pp. 22-28
-
-
Schneider, J.W.1
Chang, A.Y.2
Garratt, A.3
-
23
-
-
0033118889
-
Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers
-
Pegram M, Hsu S, Lewis G et al. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene 1999;18:2241-2251.
-
(1999)
Oncogene
, vol.18
, pp. 2241-2251
-
-
Pegram, M.1
Hsu, S.2
Lewis, G.3
-
24
-
-
0041885349
-
Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: Multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm
-
Burstein HJ, Harris LN, Marcom PK et al. Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II trial with clinical outcomes, analysis of serum tumor markers as predictive factors, and cardiac surveillance algorithm. J Clin Oncol 2003;21:2889-2895.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2889-2895
-
-
Burstein, H.J.1
Harris, L.N.2
Marcom, P.K.3
-
25
-
-
0036534121
-
Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
-
Esteva FJ, Valero V, Booser D et al. Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer. J Clin Oncol 2002;20:1800-1808.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1800-1808
-
-
Esteva, F.J.1
Valero, V.2
Booser, D.3
-
26
-
-
0037397712
-
Gemcitabine and trastuzumab in metastatic breast cancer
-
O'Shaughnessy J. Gemcitabine and trastuzumab in metastatic breast cancer. Semin Oncol 2003;30(suppl 3):22-26.
-
(2003)
Semin Oncol
, vol.30
, Issue.SUPPL. 3
, pp. 22-26
-
-
O'Shaughnessy, J.1
-
27
-
-
0012643984
-
Phase III randomized comparative study of trastuzumab and paclitaxel with and without carboplatinum in patients with HER2/neu positive advanced breast cancer
-
Robert N, Leyland-Jones B, Asmar L et al. Phase III randomized comparative study of trastuzumab and paclitaxel with and without carboplatinum in patients with HER2/neu positive advanced breast cancer. Breast Cancer Res Treat 2002;76(suppl 1):S37.
-
(2002)
Breast Cancer Res Treat
, vol.76
, Issue.SUPPL. 1
-
-
Robert, N.1
Leyland-Jones, B.2
Asmar, L.3
-
28
-
-
0037241504
-
Integration of signal transduction inhibitors with endocrine therapy: An approach to overcoming hormone resistance in breast cancer
-
Johnston SR, Head J, Pancholi S et al. Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer. Clin Cancer Res 2003;9:524S-532S.
-
(2003)
Clin Cancer Res
, vol.9
-
-
Johnston, S.R.1
Head, J.2
Pancholi, S.3
-
29
-
-
19044380618
-
Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth
-
Agus DB, Akita RW, Fox WD et al. Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth. Cancer Cell 2002;2:127-137.
-
(2002)
Cancer Cell
, vol.2
, pp. 127-137
-
-
Agus, D.B.1
Akita, R.W.2
Fox, W.D.3
-
30
-
-
0347511057
-
Clinical activity in a phase I trial of HER-2-targeted rhuMab 2C4 (pertuzumab) in patients with advanced solid malignancies
-
Agus DB, Gordon M, Taylor C et al. Clinical activity in a phase I trial of HER-2-targeted rhuMab 2C4 (pertuzumab) in patients with advanced solid malignancies. Proc Am Soc Clin Oncol 2003;22:192.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 192
-
-
Agus, D.B.1
Gordon, M.2
Taylor, C.3
-
31
-
-
0038575385
-
Expression of the HER 1-4 family of receptor tyrosine kinases in breast cancer
-
Witton CJ, Reeves JR, Going JJ et al. Expression of the HER 1-4 family of receptor tyrosine kinases in breast cancer. J Pathol 2003;200:290-297.
-
(2003)
J Pathol
, vol.200
, pp. 290-297
-
-
Witton, C.J.1
Reeves, J.R.2
Going, J.J.3
-
32
-
-
0037270588
-
Epidermal growth factor family receptors and inhibitors: Radiation response modulators
-
Sartor CI. Epidermal growth factor family receptors and inhibitors: radiation response modulators. Semin Radiat Oncol 2003;13:22-30.
-
(2003)
Semin Radiat Oncol
, vol.13
, pp. 22-30
-
-
Sartor, C.I.1
-
33
-
-
0002823211
-
Cetuximab plus irinotecan (CPT-11) is active in CPT-11-refractory colorectal cancer that expresses epidermal growth factor receptor
-
Saltz L, Rubin M, Hochster H et al. Cetuximab plus irinotecan (CPT-11) is active in CPT-11-refractory colorectal cancer that expresses epidermal growth factor receptor. Proc Am Soc Clin Oncol 2001;20:3a.
-
(2001)
Proc Am Soc Clin Oncol
, vol.20
-
-
Saltz, L.1
Rubin, M.2
Hochster, H.3
-
34
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J Clin Oncol 2003;21:2787-2799.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
35
-
-
0042675500
-
Open-label, phase II multicenter trial of ZD 1839 ('Iressa') in patients with advanced breast cancer
-
Albain K, Elledge R, Gradishar R et al. Open-label, phase II multicenter trial of ZD 1839 ('Iressa') in patients with advanced breast cancer. Breast Cancer Res Treat 2002;76(suppl 1):S33.
-
(2002)
Breast Cancer Res Treat
, vol.76
, Issue.SUPPL. 1
-
-
Albain, K.1
Elledge, R.2
Gradishar, R.3
-
36
-
-
0042804495
-
Gefitinib (ZD1839) is active in acquired tamoxifen (TAM)-resistant oestrogen receptor (ER)-positive and ER-negative breast cancer: Results from a phase II study
-
Robertson JFR, Gutteridge E, Cheung KL et al. Gefitinib (ZD1839) is active in acquired tamoxifen (TAM)-resistant oestrogen receptor (ER)-positive and ER-negative breast cancer: results from a phase II study. Proc Am Soc Clin Oncol 2003;22:7.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 7
-
-
Robertson, J.F.R.1
Gutteridge, E.2
Cheung, K.L.3
-
37
-
-
0041802378
-
Phase II and tumor pharmacodynamic study of gefinitib (ZD1839) in patients with advanced breast cancer
-
Baselga J, Albanell A, Ruiz A et al. Phase II and tumor pharmacodynamic study of gefinitib (ZD1839) in patients with advanced breast cancer. Proc Am Soc Clin Oncol 2003;22:7.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 7
-
-
Baselga, J.1
Albanell, A.2
Ruiz, A.3
-
38
-
-
0038700004
-
Phase II multicenter study to evaluate the efficacy and safety of Tarceva™ (erlotinib, OSI-774) in women with previously treated locally advanced or metastatic breast cancer
-
Winer E, Cobleigh M, Dickler M et al. Phase II multicenter study to evaluate the efficacy and safety of Tarceva™ (erlotinib, OSI-774) in women with previously treated locally advanced or metastatic breast cancer. Breast Cancer Res Treat 2002;76(suppl 1):S115.
-
(2002)
Breast Cancer Res Treat
, vol.76
, Issue.SUPPL. 1
-
-
Winer, E.1
Cobleigh, M.2
Dickler, M.3
-
39
-
-
0042197413
-
Mammalian target of rapamycin: A new molecular target for breast cancer
-
Mita MM, Mita A, Rowinsky EK. Mammalian target of rapamycin: a new molecular target for breast cancer. Clin Breast Cancer 2003;4:126-137.
-
(2003)
Clin Breast Cancer
, vol.4
, pp. 126-137
-
-
Mita, M.M.1
Mita, A.2
Rowinsky, E.K.3
-
40
-
-
0000183432
-
CCI-779, a rapamycin analogue and multifaceted inhibitor of signal transduction: A phase I study
-
Hidalgo M, Rowinski E, Erlichman C et al. CCI-779, a rapamycin analogue and multifaceted inhibitor of signal transduction: a phase I study. Proc Am Soc Clin Oncol 2000;19:187.
-
(2000)
Proc Am Soc Clin Oncol
, vol.19
, pp. 187
-
-
Hidalgo, M.1
Rowinski, E.2
Erlichman, C.3
-
41
-
-
0042804488
-
Phase 2 study of two dose levels of CCI-779 in locally advanced or metastatic breast cancer failing prior anthracycline and/or taxane
-
Chan S, Scheulen ME, Johnson S et al. Phase 2 study of two dose levels of CCI-779 in locally advanced or metastatic breast cancer failing prior anthracycline and/or taxane. Proc Am Soc Clin Oncol 2003;22:193.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 193
-
-
Chan, S.1
Scheulen, M.E.2
Johnson, S.3
-
42
-
-
0038352147
-
Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer
-
Johnston SR, Hickish T, Ellis P et al. Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer. J Clin Oncol 2003;21:2492-2499.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2492-2499
-
-
Johnston, S.R.1
Hickish, T.2
Ellis, P.3
-
43
-
-
0038052805
-
The cell cycle: A review of regulation, deregulation and therapeutic targets in cancer
-
Vermeulen K, Van Bockstaele DR, Berneman ZN. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 2003;36:131-149.
-
(2003)
Cell Prolif
, vol.36
, pp. 131-149
-
-
Vermeulen, K.1
Van Bockstaele, D.R.2
Berneman, Z.N.3
-
45
-
-
0037063165
-
The cyclin D1 high and cyclin E high subgroups of breast cancer: Separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node
-
Loden M, Stighall M, Nielsen NH et al. The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node. Oncogene 2002;21:4680-4690.
-
(2002)
Oncogene
, vol.21
, pp. 4680-4690
-
-
Loden, M.1
Stighall, M.2
Nielsen, N.H.3
-
46
-
-
0037079027
-
Cyclin E and survival in patients with breast cancer
-
Keyomarsi K, Tucker SL, Buchholz TA et al. Cyclin E and survival in patients with breast cancer. N Engl J Med 2002;347:1566-1575.
-
(2002)
N Engl J Med
, vol.347
, pp. 1566-1575
-
-
Keyomarsi, K.1
Tucker, S.L.2
Buchholz, T.A.3
-
47
-
-
0042303844
-
Cyclin-dependent kinase inhibitors
-
Dai Y, Grant S. Cyclin-dependent kinase inhibitors. Curr Opin Pharmacol 2003;3:362-370.
-
(2003)
Curr Opin Pharmacol
, vol.3
, pp. 362-370
-
-
Dai, Y.1
Grant, S.2
-
48
-
-
0036318722
-
Review of flavopiridol, a cyclin-dependent kinase inhibitor, as breast cancer therapy
-
Tan AR, Swain SM. Review of flavopiridol, a cyclin-dependent kinase inhibitor, as breast cancer therapy. Semin Oncol 2002;29(suppl 11):77-85.
-
(2002)
Semin Oncol
, vol.29
, Issue.SUPPL. 11
, pp. 77-85
-
-
Tan, A.R.1
Swain, S.M.2
-
49
-
-
0038473927
-
Flavopiridol in untreated or relapsed mantle-cell lymphoma: Results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group
-
Kouroukis CT, Belch A, Crump M et al. Flavopiridol in untreated or relapsed mantle-cell lymphoma: results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2003;21:1740-1745.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1740-1745
-
-
Kouroukis, C.T.1
Belch, A.2
Crump, M.3
-
51
-
-
0037089564
-
Rate-limiting effects of Cyclin D1 in transformation by ErbB2 predicts synergy between Herceptin and flavopiridol
-
Nahta R, Iglehart JD, Kempkes B et al. Rate-limiting effects of Cyclin D1 in transformation by ErbB2 predicts synergy between Herceptin and flavopiridol. Cancer Res 2002;62:2267-2271.
-
(2002)
Cancer Res
, vol.62
, pp. 2267-2271
-
-
Nahta, R.1
Iglehart, J.D.2
Kempkes, B.3
-
52
-
-
0042303391
-
A multicenter phase II study of the cell cycle inhibitor Ro 31-7453 in patients with metastatic breast cancer who have failed chemotherapy with an anthmcycline and a taxane
-
Trigo Perez JM, Gil M, Miles D et al. A multicenter phase II study of the cell cycle inhibitor Ro 31-7453 in patients with metastatic breast cancer who have failed chemotherapy with an anthmcycline and a taxane. Proc Am Soc Clin Oncol 2003;22:16.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 16
-
-
Trigo Perez, J.M.1
Gil, M.2
Miles, D.3
-
53
-
-
0347475767
-
A phase 2 study of UCN-01 in advanced renal cell carcinoma
-
Shaw VA, Rini BI, Park JW et al. A phase 2 study of UCN-01 in advanced renal cell carcinoma. Proc Am Soc Clin Oncol 2003;22:442.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 442
-
-
Shaw, V.A.1
Rini, B.I.2
Park, J.W.3
-
54
-
-
0038189900
-
Therapeutic anti-cancer targets upstream of the proteasome
-
Nalepa G, Wade Harper J. Therapeutic anti-cancer targets upstream of the proteasome. Cancer Treat Rev 2003;29(suppl 1):49-57.
-
(2003)
Cancer Treat Rev
, vol.29
, Issue.SUPPL. 1
, pp. 49-57
-
-
Nalepa, G.1
Wade Harper, J.2
-
55
-
-
0142139039
-
Phase I study of bortezomib in combination with docetaxel in anthracycline-pretreated advanced breast cancer
-
Albanell J, Baselga J, Guix M et al. Phase I study of bortezomib in combination with docetaxel in anthracycline-pretreated advanced breast cancer. Proc Am Soc Clin Oncol 2003;22:16.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 16
-
-
Albanell, J.1
Baselga, J.2
Guix, M.3
-
56
-
-
0030966691
-
Defining a role for c-myc in breast tumorigenesis
-
Nass SJ, Dickson RB. Defining a role for c-myc in breast tumorigenesis. Breast Cancer Res Treat 1997;44:1-22.
-
(1997)
Breast Cancer Res Treat
, vol.44
, pp. 1-22
-
-
Nass, S.J.1
Dickson, R.B.2
-
57
-
-
0023618780
-
Alterations to either c-erbB2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis
-
Varley JM, Swallow JE, Brammer WJ et al. Alterations to either c-erbB2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis. Oncogene 1987;1:423-430.
-
(1987)
Oncogene
, vol.1
, pp. 423-430
-
-
Varley, J.M.1
Swallow, J.E.2
Brammer, W.J.3
-
58
-
-
0036606633
-
Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: Implications for the antiproliferative effects of antiestrogens
-
Carroll JS, Swarbrick A, Musgrove EA et al. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. Cancer Res 2002;62:3126-3131.
-
(2002)
Cancer Res
, vol.62
, pp. 3126-3131
-
-
Carroll, J.S.1
Swarbrick, A.2
Musgrove, E.A.3
-
59
-
-
0015043748
-
Mutation and cancer: Statistical study of retinoblastoma
-
Knudson AG Jr. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 1971;68:820-823.
-
(1971)
Proc Natl Acad Sci USA
, vol.68
, pp. 820-823
-
-
Knudson Jr., A.G.1
-
60
-
-
0024452546
-
p53: A frequent target for genetic abnormalities in lung cancer
-
Takahashi T, Nau MM, Chiba I et al. p53: a frequent target for genetic abnormalities in lung cancer. Science 1989;246:491-494.
-
(1989)
Science
, vol.246
, pp. 491-494
-
-
Takahashi, T.1
Nau, M.M.2
Chiba, I.3
-
61
-
-
0024387728
-
Mutations in the p53 gene occur in diverse human tumour types
-
Nigro JM, Baker SJ, Preisinger AC et al. Mutations in the p53 gene occur in diverse human tumour types. Nature 1989;342:705-708.
-
(1989)
Nature
, vol.342
, pp. 705-708
-
-
Nigro, J.M.1
Baker, S.J.2
Preisinger, A.C.3
-
63
-
-
0025633582
-
Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
-
Malkin D, Li FP, Strong LC et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990;250:1233-1238.
-
(1990)
Science
, vol.250
, pp. 1233-1238
-
-
Malkin, D.1
Li, F.P.2
Strong, L.C.3
-
64
-
-
0025395704
-
Familial cancer syndromes and clusters
-
Li FP. Familial cancer syndromes and clusters. Curr Probl Cancer 1990;14:73-114.
-
(1990)
Curr Probl Cancer
, vol.14
, pp. 73-114
-
-
Li, F.P.1
-
65
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
67
-
-
0034096190
-
p53 regulates the expression of the tumor suppressor gene maspin
-
Zou Z, Gao C, Nagaich AK et al. p53 regulates the expression of the tumor suppressor gene maspin. J Biol Chem 2000;275:6051-6054.
-
(2000)
J Biol Chem
, vol.275
, pp. 6051-6054
-
-
Zou, Z.1
Gao, C.2
Nagaich, A.K.3
-
68
-
-
0029014425
-
p53 activates expression of HIC-1, a new candidate tumor suppressor gene on 17p13.3
-
Wales MM, Biel MA, el Deiry W et al. p53 activates expression of HIC-1, a new candidate tumor suppressor gene on 17p13.3. Nat Med 1995;1:570-577.
-
(1995)
Nat Med
, vol.1
, pp. 570-577
-
-
Wales, M.M.1
Biel, M.A.2
El Deiry, W.3
-
69
-
-
0032530579
-
The expression of the KM1 gene, a tumor metastasis suppressor, is directly activated by p53
-
Mashimo T, Watabe M, Hirota S et al. The expression of the KM1 gene, a tumor metastasis suppressor, is directly activated by p53. Proc Natl Acad Sci USA 1998;95:11307-11311.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 11307-11311
-
-
Mashimo, T.1
Watabe, M.2
Hirota, S.3
-
70
-
-
0026724877
-
Accumulation of p53 tumor suppressor gene protein: An independent marker of prognosis in breast cancers
-
Thor AD, Moore DH II, Edgerton SM et al. Accumulation of p53 tumor suppressor gene protein: an independent marker of prognosis in breast cancers. J Natl Cancer Inst 1992;84:845-855.
-
(1992)
J Natl Cancer Inst
, vol.84
, pp. 845-855
-
-
Thor, A.D.1
Moore II, D.H.2
Edgerton, S.M.3
-
71
-
-
0034972061
-
p53 protein expression and oestrogen and progesterone receptor status in invasive ductal breast carcinomas
-
Ioakim-Liossi A, Karakitsos P, Markopoulos C et al. p53 protein expression and oestrogen and progesterone receptor status in invasive ductal breast carcinomas. Cytopathology 2001;12:197-202.
-
(2001)
Cytopathology
, vol.12
, pp. 197-202
-
-
Ioakim-Liossi, A.1
Karakitsos, P.2
Markopoulos, C.3
-
72
-
-
0009941731
-
Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999
-
Fitzgibbons PL, Page DL, Weaver D et al. Prognostic factors in breast cancer. College of American Pathologists Consensus Statement 1999. Arch Pathol Lab Med 2000;124:966-978.
-
(2000)
Arch Pathol Lab Med
, vol.124
, pp. 966-978
-
-
Fitzgibbons, P.L.1
Page, D.L.2
Weaver, D.3
-
73
-
-
0029665852
-
Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk 2 complex
-
Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk 2 complex. Nature 1996;382:325-331.
-
(1996)
Nature
, vol.382
, pp. 325-331
-
-
Russo, A.A.1
Jeffrey, P.D.2
Patten, A.K.3
-
75
-
-
85047677382
-
Kip1 in osteoblast-like cells during differentiation with parathyroid hormone
-
Kip1 in osteoblast-like cells during differentiation with parathyroid hormone. Endocrinology 1997;138:1995-2004.
-
(1997)
Endocrinology
, vol.138
, pp. 1995-2004
-
-
Onishi, T.1
Hruska, K.2
-
77
-
-
0030002553
-
p27/Kip1 mutation found in breast cancer
-
Spirin KS, Simpson JF, Takeuchi S et al. p27/Kip1 mutation found in breast cancer. Cancer Res 1996;56:2400-2404.
-
(1996)
Cancer Res
, vol.56
, pp. 2400-2404
-
-
Spirin, K.S.1
Simpson, J.F.2
Takeuchi, S.3
-
78
-
-
14444268041
-
Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
-
Esposito V, Baldi A, De Luca A et al. Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res 1997;57:3381-3385.
-
(1997)
Cancer Res
, vol.57
, pp. 3381-3385
-
-
Esposito, V.1
Baldi, A.2
De Luca, A.3
-
79
-
-
0031048236
-
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
-
Loda M, Cukor B, Tam SW et al. Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997;3:231-234.
-
(1997)
Nat Med
, vol.3
, pp. 231-234
-
-
Loda, M.1
Cukor, B.2
Tam, S.W.3
-
81
-
-
0031048716
-
Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
-
Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med 1997;3:222-225.
-
(1997)
Nat Med
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
-
82
-
-
0030947356
-
High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27(kip1) and degree of malignancy in some human breast and colorectal cancers
-
Fredersdorf S, Bums J, Milne AM et al. High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in some human breast and colorectal cancers. Proc Natl Acad Sci USA 1997;94:6380-6385.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6380-6385
-
-
Fredersdorf, S.1
Bums, J.2
Milne, A.M.3
-
83
-
-
0030894787
-
The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinoma
-
Tan P, Cady B, Wanner M et al. The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinoma. Cancer Res 1997;57:1259-1263.
-
(1997)
Cancer Res
, vol.57
, pp. 1259-1263
-
-
Tan, P.1
Cady, B.2
Wanner, M.3
-
84
-
-
0028786916
-
Antiestrogen inhibition of cell cycle progression in breast cancer cells is associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation
-
Watts CK, Brady A, Sarcevic B et al. Antiestrogen inhibition of cell cycle progression in breast cancer cells is associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation. Mol Endocrinol 1995;9:1804-1813.
-
(1995)
Mol Endocrinol
, vol.9
, pp. 1804-1813
-
-
Watts, C.K.1
Brady, A.2
Sarcevic, B.3
-
85
-
-
0036733716
-
Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
-
Signoretti S, Di Marcotullio L, Richardson A et al. Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest 2002;110:633-641.
-
(2002)
J Clin Invest
, vol.110
, pp. 633-641
-
-
Signoretti, S.1
Di Marcotullio, L.2
Richardson, A.3
-
86
-
-
0025613812
-
Linkage of early-onset familial breast cancer to chromosome 17q21
-
Hall JM, Lee MK, Newman B et al. Linkage of early-onset familial breast cancer to chromosome 17q21. Science 1990;250:1684-1689.
-
(1990)
Science
, vol.250
, pp. 1684-1689
-
-
Hall, J.M.1
Lee, M.K.2
Newman, B.3
-
87
-
-
0028113345
-
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
-
Miki Y, Swensen J, Shattuck-Eidens D et al. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 1994;266:66-71.
-
(1994)
Science
, vol.266
, pp. 66-71
-
-
Miki, Y.1
Swensen, J.2
Shattuck-Eidens, D.3
-
88
-
-
0028826709
-
Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence
-
Ford D, Easton DF, Peto J. Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence. Am J Hum Genet 1995;57:1457-1462.
-
(1995)
Am J Hum Genet
, vol.57
, pp. 1457-1462
-
-
Ford, D.1
Easton, D.F.2
Peto, J.3
-
89
-
-
0029794992
-
Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2
-
Roa BB, Boyd AA, Volcik K et al. Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2. Nat Genet 1996;14:185-187.
-
(1996)
Nat Genet
, vol.14
, pp. 185-187
-
-
Roa, B.B.1
Boyd, A.A.2
Volcik, K.3
-
90
-
-
17344365851
-
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
-
The Breast Cancer Linkage Consortium
-
Ford D, Easton DF, Stratton M et al. Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium. Am J Hum Genet 1998;62:676-689.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 676-689
-
-
Ford, D.1
Easton, D.F.2
Stratton, M.3
-
91
-
-
0027433563
-
Genetic linkage analysis in familial breast and ovarian cancer: Results from 214 families
-
The Breast Cancer Linkage Consortium
-
Easton DF, Bishop DT, Ford D et al. Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium. Am J Hum Genet 1993;52:678-701.
-
(1993)
Am J Hum Genet
, vol.52
, pp. 678-701
-
-
Easton, D.F.1
Bishop, D.T.2
Ford, D.3
-
92
-
-
0032441791
-
The genetics of breast cancer susceptibility
-
Rahman N, Stratton MR. The genetics of breast cancer susceptibility. Ann Rev Genet 1998;32:95-121.
-
(1998)
Ann Rev Genet
, vol.32
, pp. 95-121
-
-
Rahman, N.1
Stratton, M.R.2
-
93
-
-
0029898841
-
Molecular modeling of the amino-terminal zinc ring domain of BRCA1
-
Bienstock RJ, Darden T, Wiseman R et al. Molecular modeling of the amino-terminal zinc ring domain of BRCA1. Cancer Res 1996;56:2539-2545.
-
(1996)
Cancer Res
, vol.56
, pp. 2539-2545
-
-
Bienstock, R.J.1
Darden, T.2
Wiseman, R.3
-
94
-
-
0030850047
-
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
-
Scully R, Chen J, Ochs RL et al. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell 1997;90:425-435.
-
(1997)
Cell
, vol.90
, pp. 425-435
-
-
Scully, R.1
Chen, J.2
Ochs, R.L.3
-
95
-
-
0343918505
-
BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer
-
Couch FJ, DeShano ML, Blackwood MA et al. BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer. New Engl J Med 1997;336:1409-1415.
-
(1997)
New Engl J Med
, vol.336
, pp. 1409-1415
-
-
Couch, F.J.1
DeShano, M.L.2
Blackwood, M.A.3
-
96
-
-
8944260900
-
Truncation at conserved terminal regions of BRCAI protein is associated with highly proliferating hereditary breast cancers
-
Sobol H, Stoppa-Lyonnet D, Bressac-de-Paillerets B et al. Truncation at conserved terminal regions of BRCAI protein is associated with highly proliferating hereditary breast cancers. Cancer Res 1996;56:3216-3219.
-
(1996)
Cancer Res
, vol.56
, pp. 3216-3219
-
-
Sobol, H.1
Stoppa-Lyonnet, D.2
Bressac-De-Paillerets, B.3
-
97
-
-
0342940785
-
Pathology of familial breast cancer: Differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases
-
Breast Cancer Linkage Consortium. Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet 1997;349:1505-1510.
-
(1997)
Lancet
, vol.349
, pp. 1505-1510
-
-
-
98
-
-
0034332555
-
Immunophenotypic and pathologic differences between BRCA1 and BRCA2 hereditary breast cancers
-
Phillips KA. Immunophenotypic and pathologic differences between BRCA1 and BRCA2 hereditary breast cancers. J Clin Oncology 2000;18(21 suppl):107S-112S.
-
(2000)
J Clin Oncology
, vol.18
, Issue.21 SUPPL.
-
-
Phillips, K.A.1
-
99
-
-
10744222271
-
MYC is amplified in BRCA1-associated breast cancers
-
Grushko TA, Dignam JJ, Das S et al. MYC is amplified in BRCA1-associated breast cancers. Clin Cancer Res 2004;10:499-507.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 499-507
-
-
Grushko, T.A.1
Dignam, J.J.2
Das, S.3
-
100
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 2003;100:8418-8423.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
-
101
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Dominguez G et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 2000;92:564-569.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
102
-
-
0028006563
-
Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13
-
Wooster R, Neuhausen SL, Mangion J et al. Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 1994;265:2088-2090.
-
(1994)
Science
, vol.265
, pp. 2088-2090
-
-
Wooster, R.1
Neuhausen, S.L.2
Mangion, J.3
-
103
-
-
0006713602
-
Identification of the breast cancer susceptibility gene BRCA2
-
Wooster R, Bignell G, Lancaster J et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995;378:789-792.
-
(1995)
Nature
, vol.378
, pp. 789-792
-
-
Wooster, R.1
Bignell, G.2
Lancaster, J.3
-
104
-
-
0030956589
-
Study of a single BRCA2 mutation with a high carrier frequency in a small population
-
Thorlacius S, Sigurdsson S, Bjamadottir H et al. Study of a single BRCA2 mutation with a high carrier frequency in a small population. Am J Hum Genet 1997;60:1079-1084.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 1079-1084
-
-
Thorlacius, S.1
Sigurdsson, S.2
Bjamadottir, H.3
-
105
-
-
0031018551
-
Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population
-
Friedman LS, Gayther SA, Kurosaki T et al. Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population. Am J Hum Genet 1997;60:313-319.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 313-319
-
-
Friedman, L.S.1
Gayther, S.A.2
Kurosaki, T.3
-
106
-
-
0035931947
-
Gene-expression profiles in hereditary breast cancer
-
Hedenfalk I, Duggan D, Chen Y et al. Gene-expression profiles in hereditary breast cancer. N Engl J Med 2001;344:539-548.
-
(2001)
N Engl J Med
, vol.344
, pp. 539-548
-
-
Hedenfalk, I.1
Duggan, D.2
Chen, Y.3
-
107
-
-
0038501057
-
American Society of Clinical Oncology policy statement update: Genetic testing for cancer susceptibility
-
American Society of Clinical Oncology. American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility. J Clin Oncol 2003;21:2397-2406.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2397-2406
-
-
-
108
-
-
0030893779
-
Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2
-
Cancer Genetics Studies Consortium
-
Burke W, Daly M, Garber J et al. Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium. JAMA 1997;277:997-1003.
-
(1997)
JAMA
, vol.277
, pp. 997-1003
-
-
Burke, W.1
Daly, M.2
Garber, J.3
-
109
-
-
0028910194
-
Loss of heterozygosity and linkage analysis in breast carcinoma: Indication for a putative third susceptibility gene on the short arm of chromosome 8
-
Kerangueven F, Essioux L, Dib A et al. Loss of heterozygosity and linkage analysis in breast carcinoma: indication for a putative third susceptibility gene on the short arm of chromosome 8. Oncogene 1995;10:1023-1026.
-
(1995)
Oncogene
, vol.10
, pp. 1023-1026
-
-
Kerangueven, F.1
Essioux, L.2
Dib, A.3
-
110
-
-
0035168724
-
The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy
-
Mills GB, Lu Y, Fang X et al. The role of genetic abnormalities of PTEN and the phosphatidylinositol 3-kinase pathway in breast and ovarian tumorigenesis, prognosis, and therapy. Semin Oncol 2001;28(suppl 16):125-141.
-
(2001)
Semin Oncol
, vol.28
, Issue.SUPPL. 16
, pp. 125-141
-
-
Mills, G.B.1
Lu, Y.2
Fang, X.3
-
111
-
-
8544247944
-
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease
-
Nelen MR, van Staveren WC, Peeters EA et al. Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. Hum Mol Genet 1997;6:1383-1387.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1383-1387
-
-
Nelen, M.R.1
Van Staveren, W.C.2
Peeters, E.A.3
-
112
-
-
0033601346
-
Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome
-
Bell DW, Varley JM, Szydlo TE et al. Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome. Science 1999;286:2528-2531.
-
(1999)
Science
, vol.286
, pp. 2528-2531
-
-
Bell, D.W.1
Varley, J.M.2
Szydlo, T.E.3
-
113
-
-
18444379055
-
A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer
-
Vahteristo P, Bartkova J, Eerola H et al. A CHEK2 genetic variant contributing to a substantial fraction of familial breast cancer. Am J Hum Genet 2002;71:432-438.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 432-438
-
-
Vahteristo, P.1
Bartkova, J.2
Eerola, H.3
-
114
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003;3:155-168.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
115
-
-
0034679076
-
Cancer risk and the ATM gene: A continuing debate
-
Khanna KK. Cancer risk and the ATM gene: a continuing debate. J Natl Cancer Inst 2000;92:795-802.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 795-802
-
-
Khanna, K.K.1
-
116
-
-
0023106062
-
Human retinoblastoma susceptibility gene: Cloning, identification, and sequence
-
Lee WH, Bookstein R, Hong F et al. Human retinoblastoma susceptibility gene: cloning, identification, and sequence. Science 1987;235:1394-1399.
-
(1987)
Science
, vol.235
, pp. 1394-1399
-
-
Lee, W.H.1
Bookstein, R.2
Hong, F.3
-
117
-
-
0026721588
-
Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas
-
Andersen TI, Gaustad A, Ottestad L et al. Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas. Genes Chromosomes Cancer 1992;4:113-121.
-
(1992)
Genes Chromosomes Cancer
, vol.4
, pp. 113-121
-
-
Andersen, T.I.1
Gaustad, A.2
Ottestad, L.3
-
118
-
-
0034469507
-
Gene therapy for carcinoma of the breast: Therapeutic genetic correction strategies
-
Obermiller PS, Tait DL, Holt JT. Gene therapy for carcinoma of the breast: therapeutic genetic correction strategies. Breast Cancer Res 2000;2:28-31.
-
(2000)
Breast Cancer Res
, vol.2
, pp. 28-31
-
-
Obermiller, P.S.1
Tait, D.L.2
Holt, J.T.3
-
119
-
-
0033526357
-
Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer
-
Swisher SG, Roth JA, Nemunaitis J et al. Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. J Natl Cancer Inst 1999;91:763-771.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 763-771
-
-
Swisher, S.G.1
Roth, J.A.2
Nemunaitis, J.3
-
120
-
-
0037627875
-
Why did p53 gene therapy fail in ovarian cancer?
-
Zeimet AG, Marth C. Why did p53 gene therapy fail in ovarian cancer? Lancet Oncol 2003;4:415-422.
-
(2003)
Lancet Oncol
, vol.4
, pp. 415-422
-
-
Zeimet, A.G.1
Marth, C.2
-
121
-
-
0032790963
-
Ovarian cancer BRCA1 gene therapy: Phase I and II trial differences in immune response and vector stability
-
Tait DL, Obermiller PS, Hatmaker AR et al. Ovarian cancer BRCA1 gene therapy: Phase I and II trial differences in immune response and vector stability. Clin Cancer Res 1999;5:1708-1714.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 1708-1714
-
-
Tait, D.L.1
Obermiller, P.S.2
Hatmaker, A.R.3
-
123
-
-
0035879090
-
Cationic liposome-mediated EIA gene transfer to human breast and ovarian cancer cells and its biologic effects: A phase I clinical trial
-
Hortobagyi GN, Ueno NT, Xia W et al. Cationic liposome-mediated EIA gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial. J Clin Oncol 2001;19:3422-3433.
-
(2001)
J Clin Oncol
, vol.19
, pp. 3422-3433
-
-
Hortobagyi, G.N.1
Ueno, N.T.2
Xia, W.3
-
124
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumours. Nature 2000;406:747-752.
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
125
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001;98:10869-10874.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
126
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver MJ, He YD, van't Veer LJ et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002;347:1999-2009.
-
(2002)
N Engl J Med
, vol.347
, pp. 1999-2009
-
-
Van De Vijver, M.J.1
He, Y.D.2
Van't Veer, L.J.3
-
128
-
-
0037387176
-
Use of serological proteomic methods to find biomarkers associated with breast cancer
-
Rui Z, Jian-Guo J, Yuan-Peng T et al. Use of serological proteomic methods to find biomarkers associated with breast cancer. Proteomics 2003;3:433-439.
-
(2003)
Proteomics
, vol.3
, pp. 433-439
-
-
Rui, Z.1
Jian-Guo, J.2
Yuan-Peng, T.3
-
129
-
-
0037485656
-
Proteomic characterization of nipple aspirate fluid: Identification of potential biomarkers of breast cancer
-
Vamum SM, Covington CC, Woodbury RL et al. Proteomic characterization of nipple aspirate fluid: identification of potential biomarkers of breast cancer. Breast Cancer Res Treat 2003;80:87-97.
-
(2003)
Breast Cancer Res Treat
, vol.80
, pp. 87-97
-
-
Vamum, S.M.1
Covington, C.C.2
Woodbury, R.L.3
-
131
-
-
0041301731
-
Emerging science: Prospective validation of gene expression profiling-based prediction of complete pathologic response to neoadjuvant paclitaxel/FAC chemotherapy in breast cancer
-
Pusztai L, Ayers M, Simmans FW et al. Emerging science: prospective validation of gene expression profiling-based prediction of complete pathologic response to neoadjuvant paclitaxel/FAC chemotherapy in breast cancer. Proc Am Soc Clin Oncol 2003;22:1A.
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
-
-
Pusztai, L.1
Ayers, M.2
Simmans, F.W.3
-
132
-
-
0042125511
-
Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer
-
Chang JC, Wooten EC, Tsimelzon A et al. Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. Lancet 2003;362:362-369.
-
(2003)
Lancet
, vol.362
, pp. 362-369
-
-
Chang, J.C.1
Wooten, E.C.2
Tsimelzon, A.3
-
133
-
-
17344371740
-
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
-
Pinkel D, Segraves R, Sudar D et al. High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays. Nat Genet 1998;20:207-211.
-
(1998)
Nat Genet
, vol.20
, pp. 207-211
-
-
Pinkel, D.1
Segraves, R.2
Sudar, D.3
-
134
-
-
13144267754
-
Positional cloning of ZNF217 and NABC1: Genes amplified at 20q13.2 and overexpressed in breast carcinoma
-
Collins C, Rommens JM, Kowbel D et al. Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma. Proc Natl Acad Sci USA 1998;95:8703-8708.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8703-8708
-
-
Collins, C.1
Rommens, J.M.2
Kowbel, D.3
-
135
-
-
0034129516
-
Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
-
Albertson DG, Ylstra B, Segraves R et al. Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nat Genet 2000;25:144-146.
-
(2000)
Nat Genet
, vol.25
, pp. 144-146
-
-
Albertson, D.G.1
Ylstra, B.2
Segraves, R.3
-
138
-
-
3543012851
-
Drug metabolism polymorphisms and outcome in node-positive breast cancer patients: Differential impact of glutathione-S-transferase subtypes
-
DeMichele A, Aplenc R, Botbyl J et al. Drug metabolism polymorphisms and outcome in node-positive breast cancer patients: differential impact of glutathione-S-transferase subtypes. Breast Cancer Res Treat 2003;82(suppl 1):S14.
-
(2003)
Breast Cancer Res Treat
, vol.82
, Issue.SUPPL. 1
-
-
DeMichele, A.1
Aplenc, R.2
Botbyl, J.3
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