-
1
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, McGuire WL. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 1987; 235: 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
3
-
-
0025211332
-
Expression of epidermal growth factor receptor in breast carcinoma
-
Lewis S, Locker A, Todd JH, et al. Expression of epidermal growth factor receptor in breast carcinoma. J Clin Pathol 1990; 43: 385-389.
-
(1990)
J. Clin. Pathol.
, vol.43
, pp. 385-389
-
-
Lewis, S.1
Locker, A.2
Todd, J.H.3
-
4
-
-
0031759864
-
The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy
-
Ross JS, Fletcher JA. The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy. Stem Cells 1998; 16: 413-418.
-
(1998)
Stem Cells
, vol.16
, pp. 413-418
-
-
Ross, J.S.1
Fletcher, J.A.2
-
6
-
-
0035122438
-
The value of the human epidermal growth factor receptor-2 (HER2) as a prognostic marker
-
Cooke T, Reeves J, Lannigan A, Stanton P. The value of the human epidermal growth factor receptor-2 (HER2) as a prognostic marker. Eur J Cancer 2001; 37(Suppl 1): S3-S10.
-
(2001)
Eur. J. Cancer
, vol.37
, Issue.SUPPL. 1
-
-
Cooke, T.1
Reeves, J.2
Lannigan, A.3
Stanton, P.4
-
8
-
-
0021273420
-
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
-
Ullrich A, Coussens L, Hayflick JS, et al. Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 1984; 309: 418-425.
-
(1984)
Nature
, vol.309
, pp. 418-425
-
-
Ullrich, A.1
Coussens, L.2
Hayflick, J.S.3
-
9
-
-
0022399581
-
Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
-
Coussens L, Yang-Feng TL, Liao YC, et al. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. Science 1985; 230: 1132-1139.
-
(1985)
Science
, vol.230
, pp. 1132-1139
-
-
Coussens, L.1
Yang-Feng, T.L.2
Liao, Y.C.3
-
10
-
-
0024326947
-
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: Evidence for overexpression in a subset of human mammary tumours
-
Kraus MH, Issing W, Miki T, Popescu NC, Aaronson SA. Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumours. Proc Natl Acad Sci USA 1989; 86: 9193-9197.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 9193-9197
-
-
Kraus, M.H.1
Issing, W.2
Miki, T.3
Popescu, N.C.4
Aaronson, S.A.5
-
11
-
-
0027447680
-
Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family
-
Plowman GD, Culouscou JM, Whitney GS, et al. Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family. Proc Natl Acad Sci U S A 1993; 90: 1746-1750.
-
(1993)
Proc. Natl. Acad. Sci. U S A
, vol.90
, pp. 1746-1750
-
-
Plowman, G.D.1
Culouscou, J.M.2
Whitney, G.S.3
-
12
-
-
0032850677
-
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
-
Cobleigh MA, Vogel CL, Tripathy D, et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 1999; 17: 2639-2648.
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2639-2648
-
-
Cobleigh, M.A.1
Vogel, C.L.2
Tripathy, D.3
-
13
-
-
0032913299
-
The HER-2/neu story: From oncogene through prognostic marker to therapeutic strategy determinant and monoclonal therapy
-
Mehigan BJ, Kerin MJ. The HER-2/neu story: from oncogene through prognostic marker to therapeutic strategy determinant and monoclonal therapy. Eur J Surg Oncol 1999; 25: 111-112.
-
(1999)
Eur. J. Surg. Oncol.
, vol.25
, pp. 111-112
-
-
Mehigan, B.J.1
Kerin, M.J.2
-
14
-
-
0032841436
-
Therapy of metastatic breast cancer with humanized antibodies against the HER2 receptor protein
-
Schaller G, Bangeman N, Becker C, Buhler H, Opri F, Weitzel HK. Therapy of metastatic breast cancer with humanized antibodies against the HER2 receptor protein. J Cancer Res Clin Oncol 1999; 125: 520-524.
-
(1999)
J. Cancer Res. Clin. Oncol.
, vol.125
, pp. 520-524
-
-
Schaller, G.1
Bangeman, N.2
Becker, C.3
Buhler, H.4
Opri, F.5
Weitzel, H.K.6
-
15
-
-
19244366949
-
Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin
-
Baselga J, Pfister D, Cooper MR, et al. Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin. J Clin Oncol 2000; 18: 904-914.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 904-914
-
-
Baselga, J.1
Pfister, D.2
Cooper, M.R.3
-
16
-
-
0034068319
-
Antitumour effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor
-
Ciardiello F, Caputo R, Bianco R, et al. Antitumour effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor. Clin Cancer Res 2000; 6: 2053-2063.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
-
17
-
-
0036139884
-
Receptor tyrosine kinases as targets for anticancer drugs
-
Zwick E, Bange J, Ullrich A. Receptor tyrosine kinases as targets for anticancer drugs. Trends Mol Med 2002; 8: 17-21.
-
(2002)
Trends Mol. Med.
, vol.8
, pp. 17-21
-
-
Zwick, E.1
Bange, J.2
Ullrich, A.3
-
18
-
-
0031936410
-
Specificity within the EGF family/ErbB receptor family signaling network
-
Riese DJ 2nd, Stern DF. Specificity within the EGF family/ErbB receptor family signaling network. Bioessays 1998; 20: 41-48.
-
(1998)
Bioessays
, vol.20
, pp. 41-48
-
-
Riese D.J. II1
Stern, D.F.2
-
19
-
-
0034600849
-
The ErbB signaling network: Receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, Hynes NE. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000; 19: 3159-3167.
-
(2000)
EMBO J.
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
Hynes, N.E.4
-
21
-
-
0034773992
-
The EGFR family and its ligands in human cancer: Signalling mechanisms and therapeutic opportunities
-
Yarden Y. The EGFR family and its ligands in human cancer: signalling mechanisms and therapeutic opportunities. Eur J Cancer 2001; 37: S3-S8.
-
(2001)
Eur. J. Cancer
, vol.37
-
-
Yarden, Y.1
-
22
-
-
0033608993
-
The erbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors
-
Klapper LN, Glathe S, Vaisman N, et al. The erbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors. Proc Natl Acad Sci USA 1999; 96: 4995-5000.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4995-5000
-
-
Klapper, L.N.1
Glathe, S.2
Vaisman, N.3
-
23
-
-
0028168569
-
Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity
-
Guy PM, Platko JV, Cantley LC, Cerione RA, Carraway KL. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc Natl Acad Sci U S A 1994; 91: 8132-8136.
-
(1994)
Proc. Natl. Acad. Sci. U S A
, vol.91
, pp. 8132-8136
-
-
Guy, P.M.1
Platko, J.V.2
Cantley, L.C.3
Cerione, R.A.4
Carraway, K.L.5
-
24
-
-
0034959016
-
The type 1 growth factor receptors and their ligands considered as a complex system
-
Gullick WJ. The type 1 growth factor receptors and their ligands considered as a complex system. Endocrine-Related Cancer 2001; 8: 75-82.
-
(2001)
Endocrine-Related Cancer
, vol.8
, pp. 75-82
-
-
Gullick, W.J.1
-
25
-
-
0035868342
-
Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumour suppressor PTEN
-
Pianetti S, Arsura M, Romieu-Mourez R, Coffey RJ, Sonenshein GE. Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumour suppressor PTEN. Oncogene 2001; 20: 1287-1299.
-
(2001)
Oncogene
, vol.20
, pp. 1287-1299
-
-
Pianetti, S.1
Arsura, M.2
Romieu-Mourez, R.3
Coffey, R.J.4
Sonenshein, G.E.5
-
26
-
-
0030795612
-
The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
-
Alroy I, Yarden Y. The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions. FEBS Lett 1997; 410: 83-86.
-
(1997)
FEBS Lett.
, vol.410
, pp. 83-86
-
-
Alroy, I.1
Yarden, Y.2
-
27
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta D, Beerli RR, Daly JM, Hynes NE. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 1997; 16: 1647-1655.
-
(1997)
EMBO J.
, vol.16
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
28
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
Prenzel N, Fischer OM, Streit S, Hart S, Ullrich A. The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocrine-Related Cancer 2001; 8: 11-21.
-
(2001)
Endocrine-Related Cancer
, vol.8
, pp. 11-21
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
Hart, S.4
Ullrich, A.5
-
29
-
-
0033959896
-
A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling
-
Rodrigues GA, Falasca M, Zhang Z, Ong SH, Schlessinger J. A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling. Mol Cell Biol 2000; 20: 1448-1459.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 1448-1459
-
-
Rodrigues, G.A.1
Falasca, M.2
Zhang, Z.3
Ong, S.H.4
Schlessinger, J.5
-
30
-
-
0033607633
-
Phosphorylation and regulation of Raf by Akt (protein kinase B)
-
Zimmermann S, Moelling K. Phosphorylation and regulation of Raf by Akt (protein kinase B). Science 1999; 286: 1741-1744.
-
(1999)
Science
, vol.286
, pp. 1741-1744
-
-
Zimmermann, S.1
Moelling, K.2
-
31
-
-
0033747558
-
Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay
-
Pawlowski V, Revillion F, Hebbar M, Hornez L, Peyrat JP. Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay. Clin Cancer Res 2000; 6: 4217-4225.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 4217-4225
-
-
Pawlowski, V.1
Revillion, F.2
Hebbar, M.3
Hornez, L.4
Peyrat, J.P.5
-
32
-
-
0028089205
-
Localization of EGF receptors in frozen tissue sections by antibody and biotinylated EGF-based techniques
-
Reeves JR, Cooke TG, Fenton-Lee D, et al. Localization of EGF receptors in frozen tissue sections by antibody and biotinylated EGF-based techniques. J Histochem Cytochem 1994; 42: 307-314.
-
(1994)
J. Histochem. Cytochem.
, vol.42
, pp. 307-314
-
-
Reeves, J.R.1
Cooke, T.G.2
Fenton-Lee, D.3
-
33
-
-
0029742067
-
Quantitative estimation of epidermal growth factor receptor and c-erbB-2 in human breast cancer
-
Robertson KW, Reeves JR, Smith G, et al. Quantitative estimation of epidermal growth factor receptor and c-erbB-2 in human breast cancer. Cancer Res 1996; 56: 3823-3830.
-
(1996)
Cancer Res.
, vol.56
, pp. 3823-3830
-
-
Robertson, K.W.1
Reeves, J.R.2
Smith, G.3
-
34
-
-
0035162262
-
Evaluating HER2 amplification and overexpression in breast cancer
-
Bartlett JMS, Going JJ, Mallon EA, et al. Evaluating HER2 amplification and overexpression in breast cancer. J Pathol 2001; 195: 422-428.
-
(2001)
J. Pathol.
, vol.195
, pp. 422-428
-
-
Bartlett, J.M.S.1
Going, J.J.2
Mallon, E.A.3
-
36
-
-
0031730476
-
Expression of c-erbB3 protein in primary breast carcinomas
-
Naidu R, Yadav M, Nair S, Kutty MK. Expression of c-erbB3 protein in primary breast carcinomas. Br J Cancer 1998; 78: 1385-1390.
-
(1998)
Br. J. Cancer
, vol.78
, pp. 1385-1390
-
-
Naidu, R.1
Yadav, M.2
Nair, S.3
Kutty, M.K.4
-
37
-
-
0027076771
-
Expression of the ERBB3 gene product in breast cancer
-
Lemoine NR, Barnes DM, Hollywood DP, et al. Expression of the ERBB3 gene product in breast cancer. Br J Cancer 1992; 66: 1116-1121.
-
(1992)
Br. J. Cancer
, vol.66
, pp. 1116-1121
-
-
Lemoine, N.R.1
Barnes, D.M.2
Hollywood, D.P.3
-
38
-
-
0029665946
-
C-erbB-3 in human breast carcinoma: Expression and relation to prognosis and established prognostic indicators
-
Travis A, Pinder SE, Robertson JF, et al. C-erbB-3 in human breast carcinoma: expression and relation to prognosis and established prognostic indicators. Br J Cancer 1996; 74: 229-233.
-
(1996)
Br. J. Cancer
, vol.74
, pp. 229-233
-
-
Travis, A.1
Pinder, S.E.2
Robertson, J.F.3
-
39
-
-
0032532214
-
c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer
-
Knowlden JM, Gee JM, Seery LT, et al. c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer. Oncogene 1998; 17: 1949-1957.
-
(1998)
Oncogene
, vol.17
, pp. 1949-1957
-
-
Knowlden, J.M.1
Gee, J.M.2
Seery, L.T.3
-
40
-
-
0028169757
-
c-erbB-3 protein expression in human breast cancer: Comparison with other tumour variables and survival
-
Quinn CM, Ostrowski JL, Lane SA, Loney DP, Teasdale J, Benson FA. c-erbB-3 protein expression in human breast cancer: comparison with other tumour variables and survival. Histopathology 1994; 25: 247-252.
-
(1994)
Histopathology
, vol.25
, pp. 247-252
-
-
Quinn, C.M.1
Ostrowski, J.L.2
Lane, S.A.3
Loney, D.P.4
Teasdale, J.5
Benson, F.A.6
-
41
-
-
0035360262
-
A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4
-
Lee H, Akita RW, Sliwkowski MX, Maihle NJ. A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4. Cancer Res 2001; 61: 4467-4473.
-
(2001)
Cancer Res.
, vol.61
, pp. 4467-4473
-
-
Lee, H.1
Akita, R.W.2
Sliwkowski, M.X.3
Maihle, N.J.4
-
42
-
-
0025254421
-
Relationship between epidermal growth factor receptor status and various prognostic factors in human breast cancer
-
Toi M, Nakamura T, Mukaida H, et al. Relationship between epidermal growth factor receptor status and various prognostic factors in human breast cancer. Cancer 1990; 65: 1980-1984.
-
(1990)
Cancer
, vol.65
, pp. 1980-1984
-
-
Toi, M.1
Nakamura, T.2
Mukaida, H.3
-
43
-
-
0032413307
-
The type 1 growth factor receptor family: New ligands and receptors and their role in breast cancer
-
Gullick WJ, Srinivasan R. The type 1 growth factor receptor family: new ligands and receptors and their role in breast cancer. Breast Cancer Res Treat 1998; 52: 43-53.
-
(1998)
Breast Cancer Res. Treat.
, vol.52
, pp. 43-53
-
-
Gullick, W.J.1
Srinivasan, R.2
-
44
-
-
0034638920
-
HER2/neu: Mechanisms of dimerization/oligomerization
-
Brennan PJ, Kumogai T, Berezov A, Murali R, Greene MI. HER2/neu: mechanisms of dimerization/oligomerization. Oncogene 2000; 19: 6093-6101.
-
(2000)
Oncogene
, vol.19
, pp. 6093-6101
-
-
Brennan, P.J.1
Kumogai, T.2
Berezov, A.3
Murali, R.4
Greene, M.I.5
-
45
-
-
0031827634
-
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types
-
Srinivasan R, Poulsom R, Hurst HC, Gullick WJ. Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types. J Pathol 1998; 185: 236-245.
-
(1998)
J. Pathol.
, vol.185
, pp. 236-245
-
-
Srinivasan, R.1
Poulsom, R.2
Hurst, H.C.3
Gullick, W.J.4
-
46
-
-
0034053352
-
C-erbb-4 protein expression in human breast cancer
-
Kew TY, Bell JA, Pinder SE, et al. C-erbb-4 protein expression in human breast cancer. Br J Cancer 2000; 82: 1163-1170.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 1163-1170
-
-
Kew, T.Y.1
Bell, J.A.2
Pinder, S.E.3
-
47
-
-
0034918674
-
Estrogen receptor-alpha and C-ERBB-4 expression in breast carcinomas
-
Suo Z, Berner HS, Risberg B, Karlsson MG, Nesland JM. Estrogen receptor-alpha and C-ERBB-4 expression in breast carcinomas. Virchows Arch 2001; 439: 62-69.
-
(2001)
Virchows Arch.
, vol.439
, pp. 62-69
-
-
Suo, Z.1
Berner, H.S.2
Risberg, B.3
Karlsson, M.G.4
Nesland, J.M.5
-
48
-
-
0032570061
-
Amplification of erbB-4 oncogene occurs less frequently than that of erbB-2 in primary human breast cancer
-
Vogt U, Bielawski K, Schlotter CM, Bosse U, Falkiewicz B, Podhajska AJ. Amplification of erbB-4 oncogene occurs less frequently than that of erbB-2 in primary human breast cancer. Gene 1998; 223: 375-380.
-
(1998)
Gene
, vol.223
, pp. 375-380
-
-
Vogt, U.1
Bielawski, K.2
Schlotter, C.M.3
Bosse, U.4
Falkiewicz, B.5
Podhajska, A.J.6
-
49
-
-
0034708598
-
A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis
-
Kainulainen V, Sundvall M, Maatta JA, Santiestevan E, Klagsbrun M, Elenius K. A natural ErbB4 isoform that does not activate phosphoinositide 3-kinase mediates proliferation but not survival or chemotaxis. J Biol Chem 2000; 275: 8641-8649.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8641-8649
-
-
Kainulainen, V.1
Sundvall, M.2
Maatta, J.A.3
Santiestevan, E.4
Klagsbrun, M.5
Elenius, K.6
-
50
-
-
0027976892
-
c-erbB-3 and c-erbB-2 protein expression in node-negative breast carcinoma - An immunocytochemical study
-
Gasparini G, Gullick WJ, Maluta S, et al. c-erbB-3 and c-erbB-2 protein expression in node-negative breast carcinoma - an immunocytochemical study. Eur J Cancer 1994; 30A: 16-22.
-
(1994)
Eur. J. Cancer
, vol.30 A
, pp. 16-22
-
-
Gasparini, G.1
Gullick, W.J.2
Maluta, S.3
-
51
-
-
0029053716
-
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas
-
Alimandi M, Romano A, Curia MC, et al. Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene 1995; 10: 1813-1821.
-
(1995)
Oncogene
, vol.10
, pp. 1813-1821
-
-
Alimandi, M.1
Romano, A.2
Curia, M.C.3
-
52
-
-
0029824114
-
Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification
-
Ram TG, Ethier SP. Phosphatidylinositol 3-kinase recruitment by p185erbB-2 and erbB-3 is potently induced by neu differentiation factor/heregulin during mitogenesis and is constitutively elevated in growth factor-independent breast carcinoma cells with c-erbB-2 gene amplification. Cell Growth Differ 1996; 7: 551-561.
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 551-561
-
-
Ram, T.G.1
Ethier, S.P.2
-
53
-
-
0033561296
-
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 is involved in the induction of mammary tumours in transgenic mice: Implications for human breast cancer
-
Siegel PM, Ryan ED, Cardiff RD, Muller WJ. Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 is involved in the induction of mammary tumours in transgenic mice: implications for human breast cancer. EMBO J 1999; 18: 2149-2164.
-
(1999)
EMBO J.
, vol.18
, pp. 2149-2164
-
-
Siegel, P.M.1
Ryan, E.D.2
Cardiff, R.D.3
Muller, W.J.4
-
54
-
-
0034202884
-
Morphogenetic and proliferative responses to heregulin of mammary epithelial cells in vitro are dependent on HER2 and HER3 and differ from the responses to HER2 homodimerisation or hepatocyte growth factor
-
Baeckstrom D, Alford D, Taylor-Papadimitriou J. Morphogenetic and proliferative responses to heregulin of mammary epithelial cells in vitro are dependent on HER2 and HER3 and differ from the responses to HER2 homodimerisation or hepatocyte growth factor. Int J Oncol 2000; 16: 1081-1090.
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 1081-1090
-
-
Baeckstrom, D.1
Alford, D.2
Taylor-Papadimitriou, J.3
-
55
-
-
0033903187
-
Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines
-
deFazio A, Chiew YE, Sini RL, Janes PW, Sutherland RL. Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines. Int J Cancer 2000; 87: 487-498.
-
(2000)
Int. J. Cancer
, vol.87
, pp. 487-498
-
-
deFazio, A.1
Chiew, Y.E.2
Sini, R.L.3
Janes, P.W.4
Sutherland, R.L.5
-
56
-
-
0033886824
-
Molecular mechanism of a cross-talk between oestrogen and growth factor signalling pathways
-
Kato S, Masuhiro Y, Watanabe M, et al. Molecular mechanism of a cross-talk between oestrogen and growth factor signalling pathways. Genes Cells 2000; 5: 593-601.
-
(2000)
Genes Cells
, vol.5
, pp. 593-601
-
-
Kato, S.1
Masuhiro, Y.2
Watanabe, M.3
-
57
-
-
0034899503
-
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells
-
Oh AS, Lorant LA, Holloway JN, Miller DL, Kern FG, El-Ashry D. Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells. Mol Endocrinol 2001; 15: 1344-1359.
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 1344-1359
-
-
Oh, A.S.1
Lorant, L.A.2
Holloway, J.N.3
Miller, D.L.4
Kern, F.G.5
El-Ashry, D.6
-
58
-
-
0035881568
-
Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K
-
Sun M, Paciga JE, Feldman RI, et al. Phosphatidylinositol-3-OH kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K. Cancer Res 2001; 61: 5985-5991.
-
(2001)
Cancer Res.
, vol.61
, pp. 5985-5991
-
-
Sun, M.1
Paciga, J.E.2
Feldman, R.I.3
-
59
-
-
0035971181
-
Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: A new model for anti-estrogen resistance
-
Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H. Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance. J Biol Chem 2001; 276: 9817-9824.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9817-9824
-
-
Campbell, R.A.1
Bhat-Nakshatri, P.2
Patel, N.M.3
Constantinidou, D.4
Ali, S.5
Nakshatri, H.6
-
60
-
-
0034790009
-
Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer
-
Nicholson RI, Hutcheson IR, Harper ME, et al. Modulation of epidermal growth factor receptor in endocrine-resistant, oestrogen receptor-positive breast cancer. Endocrine-Related Cancer 2001; 8: 175-182.
-
(2001)
Endocrine-Related Cancer
, vol.8
, pp. 175-182
-
-
Nicholson, R.I.1
Hutcheson, I.R.2
Harper, M.E.3
-
61
-
-
0034794636
-
Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer
-
Dowsett M. Overexpression of HER-2 as a resistance mechanism to hormonal therapy for breast cancer. Endocrine-Related Cancer 2001; 8: 191-195.
-
(2001)
Endocrine-Related Cancer
, vol.8
, pp. 191-195
-
-
Dowsett, M.1
-
62
-
-
0034078206
-
Regulation of estrogen receptor-alpha gene expression by epidermal growth factor
-
Stoica A, Saceda M, Doraiswamy VL, Coleman C, Martin MB. Regulation of estrogen receptor-alpha gene expression by epidermal growth factor. J Endocrinol 2000; 165: 371-378.
-
(2000)
J. Endocrinol.
, vol.165
, pp. 371-378
-
-
Stoica, A.1
Saceda, M.2
Doraiswamy, V.L.3
Coleman, C.4
Martin, M.B.5
-
63
-
-
0028046570
-
Oestrogen and epidermal growth factor down-regulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms
-
Antoniotti S, Taverna D, Maggiora P, Sapei ML, Hynes NE, De Bortoli M. Oestrogen and epidermal growth factor down-regulate erbB-2 oncogene protein expression in breast cancer cells by different mechanisms. Br J Cancer 1994; 70: 1095-1101.
-
(1994)
Br. J. Cancer
, vol.70
, pp. 1095-1101
-
-
Antoniotti, S.1
Taverna, D.2
Maggiora, P.3
Sapei, M.L.4
Hynes, N.E.5
De Bortoli, M.6
-
64
-
-
0034719406
-
Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer
-
Newman SP, Bates NP, Vernimmen D, Parker MG, Hurst HC. Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer. Oncogene 2000; 19: 490-497.
-
(2000)
Oncogene
, vol.19
, pp. 490-497
-
-
Newman, S.P.1
Bates, N.P.2
Vernimmen, D.3
Parker, M.G.4
Hurst, H.C.5
-
65
-
-
0034642578
-
AP-2 transcription factor in the regulation of ERBB2 gene transcription by oestrogen
-
Perissi V, Menini N, Cottone E, et al. AP-2 transcription factor in the regulation of ERBB2 gene transcription by oestrogen. Oncogene 2000; 19: 280-288.
-
(2000)
Oncogene
, vol.19
, pp. 280-288
-
-
Perissi, V.1
Menini, N.2
Cottone, E.3
-
66
-
-
0035884620
-
Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a phase III randomized trial
-
Ellis MJ, Coop A, Singh B, et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. J Clin Oncol 2001; 19: 3808-3816.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 3808-3816
-
-
Ellis, M.J.1
Coop, A.2
Singh, B.3
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