BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II)

Cancer Research

Volumn 58, Issue 6, 1998, Pages 1120-1123

  Husain, Amreen ^a   He, Guoshun ^a   Venkatraman, Ennapadam S ^a   Spriggs, David R ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CISPLATIN; GENE PRODUCT;

APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER RESISTANCE; CANCER SUSCEPTIBILITY; CELL CYCLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FEMALE; HUMAN; HUMAN CELL; ONCOGENE; OVARY CARCINOMA; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

BREAST NEOPLASMS; CISPLATIN; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HUMANS; OVARIAN NEOPLASMS; RNA, MESSENGER; RNA, NEOPLASM; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0032521537     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., Bell, R., Rosenthal, J., Hussey, C., Thanh, T., McClure, M., Frye, C., Hattier, T., Phelps, R., Haugen-Shrano, A., Katcher, H., Yakumo, K., Gholami, Z., Shaffer, D., Stone, S., Bayer, S., Wray, C., Bogden, R., Dayananth, P., Ward, J., Tonin, P., Narod, S., Bristow, P. K., Norris, F. H., Helvering, L., Morrison, P., Rosteck, P., Lai, M., Barrett, J. C., Lewis, C., Neuhasen, S., Canon-Albright, L., Galdgar, D., Wiseman, R., Kamb, A., and Skolnick, M. H. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science (Washington DC), 266: 66-71, 1994.
2. Takahashi, H., Behbakht, K., McGovern, P. E., Chiu, H., Couch, F. J., Weber, B. L., Friedman, L. S., King, M., Furusato, M., Livolsi, V. A., Menzin, A. W., Liu, P. C., Benjamin, I., Morgan, M. A., King, S. A., Rebane, B. A., Cardonick, A., Mikuta, J. J., Rubin, S. C., and Boyd, J. Mutation analysis of the BRCA1 gene in ovarian cancers. Cancer Res., 55: 2998-3002, 1995.
3. Scully, R., Chen, J., Plug, A., Xiao, Y., Weaver, D., Feunteun, J., Ashley, T., and Livingston, D. M. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell, 88: 265-275, 1997.
4. Baumann, P. Benson, F. E., and West, S. C. Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro. Cell, 87: 757-766, 1996.
5. Eastman, A. Activation of programmed cell death by anti-cancer agents: CDDP as a model system. Cancer Cells (Cold Spring Harbor), 2: 275-280, 1990.
6. 3H]thymidine incorporation assay. J. Immunol. Methods, 170: 211-224, 1994.
7. Schwartz, G. K., Farsi, K., Maslak, P., and Spriggs, D. R. Potentiation of apoptosis by flavopiridol in mitomycin-C-treated gastric and breast cancer cells. Clin. Cancer Res., 3: 1467-1472, 1997.
8. Husain, A., Yan, X. J., Resales, N., Aghajanian, C., Schwartz, G. K., and Spriggs, D. R. UCN-01 in ovary cancer cells: effective as a single agent and in combination with cis-diamminedichloroplatinum(II) independent of p53 status. Clin. Cancer Res., 3: 2089-2097, 1997.
9. Vaughn, J. P., Davis, P. L., Jarboe, M. D., Huper, G., Evans, A. C., Wiseman, R. W., Berchuck, A., Iglehart, J. D., Futreal, P. A., and Marks, J. R. BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells. Cell Growth Differ., 7: 711-715, 1996.
10. Johnson, S. W., Swiggard, P. A., Handel, L. M., Brennan, J. M., Godwin, A. K., Ozols, R. F., and Hamilton, T. C. Relationship between platinum-DNA adduct formation and removal and CDDP cytotoxicity in CDDP-sensitive and -resistant human ovarian cancer cells. Cancer Res., 54: 5911-5916, 1994.
11. Richon, V. M., Schulte, N., and Eastman, A. Multiple mechanisms of resistance to cis-diamminedichloroplatinum in murine leukemia L1210 cells. Cancer Res., 47: 2056-2060, 1987.
12. Sheibani, N., Jennerwein, M. M., and Eastman, A. DNA repair in cells sensitive and resistant to cis-diamminedichloroplatinum(II): host cell reactivation of damaged plasmid DNA. Biochemistry, 28: 3120-3124, 1989.
13. Dabholkar, M., Bostick-Bruton, F., Weber, C., Bohr, V. A., Egwuagu, C., and Reed, E. ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients. J. Natl. Cancer Inst., 84: 1512-1517, 1992.
14. Rubin, S. C., Benjamin, I., Behbakht, K., Takahashi, H., Morgan, M. A., Livolsi, V. A., Berchuck, A., Muto, M. G., Garber, J. E., Weber, B. L., Lynch, H. T., and Boyd, J. Clinical and pathological features of ovarian cancer in women with germ-line mutations of BRCA1. N. Engl. J. Med., 335: 1413-1416, 1996.