Landscaping the cancer terrain

Science

Volumn 280, Issue 5366, 1998, Pages 1036-1037

  Kinzler, Kenneth W ^a   Vogelstein, Bert ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MUTAGENIC AGENT;

ADENOMATOUS POLYP; ARTICLE; CANCER GROWTH; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL DEATH; GENE ACTIVATION; HUMAN; MALIGNANT NEOPLASTIC DISEASE; PEUTZ JEGHERS SYNDROME; POLYPOSIS; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; ULCERATIVE COLITIS;

CELL DIVISION; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; EPITHELIAL CELLS; GENES, TUMOR SUPPRESSOR; GENETIC PREDISPOSITION TO DISEASE; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; INTESTINAL POLYPS; MUTATION; NEOPLASMS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-TYROSINE-PHOSPHATASE; PTEN PHOSPHOHYDROLASE; SMAD4 PROTEIN; STROMAL CELLS; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0032524104     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.280.5366.1036     Document Type: Article

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14. We thank I. Vogelstein, S. R. Hamilton, S. E. Kern, R. Parsons, and members of the Johns Hopkins Oncology Center's Molecular Genetics Laboratory for helpful discussion and comments. B. Vogelstein is an Investigator of the Howard Hughes Medical Institute.