-
1
-
-
0033305566
-
Balanced translocation of 10q and 13q, including the PTEN gene, in a boy with an HCG-secreting tumor and the Bannayan-Riley-Ruvalcaba syndrome
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 4665-4670
-
-
Ahmed, S.F.1
Marsh, D.J.2
Weremowicz, S.3
Morton, C.C.4
Williams, D.M.5
Eng, C.6
-
2
-
-
0030770814
-
Deletion of PTEN in a patient with Bannayan-Riley-Ruvalcaba syndrome suggests allelism with Cowden disease
-
(1997)
Am J Med Genet
, vol.71
, pp. 489-493
-
-
Arch, E.M.1
Goodman, B.K.2
Van Wesep, R.A.3
Liaw, D.4
Clarke, K.5
Parsons, R.6
McKusick, V.A.7
Geraghty, M.T.8
-
3
-
-
0034933494
-
PTEN mutations are uncommon in Proteus syndrome
-
(2001)
J Med Genet
, vol.38
, pp. 480-481
-
-
Barker, E.1
Martinez, A.2
Wang, R.3
Bevan, S.4
Murday, V.5
Shipley, J.6
Houlston, R.7
Harper, J.8
-
4
-
-
0032913743
-
Proteus syndrome: Diagnostic criteria, differential diagnosis and patient evaluation
-
(1999)
Am J Med Genet
, vol.84
, pp. 389-395
-
-
Biesecker, L.G.1
Happle, R.2
Mulliken, J.B.3
Weksberg, R.4
Graham, J.M.5
Viljoen, D.L.6
Cohen, M.M.7
-
6
-
-
0034729805
-
PTEN expression is reduced in a subset of sporadic thyroid carcinomas: Evidence that PTEN-growth suppressing activity in thyroid cancer cells is mediated by p27kip1
-
(2000)
Oncogene
, vol.19
, pp. 3146-3155
-
-
Bruni, P.1
Boccia, A.2
Baldasarre, G.3
Trapasso, F.4
Santoro, M.5
Chiappetta, G.6
Fusco, A.7
Viglietto, G.8
-
7
-
-
15444342299
-
Absence of PTEN/MMAC1 germline mutations in sporadic Bannayan-Riley-Ruvalcaba syndrome
-
(1998)
Cancer Res
, vol.58
, pp. 2724-2726
-
-
Carethers, J.M.1
Furnari, F.B.2
Zigman, A.F.3
Lavine, J.E.4
Jones, M.C.5
Graham, G.E.6
Teen, A.S.7
SuHuang, H.J.8
Ha, H.T.9
Chauhan, D.P.10
Chang, C.L.11
Cavanee, W.K.12
Boland, C.R.13
-
8
-
-
0032922723
-
Phenotypic findings of Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome in a family associated with a single germline mutation in PTEN
-
(1999)
J Med Genet
, vol.36
, pp. 360-364
-
-
Celebi, J.T.1
Tsou, H.C.2
Chen, F.F.3
Zhang, H.4
Ping, X.L.5
Lebwohl, M.G.6
Kezis, J.7
Peacocke, M.8
-
10
-
-
0033824956
-
Absence of germline mutations in MINPP1, a phosphatase-encoding gene centromeric of PTEN, in patients with Cowden and Bannayan-Riley-Ruvalcaba syndrome without germline PTEN mutations
-
(2000)
J Med Genet
, vol.37
, pp. 715-717
-
-
Dahia, P.L.M.1
Gimm, P.2
Chi, H.3
Marsh, D.J.4
Reynolds, P.R.5
Eng, C.6
-
13
-
-
0032403139
-
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis
-
(1998)
Cancer Res
, vol.58
, pp. 5285-5290
-
-
Davies, M.A.1
Lu, Y.2
Sano, T.3
Fang, X.4
Tang, P.5
LaPuschin, R.6
Koul, D.7
Bookstein, R.8
Stokoe, D.9
Yung, W.K.A.10
Mills, G.B.11
Steck, P.A.12
-
14
-
-
0034097541
-
Novel germline mutations in the PTEN tumour suppressor gene found in women with multiple cancers
-
(2000)
J Med Genet
, vol.37
, pp. 336-341
-
-
De Vivo, I.1
Gertig, D.2
Nagase, S.3
Hankinson, S.E.4
O'Brien, R.5
Speizer, F.E.6
Parsons, R.7
Hunter, D.J.8
-
21
-
-
0031883606
-
Genetics of Cowden syndrome: Through the looking glass of oncology
-
(1998)
Int J Oncol
, vol.12
, pp. 701-710
-
-
-
22
-
-
0033738748
-
Will the real Cowden syndrome please stand up: Revised diagnostic criteria
-
(2000)
J Med Genet
, vol.37
, pp. 828-830
-
-
-
23
-
-
0034967198
-
To be or not to BMP
-
(2001)
Nat Genet
, vol.28
, pp. 105-107
-
-
-
24
-
-
18244377693
-
Interpretation of molecular epidemiologic research: Blinded comparison of methods for detecting germline BRCA1 mutations
-
(2001)
J Med Genet
, vol.38
, pp. 824-833
-
-
Eng, C.1
Brody, L.C.2
Wagner, T.M.U.3
Devilee, P.4
Vijg, J.5
Szabo, C.6
Tavtigian, S.7
Nathanson, K.L.8
Ostrander, E.9
Frank, T.S.10
-
25
-
-
0031971514
-
Molecular classification of the inherited hamartoma polyposis syndromes: Clearing the muddied waters
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1020-1022
-
-
Eng, C.1
Ji, H.2
-
30
-
-
0033843623
-
Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors
-
(2000)
Am J Pathol
, vol.156
, pp. 1693-1700
-
-
Gimm, O.1
Perren, A.2
Weng, L.P.3
Marsh, D.J.4
Yeh, J.J.5
Ziebold, U.6
Gil, E.7
Hinze, R.8
Delbridge, L.9
Lees, J.A.10
Robinson, B.G.11
Komminoth, P.12
Dralle, H.13
Eng, C.14
-
32
-
-
0032583122
-
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathway
-
(1998)
J Cell Biol
, vol.143
, pp. 1375-1383
-
-
Gu, J.1
Tamura, M.2
Yamada, K.M.3
-
33
-
-
0034131260
-
Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
-
(2000)
Cancer Res
, vol.60
, pp. 3147-3151
-
-
Hah, S.-Y.1
Kato, H.2
Suzuki, T.3
Shibata, H.4
Ishii, S.5
Shiba, K.6
Matsuno, S.7
Kanamaru, R.8
Ishioka, C.9
-
35
-
-
0032495530
-
A serine/threonine kinase gene defective in Peutz-Jeghers syndrome
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
Bignell, G.7
Aminoff, W.M.8
Högland, P.9
Järvinen, H.10
Kristo, P.11
Pelin, K.12
Ridanpää, M.13
Salovaara, R.14
Toro, T.15
Bodmer, W.16
Olschwang, S.17
Olsen, A.S.18
Stratton, M.R.19
De la Chapelle, A.20
Aaltonen, L.A.21
more..
-
36
-
-
0031012344
-
Localisation of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
-
(1997)
Nat Genet
, vol.15
, pp. 87-90
-
-
Hemminki, A.1
Tomlinson, I.2
Markie, D.3
Järvinen, H.4
Sistonen, P.5
Björkqvist, A.-M.6
Knuutila, S.7
Salovaara, R.8
Bodmer, W.9
Shibata, D.10
De la Chapelle, A.11
Aaltonen, L.A.12
-
38
-
-
0034972978
-
Germline mutations of BMPR1A in juvenile polyposis
-
(2001)
Nat Genet
, vol.28
, pp. 184-187
-
-
Howe, J.R.1
Blair, J.A.2
Sayed, M.G.3
Anderson, M.E.4
Mitros, F.A.5
Petersen, G.M.6
Velculescu, V.E.7
Traverso, G.8
Vogelstein, B.9
-
40
-
-
0032524069
-
Mutations in the SMAD4/DPC4 gene in juvenile polyposis
-
(1998)
Science
, vol.280
, pp. 1086-1088
-
-
Howe, J.R.1
Roth, S.2
Ringold, J.C.3
Summers, R.W.4
Jarvinen, H.J.5
Sistonen, P.6
Tomlinson, I.P.M.7
Houlston, R.S.8
Bevan, S.9
Mitros, F.A.10
Stone, E.M.11
Aaltonen, L.A.12
-
41
-
-
0034671759
-
Genetic heterogeneity in familial juvenile polyposis
-
(2000)
Cancer Res
, vol.60
, pp. 6882-6885
-
-
Huang, S.C.1
Chen, C.R.2
Lavine, J.E.3
Taylor, S.F.4
Newbury, R.O.5
Pham, T.T.6
Ricciardiello, L.7
Carethers, J.M.8
-
43
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
(1998)
Nat Genet
, vol.18
, pp. 38-44
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
Müller, O.7
Back, W.8
Zimmer, M.9
-
44
-
-
0008680296
-
Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure
-
(1998)
Proc Natl Acad Sci USA
, vol.85
, pp. 7164-7168
-
-
Joseph, J.L.1
LeBeau, M.M.2
Jamieson, G.A.3
Acharya, S.4
Shows, T.B.5
Rowley, J.D.6
Sukhatme, V.P.7
-
46
-
-
0035190026
-
Cellular function of phosphoinositide 3-kinases: Implications for development, homeostasis, and cancer
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 615-675
-
-
Katso, R.1
Okkenbaug, K.2
Ahmadi, K.3
White, S.4
Timms, J.5
Waterfield, M.D.6
-
49
-
-
0034652102
-
A role for nuclear PTEN in neuronal differentiation
-
(2000)
J Neurosci
, vol.20
, pp. 1404-1413
-
-
Lachyankar, M.B.1
Sultana, N.2
Schonhoff, C.M.3
Mitra, P.4
Poluha, W.5
Lambert, S.6
Quesenberry, P.J.7
Litofsky, N.S.8
Recht, L.D.9
Nabi, R.10
Miller, S.J.11
Ohta, S.12
Neel, B.G.13
Ross, A.H.14
-
50
-
-
0033615538
-
Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association
-
(1999)
Cell
, vol.99
, pp. 323-334
-
-
Lee, J.1
Yang, H.2
Georgescu, M.-M.3
Di Cristafano, A.4
Maehama, T.5
Shi, Y.6
Dixon, J.E.7
Pandolfi, P.8
Pavletich, N.P.9
-
51
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor B
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.-M.1
Sun, H.2
-
53
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast and prostate cancer
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittman, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
54
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
(1997)
Nat Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.M.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
55
-
-
17344364602
-
Mutations of PTEN in patients with Bannayan-Riley-Ruvalcaba phenotype
-
(1998)
J Med Genet
, vol.35
, pp. 886-889
-
-
Longy, M.1
Coulon, V.2
Duboué, D.A.3
Larrègue, M.4
Eng, C.5
Amati, P.6
Kraimps, J.-L.7
Bottani, A.8
Lacombe, D.9
Bonneau, D.10
-
57
-
-
17344363637
-
Inherited mutations in PTEN that are associated with breast cancer, Cowden syndrome, and juvenile polyposis
-
(1997)
Am J Hum Genet
, vol.61
, pp. 1254-1260
-
-
Lynch, E.D.1
Ostermeyer, E.A.2
Lee, M.K.3
Arena, J.F.4
Ji, H.5
Dann, J.6
Swisshelm, K.7
Suchard, D.8
MacLeod, P.M.9
Kvinnsland, S.10
Gjertsen, B.T.11
Heimdal, K.12
Lubs, H.13
Møller, P.14
King, M.-C.15
-
58
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger phosphoinositol 3,4,5-triphosphate
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
61
-
-
17344368045
-
Germline PTEN mutations in Cowden syndrome-like families
-
(1998)
J Med Genet
, vol.35
, pp. 881-885
-
-
Marsh, D.J.1
Caron, S.2
Dahia, P.L.M.3
Kum, J.B.4
Frayling, I.M.5
Tomlinson, I.P.M.6
Hughes, K.S.7
Hodgson, S.V.8
Murday, V.A.9
Houlston, R.10
Eng, C.11
-
62
-
-
6844252284
-
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
-
(1998)
Hum Mol Genet
, vol.7
, pp. 507-515
-
-
Marsh, D.J.1
Coulon, V.2
Lunetta, K.L.3
Rocca-Serra, P.4
Dahia, P.L.M.5
Zheng, Z.6
Liaw, D.7
-
67
-
-
0035328703
-
Growth and gene expression profile analyses of endometrial cancer cells expressing exogenous PTEN
-
(2001)
Cancer Res
, vol.61
, pp. 3741-3749
-
-
Matsushima-Nishiu, M.1
Unoki, M.2
Oho, K.3
Tsunoda, T.4
Minagucki, T.5
Kuramoto, H.6
Nishida, M.7
Satoh, T.8
Tanaka, T.9
Nakamura, Y.10
-
70
-
-
0035964367
-
Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10031-10033
-
-
Mills, G.B.1
Lu, Y.2
Kohn, E.C.3
-
73
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor suppressor function
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van der Kaay, J.4
Storalov, J.P.5
Hemmings, B.A.6
Wigler, M.H.7
Downes, C.P.8
Tonks, N.K.9
-
74
-
-
0030837555
-
PTEN, the tumor suppressor from human chromosome 10q23, is a dual specificity phosphatase
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
76
-
-
0001259749
-
NCCN practice guidelines: Genetics/familial high risk cancer
-
(1999)
Oncology
, vol.13
, pp. 161-186
-
-
-
77
-
-
0032905101
-
Novel PTEN mutations in patients with Cowden disease: Absence of clear genotype-phenotype correlations
-
(1999)
Eur J Hum Genet
, vol.7
, pp. 267-273
-
-
Nelen, M.R.1
Kremer, H.2
Konings, I.B.M.3
Schoute, F.4
Van Essen, A.J.5
Koch, R.6
Woods, C.G.7
Fryns, J.-P.8
Hamel, B.9
Hoefsloot, L.H.10
Peeters, E.A.J.11
Padberg, G.W.12
-
78
-
-
0030140025
-
Localization of the gene for Cowden disease to 10122-23
-
(1996)
Nat Genet
, vol.13
, pp. 114-116
-
-
Nelen, M.R.1
Padberg, G.W.2
Peeters, E.A.J.3
Lin, A.Y.4
Van den Helm, B.5
Frants, R.R.6
Coulon, V.7
Goldstein, A.M.8
Van Reen, M.M.M.9
Easton, D.F.10
Eeles, R.A.11
Hodgson, S.12
Mulvihill, J.J.13
Murday, V.A.14
Tucker, M.A.15
Mariman, E.C.M.16
Starink, T.M.17
Ponder, B.A.J.18
Ropers, H.H.19
Kremer, H.20
Longy, M.21
Eng, C.22
more..
-
79
-
-
8544247944
-
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1383-1387
-
-
Nelen, M.R.1
Van Staveren, C.G.2
Peeters, E.A.J.3
Ben Hassel, M.4
Gorlin, R.J.5
Hamm, H.6
Lindboe, C.F.7
Fryns, J.-P.8
Sijmons, R.H.9
Woods, D.G.10
Mariman, E.C.M.11
Padberg, G.W.12
Kremer, H.13
-
80
-
-
17944377486
-
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10314-10319
-
-
Neshat, M.S.1
Mellinghoff, I.K.2
Tran, C.3
Stiles, B.4
Thomas, G.5
Petersen, R.6
Frost, P.7
Gibbons, J.J.8
Wu, H.9
Sawyers, C.L.10
-
85
-
-
0033809990
-
Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells
-
(2000)
Am J Pathol
, vol.157
, pp. 1097-1103
-
-
Perren, A.1
Komminoth, P.2
Saremaslani, P.3
Matter, C.4
Feurer, S.5
Lees, J.A.6
Heitz, P.U.7
Eng, C.8
-
87
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
Cordon-Cardo, C.7
Catoretti, G.8
Fisher, P.E.9
Parsons, R.10
-
88
-
-
0035666018
-
A novel germline mutation of the PTEN gene in a patient with macrocephaly, ventricular dilatation and features of VATER association
-
(2001)
J Med Genet
, vol.38
, pp. 820-823
-
-
Reardon, W.1
Zhou, X.P.2
Eng, C.3
-
91
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
(2001)
Mol Cell
, vol.8
, pp. 317-325
-
-
Stambolic, V.1
MacPherson, D.2
Sas, D.3
Lin, Y.4
Snow, B.5
Jang, Y.6
Benchimol, S.7
Mak, T.W.8
-
92
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
(1998)
Cell
, vol.95
, pp. 1-20
-
-
Stambolic, V.1
Suzuki, A.2
De la Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Rulland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
95
-
-
17144436629
-
Identification of a candidate turnout suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.A.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.F.14
Tavtigian, S.V.15
-
96
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
(1998)
Curr Biol
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
De la Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
Del Barco Barrantes, I.6
Ho, A.7
Wakeham, A.8
Itie, A.9
Khoo, W.10
Fukumoto, M.11
Mak, T.W.12
-
97
-
-
0031806534
-
Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4109-4117
-
-
Takahashi-Tezuka, M.1
Yoshida, Y.2
Fukada, T.3
Ohtani, T.4
Yamanaka, Y.5
Nishida, K.6
Nakajima, K.7
Hibi, M.8
Hirano, T.9
-
100
-
-
0035847102
-
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
-
(2001)
J Biol Chem
, vol.276
, pp. 993-998
-
-
Torres, J.1
Pulido, R.2
-
101
-
-
16944362877
-
Role of MMAC1 mutations in early onset breast cancer: Causative in association with Cowden's syndrome and excluded in BRCA1-negative cases
-
(1997)
Am J Hum Genet
, vol.61
, pp. 1036-1043
-
-
Tsou, H.C.1
Teng, D.2
Ping, X.L.3
Broncolini, V.4
Davis, T.5
Hu, R.6
Xie, X.-X.7
Gruener, A.C.8
Schrager, C.A.9
Christiano, A.M.10
Eng, C.11
Steck, P.12
Ott, J.13
Tavtigian, S.V.14
Peacocke, M.15
-
102
-
-
0035958558
-
Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway
-
(2001)
Oncogene
, vol.20
, pp. 4457-4465
-
-
Unoki, M.1
Nakamura, Y.2
-
107
-
-
0035869212
-
PTEN coordinates G1 arrest by down regulating cyclin D1 via its protein phosphatase activity and up regulating p27 via its lipid phosphatase activity
-
(2001)
Hum Mol Genet
, vol.10
, pp. 599-604
-
-
Weng, L.P.1
Brown, J.L.2
Eng, C.3
-
108
-
-
0035253607
-
PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and independent pathways
-
(2001)
Hum Mol Genet
, vol.10
, pp. 237-242
-
-
-
112
-
-
0034636038
-
Evidence for regulation of PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAG1-2
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 4233-4238
-
-
Wu, X.1
Hepner, K.2
Castello-Prabhu, S.3
Do, D.4
Kaye, M.B.5
Yuan, X.J.6
Wood, J.7
Ross, C.8
Sawyers, C.L.9
Whang, Y.E.10
-
113
-
-
0034647496
-
Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase
-
(2000)
J Biol Chem
, vol.275
, pp. 21477-21485
-
-
Wu, Y.1
Dowbenko, D.2
Spencer, S.3
Laura, R.4
Lee, J.5
Gu, Q.6
Lasky, L.A.7
-
114
-
-
0035937767
-
A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor
-
(2001)
J Biol Chem
, vol.276
, pp. 8856-8864
-
-
Yart, A.1
Laffargue, M.2
Mayeux, P.3
Chretien, S.4
Peres, C.5
Tonks, N.6
Roche, S.7
Payrastre, B.8
Chap, H.9
Raynal, P.10
-
115
-
-
0035928416
-
Association of germline mutation in the PTEN tumour suppressor gene and a subset of Proteus sand Proteus-like syndromes
-
(2001)
Lancet
, vol.358
, pp. 210-211
-
-
Zhou, X.P.1
Hampel, H.2
Thiele, H.3
Gorlin, R.J.4
Hennekam, R.5
Parisi, M.6
Winter, R.M.7
Eng, C.8
-
116
-
-
0034701247
-
Germline and germline mosaic mutations associated with a Proteus-like syndrome of hemihypertrophy, lower limb asymmetry, arterio-venous malformations and lipomatosis
-
(2000)
Hum Mol Genet
, vol.9
, pp. 765-768
-
-
Zhou, X.P.1
Marsh, D.J.2
Hampel, H.3
Mulliken, J.B.4
Gimm, O.5
Eng, C.6
|