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Volumn 16, Issue 6, 1998, Pages 413-428

The HER-2/neu oncogene in breast cancer: Prognostic factor, predictive factor, and target for therapy

Author keywords

Breast neoplasms; HER 2 neu; Prognosis; Proto oncogene c erbB2; Therapy

Indexed keywords

DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MONOCLONAL ANTIBODY;

EID: 0031759864     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.160413     Document Type: Article
Times cited : (635)

References (125)
  • 1
    • 0023952496 scopus 로고
    • Amplification of C-ERB-B2 and aggressive breast tumors?
    • Slamon DJ, Clark GM. Amplification of C-ERB-B2 and aggressive breast tumors? Science 1988;240:1795-1798.
    • (1988) Science , vol.240 , pp. 1795-1798
    • Slamon, D.J.1    Clark, G.M.2
  • 2
    • 0028127473 scopus 로고
    • The neu oncogene: More than a prognostic indicator?
    • De Potter CR. The neu oncogene: more than a prognostic indicator? Hum Pathol 1994;25:1264-1268.
    • (1994) Hum Pathol , vol.25 , pp. 1264-1268
    • De Potter, C.R.1
  • 3
    • 0029312619 scopus 로고
    • Interaction between ERB-receptors and heregulin in breast cancer tumor progression and drug resistance
    • Lupu R, Cardillo M, Harris L et al. Interaction between ERB-receptors and heregulin in breast cancer tumor progression and drug resistance. Sem Cancer Biol 1995;6:135-145.
    • (1995) Sem Cancer Biol , vol.6 , pp. 135-145
    • Lupu, R.1    Cardillo, M.2    Harris, L.3
  • 4
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the Her-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the Her-2/neu oncogene. Science 1987;235:177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 5
    • 0023857935 scopus 로고
    • Correlation of c-erb B2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading
    • Berger MS, Locher GW, Saurer S et al. Correlation of c-erb B2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading. Cancer Res 1988;48:1238-1243.
    • (1988) Cancer Res , vol.48 , pp. 1238-1243
    • Berger, M.S.1    Locher, G.W.2    Saurer, S.3
  • 7
    • 0025332351 scopus 로고
    • Amplification of the c-erb B-2 oncogene in prognosis of breast adenocarcinoma
    • Heintz NH, Leslie KO, Rogers LA et al. Amplification of the c-erb B-2 oncogene in prognosis of breast adenocarcinoma. Arch Pathol Lab Med 1990;114:160-163.
    • (1990) Arch Pathol Lab Med , vol.114 , pp. 160-163
    • Heintz, N.H.1    Leslie, K.O.2    Rogers, L.A.3
  • 8
    • 0025213177 scopus 로고
    • Correlation between histologic grade of malignancy and copy number of c-erbB-2 gene in breast carcinoma. A retrospective analysis of 176 cases
    • Tsuda H, Hirohashi S, Shimosato Y et al. Correlation between histologic grade of malignancy and copy number of c-erbB-2 gene in breast carcinoma. A retrospective analysis of 176 cases. Cancer 1990; 65:1794-1800.
    • (1990) Cancer , vol.65 , pp. 1794-1800
    • Tsuda, H.1    Hirohashi, S.2    Shimosato, Y.3
  • 9
    • 0025360473 scopus 로고
    • HER-2/new amplification predicts poor survival in node-positive breast cancer
    • Borg A, Tandon AK, Sigurdsson H et al. HER-2/new amplification predicts poor survival in node-positive breast cancer. Cancer Res 1990;50:4332-4337.
    • (1990) Cancer Res , vol.50 , pp. 4332-4337
    • Borg, A.1    Tandon, A.K.2    Sigurdsson, H.3
  • 10
    • 0025177290 scopus 로고
    • Pathologic findings from the nations' surgical adjuvant breast and bowel project: Prognostic significance of erb B2 protein overexpression in primary breast cancer
    • Paik S, Hazan R, Fisher ER et al. Pathologic findings from the nations' surgical adjuvant breast and bowel project: prognostic significance of erb B2 protein overexpression in primary breast cancer. J Clin Oncol 1990;8:103-112.
    • (1990) J Clin Oncol , vol.8 , pp. 103-112
    • Paik, S.1    Hazan, R.2    Fisher, E.R.3
  • 11
    • 0026198298 scopus 로고
    • Immunohistochemical assay of neu/c-erb B-2 oncogene product in paraffin-embedded tissues in early breast cancer: Retrospective follow-up study of 245 stage I and II cases
    • Battifora H, Gaffey M, Esteban J et al. Immunohistochemical assay of neu/c-erb B-2 oncogene product in paraffin-embedded tissues in early breast cancer: Retrospective follow-up study of 245 stage I and II cases. Modern Pathol 1991;4:466-474.
    • (1991) Modern Pathol , vol.4 , pp. 466-474
    • Battifora, H.1    Gaffey, M.2    Esteban, J.3
  • 12
    • 0026059293 scopus 로고
    • Association of C-erb B2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer
    • Kallioniemi OP, Holli K, Visakorpi T et al. Association of C-erb B2 protein over-expression with high rate of cell proliferation, increased risk of visceral metastasis and poor long-term survival in breast cancer. Int J Cancer 1991;49:650-655.
    • (1991) Int J Cancer , vol.49 , pp. 650-655
    • Kallioniemi, O.P.1    Holli, K.2    Visakorpi, T.3
  • 13
    • 0026019357 scopus 로고
    • Follow-up study of HER-2/nen amplification in primary breast cancer
    • Clark GM, McGuire WL. Follow-up study of HER-2/nen amplification in primary breast cancer. Cancer Res 1991;51:944-948.
    • (1991) Cancer Res , vol.51 , pp. 944-948
    • Clark, G.M.1    McGuire, W.L.2
  • 14
    • 0026012037 scopus 로고
    • C-erb B2 oncoprotein expression in primary and advanced breast cancer
    • Lovekin C, Ellis IO, Locker A et al. C-erb B2 oncoprotein expression in primary and advanced breast cancer. Br J Cancer 1991;63:439-443.
    • (1991) Br J Cancer , vol.63 , pp. 439-443
    • Lovekin, C.1    Ellis, I.O.2    Locker, A.3
  • 15
    • 0025743925 scopus 로고
    • Prognostic significance of C-erb B2 and estrogen receptor status in human breast cancer
    • McCann AH, DeDervan TA, O'Regan M et al. Prognostic significance of C-erb B2 and estrogen receptor status in human breast cancer. Cancer Res 1991;51:3296-3303.
    • (1991) Cancer Res , vol.51 , pp. 3296-3303
    • McCann, A.H.1    DeDervan, T.A.2    O'Regan, M.3
  • 16
    • 0026092572 scopus 로고
    • Long term survival in breast cancer related to overexpression of the C-erb B2 oncoprotein: An immunohistochemical study using monoclonal antibody NCL-CB11
    • Dykens R, Corbett IP, Henry J et al. Long term survival in breast cancer related to overexpression of the C-erb B2 oncoprotein: an immunohistochemical study using monoclonal antibody NCL-CB11. J Pathol 1991;163:105-110.
    • (1991) J Pathol , vol.163 , pp. 105-110
    • Dykens, R.1    Corbett, I.P.2    Henry, J.3
  • 17
    • 0025781290 scopus 로고
    • Prognostic significance of UER-2/neu expression in breast cancer and its relationship to other prognostic factors
    • Rilke F, Colnaghi MI, Cascinelli N et al. Prognostic significance of UER-2/neu expression in breast cancer and its relationship to other prognostic factors. Int J Cancer 1991;49:44-49.
    • (1991) Int J Cancer , vol.49 , pp. 44-49
    • Rilke, F.1    Colnaghi, M.I.2    Cascinelli, N.3
  • 18
    • 0026022494 scopus 로고
    • The long term prognostic significance of C-erb B2 in primary breast cancer
    • Winstanley J, Cooke T, Murray GD et al. The long term prognostic significance of C-erb B2 in primary breast cancer. Br J Cancer 1991;63:447-450.
    • (1991) Br J Cancer , vol.63 , pp. 447-450
    • Winstanley, J.1    Cooke, T.2    Murray, G.D.3
  • 19
    • 0026063874 scopus 로고
    • The relationship between C-erb B2 expression, and s-phase fraction in prognosis in breast cancer
    • O'Reilly SM, Barnes DM, Camplejohn RS et al. The relationship between C-erb B2 expression, and s-phase fraction in prognosis in breast cancer. Br J Cancer 1991;63:444-446.
    • (1991) Br J Cancer , vol.63 , pp. 444-446
    • O'Reilly, S.M.1    Barnes, D.M.2    Camplejohn, R.S.3
  • 20
    • 0026004309 scopus 로고
    • Correlation between C-erb B2 amplification and risk of recurrent disease in node-negative breast cancer
    • Paterson MC, Dietrich KD, Danyluk J et al. Correlation between C-erb B2 amplification and risk of recurrent disease in node-negative breast cancer. Cancer Res 1991;51:556-567.
    • (1991) Cancer Res , vol.51 , pp. 556-567
    • Paterson, M.C.1    Dietrich, K.D.2    Danyluk, J.3
  • 21
    • 0026650016 scopus 로고
    • Prognostic significance of Her-2 oncoprotein expression in breast cancer: A 30-year follow up
    • Toikkanen S, Helin H, Isola J et al. Prognostic significance of Her-2 oncoprotein expression in breast cancer: a 30-year follow up. J Clin Oncol 1992;10:1044-1048.
    • (1992) J Clin Oncol , vol.10 , pp. 1044-1048
    • Toikkanen, S.1    Helin, H.2    Isola, J.3
  • 22
    • 0027083049 scopus 로고
    • Expression of HER-2/neu oncoprotein in breast cancer: A comparison of immunohistochemical and western blot techniques
    • Molina R, Ciocca DR, Candon AK et al. Expression of HER-2/neu oncoprotein in breast cancer: a comparison of immunohistochemical and western blot techniques. Anticancer Res 1992;12:1965-1991.
    • (1992) Anticancer Res , vol.12 , pp. 1965-1991
    • Molina, R.1    Ciocca, D.R.2    Candon, A.K.3
  • 23
    • 0026708767 scopus 로고
    • c-erb B-2 oncoprotein expression versus internal mammary lymph node metastases as additional prognostic factors in patients with axillary lymph node-positive breast cancer
    • Noguchi M, Koyasaki M, Ohta N et al. c-erb B-2 oncoprotein expression versus internal mammary lymph node metastases as additional prognostic factors in patients with axillary lymph node-positive breast cancer. Cancer 1992;69:2953-2960.
    • (1992) Cancer , vol.69 , pp. 2953-2960
    • Noguchi, M.1    Koyasaki, M.2    Ohta, N.3
  • 24
    • 0026576399 scopus 로고
    • HER-2/neu node-negative breast cancer: Prognostic significance of overexpression influenced by the presence of in-situ carcinoma
    • Allred DC, Clark GM, Tandon AK et al. HER-2/neu node-negative breast cancer: prognostic significance of overexpression influenced by the presence of in-situ carcinoma. J Clin Oncol 1992;10:599-605.
    • (1992) J Clin Oncol , vol.10 , pp. 599-605
    • Allred, D.C.1    Clark, G.M.2    Tandon, A.K.3
  • 25
    • 0026748197 scopus 로고
    • Significance of c-erb B-2 amplification in DNA aneuploidy. Analysis in 78 patients with node-negative breast cancer
    • Babiak J, Hugh J, Poppeme S. Significance of c-erb B-2 amplification in DNA aneuploidy. Analysis in 78 patients with node-negative breast cancer. Cancer 1992;70:770-776.
    • (1992) Cancer , vol.70 , pp. 770-776
    • Babiak, J.1    Hugh, J.2    Poppeme, S.3
  • 26
    • 0026582760 scopus 로고
    • HER-2/neu amplification and overexpression in primary human breast cancer is associated with early metastasis
    • Tiwari RK, Borgen PI, Wong GY et al. HER-2/neu amplification and overexpression in primary human breast cancer is associated with early metastasis. Anticancer Res 1992;12:419-426.
    • (1992) Anticancer Res , vol.12 , pp. 419-426
    • Tiwari, R.K.1    Borgen, P.I.2    Wong, G.Y.3
  • 27
    • 0026625217 scopus 로고
    • Prognostic importance of C-erb B2 expression in breast cancer
    • Gusterson BA, Gelber RD, Goldhirsch A et al. Prognostic importance of C-erb B2 expression in breast cancer. J Clin Oncol 1992;10:1049-1056.
    • (1992) J Clin Oncol , vol.10 , pp. 1049-1056
    • Gusterson, B.A.1    Gelber, R.D.2    Goldhirsch, A.3
  • 28
    • 0027522624 scopus 로고
    • Prognostic significance of C-erb B2 expression in node negative breast cancer
    • Bianchi S, Paglierani M, Zampi G et al. Prognostic significance of C-erb B2 expression in node negative breast cancer. Br J Cancer 1993;67:625-629.
    • (1993) Br J Cancer , vol.67 , pp. 625-629
    • Bianchi, S.1    Paglierani, M.2    Zampi, G.3
  • 29
    • 0027363077 scopus 로고
    • Her-2/neu expression in node-negative breast cancer: Direct tissue quantification by computerized image analysis and association of overexpression with increased risk of recurrent disease
    • Press MF, Pike MC, Chazin VR et al. Her-2/neu expression in node-negative breast cancer: direct tissue quantification by computerized image analysis and association of overexpression with increased risk of recurrent disease. Cancer Res 1993;53:4960-4970.
    • (1993) Cancer Res , vol.53 , pp. 4960-4970
    • Press, M.F.1    Pike, M.C.2    Chazin, V.R.3
  • 30
    • 0027517374 scopus 로고
    • Clinical significance of Her-2/neu oncogene amplification in primary breast cancer
    • Seshadri R, Firgaira FA, Horsfall DJ et al. Clinical significance of Her-2/neu oncogene amplification in primary breast cancer. J Clin Oncol 1993;11:1936-1942.
    • (1993) J Clin Oncol , vol.11 , pp. 1936-1942
    • Seshadri, R.1    Firgaira, F.A.2    Horsfall, D.J.3
  • 31
    • 0027477516 scopus 로고
    • Human breast cancer: Correlation study between Her-2/neu amplification and prognostic factors in an unselected population
    • Descotes F, Pavy J-J, Adessi GL. Human breast cancer: correlation study between Her-2/neu amplification and prognostic factors in an unselected population. Anticancer Res 1993;13:119-124.
    • (1993) Anticancer Res , vol.13 , pp. 119-124
    • Descotes, F.1    Pavy, J.-J.2    Adessi, G.L.3
  • 32
    • 0027993527 scopus 로고
    • Prognostic and predictive relevance of C-erb B2 and ras expression in node-positive and negative breast cancer
    • Giai M, Roagna R, Ponzone R et al. Prognostic and predictive relevance of C-erb B2 and ras expression in node-positive and negative breast cancer. Anticancer Res 1994;14:1441-1450.
    • (1994) Anticancer Res , vol.14 , pp. 1441-1450
    • Giai, M.1    Roagna, R.2    Ponzone, R.3
  • 33
    • 0028354305 scopus 로고
    • Cerb-B2 expression and response to adjuvant therapy in women with node-positive early breast cancer
    • Muss HB, Thor AD, Berry DA et al. Cerb-B2 expression and response to adjuvant therapy in women with node-positive early breast cancer. N Engl J Med 1994;330:1260-1266.
    • (1994) N Engl J Med , vol.330 , pp. 1260-1266
    • Muss, H.B.1    Thor, A.D.2    Berry, D.A.3
  • 34
    • 0028301750 scopus 로고
    • Prognostic significance of Her-2/neu oncogene expression in node-positive breast cancer. the influence of the pattern of immunostaining and adjuvant therapy
    • Tetu B, Brisson J. Prognostic significance of Her-2/neu oncogene expression in node-positive breast cancer. The influence of the pattern of immunostaining and adjuvant therapy. Cancer 1994;73:2359-2365.
    • (1994) Cancer , vol.73 , pp. 2359-2365
    • Tetu, B.1    Brisson, J.2
  • 35
    • 0028143956 scopus 로고
    • Prognostic value of CerbB2 overexpression in axillary lymph node-positive breast cancer. Results from a randomized adjuvant treatment protocol
    • Hartmann LC, Ingle JN, Wold LE et al. Prognostic value of CerbB2 overexpression in axillary lymph node-positive breast cancer. Results from a randomized adjuvant treatment protocol. Cancer 1994;74:2956-2963.
    • (1994) Cancer , vol.74 , pp. 2956-2963
    • Hartmann, L.C.1    Ingle, J.N.2    Wold, L.E.3
  • 36
    • 0028652334 scopus 로고
    • Breast cancer response to adjuvant chemotherapy in correlation with erb B2 and p53 expression
    • Jacquemier J, Penault-Llorca P, Viens P et al. Breast cancer response to adjuvant chemotherapy in correlation with erb B2 and p53 expression. Anticancer Res 1994;14:2773-2778.
    • (1994) Anticancer Res , vol.14 , pp. 2773-2778
    • Jacquemier, J.1    Penault-Llorca, P.2    Viens, P.3
  • 37
    • 0028209683 scopus 로고
    • Overexpression of p53 and Her-2/neu proteins as prognostic markers in early stage breast cancer
    • Marks JR, Humphrey PA, Wu K at al. Overexpression of p53 and Her-2/neu proteins as prognostic markers in early stage breast cancer. Ann Surg 1994;219:332-341.
    • (1994) Ann Surg , vol.219 , pp. 332-341
    • Marks, J.R.1    Humphrey, P.A.2    Wu, K.3
  • 38
    • 0028938935 scopus 로고
    • Immunohistochemical detection of Her-2/neu expression in patients with axillary lymph node-negative breast carcinoma. A study of epidemiologic risk factors, histologic features and prognosis
    • Rosen PP, Lesser ML, Arroyo CD et al. Immunohistochemical detection of Her-2/neu expression in patients with axillary lymph node-negative breast carcinoma. A study of epidemiologic risk factors, histologic features and prognosis. Cancer 1995;75:1320-1326.
    • (1995) Cancer , vol.75 , pp. 1320-1326
    • Rosen, P.P.1    Lesser, M.L.2    Arroyo, C.D.3
  • 39
    • 0029038721 scopus 로고
    • The prognostic value of c-erbB2 in primary breast carcinomas: A study on 942 cases
    • Quenel N, Wafflart J, Bonichon F et al. The prognostic value of c-erbB2 in primary breast carcinomas: a study on 942 cases. Breast Cancer Res Treat 1995;35:283-291.
    • (1995) Breast Cancer Res Treat , vol.35 , pp. 283-291
    • Quenel, N.1    Wafflart, J.2    Bonichon, F.3
  • 40
    • 0030010117 scopus 로고    scopus 로고
    • Carcinoembryonic expression in stages I and II breast cancer; its relationship with clinicopathologic factors
    • Sundblad AS, Pellicer EM, Ricci L. Carcinoembryonic expression in stages I and II breast cancer; its relationship with clinicopathologic factors. Hum Pathol 1996;27:297-300.
    • (1996) Hum Pathol , vol.27 , pp. 297-300
    • Sundblad, A.S.1    Pellicer, E.M.2    Ricci, L.3
  • 41
    • 16044373760 scopus 로고    scopus 로고
    • The predictive power of semiquantitative immunohistochemical assessment of p53 and C-erbB2 in lymph node-negative breast cancer
    • O'Malley FP, Saad Z, Kerkvliet N et al. The predictive power of semiquantitative immunohistochemical assessment of p53 and C-erbB2 in lymph node-negative breast cancer. Hum Pathol 1996;27:955-963.
    • (1996) Hum Pathol , vol.27 , pp. 955-963
    • O'Malley, F.P.1    Saad, Z.2    Kerkvliet, N.3
  • 42
    • 0006381404 scopus 로고    scopus 로고
    • Her-2/neu and p53 expression in breast cancer: Valid prognostic markers when assessed by direct immunoassay, but not by immunochemistry
    • Hieken TJ, Mehta RR, Shilkaitis A et al. Her-2/neu and p53 expression in breast cancer: valid prognostic markers when assessed by direct immunoassay, but not by immunochemistry. Proc Annu Meet Am Soc Clin Oncol 1996;15:113a.
    • (1996) Proc Annu Meet Am Soc Clin Oncol , vol.15
    • Hieken, T.J.1    Mehta, R.R.2    Shilkaitis, A.3
  • 43
    • 0029788433 scopus 로고    scopus 로고
    • FISH detection of HER-2/neu oncogene amplification in early onset breast cancer
    • Xing W-R, Gilchrist KW, Harris CP et al. FISH detection of HER-2/neu oncogene amplification in early onset breast cancer. Breast Cancer Res Treat 1996;39:203-212.
    • (1996) Breast Cancer Res Treat , vol.39 , pp. 203-212
    • Xing, W.-R.1    Gilchrist, K.W.2    Harris, C.P.3
  • 44
    • 0030889953 scopus 로고    scopus 로고
    • ErbB2 assay in breast cancer: Possibly improved clinical information using a quantitative method
    • Dittadi R, Brazzale A, Pappagallo G et al. ErbB2 assay in breast cancer: possibly improved clinical information using a quantitative method. Anticancer Res 1997;17:1245-1247.
    • (1997) Anticancer Res , vol.17 , pp. 1245-1247
    • Dittadi, R.1    Brazzale, A.2    Pappagallo, G.3
  • 45
    • 0030854539 scopus 로고    scopus 로고
    • Immunohistochemical expression of p53 and c-erbB-2 in breast carcinoma: Relation with epidemiologic factors, histologic features and prognosis
    • Fernandez-Acenero MJ, Farina Gonzalez J, Arangoncillo Ballesteros P. Immunohistochemical expression of p53 and c-erbB-2 in breast carcinoma: relation with epidemiologic factors, histologic features and prognosis. Gen Diagn Pathol 1997;142:289-296.
    • (1997) Gen Diagn Pathol , vol.142 , pp. 289-296
    • Fernandez-Acenero, M.J.1    Farina Gonzalez, J.2    Arangoncillo Ballesteros, P.3
  • 46
    • 0030865747 scopus 로고    scopus 로고
    • Multivariate analysis of DNA ploidy, p53, c-erbB-2 proteins, EGFR, and steroid hormone receptors for short-term prognosis in breast cancer
    • Eissa S, Khalifa A, el-Gharib A et al. Multivariate analysis of DNA ploidy, p53, c-erbB-2 proteins, EGFR, and steroid hormone receptors for short-term prognosis in breast cancer. Anticancer Res 1997;17:3091-3097.
    • (1997) Anticancer Res , vol.17 , pp. 3091-3097
    • Eissa, S.1    Khalifa, A.2    El-Gharib, A.3
  • 47
    • 0030969502 scopus 로고    scopus 로고
    • c-erbB-2 oncoprotein detected by automated quantitative immunocytochemistry in breast carcinomas correlates with patients' overall and disease-free survival
    • Charpin C, Garcia S, Bouvier C et al. c-erbB-2 oncoprotein detected by automated quantitative immunocytochemistry in breast carcinomas correlates with patients' overall and disease-free survival. Br J Cancer 1997;75:1667-1673.
    • (1997) Br J Cancer , vol.75 , pp. 1667-1673
    • Charpin, C.1    Garcia, S.2    Bouvier, C.3
  • 48
    • 18244422222 scopus 로고    scopus 로고
    • Her-2/neu gene amplification characterized by fluorescence in situ hybridization: Poor prognosis in node-negative breast carcinomas
    • Press MJ, Bernstein L, Thomas PA et al. Her-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas. J Clin Oncol 1997;15:2894-2904.
    • (1997) J Clin Oncol , vol.15 , pp. 2894-2904
    • Press, M.J.1    Bernstein, L.2    Thomas, P.A.3
  • 49
    • 0001870723 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in lymph node negative breast cancer
    • Ross JS, Muraca PJ, Jaffe D et al. Multivariate analysis of prognostic factors in lymph node negative breast cancer. Mod Pathol 1998;11:26a.
    • (1998) Mod Pathol , vol.11
    • Ross, J.S.1    Muraca, P.J.2    Jaffe, D.3
  • 50
    • 0002982830 scopus 로고    scopus 로고
    • cdc2 cyclin dependent kinase and MIB1 overexpression, and HER-2/neu gene amplification detected by fluorescence in-situ hybridization in breast cancer
    • cdc2 cyclin dependent kinase and MIB1 overexpression, and HER-2/neu gene amplification detected by fluorescence in-situ hybridization in breast cancer. Mod Pathol 1998;11:18A.
    • (1998) Mod Pathol , vol.11
    • Depowski, P.L.1    Brien, T.P.2    Sheehan, C.E.3
  • 51
    • 0025916196 scopus 로고
    • Prognosis and breast cancer. Recognition of lethal and favorable prognostic types
    • Page DL. Prognosis and breast cancer. Recognition of lethal and favorable prognostic types. Am J Surg Pathol 1991;15:334-349.
    • (1991) Am J Surg Pathol , vol.15 , pp. 334-349
    • Page, D.L.1
  • 53
    • 0025279110 scopus 로고
    • How to use prognostic factors in axillary node-negative breast cancer patients
    • McGuire WL, Tandon AK, Allred DC et al. How to use prognostic factors in axillary node-negative breast cancer patients. J Natl Cancer Inst 1990;82:1006-1015.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 1006-1015
    • McGuire, W.L.1    Tandon, A.K.2    Allred, D.C.3
  • 54
    • 0029884715 scopus 로고    scopus 로고
    • Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization
    • Pauletti G, Godolphin W, Press MF et al. Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization. Oncogene 1996;13:63-72.
    • (1996) Oncogene , vol.13 , pp. 63-72
    • Pauletti, G.1    Godolphin, W.2    Press, M.F.3
  • 55
    • 0029878915 scopus 로고    scopus 로고
    • Fluorescence in-situ hybridization for detecting ERBB-2 amplification in breast tumor fine needle aspiration biopsies
    • Sauter G, Feichter G, Torhorst J et al. Fluorescence in-situ hybridization for detecting ERBB-2 amplification in breast tumor fine needle aspiration biopsies. Acta Cytol 1996;40:164-173.
    • (1996) Acta Cytol , vol.40 , pp. 164-173
    • Sauter, G.1    Feichter, G.2    Torhorst, J.3
  • 56
    • 0031915998 scopus 로고    scopus 로고
    • Prognostic and predictive factors in breast cancer by immunohistochemical analysis
    • Allred DC, Harvey JM, Berardo M et al. Prognostic and predictive factors in breast cancer by immunohistochemical analysis. Mod Pathol 1998;11:155-168.
    • (1998) Mod Pathol , vol.11 , pp. 155-168
    • Allred, D.C.1    Harvey, J.M.2    Berardo, M.3
  • 57
    • 0029742823 scopus 로고    scopus 로고
    • Loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancer
    • Jacobs TW, Prioleau JE, Stillman IE et al. Loss of tumor marker-immunostaining intensity on stored paraffin slides of breast cancer. J Natl Cancer Inst 1996;88:1054-1059.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1054-1059
    • Jacobs, T.W.1    Prioleau, J.E.2    Stillman, I.E.3
  • 58
    • 0028221475 scopus 로고
    • Optimization of immunohistochemical detection of ERBB2 in human breast cancer: Impact of fixation
    • Penault-Llorca F, Adelaide J, Houvenaeghel G et al. Optimization of immunohistochemical detection of ERBB2 in human breast cancer: impact of fixation. J Pathol 1994;173:65-75.
    • (1994) J Pathol , vol.173 , pp. 65-75
    • Penault-Llorca, F.1    Adelaide, J.2    Houvenaeghel, G.3
  • 59
    • 0028477294 scopus 로고
    • Analysis of C-erb B2 expression using a panel of six commercially available antibodies
    • Busmanis I, Feleppa F, Jones A et al. Analysis of C-erb B2 expression using a panel of six commercially available antibodies. Pathol 1994;26:261-267.
    • (1994) Pathol , vol.26 , pp. 261-267
    • Busmanis, I.1    Feleppa, F.2    Jones, A.3
  • 60
    • 0028232729 scopus 로고
    • Sensitivity of Her-2/neu antibodies in archival tissue samples: Potential source of error in immunohistochemical studies of oncogene expression
    • Press MF, Hung G, Godolphin W et al. Sensitivity of Her-2/neu antibodies in archival tissue samples: potential source of error in immunohistochemical studies of oncogene expression. Cancer Res 1994;54:2771-2777.
    • (1994) Cancer Res , vol.54 , pp. 2771-2777
    • Press, M.F.1    Hung, G.2    Godolphin, W.3
  • 61
    • 0030680173 scopus 로고    scopus 로고
    • A scoring system for immunohistochemical staining: Consensus report of the Task Force for Basic Research of the EORTC-GCGC
    • vanDiest PJ, vanDam P, Henzen-Logmans SC et al. A scoring system for immunohistochemical staining: consensus report of the Task Force for Basic Research of the EORTC-GCGC. J Clin Pathol 1997;50:801-804.
    • (1997) J Clin Pathol , vol.50 , pp. 801-804
    • VanDiest, P.J.1    VanDam, P.2    Henzen-Logmans, S.C.3
  • 62
    • 0025455197 scopus 로고
    • Immunohistochemical evaluation of cerb B2 oncogene expression in ductal carcinoma in situ and atypical ductal hyperplasia of the breast
    • Lodato RF, Maguire HC, Greene MI et al. Immunohistochemical evaluation of cerb B2 oncogene expression in ductal carcinoma in situ and atypical ductal hyperplasia of the breast. Mod Pathol 1990;3:449-454.
    • (1990) Mod Pathol , vol.3 , pp. 449-454
    • Lodato, R.F.1    Maguire, H.C.2    Greene, M.I.3
  • 63
    • 0026793986 scopus 로고
    • Overexpression of Her-2/neu and its relationship with other prognostic factors changed during progression of in-situ to invasive breast cancer
    • Allred DC, Clark GM, Molina R et al. Overexpression of Her-2/neu and its relationship with other prognostic factors changed during progression of in-situ to invasive breast cancer. Hum Pathol 1992;23:974-979.
    • (1992) Hum Pathol , vol.23 , pp. 974-979
    • Allred, D.C.1    Clark, G.M.2    Molina, R.3
  • 64
    • 0027994342 scopus 로고
    • Mammographically-detected ductal in-situ carcinoma of the breast analyzed with a new classification
    • Zafrani B, Leroyer A, Fourquet A et al. Mammographically-detected ductal in-situ carcinoma of the breast analyzed with a new classification. Sem Diagn Pathol 1994;11:208-214.
    • (1994) Sem Diagn Pathol , vol.11 , pp. 208-214
    • Zafrani, B.1    Leroyer, A.2    Fourquet, A.3
  • 65
    • 0029365176 scopus 로고
    • Prognostic variables in invasive breast cancer: Contribution of comedo versus non-comedo in-situ component
    • Brower FT, Ahmed S, Tartter P et al. Prognostic variables in invasive breast cancer: Contribution of comedo versus non-comedo in-situ component. Ann Surg Oncol 1995;2:440-444.
    • (1995) Ann Surg Oncol , vol.2 , pp. 440-444
    • Brower, F.T.1    Ahmed, S.2    Tartter, P.3
  • 66
    • 0028952065 scopus 로고
    • Ductal carcinoma in-situ of the breast. Histologic categorization and its relationship to ploidy and immunohistochemical expression of hormone receptors, p53 and C erb B-2 protein
    • Leal CB, Schmitt FC, Bento NJ et al. Ductal carcinoma in-situ of the breast. Histologic categorization and its relationship to ploidy and immunohistochemical expression of hormone receptors, p53 and C erb B-2 protein. Cancer 1995;75:2123-2131.
    • (1995) Cancer , vol.75 , pp. 2123-2131
    • Leal, C.B.1    Schmitt, F.C.2    Bento, N.J.3
  • 67
    • 0029346984 scopus 로고
    • Ductal carcinoma in-situ: Assessment of necrosis in nuclear morphology and their association with biological markers
    • Bobrow WLG, Happerfield LC, Gregory WM et al. Ductal carcinoma in-situ: assessment of necrosis in nuclear morphology and their association with biological markers. J Pathol 1995;176:333-341.
    • (1995) J Pathol , vol.176 , pp. 333-341
    • Bobrow, W.L.G.1    Happerfield, L.C.2    Gregory, W.M.3
  • 68
    • 0028979423 scopus 로고
    • neu overexpression correlates with extent of disease in large cell ductal in situ carcinoma of the breast
    • DePotter CR, Schelhout AM, Verbeeck P et al. neu overexpression correlates with extent of disease in large cell ductal in situ carcinoma of the breast. Hum Pathol 1995;26:601-606.
    • (1995) Hum Pathol , vol.26 , pp. 601-606
    • DePotter, C.R.1    Schelhout, A.M.2    Verbeeck, P.3
  • 69
    • 0030025892 scopus 로고    scopus 로고
    • Differential distribution of erb B2 and pS2 proteins in ductal carcinoma in-situ of the breast
    • Inaji H, Koyama H, Motomura K et al. Differential distribution of erb B2 and pS2 proteins in ductal carcinoma in-situ of the breast. Breast Cancer Res Treat 1996;37:89-92.
    • (1996) Breast Cancer Res Treat , vol.37 , pp. 89-92
    • Inaji, H.1    Koyama, H.2    Motomura, K.3
  • 70
    • 0029864237 scopus 로고    scopus 로고
    • Biophenotypes of breast carcinoma in-situ defined by image analysis of biological parameters
    • Albonico G, Querzoli P, Ferretti S et al. Biophenotypes of breast carcinoma in-situ defined by image analysis of biological parameters. Pathol Res Pract 1996;192:117-123.
    • (1996) Pathol Res Pract , vol.192 , pp. 117-123
    • Albonico, G.1    Querzoli, P.2    Ferretti, S.3
  • 71
  • 72
    • 0030720490 scopus 로고    scopus 로고
    • Ductal carcinoma in-situ of the breast: Correlation between histologic classification and biologic markers
    • Moreno A, Lloveras B, Figueras A et al. Ductal carcinoma in-situ of the breast: Correlation between histologic classification and biologic markers. Mod Pathol 1997;10:1088-1092.
    • (1997) Mod Pathol , vol.10 , pp. 1088-1092
    • Moreno, A.1    Lloveras, B.2    Figueras, A.3
  • 73
    • 0030810732 scopus 로고    scopus 로고
    • Relationship of a new histological categorization of ductal carcinoma in-situ of the breast with size and the immunohistochemical expression of p53, C-erb B2, bcl2 and ki-67
    • Mack L, Kerkzelit N, Doig G et al. Relationship of a new histological categorization of ductal carcinoma in-situ of the breast with size and the immunohistochemical expression of p53, C-erb B2, bcl2 and ki-67. Hum Pathol 1997;28:974-979.
    • (1997) Hum Pathol , vol.28 , pp. 974-979
    • Mack, L.1    Kerkzelit, N.2    Doig, G.3
  • 74
    • 0025934515 scopus 로고
    • cerb B2 oncogene protein in in-situ and invasive lobular breast neoplasia
    • Porter PL, Garcia R, Moe R et al. cerb B2 oncogene protein in in-situ and invasive lobular breast neoplasia. Cancer 1991;68:331-334.
    • (1991) Cancer , vol.68 , pp. 331-334
    • Porter, P.L.1    Garcia, R.2    Moe, R.3
  • 75
    • 0026316781 scopus 로고
    • Expression of cerb B2 oncoprotein in mammary and extramammary Paget's disease
    • Wolber RA, DuPuis BA, Wick MR. Expression of cerb B2 oncoprotein in mammary and extramammary Paget's disease. Am J Clin Pathol 1991;96:243-247.
    • (1991) Am J Clin Pathol , vol.96 , pp. 243-247
    • Wolber, R.A.1    DuPuis, B.A.2    Wick, M.R.3
  • 76
    • 0026481642 scopus 로고
    • cerb B2 protein and neuroendocrine expression in intraductal carcinomas of the breast
    • Lilleng R, Hagmar BM, Nesland JM. cerb B2 protein and neuroendocrine expression in intraductal carcinomas of the breast. Mod Pathol 1992;5:41-47.
    • (1992) Mod Pathol , vol.5 , pp. 41-47
    • Lilleng, R.1    Hagmar, B.M.2    Nesland, J.M.3
  • 77
    • 0001390929 scopus 로고
    • Expression of erb B2 gene in the benign and proliferative breast tissue
    • Yeh I-T, Keykhah S, Selig AM et al. Expression of erb B2 gene in the benign and proliferative breast tissue. Surg Pathol 1993;5:109-120.
    • (1993) Surg Pathol , vol.5 , pp. 109-120
    • Yeh, I.-T.1    Keykhah, S.2    Selig, A.M.3
  • 78
    • 0025453481 scopus 로고
    • Distribution and patterns of staining of neu oncogene product in benign and malignant breast diseases
    • Hanna W, Kahn HJ, Andrulis I et al. Distribution and patterns of staining of neu oncogene product in benign and malignant breast diseases. Mod Pathol 1990;3:455-461.
    • (1990) Mod Pathol , vol.3 , pp. 455-461
    • Hanna, W.1    Kahn, H.J.2    Andrulis, I.3
  • 79
    • 0028303112 scopus 로고
    • Reduction of telomeric-linked cerb B2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical parameters
    • Odagiri E, Kanda N, Jibiki K et al. Reduction of telomeric-linked cerb B2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical parameters. Cancer 1994;73:2978-2984.
    • (1994) Cancer , vol.73 , pp. 2978-2984
    • Odagiri, E.1    Kanda, N.2    Jibiki, K.3
  • 80
    • 0028855402 scopus 로고
    • Prognostic factors for carcinoma of the male breast
    • Gattuso P, Reddy VB, Green LK et al. Prognostic factors for carcinoma of the male breast. Int J Surg Pathol 1995;2:199-206.
    • (1995) Int J Surg Pathol , vol.2 , pp. 199-206
    • Gattuso, P.1    Reddy, V.B.2    Green, L.K.3
  • 81
    • 0030029750 scopus 로고    scopus 로고
    • Male breast carcinoma: An evaluation of prognostic factors contributing to a poorer outcome
    • Joshi MG, Lee AK, Loda M et al. Male breast carcinoma: an evaluation of prognostic factors contributing to a poorer outcome. Cancer 1996;77:490-498.
    • (1996) Cancer , vol.77 , pp. 490-498
    • Joshi, M.G.1    Lee, A.K.2    Loda, M.3
  • 82
    • 0030838698 scopus 로고    scopus 로고
    • Male breast cancer: Pathological and immunohistochemical features
    • Willsher PC, Leach IH, Ellis IO et al. Male breast cancer: pathological and immunohistochemical features. Anticancer Res 1997;17:2335-2338.
    • (1997) Anticancer Res , vol.17 , pp. 2335-2338
    • Willsher, P.C.1    Leach, I.H.2    Ellis, I.O.3
  • 83
    • 0001549223 scopus 로고    scopus 로고
    • C-erb and p53 overexpression as predictors of survival in patients with male breast cancer
    • Bines J, GOSS B, Hussong J et al. C-erb and p53 overexpression as predictors of survival in patients with male breast cancer. Proc Ann Assoc Clin Oncol 1997;16:558a.
    • (1997) Proc Ann Assoc Clin Oncol , vol.16
    • Bines, J.1    Goss, B.2    Hussong, J.3
  • 84
    • 0030007221 scopus 로고    scopus 로고
    • Male breast cancer: Clinico-pathological features, immunocytochemical characteristics and prognosis
    • Bruce DM, Heyes SD, Payne S et al. Male breast cancer: clinico-pathological features, immunocytochemical characteristics and prognosis. Eur J Surg Oncol 1996;22:42-46.
    • (1996) Eur J Surg Oncol , vol.22 , pp. 42-46
    • Bruce, D.M.1    Heyes, S.D.2    Payne, S.3
  • 85
    • 0026955948 scopus 로고
    • Immunocytochemical characterization of male breast cancer
    • Dawson PJ, Paine TM, Wolman SR. Immunocytochemical characterization of male breast cancer. Mod Pathol 1992;5:621-625.
    • (1992) Mod Pathol , vol.5 , pp. 621-625
    • Dawson, P.J.1    Paine, T.M.2    Wolman, S.R.3
  • 86
    • 0026502860 scopus 로고
    • Relationship between C-ERBB 2 protein product expression and response to endocrine therapy in advanced breast cancer
    • Wright C, Nicholson S, Angus B et al. Relationship between C-ERBB 2 protein product expression and response to endocrine therapy in advanced breast cancer. Br J Cancer 1992;65:118-121.
    • (1992) Br J Cancer , vol.65 , pp. 118-121
    • Wright, C.1    Nicholson, S.2    Angus, B.3
  • 87
    • 0029005754 scopus 로고
    • Elevated serum C-erb B2 antigen levels and decreased response to hormone therapy of breast cancer
    • Leitzel K, Teramoto Y, Konrad K et al. Elevated serum C-erb B2 antigen levels and decreased response to hormone therapy of breast cancer. J Clin Oncol 1995;13:1129-1135.
    • (1995) J Clin Oncol , vol.13 , pp. 1129-1135
    • Leitzel, K.1    Teramoto, Y.2    Konrad, K.3
  • 88
    • 0029057890 scopus 로고
    • Oncogene amplification and prognosis in breast cancer: Relationship with systemic treatment
    • Berns EM, Foekens JA, vanStaveren IL et al. Oncogene amplification and prognosis in breast cancer: relationship with systemic treatment. Gene 1995;159:11-18.
    • (1995) Gene , vol.159 , pp. 11-18
    • Berns, E.M.1    Foekens, J.A.2    VanStaveren, I.L.3
  • 89
    • 0029591205 scopus 로고
    • C-erbB2 expression and benefit from adjuvant chemotherapy and radiotherapy of breast cancer
    • Stahl O, Sullivan S, Wingren S et al. C-erbB2 expression and benefit from adjuvant chemotherapy and radiotherapy of breast cancer. Eur J Cancer 1995;31:2185a-2190a.
    • (1995) Eur J Cancer , vol.31
    • Stahl, O.1    Sullivan, S.2    Wingren, S.3
  • 90
    • 0028861009 scopus 로고
    • Expression of ras p21, p53 and C-erb B2 in advanced breast cancer and response to line hormonal therapy
    • Archer SG, Eliopoulis SA, Spandidos D et al. Expression of ras p21, p53 and C-erb B2 in advanced breast cancer and response to line hormonal therapy. Br J Cancer 1995;72:1259-1266.
    • (1995) Br J Cancer , vol.72 , pp. 1259-1266
    • Archer, S.G.1    Eliopoulis, S.A.2    Spandidos, D.3
  • 91
    • 0029830451 scopus 로고    scopus 로고
    • Overexpression of cerbB2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms
    • Yu D, Liu B, Tan M et al. Overexpression of cerbB2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms. Oncogene 1996;13:1359-1365.
    • (1996) Oncogene , vol.13 , pp. 1359-1365
    • Yu, D.1    Liu, B.2    Tan, M.3
  • 92
    • 0029662337 scopus 로고    scopus 로고
    • CerbB2 overexpression decreases the benefit of adjuvant Tamoxifen in early-stage breast cancer without ancillary lymph node metastases
    • Carlomagno C, Perrone F, Gallo C et al. CerbB2 overexpression decreases the benefit of adjuvant Tamoxifen in early-stage breast cancer without ancillary lymph node metastases. J Clin Oncol 1996;14:2702-2708.
    • (1996) J Clin Oncol , vol.14 , pp. 2702-2708
    • Carlomagno, C.1    Perrone, F.2    Gallo, C.3
  • 93
    • 0030200381 scopus 로고    scopus 로고
    • Evaluation of HER-2/neu oncoprotein expression as a prognostic indicator of local recurrence in conservatively treated breast cancer: A case-control study
    • Haffty BG, Brown F, Carter D et al. Evaluation of HER-2/neu oncoprotein expression as a prognostic indicator of local recurrence in conservatively treated breast cancer: a case-control study. Int J Rad Oncol Biol Phys 1996;35:751-757.
    • (1996) Int J Rad Oncol Biol Phys , vol.35 , pp. 751-757
    • Haffty, B.G.1    Brown, F.2    Carter, D.3
  • 94
    • 0029920521 scopus 로고    scopus 로고
    • Plasma CerbB2 concentrations in relations to chemotherapy in breast cancer patients
    • Revillion F, Hebbar M, Boneterre J et al. Plasma CerbB2 concentrations in relations to chemotherapy in breast cancer patients. Eur J Cancer 1996;32:231a-234a.
    • (1996) Eur J Cancer , vol.32
    • Revillion, F.1    Hebbar, M.2    Boneterre, J.3
  • 95
    • 0030947407 scopus 로고    scopus 로고
    • HER-2 overexpression and paclitaxel sensitivity in breast cancer: Therapeutic implications
    • Baselga J, Seidman AD, Rosen PP et al. HER-2 overexpression and paclitaxel sensitivity in breast cancer: therapeutic implications. Oncology 1997;11:43-48.
    • (1997) Oncology , vol.11 , pp. 43-48
    • Baselga, J.1    Seidman, A.D.2    Rosen, P.P.3
  • 96
    • 0030870295 scopus 로고    scopus 로고
    • The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells
    • Pegram MD, Finn RS, Arzoo K et al. The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene 1997;15:537-547.
    • (1997) Oncogene , vol.15 , pp. 537-547
    • Pegram, M.D.1    Finn, R.S.2    Arzoo, K.3
  • 97
    • 0030860567 scopus 로고    scopus 로고
    • Expression of epidermal growth factor receptor and C-erb B2 during the development of tamoxifen resistance in human breast cancer
    • Newby JC, Johnston SRD, Smith IE et al. Expression of epidermal growth factor receptor and C-erb B2 during the development of tamoxifen resistance in human breast cancer. Clin Cancer Res 1997;3:1643-1651.
    • (1997) Clin Cancer Res , vol.3 , pp. 1643-1651
    • Newby, J.C.1    Johnston, S.R.D.2    Smith, I.E.3
  • 98
    • 0032032275 scopus 로고    scopus 로고
    • Predicting response to adjuvant and radiation therapy in patients with early stage breast carcinoma
    • Burke HB, Hoang A, Iglehart JD et al. Predicting response to adjuvant and radiation therapy in patients with early stage breast carcinoma. Cancer 1998;82:874-877.
    • (1998) Cancer , vol.82 , pp. 874-877
    • Burke, H.B.1    Hoang, A.2    Iglehart, J.D.3
  • 99
    • 0030757466 scopus 로고    scopus 로고
    • Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein
    • Yamauchi H, O'Neill A, Gelman R et al. Prediction of response to antiestrogen therapy in advanced breast cancer patients by pretreatment circulating levels of extracellular domain of the HER-2/c-neu protein. J Clin Oncol 1997;15:2518-2525.
    • (1997) J Clin Oncol , vol.15 , pp. 2518-2525
    • Yamauchi, H.1    O'Neill, A.2    Gelman, R.3
  • 100
    • 0031930148 scopus 로고    scopus 로고
    • HER-2 expression and response to tamoxifen in estrogen receptor-positive breast cancer a Southwest Oncology Group study
    • Elledge RM, Green S, Ciocca D et al. HER-2 expression and response to tamoxifen in estrogen receptor-positive breast cancer a Southwest Oncology Group study. Clin Cancer Res 1998;4:7-12.
    • (1998) Clin Cancer Res , vol.4 , pp. 7-12
    • Elledge, R.M.1    Green, S.2    Ciocca, D.3
  • 101
    • 0001240878 scopus 로고    scopus 로고
    • 20 year update of the Naples Gun trial of adjuvant breast cancer therapy: Eveidence of interaction between c-erb-B2 expression and tamoxifen efficacy
    • Bianco AR, De Laurentiis M, Carlomagno C et al. 20 year update of the Naples Gun trial of adjuvant breast cancer therapy: eveidence of interaction between c-erb-B2 expression and tamoxifen efficacy. Proc Am Soc Clin Oncol 1998;17:97a.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Bianco, A.R.1    De Laurentiis, M.2    Carlomagno, C.3
  • 102
    • 0000822847 scopus 로고    scopus 로고
    • Initial report of the SWOG biological correlative study of c-ERBB2 expression as a predictor of outcome in a trial comparing adjuvant CAF with Tamoxifen alone
    • Ravdin PM, Green S, Albain V et al. Initial report of the SWOG biological correlative study of c-ERBB2 expression as a predictor of outcome in a trial comparing adjuvant CAF with Tamoxifen alone. Proc Am Soc Clin Oncol 1998;17:97a.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Ravdin, P.M.1    Green, S.2    Albain, V.3
  • 103
    • 0027979311 scopus 로고
    • Elevated erb B-2 oncoprotein levels in preoperative and follow-up serum samples defined in aggressive course in patients with breast cancer
    • Isola JJ, Holli K, Oksa H et al. Elevated erb B-2 oncoprotein levels in preoperative and follow-up serum samples defined in aggressive course in patients with breast cancer. Cancer 1994;73:652-658.
    • (1994) Cancer , vol.73 , pp. 652-658
    • Isola, J.J.1    Holli, K.2    Oksa, H.3
  • 104
    • 0028059674 scopus 로고
    • Soluble c-erb B-2 fragments in serum correlates with disease stage and predicts more shortened survival in patients with early-stage and advanced breast cancer
    • Kandl H, Seymour L, Bezwoda WR. Soluble c-erb B-2 fragments in serum correlates with disease stage and predicts more shortened survival in patients with early-stage and advanced breast cancer. Br J Cancer 1994;70:739, 742.
    • (1994) Br J Cancer , vol.70 , pp. 739
    • Kandl, H.1    Seymour, L.2    Bezwoda, W.R.3
  • 105
    • 0028966695 scopus 로고
    • Measurement of C-erb B 2 proteins in sera from patients with carcinomas and in breast tumor tissue cytosols: Correlation with serum tumor markers and membrane-bound oncoproteins
    • Wu JT, Astill ME, Gagon SD et al. Measurement of C-erb B 2 proteins in sera from patients with carcinomas and in breast tumor tissue cytosols: correlation with serum tumor markers and membrane-bound oncoproteins. J Clin Lab Anal 1995;9:151-165.
    • (1995) J Clin Lab Anal , vol.9 , pp. 151-165
    • Wu, J.T.1    Astill, M.E.2    Gagon, S.D.3
  • 106
    • 0029001470 scopus 로고
    • Detection of C-erb B2 related proteins in sera from breast cancer patients. Relationship to ERBB2 gene amplification and Cerb B2 protein overexpression in tumour
    • Andersen TI, Paus E, Nesland JM et al. Detection of C-erb B2 related proteins in sera from breast cancer patients. Relationship to ERBB2 gene amplification and Cerb B2 protein overexpression in tumour. Acta Oncol 1995;34:499-504.
    • (1995) Acta Oncol , vol.34 , pp. 499-504
    • Andersen, T.I.1    Paus, E.2    Nesland, J.M.3
  • 107
    • 0030017945 scopus 로고    scopus 로고
    • Serial serum C-erbB-2 levels in patients with breast carcinoma
    • Volas GH, Leitzel K, Teramoto Y et al. Serial serum C-erbB-2 levels in patients with breast carcinoma. Cancer 1996;78:267-272.
    • (1996) Cancer , vol.78 , pp. 267-272
    • Volas, G.H.1    Leitzel, K.2    Teramoto, Y.3
  • 108
    • 10144247242 scopus 로고    scopus 로고
    • Utility of cerbB2 in tissue and in serum in the early diagnosis of recurrence in breast cancer patients: Comparison with carcinoembryonic antigen and CA15.3
    • Molina R, Jo J, Vanon G et al. Utility of cerbB2 in tissue and in serum in the early diagnosis of recurrence in breast cancer patients: comparison with carcinoembryonic antigen and CA15.3. Br J Cancer 1996;74:1126-1131.
    • (1996) Br J Cancer , vol.74 , pp. 1126-1131
    • Molina, R.1    Jo, J.2    Vanon, G.3
  • 109
    • 0029837782 scopus 로고    scopus 로고
    • Prognostic significance of serum CerbB2 protein in breast cancer patients
    • Willsher PC, Beaver J, Pinder S et al. Prognostic significance of serum CerbB2 protein in breast cancer patients. Breast Cancer Res Treat 1996;40:251-255.
    • (1996) Breast Cancer Res Treat , vol.40 , pp. 251-255
    • Willsher, P.C.1    Beaver, J.2    Pinder, S.3
  • 110
    • 0031048153 scopus 로고    scopus 로고
    • Influence of circulating C-erbB-2 serum protein on response to adjuvant chemotherapy in node-positive breast cancer patients
    • Fehm T, Maimonis P, Wetz S et al. Influence of circulating C-erbB-2 serum protein on response to adjuvant chemotherapy in node-positive breast cancer patients. Breast Cancer Res Treat 1997;43:87-95.
    • (1997) Breast Cancer Res Treat , vol.43 , pp. 87-95
    • Fehm, T.1    Maimonis, P.2    Wetz, S.3
  • 111
    • 0030801178 scopus 로고    scopus 로고
    • Tissue in serum CerbB2 and tissue EGFR in breast carcinoma: Three years follow-up
    • Mansour OA, Zekri AR, Harvey J et al. Tissue in serum CerbB2 and tissue EGFR in breast carcinoma: three years follow-up. Ami Cancer Res 1997;17:3101-3106.
    • (1997) Ami Cancer Res , vol.17 , pp. 3101-3106
    • Mansour, O.A.1    Zekri, A.R.2    Harvey, J.3
  • 112
    • 0025804023 scopus 로고
    • Monoclonal antibody therapy of human cancer: Taking the Her-2 proto-oncogene to the clinic
    • Shepard HM, Lewis GD, Sarup JC et al. Monoclonal antibody therapy of human cancer: taking the Her-2 proto-oncogene to the clinic. J Clin Immunol 1991;11:117-127.
    • (1991) J Clin Immunol , vol.11 , pp. 117-127
    • Shepard, H.M.1    Lewis, G.D.2    Sarup, J.C.3
  • 113
    • 0029118536 scopus 로고
    • Suppressed transformation and induced differentiation of Her-2/neu - Overexpressing breast cancer cells by emodin
    • Zhang L, Chang C, Bacus SS et al. Suppressed transformation and induced differentiation of Her-2/neu - overexpressing breast cancer cells by emodin. Cancer Res 1995;55:3890-3896.
    • (1995) Cancer Res , vol.55 , pp. 3890-3896
    • Zhang, L.1    Chang, C.2    Bacus, S.S.3
  • 114
    • 0029095589 scopus 로고
    • Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu
    • Valone FH, Kaufman PA, Guyre PM et al. Phase Ia/Ib trial of bispecific antibody MDX-210 in patients with advanced breast or ovarian cancer that overexpresses the proto-oncogene HER-2/neu. J Clin Oncol 1995;13:2281-2292.
    • (1995) J Clin Oncol , vol.13 , pp. 2281-2292
    • Valone, F.H.1    Kaufman, P.A.2    Guyre, P.M.3
  • 115
    • 0029679725 scopus 로고    scopus 로고
    • Effectiveness of an Adriamycin immunoconjugate that recognizes the CerbB2 product on breast cancer cell lines
    • Jinno H, Ueda M, Enomoto K et al. Effectiveness of an Adriamycin immunoconjugate that recognizes the CerbB2 product on breast cancer cell lines. Surg Today 1996;26:501-507.
    • (1996) Surg Today , vol.26 , pp. 501-507
    • Jinno, H.1    Ueda, M.2    Enomoto, K.3
  • 116
    • 0029991439 scopus 로고    scopus 로고
    • Phase II study of weekly intravenous recombinant humanized anti p 185 Her-2 monoclonal antibody in patients with Her-2/neu overexpressing metastatic breast cancer
    • Baselga J, Tripathy D, Mendelsohn J et al. Phase II study of weekly intravenous recombinant humanized anti p 185 Her-2 monoclonal antibody in patients with Her-2/neu overexpressing metastatic breast cancer. J Clin Oncol 1996;14:737-744.
    • (1996) J Clin Oncol , vol.14 , pp. 737-744
    • Baselga, J.1    Tripathy, D.2    Mendelsohn, J.3
  • 117
    • 0029886613 scopus 로고    scopus 로고
    • Inhibition of erbB2 positive breast cancer cell growth by erbB2 antisense oligonucleotides
    • Liu X, Pogo BG. Inhibition of erbB2 positive breast cancer cell growth by erbB2 antisense oligonucleotides. Antisense Nucleic Acid Drug Devel 1996;6:9-16.
    • (1996) Antisense Nucleic Acid Drug Devel , vol.6 , pp. 9-16
    • Liu, X.1    Pogo, B.G.2
  • 118
    • 0030935529 scopus 로고    scopus 로고
    • An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2
    • Wright M, Grim J, Deshane J et al. An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2. Gene Ther 1997;4:317-322.
    • (1997) Gene Ther , vol.4 , pp. 317-322
    • Wright, M.1    Grim, J.2    Deshane, J.3
  • 119
    • 0031053094 scopus 로고    scopus 로고
    • The clinical studies with Fc (Gamma) R by specific antibodies and granulocyte colony-stimulating factor-primed neutrophils as effector cells against HER-2/neu overexpression in breast cancer
    • Heijnen IA, Buhring HJ, Deo YN et al. The clinical studies with Fc (Gamma) R by specific antibodies and granulocyte colony-stimulating factor-primed neutrophils as effector cells against HER-2/neu overexpression in breast cancer. Cancer Res 1997;57:696-701.
    • (1997) Cancer Res , vol.57 , pp. 696-701
    • Heijnen, I.A.1    Buhring, H.J.2    Deo, Y.N.3
  • 120
    • 0031015394 scopus 로고    scopus 로고
    • Enhanced anti-proliferative activity of the combination of tamoxifen plus HER-2-neu antibody
    • Witters LM, Kumar R, Chinchilli ZM et al. Enhanced anti-proliferative activity of the combination of tamoxifen plus HER-2-neu antibody. Breast Cancer Res Treat 1997;42:1-5.
    • (1997) Breast Cancer Res Treat , vol.42 , pp. 1-5
    • Witters, L.M.1    Kumar, R.2    Chinchilli, Z.M.3
  • 121
    • 0000905158 scopus 로고    scopus 로고
    • Efficacy and safety of Herceptin® (humanized anti-human HER-2 antibody) as a single agent in 222 women with HER2 overexpression who relapsed following chemotherapy for metastatic breast cancer
    • Cobleigh MA, Vogel CL, Tripathy NJ et al. Efficacy and safety of Herceptin® (humanized anti-human HER-2 antibody) as a single agent in 222 women with HER2 overexpression who relapsed following chemotherapy for metastatic breast cancer. Proc Am Soc Clin Oncol 1998;17:97a.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, N.J.3
  • 122
    • 0000405942 scopus 로고    scopus 로고
    • Addition of Herceptin® (humanized anti HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer markedly increases anticancer activity: A randomized, multinational controlled phase III trial
    • Slamon D, Leyland-Jones B, Shak S et al. Addition of Herceptin® (humanized anti HER2 antibody) to first line chemotherapy for HER2 overexpressing metastatic breast cancer markedly increases anticancer activity: a randomized, multinational controlled phase III trial. Proc Am Soc Clin Oncol 1998;17:98a.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Slamon, D.1    Leyland-Jones, B.2    Shak, S.3
  • 123
    • 0032520044 scopus 로고    scopus 로고
    • Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes
    • Brossart P, Stuhler J, Flad P et al. Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes. Cancer Res 1998;58:732-736.
    • (1998) Cancer Res , vol.58 , pp. 732-736
    • Brossart, P.1    Stuhler, J.2    Flad, P.3
  • 124
    • 0003237802 scopus 로고    scopus 로고
    • HER-2/neu peptide vaccines elicit T cell immunity to the HER-2/neu protein in patients with breast and ovarian cancer
    • Disis ML, Grabstein KH, Cheaver MA, HER-2/neu peptide vaccines elicit T cell immunity to the HER-2/neu protein in patients with breast and ovarian cancer. Proc Am Soc Clin Oncol 1998;17:97a.
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Disis, M.L.1    Grabstein, K.H.2    Cheaver, M.A.3
  • 125
    • 0028690586 scopus 로고
    • Clinicoradioimmunolocalization with a rat monoclonal antibody directed against C-erb B2
    • Allan SM, Dean CJ, Eccles S et al. Clinicoradioimmunolocalization with a rat monoclonal antibody directed against C-erb B2. Cell Biophys 1994;24:93-98.
    • (1994) Cell Biophys , vol.24 , pp. 93-98
    • Allan, S.M.1    Dean, C.J.2    Eccles, S.3


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