메뉴 건너뛰기




Volumn 59, Issue 22, 1999, Pages 5808-5814

Pten suppresses breast cancer cell growth by phosphatase activity- dependent arrest followed by cell death

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATASE; PROTEIN PHOSPHATASE PTEN; UNCLASSIFIED DRUG; WORTMANNIN;

EID: 0033571477     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (234)

References (51)
  • 2
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor B
    • Li, D-M., and Sun, H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor B. Cancer Res., 57: 2124-2129, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2124-2129
    • Li, D.-M.1    Sun, H.2
  • 4
    • 0002425663 scopus 로고    scopus 로고
    • Cowden syndrome
    • B. Vogelstein and K. W. Kinzler (eds.). New York: McGraw-Hill
    • Eng, C., and Parsons, R. Cowden syndrome. In: B. Vogelstein and K. W. Kinzler (eds.), The Genetic Basis of Human Cancer, pp. 519-526. New York: McGraw-Hill, 1998.
    • (1998) The Genetic Basis of Human Cancer , pp. 519-526
    • Eng, C.1    Parsons, R.2
  • 5
    • 0031883606 scopus 로고    scopus 로고
    • Genetics of Cowden syndrome: Through the looking glass of oncology
    • Eng, C. Genetics of Cowden syndrome: through the looking glass of oncology. Int. J. Oncol., 12: 701-710, 1998.
    • (1998) Int. J. Oncol. , vol.12 , pp. 701-710
    • Eng, C.1
  • 9
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • Di Cristofano, A., Pesce, B., Cordon-Cardo, C., and Pandolfi, P. P. Pten is essential for embryonic development and tumour suppression. Nat. Genet., 19: 348-355, 1998.
    • (1998) Nat. Genet. , vol.19 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4
  • 12
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger phosphoinositol 3,4,5-triphosphate
    • Maehama, T., and Dixon, J. E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger phosphoinositol 3,4,5-triphosphate. J. Biol. Chem., 273: 13375-13378, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 13
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • Washington DC
    • Tamura, M., Gu, J., Matsumoto, K., Aota, S-i., Parsons, R., and Yamada, K. M. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science (Washington DC), 280: 1614-1617, 1998.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.-I.4    Parsons, R.5    Yamada, K.M.6
  • 14
    • 0032431028 scopus 로고    scopus 로고
    • PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
    • Li, D. M., and Sun, H. PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells. Proc. Natl. Acad. Sci. USA, 95: 15406-15411, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15406-15411
    • Li, D.M.1    Sun, H.2
  • 15
    • 0032534963 scopus 로고    scopus 로고
    • The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene
    • Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., and Parsons, R. The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Res., 58: 5667-5672, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 5667-5672
    • Li, J.1    Simpson, L.2    Takahashi, M.3    Miliaresis, C.4    Myers, M.P.5    Tonks, N.6    Parsons, R.7
  • 16
    • 3643119742 scopus 로고    scopus 로고
    • The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells
    • Furnari, F. B., SuHuang, H-J., and Cavanee, W. K. The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells. Cancer Res., 58: 5002-5008, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 5002-5008
    • Furnari, F.B.1    Suhuang, H.-J.2    Cavanee, W.K.3
  • 21
    • 0031265032 scopus 로고    scopus 로고
    • Current data on the role of the APC protein in the origin of colorectal cancer
    • Phila.
    • Bonneton, C., Larue, L., and Thiery, J. P. Current data on the role of the APC protein in the origin of colorectal cancer. Bull. Cancer (Phila.), 84: 1053-1060, 1997.
    • (1997) Bull. Cancer , vol.84 , pp. 1053-1060
    • Bonneton, C.1    Larue, L.2    Thiery, J.P.3
  • 24
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen, M., and Bujard, H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA, 89: 5547-5551, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 25
    • 0032567908 scopus 로고    scopus 로고
    • Overexpression of the transmembrane tyrosine phosphatase LAR activates the caspase pathway and induces apoptosis
    • Weng, L. P., Yuan, J., and Yu, Q. Overexpression of the transmembrane tyrosine phosphatase LAR activates the caspase pathway and induces apoptosis. Curr. Biol., 8: 247-256, 1998.
    • (1998) Curr. Biol. , vol.8 , pp. 247-256
    • Weng, L.P.1    Yuan, J.2    Yu, Q.3
  • 29
    • 0029022369 scopus 로고
    • Transcriptional activation by tetracyclines in mammalian cells
    • Washington DC
    • Gossen, M., Freundlieb, S., Bender, G., Muller, G., Hillen, W., and Bujard, H. Transcriptional activation by tetracyclines in mammalian cells. Science (Washington DC), 268: 1756-1769, 1995.
    • (1995) Science , vol.268 , pp. 1756-1769
    • Gossen, M.1    Freundlieb, S.2    Bender, G.3    Muller, G.4    Hillen, W.5    Bujard, H.6
  • 32
    • 0031936353 scopus 로고    scopus 로고
    • Ras signalling and apoptosis
    • Downward, J. Ras signalling and apoptosis. Curr. Opin. Genet. Dev., 8: 49-54, 1998.
    • (1998) Curr. Opin. Genet. Dev. , vol.8 , pp. 49-54
    • Downward, J.1
  • 33
    • 0033563157 scopus 로고    scopus 로고
    • Adenovirus-mediated gene entry of MMAC1/PTEN to glioblastoma inhibits S phase entry by the recruitment of p27Kip2 and cyclin E/CDK2 complexes
    • Cheney, I. W., Neuteboom, S. T. C., Vaillancourt, M-T., Ramachandra, M., and Bookstein, R. Adenovirus-mediated gene entry of MMAC1/PTEN to glioblastoma inhibits S phase entry by the recruitment of p27Kip2 and cyclin E/CDK2 complexes. Cancer Res., 59: 2318-2323, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2318-2323
    • Cheney, I.W.1    Neuteboom, S.T.C.2    Vaillancourt, M.-T.3    Ramachandra, M.4    Bookstein, R.5
  • 38
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase and Akt
    • Kulik, G., Klippel, A., and Weber, M. J. Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase and Akt. Mol. Cell. Biol., 17: 1595-1606, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 39
    • 0028963084 scopus 로고
    • Requirement for phosphatidylinositol 3-kinase in the prevention of apoptosis by nerve growth factor
    • Washington DC
    • Yao, R., and Cooper, G. M. Requirement for phosphatidylinositol 3-kinase in the prevention of apoptosis by nerve growth factor. Science (Washington DC), 267: 2003-2006, 1995.
    • (1995) Science , vol.267 , pp. 2003-2006
    • Yao, R.1    Cooper, G.M.2
  • 40
    • 0030728479 scopus 로고    scopus 로고
    • Growth suppression of glioma cells by PTEN requires a functional catalytic domain
    • Fumari, F. B., Lin, H., Huang, H-J. S., and Cavanee, W. K. Growth suppression of glioma cells by PTEN requires a functional catalytic domain. Proc. Natl. Acad. Sci. USA, 94: 12479-12484, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12479-12484
    • Fumari, F.B.1    Lin, H.2    Huang, H.-J.S.3    Cavanee, W.K.4
  • 42
    • 0032911889 scopus 로고    scopus 로고
    • Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p17(S6K)-independent signaling in growth factor stimulated NIH 3T3 fibroblasts
    • Takuwa, N., Fukui, Y., and Takuwawa, Y. Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p17(S6K)-independent signaling in growth factor stimulated NIH 3T3 fibroblasts. Mol. Cell. Biol., 19: 1346-1358, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1346-1358
    • Takuwa, N.1    Fukui, Y.2    Takuwawa, Y.3
  • 43
    • 0030666921 scopus 로고    scopus 로고
    • Mitogenic signaling of insulin-like growth factor I in human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase
    • Dufourny, B., Ablas, J., van Teeffelen, H. A., van Schaik, F. M., van den Burg, B., Steenbergh, P. H., and Sussenbach, J. S. Mitogenic signaling of insulin-like growth factor I in human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J. Biol. Chem., 272: 31163-31171, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31163-31171
    • Dufourny, B.1    Ablas, J.2    Van Teeffelen, H.A.3    Van Schaik, F.M.4    Van Den Burg, B.5    Steenbergh, P.H.6    Sussenbach, J.S.7
  • 44
    • 0032571084 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase inhibitors block aortic smooth muscle cell proliferation in mid-late G1 phase: Effect on cyclin-dependent kinase 2 and the inhibitory protein p27KIP1
    • Bacqueville, D., Casagrande, F., Perret, B., Chap, H., Darbon, J. M., and Breton-Douillon, M. Phosphatidylinositol 3-kinase inhibitors block aortic smooth muscle cell proliferation in mid-late G1 phase: effect on cyclin-dependent kinase 2 and the inhibitory protein p27KIP1. Biochem. Biophys. Res. Commun., 244: 630-636, 1998.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 630-636
    • Bacqueville, D.1    Casagrande, F.2    Perret, B.3    Chap, H.4    Darbon, J.M.5    Breton-Douillon, M.6
  • 45
    • 0030769913 scopus 로고    scopus 로고
    • Phosphatidylinositol 3 kinase-independent p70 S6 kinase activation by fibroblast growth factor receptor-1 is important for proliferation but not differentiation of endothelial cells
    • Kanda, S., Hodgkin, M. N., Woodfield, R. J., Wkelam, M. J., Thomas, G., and Claesson-Welsh, L. Phosphatidylinositol 3 kinase-independent p70 S6 kinase activation by fibroblast growth factor receptor-1 is important for proliferation but not differentiation of endothelial cells. J. Biol. Chem., 272: 23347-23353, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23347-23353
    • Kanda, S.1    Hodgkin, M.N.2    Woodfield, R.J.3    Wkelam, M.J.4    Thomas, G.5    Claesson-Welsh, L.6
  • 46
    • 0027336002 scopus 로고
    • p70sk6 function is essential for G1 progression
    • Lond.
    • Lane, H. A., Fernandez, A., Lamb, N. J., and Thomas, G. p70sk6 function is essential for G1 progression. Nature (Lond.), 363: 170-172, 1993.
    • (1993) Nature , vol.363 , pp. 170-172
    • Lane, H.A.1    Fernandez, A.2    Lamb, N.J.3    Thomas, G.4
  • 47
    • 0030890933 scopus 로고    scopus 로고
    • Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase
    • Ahmed, N. N., Grimes, H. L., Bellacosa, A., Chan, T. O., and Tsichlis, P. N. Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl. Acad. Sci. USA, 94: 3627-3632, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3627-3632
    • Ahmed, N.N.1    Grimes, H.L.2    Bellacosa, A.3    Chan, T.O.4    Tsichlis, P.N.5
  • 50
    • 0031950790 scopus 로고    scopus 로고
    • BRCA1: A review of structure and putative function
    • Paterson, J. W. BRCA1: a review of structure and putative function. Dis. Markers, 13: 261-274, 1998.
    • (1998) Dis. Markers , vol.13 , pp. 261-274
    • Paterson, J.W.1
  • 51
    • 0029948779 scopus 로고    scopus 로고
    • Induction of apoptosis by the tumor suppressor protein BRCA1
    • Shao, N., Chai, Y. L., Shyam, E., Reddy, P., and Rao, V. N. Induction of apoptosis by the tumor suppressor protein BRCA1. Oncogene, 13: 1-7, 1996.
    • (1996) Oncogene , vol.13 , pp. 1-7
    • Shao, N.1    Chai, Y.L.2    Shyam, E.3    Reddy, P.4    Rao, V.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.