-
11
-
-
0031815596
-
Toward an understanding of the functional complexity of the E2F and retinoblastoma families
-
(1998)
Cell Growth Differ.
, vol.9
, pp. 585-593
-
-
Nevins, J.R.1
-
14
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting histone deacetylase
-
(1998)
Nature (Lond.)
, vol.391
, pp. 601-605
-
-
Magnaghi, J.L.1
Groisman, R.2
Naguibneva, I.3
Robin, P.4
Lorain, S.5
Le, V.J.6
Troalen, F.7
Trouche, D.8
Harel, B.A.9
-
15
-
-
0034737290
-
Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSW1/SNF and Rb-hSW1/SNF
-
(2000)
Cell
, vol.101
, pp. 79-89
-
-
Zhang, H.S.1
Gavin, M.2
Dahiya, A.3
Postigo, A.A.4
Ma, D.5
Luo, R.X.6
Harbour, W.J.7
Dean, D.C.8
-
17
-
-
0025734356
-
Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family
-
(1991)
Cell
, vol.66
, pp. 1217-1228
-
-
Koff, A.1
Cross, F.2
Fisher, A.3
Schumacher, J.4
Leguellec, K.5
Philippe, M.6
Roberts, J.M.7
-
20
-
-
0026649165
-
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle
-
(1992)
Science (Washington DC)
, vol.257
, pp. 1689-1694
-
-
Koff, A.1
Giordano, A.2
Desai, D.3
Yamashita, K.4
Harper, J.W.5
Elledge, S.6
Nishimoto, T.7
Morgan, D.O.8
Franza, B.R.9
Roberts, J.M.10
-
24
-
-
12644284504
-
The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2
-
(1996)
EMBO J.
, vol.15
, pp. 7060-7069
-
-
Kitagawa, M.1
Higashi, H.2
Jung, H.K.3
Suzuki-Takahashi, I.4
Ikeda, M.5
Tamai, K.6
Kato, J.7
Segawa, K.8
Yoshida, E.9
Nishimura, S.10
Taya, Y.11
-
27
-
-
0025831974
-
Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes
-
(1991)
Cell
, vol.66
, pp. 731-742
-
-
Fang, F.1
Newport, J.W.2
-
29
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, E.8
Kinzler, K.W.9
Vogelstein, B.10
-
32
-
-
0028179669
-
Kip1, a cyclin-cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
-
(1994)
Genes Dev.
, vol.8
, pp. 9-22
-
-
Polyak, K.1
Kato, J.-Y.2
Solomon, M.J.3
Sherr, C.J.4
Massagué, J.5
Roberts, J.M.6
Koff, A.7
-
33
-
-
0028176483
-
Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.-H.2
Erdjument-Bromage, H.3
Koff, A.4
Roberts, J.M.5
Tempst, P.6
Massagué, J.7
-
34
-
-
0028363519
-
p27, a novel inhibitor of G1 cyclin/cdk protein kinase activity, is related to p21
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Toyoshima, H.1
Hunter, T.2
-
36
-
-
0028988159
-
CIP1 cdk inhibitor family, is a candidate tumor suppressor gene
-
(1995)
Genes Dev.
, vol.9
, pp. 650-662
-
-
Matsuoka, S.1
Edwards, M.2
Bai, C.3
Parker, S.4
Zhang, P.5
Baldini, A.6
Harper, J.W.7
Elledge, S.J.8
-
38
-
-
9044232147
-
Formation of p27-CDK complexes during the human mitotic cell cycle
-
(1996)
Cell Growth Differ.
, vol.7
, pp. 135-146
-
-
Soos, T.J.1
Kiyokawa, H.2
Yan, J.S.3
Rubin, M.S.4
Giordano, A.5
DeBlasio, A.6
Bottega, S.7
Wong, B.8
Mendelsohn, J.9
Koff, A.10
-
40
-
-
0030973878
-
New functional activities for the p21 family of CDK inhibitors
-
(1997)
Genes Dev.
, vol.11
, pp. 847-862
-
-
LaBaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
Slingerland, J.M.4
Sandhu, C.5
Chou, H.S.6
Fattaey, A.7
Harlow, E.8
-
43
-
-
0029024015
-
Role of the ubiquitin-proteosome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
-
(1995)
Science (Washington DC)
, vol.269
, pp. 682-685
-
-
Pagano, M.1
Tam, S.W.2
Theodoras, A.M.3
Beer-Romano, P.4
Dal Sal, G.5
Chau, V.6
Yew, P.R.7
Draetta, G.F.8
Rolfe, M.9
-
49
-
-
16944363001
-
Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer
-
(1997)
Nat. Med.
, vol.3
, pp. 227-230
-
-
Catzavelos, C.1
Bhattacharya, N.2
Ung, Y.C.3
Wilson, J.A.4
Roncari, L.5
Sandhu, C.6
Shaw, P.7
Yeger, H.8
Morava-Protzner, I.9
Kapusta, L.10
Franssen, E.11
Pritchard, K.I.12
Slingerland, J.M.13
-
50
-
-
0031048716
-
Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
-
(1997)
Nat. Med.
, vol.3
, pp. 222-225
-
-
Porter, P.L.1
Malone, K.E.2
Heagerty, P.J.3
Alexander, G.M.4
Gatti, L.A.5
Firpo, F.J.6
Daling, J.R.7
Roberts, J.M.8
-
52
-
-
0028582034
-
INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
-
(1994)
Genes Dev.
, vol.8
, pp. 2939-2952
-
-
Guan, K.-L.1
Jenkins, C.W.2
Li, Y.3
Nichols, M.A.4
Wu, X.5
O'Keefe, C.L.6
Matera, A.G.7
Xiong, Y.8
-
53
-
-
0029054399
-
Retinoblastoma protein-dependent cell cycle inhibition by the tumor suppressor p16
-
(1995)
Nature (Lond.)
, vol.375
, pp. 503-506
-
-
Lukas, J.1
Parry, D.2
Aagaard, L.3
Mann, D.J.4
Bartkova, J.5
Strauss, M.6
Peters, G.7
Bartek, J.8
-
59
-
-
0028121279
-
A cell cycle regulator involved in genesis of many tumor types
-
(1994)
Science (Washington DC)
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, Q.4
Harshman, K.5
Tavtigian, S.V.6
Stockert, E.7
Day III, R.S.8
Johnson, B.E.9
Skolnick, M.H.10
-
62
-
-
0032530112
-
Kip1 mediate two separate pathways to collaboratively suppress pituitary tumorigenesis
-
(1998)
Genes Dev.
, vol.12
, pp. 2899-2911
-
-
Franklin, D.S.1
Godfrey, V.L.2
Lee, H.3
Kovalev, G.I.4
Schoonhoven, R.5
Chen-Kiang, S.6
Su, L.7
Xiong, Y.8
-
66
-
-
0030728468
-
ARF
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
68
-
-
0029060657
-
Complex structure and regulation of the p16(MTS1) locus
-
(1995)
Cancer Res.
, vol.55
, pp. 2988-2994
-
-
Stone, S.1
Jiang, P.2
Dayananth, P.3
Tavtigian, S.V.4
Katcher, H.5
Parry, D.6
Peters, G.7
Kamb, A.8
-
73
-
-
0020520517
-
Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture
-
(1983)
Nature (Lond.)
, vol.304
, pp. 602-606
-
-
Ruley, H.E.1
-
74
-
-
0026303190
-
p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
-
(1991)
Genes Dev.
, vol.5
, pp. 2375-2385
-
-
Harvey, D.M.1
Levine, A.J.2
-
76
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
78
-
-
0032169516
-
ARF, participates in a regulatory feedback loop with p53 and MDM2
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.1
Bates, S.A.2
James, M.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Hara, E.8
Vousden, K.H.9
Peters, G.10
-
79
-
-
0032549704
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liégeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.-W.10
Cordon-Cardo, C.11
DePinho, R.12
-
80
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppressor pathways
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
86
-
-
0033521621
-
ARF with Mdm2 inhibits ubiquitin ligase activity of MDM2 for tumor suppressor p53
-
(1999)
EMBO J.
, vol.18
, pp. 22-27
-
-
Honda, R.1
Yasuda, H.2
-
88
-
-
0033000482
-
Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53
-
(1999)
Mol. Cell
, vol.3
, pp. 579-591
-
-
Zhang, Y.1
Xiong, Y.2
-
92
-
-
0030825813
-
p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding
-
(1997)
Oncogene
, vol.15
, pp. 1179-1189
-
-
Midgley, C.A.1
Lane, D.P.2
-
94
-
-
0032146795
-
ARF tumor suppressor
-
(1998)
Genes Dev.
, vol.12
, pp. 2434-2442
-
-
De Stanchina, E.1
McCurrach, M.E.2
Zindy, F.3
Shieh, S.Y.4
Ferbeyre, G.5
Samuelson, A.V.6
Prives, C.7
Roussel, M.F.8
Sherr, C.J.9
Lowe, S.W.10
-
99
-
-
0022380768
-
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
-
(1985)
Nature (Lond.)
, vol.318
, pp. 533-538
-
-
Adams, J.M.1
Harris, A.W.2
Pinkert, C.A.3
Corcoran, L.M.4
Alexander, W.S.5
Cory, S.6
Palmiter, R.D.7
Brinster, R.L.8
-
105
-
-
0032961828
-
MDM2 suppresses p73 function without promoting p73 degradation
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3257-3266
-
-
Zeng, X.1
Chen, L.2
Jost, C.A.3
Maya, R.4
Keller, D.5
Wang, X.6
Kaelin W.G., Jr.7
Oren, M.8
Chen, J.9
Lu, H.10
-
108
-
-
0032185124
-
p300/MDM2 complexes participate in MDM2-mediated p53 degradation
-
(1998)
Mol. Cell
, vol.2
, pp. 405-415
-
-
Grossman, S.R.1
Perez Kung, A.L.2
Joseph, M.3
Mansur, C.4
Xiao, Z.X.5
Kumar, S.6
Howley, P.M.7
Livingston, D.M.8
-
114
-
-
0033551066
-
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4221-4223
-
-
Chen, Y.N.1
Sharma, S.K.2
Ramsay, T.M.3
Jiang, L.4
Martin, M.S.5
Baker, K.6
Adams, P.D.7
Bair, K.W.8
Kaelin W.G., Jr.9
-
115
-
-
0034594978
-
A ribonucleotide reductase gene involved in p53-dependent cell-cycle checkpoint for DNA damage
-
(2000)
Nature (Lond.)
, vol.404
, pp. 42-49
-
-
Tanaka, H.1
Arakawa, H.2
Yamaguchi, T.3
Shiraishi, K.4
Fukuda, S.5
Matsui, K.6
Takei, Y.7
Nakamura, Y.8
-
117
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
(1999)
J. Clin. Investig.
, vol.104
, pp. 155-162
-
-
Ashkenazi, A.1
Pai, R.C.2
Fong, S.3
Leung, S.4
Lawrence, D.A.5
Marsters, S.A.6
Blackie, C.7
Chang, L.8
McMurtrey, A.E.9
Hebert, A.10
DeForge, L.11
Koumenis, I.L.12
Lewis, D.13
Harris, L.14
Bussiere, J.15
Keoppen, H.16
Shahrokh, Z.17
Schwall, R.H.18
|