메뉴 건너뛰기




Volumn 11, Issue 17, 2011, Pages 2192-2209

Disease-related changes in TRPV1 expression and its implications for drug development

Author keywords

Inflammatory mediators; Nociceptive ion channels; Nociceptors; Pain; Trpv1

Indexed keywords

1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL]UREA; 1 (5 ISOQUINOLINYL) 3 [4 (TRIFLUOROMETHYL)BENZYL]UREA; 12 HYDROXYICOSATETRAENOIC ACID; 2 [6 (2 ACETYLAMINO 1,3 BENZOTHIAZOL 4 YLOXY) 4 PYRIMIDINYL] 5 (TRIFLUOROMETHYL)PHENYLCARBAMIC ACID TERT BUTYL ESTER; 3 [2 (1 PIPERIDINYL) 6 (TRIFLUOROMETHYL) 3 PYRIDINYL] N (5,6,7,8 TETRAHYDRO 7 HYDROXY 1 NAPHTHYL)ACRYLAMIDE; 4 [3 (TRIFLUOROMETHYL) 2 PYRIDINYL] N [5 (TRIFLUOROMETHYL) 2 PYRIDINYL] 1 PIPERAZINECARBOXAMIDE; 4 CHLORO N (3 METHOXYPHENYL)CINNAMAMIDE; A 784168; A 795614; AMG 8562; ANANDAMIDE; CALCITONIN GENE RELATED PEPTIDE; CAPSAICIN; CAPSAZEPINE; GRC 6211; IODORESINIFERATOXIN; JYL 1421; METHANANDAMIDE; MK 2295; N (1,4 BENZODIOXAN 6 YL) 3 (4 TERT BUTYLPHENYL)ACRYLAMIDE; N (4 TERT BUTYLPHENYL) 4 (3 CHLORO 2 PYRIDINYL) 1 PIPERAZINECARBOXAMIDE; N [4 [6 [4 (TRIFLUOROMETHYL)PHENYL] 4 PYRIMIDINYLOXY]BENZOTHIAZOL 2 YL]ACETAMIDE; N OLEOYLETHANOLAMINE; NDG 8243; RESINIFERATOXIN; SA 13353; SCATTER FACTOR; SUBSTANCE P; TRANSIENT RECEPTOR POTENTIAL VANILLOID 1 AGONIST; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 1 ANTAGONIST; VANILLOID RECEPTOR AGONIST;

EID: 80052227817     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802611796904834     Document Type: Review
Times cited : (26)

References (331)
  • 1
    • 0030777012 scopus 로고    scopus 로고
    • The capsaicin receptor: A heat-activated ion channel in the pain pathway
    • Caterina, M.J.; Schumacher, M.A.; Tominaga, M.; Rosen T.A.; Levine, J.D.; Julius, D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature, 1997, 389(6653), 816-824.
    • (1997) Nature , vol.389 , Issue.6653 , pp. 816-824
    • Caterina, M.J.1    Schumacher, M.A.2    Tominaga, M.3    Rosen, T.A.4    Levine, J.D.5    Julius, D.6
  • 2
    • 0347504835 scopus 로고    scopus 로고
    • TRP channels as cellular sensors
    • Clapham, D.E. TRP channels as cellular sensors. Nature, 2003, 426(6966), 517-524.
    • (2003) Nature , vol.426 , Issue.6966 , pp. 517-524
    • Clapham, D.E.1
  • 3
    • 0036080482 scopus 로고    scopus 로고
    • TRP channel proteins and signal transduction
    • Minke, B.; Cook, B. TRP channel proteins and signal transduction. Physiol. Rev., 2002, 82(2), 429-472.
    • (2002) Physiol. Rev , vol.82 , Issue.2 , pp. 429-472
    • Minke, B.1    Cook, B.2
  • 4
    • 0035855860 scopus 로고    scopus 로고
    • Molecular mechanisms of nociception
    • Julius, D.; Basbaum, A.I. Molecular mechanisms of nociception. Nature, 2001, 413(6852), 203-210.
    • (2001) Nature , vol.413 , Issue.6852 , pp. 203-210
    • Julius, D.1    Basbaum, A.I.2
  • 5
    • 47749116508 scopus 로고    scopus 로고
    • TRPV1: A Target for Next Generation Analgesics
    • Premkumar, L.S.; Sikand, P. TRPV1: A Target for Next Generation Analgesics. Curr. Neuropharmacol, 2008, 6(2), 151-163.
    • (2008) Curr. Neuropharmacol , vol.6 , Issue.2 , pp. 151-163
    • Premkumar, L.S.1    Sikand, P.2
  • 6
    • 0035810934 scopus 로고    scopus 로고
    • Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia
    • Tominaga, M.; Wada, M.; Masu, M. Potentiation of capsaicin receptor activity by metabotropic ATP receptors as a possible mechanism for ATP-evoked pain and hyperalgesia. Proc. Natl. Acad. Sci. USA, 2001, 98(12), 6951-6956.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.12 , pp. 6951-6956
    • Tominaga, M.1    Wada, M.2    Masu, M.3
  • 7
    • 0036310523 scopus 로고    scopus 로고
    • Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1
    • Sugiura, T.; Tominaga, M.; Katsuya, H.; Mizumura, K. Bradykinin lowers the threshold temperature for heat activation of vanilloid receptor 1. J. Neurophysiol, 2002, 88(1), 544-548.
    • (2002) J. Neurophysiol , vol.88 , Issue.1 , pp. 544-548
    • Sugiura, T.1    Tominaga, M.2    Katsuya, H.3    Mizumura, K.4
  • 8
    • 0034926291 scopus 로고    scopus 로고
    • The vanilloid receptor: A molecular gate-way to the pain pathway
    • Caterina, M.J.; Julius, D. The vanilloid receptor: a molecular gate-way to the pain pathway. Annu. Rev. Neurosci., 2001, 24, 487-517.
    • (2001) Annu. Rev. Neurosci , vol.24 , pp. 487-517
    • Caterina, M.J.1    Julius, D.2
  • 9
    • 4644324408 scopus 로고    scopus 로고
    • Thermosensation and pain
    • Tominaga, M.; Caterina, M.J. Thermosensation and pain. J. Neurobiol., 2004, 61(1), 3-12.
    • (2004) J. Neurobiol , vol.61 , Issue.1 , pp. 3-12
    • Tominaga, M.1    Caterina, M.J.2
  • 10
    • 34249717691 scopus 로고    scopus 로고
    • Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse
    • Sikand, P.; Premkumar, L.S. Potentiation of glutamatergic synaptic transmission by protein kinase C-mediated sensitization of TRPV1 at the first sensory synapse. J. Physiol., 2007, 581(Pt 2), 631-647.
    • (2007) J. Physiol , vol.581 , Issue.Pt 2 , pp. 631-647
    • Sikand, P.1    Premkumar, L.S.2
  • 11
    • 27544451604 scopus 로고    scopus 로고
    • Heteromeri- zation andcolocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia
    • Rutter, A.R.; Ma, Q.P.; Leveridge, M.; Bonnert, T.P. Heteromeri- zation andcolocalization of TrpV1 and TrpV2 in mammalian cell lines and rat dorsal root ganglia. Neuroreport, 2005, 16(16), 1735-1739.
    • (2005) Neuroreport , vol.16 , Issue.16 , pp. 1735-1739
    • Rutter, A.R.1    Ma, Q.P.2    Leveridge, M.3    Bonnert, T.P.4
  • 13
    • 24144490391 scopus 로고    scopus 로고
    • Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex
    • Liapi, A.; Wood, J.N. Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. Eur. J. Neurosci., 2005, 22(4), 825-834.
    • (2005) Eur. J. Neurosci , vol.22 , Issue.4 , pp. 825-834
    • Liapi, A.1    Wood, J.N.2
  • 14
    • 0023898089 scopus 로고
    • Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides
    • Holzer, P. Local effector functions of capsaicin-sensitive sensory nerve endings: involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides. Neuroscience, 1988, 24(3), 739-768.
    • (1988) Neuroscience , vol.24 , Issue.3 , pp. 739-768
    • Holzer, P.1
  • 15
    • 22144434056 scopus 로고    scopus 로고
    • Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: Differences between the disc afferents and the cutaneous affer-ents
    • Aoki, Y.; Ohtori, S.; Takahashi, K.; Ino, H.; Douya, H.; Ozawa, T.; Saito, T.; Moriya, H. Expression and co-expression of VR1, CGRP, and IB4-binding glycoprotein in dorsal root ganglion neurons in rats: differences between the disc afferents and the cutaneous affer-ents. Spine, 2005, 30(13), 1496-1500.
    • (2005) Spine , vol.30 , Issue.13 , pp. 1496-1500
    • Aoki, Y.1    Ohtori, S.2    Takahashi, K.3    Ino, H.4    Douya, H.5    Ozawa, T.6    Saito, T.7    Moriya, H.8
  • 16
    • 12444274856 scopus 로고    scopus 로고
    • Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat
    • Kobayashi, K.; Fukuoka, T.; Yamanaka, H.; Dai, Y.; Obata, K.; Tokunaga, A.; Noguchi, K. Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat. J. Comp. Neurol, 2005, 481(4), 377-390.
    • (2005) J. Comp. Neurol , vol.481 , Issue.4 , pp. 377-390
    • Kobayashi, K.1    Fukuoka, T.2    Yamanaka, H.3    Dai, Y.4    Obata, K.5    Tokunaga, A.6    Noguchi, K.7
  • 19
    • 0037083311 scopus 로고    scopus 로고
    • Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord
    • Nakatsuka, T.; Furue, H.; Yoshimura, M.; Gu, J.G. Activation of central terminal vanilloid receptor-1 receptors and alpha beta-methylene-ATP-sensitive P2X receptors reveals a converged synaptic activity onto the deep dorsal horn neurons of the spinal cord. J. Neurosci., 2002, 22(4), 1228-1237.
    • (2002) J. Neurosci , vol.22 , Issue.4 , pp. 1228-1237
    • Nakatsuka, T.1    Furue, H.2    Yoshimura, M.3    Gu, J.G.4
  • 20
    • 0038187752 scopus 로고    scopus 로고
    • Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: Glutamate release by capsaicin and menthol
    • Baccei, M.L.; Bardoni, R.; Fitzgerald, M. Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: glutamate release by capsaicin and menthol. J. Physiol, 2003, 549(Pt 1), 231-242.
    • (2003) J. Physiol , vol.549 , Issue.Pt 1 , pp. 231-242
    • Baccei, M.L.1    Bardoni, R.2    Fitzgerald, M.3
  • 21
    • 30544438062 scopus 로고    scopus 로고
    • Downregulation of transient receptor potential melastatin 8 by protein kinase C-mediated dephosphorylation
    • Premkumar, L.S.; Raisinghani, M.; Pingle, S.C.; Long, C; Pimen-tel, F. Downregulation of transient receptor potential melastatin 8 by protein kinase C-mediated dephosphorylation. J. Neurosci., 2005, 25(49), 11322-11329.
    • (2005) J. Neurosci , vol.25 , Issue.49 , pp. 11322-11329
    • Premkumar, L.S.1    Raisinghani, M.2    Pingle, S.C.3    Long, C.4    Pimen-Tel, F.5
  • 22
    • 70349272715 scopus 로고    scopus 로고
    • Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia
    • Jeffry, J.A.; Yu, S.Q.; Sikand, P.; Parihar, A.; Evans, M.S.; Premkumar, L.S. Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia. PLoS One, 2009, 4(9), e7021.
    • (2009) PLoS One , vol.4 , Issue.9
    • Jeffry, J.A.1    Yu, S.Q.2    Sikand, P.3    Parihar, A.4    Evans, M.S.5    Premkumar, L.S.6
  • 23
    • 0037107184 scopus 로고    scopus 로고
    • Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius
    • Doyle, M.W.; Bailey, T.W.; Jin, Y.H.; Andresen, M.C. Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus solitarius. J. Neurosci., 2002, 22(18), 8222-8229.
    • (2002) J. Neurosci , vol.22 , Issue.18 , pp. 8222-8229
    • Doyle, M.W.1    Bailey, T.W.2    Jin, Y.H.3    Andresen, M.C.4
  • 24
    • 0036713282 scopus 로고    scopus 로고
    • Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro
    • Marinelli, S.; Vaughan, C; Christie, M.J.; Connor, M. Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro. J. Physiol, 2002, 543(Pt 2), 531-540.
    • (2002) J. Physiol , vol.543 , Issue.Pt 2 , pp. 531-540
    • Marinelli, S.1    Vaughan, C.2    Christie, M.J.3    Connor, M.4
  • 25
    • 0037996964 scopus 로고    scopus 로고
    • Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors
    • Marinelli, S.; Di Marzo, V.; Berretta, N.; Matias, I.; Maccarrone, M.; Bernardi, G.; Mercuri, N.B. Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. J. Neurosci., 2003, 23(8), 3136-3144.
    • (2003) J. Neurosci , vol.23 , Issue.8 , pp. 3136-3144
    • Marinelli, S.1    Di Marzo, V.2    Berretta, N.3    Matias, I.4    Maccarrone, M.5    Bernardi, G.6    Mercuri, N.B.7
  • 28
    • 0034724402 scopus 로고    scopus 로고
    • Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like im-munoreactivity, in the central nervous system of the rat and human
    • Mezey, E.; Toth, Z.E.; Cortright, D.N.; Arzubi, M.K.; Krause, J.E.; Elde, R.; Guo, A.; Blumberg, P.M.; Szallasi, A. Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like im-munoreactivity, in the central nervous system of the rat and human. Proc. Natl. Acad. Sci. USA, 2000, 97(7), 3655-3660.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.7 , pp. 3655-3660
    • Mezey, E.1    Toth, Z.E.2    Cortright, D.N.3    Arzubi, M.K.4    Krause, J.E.5    Elde, R.6    Guo, A.7    Blumberg, P.M.8    Szallasi, A.9
  • 29
    • 39449102203 scopus 로고    scopus 로고
    • Peripheral TRPV1 receptors as targets for drug development: New molecules and mechanisms
    • Gunthorpe, M.J.; Szallasi, A. Peripheral TRPV1 receptors as targets for drug development: new molecules and mechanisms. Curr. Pharm. Des., 2008, 14(1), 32-41.
    • (2008) Curr. Pharm. Des , vol.14 , Issue.1 , pp. 32-41
    • Gunthorpe, M.J.1    Szallasi, A.2
  • 30
  • 31
  • 32
    • 0038050408 scopus 로고    scopus 로고
    • Va-nilloid receptor expression in the rat tongue and palate
    • Kido, M.A.; Muroya, H., Yamaza, T., Terada, Y.; Tanaka, T. Va-nilloid receptor expression in the rat tongue and palate. J. Dent. Res., 2003, 82(5), 393-397.
    • (2003) J. Dent. Res , vol.82 , Issue.5 , pp. 393-397
    • Kido, M.A.1    Muroya, H.2    Yamaza, T.3    Terada, Y.4    Tanaka, T.5
  • 33
    • 2542452122 scopus 로고    scopus 로고
    • TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells
    • Vriens, J.; Janssens, A.; Prenen, J.; Nilius, B.; Wondergem, R. TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells. Cell Calcium, 2004, 36(1), 19-28.
    • (2004) Cell Calcium , vol.36 , Issue.1 , pp. 19-28
    • Vriens, J.1    Janssens, A.2    Prenen, J.3    Nilius, B.4    Wondergem, R.5
  • 34
    • 0037216692 scopus 로고    scopus 로고
    • Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes
    • Southall, M.D.; Li, T.; Gharibova, L.S.; Pei, Y.; Nicol, G.D.; Travers, J.B. Activation of epidermal vanilloid receptor-1 induces release of proinflammatory mediators in human keratinocytes. J. Pharmacol. Exp. Ther., 2003, 304(1), 217-222.
    • (2003) J. Pharmacol. Exp. Ther , vol.304 , Issue.1 , pp. 217-222
    • Southall, M.D.1    Li, T.2    Gharibova, L.S.3    Pei, Y.4    Nicol, G.D.5    Travers, J.B.6
  • 35
    • 0038662789 scopus 로고    scopus 로고
    • Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: Evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD
    • Heiner, I.; Eisfeld, J.; Halaszovich, C.R.; Wehage, E.; Jungling, E.; Zitt, C.; Luckhoff, A. Expression profile of the transient receptor potential (TRP) family in neutrophil granulocytes: evidence for currents through long TRP channel 2 induced by ADP-ribose and NAD. Biochem. J., 2003, 371(Pt 3), 1045-1053.
    • (2003) Biochem. J , vol.371 , Issue.Pt 3 , pp. 1045-1053
    • Heiner, I.1    Eisfeld, J.2    Halaszovich, C.R.3    Wehage, E.4    Jungling, E.5    Zitt, C.6    Luckhoff, A.7
  • 36
    • 0141783754 scopus 로고    scopus 로고
    • Vanilloid receptor activation by 2- and 10-micrometer particles induces responses leading to apoptosis in human airway epithelial cells
    • Agopyan, N.; Bhatti, T.; Yu, S.; Simon, S.A. Vanilloid receptor activation by 2- and 10-micrometer particles induces responses leading to apoptosis in human airway epithelial cells. Toxicol. Appl. Pharmacol., 2003, 192(1), 21-35.
    • (2003) Toxicol. Appl. Pharmacol , vol.192 , Issue.1 , pp. 21-35
    • Agopyan, N.1    Bhatti, T.2    Yu, S.3    Simon, S.A.4
  • 37
    • 70349694395 scopus 로고    scopus 로고
    • Expression of transient receptor potential vanilloid (TRPV) families 1, 2, 3 and 4 in the mouse olfactory epithelium
    • Ahmed, M.K.; Takumida, M.; Ishibashi, T.; Hamamoto, T.; Hira-kawa, K. Expression of transient receptor potential vanilloid (TRPV) families 1, 2, 3 and 4 in the mouse olfactory epithelium. Rhinology, 2009, 47(3), 242-247.
    • (2009) Rhinology , vol.47 , Issue.3 , pp. 242-247
    • Ahmed, M.K.1    Takumida, M.2    Ishibashi, T.3    Hamamoto, T.4    Hira-Kawa, K.5
  • 38
    • 70349311268 scopus 로고    scopus 로고
    • Ontogenetic expression of the vanilloid receptors TRPV1 and TRPV2 in the rat retina
    • Leonelli, M.; Martins, D.O.; Kihara, A.H.; Britto, L.R. Ontogenetic expression of the vanilloid receptors TRPV1 and TRPV2 in the rat retina. Int. J. Dev. Neurosci., 2009, 27(7), 709-718.
    • (2009) Int. J. Dev. Neurosci , vol.27 , Issue.7 , pp. 709-718
    • Leonelli, M.1    Martins, D.O.2    Kihara, A.H.3    Britto, L.R.4
  • 39
    • 0031283176 scopus 로고    scopus 로고
    • Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons
    • Lopshire, J.C.; Nicol, G.D. Activation and recovery of the PGE2-mediated sensitization of the capsaicin response in rat sensory neurons. J. Neurophysiol., 1997, 78(6), 3154-3164.
    • (1997) J. Neurophysiol , vol.78 , Issue.6 , pp. 3154-3164
    • Lopshire, J.C.1    Nicol, G.D.2
  • 40
    • 0032529562 scopus 로고    scopus 로고
    • The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: Whole-cell and single-channel studies
    • Lopshire, J.C.; Nicol, G.D. The cAMP transduction cascade mediates the prostaglandin E2 enhancement of the capsaicin-elicited current in rat sensory neurons: whole-cell and single-channel studies. J. Neurosci., 1998, 18(16), 6081-6092.
    • (1998) J. Neurosci , vol.18 , Issue.16 , pp. 6081-6092
    • Lopshire, J.C.1    Nicol, G.D.2
  • 41
    • 0030446311 scopus 로고    scopus 로고
    • A novel heat-activated current in noci-ceptive neurons and its sensitization by bradykinin [see comments]
    • Cesare, P.; McNaughton, P. A novel heat-activated current in noci-ceptive neurons and its sensitization by bradykinin [see comments]. Proc. Natl. Acad. Sci. USA, 1996, 93(26), 15435-15439.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , Issue.26 , pp. 15435-15439
    • Cesare, P.1    McNaughton, P.2
  • 42
    • 0034700494 scopus 로고    scopus 로고
    • Induction of vanilloid receptor channel activity by protein kinase C
    • Premkumar, L.S.; Ahern, G.P. Induction of vanilloid receptor channel activity by protein kinase C. Nature, 2000, 408(6815), 985-990.
    • (2000) Nature , vol.408 , Issue.6815 , pp. 985-990
    • Premkumar, L.S.1    Ahern, G.P.2
  • 43
    • 0036758636 scopus 로고    scopus 로고
    • Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: Potential mechanism for thermal hyperalgesia
    • Hu, H.J.; Bhave, G.; Gereau, R.W. Prostaglandin and protein kinase A-dependent modulation of vanilloid receptor function by metabotropic glutamate receptor 5: potential mechanism for thermal hyperalgesia. J. Neurosci., 2002, 22(17), 7444-7452.
    • (2002) J. Neurosci , vol.22 , Issue.17 , pp. 7444-7452
    • Hu, H.J.1    Bhave, G.2    Gereau, R.W.3
  • 44
    • 7444235361 scopus 로고    scopus 로고
    • TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation
    • Sugiuar, T.; Bielefeldt, K.; Gebhart, G.F. TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation. J. Neurosci., 2004, 24(43), 9521-9530.
    • (2004) J. Neurosci , vol.24 , Issue.43 , pp. 9521-9530
    • Sugiuar, T.1    Bielefeldt, K.2    Gebhart, G.F.3
  • 45
    • 2342466078 scopus 로고    scopus 로고
    • Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons
    • Kim, B.M.; Lee, S.H.; Shim, W.S.; Oh, U. Histamine-induced Ca(2+) influx via the PLA(2)/lipoxygenase/TRPV1 pathway in rat sensory neurons. Neurosci. Lett., 2004, 361(1-3),159-162.
    • (2004) Neurosci. Lett , vol.361 , Issue.1-3 , pp. 159-162
    • Kim, B.M.1    Lee, S.H.2    Shim, W.S.3    Oh, U.4
  • 46
    • 0032588211 scopus 로고    scopus 로고
    • Role of [Ca2+]i in the ATP-induced heat sensitization process of rat nociceptive neurons
    • Kress, M.; Guenther, S. Role of [Ca2+]i in the ATP-induced heat sensitization process of rat nociceptive neurons. J. Neurophysiol., 1999, 81(6), 2612-2619.
    • (1999) J. Neurophysiol , vol.81 , Issue.6 , pp. 2612-2619
    • Kress, M.1    Guenther, S.2
  • 47
    • 0034668893 scopus 로고    scopus 로고
    • Intracellular ATP increases capsaicin-activated channel activity by interacting with nucleotide-binding domains
    • Kwak, J.; Wang, M.H.; Hwang, S.W.; Kim, T.Y.; Lee, S.Y.; Oh, U. Intracellular ATP increases capsaicin-activated channel activity by interacting with nucleotide-binding domains. J. Neurosci., 2000, 20(22), 8298-8304.
    • (2000) J. Neurosci , vol.20 , Issue.22 , pp. 8298-8304
    • Kwak, J.1    Wang, M.H.2    Hwang, S.W.3    Kim, T.Y.4    Lee, S.Y.5    Oh, U.6
  • 49
    • 2442468123 scopus 로고    scopus 로고
    • Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain
    • Dai, Y.; Moriyama, T.; Higashi, T.; Togashi, K.; Kobayashi, K.; Yamanaka, H.; Tominaga, M.; Noguchi, K. Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain. J. Neurosci., 2004, 24(18), 4293-4299.
    • (2004) J. Neurosci , vol.24 , Issue.18 , pp. 4293-4299
    • Dai, Y.1    Moriyama, T.2    Higashi, T.3    Togashi, K.4    Kobayashi, K.5    Yamanaka, H.6    Tominaga, M.7    Noguchi, K.8
  • 50
    • 37249088295 scopus 로고    scopus 로고
    • Activin acutely sensitizes dorsal root ganglion neurons and induces hyper-algesia via PKC-mediated potentiation of transient receptor potential vanilloid I
    • Zhu, W.; Xu, P.; Cuascut, F.X.; Hall, A.K.; Oxford, G.S. Activin acutely sensitizes dorsal root ganglion neurons and induces hyper-algesia via PKC-mediated potentiation of transient receptor potential vanilloid I. J. Neurosci., 2007, 27(50), 13770-13780.
    • (2007) J. Neurosci , vol.27 , Issue.50 , pp. 13770-13780
    • Zhu, W.1    Xu, P.2    Cuascut, F.X.3    Hall, A.K.4    Oxford, G.S.5
  • 51
    • 11444252856 scopus 로고    scopus 로고
    • Differential regulation of 3-beta-hydroxysteroid dehydrogenase and vanilloid receptor TRPV1 mRNA in sensory neurons by capsaicin and NGF
    • Donnerer, J., Liebmann, I.; Schicho, R. Differential regulation of 3-beta-hydroxysteroid dehydrogenase and vanilloid receptor TRPV1 mRNA in sensory neurons by capsaicin and NGF. Pharmacology, 2005, 73(2), 97-101.
    • (2005) Pharmacology , vol.73 , Issue.2 , pp. 97-101
    • Donnerer, J.1    Liebmann, I.2    Schicho, R.3
  • 52
    • 8144222402 scopus 로고    scopus 로고
    • NGF and GDNF differentially regulate TRPV1 expression that contributes to development of inflammatory thermal hyperalgesia
    • Amaya, F.; Shimosato, G.; Nagano, M.; Ueda, M.; Hashimoto, S.; Tanaka, Y.; Suzuki, H.; Tanaka, M. NGF and GDNF differentially regulate TRPV1 expression that contributes to development of inflammatory thermal hyperalgesia. Eur. J. Neurosci., 2004, 20(9), 2303-2310.
    • (2004) Eur. J. Neurosci , vol.20 , Issue.9 , pp. 2303-2310
    • Amaya, F.1    Shimosato, G.2    Nagano, M.3    Ueda, M.4    Hashimoto, S.5    Tanaka, Y.6    Suzuki, H.7    Tanaka, M.8
  • 53
    • 33750524257 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane
    • Stein, A.T.; Ufret-Vincenty, C.A.; Hua, L.; Santana, L.F.; Gordon, S.E. Phosphoinositide 3-kinase binds to TRPV1 and mediates NGF-stimulated TRPV1 trafficking to the plasma membrane. J. Gen. Physiol., 2006, 128(5), 509-522.
    • (2006) J. Gen. Physiol , vol.128 , Issue.5 , pp. 509-522
    • Stein, A.T.1    Ufret-Vincenty, C.A.2    Hua, L.3    Santana, L.F.4    Gordon, S.E.5
  • 55
    • 0344011522 scopus 로고    scopus 로고
    • Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons
    • Sathianathan, V.; Avelino, A.; Charrua, A.; Santha, P.; Matesz, K.; Cruz, F.; Nagy, I. Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons. Eur. J. Neurosci., 2003, 18(9), 2477-2486.
    • (2003) Eur. J. Neurosci , vol.18 , Issue.9 , pp. 2477-2486
    • Sathianathan, V.1    Avelino, A.2    Charrua, A.3    Santha, P.4    Matesz, K.5    Cruz, F.6    Nagy, I.7
  • 59
    • 0042734414 scopus 로고    scopus 로고
    • Activation of TRPV1 by the satiety factor oleoyletha-nolamide
    • Ahern, G.P. Activation of TRPV1 by the satiety factor oleoyletha-nolamide. J. Biol. Chem., 2003, 278(33), 30429-30434.
    • (2003) J. Biol. Chem , vol.278 , Issue.33 , pp. 30429-30434
    • Ahern, G.P.1
  • 61
    • 0025110892 scopus 로고
    • Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes
    • Szallasi, A.; Blumberg, P.M. Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, by dorsal root ganglion membranes. Brain Res., 1990, 524(1), 106-111.
    • (1990) Brain Res , vol.524 , Issue.1 , pp. 106-111
    • Szallasi, A.1    Blumberg, P.M.2
  • 62
    • 0025250172 scopus 로고
    • Effect of resiniferatoxin pretreatment on the inflammatory response to phorbol-12-myristate-13-acetate in mouse strains with different susceptibilities to phorbol ester tumor promotion
    • Szallasi, A.; Blumberg, P.M. Effect of resiniferatoxin pretreatment on the inflammatory response to phorbol-12-myristate-13-acetate in mouse strains with different susceptibilities to phorbol ester tumor promotion. Carcinogenesis, 1990, 11(4), 583-587.
    • (1990) Carcinogenesis , vol.11 , Issue.4 , pp. 583-587
    • Szallasi, A.1    Blumberg, P.M.2
  • 63
    • 17144418518 scopus 로고    scopus 로고
    • Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1)
    • McNamara, F.N.; Randall, A.; Gunthorpe, M.J. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br. J. Pharmacol., 2005, 144(6), 781-790.
    • (2005) Br. J. Pharmacol , vol.144 , Issue.6 , pp. 781-790
    • McNamara, F.N.1    Randall, A.2    Gunthorpe, M.J.3
  • 64
    • 25644433563 scopus 로고    scopus 로고
    • Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism
    • Xu, H.; Blair, N.T.; Clapham, D.E. Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism. J. Neurosci., 2005, 25(39), 8924-8937.
    • (2005) J. Neurosci , vol.25 , Issue.39 , pp. 8924-8937
    • Xu, H.1    Blair, N.T.2    Clapham, D.E.3
  • 66
    • 33646845297 scopus 로고    scopus 로고
    • Polyamines are potent ligands for the capsaicin receptor TRPV1
    • Ahern, G.P.; Wang, X.; Miyares, R.L. Polyamines are potent ligands for the capsaicin receptor TRPV1. J. Biol. Chem., 2006, 281(13), 8991-8995.
    • (2006) J. Biol. Chem , vol.281 , Issue.13 , pp. 8991-8995
    • Ahern, G.P.1    Wang, X.2    Miyares, R.L.3
  • 67
    • 34547109138 scopus 로고    scopus 로고
    • TRPV1 as a key determinant in ciguatera and neurotoxic shellfish poisoning
    • Cuypers, E.; Yanagihara, A.; Rainier, J.D.; Tytgat, J. TRPV1 as a key determinant in ciguatera and neurotoxic shellfish poisoning. Biochem. Biophys. Res. Commun., 2007, 361(1), 214-217.
    • (2007) Biochem. Biophys. Res. Commun , vol.361 , Issue.1 , pp. 214-217
    • Cuypers, E.1    Yanagihara, A.2    Rainier, J.D.3    Tytgat, J.4
  • 69
    • 0035927651 scopus 로고    scopus 로고
    • Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
    • Chuang, H.H.; Prescott, E.D.; Kong, H.; Shields, S.; Jordt, S.E.; Basbaum, A.I.; Chao, M.V.; Julius, D. Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature, 2001, 411(6840), 957-962.
    • (2001) Nature , vol.411 , Issue.6840 , pp. 957-962
    • Chuang, H.H.1    Prescott, E.D.2    Kong, H.3    Shields, S.4    Jordt, S.E.5    Basbaum, A.I.6    Chao, M.V.7    Julius, D.8
  • 70
    • 0030340740 scopus 로고    scopus 로고
    • Specific binding of [3H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypothalamus, reticular formation and ventral thalamus membrane preparations
    • Acs, G.; Palkovits, M.; Blumberg, P.M. Specific binding of [3H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypothalamus, reticular formation and ventral thalamus membrane preparations. Life Sci., 1996, 59(22), 1899-1908.
    • (1996) Life Sci , vol.59 , Issue.22 , pp. 1899-1908
    • Acs, G.1    Palkovits, M.2    Blumberg, P.M.3
  • 71
    • 0037113918 scopus 로고    scopus 로고
    • Agonist recognition sites in the cytosolic tails of vanilloid receptor 1
    • Jung, J.; Lee, S.Y.; Hwang, S.W.; Cho, H.; Shin, J.; Kang, Y.S.; Kim, S.; Oh, U. Agonist recognition sites in the cytosolic tails of vanilloid receptor 1. J. Biol. Chem., 2002, 277(46), 44448-44454.
    • (2002) J. Biol. Chem , vol.277 , Issue.46 , pp. 44448-44454
    • Jung, J.1    Lee, S.Y.2    Hwang, S.W.3    Cho, H.4    Shin, J.5    Kang, Y.S.6    Kim, S.7    Oh, U.8
  • 72
    • 1542267774 scopus 로고    scopus 로고
    • Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain
    • Chou, M.Z.; Mtui, T.; Gao, Y.D.; Kohler, M.; Middleton, R.E. Resiniferatoxin binds to the capsaicin receptor (TRPV1) near the extracellular side of the S4 transmembrane domain. Biochemistry, 2004, 43(9), 2501-2511.
    • (2004) Biochemistry , vol.43 , Issue.9 , pp. 2501-2511
    • Chou, M.Z.1    Mtui, T.2    Gao, Y.D.3    Kohler, M.4    Middleton, R.E.5
  • 74
    • 25844477092 scopus 로고    scopus 로고
    • Activation of transient receptor potential vanilloid 1 (TRPV1) by resiniferatoxin
    • Raisinghani, M.; Pabbidi, R.M.; Premkumar, L.S. Activation of transient receptor potential vanilloid 1 (TRPV1) by resiniferatoxin. J. Physiol., 2005, 567(Pt 3), 771-786.
    • (2005) J. Physiol , vol.567 , Issue.Pt 3 , pp. 771-786
    • Raisinghani, M.1    Pabbidi, R.M.2    Premkumar, L.S.3
  • 76
    • 0030925247 scopus 로고    scopus 로고
    • Pharmacological characterization of the vanilloid receptor in the rat dorsal spinal cord
    • Wardle, K.A.; Ranson, J.; Sanger, G. J. Pharmacological characterization of the vanilloid receptor in the rat dorsal spinal cord. Br. J. Pharmacol., 1997, 121(5), 1012-1016.
    • (1997) Br. J. Pharmacol , vol.121 , Issue.5 , pp. 1012-1016
    • Wardle, K.A.1    Ranson, J.2    Sanger, G.J.3
  • 77
    • 0026338461 scopus 로고
    • Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro
    • Urban, L.; Dray, A. Capsazepine, a novel capsaicin antagonist, selectively antagonises the effects of capsaicin in the mouse spinal cord in vitro. Neurosci. Lett., 1991, 134(1), 9-11.
    • (1991) Neurosci. Lett , vol.134 , Issue.1 , pp. 9-11
    • Urban, L.1    Dray, A.2
  • 78
    • 0038467306 scopus 로고    scopus 로고
    • N-(4-tertiarybutylphenyl)-4-(3- chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharma- cokinetic properties
    • Valenzano, K.J.; Grant, E.R.; Wu, G.; Hachicha, M.; Schmid, L.; Tafesse, L.; Sun, Q.; Rotshteyn, Y.; Francis, J.; Limberis, J.; Malik, S.; Whittemore, E.R.; Hodges, D. N-(4-tertiarybutylphenyl)-4-(3- chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharma- cokinetic properties. J. Pharmacol. Exp. Ther., 2003, 306(1), 377-386.
    • (2003) J. Pharmacol. Exp. Ther , Issue.1 , pp. 377-386
    • Valenzano, K.J.1    Grant, E.R.2    Wu, G.3    Hachicha, M.4    Schmid, L.5    Tafesse, L.6    Sun, Q.7    Rotshteyn, Y.8    Francis, J.9    Limberis, J.10    Malik, S.11    Whittemore, E.R.12    Hodges, D.13
  • 79
    • 0030742250 scopus 로고    scopus 로고
    • Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture
    • Docherty, R.J.; Yeats, J.C.; Piper, A.S. Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture. Br. J. Pharmacol., 1997, 121(7), 1461-1467.
    • (1997) Br. J. Pharmacol , vol.121 , Issue.7 , pp. 1461-1467
    • Docherty, R.J.1    Yeats, J.C.2    Piper, A.S.3
  • 80
    • 0030792361 scopus 로고    scopus 로고
    • Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia
    • Liu, L.; Simon, S.A. Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia. Neurosci. Lett., 1997, 228(1), 29-32.
    • (1997) Neurosci. Lett , vol.228 , Issue.1 , pp. 29-32
    • Liu, L.1    Simon, S.A.2
  • 81
    • 0035173995 scopus 로고    scopus 로고
    • Iodoresiniferatoxin, a new potent vanilloid receptor antagonist
    • Wahl, P.; Foged, C.; Tullin, S.; Thomsen, C. Iodoresiniferatoxin, a new potent vanilloid receptor antagonist. Mol. Pharmacol., 2001, 59(1), 9-15.
    • (2001) Mol. Pharmacol , vol.59 , Issue.1 , pp. 9-15
    • Wahl, P.1    Foged, C.2    Tullin, S.3    Thomsen, C.4
  • 84
    • 33746836557 scopus 로고    scopus 로고
    • TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation
    • Lappin, S.C.; Randall, A.D.; Gunthorpe, M.J.; Morisset, V. TRPV1 antagonist, SB-366791, inhibits glutamatergic synaptic transmission in rat spinal dorsal horn following peripheral inflammation. Eur. J. Pharmacol, 2006, 540(1-3), 73-81.
    • (2006) Eur. J. Pharmacol , vol.540 , Issue.1-3 , pp. 73-81
    • Lappin, S.C.1    Randall, A.D.2    Gunthorpe, M.J.3    Morisset, V.4
  • 85
    • 0038128285 scopus 로고    scopus 로고
    • N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II in vivo characterization in rat models of inflammatory and neuropathic pain
    • Pomonis, J.D.; Harrison, J.E.; Mark, L.; Bristol, D.R.; Valenzano, K.J.; Walker, K. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II in vivo characterization in rat models of inflammatory and neuropathic pain. J. Pharmacol. Exp. Ther., 2003, 306(1), 387-393.
    • (2003) J. Pharmacol. Exp. Ther , vol.306 , Issue.1 , pp. 387-393
    • Pomonis, J.D.1    Harrison, J.E.2    Mark, L.3    Bristol, D.R.4    Valenzano, K.J.5    Walker, K.6
  • 88
    • 75349108628 scopus 로고    scopus 로고
    • Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia
    • Garami, A.; Shimansky, Y.P.; Pakai, E.; Oliveira, D.L.; Gavva, N.R.; Romanovsky, A.A. Contributions of different modes of TRPV1 activation to TRPV1 antagonist-induced hyperthermia. J. Neurosci., 2010, 30(4), 1435-1440.
    • (2010) J. Neurosci , vol.30 , Issue.4 , pp. 1435-1440
    • Garami, A.1    Shimansky, Y.P.2    Pakai, E.3    Oliveira, D.L.4    Gavva, N.R.5    Romanovsky, A.A.6
  • 90
    • 34248138496 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
    • Szallasi, A.; Cortright, D.N.; Blum, C.A.; Eid, S.R. The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat. Rev. Drug Discov., 2007, 6(5), 357-372.
    • (2007) Nat. Rev. Drug Discov , vol.6 , Issue.5 , pp. 357-372
    • Szallasi, A.1    Cortright, D.N.2    Blum, C.A.3    Eid, S.R.4
  • 93
    • 0019497081 scopus 로고
    • A re-evaluation of the neurochemical and antinociceptive effects of intrathecal capsaicin in the rat
    • Nagy, J.I.; Emson, P.C.; Iversen, L.L. A re-evaluation of the neurochemical and antinociceptive effects of intrathecal capsaicin in the rat. Brain Res., 1981, 211(2), 497-502.
    • (1981) Brain Res , vol.211 , Issue.2 , pp. 497-502
    • Nagy, J.I.1    Emson, P.C.2    Iversen, L.L.3
  • 94
    • 0018601372 scopus 로고
    • Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia
    • Yaksh, T.L.; Farb, D.H.; Leeman, S.E.; Jessell, T.M. Intrathecal capsaicin depletes substance P in the rat spinal cord and produces prolonged thermal analgesia. Science, 1979, 206(4417), 481-483.
    • (1979) Science , vol.206 , Issue.4417 , pp. 481-483
    • Yaksh, T.L.1    Farb, D.H.2    Leeman, S.E.3    Jessell, T.M.4
  • 95
    • 0021708519 scopus 로고
    • Neurophysiological effects of capsaicin
    • Russell, L.C.; Burchiel, K.J. Neurophysiological effects of capsaicin. Brain Res., 1984, 320(2-3), 165-176.
    • (1984) Brain Res , vol.320 , Issue.2-3 , pp. 165-176
    • Russell, L.C.1    Burchiel, K.J.2
  • 96
    • 33847792875 scopus 로고    scopus 로고
    • The TRPV1 receptor and nociception
    • Immke, D.C.; Gavva, N.R. The TRPV1 receptor and nociception. Semin. Cell. Dev. Biol, 2006, 17(5), 582-591.
    • (2006) Semin. Cell. Dev. Biol , vol.17 , Issue.5 , pp. 582-591
    • Immke, D.C.1    Gavva, N.R.2
  • 98
    • 40849124247 scopus 로고    scopus 로고
    • Direct role of streptozotocin in inducing thermal hyperalgesia by enhanced expression of transient receptor potential vanilloid 1 in sensory neurons
    • Pabbidi, R.M.; Cao, D.S.; Parihar, A.; Pauza, M.E.; Premkumar, L.S. Direct role of streptozotocin in inducing thermal hyperalgesia by enhanced expression of transient receptor potential vanilloid 1 in sensory neurons. Mol Pharmacol, 2008, 73(3), 995-1004.
    • (2008) Mol Pharmacol , vol.73 , Issue.3 , pp. 995-1004
    • Pabbidi, R.M.1    Cao, D.S.2    Parihar, A.3    Pauza, M.E.4    Premkumar, L.S.5
  • 99
    • 0343216992 scopus 로고
    • Vapour Pressure of H2(18)O ice (I) (-17 degrees C to 0 degrees C) and H2(18)O water (0 degrees C to 16 degrees C)
    • Jancso, G.; Pupezin, J.; Van Hook, W.A. Vapour Pressure of H2(18)O ice (I) (-17 degrees C to 0 degrees C) and H2(18)O water (0 degrees C to 16 degrees C). Nature, 1970, 225(5234), 723.
    • (1970) Nature , vol.225 , Issue.5234 , pp. 723
    • Jancso, G.1    Pupezin, J.2    van Hook, W.A.3
  • 102
    • 13844294354 scopus 로고    scopus 로고
    • Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin
    • Apostolidis, A.; Brady, C.M.; Yiangou, Y.; Davis, J.; Fowler, C.J.; Anand, P. Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin. Urology, 2005, 65(2), 400-405
    • (2005) Urology , vol.65 , Issue.2 , pp. 400-405
    • Apostolidis, A.1    Brady, C.M.2    Yiangou, Y.3    Davis, J.4    Fowler, C.J.5    Anand, P.6
  • 103
    • 0036293929 scopus 로고    scopus 로고
    • Relief of post-herpetic neuralgia by surgical removal of painful skin
    • Petersen, K.L.; Rice, F.L.; Suess, F.; Berro, M.; Rowbotham, M.C. Relief of post-herpetic neuralgia by surgical removal of painful skin. Pain, 2002, 98(1-2), 119-126.
    • (2002) Pain , vol.98 , Issue.1-2 , pp. 119-126
    • Petersen, K.L.1    Rice, F.L.2    Suess, F.3    Berro, M.4    Rowbotham, M.C.5
  • 105
    • 4444318878 scopus 로고    scopus 로고
    • Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors
    • Akerman, S.; Kaube, H.; Goadsby, P.J. Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors. Br. J. Pharmacol., 2004, 142(8), 1354-1360.
    • (2004) Br. J. Pharmacol , vol.142 , Issue.8 , pp. 1354-1360
    • Akerman, S.1    Kaube, H.2    Goadsby, P.J.3
  • 107
    • 0033523442 scopus 로고    scopus 로고
    • Epidural res-iniferatoxin induced prolonged regional analgesia to pain
    • Szabo, T.; Olah, Z.; Iadarola, M.J.; Blumberg, P.M. Epidural res-iniferatoxin induced prolonged regional analgesia to pain. Brain Res., 1999, 840(1-2), 92-98.
    • (1999) Brain Res , vol.840 , Issue.1-2 , pp. 92-98
    • Szabo, T.1    Olah, Z.2    Iadarola, M.J.3    Blumberg, P.M.4
  • 109
  • 110
  • 111
    • 28444446988 scopus 로고    scopus 로고
    • Heat and mechanical hyperalgesia in mice model of cancer pain
    • Asai, H.; Ozaki, N.; Shinoda, M.; Nagamine, K.; Tohnai, I.; Ueda, M.; Sugiura, Y. Heat and mechanical hyperalgesia in mice model of cancer pain. Pain, 2005, 117(1-2), 19-29.
    • (2005) Pain , vol.117 , Issue.1-2 , pp. 19-29
    • Asai, H.1    Ozaki, N.2    Shinoda, M.3    Nagamine, K.4    Tohnai, I.5    Ueda, M.6    Sugiura, Y.7
  • 112
    • 47549101002 scopus 로고    scopus 로고
    • Involvement of TRPV1 in nociceptive behavior in a rat model of cancer pain
    • Shinoda, M.; Ogino, A.; Ozaki, N.; Urano, H.; Hironaka, K.; Yasui, M.; Sugiura, Y. Involvement of TRPV1 in nociceptive behavior in a rat model of cancer pain. J. Pain, 2008, 9(8), 687-699.
    • (2008) J. Pain , vol.9 , Issue.8 , pp. 687-699
    • Shinoda, M.1    Ogino, A.2    Ozaki, N.3    Urano, H.4    Hironaka, K.5    Yasui, M.6    Sugiura, Y.7
  • 113
    • 58449106224 scopus 로고    scopus 로고
    • SB366791, a TRPV1 antagonist, potentiates analgesic effects of systemic morphine in a murine model of bone cancer pain
    • Niiyama, Y.; Kawamata, T.; Yamamoto, J.; Furuse, S.; Namiki, A. SB366791, a TRPV1 antagonist, potentiates analgesic effects of systemic morphine in a murine model of bone cancer pain. Br. J. Anaesth., 2009, 102(2), 251-258.
    • (2009) Br. J. Anaesth , vol.102 , Issue.2 , pp. 251-258
    • Niiyama, Y.1    Kawamata, T.2    Yamamoto, J.3    Furuse, S.4    Namiki, A.5
  • 114
    • 58149483491 scopus 로고    scopus 로고
    • TRPV1 antagonists: The challenges for therapeutic targeting
    • Khairatkar-Joshi, N.; Szallasi, A. TRPV1 antagonists: the challenges for therapeutic targeting. Trends Mol. Med., 2009, 15(1), 14-22.
    • (2009) Trends Mol. Med , vol.15 , Issue.1 , pp. 14-22
    • Khairatkar-Joshi, N.1    Szallasi, A.2
  • 115
    • 34250755449 scopus 로고    scopus 로고
    • Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with os-teoarthritis and rheumatoid arthritis
    • Engler, A.; Aeschlimann, A.; Simmen, B.R.; Michel, B.A.; Gay, R.E.; Gay, S.; Sprott, H. Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with os-teoarthritis and rheumatoid arthritis. Biochem. Biophys. Res. Commun., 2007, 59(4), 884-888.
    • (2007) Biochem. Biophys. Res. Commun , vol.59 , Issue.4 , pp. 884-888
    • Engler, A.1    Aeschlimann, A.2    Simmen, B.R.3    Michel, B.A.4    Gay, R.E.5    Gay, S.6    Sprott, H.7
  • 116
    • 23944442240 scopus 로고    scopus 로고
    • Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of os-teoarthritis
    • Fernihough, J.; Gentry, C.; Bevan, S.; Winter, J. Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of os-teoarthritis. Neurosci. Lett., 2005, 388(2), 75-80.
    • (2005) Neurosci. Lett , vol.388 , Issue.2 , pp. 75-80
    • Fernihough, J.1    Gentry, C.2    Bevan, S.3    Winter, J.4
  • 117
    • 56349085899 scopus 로고    scopus 로고
    • Increased expression of CGRP in sensory afferents of arthritic mice--effect of genetic deletion of the vanilloid receptor TRPV1
    • Chen, Y.; Willcockson, H.H.; Valtschanoff, J.G. Increased expression of CGRP in sensory afferents of arthritic mice--effect of genetic deletion of the vanilloid receptor TRPV1. Neuropeptides, 2008, 42(5-6), 551-556.
    • (2008) Neuropeptides , vol.42 , Issue.5-6 , pp. 551-556
    • Chen, Y.1    Willcockson, H.H.2    Valtschanoff, J.G.3
  • 118
    • 59249097735 scopus 로고    scopus 로고
    • Vanilloid receptor TRPV1-mediated phosphorylation of ERK in murine adjuvant arthritis
    • Chen, Y.; Willcockson, H.H.; Valtschanoff, J.G. Vanilloid receptor TRPV1-mediated phosphorylation of ERK in murine adjuvant arthritis. Osteoarthritis Cartilage, 2009 (A), 17(2), 244-251.
    • (2009) Osteoarthritis Cartilage , vol.17 , Issue.2 , pp. 244-251
    • Chen, Y.1    Willcockson, H.H.2    Valtschanoff, J.G.3
  • 120
    • 71549147547 scopus 로고    scopus 로고
    • Influence of the vanilloid receptor TRPV1 on the activation of spinal cord glia in mouse models of pain
    • Chen, Y.; Willcockson, H.H.; Valtschanoff, J.G. Influence of the vanilloid receptor TRPV1 on the activation of spinal cord glia in mouse models of pain. Exp. Neurol., 2009 (B), 220(2), 383-390.
    • (2009) Exp. Neurol , vol.220 , Issue.2 , pp. 383-390
    • Chen, Y.1    Willcockson, H.H.2    Valtschanoff, J.G.3
  • 121
    • 27444431571 scopus 로고    scopus 로고
    • The effects of intraarticular resiniferatoxin in experimental knee-joint arthritis
    • Kissin, E.Y.; Freitas, C.F.; Kissin, I. The effects of intraarticular resiniferatoxin in experimental knee-joint arthritis. Anesth. Analg., 2005, 101(5), 1433-1439.
    • (2005) Anesth. Analg , vol.101 , Issue.5 , pp. 1433-1439
    • Kissin, E.Y.1    Freitas, C.F.2    Kissin, I.3
  • 122
    • 26844527321 scopus 로고    scopus 로고
    • Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation
    • Keeble, J.; Russell, F.; Curtis, B.; Starr, A.; Pinter, E.; Brain, S.D. Involvement of transient receptor potential vanilloid 1 in the vascular and hyperalgesic components of joint inflammation. Arthritis Rheum., 2005, 52(10), 3248-3256.
    • (2005) Arthritis Rheum , vol.52 , Issue.10 , pp. 3248-3256
    • Keeble, J.1    Russell, F.2    Curtis, B.3    Starr, A.4    Pinter, E.5    Brain, S.D.6
  • 123
    • 0034115822 scopus 로고    scopus 로고
    • Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis
    • Lorton, D.; Lubahn, C.; Engan, C.; Schaller, J.; Felten, D.L.; Bellinger, D.L. Local application of capsaicin into the draining lymph nodes attenuates expression of adjuvant-induced arthritis. Neuroimmunomodulation, 2000, 7(3), 115-125.
    • (2000) Neuroimmunomodulation , vol.7 , Issue.3 , pp. 115-125
    • Lorton, D.1    Lubahn, C.2    Engan, C.3    Schaller, J.4    Felten, D.L.5    Bellinger, D.L.6
  • 124
    • 23044496253 scopus 로고    scopus 로고
    • A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves patho-physiological pain associated with inflammation and tissue injury in rats
    • Honore, P.; Wismer, C.T.; Mikusa, J.; Zhu, C.Z.; Zhong, C.; Gau-vin, D.M.; Gomtsyan, A.; El Kouhen, R.; Lee, C.H.; Marsh, K.; Sullivan, J.P.; Faltynek, C.R.; Jarvis, M.F. A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves patho-physiological pain associated with inflammation and tissue injury in rats. J. Pharmacol. Exp. Ther., 2005, 314(1), 410-421.
    • (2005) J. Pharmacol. Exp. Ther , vol.314 , Issue.1 , pp. 410-421
    • Honore, P.1    Wismer, C.T.2    Mikusa, J.3    Zhu, C.Z.4    Zhong, C.5    Gau-Vin, D.M.6    Gomtsyan, A.7    El Kouhen, R.8    Lee, C.H.9    Marsh, K.10    Sullivan, J.P.11    Faltynek, C.R.12    Jarvis, M.F.13
  • 127
    • 27744478564 scopus 로고    scopus 로고
    • Immunohistochemical distribution of vanilloid receptor, calcitonin-gene related peptide and substance P in gastrointestinal mucosa of patients with different gastrointestinal disorders
    • Domotor, A.; Peidl, Z.; Vincze, A.; Hunyady, B.; Szolcsanyi, J.; Kereskay, L.; Szekeres, G.; Mozsik, G. Immunohistochemical distribution of vanilloid receptor, calcitonin-gene related peptide and substance P in gastrointestinal mucosa of patients with different gastrointestinal disorders. Inflammopharmacology, 2005, 13(1-3), 161-177.
    • (2005) Inflammopharmacology , vol.13 , Issue.1-3 , pp. 161-177
    • Domotor, A.1    Peidl, Z.2    Vincze, A.3    Hunyady, B.4    Szolcsanyi, J.5    Kereskay, L.6    Szekeres, G.7    Mozsik, G.8
  • 129
    • 69449089475 scopus 로고    scopus 로고
    • Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner
    • Amantini, C.; Ballarini, P.; Caprodossi, S.; Nabissi, M.; Morelli, M.B.; Lucciarini, R.; Cardarelli, M.A.; Mammana, G.; Santoni G. Triggering of transient receptor potential vanilloid type 1 (TRPV1) by capsaicin induces Fas/CD95-mediated apoptosis of urothelial cancer cells in an ATM-dependent manner. Carcinogenesis, 2009, 30(8), 1320-1329.
    • (2009) Carcinogenesis , vol.30 , Issue.8 , pp. 1320-1329
    • Amantini, C.1    Ballarini, P.2    Caprodossi, S.3    Nabissi, M.4    Morelli, M.B.5    Lucciarini, R.6    Cardarelli, M.A.7    Mammana, G.8    Santoni, G.9
  • 130
    • 24644523380 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid type 1 (TRPV1) expression changes from normal urothelium to transitional cell carcinoma in human bladder
    • Lazzeri, M.; Vannucchi, M.G.; Spinelli, M.; Bizzoco, E.; Beneforti, P.; Turini, D.; Faussone-Pellegrini, M.S. Transient receptor potential vanilloid type 1 (TRPV1) expression changes from normal urothelium to transitional cell carcinoma in human bladder. Eur. Urol., 2005, 48(4), 691-698.
    • (2005) Eur. Urol , vol.48 , Issue.4 , pp. 691-698
    • Lazzeri, M.1    Vannucchi, M.G.2    Spinelli, M.3    Bizzoco, E.4    Beneforti, P.5    Turini, D.6    Faussone-Pellegrini, M.S.7
  • 134
    • 59149085858 scopus 로고    scopus 로고
    • Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis
    • Bode, A.M.; Cho, Y.Y.; Zheng, D.; Zhu, F.; Ericson, M.E.; Ma, W.Y.; Yao, K.; Dong, Z. Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis. Cancer Res., 2009, 69(3), 905-913.
    • (2009) Cancer Res , vol.69 , Issue.3 , pp. 905-913
    • Bode, A.M.1    Cho, Y.Y.2    Zheng, D.3    Zhu, F.4    Ericson, M.E.5    Ma, W.Y.6    Yao, K.7    Dong, Z.8
  • 135
    • 68249104761 scopus 로고    scopus 로고
    • Vanilloid-mediated apoptosis in prostate cancer cells through a TRPV-1 dependent and a TRPV-1-independent mechanism
    • Ziglioli, F.; Frattini, A.; Maestroni, U.; Dinale, F.; Ciufifeda, M.; Cortellini, P. Vanilloid-mediated apoptosis in prostate cancer cells through a TRPV-1 dependent and a TRPV-1-independent mechanism. Acta. Biomed., 2009, 80(1), 13-20.
    • (2009) Acta. Biomed , vol.80 , Issue.1 , pp. 13-20
    • Ziglioli, F.1    Frattini, A.2    Maestroni, U.3    Dinale, F.4    Ciufifeda, M.5    Cortellini, P.6
  • 136
    • 67349202773 scopus 로고    scopus 로고
    • Molecular mechanisms of TRP regulation in tumor growth and metastasis
    • Gkika, D.; Prevarskaya, N. Molecular mechanisms of TRP regulation in tumor growth and metastasis. Biochim. Biophys. Acta., 2009, 1793(6), 953-958.
    • (2009) Biochim. Biophys. Acta , vol.1793 , Issue.6 , pp. 953-958
    • Gkika, D.1    Prevarskaya, N.2
  • 137
    • 3543040629 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats
    • Akiba, Y.; Kato, S.; Katsube, K.; Nakamura, M.; Takeuchi, K.; Ishii, H.; Hibi, T. Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats. Biochem. Biophys. Res. Commun., 2004, 321(1), 219-225.
    • (2004) Biochem. Biophys. Res. Commun , vol.321 , Issue.1 , pp. 219-225
    • Akiba, Y.1    Kato, S.2    Katsube, K.3    Nakamura, M.4    Takeuchi, K.5    Ishii, H.6    Hibi, T.7
  • 138
    • 33846194056 scopus 로고    scopus 로고
    • Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes
    • Gram, D.X.; Ahrén, B.; Nagy, I.; Olsen, U.B.; Brand, C.L.; Sundler, F.; Tabanera, R.; Svendsen, O.; Carr, R.D.; Santha, P.; Wierup, N.; Hansen, A.J. Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes. Eur. J. Neurosci., 2007, 25(1), 213-223.
    • (2007) Eur. J. Neurosci , vol.25 , Issue.1 , pp. 213-223
    • Gram, D.X.1    Ahrén, B.2    Nagy, I.3    Olsen, U.B.4    Brand, C.L.5    Sundler, F.6    Tabanera, R.7    Svendsen, O.8    Carr, R.D.9    Santha, P.10    Wierup, N.11    Hansen, A.J.12
  • 140
    • 0030590242 scopus 로고    scopus 로고
    • Involvement of capsaicin-sensitive nerves in the regulation of glucose tolerance in diabetic rats
    • Guillot, E.; Coste, A.; Angel, I. Involvement of capsaicin-sensitive nerves in the regulation of glucose tolerance in diabetic rats. Life Sci., 1996, 59(12), 969-977.
    • (1996) Life Sci , vol.59 , Issue.12 , pp. 969-977
    • Guillot, E.1    Coste, A.2    Angel, I.3
  • 141
    • 0031865365 scopus 로고    scopus 로고
    • Neonatal de-afferentation of capsaicin-sensitive sensory nerves increases in vivo insulin sensitivity in conscious adult rats
    • Koopmans, S.J.; Leighton, B.; DeFronzo, R.A. Neonatal de-afferentation of capsaicin-sensitive sensory nerves increases in vivo insulin sensitivity in conscious adult rats. Diabetologia, 1998, 41(7), 813-820.
    • (1998) Diabetologia , vol.41 , Issue.7 , pp. 813-820
    • Koopmans, S.J.1    Leighton, B.2    Defronzo, R.A.3
  • 142
    • 14044260472 scopus 로고    scopus 로고
    • Sensory nerve de-sensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV
    • Gram, D.X.; Hansen, A.J.; Deacon, C.F.; Brand, C.L.; Ribel, U.; Wilken, M.; Carr, R.D.; Svendsen, O.; Ahrén, B. Sensory nerve de-sensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV. Eur. J. Pharmacol., 2005, 509(2-3), 211-217.
    • (2005) Eur. J. Pharmacol , vol.509 , Issue.2-3 , pp. 211-217
    • Gram, D.X.1    Hansen, A.J.2    Deacon, C.F.3    Brand, C.L.4    Ribel, U.5    Wilken, M.6    Carr, R.D.7    Svendsen, O.8    Ahrén, B.9
  • 144
    • 0029331457 scopus 로고
    • Resistance to aging-associated obesity in capsaicin-desensitized rats one year after treatment
    • Melnyk, A.; Himms-Hagen, J. Resistance to aging-associated obesity in capsaicin-desensitized rats one year after treatment. Obes. Res., 1995, 3(4), 337-344.
    • (1995) Obes. Res , vol.3 , Issue.4 , pp. 337-344
    • Melnyk, A.1    Himms-Hagen, J.2
  • 145
    • 33947596710 scopus 로고    scopus 로고
    • Effects of capsaicin on induction of apoptosis and inhibition of adipogenesis in 3T3-L1 cells
    • Hsu C.L.; Yen, G.C. Effects of capsaicin on induction of apoptosis and inhibition of adipogenesis in 3T3-L1 cells. J. Agric. Food Chem., 2007, 55(5), 1730-1736.
    • (2007) J. Agric. Food Chem , vol.55 , Issue.5 , pp. 1730-1736
    • Hsu, C.L.1    Yen, G.C.2
  • 146
    • 45449110183 scopus 로고    scopus 로고
    • Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution
    • Leung, F.W. Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution. Life Sci., 2008, 83(1-2), 1-5.
    • (2008) Life Sci , vol.83 , Issue.1-2 , pp. 1-5
    • Leung, F.W.1
  • 147
    • 58149394253 scopus 로고    scopus 로고
    • Effects of novel capsinoid treatment on fatness and energy metabolism in humans: Possible phar-macogenetic implications
    • Snitker, S.; Fujishima, Y.; Shen, H.; Ott, S.; Pi-Sunyer, X.; Furu-hata, Y.; Sato, H.; Takahashi, M. Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible phar-macogenetic implications. Am. J. Clin. Nutr., 2009, 89(1), 45-50.
    • (2009) Am. J. Clin. Nutr , vol.89 , Issue.1 , pp. 45-50
    • Snitker, S.1    Fujishima, Y.2    Shen, H.3    Ott, S.4    Pi-Sunyer, X.5    Furu-Hata, Y.6    Sato, H.7    Takahashi, M.8
  • 148
    • 44749085444 scopus 로고    scopus 로고
    • TRPV1-null mice are protected from diet-induced obesity
    • Motter, A.L.; Ahern, G.P. TRPV1-null mice are protected from diet-induced obesity. FEBS Lett., 2008, 582(15), 2257-2262.
    • (2008) FEBS Lett , vol.582 , Issue.15 , pp. 2257-2262
    • Motter, A.L.1    Ahern, G.P.2
  • 149
    • 17844392649 scopus 로고    scopus 로고
    • Oleoylethanolamide excites vagal sensory neurons, induces visceral pain and reduced short-term food intake in mice via capsaicin receptor TRPV1
    • Wang, X.; Miyaress, R.L,; Ahern, G.P. Oleoylethanolamide excites vagal sensory neurons, induces visceral pain and reduced short-term food intake in mice via capsaicin receptor TRPV1. J. Physiol., 2005, 564(Pt 2), 541-547.
    • (2005) J. Physiol , vol.564 , Issue.Pt 2 , pp. 541-547
    • Wang, X.1    Miyaress, R.L.2    Ahern, G.P.3
  • 150
    • 0026527890 scopus 로고
    • Long-term decrease in body fat and in brown adipose tissue in capsaicin-desensitized rats
    • Cui, J.; Himms-Hagen, J. Long-term decrease in body fat and in brown adipose tissue in capsaicin-desensitized rats. Am. J. Physiol., 1992, 262(4 Pt 2), 568-573.
    • (1992) Am. J. Physiol , vol.262 , Issue.4 Pt 2 , pp. 568-573
    • Cui, J.1    Himms-Hagen, J.2
  • 152
    • 13544259733 scopus 로고    scopus 로고
    • Immunohistochemical localization of vanilloid receptor subtype 1 (TRPV1) in the guinea pig respiratory system
    • Watanabe, N.; Horie, S.; Michael, G.J.; Spina, D.; Page, C.P.; Priestley, J.V. Immunohistochemical localization of vanilloid receptor subtype 1 (TRPV1) in the guinea pig respiratory system. Pulm. Pharmacol. Ther., 2005, 18(3),187-197.
    • (2005) Pulm. Pharmacol. Ther , vol.18 , Issue.3 , pp. 187-197
    • Watanabe, N.1    Horie, S.2    Michael, G.J.3    Spina, D.4    Page, C.P.5    Priestley, J.V.6
  • 153
    • 33746471163 scopus 로고    scopus 로고
    • Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV) 1 and sensory neuropep-tides in the guinea-pig respiratory system
    • Watanabe, N.; Horie, S.; Michael, G.J.; Keir, D.; Spina, D.; Page, C.P.; Priestley, J.V. Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV) 1 and sensory neuropep-tides in the guinea-pig respiratory system. Neuroscience, 2006, 141(3), 1533-1543.
    • (2006) Neuroscience , vol.141 , Issue.3 , pp. 1533-1543
    • Watanabe, N.1    Horie, S.2    Michael, G.J.3    Keir, D.4    Spina, D.5    Page, C.P.6    Priestley, J.V.7
  • 154
    • 0036714577 scopus 로고    scopus 로고
    • Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig
    • Kollarik, M.; Undem, B.J. Mechanisms of acid-induced activation of airway afferent nerve fibres in guinea-pig. J. Physiol., 2002, 543(Pt 2), 591-600.
    • (2002) J. Physiol , vol.543 , Issue.Pt 2 , pp. 591-600
    • Kollarik, M.1    Undem, B.J.2
  • 155
    • 0035803998 scopus 로고    scopus 로고
    • Mechanisms of citric acid-induced bronchocon-striction
    • Ricciardolo, F.L. Mechanisms of citric acid-induced bronchocon-striction. Am. J. Med., 2001, 111 (Suppl 8A), 18S-24S.
    • (2001) Am. J. Med , vol.111 , Issue.SUPPL. 8A
    • Ricciardolo, F.L.1
  • 156
    • 34547421180 scopus 로고    scopus 로고
    • Role of TRPV receptors in respiratory diseases
    • Jia, Y.; Lee, L.Y. Role of TRPV receptors in respiratory diseases. Biochim. Biophys. Acta., 2007, 1772(8), 915-927.
    • (2007) Biochim. Biophys. Acta , vol.1772 , Issue.8 , pp. 915-927
    • Jia, Y.1    Lee, L.Y.2
  • 157
    • 33746584487 scopus 로고    scopus 로고
    • Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels
    • Groth, M.; Helbig, T., Grau, V., Kummer, W.; Haberberger, R.V. Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels. Respir. Res., 2006, 7(1), 96.
    • (2006) Respir. Res , vol.7 , Issue.1 , pp. 96
    • Groth, M.1    Helbig, T.2    Grau, V.3    Kummer, W.4    Haberberger, R.V.5
  • 158
    • 0034110869 scopus 로고    scopus 로고
    • Role of tachykinins in asthma
    • Joos, G.F.; Germonpre, P.R.; Pauwels, R.A. Role of tachykinins in asthma. Allergy, 2000, 55(4), 321-337.
    • (2000) Allergy , vol.55 , Issue.4 , pp. 321-337
    • Joos, G.F.1    Germonpre, P.R.2    Pauwels, R.A.3
  • 159
    • 0000040381 scopus 로고
    • Airway neuropeptides and asthma (Chapter 14)
    • in: M. Kaliner, P. Barnes, C. Persson (Eds.), Dekker, New York
    • Barnes, P.; Lundberg, J. Airway neuropeptides and asthma (Chapter 14), in: M. Kaliner, P. Barnes, C. Persson (Eds.), Asthma: Its Pathology and treatment, vol. 49, Dekker, New York, 1991.
    • (1991) Asthma: Its Pathology and Treatment , vol.49
    • Barnes, P.1    Lundberg, J.2
  • 160
    • 0020606221 scopus 로고
    • Substance P and cap-saicin-induced contraction of human bronchi
    • Lundberg, J.M.; Martling, C.R.; Saria, A. Substance P and cap-saicin-induced contraction of human bronchi. Acta Physiol. Scand, 1983, 119(1), 49-53.
    • (1983) Acta Physiol. Scand , vol.119 , Issue.1 , pp. 49-53
    • Lundberg, J.M.1    Martling, C.R.2    Saria, A.3
  • 162
    • 3142624679 scopus 로고    scopus 로고
    • Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough
    • Niimi, A.; Nguyen, L.T.; Usmani, O.; Mann B.; Chung, K.F. Reduced pH and chloride levels in exhaled breath condensate of patients with chronic cough. Thorax, 2004, 59(7), 608-612.
    • (2004) Thorax , vol.59 , Issue.7 , pp. 608-612
    • Niimi, A.1    Nguyen, L.T.2    Usmani, O.3    Mann, B.4    Chung, K.F.5
  • 163
    • 61649111137 scopus 로고    scopus 로고
    • TRPV1 receptors in sensitisation of cough and pain reflexes
    • Adcock, J.J. TRPV1 receptors in sensitisation of cough and pain reflexes. Pulm. Pharmacol. Ther., 2009, 22(2), 65-70.
    • (2009) Pulm. Pharmacol. Ther , vol.22 , Issue.2 , pp. 65-70
    • Adcock, J.J.1
  • 164
    • 11944267738 scopus 로고    scopus 로고
    • Exhaled breath condensate pH and exhaled nitric oxide in allergic asthma and in cystic fibrosis
    • Ojoo, C.; Mulrennan, S.A.; Kastelik, J.A.; Morice A.H.; Redington, A.E. Exhaled breath condensate pH and exhaled nitric oxide in allergic asthma and in cystic fibrosis. Thorax, 2005, 60(1), 22-26.
    • (2005) Thorax , vol.60 , Issue.1 , pp. 22-26
    • Ojoo, C.1    Mulrennan, S.A.2    Kastelik, J.A.3    Morice, A.H.4    Redington, A.E.5
  • 167
    • 0017388851 scopus 로고
    • Carbon dioxide flow and exercise hyperpnea: Cause and effect
    • Wasserman, K.; Whipp, B.J.; Casaburi, R.; Beaver, W.L. Carbon dioxide flow and exercise hyperpnea: Cause and effect. Am. Rev. Respir. Dis., 1977, 115(6 Pt 2), 225-237.
    • (1977) Am. Rev. Respir. Dis , vol.115 , Issue.6 Pt 2 , pp. 225-237
    • Wasserman, K.1    Whipp, B.J.2    Casaburi, R.3    Beaver, W.L.4
  • 168
    • 0023893399 scopus 로고
    • Effect of metabolic products of muscular contraction on discharge of group III and IV afferents
    • Rotto, D.M.; Kaufman, M.P. Effect of metabolic products of muscular contraction on discharge of group III and IV afferents. J. Appl. Physiol., 1988, 64(6), 2306-2313.
    • (1988) J. Appl. Physiol , vol.64 , Issue.6 , pp. 2306-2313
    • Rotto, D.M.1    Kaufman, M.P.2
  • 169
    • 33748464208 scopus 로고    scopus 로고
    • Thermal sensitivity of isolated vagal pulmonary sensory neurons: Role of transient receptor potential vanilloid receptors
    • Ni, D.; Gu, Q.; Hu, H.Z.; Gao, N.; Zhu, M.X.; Lee, L.Y. Thermal sensitivity of isolated vagal pulmonary sensory neurons: role of transient receptor potential vanilloid receptors. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2006, 291(3), R541-R550.
    • (2006) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.291 , Issue.3 , pp. 541-550
    • Ni, D.1    Gu, Q.2    Hu, H.Z.3    Gao, N.4    Zhu, M.X.5    Lee, L.Y.6
  • 171
    • 33644800014 scopus 로고    scopus 로고
    • Extending the understanding of sensory neuropeptides
    • De Swert, K.O.; Joos, G.F. Extending the understanding of sensory neuropeptides. Eur. J. Pharmacol., 2006, 533(1-3), 171-181.
    • (2006) Eur. J. Pharmacol , vol.533 , Issue.1-3 , pp. 171-181
    • de Swert, K.O.1    Joos, G.F.2
  • 172
    • 0036856216 scopus 로고    scopus 로고
    • Anandamide induces cough in conscious guinea-pigs through VR1 receptors
    • Jia, Y.; McLeod, R.L.; Wang, X.; Parra, L.E.; Egan R.W.; Hey, J.A. Anandamide induces cough in conscious guinea-pigs through VR1 receptors. Br. J. Pharmacol., 2002, 137(6), 831-836.
    • (2002) Br. J. Pharmacol , vol.137 , Issue.6 , pp. 831-836
    • Jia, Y.1    McLeod, R.L.2    Wang, X.3    Parra, L.E.4    Egan, R.W.5    Hey, J.A.6
  • 173
  • 174
    • 0028805448 scopus 로고
    • Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs
    • Lalloo, U.G.; Fox, A.J.; Belvisi, M.G.; Chung, K.F.; Barnes, P.J. Capsazepine inhibits cough induced by capsaicin and citric acid but not by hypertonic saline in guinea pigs. Appl. Physiol., 1995, 79(4), 1082-1087.
    • (1995) Appl. Physiol , vol.79 , Issue.4 , pp. 1082-1087
    • Lalloo, U.G.1    Fox, A.J.2    Belvisi, M.G.3    Chung, K.F.4    Barnes, P.J.5
  • 176
    • 35548999215 scopus 로고    scopus 로고
    • Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea-pigs
    • Bhattacharya, A.; Scott, B.P.; Nasser, N.; Ao, H.; Maher, M.P.; Dubin, A.E.; Swanson, D.M.; Shankley, N.P., Wickenden, A.D., Chaplan, S.R. Pharmacology and antitussive efficacy of 4-(3-trifluoromethyl-pyridin-2-yl)-piperazine-1-carboxylic acid (5-trifluoromethyl-pyridin-2-yl)-amide (JNJ17203212), a transient receptor potential vanilloid 1 antagonist in guinea-pigs. J. Pharmacol. Exp. Ther., 2007, 323(2), 665-674.
    • (2007) J. Pharmacol. Exp. Ther , vol.323 , Issue.2 , pp. 665-674
    • Bhattacharya, A.1    Scott, B.P.2    Nasser, N.3    Ao, H.4    Maher, M.P.5    Dubin, A.E.6    Swanson, D.M.7    Shankley, N.P.8    Wickenden, A.D.9    Chaplan, S.R.10
  • 177
    • 34248146986 scopus 로고    scopus 로고
    • TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitised guinea-pigs
    • McLeod, R.L.; Fernandez, X.; Correll, C.C.; Phelps, T.P.; Jia, Y.; Wang X.; Hey, J.A. TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitised guinea-pigs. Cough, 2006, 2(15), 10.
    • (2006) Cough , vol.2 , Issue.15 , pp. 10
    • McLeod, R.L.1    Fernandez, X.2    Correll, C.C.3    Phelps, T.P.4    Jia, Y.5    Wang, X.6    Hey, J.A.7
  • 178
    • 0023250638 scopus 로고
    • Capsaicin desensitization protects from antigen-induced bronchospasm in conscious guinea-pigs
    • Manzini, S.; Maggi, C.A.; Geppetti P.; Bacciarelli, C. Capsaicin desensitization protects from antigen-induced bronchospasm in conscious guinea-pigs. Eur. J. Pharmacol., 1987, 138(2), 307-308.
    • (1987) Eur. J. Pharmacol , vol.138 , Issue.2 , pp. 307-308
    • Manzini, S.1    Maggi, C.A.2    Geppetti, P.3    Bacciarelli, C.4
  • 180
    • 0031045816 scopus 로고    scopus 로고
    • Tachykinin-independent effects of capsaicin on smooth muscle in human isolated bronchi
    • Ellis, J.L.; Sham, J.S.; Undem, B.J. Tachykinin-independent effects of capsaicin on smooth muscle in human isolated bronchi. Am. J. Respir. Crit. Care. Med., 1997, 155(2), 751-755.
    • (1997) Am. J. Respir. Crit. Care. Med , vol.155 , Issue.2 , pp. 751-755
    • Ellis, J.L.1    Sham, J.S.2    Undem, B.J.3
  • 181
    • 0027231467 scopus 로고
    • Peptide-containing nerve fibers in human airways: Distribution and coexistence pattern
    • Lus, A.; Uddman, R.; Alm, P.; Basterra, J.; Sundler, F. Peptide-containing nerve fibers in human airways: distribution and coexistence pattern. Int. Arch. Allergy Immunol, 1993, 101(1), 52-60.
    • (1993) Int. Arch. Allergy Immunol , vol.101 , Issue.1 , pp. 52-60
    • Lus, A.1    Uddman, R.2    Alm, P.3    Basterra, J.4    Sundler, F.5
  • 182
    • 10644240946 scopus 로고    scopus 로고
    • Mucociliary dysfunction in COPD: Effect of current pharmacotherapeutic options
    • Rogers, D.F. Mucociliary dysfunction in COPD: effect of current pharmacotherapeutic options. Pulm. Pharmacol. Ther., 2005, 18(1), 1-8.
    • (2005) Pulm. Pharmacol. Ther , vol.18 , Issue.1 , pp. 1-8
    • Rogers, D.F.1
  • 183
    • 8444245629 scopus 로고    scopus 로고
    • Inflammatory cells as source of tachykinin-induced mucus secretion in chronic bronchitis
    • Springer, J.; Groneberg, D.A.; Pregla, R.; Fischer, A. Inflammatory cells as source of tachykinin-induced mucus secretion in chronic bronchitis. Regul. Pept, 2005, 124(1-3), 195-201.
    • (2005) Regul. Pept , vol.124 , Issue.1-3 , pp. 195-201
    • Springer, J.1    Groneberg, D.A.2    Pregla, R.3    Fischer, A.4
  • 184
    • 34247279786 scopus 로고    scopus 로고
    • Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging
    • Karmouty-Quintana, H.; Cannet, C; Sugar, R.; Fozard, J.R.; Page C.P.; Beckmann, N. Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging. Br. J. Pharmacol, 2007, 150(8), 1022-1030.
    • (2007) Br. J. Pharmacol , vol.150 , Issue.8 , pp. 1022-1030
    • Karmouty-Quintana, H.1    Cannet, C.2    Sugar, R.3    Fozard, J.R.4    Page, C.P.5    Beckmann, N.6
  • 185
    • 24944487186 scopus 로고    scopus 로고
    • Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells
    • Reilly, C.A.; Johansen, M.E.; Lanza, D.L.; Lee, J.; Lim J.O.; Yost, G.S. Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells. J. Biochem. Mol. Toxicol, 2005, 19(4), 266-275.
    • (2005) J. Biochem. Mol. Toxicol , vol.19 , Issue.4 , pp. 266-275
    • Reilly, C.A.1    Johansen, M.E.2    Lanza, D.L.3    Lee, J.4    Lim, J.O.5    Yost, G.S.6
  • 186
    • 34248578146 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells
    • Thomas, K.C.; Sabnis, A.S.; Johansen, M.E.; Lanza, D.L.; Moos, P.J.; Yost, S.; Reilly, C.A. Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. J. Pharmacol. Exp. Ther., 2007, 321(3), 830-838.
    • (2007) J. Pharmacol. Exp. Ther , vol.321 , Issue.3 , pp. 830-838
    • Thomas, K.C.1    Sabnis, A.S.2    Johansen, M.E.3    Lanza, D.L.4    Moos, P.J.5    Yost, S.6    Reilly, C.A.7
  • 188
    • 52949149710 scopus 로고    scopus 로고
    • Distinct chemical classes of medium-sized transient receptor potential channel vanilloid 1-immunoreactive dorsal root ganglion neurons innervate the adult mouse jejunum and colon
    • Tan, L.L.; Bornstein, J.C.; Anderson, C.R. Distinct chemical classes of medium-sized transient receptor potential channel vanilloid 1-immunoreactive dorsal root ganglion neurons innervate the adult mouse jejunum and colon. Neuroscience, 2008, 156(2), 334-343.
    • (2008) Neuroscience , vol.156 , Issue.2 , pp. 334-343
    • Tan, L.L.1    Bornstein, J.C.2    Anderson, C.R.3
  • 189
    • 68949131298 scopus 로고    scopus 로고
    • Neurochemical and morphological phenotypes of vagal afferent neurons innervating the adult mouse jejunum
    • Tan, L.L.; Bornstein, J.C.; Anderson, C.R. Neurochemical and morphological phenotypes of vagal afferent neurons innervating the adult mouse jejunum. Neurogastroenterol. Motil., 2009, 21(9), 994-1001.
    • (2009) Neurogastroenterol. Motil , vol.21 , Issue.9 , pp. 994-1001
    • Tan, L.L.1    Bornstein, J.C.2    Anderson, C.R.3
  • 190
    • 2442608827 scopus 로고    scopus 로고
    • Activation and sensitisation of the vanilloid receptor: Role in gastrointestinal inflammation and function
    • Geppetti, P.; Trevisani, M. Activation and sensitisation of the vanilloid receptor: role in gastrointestinal inflammation and function. Br. J. Pharmacol, 2004, 141(8), 1313-20.
    • (2004) Br. J. Pharmacol , vol.141 , Issue.8 , pp. 1313-1320
    • Geppetti, P.1    Trevisani, M.2
  • 191
    • 0042261608 scopus 로고    scopus 로고
    • Expression of vanilloid receptors in rat gastric epithelial cells: Role in cellular protection
    • Kato, S.; Aihara, E.; Nakamura, A.; Xin, H.; Matsui, H.; Kohama, K.; Takeuchi, K. Expression of vanilloid receptors in rat gastric epithelial cells: role in cellular protection. Biochem. Pharmacol, 2003, 66(6), 1115-1121.
    • (2003) Biochem. Pharmacol , vol.66 , Issue.6 , pp. 1115-1121
    • Kato, S.1    Aihara, E.2    Nakamura, A.3    Xin, H.4    Matsui, H.5    Kohama, K.6    Takeuchi, K.7
  • 192
    • 61649128432 scopus 로고    scopus 로고
    • Cough and gastroesophageal reflux: Insights from animal models
    • Kollarik, M.; Brozmanova, M. Cough and gastroesophageal reflux: insights from animal models. Pulm. Pharmacol. Ther., 2009, 22(2), 130-134.
    • (2009) Pulm. Pharmacol. Ther , vol.22 , Issue.2 , pp. 130-134
    • Kollarik, M.1    Brozmanova, M.2
  • 193
    • 70049102041 scopus 로고    scopus 로고
    • Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man
    • Kindt, S.; Vos, R.; Blondeau, K.; Tack, J. Influence of intra-oesophageal capsaicin instillation on heartburn induction and oesophageal sensitivity in man. Neurogastroenterol. Motil., 2009, 21(10), 1032-e82
    • (2009) Neurogastroenterol. Motil , vol.21 , Issue.10
    • Kindt, S.1    Vos, R.2    Blondeau, K.3    Tack, J.4
  • 195
    • 38649111659 scopus 로고    scopus 로고
    • Differential effects of ASIC3 and TRPV1 deletion on gastroesophageal sensation in mice
    • Bielefeldt, K.; Davis, B.M. Differential effects of ASIC3 and TRPV1 deletion on gastroesophageal sensation in mice. Am. J. Physiol. Gastrointest. Liver Physiol., 2008, 294(1), G130-138.
    • (2008) Am. J. Physiol. Gastrointest. Liver Physiol , vol.294 , Issue.1 , pp. 130-138
    • Bielefeldt, K.1    Davis, B.M.2
  • 197
    • 33744940067 scopus 로고    scopus 로고
    • Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum
    • Akiba, Y.; Ghayouri, S.; Takeuchi, T.; Mizumori, M.; Guth, P.H.; Engel, E.; Swenson, E.R.; Kaunitz, J.D. Carbonic anhydrases and mucosal vanilloid receptors help mediate the hyperemic response to luminal CO2 in rat duodenum. Gastroenterology, 2006, 131(1),
    • (2006) Gastroenterology , vol.131 , Issue.1
    • Akiba, Y.1    Ghayouri, S.2    Takeuchi, T.3    Mizumori, M.4    Guth, P.H.5    Engel, E.6    Swenson, E.R.7    Kaunitz, J.D.8
  • 198
    • 34447616977 scopus 로고    scopus 로고
    • Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score
    • Yilmaz, Z.; Renton, T.; Yiangou, Y.; Zakrzewska, J.; Chessell, I.P.; Bountra, C.; Anand, P. Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score. J. Clin. Neuro-sci., 2007, 14(9), 864-871.
    • (2007) J. Clin. Neuro-sci , vol.14 , Issue.9 , pp. 864-871
    • Yilmaz, Z.1    Renton, T.2    Yiangou, Y.3    Zakrzewska, J.4    Chessell, I.P.5    Bountra, C.6    Anand, P.7
  • 202
    • 11144255122 scopus 로고    scopus 로고
    • Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice
    • Kimball, E.S.; Wallace, N.H.; Schneider, C.R.; D'Andrea, M.R.; Hornby, P.J. Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice. Neurogastroenterol. Motil., 2004, 16(6), 811-818.
    • (2004) Neurogastroenterol. Motil , vol.16 , Issue.6 , pp. 811-818
    • Kimball, E.S.1    Wallace, N.H.2    Schneider, C.R.3    D'andrea, M.R.4    Hornby, P.J.5
  • 203
    • 32044436722 scopus 로고    scopus 로고
    • Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid induced colitis
    • Massa, F.; Sibaev, A.; Marsicano, G.; Blaudzun, H.; Storr, M.; Lutz, B. Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid induced colitis. J. Mol. Med., 2006, 84(2), 142-146.
    • (2006) J. Mol. Med , vol.84 , Issue.2 , pp. 142-146
    • Massa, F.1    Sibaev, A.2    Marsicano, G.3    Blaudzun, H.4    Storr, M.5    Lutz, B.6
  • 204
    • 11144319956 scopus 로고    scopus 로고
    • Vanilloid receptor TRPV1: Hot on the tongue and inflaming the colon
    • Holzer, P. Vanilloid receptor TRPV1: hot on the tongue and inflaming the colon. Neurogastroenterol. Motil., 2004, 16(6), 697-699.
    • (2004) Neurogastroenterol. Motil , vol.16 , Issue.6 , pp. 697-699
    • Holzer, P.1
  • 205
    • 0038070335 scopus 로고    scopus 로고
    • Chili pepper and rectal hyperalgesia in irritable bowel syndrome
    • Schmulson, M.J.; Valdovinos, M.A.; Milke, P. Chili pepper and rectal hyperalgesia in irritable bowel syndrome. Am. J. Gastroen-terol., 2003, 98(5), 1214-1215.
    • (2003) Am. J. Gastroen-terol , vol.98 , Issue.5 , pp. 1214-1215
    • Schmulson, M.J.1    Valdovinos, M.A.2    Milke, P.3
  • 206
    • 46349106355 scopus 로고    scopus 로고
    • Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
    • Akbar, A.; Yiangou, Y.; Facer, P.; Walters, J.R.; Anand, P.; Ghosh, S. Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain. Gut, 2008, 57(7), 923-929.
    • (2008) Gut , vol.57 , Issue.7 , pp. 923-929
    • Akbar, A.1    Yiangou, Y.2    Facer, P.3    Walters, J.R.4    Anand, P.5    Ghosh, S.6
  • 207
    • 67349110511 scopus 로고    scopus 로고
    • Involvement of the transient receptor potential vanilloid 1 (TRPV1) in the development of acute visceral hyperalgesia during colorectal distension in rats
    • Ravnefjord, A.; Brusberg, M.; Kang, D.; Bauer, U.; Larsson, H.; Lindström, E.; Martinez, V. Involvement of the transient receptor potential vanilloid 1 (TRPV1) in the development of acute visceral hyperalgesia during colorectal distension in rats. Eur. J. Pharmacol., 2009, 611(1-3), 85-91.
    • (2009) Eur. J. Pharmacol , vol.611 , Issue.1-3 , pp. 85-91
    • Ravnefjord, A.1    Brusberg, M.2    Kang, D.3    Bauer, U.4    Larsson, H.5    Lindström, E.6    Martinez, V.7
  • 208
    • 34547457004 scopus 로고    scopus 로고
    • The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis
    • Liddle, R.A. The role of Transient Receptor Potential Vanilloid 1 (TRPV1) channels in pancreatitis. Biochim. Biophys. Acta., 2007, 1772(8), 869-878.
    • (2007) Biochim. Biophys. Acta , vol.1772 , Issue.8 , pp. 869-878
    • Liddle, R.A.1
  • 210
    • 33846807748 scopus 로고    scopus 로고
    • Transient receptor potential cation channels in disease
    • Nilius, B.; Owsianik, G.; Voets, T.; Peters, JA. Transient receptor potential cation channels in disease. Physiol. Rev., 2007, 87(1), 165-217.
    • (2007) Physiol. Rev , vol.87 , Issue.1 , pp. 165-217
    • Nilius, B.1    Owsianik, G.2    Voets, T.3    Peters, J.A.4
  • 211
    • 0037309871 scopus 로고    scopus 로고
    • Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency
    • Chan, C.L.; Facer, P.; Davis, J.B.; Smith, G.D.; Egerton, J.; Boun-tra, C.; Williams, N.S.; Anand, P. Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency. Lancet, 2003, 361(9355), 385-391.
    • (2003) Lancet , vol.361 , Issue.9355 , pp. 385-391
    • Chan, C.L.1    Facer, P.2    Davis, J.B.3    Smith, G.D.4    Egerton, J.5    Boun-Tra, C.6    Williams, N.S.7    Anand, P.8
  • 212
    • 0034760415 scopus 로고    scopus 로고
    • Novel capsaicin (VR1) and purinergic (P2X3) receptors in Hirschsprung's intestine
    • Facer, P.; Knowles, C.H.; Tam, P.K.; Ford, A.P.; Dyer, N.; Baecker, P.A.; Anand, P. Novel capsaicin (VR1) and purinergic (P2X3) receptors in Hirschsprung's intestine. J. Pediatr. Surg., 2001, 36(11), 1679-1684.
    • (2001) J. Pediatr. Surg , vol.36 , Issue.11 , pp. 1679-1684
    • Facer, P.1    Knowles, C.H.2    Tam, P.K.3    Ford, A.P.4    Dyer, N.5    Baecker, P.A.6    Anand, P.7
  • 213
    • 34547420154 scopus 로고    scopus 로고
    • TRPs in bladder diseases
    • Birder, L.A. TRPs in bladder diseases. Biochim. Biophys. Acta., 2007, 1772(8), 879-884.
    • (2007) Biochim. Biophys. Acta , vol.1772 , Issue.8 , pp. 879-884
    • Birder, L.A.1
  • 215
    • 0037382033 scopus 로고    scopus 로고
    • Involvement of primary afferent nerves after abdominal irradiation: Consequences on ileal contractile activity and inflammatory mediator release in the rat
    • Linard, C.; Marquette, C.; Strup, C.; Aigueperse, J.; Mathe, D. Involvement of primary afferent nerves after abdominal irradiation: consequences on ileal contractile activity and inflammatory mediator release in the rat. Dig. Dis. Sci., 2003, 48(4), 688-697.
    • (2003) Dig. Dis. Sci , vol.48 , Issue.4 , pp. 688-697
    • Linard, C.1    Marquette, C.2    Strup, C.3    Aigueperse, J.4    Mathe, D.5
  • 217
    • 3242772894 scopus 로고    scopus 로고
    • Intravesical resinifera-toxin decreases spinal c-fos expression and increases bladder volume to reflex micturition in rats with chronic inflamed urinary bladders
    • Dinis, P.; Charrua, A.; Avelino, A.; Cruz, F. Intravesical resinifera-toxin decreases spinal c-fos expression and increases bladder volume to reflex micturition in rats with chronic inflamed urinary bladders. B.J.U. Int., 2004, 94(1), 153-157.
    • (2004) B.J.U. Int , vol.94 , Issue.1 , pp. 153-157
    • Dinis, P.1    Charrua, A.2    Avelino, A.3    Cruz, F.4
  • 218
    • 35148889475 scopus 로고    scopus 로고
    • Resiniferatoxin and botulinum toxin type A for treatment of lower urinary tract symptoms
    • Cruz, F.; Dinis, P. Resiniferatoxin and botulinum toxin type A for treatment of lower urinary tract symptoms. Neurourol. Urodyn., 2007, 26(6 Suppl), 920-927.
    • (2007) Neurourol. Urodyn , vol.26 , Issue.6 SUPPL , pp. 920-927
    • Cruz, F.1    Dinis, P.2
  • 219
    • 0031786527 scopus 로고    scopus 로고
    • Intravesical resiniferatoxin for the treatment of detrusor hyperre-flexia refractory to capsaicin in patients with chronic spinal cord diseases
    • Lazzeri, M.; Spinelli, M.; Beneforti, P.; Zanollo, A.; Turini, D. Intravesical resiniferatoxin for the treatment of detrusor hyperre-flexia refractory to capsaicin in patients with chronic spinal cord diseases. Scand. J. Urol. Nephrol, 1998, 32(5), 331-334.
    • (1998) Scand. J. Urol. Nephrol , vol.32 , Issue.5 , pp. 331-334
    • Lazzeri, M.1    Spinelli, M.2    Beneforti, P.3    Zanollo, A.4    Turini, D.5
  • 220
    • 0342437490 scopus 로고    scopus 로고
    • Suppression of bladder hyperreflexia by intravesical resiniferatoxin
    • Cruz, F.; Guimaraes, M.; Silva, C; Reis, M. Suppression of bladder hyperreflexia by intravesical resiniferatoxin. Lancet, 1997, 350(9078), 640-641.
    • (1997) Lancet , vol.350 , Issue.9078 , pp. 640-641
    • Cruz, F.1    Guimaraes, M.2    Silva, C.3    Reis, M.4
  • 221
    • 0036238329 scopus 로고    scopus 로고
    • Vanilloid receptor and detrusor instability
    • Cruz, F. Vanilloid receptor and detrusor instability. Urology, 2002, 59(5 Suppl 1), 51-60
    • (2002) Urology , vol.59 , Issue.5 SUPPL 1 , pp. 51-60
    • Cruz, F.1
  • 223
    • 33745281695 scopus 로고    scopus 로고
    • Therapeutic effect of multiple resiniferatoxin intravesical instillations in patients with refractory detrusor overactivity: A randomized, double-blind, placebo controlled study
    • Kuo, H.C.; Liu, H.T.; Yang, W.C. Therapeutic effect of multiple resiniferatoxin intravesical instillations in patients with refractory detrusor overactivity: a randomized, double-blind, placebo controlled study. J. Urol, 2006, 176(2), 641-645.
    • (2006) J. Urol , vol.176 , Issue.2 , pp. 641-645
    • Kuo, H.C.1    Liu, H.T.2    Yang, W.C.3
  • 224
    • 24644449231 scopus 로고    scopus 로고
    • Urodynamic effect of intravesical resiniferatoxin in patients with neurogenic detrusor overactivity of spinal origin: Results of a double-blind randomized placebo-controlled trial
    • Silva, C; Silva, J.; Ribeiro, M.J.; Avelino, A.; Cruz, F. Urodynamic effect of intravesical resiniferatoxin in patients with neurogenic detrusor overactivity of spinal origin: results of a double-blind randomized placebo-controlled trial. Eur. Urol, 2005, 48(4), 650-655.
    • (2005) Eur. Urol , vol.48 , Issue.4 , pp. 650-655
    • Silva, C.1    Silva, J.2    Ribeiro, M.J.3    Avelino, A.4    Cruz, F.5
  • 225
    • 2342419444 scopus 로고    scopus 로고
    • Intravesical resiniferatoxin for patients with neurogenic detrusor overactivity
    • Watanabe, T.; Yokoyama, T.; Sasaki, K.; Nozaki, K.; Ozawa, H.; Kumon, H. Intravesical resiniferatoxin for patients with neurogenic detrusor overactivity. Int. J. Urol., 2004, 11(4), 200-205.
    • (2004) Int. J. Urol , vol.11 , Issue.4 , pp. 200-205
    • Watanabe, T.1    Yokoyama, T.2    Sasaki, K.3    Nozaki, K.4    Ozawa, H.5    Kumon, H.6
  • 226
    • 1242306589 scopus 로고    scopus 로고
    • Intravesical vanil-loids and neurogenic incontinence: Ten years experience
    • Lazzeri, M.; Spinelli, M.; Zanollo, A.; Turini, D. Intravesical vanil-loids and neurogenic incontinence: ten years experience. Urol. Int., 2004, 72(2), 145-149.
    • (2004) Urol. Int , vol.72 , Issue.2 , pp. 145-149
    • Lazzeri, M.1    Spinelli, M.2    Zanollo, A.3    Turini, D.4
  • 227
    • 3142624513 scopus 로고    scopus 로고
    • Intravesical therapy options for neurogenic detrusor overactivity
    • Reitz, A.; Schurch, B. Intravesical therapy options for neurogenic detrusor overactivity. Spinal Cord, 2004, 42(5), 267-272.
    • (2004) Spinal Cord , vol.42 , Issue.5 , pp. 267-272
    • Reitz, A.1    Schurch, B.2
  • 228
    • 10744223250 scopus 로고    scopus 로고
    • Intravesical capsaicin versus resiniferatoxin for the treatment of detrusor hyperreflexia in spinal cord injured patients: A double-blind, randomized, controlled study
    • De Seze, M.; Wiart, L.; de Seze, M.P.; Soyeur, L.; Dosque, J.P.; Blajezewski, S.; Moore, N.; Brochet, B.; Mazaux, J.M., Barat, M.; Joseph, P.A. Intravesical capsaicin versus resiniferatoxin for the treatment of detrusor hyperreflexia in spinal cord injured patients: a double-blind, randomized, controlled study. J. Urol., 2004, 171(1), 251-255.
    • (2004) J. Urol , vol.171 , Issue.1 , pp. 251-255
    • de Seze, M.1    Wiart, L.2    de Seze, M.P.3    Soyeur, L.4    Dosque, J.P.5    Blajezewski, S.6    Moore, N.7    Brochet, B.8    Mazaux, J.M.9    Barat, M.10    Joseph, P.A.11
  • 229
    • 56349119753 scopus 로고    scopus 로고
    • Intrathecal delivery of resiniferatoxin (RTX) reduces detrusor overactivity and spinal expression of TRPV1 in spinal cord injured animals
    • Cruz, CD.; Charrua, A.; Vieira, E.; Valente, J.; Avelino, A.; Cruz, F. Intrathecal delivery of resiniferatoxin (RTX) reduces detrusor overactivity and spinal expression of TRPV1 in spinal cord injured animals. Exp. Neurol, 2008, 214(2), 301-308.
    • (2008) Exp. Neurol , vol.214 , Issue.2 , pp. 301-308
    • Cruz, C.D.1    Charrua, A.2    Vieira, E.3    Valente, J.4    Avelino, A.5    Cruz, F.6
  • 230
    • 57149095621 scopus 로고    scopus 로고
    • GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models
    • Charrua, A.; Cruz, CD.; Narayanan, S.; Gharat, L.; Gullapalli, S.; Cruz, F.; Avelino, A. GRC-6211, a new oral specific TRPV1 antagonist, decreases bladder overactivity and noxious bladder input in cystitis animal models. J. Urol., 2009, 181(1), 379-386.
    • (2009) J. Urol , vol.181 , Issue.1 , pp. 379-386
    • Charrua, A.1    Cruz, C.D.2    Narayanan, S.3    Gharat, L.4    Gullapalli, S.5    Cruz, F.6    Avelino, A.7
  • 231
    • 27244448170 scopus 로고    scopus 로고
    • Prospective randomized, double-blind study of safety and toler-ability of intravesical resiniferatoxin (RTX) in interstitial cystitis (IC)
    • Chen, T.Y.; Corcos, J.; Camel, M.; Ponsot, Y.; Tule, M. Prospective, randomized, double-blind study of safety and toler-ability of intravesical resiniferatoxin (RTX) in interstitial cystitis (IC). Int. Urogynecol. J. Pelvic. Floor. Dysfunct, 2005, 16(4), 293-297.
    • (2005) Int. Urogynecol. J. Pelvic. Floor. Dysfunct , vol.16 , Issue.4 , pp. 293-297
    • Chen, T.Y.1    Corcos, J.2    Camel, M.3    Ponsot, Y.4    Tule, M.5
  • 232
    • 33646571242 scopus 로고    scopus 로고
    • Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain
    • Cristino, L.; de Petrocellis, L.; Pryce, G.; Baker, D.; Guglielmotti, V.; Di Marzo, V. Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience, 2006, 139(4), 1405-1415
    • (2006) Neuroscience , vol.139 , Issue.4 , pp. 1405-1415
    • Cristino, L.1    de Petrocellis, L.2    Pryce, G.3    Baker, D.4    Guglielmotti, V.5    Di Marzo, V.6
  • 233
    • 40249111593 scopus 로고    scopus 로고
    • TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons
    • Gibson, H.E.; Page, R.S.; Van Hook, M.J.; Kauer, J.A. TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons. Neuron, 2008, 57(5), 746-759.
    • (2008) Neuron , vol.57 , Issue.5 , pp. 746-759
    • Gibson, H.E.1    Page, R.S.2    van Hook, M.J.3    Kauer, J.A.4
  • 234
    • 0036460445 scopus 로고    scopus 로고
    • Inhibition of GABAergic neurotransmission in the ventral tegmental area by cannabinoids
    • Szabo, B.; Siemes, S.; Wallmichrath, I. Inhibition of GABAergic neurotransmission in the ventral tegmental area by cannabinoids. Eur. J. Neurosci. 2002, 15(12), 2057-2061.
    • (2002) Eur. J. Neurosci , vol.15 , Issue.12 , pp. 2057-2061
    • Szabo, B.1    Siemes, S.2    Wallmichrath, I.3
  • 235
    • 0037486951 scopus 로고    scopus 로고
    • Vanilloid receptors in hearing: Altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti
    • Zheng, J.; Dai, C; Steyger, P.S.; Kim, Y.; Vass, Z.; Ren, T.; Nut-tall, A.L. Vanilloid receptors in hearing: altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti. J. Neurophysiol, 2003, 90(1), 444-455.
    • (2003) J. Neurophysiol , vol.90 , Issue.1 , pp. 444-455
    • Zheng, J.1    Dai, C.2    Steyger, P.S.3    Kim, Y.4    Vass, Z.5    Ren, T.6    Nut-Tall, A.L.7
  • 236
    • 1542351164 scopus 로고    scopus 로고
    • Co-localization of the vanilloid capsaicin receptor and substance P in sensory nerve fibers innervating cochlear and vertebrobasilar arteries
    • Vass, Z.; Dai, C.F.; Steyger, P.S.; Jancso, G.; Trune, D.R.; Nuttall, A.L. Co-localization of the vanilloid capsaicin receptor and substance P in sensory nerve fibers innervating cochlear and vertebrobasilar arteries. Neuroscience, 2004, 124(4), 919-927.
    • (2004) Neuroscience , vol.124 , Issue.4 , pp. 919-927
    • Vass, Z.1    Dai, C.F.2    Steyger, P.S.3    Jancso, G.4    Trune, D.R.5    Nuttall, A.L.6
  • 237
    • 63349100394 scopus 로고    scopus 로고
    • Hot flash: TRPV channels in the brain
    • Kauer, J.A.; Gibson, H.E. Hot flash: TRPV channels in the brain. Trends Neurosci., 2009, 32(4), 215-224.
    • (2009) Trends Neurosci , vol.32 , Issue.4 , pp. 215-224
    • Kauer, J.A.1    Gibson, H.E.2
  • 238
    • 0034307478 scopus 로고    scopus 로고
    • New perspectives on enigmatic vanilloid receptors
    • Szallasi, A.; Di Marzo, V. New perspectives on enigmatic vanilloid receptors. Trends Neurosci., 2000, 23(10), 491-497.
    • (2000) Trends Neurosci , vol.23 , Issue.10 , pp. 491-497
    • Szallasi, A.1    Di Marzo, V.2
  • 241
    • 1242296878 scopus 로고    scopus 로고
    • Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat
    • Lewinter, R.D.; Skinner, K. Julius, D.; Basbaum, A.I. Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J. Comp. Neurol, 2004, 470(4), 400-408.
    • (2004) J. Comp. Neurol , vol.470 , Issue.4 , pp. 400-408
    • Lewinter, R.D.1    Skinner, K.2    Julius, D.3    Basbaum, A.I.4
  • 242
    • 38049058793 scopus 로고    scopus 로고
    • Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) im-munoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat
    • Lewinter, R.D.; Scherrer, G.; Basbaum, A.I. Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) im-munoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat. Neuroscience, 2008, 151(1), 164-173.
    • (2008) Neuroscience , vol.151 , Issue.1 , pp. 164-173
    • Lewinter, R.D.1    Scherrer, G.2    Basbaum, A.I.3
  • 244
    • 77649274710 scopus 로고    scopus 로고
    • Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture
    • Bai, J.Z.; Lipski, J. Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture. Neurotoxicology, 2010, 31(2), 204-214.
    • (2010) Neurotoxicology , vol.31 , Issue.2 , pp. 204-214
    • Bai, J.Z.1    Lipski, J.2
  • 245
    • 33749130615 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid subtype 1 mediates microglial cell death in vivo and in vitro via Ca2+-mediated mitochondrial damage and cytochromec release
    • Kim, S.R.; Kim, S.U.; Oh, U.; Jin, B.K. Transient receptor potential vanilloid subtype 1 mediates microglial cell death in vivo and in vitro via Ca2+-mediated mitochondrial damage and cytochromec release. J. Immunol, 2006, 177(7), 4322-4329
    • (2006) J. Immunol , vol.177 , Issue.7 , pp. 4322-4329
    • Kim, S.R.1    Kim, S.U.2    Oh, U.3    Jin, B.K.4
  • 246
    • 0035662685 scopus 로고    scopus 로고
    • The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice
    • Al-Hayani, A.; Wease, K.N.; Ross, R.A.; Pertwee, R.G.; Davies, S.N. The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. Neuropharmacology, 2001, 41(8), 1000-1005.
    • (2001) Neuropharmacology , vol.41 , Issue.8 , pp. 1000-1005
    • Al-Hayani, A.1    Wease, K.N.2    Ross, R.A.3    Pertwee, R.G.4    Davies, S.N.5
  • 247
    • 0037207070 scopus 로고    scopus 로고
    • Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition
    • Hájos, N.; Freund, T.F. Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition. Chem. Phys. Lipids, 2002, 121(1-2), 73-82.
    • (2002) Chem. Phys. Lipids , vol.121 , Issue.1-2 , pp. 73-82
    • Hájos, N.1    Freund, T.F.2
  • 248
    • 48149112620 scopus 로고    scopus 로고
    • Antis-tress effect of TRPV1 channel on synaptic plasticity and spatial memory
    • Li, H.B.; Mao, R.R.; Zhang, J.C.; Yang, Y.; Cao, J.; Xu, L. Antis-tress effect of TRPV1 channel on synaptic plasticity and spatial memory. Biol. Psychiatry, 2008, 64(4), 286-92.
    • (2008) Biol. Psychiatry , vol.64 , Issue.4 , pp. 286-292
    • Li, H.B.1    Mao, R.R.2    Zhang, J.C.3    Yang, Y.4    Cao, J.5    Xu, L.6
  • 249
    • 0036713282 scopus 로고    scopus 로고
    • Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro
    • Marinelli, S.; Vaughan, C.W.; Christie, M.J.; Connor, M. Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus in vitro. J. Physiol, 2002, 543(Pt 2), 531-540.
    • (2002) J. Physiol , vol.543 , Issue.Pt 2 , pp. 531-540
    • Marinelli, S.1    Vaughan, C.W.2    Christie, M.J.3    Connor, M.4
  • 250
    • 0037996964 scopus 로고    scopus 로고
    • Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors
    • Marinelli, S.; Di Marzo, V.; Berretta, N.; Matias, I.; Maccarrone, M.; Bernardi, G.; Mercuri, N.B. Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. J. Neurosci., 2003, 23(8), 3136-3144.
    • (2003) J. Neurosci , vol.23 , Issue.8 , pp. 3136-3144
    • Marinelli, S.1    Di Marzo, V.2    Berretta, N.3    Matias, I.4    Maccarrone, M.5    Bernardi, G.6    Mercuri, N.B.7
  • 252
    • 30344474717 scopus 로고    scopus 로고
    • Regulation of circuits and excitability: Implications for epileptogenesis
    • Hablitz, J.J. Regulation of circuits and excitability: implications for epileptogenesis. Epilepsy Curr., 2004, 4(4), 151-153
    • (2004) Epilepsy Curr , vol.4 , Issue.4 , pp. 151-153
    • Hablitz, J.J.1
  • 253
    • 21344439081 scopus 로고    scopus 로고
    • Fatty acid amidohydrolase in human neocortex-activity in epileptic and non-epileptic brain tissue and inhibition by putative endocan-nabinoids
    • Steffens, M.; Schulze-Bonhage A.; Surges, R.; Feuerstein, T.J. Fatty acid amidohydrolase in human neocortex-activity in epileptic and non-epileptic brain tissue and inhibition by putative endocan-nabinoids. Neurosci. Lett, 2005, 385(1), 13-17.
    • (2005) Neurosci. Lett , vol.385 , Issue.1 , pp. 13-17
    • Steffens, M.1    Schulze-Bonhage, A.2    Surges, R.3    Feuerstein, T.J.4
  • 254
    • 0038545287 scopus 로고    scopus 로고
    • Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase
    • Clement, A.B.; Hawkins, E.G.; Lichtman, A.H.; Cravatt, B.F. Increased seizure susceptibility and proconvulsant activity of anandamide in mice lacking fatty acid amide hydrolase. J. Neurosci. 2003, 23(9), 3916-3923.
    • (2003) J. Neurosci , vol.23 , Issue.9 , pp. 3916-3923
    • Clement, A.B.1    Hawkins, E.G.2    Lichtman, A.H.3    Cravatt, B.F.4
  • 257
    • 64749108287 scopus 로고    scopus 로고
    • TRPV1: A potential target for antiepileptogenesis
    • Fu, M.; Xie, Z.; Zuo, H. TRPV1: a potential target for antiepileptogenesis. Med. Hypotheses, 2009, 73(1), 100-102.
    • (2009) Med. Hypotheses , vol.73 , Issue.1 , pp. 100-102
    • Fu, M.1    Xie, Z.2    Zuo, H.3
  • 258
    • 33845347420 scopus 로고    scopus 로고
    • Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping
    • Singewald, N. Altered brain activity processing in high-anxiety rodents revealed by challenge paradigms and functional mapping. Neurosci. Biobehav. Rev, 2007, 31(1), 18-40.
    • (2007) Neurosci. Biobehav. Rev , vol.31 , Issue.1 , pp. 18-40
    • Singewald, N.1
  • 259
    • 0037441837 scopus 로고    scopus 로고
    • Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxio-genic drugs
    • Singewald, N.; Salchner, P.; Sharp, T. Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxio-genic drugs. Biol. Psychiatry, 2003, 53(4), 275-283.
    • (2003) Biol. Psychiatry , vol.53 , Issue.4 , pp. 275-283
    • Singewald, N.1    Salchner, P.2    Sharp, T.3
  • 260
    • 0034124204 scopus 로고    scopus 로고
    • Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry
    • Singewald, N.; Sharp, T. Neuroanatomical targets of anxiogenic drugs in the hindbrain as revealed by Fos immunocytochemistry. Neuroscience, 2000, 98(4), 759-770.
    • (2000) Neuroscience , vol.98 , Issue.4 , pp. 759-770
    • Singewald, N.1    Sharp, T.2
  • 262
    • 33846636000 scopus 로고    scopus 로고
    • Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice
    • Marsch, R.; Foeller, E.; Rammes, G.; Bunck, M.; Kössl, M.; Hols-boer, F.; Zieglgänsberger, W.; Landgraf, R.; Lutz, B.; Wotjak, C.T. Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice. J. Neurosci., 2007, 27(4), 832-839.
    • (2007) J. Neurosci , vol.27 , Issue.4 , pp. 832-839
    • Marsch, R.1    Foeller, E.2    Rammes, G.3    Bunck, M.4    Kössl, M.5    Hols-Boer, F.6    Zieglgänsberger, W.7    Landgraf, R.8    Lutz, B.9    Wotjak, C.T.10
  • 264
    • 33846869741 scopus 로고    scopus 로고
    • Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray
    • Moreira, F.A.; Aguiar, D.C.; Guimarães, F.S. Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. Neuropharmacology, 2007, 52(3), 958-965.
    • (2007) Neuropharmacology , vol.52 , Issue.3 , pp. 958-965
    • Moreira, F.A.1    Aguiar, D.C.2    Guimarães, F.S.3
  • 265
    • 58949098416 scopus 로고    scopus 로고
    • Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray
    • Terzian, A.L.; Aguiar, D.; Guimarães, F.; Moreira, F.A. Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray. Eur. Neuropsychopharmacol., 2009, 19(3), 188-195.
    • (2009) Eur. Neuropsychopharmacol , vol.19 , Issue.3 , pp. 188-195
    • Terzian, A.L.1    Aguiar, D.2    Guimarães, F.3    Moreira, F.A.4
  • 266
    • 71549171421 scopus 로고    scopus 로고
    • Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids
    • Campos, A.C.; Guimarães, F.S. Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids. Prog. Neuropsychopharmacol. Biol. Psychiatry, 2009, 33(8), 1517-1521.
    • (2009) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.33 , Issue.8 , pp. 1517-1521
    • Campos, A.C.1    Guimarães, F.S.2
  • 267
    • 52449111516 scopus 로고    scopus 로고
    • Attenuation of anxiety-related behaviour after the antagonism of transient receptor potential vanilloid type 1 channels in the rat ventral hippocampus
    • Santos, C.J.; Stern, C.A.; Bertoglio, L.J. Attenuation of anxiety-related behaviour after the antagonism of transient receptor potential vanilloid type 1 channels in the rat ventral hippocampus. Behav. Pharmacol, 2008, 19(4), 357-360.
    • (2008) Behav. Pharmacol , vol.19 , Issue.4 , pp. 357-360
    • Santos, C.J.1    Stern, C.A.2    Bertoglio, L.J.3
  • 268
    • 67649998667 scopus 로고    scopus 로고
    • Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats
    • Aguiar, D.C.; Terzian, A.L.; Guimarães, F.S.; Moreira, F.A. Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats. Psychopharmacology (Berl), 2009, 205(2), 217-225.
    • (2009) Psychopharmacology (Berl) , vol.205 , Issue.2 , pp. 217-225
    • Aguiar, D.C.1    Terzian, A.L.2    Guimarães, F.S.3    Moreira, F.A.4
  • 269
    • 69749094153 scopus 로고    scopus 로고
    • Altered responses of dopamine D3 receptor knockout mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems
    • Micale, V.; Cristino, L.; Tamburella, A.; Petrosino, S.; Leggio, G.M.; Drago, F.; Di Marzo, V. Altered responses of dopamine D3 receptor knockout mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems. Neurobiol. Dis., 2009, 36(1), 70-80.
    • (2009) Neurobiol. Dis , vol.36 , Issue.1 , pp. 70-80
    • Micale, V.1    Cristino, L.2    Tamburella, A.3    Petrosino, S.4    Leggio, G.M.5    Drago, F.6    Di Marzo, V.7
  • 270
    • 51349150614 scopus 로고    scopus 로고
    • Interactions between CB (1) receptors and TRPV1 channels mediated by 12-HPETE are cytotoxic to mesencephalic dopaminergic neurons
    • Kim, S.R.; Bok, E.; Chung, Y.C.; Chung, E.S.; Jin, B.K. Interactions between CB (1) receptors and TRPV1 channels mediated by 12-HPETE are cytotoxic to mesencephalic dopaminergic neurons. Br. J. Pharmacol, 2008, 155(2), 253-264.
    • (2008) Br. J. Pharmacol , vol.155 , Issue.2 , pp. 253-264
    • Kim, S.R.1    Bok, E.2    Chung, Y.C.3    Chung, E.S.4    Jin, B.K.5
  • 271
    • 12744280682 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro
    • Kim, S.R.; Lee, D.Y.; Chung, E.S.; Oh, U.T.; Kim, S.U.; Jin, B.K. Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro. J. Neurosci., 2005, 25(3), 662-671.
    • (2005) J. Neurosci , vol.25 , Issue.3 , pp. 662-671
    • Kim, S.R.1    Lee, D.Y.2    Chung, E.S.3    Oh, U.T.4    Kim, S.U.5    Jin, B.K.6
  • 272
    • 80052192940 scopus 로고    scopus 로고
    • Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: Role of CB1 and TRPV1 receptors
    • Morgese, M.G.; Cassano, T.; Cuomo, V.; Giuffrida, A. Anti-dyskinetic effects of cannabinoids in a rat model of Parkinson's disease: role of CB1 and TRPV1 receptors. Exp. Neurol, 2008, 211(2), 334-338.
    • (2008) Exp. Neurol , vol.211 , Issue.2 , pp. 334-338
    • Morgese, M.G.1    Cassano, T.2    Cuomo, V.3    Giuffrida, A.4
  • 273
    • 33747061265 scopus 로고    scopus 로고
    • A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and re-serpine-treated rats
    • Lee, J.; Di Marzo, V.; Brotchie, J.M. A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and re-serpine-treated rats. Neuropharmacology, 2006, 51(3), 557-565.
    • (2006) Neuropharmacology , vol.51 , Issue.3 , pp. 557-565
    • Lee, J.1    Di Marzo, V.2    Brotchie, J.M.3
  • 274
    • 33644615315 scopus 로고    scopus 로고
    • Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdo-paminergia-related hyperactivity: Therapeutic implications
    • Tzavara, E.T.; Li, D.L.; Moutsimilli, L.; Bisogno, T.; Di Marzo, V.; Phebus, L.A.; Nomikos, G.G.; Giros, B. Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdo-paminergia-related hyperactivity: therapeutic implications. Biol. Psychiatry., 2006, 59(6), 508-515.
    • (2006) Biol. Psychiatry , vol.59 , Issue.6 , pp. 508-515
    • Tzavara, E.T.1    Li, D.L.2    Moutsimilli, L.3    Bisogno, T.4    Di Marzo, V.5    Phebus, L.A.6    Nomikos, G.G.7    Giros, B.8
  • 275
    • 17644367823 scopus 로고    scopus 로고
    • Activation of TRPV1 in the VTA excites dopa- minergic neurons and increases chemical- and noxious-induced do- pamine release in the nucleus accumbens
    • Marinelli, S.; Pascucci, T.; Bernardi, G.; Puglisi-Allegra, S.; Mercuri, N.B. Activation of TRPV1 in the VTA excites dopa- minergic neurons and increases chemical- and noxious-induced do- pamine release in the nucleus accumbens. Neuropsychopharmacology, 2005, 30(5), 864-870.
    • (2005) Neuropsychopharmacology , vol.30 , Issue.5 , pp. 864-870
    • Marinelli, S.1    Pascucci, T.2    Bernardi, G.3    Puglisi-Allegra, S.4    Mercuri, N.B.5
  • 276
    • 27144549707 scopus 로고    scopus 로고
    • Intrinsic sensory deprivation induced by neonatal cap-saicin treatment induces changes in rat brain and behaviour of possible relevance to schizophrenia
    • Newson, P.; Lynch-Frame, A.; Roach, R.; Bennett, S.; Carr, V.; Chahl, L.A. Intrinsic sensory deprivation induced by neonatal cap-saicin treatment induces changes in rat brain and behaviour of possible relevance to schizophrenia. Br. J. Pharmacol., 2005, 146(3), 408-418.
    • (2005) Br. J. Pharmacol , vol.146 , Issue.3 , pp. 408-418
    • Newson, P.1    Lynch-Frame, A.2    Roach, R.3    Bennett, S.4    Carr, V.5    Chahl, L.A.6
  • 277
    • 33644830973 scopus 로고    scopus 로고
    • Vanilloid VR1 receptor is involved in rimonabant-induced neuro-protection
    • Pegorini, S.; Zani, A.; Braida, D.; Guerini-Rocco, C.; Sala, M. Vanilloid VR1 receptor is involved in rimonabant-induced neuro-protection. Br. J. Pharmacol., 2006, 147(5), 552-559.
    • (2006) Br. J. Pharmacol , vol.147 , Issue.5 , pp. 552-559
    • Pegorini, S.1    Zani, A.2    Braida, D.3    Guerini-Rocco, C.4    Sala, M.5
  • 278
    • 37249040918 scopus 로고    scopus 로고
    • Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways
    • Starowicz, K.; Maione, S.; Cristino, L.; Palazzo, E. Marabese, I.; Rossi, F.; De Novellis, V.; Di Marzo, V. Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways. J. Neurosci., 2007, 27(50), 13739-13749.
    • (2007) J. Neurosci , vol.27 , Issue.50 , pp. 13739-13749
    • Starowicz, K.1    Maione, S.2    Cristino, L.3    Palazzo, E.4    Marabese, I.5    Rossi, F.6    de Novellis, V.7    Di Marzo, V.8
  • 279
    • 0036603005 scopus 로고    scopus 로고
    • Chronic pain and medullary descending facilitation
    • Porreca F.; Ossipov, M.H.; Gebhart, G.F. Chronic pain and medullary descending facilitation. Trends Neurosci., 2002, 25(6), 319-325.
    • (2002) Trends Neurosci , vol.25 , Issue.6 , pp. 319-325
    • Porreca, F.1    Ossipov, M.H.2    Gebhart, G.F.3
  • 280
    • 26244441323 scopus 로고    scopus 로고
    • Spinal and supraspinal contributions to central sensitization in peripheral neuropathy
    • Suzuki, R.; Dickenson, A. Spinal and supraspinal contributions to central sensitization in peripheral neuropathy. Neurosignals, 2005, 14(4), 175-181.
    • (2005) Neurosignals , vol.14 , Issue.4 , pp. 175-181
    • Suzuki, R.1    Dickenson, A.2
  • 281
    • 30744466202 scopus 로고    scopus 로고
    • Capsaicin-sensitive sensory neurons regulate myocardial function and gene expression pattern of rat hearts: A DNA microarray study
    • Zvara, A.; Bencsik, P.; Fodor, G.; Csont, T.; Hackler, L.; Dux, M.; Fürst, S.; Jancsó, G.; Puskás, L.G.; Ferdinandy, P. Capsaicin-sensitive sensory neurons regulate myocardial function and gene expression pattern of rat hearts: a DNA microarray study. FASEB J., 2006, 20(1), 160-162.
    • (2006) FASEB J , vol.20 , Issue.1 , pp. 160-162
    • Zvara, A.1    Bencsik, P.2    Fodor, G.3    Csont, T.4    Hackler, L.5    Dux, M.6    Fürst, S.7    Jancsó, G.8    Puskás, L.G.9    Ferdinandy, P.10
  • 282
    • 11444252556 scopus 로고    scopus 로고
    • Role of different proton-sensitive channels in releasing calcitonin gene-related peptide from isolated hearts of mutant mice
    • Strecker, T.; Messlinger, K.; Weyand, M.; Reeh, P.W. Role of different proton-sensitive channels in releasing calcitonin gene-related peptide from isolated hearts of mutant mice. Cardiovasc. Res., 2005, 65(2), 405-410.
    • (2005) Cardiovasc. Res , vol.65 , Issue.2 , pp. 405-410
    • Strecker, T.1    Messlinger, K.2    Weyand, M.3    Reeh, P.W.4
  • 284
    • 0032713659 scopus 로고    scopus 로고
    • The effect of bradykinin and its antagonist on survival time after coronary artery occlusion in hypertensive rats
    • Abbas, S.A.; Sharma, J.N.; Yusof, A.P. The effect of bradykinin and its antagonist on survival time after coronary artery occlusion in hypertensive rats. Immunopharmacology, 1999, 44(1-2), 93-98.
    • (1999) Immunopharmacology , vol.44 , Issue.1-2 , pp. 93-98
    • Abbas, S.A.1    Sharma, J.N.2    Yusof, A.P.3
  • 288
    • 33748749808 scopus 로고    scopus 로고
    • Nociceptors in cardiovascular functions: Complex interplay as a result of cyclooxygenase inhibition
    • Premkumar, L.S.; Raisinghani, M. Nociceptors in cardiovascular functions: complex interplay as a result of cyclooxygenase inhibition. Mol. Pain, 2006, 2, 26.
    • (2006) Mol. Pain , vol.2 , pp. 26
    • Premkumar, L.S.1    Raisinghani, M.2
  • 289
    • 0030005087 scopus 로고    scopus 로고
    • The role of substance P in myocardial dysfunction during ischemia and reperfusion
    • Chiao, H.; Caldwell, R.W. The role of substance P in myocardial dysfunction during ischemia and reperfusion. Naunyn. Schmiede-bergs. Arch. Pharmacol., 1996, 353(4), 400-407.
    • (1996) Naunyn. Schmiede-bergs. Arch. Pharmacol , vol.353 , Issue.4 , pp. 400-407
    • Chiao, H.1    Caldwell, R.W.2
  • 290
    • 0023544918 scopus 로고
    • Participation of capsaicin-sensitive neurons in the cardiovascular effects of neurotensin in guinea pigs
    • Bachelard, H.; St-Pierre, S.; Rioux, F. Participation of capsaicin-sensitive neurons in the cardiovascular effects of neurotensin in guinea pigs. Peptides, 1987, 8(6), 1079-1087.
    • (1987) Peptides , vol.8 , Issue.6 , pp. 1079-1087
    • Bachelard, H.1    St-Pierre, S.2    Rioux, F.3
  • 292
    • 0030851865 scopus 로고    scopus 로고
    • Role of nitric oxide in the dilator actions of capsaicin-sensitive nerves in the rabbit coronary circulation
    • Mitchell, J.A.; Williams, F.M.; Williams, T.J.; Larkin, S.W. Role of nitric oxide in the dilator actions of capsaicin-sensitive nerves in the rabbit coronary circulation. Neuropeptides, 1997, 31(4), 333-338.
    • (1997) Neuropeptides , vol.31 , Issue.4 , pp. 333-338
    • Mitchell, J.A.1    Williams, F.M.2    Williams, T.J.3    Larkin, S.W.4
  • 294
    • 34548399410 scopus 로고    scopus 로고
    • TRPV1 gene knockout impairs preconditioning protection against myocardial injury in isolated perfused hearts in mice
    • Zhong, B.; Wang, D.H. TRPV1 gene knockout impairs preconditioning protection against myocardial injury in isolated perfused hearts in mice. Am. J. Physiol. Heart Circ. Physiol., 2007, 293(3), H1791-1798.
    • (2007) Am. J. Physiol. Heart Circ. Physiol , vol.293 , Issue.3 , pp. 1791-1798
    • Zhong, B.1    Wang, D.H.2
  • 295
    • 0032773307 scopus 로고    scopus 로고
    • Interplay between nitric oxide and CGRP by capsaicin in isolated guinea-pig heart
    • Oroszi, G.; Szilvassy, Z.; Nemeth, J.; Tosaki, A.; Szolcsanyi, J. Interplay between nitric oxide and CGRP by capsaicin in isolated guinea-pig heart. Pharmacol. Res., 1999, 40(2), 125-128.
    • (1999) Pharmacol. Res , vol.40 , Issue.2 , pp. 125-128
    • Oroszi, G.1    Szilvassy, Z.2    Nemeth, J.3    Tosaki, A.4    Szolcsanyi, J.5
  • 296
    • 0141476269 scopus 로고    scopus 로고
    • Cardiac vanilloid receptor-1-expressing afferent nerves and their role in the cardio-genic sympatheticreflex in rats
    • Zahner, M.R.; Li, D.P.; Chen, S.R.; Pan, H.L. Cardiac vanilloid receptor-1-expressing afferent nerves and their role in the cardio-genic sympatheticreflex in rats. J. Physiol., 2003, 551(Pt 2), 515-523.
    • (2003) J. Physiol , vol.551 , Issue.Pt 2 , pp. 515-523
    • Zahner, M.R.1    Li, D.P.2    Chen, S.R.3    Pan, H.L.4
  • 297
    • 54049122309 scopus 로고    scopus 로고
    • Femoral artery occlusion augments TRPV1-mediated sympathetic responsiveness
    • Xing, J.; Gao, Z.; Lu, J.; Sinoway, L.I.; Li, J. Femoral artery occlusion augments TRPV1-mediated sympathetic responsiveness. Am. J. Physiol. Heart. Circ. Physiol., 2008, 295(3), H1262-H1269.
    • (2008) Am. J. Physiol. Heart. Circ. Physiol , vol.295 , Issue.3 , pp. 1262-1269
    • Xing, J.1    Gao, Z.2    Lu, J.3    Sinoway, L.I.4    Li, J.5
  • 298
    • 33947188494 scopus 로고    scopus 로고
    • Neural control of blood pressure: Focusing on capsaicin-sensitive sensory nerves
    • Wang, Y.; Wang, D.H. Neural control of blood pressure: focusing on capsaicin-sensitive sensory nerves. Cardiovasc. Hematol. Disord. Drug Targets, 2007, 7(1), 37-46.
    • (2007) Cardiovasc. Hematol. Disord. Drug Targets , vol.7 , Issue.1 , pp. 37-46
    • Wang, Y.1    Wang, D.H.2
  • 299
    • 70349329587 scopus 로고    scopus 로고
    • The role of transient receptor potential channels in kidney disease
    • Woudenberg-Vrenken, T.E.; Bindels, R.J.; Hoenderop, J.G. The role of transient receptor potential channels in kidney disease. Nat. Rev. Nephrol., 2009, 5(8), 441-449.
    • (2009) Nat. Rev. Nephrol , vol.5 , Issue.8 , pp. 441-449
    • Woudenberg-Vrenken, T.E.1    Bindels, R.J.2    Hoenderop, J.G.3
  • 300
    • 49849087847 scopus 로고    scopus 로고
    • Deletion of transient receptor potential vanilloid type 1 receptors exaggerates renal damage in deoxycorticosterone acetate-salt hypertension
    • Wang, Y.; Babánková, D.; Huang, J.; Swain, G.M.; Wang, D.H. Deletion of transient receptor potential vanilloid type 1 receptors exaggerates renal damage in deoxycorticosterone acetate-salt hypertension. Hypertension, 2008, 52(2), 264-270.
    • (2008) Hypertension , vol.52 , Issue.2 , pp. 264-270
    • Wang, Y.1    Babánková, D.2    Huang, J.3    Swain, G.M.4    Wang, D.H.5
  • 301
    • 71449122654 scopus 로고    scopus 로고
    • Aggravated renal inflammatory responses in TRPV1 gene knockout mice subjected to DOCA-salt hypertension
    • Wang, Y.; Wang, D.H. Aggravated renal inflammatory responses in TRPV1 gene knockout mice subjected to DOCA-salt hypertension. Am. J. Physiol. Renal Physiol., 2009, 297(6), F1550-1559.
    • (2009) Am. J. Physiol. Renal Physiol , vol.297 , Issue.6 , pp. 1550-1559
    • Wang, Y.1    Wang, D.H.2
  • 302
    • 44649161719 scopus 로고    scopus 로고
    • Role of TRPV1 channels in renal haemodynam-ics and function in Dahl salt-sensitive hypertensive rats
    • Li, J.; Wang, D.H. Role of TRPV1 channels in renal haemodynam-ics and function in Dahl salt-sensitive hypertensive rats. Exp. Physiol., 2008, 93(8), 945-953.
    • (2008) Exp. Physiol , vol.93 , Issue.8 , pp. 945-953
    • Li, J.1    Wang, D.H.2
  • 303
    • 73349115260 scopus 로고    scopus 로고
    • Ablation of transient receptor potential vanilloid 1 abolishes endothelin-induced increases in afferent renal nerve activity: Mechanisms and functional significance
    • Xie, C.; Wang, D.H. Ablation of transient receptor potential vanilloid 1 abolishes endothelin-induced increases in afferent renal nerve activity: mechanisms and functional significance. Hypertension, 2009, 54(6), 1298-1305.
    • (2009) Hypertension , vol.54 , Issue.6 , pp. 1298-1305
    • Xie, C.1    Wang, D.H.2
  • 305
    • 63849335664 scopus 로고    scopus 로고
    • Preventive effect of SA13353 [1-[2-(1-adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea], a novel transient receptor potential vanilloid 1 agonist, on ische-mia/reperfusion-induced renal injury in rats
    • Ueda, K.; Tsuji, F.; Hirata, T.; Ueda, K.; Murai, M.; Aono, H.; Takaoka, M.; Matsumura, Y. Preventive effect of SA13353 [1-[2-(1-adamantyl)ethyl]-1-pentyl-3-[3-(4-pyridyl)propyl]urea], a novel transient receptor potential vanilloid 1 agonist, on ische-mia/reperfusion-induced renal injury in rats. J. Pharmacol. Exp. Ther., 2009, 329(1), 202-209.
    • (2009) J. Pharmacol. Exp. Ther , vol.329 , Issue.1 , pp. 202-209
    • Ueda, K.1    Tsuji, F.2    Hirata, T.3    Ueda, K.4    Murai, M.5    Aono, H.6    Takaoka, M.7    Matsumura, Y.8
  • 306
    • 55949124873 scopus 로고    scopus 로고
    • Preventive effect of TRPV1 agonists capsaicin and resiniferatoxin on ischemia/reperfusion-induced renal injury in rats
    • Ueda, K.; Tsuji, F.; Hirata, T.; Takaoka, M.; Matsumura, Y. Preventive effect of TRPV1 agonists capsaicin and resiniferatoxin on ischemia/reperfusion-induced renal injury in rats. J. Cardiovasc. Pharmacol., 2008, 51(5), 513-520.
    • (2008) J. Cardiovasc. Pharmacol , vol.51 , Issue.5 , pp. 513-520
    • Ueda, K.1    Tsuji, F.2    Hirata, T.3    Takaoka, M.4    Matsumura, Y.5
  • 307
    • 40849094326 scopus 로고    scopus 로고
    • Contribution of TRPV channels to osmosensory transduction, thirst, and vasopressin release
    • Sharif-Naeini, R.; Ciura, S.; Zhang, Z.; Bourque, C.W. Contribution of TRPV channels to osmosensory transduction, thirst, and vasopressin release. Kidney Int., 2008, 73(7), 811-815.
    • (2008) Kidney Int , vol.73 , Issue.7 , pp. 811-815
    • Sharif-Naeini, R.1    Ciura, S.2    Zhang, Z.3    Bourque, C.W.4
  • 308
    • 69549130906 scopus 로고    scopus 로고
    • TRPV1 receptor as a therapeutical target for the treatment of migraine
    • Shimizu, T. TRPV1 receptor as a therapeutical target for the treatment of migraine. Brain Nerve, 2009, 61(8), 949-956.
    • (2009) Brain Nerve , vol.61 , Issue.8 , pp. 949-956
    • Shimizu, T.1
  • 309
    • 34548850359 scopus 로고    scopus 로고
    • Distribution and origin of TRPV1 receptor-containing nerve fibers in the dura mater of rat
    • Shimizu, T.; Toriumi, H.; Sato, H.; Shibata, M.; Nagata, E.; Gotoh, K.; Suzuki, N. Distribution and origin of TRPV1 receptor-containing nerve fibers in the dura mater of rat. Brain Res., 2007, 1173, 84-91
    • (2007) Brain Res , vol.1173 , pp. 84-91
    • Shimizu, T.1    Toriumi, H.2    Sato, H.3    Shibata, M.4    Nagata, E.5    Gotoh, K.6    Suzuki, N.7
  • 310
    • 0242475143 scopus 로고    scopus 로고
    • Capsaicin-sensitive neurogenic sensory vasodilatation in the dura mater of the rat
    • Dux, M.; Sántha, P.; Jancsó, G. Capsaicin-sensitive neurogenic sensory vasodilatation in the dura mater of the rat. J. Physiol., 2003, 552(Pt 3), 859-867.
    • (2003) J. Physiol , vol.552 , Issue.Pt 3 , pp. 859-867
    • Dux, M.1    Sántha, P.2    Jancsó, G.3
  • 312
    • 35748947241 scopus 로고    scopus 로고
    • Emerging therapies for migraine
    • Goadsby, P.J. Emerging therapies for migraine. Nat. Clin. Pract. Neurol, 2007, 3(11), 610-619.
    • (2007) Nat. Clin. Pract. Neurol , vol.3 , Issue.11 , pp. 610-619
    • Goadsby, P.J.1
  • 313
    • 5144222469 scopus 로고    scopus 로고
    • Post-triptan era for the treatment of acute migraine
    • Goadsby, P.J. Post-triptan era for the treatment of acute migraine. Curr. Pain Headache Rep., 2004, 8(5), 393-398.
    • (2004) Curr. Pain Headache Rep , vol.8 , Issue.5 , pp. 393-398
    • Goadsby, P.J.1
  • 315
    • 30044452563 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide antagonists as treatments of migraine and other primary headaches
    • Goadsby, P. J. Calcitonin gene-related peptide antagonists as treatments of migraine and other primary headaches. Drugs, 2005, 65(18), 2557-2567.
    • (2005) Drugs , vol.65 , Issue.18 , pp. 2557-2567
    • Goadsby, P.J.1
  • 316
    • 1542351164 scopus 로고    scopus 로고
    • Co-localization of the vanilloid capsaicin receptor and substance P in sensory nerve fibers innervating cochlear and vertebrobasilar arteries
    • Vass, Z.; Dai, C.F.; Steyger, P.S.; Jancsó, G.; Trune, D.R.; Nuttall, A.L. Co-localization of the vanilloid capsaicin receptor and substance P in sensory nerve fibers innervating cochlear and vertebrobasilar arteries. Neuroscience, 2004, 124(4), 919-927.
    • (2004) Neuroscience , vol.124 , Issue.4 , pp. 919-927
    • Vass, Z.1    Dai, C.F.2    Steyger, P.S.3    Jancsó, G.4    Trune, D.R.5    Nuttall, A.L.6
  • 317
    • 33847370000 scopus 로고    scopus 로고
    • Immunotherapy of tumors with neuroimmune ligand capsaicin
    • Beltran, J.; Ghosh, A.K.; Basu, S. Immunotherapy of tumors with neuroimmune ligand capsaicin. J. Immunol.m 2007, 178(5), 3260-3264.
    • (2007) J. Immunol.m , vol.178 , Issue.5 , pp. 3260-3264
    • Beltran, J.1    Ghosh, A.K.2    Basu, S.3
  • 319
    • 70349443514 scopus 로고    scopus 로고
    • Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects
    • Light, A.R.; White, A.T.; Hughen, R.W.; Light, K.C. Moderate exercise increases expression for sensory, adrenergic, and immune genes in chronic fatigue syndrome patients but not in normal subjects. J. Pain, 2009, 10(10), 1099-1112
    • (2009) J. Pain , vol.10 , Issue.10 , pp. 1099-1112
    • Light, A.R.1    White, A.T.2    Hughen, R.W.3    Light, K.C.4
  • 320
    • 1342287208 scopus 로고    scopus 로고
    • Neurokinin-1 receptor antagonists protect mice from CD95- and tumor necrosis factor-alpha-mediated apoptotic liver damage
    • Bang, R.; Biburger, M.; Neuhuber, W.L.; Tiegs, G. Neurokinin-1 receptor antagonists protect mice from CD95- and tumor necrosis factor-alpha-mediated apoptotic liver damage. J. Pharmacol. Exp. Ther., 2004, 308(3), 1174-1180.
    • (2004) J. Pharmacol. Exp. Ther , vol.308 , Issue.3 , pp. 1174-1180
    • Bang, R.1    Biburger, M.2    Neuhuber, W.L.3    Tiegs, G.4
  • 323
    • 76749097281 scopus 로고    scopus 로고
    • Signaling in TRPV1 induced platelet activating factor (PAF) in human esophageal epithelial cells
    • Ma, J.; Harnett, K.M.; Behar, J.; Biancani, P.; Cao, W. Signaling in TRPV1 induced platelet activating factor (PAF) in human esophageal epithelial cells. Am. J. Physiol. Gastrointest. Liver. Physiol., 2010, 298(2), G233-240.
    • (2010) Am. J. Physiol. Gastrointest. Liver. Physiol , vol.298 , Issue.2 , pp. 233-240
    • Ma, J.1    Harnett, K.M.2    Behar, J.3    Biancani, P.4    Cao, W.5
  • 324
    • 60149113102 scopus 로고    scopus 로고
    • TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity
    • Shiba, T.; Maruyama, T.; Kurohane, K.; Iwasaki, Y.; Watanabe, T.; Imai, Y. TRPA1 and TRPV1 activation is a novel adjuvant effect mechanism in contact hypersensitivity. J. Neuroimmunol., 2009, 207(1-2), 66-74.
    • (2009) J. Neuroimmunol , vol.207 , Issue.1-2 , pp. 66-74
    • Shiba, T.1    Maruyama, T.2    Kurohane, K.3    Iwasaki, Y.4    Watanabe, T.5    Imai, Y.6
  • 326
    • 67650494652 scopus 로고    scopus 로고
    • TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms
    • Imamachi, N.; Park, G.H.; Lee, H.; Anderson, D.J.; Simon, M.I.; Basbaum, A.I.; Han, S.K. TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms. Proc. Natl. Acad. Sci. USA, 2009, 106(27), 11330-11335.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , Issue.27 , pp. 11330-11335
    • Imamachi, N.1    Park, G.H.2    Lee, H.3    Anderson, D.J.4    Simon, M.I.5    Basbaum, A.I.6    Han, S.K.7
  • 327
    • 65349175064 scopus 로고    scopus 로고
    • Transient receptor potential (TRP) channels and taste sensation
    • Ishimaru, Y.; Matsunami, H. Transient receptor potential (TRP) channels and taste sensation. J. Dent. Res., 2009, 88(3), 212-218.
    • (2009) J. Dent. Res , vol.88 , Issue.3 , pp. 212-218
    • Ishimaru, Y.1    Matsunami, H.2
  • 328
    • 0037486951 scopus 로고    scopus 로고
    • Vanilloid receptors in hearing: Altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti
    • Zheng, J.; Dai, C.; Steyger, P.S.; Kim, Y.; Vass, Z.; Ren, T.; Nuttall, A.L. Vanilloid receptors in hearing: altered cochlear sensitivity by vanilloids and expression of TRPV1 in the organ of corti. J. Neurophysiol., 2003, 90(1), 444-455.
    • (2003) J. Neurophysiol , vol.90 , Issue.1 , pp. 444-455
    • Zheng, J.1    Dai, C.2    Steyger, P.S.3    Kim, Y.4    Vass, Z.5    Ren, T.6    Nuttall, A.L.7
  • 329
    • 34447129412 scopus 로고    scopus 로고
    • Acoustic injury and TRPV1 expression in the cochlear spiral ganglion
    • Bauer, C.A.; Brozoski, T.J.; Myers, K.S. Acoustic injury and TRPV1 expression in the cochlear spiral ganglion. Int. Tinnitus J., 2007, 13(1), 21-28.
    • (2007) Int. Tinnitus J , vol.13 , Issue.1 , pp. 21-28
    • Bauer, C.A.1    Brozoski, T.J.2    Myers, K.S.3
  • 330
    • 58149395091 scopus 로고    scopus 로고
    • Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat
    • Mukherjea, D.; Jajoo, S.; Whitworth, C.; Bunch, J.R.; Turner, J.G.; Rybak, L.P.; Ramkumar, V. Short interfering RNA against transient receptor potential vanilloid 1 attenuates cisplatin-induced hearing loss in the rat. J. Neurosci., 2008, 28(49), 13056-13065.
    • (2008) J. Neurosci , vol.28 , Issue.49 , pp. 13056-13065
    • Mukherjea, D.1    Jajoo, S.2    Whitworth, C.3    Bunch, J.R.4    Turner, J.G.5    Rybak, L.P.6    Ramkumar, V.7
  • 331
    • 58149107126 scopus 로고    scopus 로고
    • Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway
    • Gunthorpe, M.J.; Chizh, B.A. Clinical development of TRPV1 antagonists: targeting a pivotal point in the pain pathway. Drug Discov. Today, 2009, 14(1-2), 56-67.
    • (2009) Drug Discov. Today , vol.14 , Issue.1-2 , pp. 56-67
    • Gunthorpe, M.J.1    Chizh, B.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.