Hot receptors in the brain

Molecular Pain

Volumn 2, Issue , 2006, Pages

  Steenland, Hendrik W ^a   Ko, Shanelle W ^a   Wu, Long Jun ^a   Zhuo, Min ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ANANDAMIDE; CANNABINOID 1 RECEPTOR; CAPSAICIN; FATTY ACID AMIDASE; RESINIFERATOXIN; VANILLOID RECEPTOR 1;

ANALGESIC ACTIVITY; BRAIN; BRAIN FUNCTION; BRAIN REGION; CHRONIC PAIN; CINGULATE GYRUS; DRUG RESEARCH; DRUG TARGETING; NERVE CELL PLASTICITY; NOCICEPTION; NONHUMAN; PERIPHERAL NERVE; PERIPHERAL NERVOUS SYSTEM; PREDICTION; PRIORITY JOURNAL; PRODUCT DEVELOPMENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REVIEW; SIGNAL PROCESSING; SPINAL CORD;

ANALGESICS, NON-NARCOTIC; ANIMALS; BRAIN; CAPSAICIN; HUMANS; PAIN; TRPV CATION CHANNELS;

EID: 34547925948     PISSN: 17448069     EISSN: None     Source Type: Journal    
DOI: 10.1186/1744-8069-2-34     Document Type: Review

References (65)

1. Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D: The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 1998, 21:531-543.
2. Davis JB, Gray J, Gunthorpe MJ, Hatcher JP, Davey PT, Overend P, Harries MH, Latcham J, Clapham C, Atkinson K, Hughes SA, Rance K, Grau E, Harper AJ, Pugh PL, Rogers DC, Bingham S, Randall A, Sheardown SA: Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 2000, 405:183-187.
3. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D: The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 1997, 389:816-824.
4. Tominaga M, Tominaga T: Structure and function of TRPV1. Pflugers Arch 2005, 451:143-150.
5. Tominaga M, Caterina MJ: Thermosensation and pain. J Neurobiol 2004, 61:3-12.
6. Nagy I, Santha P, Jancso G, Urban L: The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology. Eur J Pharmacol 2004, 500:351-369.
7. Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, Tognetto M, Petros TJ, Krey JF, Chu CJ, Miller JD, Davies SN, Geppetti P, Walker JM, Di Marzo V: An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci U S A 2002, 99:8400-8405.
8. Prescott ED, Julius D: A modular P1P2 binding site as a determinant of capsaicin receptor sensitivity. Science 2003, 300:1284-1288.
9. Smith GD, Gunthorpe MJ, Kelsell RE, Hayes PD, Reilly P, Facer P, Wright JE, Jerman JC, Walhin JP, Ooi L, Egerton J, Charles KJ, Smart D, Randall AD, Anand P, Davis JB: TRPV3 is a temperature-sensitive vanilloid receptor-like protein. Nature 2002, 418:186-190.
10. Vennekens R, Voets T, Bindels RJ, Droogmans G, Nilius B: Current understanding of mammalian TRP homologues. Cell Calcium 2002, 31:253-264.
11. Morenilla-Palao C, Planells-Cases R, Garcia-Sanz N, Ferrer-Montiel A: Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. J Biol Chem 2004, 279:25665-25672.
12. Caterina MJ, Leffler A, Malmberg AB, Martin WJ, Trafton J, Petersen-Zeitz KR, Koltzenburg M, Basbaum AI, Julius D: Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 2000, 288:306-313.
13. Sasamura T, Kuraishi Y. Peripheral and central actions of capsaicin and VR1 receptor. Jpn J Pharmacol 1999, 80:275-280.
14. Liapi A, Wood JN: Extensive co-localization and heteromultimer formation of the vanilloid receptor-like protein TRPV2 and the capsaicin receptor TRPV1 in the adult rat cerebral cortex. Eur J Neurosci 2005, 22:825-834.
15. Szallasi A, Nilsson S, Farkas-Szallasi T, Blumberg PM, Hokfelt T, Lundberg JM: Vanilloid (capsaicin) receptors in the rat: distribution in the brain, regional differences in the spinal cord, axonal transport to the periphery, and depletion by systemic vanilloid treatment. Brain Res 1995, 703:175-183.
16. Mezey E, Toth ZE, Cortright DN, Arzubi MK, Krause JE, Elde R, Guo A, Blumberg PM, Szallasi A: Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human. Proc Natl Acad Sci U S A 2000, 97:3655-3660.
17. Acs G, Palkovits M, Blumberg PM: Specific binding of [3H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypothalamus, reticular formation and ventral thalamus membrane preparations. Life Sci 1996, 59:1899-1908.
18. Roberts JC, Davis JB, Benham CD: [3H]Resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution. Brain Res 2004, 995:176-183.
19. Toth A, Boczan J, Kedei N, Lizanecz E, Bagi Z, Papp Z, Edes I, Csiba L, Blumberg PM: Expression and distribution of vanilloid receptor 1 (TRPV1) in the adult rat brain. Brain Res Mol Brain Res 2005, 135:162-168.
20. Szabo T, Biro T, Gonzalez AF, Palkovits M, Blumberg PM: Pharmacological characterization of vanilloid receptor located in the brain. Brain Res Mol Brain Res 2002, 98:51-57.
21. Sanchez JF, Krause JE, Cortright DN: The distribution and regulation of vanilloid receptor VR1 and VR1 5′ splice variant RNA expression in rat. Neuroscience 2001, 107:373-381.
22. Sasamura T, Sasaki M, Tohda C, Kuraishi Y: Existence of capsaicin-sensitive glutamatergic terminals in rat hypothalamus. Neuroreport 1998, 9:2045-2048.
23. Kim SR, Lee DY, Chung ES, Oh UT, Kim SU, Jin BK: Transient receptor potential vanilloid subtype 1 mediates cell death of mesencephalic dopaminergic neurons in vivo and in vitro. J Neurosci 2005, 25:662-671.
24. Millan MJ: Descending control of pain. Prog Neurobiol 2002, 66:355-474.
25. Millan MJ: The induction of pain: an integrative review. Prog Neurobiol 1999, 57:1-164.
26. Ji RR, Samad TA, Jin SX, Schmoll R, Woolf CJ: p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 2002, 36:57-68.
27. Koulchitsky SV, Azev OA, Gourine AV, Kulchitsky VA: Capsaicin-sensitive area in the ventral surface of the rat medulla. Neurosci Lett 1994, 182:129-132.
28. Osaka T, Lee TH, Kobayashi A, Inoue S, Kimura S: Thermogenesis mediated by a capsaicin-sensitive area in the ventrolateral medulla. Neuroreport 2000, 11:2425-2428.
29. Kobayashi A, Osaka T, Namba. Y, Inoue S, Lee TH, Kimura S: Capsaicin activates heat loss and heat production simultaneously and independently in rats. Am J Physiol 1998, 275:R92-8.
30. Hori T, Shibata M, Kiyohara T, Nakashima T, Asami A: Responses of anterior hypothalamic-preoptic thermosensitive neurons to locally applied capsaicin. Neuropharmacology 1988, 27:135-142.
31. Hori T: Capsaicin and central control of thermoregulation. Pharmacol Ther 1984, 26:389-416.
32. Watanabe T, Kawada T, Kurosawa M, Sato A, Iwai K: Adrenal sympathetic efferent nerve and catecholamine secretion excitation caused by capsaicin in rats. Am J Physiol 1988, 255:E23-7.
33. Renn CL, Dorsey SG: The physiology and processing of pain: a review. AACN Clin Issues 2005, 16:277-90; quiz 413-5.
34. Zhuo M, Gebhart GF: Facilitation and attenuation of a visceral nociceptive reflex from the rostroventral medulla in the rat. Gastroenterology 2002, 122:1007-1019.
35. Zhuo M, Sengupta JN, Gebhart GF: Biphasic modulation of spinal visceral nociceptive transmission from the rostroventral medial medulla in the rat. J Neurophysiol 2002, 87:2225-2236.
36. Zhuo M, Gebhart GF: Modulation of noxious and non-noxious spinal mechanical transmission from the rostral medial medulla in the rat. J Neurophysiol 2002, 88:2928-2941.
37. Gebhart GF: Descending modulation of pain. Neurosci Biobehav Rev 2004, 27:729-737.
38. Palazzo E, de Novellis V, Marabese I, Cuomo D, Rossi F, Berrino L, Maione S: Interaction between vanilloid and glutamate receptors in the central modulation of nociception. Eur J Pharmacol 2002, 439:69-75.
39. McGaraughty S, Chu KL, Bitner RS, Martino B, El Kouhen R, Han P, Nikkel AL, Burgard EC, Faltynek CR, Jarvis MF: Capsaicin infused into the PAG affects rat tail flick responses to noxious heat and alters neuronal firing in the RVM. J Neurophysiol 2003, 90:2702-2710.
40. Maione S, Bisogno T, de Novellis V, Palazzo E, Cristino L, Valenti M, Petrosino S, Guglielmotti V, Rossi F, Di Marzo V: Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors. J Pharmacol Exp Ther 2006, 316:969-982.
41. Lukovic L, de Jong W, de Wied D: Cardiovascular effects of substance P and capsaicin microinjected into the nucleus tractus solitarii of the rat. Brain Res 1987, 422:312-318.
42. Geraghty DP, Mazzone SB: Respiratory actions of vanilloid receptor agonists in the nucleus of the solitary tract: comparison of resiniferatoxin with non-pungent agents and anandamide. Br J Pharmacol 2002, 137:919-927.
43. Doyle MW, Bailey TW, Jin YH, Andresen MC: Vanilloid receptors presynaptically modulate cranial visceral afferent synaptic transmission in nucleus tractus sollitarius. J Neurosci 2002, 22:8222-8229.
44. Bailey TW, Jin YH, Doyle MW, Andresen MC: Vanilloid-sensitive afferents activate neurons with prominent A-type potassium currents in nucleus tractus solitarius. J Neurosci 2002, 22:8230-8237.
45. Rabe LS, Buck SH, Moreno L, Burks TF, Dafny N: Neurophysiological and thermoregulatory effects of capsaicin. Brain Res Bull 1980, 5:755-758.
46. Hajos M, Hjorth S, Carlsson A: Injection of capsaicin into the nucleus raphe dorsalis elicits heat loss in the rat. Neurosci Lett 1987, 75:199-204.
47. Singewald N, Philippu A: Release of neurotransmitters in the locus coeruleus. Prog Neurobiol 1998, 56:237-267.
48. Hajos M, Jancso G, Engberg G: Capsaicin-induced excitation of locus coerulous neurons. Acta Physiol Scand 1987, 129:415-420.
49. Marinelli S, Vaughan CW, Christie MJ, Connor M: Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus; in vitro. J Physiol 2002, 543:531-540.
50. Jancso-Gabor A, Szolcsanyi J, Jancso N: Stimulation and desensitization of the hypothalamic heat-sensitive structures by capsaicin in rats. J Physiol 1970, 208:449-459.
51. Karlsson U, Sundgren-Andersson AK, Johansson S, Krupp JJ: Capsaicin augments synaptic transmission in the rat medial preoptic nucleus. Brain Res 2005, 1043:1-11.
52. Andoh R, Shima K, Miyagawa T, Sakurada S, Kisara K, Ohsawa K, Takahashi M: Excitatory effects of dihydrocapsaicin on nociceptive neurons in the medial thalamus. Jpn J Pharmacol 1980, 30:599-605.
53. Andoh R, Sakurada S, Sato T, Takahashi N, Kisara. K: Potentiating effects of prostaglandin E2 on bradykinin and capsaicin responses in medial thalamic nociceptive neurons. Jpn J Pharmacol 1982, 32:81-89.
54. Ando R, Onodera K, Shima K, Kisara K: [Effects of capsaicin on spontaneous unit discharges in medial thalamic single neurons of cats (author's transl)]. Nippon Yakurigaku Zasshi 1977, 73:955-959.
55. Marinelli S, Pascucci T, Bernardi G, Puglisi-Allegra S, Mercuri NB: Activation of TRPV1 in the VTA excites dopaminergic neurons and increases chemical- and noxious-induced dopamine release in the nucleus accumbens. Neuropsychopharmacology 2005, 30:864-870.
56. Dawbarn D, Harmar AJ, Pycock CJ: Intranigral injection of capsaicin enhances motor activity and depletes nigral 5-hydroxytryptamine but not substance P. Neuropharmacology 1981, 20:341-346.
57. Hajos M, Engberg G, Nissbrandt H, Magnusson T, Carlsson A: Capsaicin-sensitive vasodilatatory mechanisms in the rat substantia nigra and striatum. J Neural Transm 1988, 74:129-139.
58. Marinelli S, Di Marzo V, Berretta N, Matias I, Maccarrone M, Bernardi G, Mercuri NB: Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors. J Neurosci 2003, 23:3136-3144.
59. Al-Hayani A, Wease KN, Ross RA, Pertwee RG, Davies SN: The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice. Neuropharmacology 2001, 41:1000-1005.
60. Kofalvi A, Oliveira CR, Cunha RA: Lack of evidence for functional TRPV(1) vanilloid receptors in rat hippocampal nerve terminals. Neurosci Lett 2006.
61. Salt TE, Hill RG: The effects of microiontophoretically applied capsaicin and substance P on single neurones in the rat and cat brain. Neurosci Lett 1980, 20:329-334.
62. Zhuo M: Canadian Association of Neuroscience review: Cellular and synaptic insights into physiological and pathological pain. EJLB-CIHR Michael Smith Chair in Neurosciences and Mental Health lecture. Can J Neurol Sci 2005, 32:27-36.
63. Toldi J, Joo F, Wolfe JR: Capsaicin differentially influences somatosensory cortical responses evoked by peripheral electrical or mechanical stimulation. Neuroscience 1992, 49:135-139.
64. Calejesan AA, Kim SJ, Zhuo M: Descending facilitatory modulation of a behavioral nociceptive response by stimulation in the adult rat anterior cingulate cortex. Eur J Pain 2000, 4:83-96.
65. Tang J, Ko S, Ding HK, Qiu CS, Calejesan AA, Zhuo M: Pavlovian fear memory induced by activation in the anterior cingulate cortex. Mol Pain 2005, 1:6.