The endogenous cannabinoid anandamide activates vanilloid receptors in the rat hippocampal slice

Neuropharmacology

Volumn 41, Issue 8, 2001, Pages 1000-1005

  Al Hayani, A ^a   Wease, K N ^a   Ross, R A ^a   Pertwee, R G ^a   Davies, S N ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Anandamide; Cannabinoid; Capsaicin; Hippocampus; Paired pulse depression; Vanilloid

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 2 ARACHIDONOYLGLYCEROL; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; ANANDAMIDE; CANNABINOID; CANNABINOID RECEPTOR ANTAGONIST; CAPSAICIN; CAPSAZEPINE; RESINIFERATOXIN; VANILLOID RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE;

ACTION POTENTIALS; ANIMALS; ARACHIDONIC ACIDS; CANNABINOIDS; CAPSAICIN; DITERPENES; GLYCERIDES; HIPPOCAMPUS; POLYUNSATURATED ALKAMIDES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DRUG;

EID: 0035662685     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00145-9     Document Type: Article

References (27)

1. Comparison of [H-3] resiniferatoxin binding by the vanilloid (capsaicin) receptor in dorsal root ganglia, spinal cord, dorsal vagal complex, sciatic and vagal nerve and urinary bladder of the rat
2. 3[H]resiniferatoxin by human and rat preoptic area, locus ceruleus, medial hypothalamus, reticular formation and ventral thalamus membrane preparations
3. Developmental regulation of CB1 receptor mediated inhibition of synaptic transmission in the rat hippocampal slice
4. Capsaicin affects the structure and phase organization of phospholipid membranes
5. The capsaicin receptor: A heat activated ion channel in the pain pathway
6. Intranigral injection of capsaicin enhances motor activity and depletes nigral 5-hydroxytryptamine but not substance P
7. Enzymatic - Synthesis and degredation of anandamide, a cannabinoid receptor agonist
8. Capsaicin and its analogs induce ion channels in planar lipid bilayers
9. 3 purinoceptor and IB4 binding sites
10. Capsaicin-induced excitation of locus coeruleus neurons
11. Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
12. A synaptic transmission in the hippocampus
13. Irreversible impairment of thermoregulation induced by capsaicin and similar pungent substances in rats and guinea pigs
14. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
15. Local circuit synaptic-interactions in hippocampal brain slices
16. Distribution of mRNA for vanilloid receptor subtype 1 (VR1), and VR1-like immunoreactivity, in the central nervous system of the rat and human
17. Correlation between cannabinoid mediated effects on paired pulse depression and induction of long term potentiation in the rat hippocampal slice
18. The ligand that came from within
19. Induction of vanilloid receptor channel activity by protein kinase C
20. Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens
21. Existence of capsaicin-sensitive glutamergic terminals in rat hypothalamus
22. The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)
23. Vanilloid (capsaicin) receptors and mechanisms
24. New perspectives on enigmatic vanilloid receptors
25. Vanilloid (capsaicin) receptors in the rat: Distribution in the brain, regional differences in the spinal cord, axonal transport to the periphery, and depletion by systemic vanilloid treatment
26. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide