Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist

Neuropharmacology

Volumn 46, Issue 1, 2004, Pages 133-149

  Gunthorpe, M J ^a   Rami, H K ^a   Jerman, J C ^a   Smart, D ^a   Gill, C H ^a   Soffin, E M ^a   Hannan, S Luis ^a   Lappin, S C ^a   Egerton, J ^a   Smith, G D ^a   Worby, A ^a   Howett, L ^a   Owen, D ^a   Nasir, S ^a   Davies, C H ^a   Thompson, M ^a   Wyman, P A ^a   Randall, A D ^a   Davis, J B ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Capsaicin; Ion channel; Pain; TRPV; TRPV1; VR1

Indexed keywords

ACID; CALCIUM ION; CAPSAICIN; CAPSAZEPINE; G PROTEIN COUPLED RECEPTOR; ION CHANNEL; RECEPTOR BLOCKING AGENT; SB 366791; UNCLASSIFIED DRUG; VANILLOID RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; ELECTROPHYSIOLOGY; HEAT; HIGH THROUGHPUT SCREENING; HIPPOCAMPUS; HUMAN; HUMAN CELL; HYPERPOLARIZATION; LOCUS CERULEUS; MALE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; RODENT; SYNAPTIC TRANSMISSION;

EID: 10744220213     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(03)00305-8     Document Type: Article

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