-
2
-
-
0030777012
-
The capsaicin receptor: A heat-activated ion channel in the pain pathway
-
Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: A heat-activated ion channel in the pain pathway. Nature 389:816-824
-
(1997)
Nature
, vol.389
, pp. 816-824
-
-
Caterina, M.J.1
Schumacher, M.A.2
Tominaga, M.3
Rosen, T.A.4
Levine, J.D.5
Julius, D.6
-
3
-
-
0017640292
-
A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain
-
Szolcsanyi J (1977) A pharmacological approach to elucidation of the role of different nerve fibres and receptor endings in mediation of pain. J Physiol (Paris) 73:251-259
-
(1977)
J. Physiol. (Paris)
, vol.73
, pp. 251-259
-
-
Szolcsanyi, J.1
-
4
-
-
0032970173
-
Vanilloid (capsaicin) receptors and mechanisms
-
Szallasi A, Blumberg PM (1999) Vanilloid (capsaicin) receptors and mechanisms. Pharmacol Rev 51:159-212
-
(1999)
Pharmacol. Rev.
, vol.51
, pp. 159-212
-
-
Szallasi, A.1
Blumberg, P.M.2
-
5
-
-
0028961828
-
NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea
-
Baluk P, Bertrand C, Geppetti P, McDonald DM, Nadel JA (1995) NK1 receptors mediate leukocyte adhesion in neurogenic inflammation in the rat trachea. Am J Physiol 268:L263-L269
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Baluk, P.1
Bertrand, C.2
Geppetti, P.3
McDonald, D.M.4
Nadel, J.A.5
-
6
-
-
0023485301
-
Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain
-
Markowitz S, Saito K, Moskowitz MA (1987) Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain. J Neurosci 7:4129-4136
-
(1987)
J. Neurosci.
, vol.7
, pp. 4129-4136
-
-
Markowitz, S.1
Saito, K.2
Moskowitz, M.A.3
-
7
-
-
0025791002
-
Neuroeffector functions of sensory fibres: Implications for headache mechanisms and drug actions
-
Moskowitz MA, Buzzi MG (1991) Neuroeffector functions of sensory fibres: implications for headache mechanisms and drug actions. J Neurol 238:S18-S22
-
(1991)
J. Neurol.
, vol.238
-
-
Moskowitz, M.A.1
Buzzi, M.G.2
-
8
-
-
0030834838
-
Ineffectiveness of neurokinin-1 antagonist in acute migraine: A crossover study
-
Goldstein DJ, Wang O, Saper JR, Stoltz R, Silberstein SD, Mathew NT (1997) Ineffectiveness of neurokinin-1 antagonist in acute migraine: A crossover study. Cephalalgia 17:785-790
-
(1997)
Cephalalgia
, vol.17
, pp. 785-790
-
-
Goldstein, D.J.1
Wang, O.2
Saper, J.R.3
Stoltz, R.4
Silberstein, S.D.5
Mathew, N.T.6
-
9
-
-
0037395801
-
RPR100893, a substance-P antagonist, is not effective in the treatment of migraine attacks
-
Diener HC (2003) RPR100893, a substance-P antagonist, is not effective in the treatment of migraine attacks. Cephalalgia 23:183-185
-
(2003)
Cephalalgia
, vol.23
, pp. 183-185
-
-
Diener, H.C.1
-
10
-
-
0025748690
-
Early and late effects of prolonged topical capsaicin on cutaneous sensibility and neurogenic vasodilatation in humans
-
Simone DA, Ochoa J (1991) Early and late effects of prolonged topical capsaicin on cutaneous sensibility and neurogenic vasodilatation in humans. Pain 47:285-294
-
(1991)
Pain
, vol.47
, pp. 285-294
-
-
Simone, D.A.1
Ochoa, J.2
-
11
-
-
0026743898
-
Capsaicin releases calcitonin gene-related peptide from the human iris and ciliary body in vitro
-
Geppetti P, Del Bianco E, Cecconi R, Tramontana M, Romani A, Theodorsson E (1992) Capsaicin releases calcitonin gene-related peptide from the human iris and ciliary body in vitro. Regul Pept 41:83-92
-
(1992)
Regul. Pept.
, vol.41
, pp. 83-92
-
-
Geppetti, P.1
Del Bianco, E.2
Cecconi, R.3
Tramontana, M.4
Romani, A.5
Theodorsson, E.6
-
12
-
-
0021997471
-
Calcitonin gene-related peptide is a potent vasodilator
-
Brain SD, Williams TJ, Tippins JR, Morris HR, MacIntyre I (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature 313:54-56
-
(1985)
Nature
, vol.313
, pp. 54-56
-
-
Brain, S.D.1
Williams, T.J.2
Tippins, J.R.3
Morris, H.R.4
MacIntyre, I.5
-
13
-
-
0026101211
-
Calcitonin gene-related peptide and human epicardial coronary arteries: Presence, release and vasodilator effects
-
Franco-Cereceda A (1991) Calcitonin gene-related peptide and human epicardial coronary arteries: Presence, release and vasodilator effects. Br J Pharmacol 102:506-510
-
(1991)
Br. J. Pharmacol.
, vol.102
, pp. 506-510
-
-
Franco-Cereceda, A.1
-
14
-
-
0021857460
-
Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide
-
Amara SG, Arriza JL, Leff SE, Swanson LW, Evans RM, Rosenfeld MG (1985) Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. Science 229:1094-1097
-
(1985)
Science
, vol.229
, pp. 1094-1097
-
-
Amara, S.G.1
Arriza, J.L.2
Leff, S.E.3
Swanson, L.W.4
Evans, R.M.5
Rosenfeld, M.G.6
-
15
-
-
0026612043
-
Characterization of CGRP1 and CGRP2 receptor subtypes
-
Quirion R, Van Rossum D, Dumont Y, St-Pierre S, Fournier A (1992) Characterization of CGRP1 and CGRP2 receptor subtypes. Ann N Y Acad Sci 657:88-105
-
(1992)
Ann. N. Y. Acad. Sci.
, vol.657
, pp. 88-105
-
-
Quirion, R.1
Van Rossum, D.2
Dumont, Y.3
St-Pierre, S.4
Fournier, A.5
-
16
-
-
0021223473
-
Isolation and characterization of human calcitonin gene-related peptide
-
Morris HR, Panico M, Etienne T, Tippins J, Girgis SI, MacIntyre I (1984) Isolation and characterization of human calcitonin gene-related peptide. Nature 308:746-748
-
(1984)
Nature
, vol.308
, pp. 746-748
-
-
Morris, H.R.1
Panico, M.2
Etienne, T.3
Tippins, J.4
Girgis, S.I.5
MacIntyre, I.6
-
17
-
-
0027197671
-
Adrenomedullin: A novel hypotensive peptide isolated from human pheochromocytoma
-
Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T (1993) Adrenomedullin: A novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 192:553-560
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.192
, pp. 553-560
-
-
Kitamura, K.1
Kangawa, K.2
Kawamoto, M.3
Ichiki, Y.4
Nakamura, S.5
Matsuo, H.6
Eto, T.7
-
18
-
-
0027965188
-
Endothelial cells actively synthesize and secrete adrenomedullin
-
Sugo S, Minamino N, Kangawa K, Miyamoto K, Kitamura K, Sakata J, Eto T, Matsuo H (1994) Endothelial cells actively synthesize and secrete adrenomedullin. Biochem Biophys Res Commun 201:1160-1166
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.201
, pp. 1160-1166
-
-
Sugo, S.1
Minamino, N.2
Kangawa, K.3
Miyamoto, K.4
Kitamura, K.5
Sakata, J.6
Eto, T.7
Matsuo, H.8
-
19
-
-
0023579739
-
Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients
-
Cooper GJS, Willis AC, Clark A, Turner RC, Sim RB, Reid KBM (1987) Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients. Proc Natl Acad Sci 84:8628-8632
-
(1987)
Proc. Natl. Acad. Sci.
, vol.84
, pp. 8628-8632
-
-
Cooper, G.J.S.1
Willis, A.C.2
Clark, A.3
Turner, R.C.4
Sim, R.B.5
Reid, K.B.M.6
-
20
-
-
0344638970
-
Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle
-
Cooper GJS, Leighton B, Dimitriadis GD, Parry-Billings M, Kowalchuk JM, Howland K, Rothbard JB, Willis AC, Reid KBM (1988) Amylin found in amyloid deposits in human type 2 diabetes mellitus may be a hormone that regulates glycogen metabolism in skeletal muscle. Proc Natl Acad Sci 85:7763-7766
-
(1988)
Proc. Natl. Acad. Sci.
, vol.85
, pp. 7763-7766
-
-
Cooper, G.J.S.1
Leighton, B.2
Dimitriadis, G.D.3
Parry-Billings, M.4
Kowalchuk, J.M.5
Howland, K.6
Rothbard, J.B.7
Willis, A.C.8
Reid, K.B.M.9
-
21
-
-
0023886266
-
Differential expression of [alpha]-CGRP and [beta]-CGRP by primary sensory neurons and enteric autonomic neurons of the rat
-
Mudderry PK, Ghatei MA, Spokes RA, Jonhs PM, Pierson AM, Hamid QA, Kanse S, Amara SG, Burrik JM, Legon S (1988) Differential expression of [alpha]-CGRP and [beta]-CGRP by primary sensory neurons and enteric autonomic neurons of the rat. Neuroscience 25:195-205
-
(1988)
Neuroscience
, vol.25
, pp. 195-205
-
-
Mudderry, P.K.1
Ghatei, M.A.2
Spokes, R.A.3
Jonhs, P.M.4
Pierson, A.M.5
Hamid, Q.A.6
Kanse, S.7
Amara, S.G.8
Burrik, J.M.9
Legon, S.10
-
22
-
-
0023096410
-
Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord
-
Petermann J, Born W, Chang J, Fischer J (1987) Identification in the human central nervous system, pituitary, and thyroid of a novel calcitonin gene-related peptide, and partial amino acid sequence in the spinal cord. J Biol Chem 262:542-545
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 542-545
-
-
Petermann, J.1
Born, W.2
Chang, J.3
Fischer, J.4
-
23
-
-
0033021524
-
Peripheral nerve regeneration and neurotrophic factors
-
Terenghi G (1999) Peripheral nerve regeneration and neurotrophic factors. J Anat 194:1-14
-
(1999)
J. Anat.
, vol.194
, pp. 1-14
-
-
Terenghi, G.1
-
24
-
-
0022470812
-
Human calcitonin gene related peptide: A potent endogenous vasodilator in man
-
Struthers AD, Brown MJ, Macdonald DW, Beacham JL, Stevenson JC, Morris HR, MacIntyre I (1986) Human calcitonin gene related peptide: A potent endogenous vasodilator in man. Clin Sci (Lond) 70:389-393
-
(1986)
Clin. Sci. (Lond.)
, vol.70
, pp. 389-393
-
-
Struthers, A.D.1
Brown, M.J.2
Macdonald, D.W.3
Beacham, J.L.4
Stevenson, J.C.5
Morris, H.R.6
MacIntyre, I.7
-
25
-
-
0024577744
-
Interactions between the tachykinins and calcitonin gene-related peptide lead to the modulation of oedema formation and blood flow in rat skin
-
Brain SD, Williams TJ (1989) Interactions between the tachykinins and calcitonin gene-related peptide lead to the modulation of oedema formation and blood flow in rat skin. Br J Pharmacol 97:77-82
-
(1989)
Br. J. Pharmacol.
, vol.97
, pp. 77-82
-
-
Brain, S.D.1
Williams, T.J.2
-
26
-
-
0034644582
-
Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction
-
Fernandez-Patron C, Stewart KG, Zhang Y, Koivunen E, Radomski MW, Davidge ST (2000) Vascular matrix metalloproteinase-2-dependent cleavage of calcitonin gene-related peptide promotes vasoconstriction. Circ Res 87:670-676
-
(2000)
Circ. Res.
, vol.87
, pp. 670-676
-
-
Fernandez-Patron, C.1
Stewart, K.G.2
Zhang, Y.3
Koivunen, E.4
Radomski, M.W.5
Davidge, S.T.6
-
27
-
-
0025822334
-
Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase
-
Katayama M, Nadel JA, Bunnett NW, Di Maria GU, Haxhiu M, Borson DB (1991) Catabolism of calcitonin gene-related peptide and substance P by neutral endopeptidase. Peptides 12:563-567
-
(1991)
Peptides
, vol.12
, pp. 563-567
-
-
Katayama, M.1
Nadel, J.A.2
Bunnett, N.W.3
Di Maria, G.U.4
Haxhiu, M.5
Borson, D.B.6
-
28
-
-
0024357838
-
Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity
-
Dennis T, Fournier A, St Pierre S, Quirion R (1989) Structure-activity profile of calcitonin gene-related peptide in peripheral and brain tissues. Evidence for receptor multiplicity. J Pharmacol Exp Ther 251:718-725
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 718-725
-
-
Dennis, T.1
Fournier, A.2
St. Pierre, S.3
Quirion, R.4
-
29
-
-
0024597810
-
Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37)
-
Chiba T, Yamaguchi A, Yamatani T, Nakamura A, Morishita T, Inui T, Fukase M, Noda T, Fujita T (1989) Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol Endocrinol Metab 256:E331-E335
-
(1989)
Am. J. Physiol. Endocrinol. Metab.
, vol.256
-
-
Chiba, T.1
Yamaguchi, A.2
Yamatani, T.3
Nakamura, A.4
Morishita, T.5
Inui, T.6
Fukase, M.7
Noda, T.8
Fujita, T.9
-
30
-
-
0027440296
-
A new calcitonin-receptor-like sequence in rat pulmonary blood vessels
-
Njuki F, Nicholl CG, Howard A, Mak JC, Barnes PJ, Girgis SI, Legon S (1993) A new calcitonin-receptor-like sequence in rat pulmonary blood vessels. Clin Sci (Lond) 85:385-388
-
(1993)
Clin. Sci. (Lond.)
, vol.85
, pp. 385-388
-
-
Njuki, F.1
Nicholl, C.G.2
Howard, A.3
Mak, J.C.4
Barnes, P.J.5
Girgis, S.I.6
Legon, S.7
-
31
-
-
0028872954
-
A human orphan calcitonin receptor-like structure
-
Fluhmann B, Muff R, Hunziker W, Fischer JA, Born W (1995) A human orphan calcitonin receptor-like structure. Biochem Biophys Res Commun 206:341-347
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.206
, pp. 341-347
-
-
Fluhmann, B.1
Muff, R.2
Hunziker, W.3
Fischer, J.A.4
Born, W.5
-
32
-
-
15844426346
-
A cDNA encoding the calcitonin gene-related peptide type 1 receptor
-
Aiyar N, Rand K, Elshourbagy NA, Zeng Z, Adamou JE, Bergsma DJ, Li Y (1996) A cDNA encoding the calcitonin gene-related peptide type 1 receptor. J Biol Chem 271:11325-11329
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11325-11329
-
-
Aiyar, N.1
Rand, K.2
Elshourbagy, N.A.3
Zeng, Z.4
Adamou, J.E.5
Bergsma, D.J.6
Li, Y.7
-
33
-
-
0032574982
-
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
-
McLatchie LM, Fraser NJ, Main MJ, Wise A, Brown J, Thompson N, Solari R, Lee MG, Foord SM (1998) RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 393:333-339
-
(1998)
Nature
, vol.393
, pp. 333-339
-
-
McLatchie, L.M.1
Fraser, N.J.2
Main, M.J.3
Wise, A.4
Brown, J.5
Thompson, N.6
Solari, R.7
Lee, M.G.8
Foord, S.M.9
-
34
-
-
0032826558
-
The N-terminus of RAMPs is a critical determinant of the glycosylation state and ligand binding of calcitonin receptor-like receptor
-
Foord SM, Wise A, Brown J, Main MJ, Fraser NJ (1999) The N-terminus of RAMPs is a critical determinant of the glycosylation state and ligand binding of calcitonin receptor-like receptor. Biochem Soc Trans 27:535-539
-
(1999)
Biochem. Soc. Trans.
, vol.27
, pp. 535-539
-
-
Foord, S.M.1
Wise, A.2
Brown, J.3
Main, M.J.4
Fraser, N.J.5
-
35
-
-
0033970471
-
Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist
-
Doods H, Hallermayer G, Wu D, Entzeroth M, Rudolf K, Engel W, Eberlein W (2000) Pharmacological profile of BIBN4096BS, the first selective small molecule CGRP antagonist. Br J Pharmacol 129:420-423
-
(2000)
Br. J. Pharmacol.
, vol.129
, pp. 420-423
-
-
Doods, H.1
Hallermayer, G.2
Wu, D.3
Entzeroth, M.4
Rudolf, K.5
Engel, W.6
Eberlein, W.7
-
36
-
-
0035831167
-
Characterisation of the effects of a nonpeptide CGRP receptor antagonist in SK-N-MC cells and isolated human cerebral arteries
-
Edvinsson L, Sams A, Jansen-Olesen I, Tajti J, Kane SA, Rutledge RZ, Koblan KS, Hill RG, Longmore J (2001) Characterisation of the effects of a nonpeptide CGRP receptor antagonist in SK-N-MC cells and isolated human cerebral arteries. Eur J Pharmacol 415:39-44
-
(2001)
Eur. J. Pharmacol.
, vol.415
, pp. 39-44
-
-
Edvinsson, L.1
Sams, A.2
Jansen-Olesen, I.3
Tajti, J.4
Kane, S.A.5
Rutledge, R.Z.6
Koblan, K.S.7
Hill, R.G.8
Longmore, J.9
-
37
-
-
0035129463
-
Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist
-
Aiyar N, Daines RA, Disa J, Chambers PA, Sauermelch CF, Quiniou M-J, Khandoudi N, Gout B, Douglas SA, Willette RN (2001) Pharmacology of SB-273779, a nonpeptide calcitonin gene-related peptide 1 receptor antagonist. J Pharmacol Exp Ther 296:768-775
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 768-775
-
-
Aiyar, N.1
Daines, R.A.2
Disa, J.3
Chambers, P.A.4
Sauermelch, C.F.5
Quiniou, M.-J.6
Khandoudi, N.7
Gout, B.8
Douglas, S.A.9
Willette, R.N.10
-
38
-
-
0033614984
-
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
-
Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sorgard M, Di Marzo V, Julius D, Hogestatt ED (1999) Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature 400:452-457
-
(1999)
Nature
, vol.400
, pp. 452-457
-
-
Zygmunt, P.M.1
Petersson, J.2
Andersson, D.A.3
Chuang, H.4
Sorgard, M.5
Di Marzo, V.6
Julius, D.7
Hogestatt, E.D.8
-
39
-
-
0004906771
-
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
-
Hwang SW, Cho H, Kwak J, Lee SY, Kang CJ, Jung J, Cho S, Min KH, Suh YG, Kim D, Oh U (2000) Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances. Proc Natl Acad Sci USA 97:6155-160
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6155-6160
-
-
Hwang, S.W.1
Cho, H.2
Kwak, J.3
Lee, S.Y.4
Kang, C.J.5
Jung, J.6
Cho, S.7
Min, K.H.8
Suh, Y.G.9
Kim, D.10
Oh, U.11
-
40
-
-
0037062411
-
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors
-
Huang SM, Bisogno T, Trevisani M, Al-Hayani A, De Petrocellis L, Fezza F, Tognetto M, Petros TJ, Krey JF, Chu CJ, Miller JD, Davies SN, Geppetti P, Walker JM, Di Marzo V (2002) An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors. Proc Natl Acad Sci USA 99:8400-8405
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8400-8405
-
-
Huang, S.M.1
Bisogno, T.2
Trevisani, M.3
Al-Hayani, A.4
De Petrocellis, L.5
Fezza, F.6
Tognetto, M.7
Petros, T.J.8
Krey, J.F.9
Chu, C.J.10
Miller, J.D.11
Davies, S.N.12
Geppetti, P.13
Walker, J.M.14
Di Marzo, V.15
-
41
-
-
0032169804
-
The cloned capsaicin receptor integrates multiple pain-producing stimuli
-
Tominaga M, Caterina MJ, Malmberg AB, Rosen TA, Gilbert H, Skinner K, Raumann BE, Basbaum AI, Julius D (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21:531-543
-
(1998)
Neuron
, vol.21
, pp. 531-543
-
-
Tominaga, M.1
Caterina, M.J.2
Malmberg, A.B.3
Rosen, T.A.4
Gilbert, H.5
Skinner, K.6
Raumann, B.E.7
Basbaum, A.I.8
Julius, D.9
-
42
-
-
0035927651
-
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
-
Chuang HH, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV, Julius D (2001) Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature 411:957-962
-
(2001)
Nature
, vol.411
, pp. 957-962
-
-
Chuang, H.H.1
Prescott, E.D.2
Kong, H.3
Shields, S.4
Jordt, S.E.5
Basbaum, A.I.6
Chao, M.V.7
Julius, D.8
-
43
-
-
0034700494
-
Induction of vanilloid receptor channel activity by protein kinase C
-
Premkumar LS, Ahern GP (2000) Induction of vanilloid receptor channel activity by protein kinase C. Nature 408:985-990
-
(2000)
Nature
, vol.408
, pp. 985-990
-
-
Premkumar, L.S.1
Ahern, G.P.2
-
44
-
-
85047696992
-
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1
-
Trevisani M, Smart D, Gunthorpe MJ, Tognetto M, Barbieri M, Campi B, Amadesi S, Gray J, Jerman JC, Brough SJ, Owen D, Smith GD, Randall AD, Harrison S, Bianchi A, Davis JB, Geppetti P (2002) Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1. Nat Neurosci 5:546-551
-
(2002)
Nat. Neurosci.
, vol.5
, pp. 546-551
-
-
Trevisani, M.1
Smart, D.2
Gunthorpe, M.J.3
Tognetto, M.4
Barbieri, M.5
Campi, B.6
Amadesi, S.7
Gray, J.8
Jerman, J.C.9
Brough, S.J.10
Owen, D.11
Smith, G.D.12
Randall, A.D.13
Harrison, S.14
Bianchi, A.15
Davis, J.B.16
Geppetti, P.17
-
45
-
-
0036499777
-
Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons
-
Segond von Banchet G, Pastor A, Biskup C, Schlegel C, Benndorf K, Schaible H-G (2002) Localization of functional calcitonin gene-related peptide binding sites in a subpopulation of cultured dorsal root ganglion neurons. Neuroscience 110:131-145
-
(2002)
Neuroscience
, vol.110
, pp. 131-145
-
-
Segond von Banchet, G.1
Pastor, A.2
Biskup, C.3
Schlegel, C.4
Benndorf, K.5
Schaible, H.-G.6
-
46
-
-
0025176672
-
Adrenergic modulation of calcitonin gene-related peptide (CGRP)- containing nerve-mediated vasodilation in the rat mesenteric resistance vessel
-
Kawasaki H, Nuki C, Saito A, Takasaki K (1990) Adrenergic modulation of calcitonin gene-related peptide (CGRP)-containing nerve-mediated vasodilation in the rat mesenteric resistance vessel. Brain Res 506:287-290
-
(1990)
Brain Res.
, vol.506
, pp. 287-290
-
-
Kawasaki, H.1
Nuki, C.2
Saito, A.3
Takasaki, K.4
-
47
-
-
0025174616
-
Role of calcitonin gene-related peptide-containing nerves in the vascular adrenergic neurotransmission
-
Kawasaki H, Nuki C, Saito A, Takasaki K (1990) Role of calcitonin gene-related peptide-containing nerves in the vascular adrenergic neurotransmission. J Pharmacol Exp Ther 252:403-409
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 403-409
-
-
Kawasaki, H.1
Nuki, C.2
Saito, A.3
Takasaki, K.4
-
48
-
-
0025373368
-
Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels
-
Nelson MT, Huang Y, Brayden JE, Hescheler J, Standen NB (1990) Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels. Nature 344:770-773
-
(1990)
Nature
, vol.344
, pp. 770-773
-
-
Nelson, M.T.1
Huang, Y.2
Brayden, J.E.3
Hescheler, J.4
Standen, N.B.5
-
49
-
-
1242288635
-
Pharmacological coupling and functional role for CGRP receptors in the vasodilation of rat pial arterioles
-
Hong KW, Yoo SE, Yu SS, Lee JY, Rhim BY (1996) Pharmacological coupling and functional role for CGRP receptors in the vasodilation of rat pial arterioles. Am J Physiol Heart Circ Physiol 270:H317-H323
-
(1996)
Am. J. Physiol. Heart Circ. Physiol.
, vol.270
-
-
Hong, K.W.1
Yoo, S.E.2
Yu, S.S.3
Lee, J.Y.4
Rhim, B.Y.5
-
50
-
-
0026803386
-
Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide
-
Gray DW, Marshall I (1992) Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide. Br J Pharmacol 107:691-696
-
(1992)
Br. J. Pharmacol.
, vol.107
, pp. 691-696
-
-
Gray, D.W.1
Marshall, I.2
-
51
-
-
0030909114
-
Mechanism of action of human calcitonin gene-related peptide in rabbit heart and in human mammary arteries
-
Raddino R, Pela G, Manca C, Barbagallo M, D'Aloia A, Passeri M, Visioli O (1997) Mechanism of action of human calcitonin gene-related peptide in rabbit heart and in human mammary arteries. J Cardiovasc Pharmacol 29:463-470
-
(1997)
J. Cardiovasc. Pharmacol.
, vol.29
, pp. 463-470
-
-
Raddino, R.1
Pela, G.2
Manca, C.3
Barbagallo, M.4
D'Aloia, A.5
Passeri, M.6
Visioli, O.7
-
52
-
-
0031896324
-
Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens
-
Wisskirchen FM, Burt RP, Marshall I (1998) Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br J Pharmacol 123:1673-1683
-
(1998)
Br. J. Pharmacol.
, vol.123
, pp. 1673-1683
-
-
Wisskirchen, F.M.1
Burt, R.P.2
Marshall, I.3
-
53
-
-
0032818548
-
Calcitonin gene-related peptide receptor independently stimulates 3pm,5pm-cyclic adenosine monophosphate and Ca2+ signaling pathways
-
Aiyar N, Disa J, Stadel JM, Lysko PG (1999) Calcitonin gene-related peptide receptor independently stimulates 3pm,5pm-cyclic adenosine monophosphate and Ca2+ signaling pathways. Mol Cell Biochem 197:179-185
-
(1999)
Mol. Cell Biochem.
, vol.197
, pp. 179-185
-
-
Aiyar, N.1
Disa, J.2
Stadel, J.M.3
Lysko, P.G.4
-
54
-
-
0031944896
-
Effects of adrenomedullin and calcitonin gene-related peptide on contractions of the rat aorta and porcine coronary artery
-
Yoshimoto R, Mitsui-Saito M, Ozaki H, Karaki H (1998) Effects of adrenomedullin and calcitonin gene-related peptide on contractions of the rat aorta and porcine coronary artery. Br J Pharmacol 123:1645-1654
-
(1998)
Br. J. Pharmacol.
, vol.123
, pp. 1645-1654
-
-
Yoshimoto, R.1
Mitsui-Saito, M.2
Ozaki, H.3
Karaki, H.4
-
56
-
-
0037976880
-
Concepts of migraine headache pathogenesis: Insights into mechanisms of chronicity and new drug targets
-
Welch KMA (2003) Concepts of migraine headache pathogenesis: Insights into mechanisms of chronicity and new drug targets. Neurol Sci 24:S149-S153
-
(2003)
Neurol. Sci.
, vol.24
-
-
Welch, K.M.A.1
-
57
-
-
0031837326
-
The antimigraine agent alniditan selectively constricts porcine carotid arteriovenous anastomoses via 5-HT1B/1D receptors
-
De Vries P, Willems EW, Heiligers JPC, Villalon CM, Saxena PR (1998) The antimigraine agent alniditan selectively constricts porcine carotid arteriovenous anastomoses via 5-HT1B/1D receptors. Eur J Pharmacol 351:193-201
-
(1998)
Eur. J. Pharmacol.
, vol.351
, pp. 193-201
-
-
De Vries, P.1
Willems, E.W.2
Heiligers, J.P.C.3
Villalon, C.M.4
Saxena, P.R.5
-
58
-
-
0000686675
-
The slow voltage variation of cortical spreading depression of activity
-
Leao AA (1951) The slow voltage variation of cortical spreading depression of activity. Electroencephalogr Clin Neurophysiol 3:315-321
-
(1951)
Electroencephalogr. Clin. Neurophysiol.
, vol.3
, pp. 315-321
-
-
Leao, A.A.1
-
59
-
-
0035341372
-
Cortical spreading depression and migraine: New insights from imaging?
-
James MF, Smith JM, Boniface SJ, Huang CLH, Leslie RA (2001) Cortical spreading depression and migraine: New insights from imaging? Trends Neurosci 24:266-271
-
(2001)
Trends Neurosci.
, vol.24
, pp. 266-271
-
-
James, M.F.1
Smith, J.M.2
Boniface, S.J.3
Huang, C.L.H.4
Leslie, R.A.5
-
60
-
-
0000128213
-
Clinical evaluation of a novel, potent, CNS penetrating NK1 receptor antagonist in the acute treatment of migraine
-
The GR205171 Clinical Study Group
-
Connor H, Bertin L, Gillies S, Beattie D, Ward P (1998) The GR205171 Clinical Study Group. Clinical evaluation of a novel, potent, CNS penetrating NK1 receptor antagonist in the acute treatment of migraine. Cephalalgia 18:392
-
(1998)
Cephalalgia
, vol.18
, pp. 392
-
-
Connor, H.1
Bertin, L.2
Gillies, S.3
Beattie, D.4
Ward, P.5
-
61
-
-
0034987623
-
Lanepitant, an NK-1 antagonist, in migraine prevention
-
Goldstein DJ, Offen WW, Klein EG, Phebus LA, Hipskind P, Johnson KW, Ryan RE Jr (2001) Lanepitant, an NK-1 antagonist, in migraine prevention. Cephalalgia 21:102-106.
-
(2001)
Cephalalgia
, vol.21
, pp. 102-106
-
-
Goldstein, D.J.1
Offen, W.W.2
Klein, E.G.3
Phebus, L.A.4
Hipskind, P.5
Johnson, K.W.6
Ryan Jr., R.E.7
-
62
-
-
4043057222
-
Blockade of CGRP receptors in the intracranial vasculature: A new target in the treatment of headache
-
Edvinsson L (2004) Blockade of CGRP receptors in the intracranial vasculature: A new target in the treatment of headache. Cephalalgia 24:611-622
-
(2004)
Cephalalgia
, vol.24
, pp. 611-622
-
-
Edvinsson, L.1
-
64
-
-
0025143541
-
Vasoactive peptide release in the extracerebral circulation of humans during migraine headache
-
Goadsby PJ, Edvinsson L, Ekman R (1990) Vasoactive peptide release in the extracerebral circulation of humans during migraine headache. Ann Neurol 28:183-187
-
(1990)
Ann. Neurol.
, vol.28
, pp. 183-187
-
-
Goadsby, P.J.1
Edvinsson, L.2
Ekman, R.3
-
65
-
-
0028891578
-
Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack
-
Fanciullacci M, Alessandri M, Figini M, Geppetti P, Michelacci S (1995) Increase in plasma calcitonin gene-related peptide from the extracerebral circulation during nitroglycerin-induced cluster headache attack. Pain 60:119-123
-
(1995)
Pain
, vol.60
, pp. 119-123
-
-
Fanciullacci, M.1
Alessandri, M.2
Figini, M.3
Geppetti, P.4
Michelacci, S.5
-
66
-
-
0036285460
-
CGRP may play a causative role in migraine
-
Lassen LH, Haderslev PA, Jacobsen VB, Iversen HK, Sperling B, Olesen J (2002) CGRP may play a causative role in migraine. Cephalalgia 22:54-61
-
(2002)
Cephalalgia
, vol.22
, pp. 54-61
-
-
Lassen, L.H.1
Haderslev, P.A.2
Jacobsen, V.B.3
Iversen, H.K.4
Sperling, B.5
Olesen, J.6
-
67
-
-
0344737766
-
NO-induced migraine attack: Strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release
-
Juhasz G, Zsombok T, Modos EA, Olajos S, Jakab B, Nemeth J, Szolcsanyi J, Vitrai J, Bagdy G (2003) NO-induced migraine attack: Strong increase in plasma calcitonin gene-related peptide (CGRP) concentration and negative correlation with platelet serotonin release. Pain 106:461-470
-
(2003)
Pain
, vol.106
, pp. 461-470
-
-
Juhasz, G.1
Zsombok, T.2
Modos, E.A.3
Olajos, S.4
Jakab, B.5
Nemeth, J.6
Szolcsanyi, J.7
Vitrai, J.8
Bagdy, G.9
-
68
-
-
0034524151
-
Triptans in migraine: A comparative review of pharmacology, pharmacokinetics and efficacy
-
Tfelt-Hansen P, De Vries P, Saxena PR (2000) Triptans in migraine: A comparative review of pharmacology, pharmacokinetics and efficacy. Drugs 60:1259-1287
-
(2000)
Drugs
, vol.60
, pp. 1259-1287
-
-
Tfelt-Hansen, P.1
De Vries, P.2
Saxena, P.R.3
-
69
-
-
0036632586
-
An immunocytochemical investigation of human trigeminal nucleus caudalis: CGRP, substance P and 5-HT1D-receptor immunoreactivities are expressed by trigeminal sensory fibres
-
Smith D, Hill RG, Edvinsson L, Longmore J (2002) An immunocytochemical investigation of human trigeminal nucleus caudalis: CGRP, substance P and 5-HT1D-receptor immunoreactivities are expressed by trigeminal sensory fibres. Cephalalgia 22:424-431
-
(2002)
Cephalalgia
, vol.22
, pp. 424-431
-
-
Smith, D.1
Hill, R.G.2
Edvinsson, L.3
Longmore, J.4
-
70
-
-
0001118764
-
Inhibition of trigeminal nociceptive afferents by adenosine A1 receptor activation: A novel approach towards the design of new anti-migraine compounds
-
Humphrey PP, Bland-Ward PA, Carruthers AM, Connor HE, Feniuk W, Honey AC, Thomas M (2001) Inhibition of trigeminal nociceptive afferents by adenosine A1 receptor activation: A novel approach towards the design of new anti-migraine compounds. Cephalalgia 21:268-269
-
(2001)
Cephalalgia
, vol.21
, pp. 268-269
-
-
Humphrey, P.P.1
Bland-Ward, P.A.2
Carruthers, A.M.3
Connor, H.E.4
Feniuk, W.5
Honey, A.C.6
Thomas, M.7
-
71
-
-
0036014933
-
Adenosine A1 receptor agonists inhibit trigeminovascular nociceptive transmission
-
Goadsby PJ, Hoskin KL, Storer RJ, Edvinsson L, Connor HE (2002) Adenosine A1 receptor agonists inhibit trigeminovascular nociceptive transmission. Brain 125:1392-1401
-
(2002)
Brain
, vol.125
, pp. 1392-1401
-
-
Goadsby, P.J.1
Hoskin, K.L.2
Storer, R.J.3
Edvinsson, L.4
Connor, H.E.5
-
72
-
-
0037616228
-
Effect of the adenosine A1 receptor agonist GR79236 on trigeminal nociception with blink reflex recordings in healthy human subjects
-
Giffin NJ, Kowacs F, Libri V, Williams P, Goadsby PJ, Kaube H (2003) Effect of the adenosine A1 receptor agonist GR79236 on trigeminal nociception with blink reflex recordings in healthy human subjects. Cephalalgia 23:287-292
-
(2003)
Cephalalgia
, vol.23
, pp. 287-292
-
-
Giffin, N.J.1
Kowacs, F.2
Libri, V.3
Williams, P.4
Goadsby, P.J.5
Kaube, H.6
-
73
-
-
10744227604
-
Isochroman-6-carboxamides as highly selective 5-HT1D agonists: Potential new treatment for migraine without cardiovascular side effects
-
Ennis MD, Ghazal NB, Hoffman RL, Smith MW, Schlachter SK, Lawson CF, Im WB, Pregenzer JF, Svensson KA, Lewis RA, Hall ED, Sutter DM, Harris LT, McCall RB (1998) Isochroman-6-carboxamides as highly selective 5-HT1D agonists: Potential new treatment for migraine without cardiovascular side effects. J Med Chem 41:2180-2183
-
(1998)
J. Med. Chem.
, vol.41
, pp. 2180-2183
-
-
Ennis, M.D.1
Ghazal, N.B.2
Hoffman, R.L.3
Smith, M.W.4
Schlachter, S.K.5
Lawson, C.F.6
Im, W.B.7
Pregenzer, J.F.8
Svensson, K.A.9
Lewis, R.A.10
Hall, E.D.11
Sutter, D.M.12
Harris, L.T.13
McCall, R.B.14
-
75
-
-
0035741529
-
Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine
-
Gomez-Mancilla B, Cutler N, Leibowitz M, Spierings E, Klapper J, Diamond S, Goldstein J, Smith T, Couch J, Fleishaker J, Azie N, Blunt D (2001) Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine. Cephalalgia 21:727-732
-
(2001)
Cephalalgia
, vol.21
, pp. 727-732
-
-
Gomez-Mancilla, B.1
Cutler, N.2
Leibowitz, M.3
Spierings, E.4
Klapper, J.5
Diamond, S.6
Goldstein, J.7
Smith, T.8
Couch, J.9
Fleishaker, J.10
Azie, N.11
Blunt, D.12
-
76
-
-
0000125663
-
Migraine treatment with selective with 5-ht1F receptor agonist (SSOFRA) LY334370
-
Goldstein J, Roon I, Offen W, Phebus LA, Johnson KW, Schaus JM, Vanlaar T, Ferrari MD (1999) Migraine treatment with selective with 5-ht1F receptor agonist (SSOFRA) LY334370. Cephalalgia 19:318
-
(1999)
Cephalalgia
, vol.19
, pp. 318
-
-
Goldstein, J.1
Roon, I.2
Offen, W.3
Phebus, L.A.4
Johnson, K.W.5
Schaus, J.M.6
Vanlaar, T.7
Ferrari, M.D.8
-
77
-
-
1542286029
-
CGRP-receptor antagonists-a fresh approach to migraine therapy?
-
Durham PL (2004) CGRP-receptor antagonists-a fresh approach to migraine therapy? N Engl J Med 350:1073-1075
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1073-1075
-
-
Durham, P.L.1
-
78
-
-
0034836381
-
Development of CGRP antagonists for the treatment of migraine
-
Doods H (2001) Development of CGRP antagonists for the treatment of migraine. Curr Opin Investig Drugs 2:1261-1268
-
(2001)
Curr. Opin. Investig. Drugs
, vol.2
, pp. 1261-1268
-
-
Doods, H.1
-
79
-
-
0041880691
-
Effects of BIBN4096BS on cardiac output distribution and on CGRP-induced carotid haemodynamic responses in the pig
-
Kapoor K, Arulmani U, Heiligers JPC, Willems EW, Doods H, Villalon CM, Saxena PR (2003) Effects of BIBN4096BS on cardiac output distribution and on CGRP-induced carotid haemodynamic responses in the pig. Eur J Pharmacol 475:69-77
-
(2003)
Eur. J. Pharmacol.
, vol.475
, pp. 69-77
-
-
Kapoor, K.1
Arulmani, U.2
Heiligers, J.P.C.3
Willems, E.W.4
Doods, H.5
Villalon, C.M.6
Saxena, P.R.7
-
80
-
-
1542346238
-
Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine
-
Olesen J, Diener HC, Husstedt IW, Goadsby PJ, Hall D, Meier U, Pollentier S, Lesko LM (2004) Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine. N Engl J Med 350:1104-1110
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1104-1110
-
-
Olesen, J.1
Diener, H.C.2
Husstedt, I.W.3
Goadsby, P.J.4
Hall, D.5
Meier, U.6
Pollentier, S.7
Lesko, L.M.8
-
81
-
-
13244252481
-
The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers
-
Petersen K, Birk S, Lassen L, Kruuse C, Jonassen O, Lesko L, Olesen J (2005) The CGRP-antagonist, BIBN4096BS does not affect cerebral or systemic haemodynamics in healthy volunteers. Cephalalgia 25:139-147
-
(2005)
Cephalalgia
, vol.25
, pp. 139-147
-
-
Petersen, K.1
Birk, S.2
Lassen, L.3
Kruuse, C.4
Jonassen, O.5
Lesko, L.6
Olesen, J.7
|