Proteinase-Activated Receptor 2-Mediated Potentiation of Transient Receptor Potential Vanilloid Subfamily 1 Activity Reveals a Mechanism for Proteinase-Induced Inflammatory Pain

Journal of Neuroscience

Volumn 24, Issue 18, 2004, Pages 4293-4299

  Dai, Yi ^a   Moriyama, Tomoko ^b   Higashi, Tomohiro ^b   Togashi, Kazuya ^b   Kobayashi, Kimiko ^a   Yamanaka, Hiroki ^a   Tominaga, Makoto ^b   Noguchi, Koichi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

^b MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Inflammatory pain; Mechanical allodynia; PKC; Proteinase activated receptor; Thermal hyperalgesia; TRPV1

Indexed keywords

CALPHOSTIN C; CAPSAICIN; CATION CHANNEL; PROTEIN FOS; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 2 AGONIST; PROTEINASE ACTIVATED RECEPTOR 3; PROTON; TRANSIENT RECEPTOR POTENTIAL VANILLOID RECEPTOR 1; TRYPSIN; TRYPTASE; UNCLASSIFIED DRUG; VANILLOID RECEPTOR;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; HYPERALGESIA; INFLAMMATION; ION CURRENT; MALE; MOUSE; MOUSE STRAIN; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PAIN; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SENSORY NERVE; SPINAL CORD; SPINAL GANGLION; TEMPERATURE DEPENDENCE; THERMAL STIMULATION; TISSUE INJURY; TRPV1 CURRENT;

ANIMALS; CELLS, CULTURED; ENDOPEPTIDASES; ENZYME INHIBITORS; GANGLIA, SPINAL; HUMANS; HYPERALGESIA; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PAIN; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTOR, PAR-1; RECEPTOR, PAR-2; RECEPTORS, DRUG; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; SPINAL CORD; TEMPERATURE; TRANSFECTION;

EID: 2442468123     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0454-04.2004     Document Type: Article

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